| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T128 |
0-9 |
Positive_regulation |
denotes |
Increased |
| T93 |
10-24 |
Protein |
denotes |
interleukin-17 |
| T129 |
10-24 |
Protein |
denotes |
interleukin-17 |
| T130 |
25-35 |
Gene_expression |
denotes |
production |
| T94 |
68-71 |
Protein |
denotes |
Akt |
| T131 |
68-71 |
Protein |
denotes |
Akt |
| T132 |
273-292 |
Protein |
denotes |
Interleukin (IL)-17 |
| T95 |
273-292 |
Protein |
denotes |
Interleukin (IL)-17 |
| T133 |
504-509 |
Protein |
denotes |
IL-17 |
| T96 |
504-509 |
Protein |
denotes |
IL-17 |
| T134 |
600-605 |
Protein |
denotes |
IL-15 |
| T97 |
600-605 |
Protein |
denotes |
IL-15 |
| T135 |
610-615 |
Protein |
denotes |
IL-23 |
| T98 |
610-615 |
Protein |
denotes |
IL-23 |
| T136 |
639-647 |
Regulation |
denotes |
regulate |
| T137 |
648-653 |
Protein |
denotes |
IL-17 |
| T99 |
648-653 |
Protein |
denotes |
IL-17 |
| T138 |
654-664 |
Gene_expression |
denotes |
production |
| T139 |
708-716 |
Regulation |
denotes |
regulate |
| T140 |
717-722 |
Protein |
denotes |
IL-17 |
| T100 |
717-722 |
Protein |
denotes |
IL-17 |
| T141 |
723-733 |
Gene_expression |
denotes |
production |
| T142 |
837-840 |
Protein |
denotes |
Akt |
| T101 |
837-840 |
Protein |
denotes |
Akt |
| T143 |
856-866 |
Regulation |
denotes |
regulation |
| T144 |
870-875 |
Protein |
denotes |
IL-17 |
| T102 |
870-875 |
Protein |
denotes |
IL-17 |
| T145 |
876-886 |
Gene_expression |
denotes |
production |
| T146 |
1044-1048 |
Protein |
denotes |
CD28 |
| T103 |
1044-1048 |
Protein |
denotes |
CD28 |
| T147 |
1050-1068 |
Protein |
denotes |
phytohemagglutinin |
| T104 |
1050-1068 |
Protein |
denotes |
phytohemagglutinin |
| T148 |
1070-1073 |
Protein |
denotes |
PHA |
| T105 |
1070-1073 |
Protein |
denotes |
PHA |
| T149 |
1126-1131 |
Protein |
denotes |
IL-17 |
| T106 |
1126-1131 |
Protein |
denotes |
IL-17 |
| T150 |
1258-1268 |
Gene_expression |
denotes |
production |
| T151 |
1272-1277 |
Protein |
denotes |
IL-17 |
| T107 |
1272-1277 |
Protein |
denotes |
IL-17 |
| T152 |
1296-1305 |
Positive_regulation |
denotes |
increased |
| T153 |
1367-1371 |
Protein |
denotes |
CD28 |
| T108 |
1367-1371 |
Protein |
denotes |
CD28 |
| T154 |
1376-1379 |
Protein |
denotes |
PHA |
| T109 |
1376-1379 |
Protein |
denotes |
PHA |
| T155 |
1431-1436 |
Protein |
denotes |
IL-15 |
| T110 |
1431-1436 |
Protein |
denotes |
IL-15 |
| T156 |
1438-1472 |
Protein |
denotes |
monocyte chemoattractant protein-1 |
| T111 |
1438-1472 |
Protein |
denotes |
monocyte chemoattractant protein-1 |
| T157 |
1477-1481 |
Protein |
denotes |
IL-6 |
| T112 |
1477-1481 |
Protein |
denotes |
IL-6 |
| T158 |
1482-1493 |
Positive_regulation |
denotes |
upregulated |
| T159 |
1494-1499 |
Protein |
denotes |
IL-17 |
| T113 |
1494-1499 |
Protein |
denotes |
IL-17 |
| T160 |
1500-1510 |
Gene_expression |
denotes |
production |
| T161 |
1531-1554 |
Protein |
denotes |
tumor necrosis factor-α |
| T114 |
1531-1554 |
Protein |
denotes |
tumor necrosis factor-α |
| T162 |
1556-1561 |
Protein |
denotes |
IL-1β |
| T115 |
1556-1561 |
Protein |
denotes |
IL-1β |
| T163 |
1563-1568 |
Protein |
denotes |
IL-18 |
| T116 |
1563-1568 |
Protein |
denotes |
IL-18 |
| T164 |
1572-1600 |
Protein |
denotes |
transforming growth factor-β |
| T117 |
1572-1600 |
Protein |
denotes |
transforming growth factor-β |
| T165 |
1610-1615 |
Protein |
denotes |
IL-17 |
| T118 |
1610-1615 |
Protein |
denotes |
IL-17 |
| T166 |
1689-1699 |
Gene_expression |
denotes |
expression |
| T167 |
1783-1786 |
Protein |
denotes |
Akt |
| T119 |
1783-1786 |
Protein |
denotes |
Akt |
| T168 |
1823-1831 |
Positive_regulation |
denotes |
resulted |
| T169 |
1894-1901 |
Binding |
denotes |
binding |
| T170 |
1912-1917 |
Protein |
denotes |
IL-17 |
| T120 |
1912-1917 |
Protein |
denotes |
IL-17 |
| T171 |
1918-1928 |
Gene_expression |
denotes |
production |
| T172 |
1932-1941 |
Positive_regulation |
denotes |
activated |
| T173 |
2062-2065 |
Protein |
denotes |
Akt |
| T121 |
2062-2065 |
Protein |
denotes |
Akt |
| T174 |
2066-2075 |
Negative_regulation |
denotes |
inhibitor |
| T175 |
2124-2134 |
Negative_regulation |
denotes |
inhibition |
| T176 |
2138-2157 |
Protein |
denotes |
activator protein-1 |
| T122 |
2138-2157 |
Protein |
denotes |
activator protein-1 |
| T177 |
2162-2201 |
Protein |
denotes |
extracellular signal-regulated kinase 1 |
| T123 |
2162-2201 |
Protein |
denotes |
extracellular signal-regulated kinase 1 |
| T178 |
2202-2203 |
Protein |
denotes |
2 |
| T124 |
2202-2203 |
Protein |
denotes |
2 |
| T179 |
2212-2218 |
Regulation |
denotes |
affect |
| T180 |
2219-2224 |
Protein |
denotes |
IL-17 |
| T125 |
2219-2224 |
Protein |
denotes |
IL-17 |
| T181 |
2225-2235 |
Gene_expression |
denotes |
production |
| T182 |
2311-2314 |
Protein |
denotes |
Akt |
| T126 |
2311-2314 |
Protein |
denotes |
Akt |
| T183 |
2393-2398 |
Protein |
denotes |
IL-17 |
| T127 |
2393-2398 |
Protein |
denotes |
IL-17 |
| T2187 |
2713-2723 |
Negative_regulation |
denotes |
inhibitors |
| T2188 |
2727-2756 |
Protein |
denotes |
tumor necrosis factor (TNF)-α |
| T2154 |
2727-2756 |
Protein |
denotes |
tumor necrosis factor (TNF)-α |
| T2189 |
2762-2780 |
Protein |
denotes |
interleukin (IL)-1 |
| T2155 |
2762-2780 |
Protein |
denotes |
interleukin (IL)-1 |
| T2190 |
3199-3203 |
Protein |
denotes |
IL-2 |
| T2156 |
3199-3203 |
Protein |
denotes |
IL-2 |
| T2191 |
3208-3220 |
Protein |
denotes |
interferon-γ |
| T2157 |
3208-3220 |
Protein |
denotes |
interferon-γ |
| T2192 |
3296-3300 |
Protein |
denotes |
IL-1 |
| T2158 |
3296-3300 |
Protein |
denotes |
IL-1 |
| T2193 |
3302-3306 |
Protein |
denotes |
IL-6 |
| T2159 |
3302-3306 |
Protein |
denotes |
IL-6 |
| T2194 |
3308-3313 |
Protein |
denotes |
IL-15 |
| T2160 |
3308-3313 |
Protein |
denotes |
IL-15 |
| T2195 |
3315-3320 |
Protein |
denotes |
IL-18 |
| T2161 |
3315-3320 |
Protein |
denotes |
IL-18 |
| T2196 |
3325-3330 |
Protein |
denotes |
TNF-α |
| T2162 |
3325-3330 |
Protein |
denotes |
TNF-α |
| T2197 |
3700-3705 |
Protein |
denotes |
IL-17 |
| T2163 |
3700-3705 |
Protein |
denotes |
IL-17 |
| T2198 |
3791-3797 |
Positive_regulation |
denotes |
induce |
| T2199 |
3798-3802 |
Protein |
denotes |
IL-6 |
| T2164 |
3798-3802 |
Protein |
denotes |
IL-6 |
| T2200 |
3807-3811 |
Protein |
denotes |
IL-8 |
| T2165 |
3807-3811 |
Protein |
denotes |
IL-8 |
| T2201 |
