Id |
Subject |
Object |
Predicate |
Lexical cue |
T6 |
741-746 |
Protein |
denotes |
IL-1β |
T7 |
748-752 |
Protein |
denotes |
IL-6 |
T8 |
758-762 |
Protein |
denotes |
MMP9 |
T9 |
843-847 |
Protein |
denotes |
MMP9 |
T10 |
1002-1006 |
Protein |
denotes |
MMP9 |
T11 |
1150-1157 |
Negative_regulation |
denotes |
absence |
T606 |
2210-2218 |
Negative_regulation |
denotes |
knockout |
T2032 |
5409-5418 |
Gene_expression |
denotes |
expressed |
T3097 |
7817-7824 |
Protein |
denotes |
β-actin |
T3370 |
8743-8747 |
Protein |
denotes |
MMP9 |
T4040 |
9643-9661 |
Protein |
denotes |
interleukin-1 beta |
T4041 |
9663-9668 |
Protein |
denotes |
IL-1β |
T4042 |
9675-9688 |
Protein |
denotes |
interleukin-6 |
T4043 |
9690-9694 |
Protein |
denotes |
IL-6 |
T4372 |
11111-11115 |
Protein |
denotes |
MMP9 |
T4373 |
11367-11371 |
Protein |
denotes |
MMP9 |
T4843 |
11677-11686 |
Negative_regulation |
denotes |
Depletion |
T5102 |
12237-12247 |
Negative_regulation |
denotes |
Disruption |
T5103 |
12256-12264 |
Positive_regulation |
denotes |
Enhanced |
T5104 |
12265-12277 |
Positive_regulation |
denotes |
Upregulation |
T5369 |
12867-12872 |
Protein |
denotes |
IL-1β |
T5370 |
12878-12882 |
Protein |
denotes |
IL-6 |
T5381 |
12887-12896 |
Regulation |
denotes |
regulated |
T5382 |
13175-13184 |
Negative_regulation |
denotes |
deficient |
T5371 |
13349-13354 |
Protein |
denotes |
IL-1β |
T5372 |
13360-13364 |
Protein |
denotes |
IL-6 |
T5383 |
13460-13471 |
Transcription |
denotes |
mRNA levels |
T5373 |
13482-13487 |
Protein |
denotes |
IL-1β |
T5374 |
13493-13497 |
Protein |
denotes |
IL-6 |
T5384 |
13503-13512 |
Positive_regulation |
denotes |
increased |
T5375 |
13801-13806 |
Protein |
denotes |
IL-1β |
T5376 |
13849-13853 |
Protein |
denotes |
IL-6 |
T5385 |
13952-13963 |
Positive_regulation |
denotes |
upregulated |
T5377 |
14223-14227 |
Protein |
denotes |
IL-6 |
T5378 |
14232-14237 |
Protein |
denotes |
IL-1β |
T5379 |
14243-14247 |
Protein |
denotes |
IL-6 |
T5380 |
14354-14359 |
Protein |
denotes |
IL-1β |
T6446 |
14497-14501 |
Protein |
denotes |
MMP9 |
T6447 |
14573-14577 |
Protein |
denotes |
MMP9 |
T6448 |
14730-14734 |
Protein |
denotes |
MMP9 |
T6453 |
14828-14838 |
Gene_expression |
denotes |
Expression |
T6449 |
14842-14846 |
Protein |
denotes |
MMP9 |
T6450 |
14965-14969 |
Protein |
denotes |
MMP9 |
T6451 |
15134-15138 |
Protein |
denotes |
MMP9 |
T6452 |
15296-15300 |
Protein |
denotes |
MMP9 |
T7080 |
15482-15489 |
Positive_regulation |
denotes |
induced |
T7081 |
15494-15506 |
Positive_regulation |
denotes |
upregulation |
T7082 |
15541-15555 |
Positive_regulation |
denotes |
overexpression |
T7052 |
15566-15571 |
Protein |
denotes |
IL-1β |
T7053 |
15573-15577 |
Protein |
denotes |
IL-6 |
T7054 |
15583-15587 |
Protein |
denotes |
MMP9 |
T7083 |
15961-15966 |
Binding |
denotes |
binds |
T7055 |
16027-16031 |
Protein |
denotes |
MMP9 |
T7056 |
16093-16098 |
Protein |
denotes |
IL-1β |
T7057 |
16104-16108 |
Protein |
denotes |
IL-6 |
T7058 |
16263-16267 |
Protein |
denotes |
MMP9 |
T7059 |
16463-16468 |
Protein |
denotes |
IL-1β |
T7060 |
16496-16500 |
Protein |
denotes |
MMP9 |
T7061 |
16529-16533 |
Protein |
denotes |
IL-6 |
T7062 |
16560-16564 |
Protein |
denotes |
MMP9 |
T7063 |
16616-16621 |
Protein |
denotes |
IL-1β |
T7064 |
17245-17261 |
Protein |
denotes |
heme oxygenase-1 |
T7065 |
17263-17267 |
Protein |
denotes |
HO-1 |
T7084 |
17660-17669 |
Negative_regulation |
denotes |
deficient |
T7085 |
17707-17716 |
Negative_regulation |
denotes |
Depletion |
T7086 |
17837-17851 |
Positive_regulation |
denotes |
overexpression |
T7066 |
17862-17867 |
Protein |
denotes |
IL-1β |
T7067 |
17869-17873 |
Protein |
denotes |
IL-6 |
T7068 |
17879-17883 |
Protein |
denotes |
MMP9 |
T7087 |
17942-17950 |
Negative_regulation |
denotes |
