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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-82 Sentence denotes MT1-MMP protects breast carcinoma cells against type I collagen-induced apoptosis.
T1 0-82 Sentence denotes MT1-MMP protects breast carcinoma cells against type I collagen-induced apoptosis.
TextSentencer_T2 83-260 Sentence denotes As invading breast carcinoma cells breach their underlying basement membrane, they become confronted with a dense three-dimensional reactive stroma dominated by type I collagen.
T2 83-260 Sentence denotes As invading breast carcinoma cells breach their underlying basement membrane, they become confronted with a dense three-dimensional reactive stroma dominated by type I collagen.
TextSentencer_T3 261-385 Sentence denotes To develop metastatic capabilities, invading tumor cells must acquire the capacity to negotiate this novel microenvironment.
T3 261-385 Sentence denotes To develop metastatic capabilities, invading tumor cells must acquire the capacity to negotiate this novel microenvironment.
TextSentencer_T4 386-457 Sentence denotes Collagen influences the fate of epithelial cells by inducing apoptosis.
T4 386-457 Sentence denotes Collagen influences the fate of epithelial cells by inducing apoptosis.
TextSentencer_T5 458-568 Sentence denotes However, the mechanisms used by invading tumor cells to evade collagen-induced apoptosis remain to be defined.
T5 458-568 Sentence denotes However, the mechanisms used by invading tumor cells to evade collagen-induced apoptosis remain to be defined.
TextSentencer_T6 569-786 Sentence denotes We demonstrate that membrane type-1 matrix metalloproteinase (MT1-MMP/MMP-14) confers breast cancer cells with the ability to escape apoptosis when embedded in a collagen gel and after orthotopic implantation in vivo.
T6 569-786 Sentence denotes We demonstrate that membrane type-1 matrix metalloproteinase (MT1-MMP/MMP-14) confers breast cancer cells with the ability to escape apoptosis when embedded in a collagen gel and after orthotopic implantation in vivo.
TextSentencer_T7 787-979 Sentence denotes In the absence of MMP-14-dependent proteolysis, type I collagen triggers apoptosis by inducing the expression of the pro-apoptotic Bcl-2-interacting killer in luminal-like breast cancer cells.
T7 787-979 Sentence denotes In the absence of MMP-14-dependent proteolysis, type I collagen triggers apoptosis by inducing the expression of the pro-apoptotic Bcl-2-interacting killer in luminal-like breast cancer cells.
TextSentencer_T8 980-1096 Sentence denotes These findings reveal a new mechanism whereby MMP-14 activity promotes tumor progression by circumventing apoptosis.
T8 980-1096 Sentence denotes These findings reveal a new mechanism whereby MMP-14 activity promotes tumor progression by circumventing apoptosis.