3904-3909 |
Protein |
denotes |
TNF-α |
| T2166 |
3904-3909 |
Protein |
denotes |
TNF-α |
| T2202 |
3914-3918 |
Protein |
denotes |
IL-1 |
| T2167 |
3914-3918 |
Protein |
denotes |
IL-1 |
| T2203 |
3920-3925 |
Protein |
denotes |
IL-17 |
| T2168 |
3920-3925 |
Protein |
denotes |
IL-17 |
| T2204 |
3972-3980 |
Gene_expression |
denotes |
produced |
| T2205 |
4035-4040 |
Protein |
denotes |
IL-17 |
| T2169 |
4035-4040 |
Protein |
denotes |
IL-17 |
| T2206 |
4095-4104 |
Positive_regulation |
denotes |
induction |
| T2207 |
4108-4113 |
Protein |
denotes |
RANKL |
| T2170 |
4108-4113 |
Protein |
denotes |
RANKL |
| T2208 |
4115-4169 |
Protein |
denotes |
receptor activator of nuclear factor κB [NF-κB] ligand |
| T2171 |
4115-4169 |
Protein |
denotes |
receptor activator of nuclear factor κB [NF-κB] ligand |
| T2209 |
4225-4235 |
Positive_regulation |
denotes |
stimulates |
| T2210 |
4240-4250 |
Gene_expression |
denotes |
production |
| T2211 |
4254-4258 |
Protein |
denotes |
IL-6 |
| T2172 |
4254-4258 |
Protein |
denotes |
IL-6 |
| T2212 |
4263-4289 |
Protein |
denotes |
leukemia inhibitory factor |
| T2173 |
4263-4289 |
Protein |
denotes |
leukemia inhibitory factor |
| T2213 |
4453-4458 |
Protein |
denotes |
IL-17 |
| T2174 |
4453-4458 |
Protein |
denotes |
IL-17 |
| T2214 |
4578-4586 |
Gene_expression |
denotes |
produced |
| T2215 |
4590-4593 |
Protein |
denotes |
CD4 |
| T2175 |
4590-4593 |
Protein |
denotes |
CD4 |
| T2216 |
4628-4633 |
Protein |
denotes |
IL-15 |
| T2176 |
4628-4633 |
Protein |
denotes |
IL-15 |
| T2217 |
4709-4716 |
Positive_regulation |
denotes |
trigger |
| T2218 |
4720-4725 |
Protein |
denotes |
IL-17 |
| T2177 |
4720-4725 |
Protein |
denotes |
IL-17 |
| T2219 |
4726-4736 |
Gene_expression |
denotes |
production |
| T2220 |
4887-4892 |
Protein |
denotes |
IL-23 |
| T2178 |
4887-4892 |
Protein |
denotes |
IL-23 |
| T2221 |
4915-4922 |
Positive_regulation |
denotes |
trigger |
| T2222 |
4926-4931 |
Protein |
denotes |
IL-17 |
| T2179 |
4926-4931 |
Protein |
denotes |
IL-17 |
| T2223 |
4932-4942 |
Gene_expression |
denotes |
production |
| T2224 |
4953-4956 |
Protein |
denotes |
CD4 |
| T2180 |
4953-4956 |
Protein |
denotes |
CD4 |
| T2225 |
4962-4965 |
Protein |
denotes |
CD8 |
| T2181 |
4962-4965 |
Protein |
denotes |
CD8 |
| T2226 |
5010-5015 |
Protein |
denotes |
IL-17 |
| T2182 |
5010-5015 |
Protein |
denotes |
IL-17 |
| T2227 |
5145-5150 |
Protein |
denotes |
IL-17 |
| T2183 |
5145-5150 |
Protein |
denotes |
IL-17 |
| T2228 |
5151-5161 |
Gene_expression |
denotes |
production |
| T2184 |
5241-5246 |
Protein |
denotes |
IL-17 |
| T2229 |
5241-5246 |
Protein |
denotes |
IL-17 |
| T2230 |
5247-5257 |
Gene_expression |
denotes |
production |
| T2185 |
5419-5422 |
Protein |
denotes |
Akt |
| T2231 |
5419-5422 |
Protein |
denotes |
Akt |
| T2186 |
5506-5511 |
Protein |
denotes |
IL-17 |
| T2232 |
5506-5511 |
Protein |
denotes |
IL-17 |
| T5254 |
6478-6483 |
Protein |
denotes |
IL-17 |
| T5239 |
6478-6483 |
Protein |
denotes |
IL-17 |
| T5255 |
6485-6490 |
Protein |
denotes |
IL-18 |
| T5240 |
6485-6490 |
Protein |
denotes |
IL-18 |
| T5256 |
6492-6497 |
Protein |
denotes |
IL-15 |
| T5241 |
6492-6497 |
Protein |
denotes |
IL-15 |
| T5257 |
6499-6533 |
Protein |
denotes |
monocyte chemoattractant protein-1 |
| T5242 |
6499-6533 |
Protein |
denotes |
monocyte chemoattractant protein-1 |
| T5258 |
6535-6540 |
Protein |
denotes |
MCP-1 |
| T5243 |
6535-6540 |
Protein |
denotes |
MCP-1 |
| T5259 |
6543-6583 |
Protein |
denotes |
macrophage inflammatory protein (MIP)-1α |
| T5244 |
6543-6583 |
Protein |
denotes |
macrophage inflammatory protein (MIP)-1α |
| T5260 |
6585-6591 |
Protein |
denotes |
MIP-1β |
| T5245 |
6585-6591 |
Protein |
denotes |
MIP-1β |
| T5261 |
6593-6597 |
Protein |
denotes |
IL-6 |
| T5246 |
6593-6597 |
Protein |
denotes |
IL-6 |
| T5247 |
6602-6606 |
Protein |
denotes |
IL-8 |
| T5262 |
6602-6606 |
Protein |
denotes |
IL-8 |
| T5248 |
6677-6711 |
Protein |
denotes |
transforming growth factor (TGF)-β |
| T5263 |
6677-6711 |
Protein |
denotes |
transforming growth factor (TGF)-β |
| T5249 |
6767-6772 |
Protein |
denotes |
TNF-α |
| T5264 |
6767-6772 |
Protein |
denotes |
TNF-α |
| T5250 |
6777-6781 |
Protein |
denotes |
IL-1 |
| T5265 |
6777-6781 |
Protein |
denotes |
IL-1 |
| T5266 |
6901-6919 |
Protein |
denotes |
Phytohemagglutinin |
| T5251 |
6901-6919 |
Protein |
denotes |
Phytohemagglutinin |
| T5267 |
6921-6924 |
Protein |
denotes |
PHA |
| T5252 |
6921-6924 |
Protein |
denotes |
PHA |
| T5268 |
7106-7110 |
Protein |
denotes |
CD28 |
| T5253 |
7106-7110 |
Protein |
denotes |
CD28 |
| T5914 |
7291-7301 |
Gene_expression |
denotes |
Production |
| T5915 |
7305-7310 |
Protein |
denotes |
IL-17 |
| T5913 |
7305-7310 |
Protein |
denotes |
IL-17 |
| T6534 |
8322-8325 |
Protein |
denotes |
CD4 |
| T6529 |
8322-8325 |
Protein |
denotes |
CD4 |
| T6535 |
8357-8360 |
Protein |
denotes |
CD4 |
| T6530 |
8357-8360 |
Protein |
denotes |
CD4 |
| T6536 |
8506-8509 |
Protein |
denotes |
CD4 |
| T6531 |
8506-8509 |
Protein |
denotes |
CD4 |
| T6537 |
9052-9055 |
Protein |
denotes |
CD4 |
| T6532 |
9052-9055 |
Protein |
denotes |
CD4 |
| T6538 |
9400-9403 |
Protein |
denotes |
CD4 |
| T6533 |
9400-9403 |
Protein |
denotes |
CD4 |
| T7245 |
9457-9462 |
Protein |
denotes |
IL-17 |
| T7253 |
9463-9468 |
Protein |
denotes |
IL-17 |
| T7246 |
9463-9468 |
Protein |
denotes |
IL-17 |
| T7254 |
9669-9674 |
Protein |
denotes |
IL-17 |
| T7247 |
9669-9674 |
Protein |
denotes |
IL-17 |
| T7255 |
9885-9890 |
Protein |
denotes |
IL-17 |
| T7248 |
9885-9890 |
Protein |
denotes |
IL-17 |
| T7256 |
10140-10145 |
Protein |
denotes |
IL-17 |
| T7249 |
10140-10145 |
Protein |
denotes |
IL-17 |
| T7257 |
10583-10588 |
Protein |
denotes |
IL-17 |
| T7250 |
10583-10588 |
Protein |
denotes |
IL-17 |
| T7258 |
10631-10636 |
Protein |
denotes |
IL-17 |
| T7251 |
10631-10636 |
Protein |
denotes |
IL-17 |
| T7259 |
10878-10883 |
Protein |
denotes |
IL-17 |
| T7252 |
10878-10883 |
Protein |
denotes |
IL-17 |
| T8206 |
10920-10925 |
Protein |
denotes |
IL-17 |
| T8194 |
10920-10925 |
Protein |
denotes |
IL-17 |
| T8207 |
11497-11500 |
Protein |
denotes |
Taq |
| T8195 |
11497-11500 |
Protein |
denotes |
Taq |
| T8208 |
11760-11765 |
Protein |
denotes |
IL-17 |
| T8196 |
11760-11765 |
Protein |
denotes |
IL-17 |
| T8209 |
11868-11908 |
Protein |
denotes |
