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PubMed:19451548 JSONTXT 55 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-97 Sentence denotes Quality control of glycoproteins bearing truncated glycans in an ALG9-defective (CDG-IL) patient.
T1 0-97 Sentence denotes Quality control of glycoproteins bearing truncated glycans in an ALG9-defective (CDG-IL) patient.
T1 0-97 Sentence denotes Quality control of glycoproteins bearing truncated glycans in an ALG9-defective (CDG-IL) patient.
TextSentencer_T2 98-238 Sentence denotes We describe an ALG9-defective (congenital disorders of glycosylation type IL) patient who is homozygous for the p.Y286C (c.860A>G) mutation.
T2 98-238 Sentence denotes We describe an ALG9-defective (congenital disorders of glycosylation type IL) patient who is homozygous for the p.Y286C (c.860A>G) mutation.
T2 98-238 Sentence denotes We describe an ALG9-defective (congenital disorders of glycosylation type IL) patient who is homozygous for the p.Y286C (c.860A>G) mutation.
TextSentencer_T3 239-395 Sentence denotes This patient presented with psychomotor retardation, axial hypotonia, epilepsy, failure to thrive, inverted nipples, hepatomegaly, and pericardial effusion.
T3 239-395 Sentence denotes This patient presented with psychomotor retardation, axial hypotonia, epilepsy, failure to thrive, inverted nipples, hepatomegaly, and pericardial effusion.
T3 239-395 Sentence denotes This patient presented with psychomotor retardation, axial hypotonia, epilepsy, failure to thrive, inverted nipples, hepatomegaly, and pericardial effusion.
TextSentencer_T4 396-556 Sentence denotes Due to the ALG9 deficiency, the cells of this patient accumulated the lipid-linked oligosaccharides Man(6)GlcNAc(2)-PP-dolichol and Man(8)GlcNAc(2)-PP-dolichol.
T4 396-556 Sentence denotes Due to the ALG9 deficiency, the cells of this patient accumulated the lipid-linked oligosaccharides Man(6)GlcNAc(2)-PP-dolichol and Man(8)GlcNAc(2)-PP-dolichol.
T4 396-556 Sentence denotes Due to the ALG9 deficiency, the cells of this patient accumulated the lipid-linked oligosaccharides Man(6)GlcNAc(2)-PP-dolichol and Man(8)GlcNAc(2)-PP-dolichol.
TextSentencer_T5 557-651 Sentence denotes It is known that the oligosaccharide structure has a profound effect on protein glycosylation.
T5 557-651 Sentence denotes It is known that the oligosaccharide structure has a profound effect on protein glycosylation.
T5 557-651 Sentence denotes It is known that the oligosaccharide structure has a profound effect on protein glycosylation.
TextSentencer_T6 652-914 Sentence denotes Therefore, we investigated the influence of these truncated oligosaccharide structures on the protein transfer efficiency, the quality control of newly synthesized glycoproteins, and the eventual degradation of the truncated glycoproteins formed in this patient.
T6 652-914 Sentence denotes Therefore, we investigated the influence of these truncated oligosaccharide structures on the protein transfer efficiency, the quality control of newly synthesized glycoproteins, and the eventual degradation of the truncated glycoproteins formed in this patient.
T6 652-914 Sentence denotes Therefore, we investigated the influence of these truncated oligosaccharide structures on the protein transfer efficiency, the quality control of newly synthesized glycoproteins, and the eventual degradation of the truncated glycoproteins formed in this patient.
TextSentencer_T7 915-1040 Sentence denotes We demonstrated that lipid-linked Man(6)GlcNAc(2) and Man(8)GlcNAc(2) are transferred onto proteins with the same efficiency.
T7 915-1040 Sentence denotes We demonstrated that lipid-linked Man(6)GlcNAc(2) and Man(8)GlcNAc(2) are transferred onto proteins with the same efficiency.
T7 915-1040 Sentence denotes We demonstrated that lipid-linked Man(6)GlcNAc(2) and Man(8)GlcNAc(2) are transferred onto proteins with the same efficiency.
TextSentencer_T8 1041-1251 Sentence denotes In addition, glycoproteins bearing these Man(6)GlcNAc(2) and Man(8)GlcNAc(2) structures efficiently entered in the glucosylation/deglucosylation cycle of the quality control system to assist in protein folding.
T8 1041-1251 Sentence denotes In addition, glycoproteins bearing these Man(6)GlcNAc(2) and Man(8)GlcNAc(2) structures efficiently entered in the glucosylation/deglucosylation cycle of the quality control system to assist in protein folding.
T8 1041-1251 Sentence denotes In addition, glycoproteins bearing these Man(6)GlcNAc(2) and Man(8)GlcNAc(2) structures efficiently entered in the glucosylation/deglucosylation cycle of the quality control system to assist in protein folding.
TextSentencer_T9 1252-1377 Sentence denotes We also showed that in comparison with control cells, patient's cells degraded misfolded glycoproteins at an increasing rate.
T9 1252-1377 Sentence denotes We also showed that in comparison with control cells, patient's cells degraded misfolded glycoproteins at an increasing rate.
T9 1252-1377 Sentence denotes We also showed that in comparison with control cells, patient's cells degraded misfolded glycoproteins at an increasing rate.
TextSentencer_T10 1378-1502 Sentence denotes The Man(8)GlcNAc(2) isomer C on the patient's glycoproteins was found to promote the degradation of misfolded glycoproteins.
T10 1378-1502 Sentence denotes The Man(8)GlcNAc(2) isomer C on the patient's glycoproteins was found to promote the degradation of misfolded glycoproteins.
T10 1378-1502 Sentence denotes The Man(8)GlcNAc(2) isomer C on the patient's glycoproteins was found to promote the degradation of misfolded glycoproteins.