Gene_Chemical

Documents (109) JSON TSV

source DB	source ID	text	size	updated at	# proj.	updated_at
PubMed	17336451	Uncoupling of hormone-dependence from chaperone-dependence in the L701H mutation of the androgen receptor. The mechanisms underlying androgen receptor (AR)-mediated progression of prostate cancer foll	1.55 KB	2015-11-23	5	-
PubMed	17427234	Composite adrenal anaplastic neuroblastoma and virilizing adrenocortical tumor with germline TP53 R248W mutation. Composite tumors are extremely rare. Such tumors in adrenal glands are usually of neur	792 Bytes	2017-09-11	13	-
PubMed	17443496	Mutations and polymorphisms of the p21B transcript in breast cancer. p21(WAF1/CIP1), transcribed from the CDKN1A locus, plays a key role executing p53-induced growth arrest. The recent discovery that	1.35 KB	2015-12-24	2	-
PubMed	17487399	VEGF transcription and mRNA stability are altered by WT1 not DDS(R384W) expression in LNCaP cells. To identify physiologically relevant WT1 transcriptional target genes in prostate cancer cells, we ha	2.16 KB	2015-11-23	3	-
PubMed	17493881	Thermal unfolding of human BRCA1 BRCT-domain variants. Missense mutations at the BRCT domain of human BRCA1 protein have been associated with an elevated risk for hereditary breast/ovarian cancer. The	1.37 KB	2015-12-27	14	-
PubMed	17502119	ATM missense variant P1054R predisposes to prostate cancer. BACKGROUND: Prostate cancer is associated with defective DNA strand break repair after DNA damage leading to genetic instability and prostat	2.05 KB	2015-11-23	6	-
PubMed	17517479	Possession of ATM sequence variants as predictor for late normal tissue responses in breast cancer patients treated with radiotherapy. PURPOSE: The ATM gene product is a central component of cell cycl	1.81 KB	2015-11-23	6	-
PubMed	17531442	Identification of sequences that target BRCA1 to nuclear foci following alkylative DNA damage. BRCA1 is a tumor suppressor involved in the maintenance of genome integrity. BRCA1 co-localizes with DNA	1.69 KB	2015-12-26	2	-
PubMed	17541742	Germline TP53 mutations in BRCA1 and BRCA2 mutation-negative French Canadian breast cancer families. About 40% of French Canadian breast and/or ovarian cancer families harbor germline BRCA1 or BRCA1 m	1.74 KB	2015-11-23	6	-
PubMed	17550384	Somatic mutations of BECN1, an autophagy-related gene, in human cancers. Evasion of programmed cell death (PCD) is one of the hallmarks of human cancers. It is well known that not only apoptosis, but	1.59 KB	2015-11-23	4	-