glyceraldehyde-3-phosphate dehydrogenase |
| T8197 |
11868-11908 |
Protein |
denotes |
glyceraldehyde-3-phosphate dehydrogenase |
| T8210 |
11910-11915 |
Protein |
denotes |
GAPDH |
| T8198 |
11910-11915 |
Protein |
denotes |
GAPDH |
| T8211 |
11957-11962 |
Protein |
denotes |
GAPDH |
| T8199 |
11957-11962 |
Protein |
denotes |
GAPDH |
| T8212 |
12176-12181 |
Protein |
denotes |
GAPDH |
| T8200 |
12176-12181 |
Protein |
denotes |
GAPDH |
| T8213 |
12186-12191 |
Protein |
denotes |
IL-17 |
| T8201 |
12186-12191 |
Protein |
denotes |
IL-17 |
| T8214 |
12287-12292 |
Protein |
denotes |
GAPDH |
| T8202 |
12287-12292 |
Protein |
denotes |
GAPDH |
| T8215 |
12297-12302 |
Protein |
denotes |
IL-17 |
| T8203 |
12297-12302 |
Protein |
denotes |
IL-17 |
| T8216 |
12413-12428 |
Transcription |
denotes |
mRNA expression |
| T8217 |
12457-12462 |
Protein |
denotes |
IL-17 |
| T8204 |
12457-12462 |
Protein |
denotes |
IL-17 |
| T8218 |
12480-12485 |
Protein |
denotes |
GAPDH |
| T8205 |
12480-12485 |
Protein |
denotes |
GAPDH |
| T9211 |
12521-12524 |
Protein |
denotes |
Akt |
| T9205 |
12521-12524 |
Protein |
denotes |
Akt |
| T9212 |
12526-12540 |
Phosphorylation |
denotes |
phosphorylated |
| T9213 |
12541-12544 |
Protein |
denotes |
Akt |
| T9206 |
12541-12544 |
Protein |
denotes |
Akt |
| T9207 |
12549-12554 |
Protein |
denotes |
IκB-α |
| T9214 |
13276-13279 |
Protein |
denotes |
Akt |
| T9208 |
13276-13279 |
Protein |
denotes |
Akt |
| T9215 |
13281-13295 |
Phosphorylation |
denotes |
phosphorylated |
| T9216 |
13296-13299 |
Protein |
denotes |
Akt |
| T9209 |
13296-13299 |
Protein |
denotes |
Akt |
| T9217 |
13304-13309 |
Protein |
denotes |
IκB-α |
| T9210 |
13304-13309 |
Protein |
denotes |
IκB-α |
| T9986 |
13930-13935 |
Protein |
denotes |
IL-17 |
| T9982 |
13930-13935 |
Protein |
denotes |
IL-17 |
| T9987 |
14824-14827 |
Protein |
denotes |
p50 |
| T9983 |
14824-14827 |
Protein |
denotes |
p50 |
| T9988 |
14829-14832 |
Protein |
denotes |
p65 |
| T9984 |
14829-14832 |
Protein |
denotes |
p65 |
| T9989 |
14837-14842 |
Protein |
denotes |
c-Rel |
| T9985 |
14837-14842 |
Protein |
denotes |
c-Rel |
| T11101 |
15493-15498 |
Protein |
denotes |
IL-17 |
| T11095 |
15493-15498 |
Protein |
denotes |
IL-17 |
| T11102 |
15499-15509 |
Gene_expression |
denotes |
production |
| T11103 |
15619-15622 |
Protein |
denotes |
PHA |
| T11096 |
15619-15622 |
Protein |
denotes |
PHA |
| T11104 |
15707-15712 |
Protein |
denotes |
IL-17 |
| T11097 |
15707-15712 |
Protein |
denotes |
IL-17 |
| T11105 |
15809-15814 |
Protein |
denotes |
IL-17 |
| T11098 |
15809-15814 |
Protein |
denotes |
IL-17 |
| T11106 |
15815-15824 |
Localization |
denotes |
secretion |
| T11107 |
15935-15940 |
Protein |
denotes |
IL-17 |
| T11099 |
15935-15940 |
Protein |
denotes |
IL-17 |
| T11108 |
15941-15951 |
Gene_expression |
denotes |
production |
| T11109 |
15952-15962 |
Positive_regulation |
denotes |
stimulated |
| T11110 |
15966-15969 |
Protein |
denotes |
PHA |
| T11100 |
15966-15969 |
Protein |
denotes |
PHA |
| T11111 |
15988-15994 |
Positive_regulation |
denotes |
higher |
| T11657 |
16120-16129 |
Positive_regulation |
denotes |
Increased |
| T11658 |
16130-16135 |
Protein |
denotes |
IL-17 |
| T11646 |
16130-16135 |
Protein |
denotes |
IL-17 |
| T11659 |
16136-16146 |
Gene_expression |
denotes |
production |
| T11660 |
16199-16203 |
Protein |
denotes |
CD28 |
| T11647 |
16199-16203 |
Protein |
denotes |
CD28 |
| T11661 |
16209-16212 |
Protein |
denotes |
PHA |
| T11648 |
16209-16212 |
Protein |
denotes |
PHA |
| T11662 |
16221-16226 |
Protein |
denotes |
IL-17 |
| T11649 |
16221-16226 |
Protein |
denotes |
IL-17 |
| T11663 |
16272-16280 |
Gene_expression |
denotes |
produced |
| T11664 |
16441-16450 |
Regulation |
denotes |
dependent |
| T11665 |
16451-16459 |
Positive_regulation |
denotes |
increase |
| T11666 |
16463-16468 |
Protein |
denotes |
IL-17 |
| T11650 |
16463-16468 |
Protein |
denotes |
IL-17 |
| T11667 |
16623-16634 |
Positive_regulation |
denotes |
upregulated |
| T11668 |
16635-16640 |
Protein |
denotes |
IL-17 |
| T11651 |
16635-16640 |
Protein |
denotes |
IL-17 |
| T11669 |
16641-16651 |
Gene_expression |
denotes |
production |
| T11670 |
16696-16700 |
Protein |
denotes |
CD28 |
| T11652 |
16696-16700 |
Protein |
denotes |
CD28 |
| T11671 |
16714-16722 |
Gene_expression |
denotes |
produced |
| T11672 |
16728-16733 |
Protein |
denotes |
IL-17 |
| T11653 |
16728-16733 |
Protein |
denotes |
IL-17 |
| T11673 |
16841-16844 |
Protein |
denotes |
PHA |
| T11654 |
16841-16844 |
Protein |
denotes |
PHA |
| T11674 |
16846-16855 |
Positive_regulation |
denotes |
increased |
| T11675 |
16856-16861 |
Protein |
denotes |
IL-17 |
| T11655 |
16856-16861 |
Protein |
denotes |
IL-17 |
| T11676 |
16862-16872 |
Gene_expression |
denotes |
production |
| T11677 |
16921-16925 |
Protein |
denotes |
CD28 |
| T11656 |
16921-16925 |
Protein |
denotes |
CD28 |
| T12424 |
16970-16980 |
Regulation |
denotes |
Regulation |
| T12425 |
16984-16989 |
Protein |
denotes |
IL-17 |
| T12408 |
16984-16989 |
Protein |
denotes |
IL-17 |
| T12426 |
16990-17000 |
Gene_expression |
denotes |
production |
| T12427 |
17207-17215 |
Regulation |
denotes |
affected |
| T12428 |
17220-17230 |
Gene_expression |
denotes |
production |
| T12429 |
17234-17239 |
Protein |
denotes |
IL-17 |
| T12409 |
17234-17239 |
Protein |
denotes |
IL-17 |
| T12430 |
17393-17398 |
Protein |
denotes |
IL-17 |
| T12410 |
17393-17398 |
Protein |
denotes |
IL-17 |
| T12431 |
17399-17409 |
Gene_expression |
denotes |
production |
| T12432 |
17426-17434 |
Positive_regulation |
denotes |
increase |
| T12433 |
17438-17443 |
Protein |
denotes |
IL-17 |
| T12411 |
17438-17443 |
Protein |
denotes |
IL-17 |
| T12434 |
17473-17478 |
Protein |
denotes |
IL-15 |
| T12412 |
17473-17478 |
Protein |
denotes |
IL-15 |
| T12435 |
17504-17509 |
Protein |
denotes |
IL-1β |
| T12413 |
17504-17509 |
Protein |
denotes |
IL-1β |
| T12436 |
17522-17527 |
Protein |
denotes |
TNF-α |
| T12414 |
17522-17527 |
Protein |
denotes |
TNF-α |
| T12437 |
17540-17545 |
Protein |
denotes |
IL-18 |
| T12415 |
17540-17545 |
Protein |
denotes |
IL-18 |
| T12438 |
17560-17565 |
Protein |
denotes |
TGF-β |
| T12416 |
17560-17565 |
Protein |
denotes |
TGF-β |
| T12439 |
17591-17596 |
Protein |
denotes |
IL-17 |
| T12417 |
17591-17596 |
Protein |
denotes |
IL-17 |
| T12440 |
