Gene_Chemical

Documents (109) JSON TSV

source DB	source ID	text	size	updated at	# proj.	updated_at
PubMed	16280053	Mutation analysis of FANCD2, BRIP1/BACH1, LMO4 and SFN in familial breast cancer. INTRODUCTION: Mutations in known predisposition genes account for only about a third of all multiple-case breast cance	1.81 KB	2015-11-19	6	-
PubMed	16282370	Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization. Activation of signal transduction kinase cascades is known to alter androgen receptor (AR) activit	1.63 KB	2015-11-19	3	-
PubMed	16333312	BARD1 variants Cys557Ser and Val507Met in breast cancer predisposition. BARD1 (BRCA1-associated RING-domain 1) is a tumor suppressor whose protein product interacts with BRCA1, and in which rare somat	1.65 KB	2015-11-19	4	-
PubMed	16434975	The R273H p53 mutation can facilitate the androgen-independent growth of LNCaP by a mechanism that involves H2 relaxin and its cognate receptor LGR7. Mutations in p53 occur at a rate of approximately	1.46 KB	2015-11-23	2	-
PubMed	16503999	HFE H63D mutation frequency shows an increase in Turkish women with breast cancer. BACKGROUND: The hereditary hemochromatosis gene HFE plays a pivotal role in iron homeostasis. The association between	1.25 KB	2015-11-19	6	-
PubMed	16563154	Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriers. BACKGROUND: The MDM2 gene encodes a negative regulator of the p53 tumour suppressor protei	1.39 KB	2015-11-19	3	-
PubMed	16652348	The ATM missense mutation p.Ser49Cys (c.146C>G) and the risk of breast cancer. Homozygous mutation in the ATM gene causes ataxia telangiectasia and heterozygous mutation carriers may be at increased r	1.16 KB	2015-11-19	5	-
PubMed	16741917	The DU145 human prostate carcinoma cell line harbors a temperature-sensitive allele of p53. BACKGROUND: Some nuances of mutant and wild-type p53 activity have been uncovered utilizing temperature sens	1019 Bytes	2015-11-19	4	-
PubMed	16760288	Y179C, F486L and N550H are BRCA1 variants that may be associated with breast cancer in a Sicilian family: results of a 5-year GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study. BACKGR	1.42 KB	2015-11-19	5	-
PubMed	16822847	FGFR4 Arg388 allele is associated with resistance to adjuvant therapy in primary breast cancer. PURPOSE: A recent study presented first evidence that a single nucleotide polymorphism (SNP) at codon 38	1.88 KB	2015-11-19	5	-