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PubMed:10389937 JSONTXT 8 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-133 Sentence denotes High-level expression of EPHB6, EFNB2, and EFNB3 is associated with low tumor stage and high TrkA expression in human neuroblastomas.
T1 0-133 Sentence denotes High-level expression of EPHB6, EFNB2, and EFNB3 is associated with low tumor stage and high TrkA expression in human neuroblastomas.
TextSentencer_T2 134-254 Sentence denotes Neuroblastoma (NB) is a common pediatric tumor of neural crest origin that is biologically and clinically heterogeneous.
T2 134-254 Sentence denotes Neuroblastoma (NB) is a common pediatric tumor of neural crest origin that is biologically and clinically heterogeneous.
TextSentencer_T3 255-366 Sentence denotes EPH family receptor tyrosine kinases and ephrin ligands play fundamental roles in neurodevelopmental processes.
T3 255-366 Sentence denotes EPH family receptor tyrosine kinases and ephrin ligands play fundamental roles in neurodevelopmental processes.
TextSentencer_T4 367-531 Sentence denotes Recently, we found that NB cell lines expressed several EPHB and EFNB transcripts, which encode EPHB subgroup receptors and ephrin-B subgroup ligands, respectively.
T4 367-531 Sentence denotes Recently, we found that NB cell lines expressed several EPHB and EFNB transcripts, which encode EPHB subgroup receptors and ephrin-B subgroup ligands, respectively.
TextSentencer_T5 532-696 Sentence denotes To explore the role of EPHB receptors and ephrin-B ligands in the biology of NB, we examined the expression of EPHB and EFNB transcripts in 47 primary NB specimens.
T5 532-696 Sentence denotes To explore the role of EPHB receptors and ephrin-B ligands in the biology of NB, we examined the expression of EPHB and EFNB transcripts in 47 primary NB specimens.
TextSentencer_T6 697-873 Sentence denotes Multiple EPHB and EFNB transcripts were expressed in all of the NB tumors examined, suggesting the involvement of these transcripts in modulating the biological behavior of NB.
T6 697-873 Sentence denotes Multiple EPHB and EFNB transcripts were expressed in all of the NB tumors examined, suggesting the involvement of these transcripts in modulating the biological behavior of NB.
TextSentencer_T7 874-1077 Sentence denotes Higher levels of EPHB6, EFNB2, and EFNB3 expression were found in low-stage tumors (stage 1, 2, and 4S) than in advanced-stage tumors (stage 3 and 4; P = 0.0013, P = 0.0048, and P = 0.027, respectively).
T7 874-1077 Sentence denotes Higher levels of EPHB6, EFNB2, and EFNB3 expression were found in low-stage tumors (stage 1, 2, and 4S) than in advanced-stage tumors (stage 3 and 4; P = 0.0013, P = 0.0048, and P = 0.027, respectively).
TextSentencer_T8 1078-1273 Sentence denotes Expression of TrkA, a well-established prognostic marker of favorable NB, was positively correlated with EPHB6, EFNB2, and EFNB3 expression (P < 0.0001, P = 0.0019, and P = 0.0001, respectively).
T8 1078-1273 Sentence denotes Expression of TrkA, a well-established prognostic marker of favorable NB, was positively correlated with EPHB6, EFNB2, and EFNB3 expression (P < 0.0001, P = 0.0019, and P = 0.0001, respectively).
TextSentencer_T9 1274-1463 Sentence denotes MYCN-amplified tumors expressed lower levels of EPHB6, EFNB2, EFNB3, and TrkA transcripts compared to nonamplified tumors (P = 0.0006, P = 0.0023, P = 0.0048, and P = 0.0001, respectively).
T9 1274-1463 Sentence denotes MYCN-amplified tumors expressed lower levels of EPHB6, EFNB2, EFNB3, and TrkA transcripts compared to nonamplified tumors (P = 0.0006, P = 0.0023, P = 0.0048, and P = 0.0001, respectively).
TextSentencer_T10 1464-1671 Sentence denotes These data suggest that high-level expression of EPHB6, EFNB2, and EFNB3 is associated with favorable NB and that low-level expression of EPHB6, EFNB2, and EFNB3 correlates with aggressive MYCN-amplified NB.
T10 1464-1671 Sentence denotes These data suggest that high-level expression of EPHB6, EFNB2, and EFNB3 is associated with favorable NB and that low-level expression of EPHB6, EFNB2, and EFNB3 correlates with aggressive MYCN-amplified NB.
TextSentencer_T11 1672-1738 Sentence denotes Thus, EPHB6, EFNB2, and EFNB3 may have biological relevance in NB.
T11 1672-1738 Sentence denotes Thus, EPHB6, EFNB2, and EFNB3 may have biological relevance in NB.
TextSentencer_T12 1739-1841 Sentence denotes Further investigation on the biology of these genes may help provide insight into the treatment of NB.
T12 1739-1841 Sentence denotes Further investigation on the biology of these genes may help provide insight into the treatment of NB.