17641-17646 |
Protein |
denotes |
MCP-1 |
| T12418 |
17641-17646 |
Protein |
denotes |
MCP-1 |
| T12441 |
17661-17665 |
Protein |
denotes |
IL-6 |
| T12419 |
17661-17665 |
Protein |
denotes |
IL-6 |
| T12442 |
17707-17712 |
Protein |
denotes |
IL-17 |
| T12420 |
17707-17712 |
Protein |
denotes |
IL-17 |
| T12443 |
17835-17839 |
Protein |
denotes |
IL-8 |
| T12421 |
17835-17839 |
Protein |
denotes |
IL-8 |
| T12444 |
17852-17858 |
Protein |
denotes |
MIP-1α |
| T12422 |
17852-17858 |
Protein |
denotes |
MIP-1α |
| T12445 |
17873-17879 |
Protein |
denotes |
MIP-1β |
| T12423 |
17873-17879 |
Protein |
denotes |
MIP-1β |
| T13339 |
17903-17913 |
Negative_regulation |
denotes |
Inhibition |
| T13340 |
17917-17922 |
Protein |
denotes |
IL-17 |
| T13330 |
17917-17922 |
Protein |
denotes |
IL-17 |
| T13341 |
17923-17933 |
Gene_expression |
denotes |
production |
| T13342 |
18013-18022 |
Positive_regulation |
denotes |
increased |
| T13343 |
18023-18028 |
Protein |
denotes |
IL-17 |
| T13331 |
18023-18028 |
Protein |
denotes |
IL-17 |
| T13344 |
18029-18039 |
Gene_expression |
denotes |
production |
| T13345 |
18168-18176 |
Negative_regulation |
denotes |
decrease |
| T13346 |
18189-18196 |
Positive_regulation |
denotes |
induced |
| T13347 |
18197-18202 |
Protein |
denotes |
IL-17 |
| T13332 |
18197-18202 |
Protein |
denotes |
IL-17 |
| T13348 |
18203-18213 |
Gene_expression |
denotes |
production |
| T13349 |
18455-18464 |
Negative_regulation |
denotes |
inhibited |
| T13350 |
18478-18485 |
Positive_regulation |
denotes |
induced |
| T13351 |
18486-18491 |
Protein |
denotes |
IL-17 |
| T13333 |
18486-18491 |
Protein |
denotes |
IL-17 |
| T13352 |
18492-18502 |
Gene_expression |
denotes |
production |
| T13353 |
18604-18615 |
Protein |
denotes |
calcineurin |
| T13334 |
18604-18615 |
Protein |
denotes |
calcineurin |
| T13354 |
18656-18669 |
Negative_regulation |
denotes |
downregulated |
| T13355 |
18674-18679 |
Protein |
denotes |
IL-17 |
| T13335 |
18674-18679 |
Protein |
denotes |
IL-17 |
| T13356 |
18680-18689 |
Localization |
denotes |
secretion |
| T13357 |
18810-18816 |
Regulation |
denotes |
effect |
| T13358 |
18820-18825 |
Protein |
denotes |
IL-17 |
| T13336 |
18820-18825 |
Protein |
denotes |
IL-17 |
| T13359 |
18993-19003 |
Negative_regulation |
denotes |
inhibition |
| T13360 |
19007-19012 |
Protein |
denotes |
IL-17 |
| T13337 |
19007-19012 |
Protein |
denotes |
IL-17 |
| T13361 |
19013-19023 |
Gene_expression |
denotes |
production |
| T13362 |
19049-19058 |
Regulation |
denotes |
dependent |
| T13363 |
19059-19070 |
Negative_regulation |
denotes |
inhibitions |
| T13364 |
19074-19079 |
Protein |
denotes |
IL-17 |
| T13338 |
19074-19079 |
Protein |
denotes |
IL-17 |
| T13365 |
19080-19090 |
Gene_expression |
denotes |
production |
| T14424 |
19334-19339 |
Protein |
denotes |
IL-17 |
| T14421 |
19334-19339 |
Protein |
denotes |
IL-17 |
| T14425 |
19340-19355 |
Transcription |
denotes |
mRNA expression |
| T14426 |
19382-19390 |
Positive_regulation |
denotes |
enhanced |
| T14427 |
19391-19396 |
Protein |
denotes |
IL-17 |
| T14422 |
19391-19396 |
Protein |
denotes |
IL-17 |
| T14428 |
19397-19407 |
Gene_expression |
denotes |
production |
| T14429 |
19417-19426 |
Regulation |
denotes |
regulated |
| T14430 |
19555-19564 |
Regulation |
denotes |
dependent |
| T14431 |
19565-19573 |
Positive_regulation |
denotes |
increase |
| T14432 |
19577-19582 |
Protein |
denotes |
IL-17 |
| T14423 |
19577-19582 |
Protein |
denotes |
IL-17 |
| T14433 |
19583-19587 |
Transcription |
denotes |
mRNA |
| T14434 |
19588-19599 |
Transcription |
denotes |
transcripts |
| T14435 |
19642-19651 |
Negative_regulation |
denotes |
inhibited |
| T14436 |
19664-19673 |
Negative_regulation |
denotes |
inhibitor |
| T14748 |
19745-19748 |
Protein |
denotes |
Akt |
| T14738 |
19745-19748 |
Protein |
denotes |
Akt |
| T14749 |
19780-19785 |
Protein |
denotes |
IL-17 |
| T14739 |
19780-19785 |
Protein |
denotes |
IL-17 |
| T14750 |
19786-19796 |
Gene_expression |
denotes |
production |
| T14751 |
19890-19900 |
Positive_regulation |
denotes |
activation |
| T14740 |
19904-19907 |
Protein |
denotes |
Akt |
| T14752 |
19904-19907 |
Protein |
denotes |
Akt |
| T14753 |
20051-20065 |
Phosphorylation |
denotes |
phosphorylated |
| T14741 |
20066-20069 |
Protein |
denotes |
Akt |
| T14754 |
20066-20069 |
Protein |
denotes |
Akt |
| T14755 |
20121-20135 |
Phosphorylation |
denotes |
phosphorylated |
| T14742 |
20136-20139 |
Protein |
denotes |
Akt |
| T14756 |
20136-20139 |
Protein |
denotes |
Akt |
| T14757 |
20140-20149 |
Positive_regulation |
denotes |
increased |
| T14758 |
20277-20291 |
Phosphorylation |
denotes |
phosphorylated |
| T14743 |
20292-20295 |
Protein |
denotes |
Akt |
| T14759 |
20292-20295 |
Protein |
denotes |
Akt |
| T14744 |
20300-20307 |
Protein |
denotes |
β-actin |
| T14760 |
20300-20307 |
Protein |
denotes |
β-actin |
| T14745 |
20358-20361 |
Protein |
denotes |
PHA |
| T14761 |
20358-20361 |
Protein |
denotes |
PHA |
| T14746 |
20382-20387 |
Protein |
denotes |
IL-15 |
| T14762 |
20382-20387 |
Protein |
denotes |
IL-15 |
| T14763 |
20415-20421 |
Regulation |
denotes |
effect |
| T14764 |
20425-20439 |
Phosphorylation |
denotes |
phosphorylated |
| T14747 |
20440-20443 |
Protein |
denotes |
Akt |
| T14765 |
20440-20443 |
Protein |
denotes |
Akt |
| T14766 |
20481-20491 |
Negative_regulation |
denotes |
inhibition |
| T15552 |
20585-20604 |
Protein |
denotes |
activator protein-1 |
| T15532 |
20585-20604 |
Protein |
denotes |
activator protein-1 |
| T15553 |
20606-20610 |
Protein |
denotes |
AP-1 |
| T15533 |
20606-20610 |
Protein |
denotes |
AP-1 |
| T15554 |
20627-20632 |
Protein |
denotes |
IL-17 |
| T15534 |
20627-20632 |
Protein |
denotes |
IL-17 |
| T15555 |
20740-20744 |
Protein |
denotes |
CD28 |
| T15535 |
20740-20744 |
Protein |
denotes |
CD28 |
| T15556 |
20762-20765 |
Protein |
denotes |
PHA |
| T15536 |
20762-20765 |
Protein |
denotes |
PHA |
| T15557 |
20770-20775 |
Protein |
denotes |
IL-15 |
| T15537 |
20770-20775 |
Protein |
denotes |
IL-15 |
| T15558 |
20797-20805 |
Negative_regulation |
denotes |
inducing |
| T15559 |
20806-20811 |
Protein |
denotes |
IL-17 |
| T15538 |
20806-20811 |
Protein |
denotes |
IL-17 |
| T15560 |
20812-20822 |
Gene_expression |
denotes |
expression |
| T15561 |
20931-20936 |
Protein |
denotes |
IL-17 |
| T15539 |
