Id |
Subject |
Object |
Predicate |
Lexical cue |
T880 |
0-160 |
Sentence |
denotes |
Temozolomide induces generation of DNA lesions, including O6-methylguanine, N3-methyladenine, and N7-methylguanine (Goellner et al., 2011; Zhang et al., 2012b). |
T16 |
0-160 |
Sentence |
denotes |
Temozolomide induces generation of DNA lesions, including O6-methylguanine, N3-methyladenine, and N7-methylguanine (Goellner et al., 2011; Zhang et al., 2012b). |
T881 |
161-286 |
Sentence |
denotes |
The O6-methylguanine lesion is known to trigger autophagy, rather than apoptosis, to cause cell death (Kanzawa et al., 2003). |
T17 |
161-286 |
Sentence |
denotes |
The O6-methylguanine lesion is known to trigger autophagy, rather than apoptosis, to cause cell death (Kanzawa et al., 2003). |
T882 |
287-453 |
Sentence |
denotes |
Also, inhibition of antiapoptotic Bcl-2 by a pan-Bcl-2 inhibitor (−)-gossypol leads to autophagic death in gliomas and enhances the action of TMZ (Voss et al., 2010). |
T18 |
287-453 |
Sentence |
denotes |
Also, inhibition of antiapoptotic Bcl-2 by a pan-Bcl-2 inhibitor (−)-gossypol leads to autophagic death in gliomas and enhances the action of TMZ (Voss et al., 2010). |
T883 |
454-609 |
Sentence |
denotes |
However, a recent study demonstrated that TMZ-induced autophagy is pro-survival, and may block the eventual apoptosis in GBM cells (Knizhnik et al., 2013). |
T19 |
454-609 |
Sentence |
denotes |
However, a recent study demonstrated that TMZ-induced autophagy is pro-survival, and may block the eventual apoptosis in GBM cells (Knizhnik et al., 2013). |
T884 |
610-724 |
Sentence |
denotes |
Also, MAPO2 (C1orf201) gene participates in the O6-methylguanine lesion-induced apoptosis (Fujikane et al., 2012). |
T20 |
610-724 |
Sentence |
denotes |
Also, MAPO2 (C1orf201) gene participates in the O6-methylguanine lesion-induced apoptosis (Fujikane et al., 2012). |
T885 |
725-767 |
Sentence |
denotes |
MAPO2 gene encodes a novel 37-kDa protein. |
T21 |
725-767 |
Sentence |
denotes |
MAPO2 gene encodes a novel 37-kDa protein. |
T886 |
768-832 |
Sentence |
denotes |
It is not determined whether this gene is involved in autophagy. |
T22 |
768-832 |
Sentence |
denotes |
It is not determined whether this gene is involved in autophagy. |