knockout |
T7088 |
18329-18336 |
Negative_regulation |
denotes |
inhibit |
T7089 |
18345-18360 |
Phosphorylation |
denotes |
phosphorylation |
T7069 |
18365-18368 |
Protein |
denotes |
p65 |
T7090 |
18383-18390 |
Entity |
denotes |
nuclear |
T7091 |
18391-18404 |
Localization |
denotes |
translocation |
T7092 |
18519-18529 |
Negative_regulation |
denotes |
attenuated |
T7093 |
18643-18652 |
Negative_regulation |
denotes |
depletion |
T7094 |
19001-19010 |
Negative_regulation |
denotes |
deficient |
T7095 |
19093-19100 |
Negative_regulation |
denotes |
inhibit |
T7070 |
19138-19141 |
Protein |
denotes |
p65 |
T7096 |
19150-19159 |
Negative_regulation |
denotes |
repressed |
T7097 |
19221-19232 |
Binding |
denotes |
interaction |
T7098 |
19250-19256 |
Entity |
denotes |
domain |
T7099 |
19403-19412 |
Regulation |
denotes |
regulated |
T7100 |
19824-19834 |
Gene_expression |
denotes |
expression |
T7071 |
19845-19850 |
Protein |
denotes |
IL-1β |
T7072 |
19856-19860 |
Protein |
denotes |
IL-6 |
T7073 |
20004-20008 |
Protein |
denotes |
MMP9 |
T7101 |
20334-20345 |
Positive_regulation |
denotes |
upregulated |
T7102 |
20346-20356 |
Gene_expression |
denotes |
expression |
T7074 |
20367-20372 |
Protein |
denotes |
IL-1β |
T7075 |
20374-20378 |
Protein |
denotes |
IL-6 |
T7076 |
20384-20388 |
Protein |
denotes |
MMP9 |
T7103 |
20397-20405 |
Negative_regulation |
denotes |
knockout |
T7104 |
20473-20482 |
Negative_regulation |
denotes |
depletion |
T7105 |
20491-20498 |
Positive_regulation |
denotes |
induced |
T7106 |
20503-20513 |
Positive_regulation |
denotes |
activation |
T7107 |
20531-20541 |
Gene_expression |
denotes |
expression |
T7077 |
20552-20557 |
Protein |
denotes |
IL-1β |
T7078 |
20559-20563 |
Protein |
denotes |
IL-6 |
T7079 |
20569-20573 |
Protein |
denotes |
MMP9 |
R3486 |
T4041 |
T4040 |
equivalentTo |
IL-1β,interleukin-1 beta |
R3487 |
T4043 |
T4042 |
equivalentTo |
IL-6,interleukin-6 |
R4343 |
T5104 |
T5103 |
themeOf |
Upregulation,Enhanced |
R4554 |
T5369 |
T5381 |
themeOf |
IL-1β,regulated |
R4555 |
T5370 |
T5381 |
themeOf |
IL-6,regulated |
R4556 |
T5373 |
T5383 |
themeOf |
IL-1β,mRNA levels |
R4557 |
T5373 |
T5384 |
themeOf |
IL-1β,increased |
R4558 |
T5374 |
T5384 |
themeOf |
IL-6,increased |
R4559 |
T5374 |
T5383 |
themeOf |
IL-6,mRNA levels |
R4560 |
T5383 |
T5384 |
themeOf |
mRNA levels,increased |
R5371 |
T6449 |
T6453 |
themeOf |
MMP9,Expression |
R5809 |
T7052 |
T7081 |
themeOf |
IL-1β,upregulation |
R5810 |
T7052 |
T7082 |
themeOf |
IL-1β,overexpression |
R5811 |
T7053 |
T7082 |
themeOf |
IL-6,overexpression |
R5812 |
T7054 |
T7082 |
themeOf |
MMP9,overexpression |
R5813 |
T7065 |
T7064 |
equivalentTo |
HO-1,heme oxygenase-1 |
R5814 |
T7066 |
T7086 |
themeOf |
IL-1β,overexpression |
R5815 |
T7067 |
T7086 |
themeOf |
IL-6,overexpression |
R5816 |
T7068 |
T7086 |
themeOf |
MMP9,overexpression |
R5817 |
T7069 |
T7091 |
themeOf |
p65,translocation |
R5818 |
T7070 |
T7097 |
themeOf |
p65,interaction |
R5819 |
T7071 |
T7100 |
themeOf |
IL-1β,expression |
R5820 |
T7072 |
T7100 |
themeOf |
IL-6,expression |
R5821 |
T7074 |
T7102 |
themeOf |
IL-1β,expression |
R5822 |
T7075 |
T7102 |
themeOf |
IL-6,expression |
R5823 |
T7076 |
T7102 |
themeOf |
MMP9,expression |
R5824 |
T7077 |
T7107 |
themeOf |
IL-1β,expression |
R5825 |
T7078 |
T7107 |
themeOf |
IL-6,expression |
R5826 |
T7079 |
T7107 |
themeOf |
MMP9,expression |
R5827 |
T7081 |
T7080 |
themeOf |
upregulation,induced |
R5828 |
T7089 |
T7088 |
themeOf |
phosphorylation,inhibit |
R5829 |
T7090 |
T7091 |
locationOf |
nuclear,translocation |
R5830 |
T7091 |
T7088 |
themeOf |
translocation,inhibit |
R5831 |
T7097 |
T7096 |
causeOf |
interaction,repressed |
R5832 |
T7102 |
T7101 |
themeOf |
expression,upregulated |
R5833 |
T7106 |
T7105 |
themeOf |
activation,induced |