20931-20936 |
Protein |
denotes |
IL-17 |
| T15562 |
21024-21028 |
Protein |
denotes |
CD28 |
| T15540 |
21024-21028 |
Protein |
denotes |
CD28 |
| T15563 |
21051-21060 |
Positive_regulation |
denotes |
increased |
| T15564 |
21061-21068 |
Binding |
denotes |
binding |
| T15565 |
21081-21086 |
Protein |
denotes |
IL-17 |
| T15541 |
21081-21086 |
Protein |
denotes |
IL-17 |
| T15566 |
21192-21195 |
Protein |
denotes |
p65 |
| T15542 |
21192-21195 |
Protein |
denotes |
p65 |
| T15567 |
21200-21203 |
Protein |
denotes |
p50 |
| T15543 |
21200-21203 |
Protein |
denotes |
p50 |
| T15568 |
21227-21232 |
Protein |
denotes |
c-Rel |
| T15544 |
21227-21232 |
Protein |
denotes |
c-Rel |
| T15569 |
21346-21350 |
Protein |
denotes |
CD28 |
| T15545 |
21346-21350 |
Protein |
denotes |
CD28 |
| T15570 |
21568-21573 |
Negative_regulation |
denotes |
block |
| T15571 |
21584-21591 |
Binding |
denotes |
binding |
| T15572 |
21608-21613 |
Protein |
denotes |
IL-17 |
| T15546 |
21608-21613 |
Protein |
denotes |
IL-17 |
| T15573 |
21655-21660 |
Protein |
denotes |
IκB-α |
| T15547 |
21655-21660 |
Protein |
denotes |
IκB-α |
| T15574 |
21668-21678 |
Negative_regulation |
denotes |
inhibition |
| T15575 |
21682-21693 |
Protein_catabolism |
denotes |
degradation |
| T15576 |
21697-21702 |
Protein |
denotes |
IκB-α |
| T15548 |
21697-21702 |
Protein |
denotes |
IκB-α |
| T15577 |
21769-21773 |
Protein |
denotes |
AP-1 |
| T15549 |
21769-21773 |
Protein |
denotes |
AP-1 |
| T15578 |
21839-21843 |
Protein |
denotes |
CD28 |
| T15550 |
21839-21843 |
Protein |
denotes |
CD28 |
| T15579 |
21934-21939 |
Protein |
denotes |
IL-17 |
| T15551 |
21934-21939 |
Protein |
denotes |
IL-17 |
| T15580 |
21940-21950 |
Gene_expression |
denotes |
production |
| T15581 |
21954-21963 |
Positive_regulation |
denotes |
activated |
| T17096 |
22004-22009 |
Protein |
denotes |
IL-17 |
| T17027 |
22004-22009 |
Protein |
denotes |
IL-17 |
| T17097 |
22239-22243 |
Protein |
denotes |
IL-1 |
| T17028 |
22239-22243 |
Protein |
denotes |
IL-1 |
| T17098 |
22248-22253 |
Protein |
denotes |
TNF-α |
| T17029 |
22248-22253 |
Protein |
denotes |
TNF-α |
| T17099 |
22340-22344 |
Protein |
denotes |
IL-4 |
| T17030 |
22340-22344 |
Protein |
denotes |
IL-4 |
| T17100 |
22349-22361 |
Protein |
denotes |
interferon-γ |
| T17031 |
22349-22361 |
Protein |
denotes |
interferon-γ |
| T17101 |
22594-22599 |
Protein |
denotes |
IL-17 |
| T17032 |
22594-22599 |
Protein |
denotes |
IL-17 |
| T17102 |
22746-22751 |
Protein |
denotes |
IL-17 |
| T17033 |
22746-22751 |
Protein |
denotes |
IL-17 |
| T17103 |
22752-22762 |
Gene_expression |
denotes |
production |
| T17104 |
22766-22775 |
Regulation |
denotes |
regulated |
| T17105 |
22835-22840 |
Protein |
denotes |
IL-17 |
| T17034 |
22835-22840 |
Protein |
denotes |
IL-17 |
| T17106 |
22975-22984 |
Positive_regulation |
denotes |
stimulate |
| T17107 |
22985-22990 |
Protein |
denotes |
IL-17 |
| T17035 |
22985-22990 |
Protein |
denotes |
IL-17 |
| T17108 |
22991-23001 |
Gene_expression |
denotes |
production |
| T17109 |
23039-23044 |
Protein |
denotes |
IL-17 |
| T17036 |
23039-23044 |
Protein |
denotes |
IL-17 |
| T17110 |
23045-23055 |
Gene_expression |
denotes |
production |
| T17111 |
23089-23093 |
Protein |
denotes |
CD28 |
| T17037 |
23089-23093 |
Protein |
denotes |
CD28 |
| T17112 |
23155-23158 |
Protein |
denotes |
PHA |
| T17038 |
23155-23158 |
Protein |
denotes |
PHA |
| T17113 |
23197-23201 |
Protein |
denotes |
CD28 |
| T17039 |
23197-23201 |
Protein |
denotes |
CD28 |
| T17114 |
23245-23254 |
Positive_regulation |
denotes |
increased |
| T17115 |
23255-23260 |
Protein |
denotes |
IL-17 |
| T17040 |
23255-23260 |
Protein |
denotes |
IL-17 |
| T17116 |
23261-23271 |
Gene_expression |
denotes |
production |
| T17117 |
23295-23304 |
Regulation |
denotes |
dependent |
| T17118 |
23381-23393 |
Positive_regulation |
denotes |
upregulation |
| T17119 |
23397-23402 |
Protein |
denotes |
IL-17 |
| T17041 |
23397-23402 |
Protein |
denotes |
IL-17 |
| T17120 |
23412-23415 |
Positive_regulation |
denotes |
due |
| T17121 |
23486-23491 |
Protein |
denotes |
IL-17 |
| T17042 |
23486-23491 |
Protein |
denotes |
IL-17 |
| T17122 |
23495-23503 |
Gene_expression |
denotes |
produced |
| T17123 |
23524-23527 |
Protein |
denotes |
CD4 |
| T17043 |
23524-23527 |
Protein |
denotes |
CD4 |
| T17124 |
23620-23628 |
Gene_expression |
denotes |
produced |
| T17125 |
23632-23635 |
Protein |
denotes |
CD8 |
| T17044 |
23632-23635 |
Protein |
denotes |
CD8 |
| T17126 |
23652-23657 |
Protein |
denotes |
IL-23 |
| T17045 |
23652-23657 |
Protein |
denotes |
IL-23 |
| T17127 |
23735-23740 |
Protein |
denotes |
IL-17 |
| T17046 |
23735-23740 |
Protein |
denotes |
IL-17 |
| T17128 |
23741-23751 |
Gene_expression |
denotes |
production |
| T17129 |
23770-23779 |
Positive_regulation |
denotes |
augmented |
| T17130 |
24051-24056 |
Protein |
denotes |
IL-17 |
| T17047 |
24051-24056 |
Protein |
denotes |
IL-17 |
| T17048 |
24129-24133 |
Protein |
denotes |
IL-6 |
| T17131 |
24129-24133 |
Protein |
denotes |
IL-6 |
| T17049 |
24135-24139 |
Protein |
denotes |
IL-8 |
| T17132 |
24135-24139 |
Protein |
denotes |
IL-8 |
| T17050 |
24144-24183 |
Protein |
denotes |
tumor necrosis factor-stimulated gene 6 |
| T17133 |
24144-24183 |
Protein |
denotes |
tumor necrosis factor-stimulated gene 6 |
| T17134 |
24288-24297 |
Positive_regulation |
denotes |
stimulate |
| T17051 |
24298-24303 |
Protein |
denotes |
IL-17 |
| T17135 |
24298-24303 |
Protein |
denotes |
IL-17 |
| T17136 |
24304-24314 |
Gene_expression |
denotes |
production |
| T17052 |
24347-24352 |
Protein |
denotes |
IL-15 |
| T17137 |
24347-24352 |
Protein |
denotes |
IL-15 |
| T17053 |
24357-24362 |
Protein |
denotes |
IL-23 |
| T17138 |
24357-24362 |
Protein |
denotes |
IL-23 |
| T17139 |
24383-24391 |
Regulation |
denotes |
regulate |
| T17140 |
24392-24397 |
Protein |
denotes |
IL-17 |
| T17054 |
24392-24397 |
Protein |
denotes |
IL-17 |
| T17141 |
24398-24408 |
Gene_expression |
denotes |
production |
| T17142 |
24457-24467 |
Gene_expression |
denotes |
production |
| T17143 |
24471-24476 |
Protein |
denotes |
IL-17 |
| T17055 |
24471-24476 |
Protein |
denotes |
IL-17 |
| T17144 |
24611-24615 |
Protein |
denotes |
CD28 |
| T17056 |
24611-24615 |
Protein |
denotes |
CD28 |
| T17145 |
24647-24652 |
Protein |
denotes |
IL-15 |
| T17057 |
24647-24652 |
