PMC:3586680 / 2221-3053 JSONTXT 21 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T880 0-160 Sentence denotes Temozolomide induces generation of DNA lesions, including O6-methylguanine, N3-methyladenine, and N7-methylguanine (Goellner et al., 2011; Zhang et al., 2012b).
T16 0-160 Sentence denotes Temozolomide induces generation of DNA lesions, including O6-methylguanine, N3-methyladenine, and N7-methylguanine (Goellner et al., 2011; Zhang et al., 2012b).
T881 161-286 Sentence denotes The O6-methylguanine lesion is known to trigger autophagy, rather than apoptosis, to cause cell death (Kanzawa et al., 2003).
T17 161-286 Sentence denotes The O6-methylguanine lesion is known to trigger autophagy, rather than apoptosis, to cause cell death (Kanzawa et al., 2003).
T882 287-453 Sentence denotes Also, inhibition of antiapoptotic Bcl-2 by a pan-Bcl-2 inhibitor (−)-gossypol leads to autophagic death in gliomas and enhances the action of TMZ (Voss et al., 2010).
T18 287-453 Sentence denotes Also, inhibition of antiapoptotic Bcl-2 by a pan-Bcl-2 inhibitor (−)-gossypol leads to autophagic death in gliomas and enhances the action of TMZ (Voss et al., 2010).
T883 454-609 Sentence denotes However, a recent study demonstrated that TMZ-induced autophagy is pro-survival, and may block the eventual apoptosis in GBM cells (Knizhnik et al., 2013).
T19 454-609 Sentence denotes However, a recent study demonstrated that TMZ-induced autophagy is pro-survival, and may block the eventual apoptosis in GBM cells (Knizhnik et al., 2013).
T884 610-724 Sentence denotes Also, MAPO2 (C1orf201) gene participates in the O6-methylguanine lesion-induced apoptosis (Fujikane et al., 2012).
T20 610-724 Sentence denotes Also, MAPO2 (C1orf201) gene participates in the O6-methylguanine lesion-induced apoptosis (Fujikane et al., 2012).
T885 725-767 Sentence denotes MAPO2 gene encodes a novel 37-kDa protein.
T21 725-767 Sentence denotes MAPO2 gene encodes a novel 37-kDa protein.
T886 768-832 Sentence denotes It is not determined whether this gene is involved in autophagy.
T22 768-832 Sentence denotes It is not determined whether this gene is involved in autophagy.