Id |
Subject |
Object |
Predicate |
Lexical cue |
S1 |
0-102 |
Sentence |
denotes |
Photoaffinity labeling of plasma membrane receptors for aldosterone from human mononuclear leukocytes. |
S2 |
103-278 |
Sentence |
denotes |
Non-genomic effects of aldosterone on the sodium-proton-antiport have been shown in human mononuclear leukocytes which could be related to a new aldosterone membrane receptor. |
S3 |
279-417 |
Sentence |
denotes |
In the present paper plasma membranes from human mononuclear leukocytes were covalently photolabeled with a [125I]-aldosterone derivative. |
S4 |
418-654 |
Sentence |
denotes |
Sodium dodecyl sulfate-polyacrylamide gel electrophoresis showed significant aldosterone binding at a molecular weight of approximately 50000 Dalton which was absent with 1 microM cold aldosterone, but not cortisol in the binding media. |
S5 |
655-820 |
Sentence |
denotes |
The presence of the sulfhydryl agent dithiothreitol did not affect results suggesting the absence of disulfide bridges in the steroid binding domain of the receptor. |
S6 |
821-918 |
Sentence |
denotes |
These data are the first to define the molecular weight of the membrane receptor for aldosterone. |