Protein |
denotes |
IL-15 |
| T17146 |
24657-24662 |
Protein |
denotes |
MCP-1 |
| T17058 |
24657-24662 |
Protein |
denotes |
MCP-1 |
| T17147 |
24701-24710 |
Positive_regulation |
denotes |
increased |
| T17148 |
24715-24725 |
Gene_expression |
denotes |
production |
| T17149 |
24729-24734 |
Protein |
denotes |
IL-17 |
| T17059 |
24729-24734 |
Protein |
denotes |
IL-17 |
| T17150 |
24754-24759 |
Protein |
denotes |
IL-15 |
| T17060 |
24754-24759 |
Protein |
denotes |
IL-15 |
| T17151 |
24763-24768 |
Protein |
denotes |
MCP-1 |
| T17061 |
24763-24768 |
Protein |
denotes |
MCP-1 |
| T17152 |
24785-24794 |
Positive_regulation |
denotes |
augmented |
| T17153 |
24795-24800 |
Protein |
denotes |
IL-17 |
| T17062 |
24795-24800 |
Protein |
denotes |
IL-17 |
| T17154 |
24801-24811 |
Gene_expression |
denotes |
production |
| T17155 |
24840-24844 |
Protein |
denotes |
IL-1 |
| T17063 |
24840-24844 |
Protein |
denotes |
IL-1 |
| T17156 |
24849-24854 |
Protein |
denotes |
TNF-α |
| T17064 |
24849-24854 |
Protein |
denotes |
TNF-α |
| T17157 |
24917-24926 |
Positive_regulation |
denotes |
increased |
| T17158 |
24949-24955 |
Regulation |
denotes |
affect |
| T17159 |
24956-24961 |
Protein |
denotes |
IL-17 |
| T17065 |
24956-24961 |
Protein |
denotes |
IL-17 |
| T17160 |
24962-24972 |
Gene_expression |
denotes |
production |
| T17161 |
25025-25030 |
Protein |
denotes |
IL-15 |
| T17066 |
25025-25030 |
Protein |
denotes |
IL-15 |
| T17162 |
25031-25040 |
Positive_regulation |
denotes |
triggered |
| T17163 |
25050-25055 |
Protein |
denotes |
IL-17 |
| T17067 |
25050-25055 |
Protein |
denotes |
IL-17 |
| T17164 |
25056-25066 |
Gene_expression |
denotes |
production |
| T17165 |
25080-25085 |
Protein |
denotes |
TNF-α |
| T17068 |
25080-25085 |
Protein |
denotes |
TNF-α |
| T17166 |
25139-25144 |
Protein |
denotes |
MCP-1 |
| T17069 |
25139-25144 |
Protein |
denotes |
MCP-1 |
| T17167 |
25373-25377 |
Protein |
denotes |
CD28 |
| T17070 |
25373-25377 |
Protein |
denotes |
CD28 |
| T17168 |
25383-25392 |
Positive_regulation |
denotes |
increases |
| T17169 |
25393-25398 |
Protein |
denotes |
IL-17 |
| T17071 |
25393-25398 |
Protein |
denotes |
IL-17 |
| T17170 |
25399-25408 |
Positive_regulation |
denotes |
induction |
| T17171 |
25497-25502 |
Protein |
denotes |
IL-17 |
| T17072 |
25497-25502 |
Protein |
denotes |
IL-17 |
| T17172 |
25576-25581 |
Protein |
denotes |
IL-17 |
| T17073 |
25576-25581 |
Protein |
denotes |
IL-17 |
| T17173 |
25582-25592 |
Gene_expression |
denotes |
production |
| T17174 |
25600-25609 |
Regulation |
denotes |
regulated |
| T17175 |
25739-25747 |
Regulation |
denotes |
involved |
| T17176 |
25755-25764 |
Positive_regulation |
denotes |
induction |
| T17177 |
25768-25773 |
Protein |
denotes |
IL-17 |
| T17074 |
25768-25773 |
Protein |
denotes |
IL-17 |
| T17178 |
25810-25813 |
Protein |
denotes |
CD3 |
| T17075 |
25810-25813 |
Protein |
denotes |
CD3 |
| T17179 |
25814-25821 |
Positive_regulation |
denotes |
induced |
| T17180 |
25822-25827 |
Protein |
denotes |
IL-17 |
| T17076 |
25822-25827 |
Protein |
denotes |
IL-17 |
| T17181 |
25828-25838 |
Gene_expression |
denotes |
production |
| T17182 |
25868-25876 |
Negative_regulation |
denotes |
hampered |
| T17183 |
26027-26034 |
Positive_regulation |
denotes |
induced |
| T17184 |
26035-26040 |
Protein |
denotes |
IL-17 |
| T17077 |
26035-26040 |
Protein |
denotes |
IL-17 |
| T17185 |
26041-26051 |
Gene_expression |
denotes |
production |
| T17186 |
26056-26069 |
Negative_regulation |
denotes |
downregulated |
| T17187 |
26110-26119 |
Negative_regulation |
denotes |
inhibitor |
| T17188 |
26220-26232 |
Protein |
denotes |
IκB kinase-β |
| T17078 |
26220-26232 |
Protein |
denotes |
IκB kinase-β |
| T17189 |
26236-26245 |
Positive_regulation |
denotes |
activated |
| T17190 |
26344-26348 |
Protein |
denotes |
p300 |
| T17079 |
26344-26348 |
Protein |
denotes |
p300 |
| T17191 |
26349-26369 |
Protein |
denotes |
CREB-binding protein |
| T17080 |
26349-26369 |
Protein |
denotes |
CREB-binding protein |
| T17192 |
26466-26473 |
Binding |
denotes |
binding |
| T17193 |
26487-26496 |
Negative_regulation |
denotes |
decreased |
| T17194 |
26643-26648 |
Protein |
denotes |
IL-17 |
| T17081 |
26643-26648 |
Protein |
denotes |
IL-17 |
| T17195 |
26649-26659 |
Gene_expression |
denotes |
production |
| T17196 |
26784-26787 |
Protein |
denotes |
Akt |
| T17082 |
26784-26787 |
Protein |
denotes |
Akt |
| T17197 |
26788-26798 |
Positive_regulation |
denotes |
activation |
| T17198 |
26823-26827 |
Negative_regulation |
denotes |
loss |
| T17199 |
26866-26869 |
Protein |
denotes |
Akt |
| T17083 |
26866-26869 |
Protein |
denotes |
Akt |
| T17200 |
26873-26887 |
Phosphorylation |
denotes |
phosphorylated |
| T17201 |
26963-26972 |
Positive_regulation |
denotes |
induction |
| T17202 |
26976-26981 |
Protein |
denotes |
IL-17 |
| T17084 |
26976-26981 |
Protein |
denotes |
IL-17 |
| T17203 |
27029-27038 |
Positive_regulation |
denotes |
activated |
| T17204 |
27056-27060 |
Protein |
denotes |
CD28 |
| T17085 |
27056-27060 |
Protein |
denotes |
CD28 |
| T17205 |
27062-27067 |
Protein |
denotes |
IL-15 |
| T17086 |
27062-27067 |
Protein |
denotes |
IL-15 |
| T17206 |
27174-27183 |
Positive_regulation |
denotes |
induction |
| T17207 |
27187-27192 |
Protein |
denotes |
IL-17 |
| T17087 |
27187-27192 |
Protein |
denotes |
IL-17 |
| T17208 |
27222-27226 |
Protein |
denotes |
AP-1 |
| T17088 |
27222-27226 |
Protein |
denotes |
AP-1 |
| T17209 |
27413-27416 |
Protein |
denotes |
Akt |
| T17089 |
27413-27416 |
Protein |
denotes |
Akt |
| T17210 |
27420-27431 |
Binding |
denotes |
association |
| T17211 |
27535-27543 |
Positive_regulation |
denotes |
inducing |
| T17212 |
27544-27549 |
Protein |
denotes |
IL-17 |
| T17090 |
27544-27549 |
Protein |
denotes |
IL-17 |
| T17213 |
27554-27561 |
Negative_regulation |
denotes |
lacking |
| T17214 |
27603-27606 |
Protein |
denotes |
Akt |
| T17091 |
27603-27606 |
Protein |
denotes |
Akt |
| T17215 |
27678-27690 |
Positive_regulation |
denotes |
upregulation |
| T17216 |
27694-27699 |
Protein |
denotes |
IL-17 |
| T17092 |
27694-27699 |
Protein |
denotes |
IL-17 |
| T17217 |
27778-27785 |
Binding |
denotes |
binding |
| T17218 |
27802-27807 |
Protein |
denotes |
IL-17 |
| T17093 |
27802-27807 |
Protein |
denotes |
IL-17 |
| T17219 |
27808-27816 |
Entity |
denotes |
promoter |
