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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-100 Sentence denotes Relationship between phosphorylation of sperm-specific antigen and prognosis of lung adenocarcinoma.
T1 0-100 Sentence denotes Relationship between phosphorylation of sperm-specific antigen and prognosis of lung adenocarcinoma.
TextSentencer_T2 101-112 Sentence denotes UNLABELLED:
T2 101-112 Sentence denotes UNLABELLED:
TextSentencer_T3 113-178 Sentence denotes Lung cancer is generally considered as a highly malignant cancer.
T3 113-178 Sentence denotes Lung cancer is generally considered as a highly malignant cancer.
TextSentencer_T4 179-313 Sentence denotes A major challenge for the management of lung adenocarcinoma patients is to predict the clinical course of the disease after resection.
T4 179-313 Sentence denotes A major challenge for the management of lung adenocarcinoma patients is to predict the clinical course of the disease after resection.
TextSentencer_T5 314-638 Sentence denotes We analyzed the different levels of phosphorylation of proteins in lung adenocarcinoma tissues between a poor prognosis (PP) group, in which six patients exhibited recurrence within five years after surgery, and a good prognosis (GP) group, in which seven patients did not exhibit recurrence within five years after surgery.
T5 314-638 Sentence denotes We analyzed the different levels of phosphorylation of proteins in lung adenocarcinoma tissues between a poor prognosis (PP) group, in which six patients exhibited recurrence within five years after surgery, and a good prognosis (GP) group, in which seven patients did not exhibit recurrence within five years after surgery.
TextSentencer_T6 639-771 Sentence denotes We found that phosphorylation at Ser92 of the sperm-specific antigen 2 (SSFA2) [phospho-SSFA2(pS92)] was stimulated in the PP group.
T6 639-771 Sentence denotes We found that phosphorylation at Ser92 of the sperm-specific antigen 2 (SSFA2) [phospho-SSFA2(pS92)] was stimulated in the PP group.
TextSentencer_T7 772-970 Sentence denotes Using samples from a total of 46 patients, we investigated the utility of phospho-SSFA2(pS92) to discriminate patients of GP and PP groups, with multiple reaction monitoring (MRM) mass spectrometry.
T7 772-970 Sentence denotes Using samples from a total of 46 patients, we investigated the utility of phospho-SSFA2(pS92) to discriminate patients of GP and PP groups, with multiple reaction monitoring (MRM) mass spectrometry.
TextSentencer_T8 971-1070 Sentence denotes Consequently, we confirmed that the PP group had significantly elevated phospho-SSFA2(pS92) levels.
T8 971-1070 Sentence denotes Consequently, we confirmed that the PP group had significantly elevated phospho-SSFA2(pS92) levels.
TextSentencer_T9 1071-1146 Sentence denotes Additionally, no expression of SSFA2 recognized in the normal lung tissues.
T9 1071-1146 Sentence denotes Additionally, no expression of SSFA2 recognized in the normal lung tissues.
TextSentencer_T10 1147-1275 Sentence denotes From these results, we demonstrate that phospho-SSFA2 (pS92) is related to the prognosis of early resected lung adenocarcinomas.
T10 1147-1275 Sentence denotes From these results, we demonstrate that phospho-SSFA2 (pS92) is related to the prognosis of early resected lung adenocarcinomas.
TextSentencer_T11 1276-1406 Sentence denotes Therefore, we suggest that phosphorylation of this protein indicates its role as a potential biomarker and new therapeutic target.
T11 1276-1406 Sentence denotes Therefore, we suggest that phosphorylation of this protein indicates its role as a potential biomarker and new therapeutic target.
TextSentencer_T12 1407-1431 Sentence denotes BIOLOGICAL SIGNIFICANCE:
T12 1407-1431 Sentence denotes BIOLOGICAL SIGNIFICANCE:
TextSentencer_T13 1432-1518 Sentence denotes Lung adenocarcinoma patients often experience a high rate of recurrence after surgery.
T13 1432-1518 Sentence denotes Lung adenocarcinoma patients often experience a high rate of recurrence after surgery.
TextSentencer_T14 1519-1657 Sentence denotes It is important to discover biomarkers for prognostic prediction and therapeutic targets for treatment of early-stage lung adenocarcinoma.
T14 1519-1657 Sentence denotes It is important to discover biomarkers for prognostic prediction and therapeutic targets for treatment of early-stage lung adenocarcinoma.
TextSentencer_T15 1658-1912 Sentence denotes In this study, using tissue samples obtained from patients with lung adenocarcinoma that had been stored for five years at -80°C, we identified 13 unique phosphorylated peptides, which were differentially expressed between poor and good prognosis groups.
T15 1658-1912 Sentence denotes In this study, using tissue samples obtained from patients with lung adenocarcinoma that had been stored for five years at -80°C, we identified 13 unique phosphorylated peptides, which were differentially expressed between poor and good prognosis groups.
TextSentencer_T16 1913-2049 Sentence denotes We confirmed that phosphorylation at Ser92 of the sperm-specific antigen 2 (SSFA2)[phospho-SSFA2 (pS92)], was related to poor prognosis.
T16 1913-2049 Sentence denotes We confirmed that phosphorylation at Ser92 of the sperm-specific antigen 2 (SSFA2)[phospho-SSFA2 (pS92)], was related to poor prognosis.
TextSentencer_T17 2050-2203 Sentence denotes Our study demonstrates that prognostic prediction of early-stage lung adenocarcinoma is possible, and suggests new therapeutic targets for its treatment.
T17 2050-2203 Sentence denotes Our study demonstrates that prognostic prediction of early-stage lung adenocarcinoma is possible, and suggests new therapeutic targets for its treatment.