| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T220 |
0-127 |
Sentence |
denotes |
In addition, the gold nanoparticles (AuNPs)-based nanomaterials also have good application prospects in anti-novel coronavirus. |
| T221 |
128-273 |
Sentence |
denotes |
An electrochemical immunosensor based on an array of AuNPs-modified carbon electrodes was used for the determination of MERS-CoV (Fig. 8 ) [131]. |
| T222 |
274-463 |
Sentence |
denotes |
Highly sulfonated gold nanoparticles and heparin coated AuNPs with no cytotoxicity displayed broad-spectrum virucidal properties against HSV, HPV, RSV, dengue and lentivirus in vitro [132]. |
| T223 |
464-597 |
Sentence |
denotes |
S protein plays a key role in the pathogenesis of coronavirus, and it is considered a primary target for vaccine preparation [8,133]. |
| T224 |
598-815 |
Sentence |
denotes |
Virus like particles (sVLPs) were prepared by protein corona formation with IBV S protein as a model antigen and incubated with 100 nm AuNPs in a solution containing an optimized concentration of viral proteins [133]. |
| T225 |
816-1086 |
Sentence |
denotes |
As compared to inoculation with free proteins, vaccination with the sVLPs showed enhanced lymphatic antigen delivery, stronger antibody titers, increased splenic T-cell response, and reduced infection-associated symptoms in an avian model of coronavirus infection [133]. |
| T226 |
1087-1234 |
Sentence |
denotes |
The study demonstrates a simple and reliable method in bridging viral antigens with synthetic nanoparticles for improved vaccine application [133]. |
| T227 |
1235-1274 |
Sentence |
denotes |
Fig. 8 COV immunosensor array chip (a). |
| T228 |
1275-1393 |
Sentence |
denotes |
The immunosensor fabrication steps (b), the detection process of the competitive immunosensor for the virus (c) [131]. |
