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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-136 Sentence denotes Sequential erythema nodosum leprosum and reversal reaction with similar lesional cytokine mRNA patterns in a borderline leprosy patient.
T1 0-136 Sentence denotes Sequential erythema nodosum leprosum and reversal reaction with similar lesional cytokine mRNA patterns in a borderline leprosy patient.
TextSentencer_T2 137-425 Sentence denotes We compare the clinical and histological data with the immunological status of a borderline leprosy patient who experienced an erythema nodosum leprosum (ENL) reaction followed by a reversal reaction (RR) after 12 weeks of anti-inflammatory treatment (pentoxifylline, PTX, 1200 mg daily).
T2 137-425 Sentence denotes We compare the clinical and histological data with the immunological status of a borderline leprosy patient who experienced an erythema nodosum leprosum (ENL) reaction followed by a reversal reaction (RR) after 12 weeks of anti-inflammatory treatment (pentoxifylline, PTX, 1200 mg daily).
TextSentencer_T3 426-524 Sentence denotes Skin biopsies, serum and blood samples were collected sequentially during the reactional episodes.
T3 426-524 Sentence denotes Skin biopsies, serum and blood samples were collected sequentially during the reactional episodes.
TextSentencer_T4 525-725 Sentence denotes At the outset of RR, the patient's lymphocytes secreted interferon (IFN) -gamma and there was a positive lymphoproliferative test in response to Mycobacterium leprae, which had been absent during ENL.
T4 525-725 Sentence denotes At the outset of RR, the patient's lymphocytes secreted interferon (IFN) -gamma and there was a positive lymphoproliferative test in response to Mycobacterium leprae, which had been absent during ENL.
TextSentencer_T5 726-848 Sentence denotes The lepromin reaction reversed from negative (0 mm) at diagnosis, to positive (3 mm) 3 months after the development of RR.
T5 726-848 Sentence denotes The lepromin reaction reversed from negative (0 mm) at diagnosis, to positive (3 mm) 3 months after the development of RR.
TextSentencer_T6 849-975 Sentence denotes Tumour necrosis factor (TNF) -alpha levels in the serum decreased after 1 week of treatment and increased slightly thereafter.
T6 849-975 Sentence denotes Tumour necrosis factor (TNF) -alpha levels in the serum decreased after 1 week of treatment and increased slightly thereafter.
TextSentencer_T7 976-1225 Sentence denotes The immunohistochemical data for ENL showed a diffuse dermal and hypodermal infiltrate composed of mononuclear cells and neutrophils, while RR was characterized by an epithelioid granulomatous infiltrate with a marked presence of gammadelta T cells.
T7 976-1225 Sentence denotes The immunohistochemical data for ENL showed a diffuse dermal and hypodermal infiltrate composed of mononuclear cells and neutrophils, while RR was characterized by an epithelioid granulomatous infiltrate with a marked presence of gammadelta T cells.
TextSentencer_T8 1226-1483 Sentence denotes Reverse transcription-polymerase chain reaction showed a mixed cytokine profile characterized by the expression of TNF-alpha, IFN-gamma, interleukin (IL) -6, IL-10 and IL-12 mRNA in the skin, which persisted throughout the development of ENL and RR lesions.
T8 1226-1483 Sentence denotes Reverse transcription-polymerase chain reaction showed a mixed cytokine profile characterized by the expression of TNF-alpha, IFN-gamma, interleukin (IL) -6, IL-10 and IL-12 mRNA in the skin, which persisted throughout the development of ENL and RR lesions.
TextSentencer_T9 1484-1569 Sentence denotes IL-4 mRNA, first detected after 7 days of PTX treatment, was still present during RR.
T9 1484-1569 Sentence denotes IL-4 mRNA, first detected after 7 days of PTX treatment, was still present during RR.
TextSentencer_T10 1570-1834 Sentence denotes The results suggest the emergence of an initial Th0-like cytokine profile in ENL, typical of a state of immunoactivation, before conditions optimal for the appearance of an antigen-specific cell-mediated immune response and gammadelta T-cell migration are created.
T10 1570-1834 Sentence denotes The results suggest the emergence of an initial Th0-like cytokine profile in ENL, typical of a state of immunoactivation, before conditions optimal for the appearance of an antigen-specific cell-mediated immune response and gammadelta T-cell migration are created.