| T17220 |
27915-27920 |
Protein |
denotes |
IL-17 |
| T17094 |
27915-27920 |
Protein |
denotes |
IL-17 |
| T17221 |
27996-28001 |
Protein |
denotes |
IL-17 |
| T17095 |
27996-28001 |
Protein |
denotes |
IL-17 |
| T22079 |
28136-28146 |
Gene_expression |
denotes |
production |
| T22080 |
28150-28155 |
Protein |
denotes |
IL-17 |
| T22071 |
28150-28155 |
Protein |
denotes |
IL-17 |
| T22081 |
28184-28189 |
Protein |
denotes |
IL-15 |
| T22072 |
28184-28189 |
Protein |
denotes |
IL-15 |
| T22082 |
28194-28199 |
Protein |
denotes |
MCP-1 |
| T22073 |
28194-28199 |
Protein |
denotes |
MCP-1 |
| T22083 |
28240-28244 |
Protein |
denotes |
CD28 |
| T22074 |
28240-28244 |
Protein |
denotes |
CD28 |
| T22084 |
28270-28282 |
Positive_regulation |
denotes |
upregulation |
| T22085 |
28286-28291 |
Protein |
denotes |
IL-17 |
| T22075 |
28286-28291 |
Protein |
denotes |
IL-17 |
| T22086 |
28380-28383 |
Protein |
denotes |
Akt |
| T22076 |
28380-28383 |
Protein |
denotes |
Akt |
| T22087 |
28483-28493 |
Regulation |
denotes |
regulation |
| T22088 |
28497-28502 |
Protein |
denotes |
IL-17 |
| T22077 |
28497-28502 |
Protein |
denotes |
IL-17 |
| T22089 |
28503-28513 |
Gene_expression |
denotes |
production |
| T22090 |
28675-28680 |
Protein |
denotes |
IL-17 |
| T22078 |
28675-28680 |
Protein |
denotes |
IL-17 |
| R1090 |
T2188 |
T2187 |
themeOf |
tumor necrosis factor (TNF)-α,inhibitors |
| R1091 |
T2189 |
T2187 |
themeOf |
interleukin (IL)-1,inhibitors |
| R1092 |
T2197 |
T2198 |
causeOf |
IL-17,induce |
| R1093 |
T2199 |
T2198 |
themeOf |
IL-6,induce |
| R1094 |
T2200 |
T2198 |
themeOf |
IL-8,induce |
| R1095 |
T2201 |
T2204 |
themeOf |
TNF-α,produced |
| R1096 |
T2202 |
T2204 |
themeOf |
IL-1,produced |
| R1097 |
T2203 |
T2204 |
themeOf |
IL-17,produced |
| R1098 |
T2207 |
T2206 |
themeOf |
RANKL,induction |
| R1099 |
T2208 |
T2207 |
equivalentTo |
receptor activator of nuclear factor κB [NF-κB] ligand,RANKL |
| R1100 |
T2210 |
T2209 |
themeOf |
production,stimulates |
| R1101 |
T2211 |
T2210 |
themeOf |
IL-6,production |
| R1102 |
T2213 |
T2214 |
themeOf |
IL-17,produced |
| R1103 |
T2218 |
T2219 |
themeOf |
IL-17,production |
| R1104 |
T2219 |
T2217 |
themeOf |
production,trigger |
| R1105 |
T2220 |
T2221 |
causeOf |
IL-23,trigger |
| R1106 |
T2222 |
T2223 |
themeOf |
IL-17,production |
| R1107 |
T2223 |
T2221 |
themeOf |
production,trigger |
| R1108 |
T2227 |
T2228 |
themeOf |
IL-17,production |
| R1109 |
T2229 |
T2230 |
themeOf |
IL-17,production |
| R12065 |
T22080 |
T22079 |
themeOf |
IL-17,production |
| R12066 |
T22085 |
T22084 |
themeOf |
IL-17,upregulation |
| R12067 |
T22088 |
T22089 |
themeOf |
IL-17,production |
| R12068 |
T22089 |
T22087 |
themeOf |
production,regulation |
| R2808 |
T5258 |
T5257 |
equivalentTo |
MCP-1,monocyte chemoattractant protein-1 |
| R2809 |
T5267 |
T5266 |
equivalentTo |
PHA,Phytohemagglutinin |
| R30 |
T129 |
T130 |
themeOf |
interleukin-17,production |
| R31 |
T130 |
T128 |
themeOf |
production,Increased |
| R3142 |
T5915 |
T5914 |
themeOf |
IL-17,Production |
| R32 |
T131 |
T128 |
causeOf |
Akt,Increased |
| R33 |
T135 |
T136 |
causeOf |
IL-23,regulate |
| R34 |
T137 |
T138 |
themeOf |
IL-17,production |
| R35 |
T138 |
T136 |
themeOf |
production,regulate |
| R36 |
T140 |
T141 |
themeOf |
IL-17,production |
| R37 |
T141 |
T139 |
themeOf |
production,regulate |
| R38 |
T144 |
T145 |
themeOf |
IL-17,production |
| R39 |
T145 |
T143 |
themeOf |
production,regulation |
| R40 |
T148 |
T147 |
equivalentTo |
PHA,phytohemagglutinin |
| R41 |
T150 |
T152 |
themeOf |
production,increased |
| R42 |
T151 |
T150 |
themeOf |
IL-17,production |
| R43 |
T154 |
T152 |
causeOf |
PHA,increased |
| R44 |
T155 |
T158 |
causeOf |
IL-15,upregulated |
| R4473 |
T8210 |
T8209 |
equivalentTo |
GAPDH,glyceraldehyde-3-phosphate dehydrogenase |
| R4474 |
T8217 |
T8216 |
themeOf |
IL-17,mRNA expression |
| R4475 |
T8218 |
T8216 |
themeOf |
GAPDH,mRNA expression |
| R45 |
T156 |
T158 |
causeOf |
monocyte chemoattractant protein-1,upregulated |
| R46 |
T156 |
T160 |
themeOf |
monocyte chemoattractant protein-1,production |
| R47 |
T157 |
T158 |
causeOf |
IL-6,upregulated |
| R48 |
T159 |
T160 |
themeOf |
IL-17,production |
| R4826 |
T9207 |
T9212 |
themeOf |
IκB-α,phosphorylated |
| R4827 |
T9213 |
T9212 |
themeOf |
Akt,phosphorylated |
| R4828 |
T9216 |
T9215 |
themeOf |
Akt,phosphorylated |
| R4829 |
T9217 |
T9215 |
themeOf |
IκB-α,phosphorylated |
| R49 |
T160 |
T158 |
themeOf |
production,upregulated |
| R50 |
T165 |
T166 |
themeOf |
IL-17,expression |
| R51 |
T170 |
T171 |
themeOf |
IL-17,production |
| R52 |
T173 |
T174 |
themeOf |
Akt,inhibitor |
| R53 |
T175 |
T179 |
causeOf |
inhibition,affect |
| R54 |
T176 |
T175 |
themeOf |
activator protein-1,inhibition |
| R55 |
T177 |
T179 |
causeOf |
extracellular signal-regulated kinase 1,affect |
| R56 |
T177 |
T175 |
themeOf |
extracellular signal-regulated kinase 1,inhibition |
| R57 |
T178 |
T175 |
themeOf |
2,inhibition |
| R58 |
T180 |
T181 |
themeOf |
IL-17,production |
| R59 |
T181 |
T179 |
themeOf |
production,affect |
| R5994 |
T11101 |
T11102 |
themeOf |
IL-17,production |
| R5995 |
T11105 |
T11106 |
themeOf |
IL-17,secretion |
| R5996 |
T11107 |
T11108 |
themeOf |
IL-17,production |
| R5997 |
T11108 |
T11109 |
themeOf |
production,stimulated |
| R5998 |
T11108 |
T11111 |
themeOf |
production,higher |
| R5999 |
T11109 |
T11111 |
themeOf |
stimulated,higher |
| R6000 |
T11110 |
T11109 |
causeOf |
PHA,stimulated |
| R6317 |
T11658 |
T11659 |
themeOf |
IL-17,production |
| R6318 |
T11659 |
T11657 |
themeOf |
production,Increased |
| R6319 |
T11661 |
T11657 |
causeOf |
PHA,Increased |
| R6320 |
T11662 |
T11663 |
themeOf |
IL-17,produced |
| R6321 |
T11666 |
T11665 |
themeOf |
IL-17,increase |
| R6322 |
T11668 |
T11669 |
themeOf |
IL-17,production |
| R6323 |
T11669 |
T11667 |
themeOf |
production,upregulated |
| R6324 |
T11672 |
T11671 |
themeOf |
IL-17,produced |
| R6325 |
T11675 |
T11676 |
themeOf |
IL-17,production |
| R6326 |
T11676 |
T11674 |
themeOf |
production,increased |
| R6750 |
T12425 |
T12426 |
themeOf |
IL-17,production |
| R6751 |
T12426 |
T12424 |
themeOf |
production,Regulation |
| R6752 |
T12428 |
T12427 |
themeOf |
production,affected |
| R6753 |
T12429 |
T12428 |
themeOf |
IL-17,production |
| R6754 |
T12430 |
T12431 |
themeOf |
IL-17,production |
| R6755 |
T12433 |
T12432 |
