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PubMed:32363391 JSONTXT 22 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 0-98 Sentence denotes Deducing the N- and O- glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2.
T1 0-98 Sentence denotes Deducing the N- and O- glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2.
T2 99-271 Sentence denotes The current emergence of the novel coronavirus pandemic caused by SARS-CoV-2 demands the development of new therapeutic strategies to prevent rapid progress of mortalities.
T2 99-271 Sentence denotes The current emergence of the novel coronavirus pandemic caused by SARS-CoV-2 demands the development of new therapeutic strategies to prevent rapid progress of mortalities.
T3 272-466 Sentence denotes The coronavirus spike (S) protein, which facilitates viral attachment, entry and membrane fusion is heavily glycosylated and plays a critical role in the elicitation of the host immune response.
T3 272-466 Sentence denotes The coronavirus spike (S) protein, which facilitates viral attachment, entry and membrane fusion is heavily glycosylated and plays a critical role in the elicitation of the host immune response.
T4 467-593 Sentence denotes The spike protein is comprised of two protein subunits (S1 and S2), which together possess 22 potential N-glycosylation sites.
T4 467-593 Sentence denotes The spike protein is comprised of two protein subunits (S1 and S2), which together possess 22 potential N-glycosylation sites.
T5 594-741 Sentence denotes Herein, we report the glycosylation mapping on spike protein subunits S1 and S2 expressed on human cells through high resolution mass spectrometry.
T5 594-741 Sentence denotes Herein, we report the glycosylation mapping on spike protein subunits S1 and S2 expressed on human cells through high resolution mass spectrometry.
T6 742-956 Sentence denotes We have characterized the quantitative N-glycosylation profile on spike protein and interestingly, observed unexpected O-glycosylation modifications on the receptor binding domain (RBD) of spike protein subunit S1.
T6 742-956 Sentence denotes We have characterized the quantitative N-glycosylation profile on spike protein and interestingly, observed unexpected O-glycosylation modifications on the receptor binding domain (RBD) of spike protein subunit S1.
T7 957-1180 Sentence denotes Even though O-glycosylation has been predicted on the spike protein of SARS-CoV-2, this is the first report of experimental data for both the site of O-glycosylation and identity of the O-glycans attached on the subunit S1.
T7 957-1180 Sentence denotes Even though O-glycosylation has been predicted on the spike protein of SARS-CoV-2, this is the first report of experimental data for both the site of O-glycosylation and identity of the O-glycans attached on the subunit S1.
T8 1181-1407 Sentence denotes Our data on the N- and O- glycosylation is strengthened by extensive manual interpretation of each glycopeptide spectra in addition to using bioinformatics tools to confirm the complexity of glycosylation in the spike protein.
T8 1181-1407 Sentence denotes Our data on the N- and O- glycosylation is strengthened by extensive manual interpretation of each glycopeptide spectra in addition to using bioinformatics tools to confirm the complexity of glycosylation in the spike protein.
T9 1408-1614 Sentence denotes The elucidation of the glycan repertoire on the spike protein provides insights into the viral binding studies and more importantly, propels research towards the development of a suitable vaccine candidate.
T9 1408-1614 Sentence denotes The elucidation of the glycan repertoire on the spike protein provides insights into the viral binding studies and more importantly, propels research towards the development of a suitable vaccine candidate.