PMC:7239617 / 1124-1927 JSONTXT

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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7239617","sourcedb":"PMC","sourceid":"7239617","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7239617","text":"Parallelling what has been reported in influenza patients, we designed this prospective observational study to investigate IPA risk in critically ill patients with COVID-19. The patients were classified by means of the EORTC-MSG criteria5 (if immunocompromised) or the influenza-associated IPA criteria4 combined with serum β-D-glucan and quantitative real-time PCR (qPCR)7 done in the serum or pulmonary specimens (if non-immunocompromised). Putative IPA was considered if Aspergillus spp were identified in BAL culture; or if two of the following conditions were met (ie, presence of Aspergillus spp in bronchial aspiration [BA] culture; positive Aspergillus fumigatus qPCR in BAL, BA, or serum;8 galactomannan index \u003e0·8 in BAL;5 galactomannan index \u003e0·5 in serum; and β-D-glucan \u003e80 pg/mL in 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