Gene_Chemical

Documents (109) JSON TSV

source DB	source ID	text	size	updated at	# proj.	updated_at
PubMed	16825437	Nordic collaborative study of the BARD1 Cys557Ser allele in 3956 patients with cancer: enrichment in familial BRCA1/BRCA2 mutation-negative breast cancer but not in other malignancies. BACKGROUND: BAR	1.87 KB	2015-11-19	6	-
PubMed	16835864	Characterization of CHEK2 mutations in prostate cancer. The checkpoint kinase 2 (CHEK2, also known as CHK2) is a tumor suppressor that participates in the DNA damage-signaling pathway. It is phosphory	1.37 KB	2015-11-19	6	-
PubMed	16941491	Unique substitution of CHEK2 and TP53 mutations implicated in primary prostate tumors and cancer cell lines. Genetic defects in CHEK2 and TP53 have been implicated in prostate cancer development. Howe	1.36 KB	2015-11-20	5	-
PubMed	16963262	Identification of germline MLH1 alterations in familial prostate cancer. Several linkage and loss of heterozygosity (LOH) analyses suggest that the region 3p21-p26, which is a chromosomal location of	1.77 KB	2015-11-20	5	-
PubMed	16969499	Missense mutations of BRCA1 gene affect the binding with p53 both in vitro and in vivo. Women with BRCA1 gene mutations have an increased risk for breast and ovarian cancer (BOC). Classification of mi	2 KB	2015-11-20	4	-
PubMed	17001622	Characterization of the breast cancer associated ATM 7271T>G (V2424G) mutation by gene expression profiling. Mutations in ATM are responsible for the autosomal recessive disorder ataxia telangiectasia	1.79 KB	2015-11-23	6	-
PubMed	17020975	RNASEL gene polymorphisms and the risk of prostate cancer: a meta-analysis. PURPOSE: Studies revealing conflicting results on the role of RNASEL polymorphisms Glu265X, Arg462Gln, and Asp541Glu on pros	1.69 KB	2015-11-23	6	-
PubMed	17130833	Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion. Chemokine receptor CX	1.89 KB	2015-11-23	4	-
PubMed	17217814	[Prevalence of Val158Met polymorphism in COMT gene on non-BRCA1/2 hereditary breast cancer]. OBJECTIVE: To explore the prevalence of Val158Met polymorphism in Catechol-O-methyltransferase (COMT) gene	1.59 KB	2015-12-24	3	-
PubMed	17317153	BRCA1 promoter deletions in young women with breast cancer and a strong family history: a population-based study. Women diagnosed with breast cancer before the age of 40 years who have a strong family	1.35 KB	2015-11-23	6	-