themeOf |
IL-17,increase |
| R6756 |
T12434 |
T12432 |
causeOf |
IL-15,increase |
| R6757 |
T12435 |
T12432 |
causeOf |
IL-1β,increase |
| R6758 |
T12436 |
T12432 |
causeOf |
TNF-α,increase |
| R6759 |
T12438 |
T12432 |
causeOf |
TGF-β,increase |
| R6760 |
T12439 |
T12432 |
causeOf |
IL-17,increase |
| R7271 |
T13340 |
T13341 |
themeOf |
IL-17,production |
| R7272 |
T13341 |
T13339 |
themeOf |
production,Inhibition |
| R7273 |
T13343 |
T13344 |
themeOf |
IL-17,production |
| R7274 |
T13344 |
T13342 |
themeOf |
production,increased |
| R7275 |
T13346 |
T13345 |
themeOf |
induced,decrease |
| R7276 |
T13347 |
T13348 |
themeOf |
IL-17,production |
| R7277 |
T13348 |
T13346 |
themeOf |
production,induced |
| R7278 |
T13350 |
T13349 |
themeOf |
induced,inhibited |
| R7279 |
T13351 |
T13352 |
themeOf |
IL-17,production |
| R7280 |
T13352 |
T13350 |
themeOf |
production,induced |
| R7281 |
T13353 |
T13354 |
causeOf |
calcineurin,downregulated |
| R7282 |
T13355 |
T13356 |
themeOf |
IL-17,secretion |
| R7283 |
T13356 |
T13354 |
themeOf |
secretion,downregulated |
| R7284 |
T13360 |
T13361 |
themeOf |
IL-17,production |
| R7285 |
T13361 |
T13359 |
themeOf |
production,inhibition |
| R7286 |
T13364 |
T13365 |
themeOf |
IL-17,production |
| R7287 |
T13365 |
T13363 |
themeOf |
production,inhibitions |
| R7965 |
T14424 |
T14425 |
themeOf |
IL-17,mRNA expression |
| R7966 |
T14426 |
T14429 |
themeOf |
enhanced,regulated |
| R7967 |
T14427 |
T14428 |
themeOf |
IL-17,production |
| R7968 |
T14428 |
T14429 |
themeOf |
production,regulated |
| R7969 |
T14428 |
T14426 |
themeOf |
production,enhanced |
| R7970 |
T14433 |
T14431 |
themeOf |
mRNA,increase |
| R7971 |
T14434 |
T14431 |
themeOf |
transcripts,increase |
| R7972 |
T14436 |
T14435 |
causeOf |
inhibitor,inhibited |
| R8142 |
T14749 |
T14750 |
themeOf |
IL-17,production |
| R8143 |
T14752 |
T14751 |
themeOf |
Akt,activation |
| R8144 |
T14754 |
T14753 |
themeOf |
Akt,phosphorylated |
| R8145 |
T14756 |
T14755 |
themeOf |
Akt,phosphorylated |
| R8146 |
T14759 |
T14758 |
themeOf |
Akt,phosphorylated |
| R8147 |
T14761 |
T14763 |
causeOf |
PHA,effect |
| R8148 |
T14762 |
T14763 |
causeOf |
IL-15,effect |
| R8149 |
T14764 |
T14763 |
themeOf |
phosphorylated,effect |
| R8150 |
T14765 |
T14764 |
themeOf |
Akt,phosphorylated |
| R8554 |
T15553 |
T15552 |
equivalentTo |
AP-1,activator protein-1 |
| R8555 |
T15556 |
T15558 |
causeOf |
PHA,inducing |
| R8556 |
T15559 |
T15560 |
themeOf |
IL-17,expression |
| R8557 |
T15560 |
T15558 |
themeOf |
expression,inducing |
| R8558 |
T15564 |
T15563 |
themeOf |
binding,increased |
| R8559 |
T15571 |
T15570 |
themeOf |
binding,block |
| R8560 |
T15575 |
T15574 |
themeOf |
degradation,inhibition |
| R8561 |
T15576 |
T15574 |
themeOf |
IκB-α,inhibition |
| R8562 |
T15576 |
T15575 |
themeOf |
IκB-α,degradation |
| R8563 |
T15579 |
T15580 |
themeOf |
IL-17,production |
| R9267 |
T17102 |
T17103 |
themeOf |
IL-17,production |
| R9268 |
T17103 |
T17104 |
themeOf |
production,regulated |
| R9269 |
T17107 |
T17108 |
themeOf |
IL-17,production |
| R9270 |
T17108 |
T17106 |
themeOf |
production,stimulate |
| R9271 |
T17109 |
T17110 |
themeOf |
IL-17,production |
| R9272 |
T17110 |
T17106 |
themeOf |
production,stimulate |
| R9273 |
T17112 |
T17114 |
causeOf |
PHA,increased |
| R9274 |
T17114 |
T17117 |
themeOf |
increased,dependent |
| R9275 |
T17115 |
T17116 |
themeOf |
IL-17,production |
| R9276 |
T17116 |
T17114 |
themeOf |
production,increased |
| R9277 |
T17116 |
T17117 |
themeOf |
production,dependent |
| R9278 |
T17118 |
T17120 |
themeOf |
upregulation,due |
| R9279 |
T17119 |
T17118 |
themeOf |
IL-17,upregulation |
| R9280 |
T17121 |
T17122 |
themeOf |
IL-17,produced |
| R9281 |
T17127 |
T17128 |
themeOf |
IL-17,production |
| R9282 |
T17128 |
T17129 |
themeOf |
production,augmented |
| R9283 |
T17135 |
T17136 |
themeOf |
IL-17,production |
| R9284 |
T17136 |
T17134 |
themeOf |
production,stimulate |
| R9285 |
T17138 |
T17134 |
causeOf |
IL-23,stimulate |
| R9286 |
T17140 |
T17141 |
themeOf |
IL-17,production |
| R9287 |
T17141 |
T17139 |
themeOf |
production,regulate |
| R9288 |
T17143 |
T17142 |
themeOf |
IL-17,production |
| R9289 |
T17148 |
T17147 |
themeOf |
production,increased |
| R9290 |
T17149 |
T17148 |
themeOf |
IL-17,production |
| R9291 |
T17153 |
T17154 |
themeOf |
IL-17,production |
| R9292 |
T17154 |
T17152 |
themeOf |
production,augmented |
| R9293 |
T17155 |
T17158 |
causeOf |
IL-1,affect |
| R9294 |
T17159 |
T17160 |
themeOf |
IL-17,production |
| R9295 |
T17160 |
T17158 |
themeOf |
production,affect |
| R9296 |
T17161 |
T17162 |
causeOf |
IL-15,triggered |
| R9297 |
T17163 |
T17164 |
themeOf |
IL-17,production |
| R9298 |
T17164 |
T17162 |
themeOf |
production,triggered |
| R9299 |
T17169 |
T17170 |
themeOf |
IL-17,induction |
| R9300 |
T17170 |
T17168 |
themeOf |
induction,increases |
| R9301 |
T17172 |
T17173 |
themeOf |
IL-17,production |
| R9302 |
T17173 |
T17174 |
themeOf |
production,regulated |
| R9303 |
T17176 |
T17175 |
themeOf |
induction,involved |
| R9304 |
T17177 |
T17176 |
themeOf |
IL-17,induction |
| R9305 |
T17178 |
T17179 |
causeOf |
CD3,induced |
| R9306 |
T17179 |
T17182 |
themeOf |
induced,hampered |
| R9307 |
T17180 |
T17181 |
themeOf |
IL-17,production |
| R9308 |
T17181 |
T17182 |
themeOf |
production,hampered |
| R9309 |
T17181 |
T17179 |
themeOf |
production,induced |
| R9310 |
T17183 |
T17186 |
themeOf |
induced,downregulated |
| R9311 |
T17184 |
T17185 |
themeOf |
IL-17,production |
| R9312 |
T17185 |
T17186 |
themeOf |
production,downregulated |
| R9313 |
T17185 |
T17183 |
themeOf |
production,induced |
| R9314 |
T17187 |
T17186 |
causeOf |
inhibitor,downregulated |
| R9315 |
T17188 |
T17189 |
themeOf |
IκB kinase-β,activated |
| R9316 |
T17192 |
T17193 |
themeOf |
binding,decreased |
| R9317 |
T17194 |
T17195 |
themeOf |
IL-17,production |
| R9318 |
T17196 |
T17197 |
themeOf |
Akt,activation |
| R9319 |
T17199 |
T17200 |
themeOf |
Akt,phosphorylated |
| R9320 |
T17202 |
T17201 |
themeOf |
IL-17,induction |
| R9321 |
T17207 |
T17206 |
themeOf |
IL-17,induction |
| R9322 |
T17209 |
T17210 |
themeOf |
Akt,association |
| R9323 |
T17212 |
T17213 |
themeOf |
IL-17,lacking |
| R9324 |
T17216 |
T17215 |
themeOf |
IL-17,upregulation |
| R9325 |
T17219 |
T17218 |
partOf |
promoter,IL-17 |
| R9326 |
T17219 |
T17217 |
themeOf |
promoter,binding |
