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PMC:3312845 / 31396-32730 JSONTXT 24 Projects

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Id Subject Object Predicate Lexical cue
T12413 0-2 IN denotes In
T12414 3-6 PRP-DOLLAR- denotes our
T12415 7-15 JJ denotes previous
T12416 16-23 NN denotes studies
T12417 24-25 -LRB- denotes [
T12418 25-28 CD denotes 5,8
T12419 28-29 -RRB- denotes ]
T12420 29-30 -COMMA- denotes ,
T12421 31-41 NN denotes dystrophin
T12422 42-43 -LRB- denotes (
T12423 43-45 DT denotes an
T12424 46-59 JJ denotes actin-binding
T12425 60-67 NN denotes protein
T12426 68-69 -LRB- denotes [
T12427 69-71 CD denotes 40
T12428 71-72 -RRB- denotes ]
T12429 72-73 -RRB- denotes )
T12430 74-90 NN denotes immunoreactivity
T12431 91-94 VB denotes was
T12432 95-103 VB denotes detected
T12433 104-106 IN denotes in
T12434 107-112 NN denotes blood
T12435 113-120 NN denotes vessels
T12436 121-124 CC denotes and
T12437 125-127 IN denotes in
T12438 128-138 JJ denotes astrocytic
T12439 139-151 JJ denotes perivascular
T12440 152-160 NN denotes end-feet
T12441 160-161 -COMMA- denotes ,
T12442 162-165 CC denotes and
T12443 166-169 VB denotes was
T12444 170-184 VB denotes down-regulated
T12445 185-187 CD denotes 12
T12446 188-191 NN denotes hrs
T12447 192-197 IN denotes after
T12448 198-200 NN denotes SE
T12449 201-206 JJ denotes prior
T12450 207-209 TO denotes to
T12451 210-213 DT denotes the
T12452 214-224 NN denotes appearance
T12453 225-227 IN denotes of
T12454 228-237 JJ denotes vasogenic
T12455 238-243 NN denotes edema
T12456 244-247 CC denotes and
T12457 248-263 NN denotes down-regulation
T12458 264-266 IN denotes of
T12459 267-273 NN denotes SMI-71
T12460 274-290 NN denotes immunoreactivity
T12461 292-296 IN denotes With
T12462 297-304 NN denotes respect
T12463 305-307 TO denotes to
T12464 308-312 DT denotes this
T12465 313-321 JJ denotes previous
T12466 322-328 NN denotes report
T12467 328-329 -COMMA- denotes ,
T12468 330-337 NN denotes changes
T12469 338-340 IN denotes in
T12470 341-344 NN denotes SMI
T12471 345-361 NN denotes immunoreactivity
T12472 362-367 MD denotes would
T12473 368-370 VB denotes be
T12474 371-385 NN denotes causes/results
T12475 386-388 IN denotes of
T12476 389-400 NN denotes interaction
T12477 401-408 IN denotes between
T12478 409-420 JJ denotes endothelial
T12479 421-426 NN denotes cells
T12480 427-430 CC denotes and
T12481 431-443 JJ denotes perivascular
T12482 444-454 NN denotes astrocytes
T12483 456-458 IN denotes In
T12484 459-462 DT denotes the
T12485 463-470 JJ denotes present
T12486 471-476 NN denotes study
T12487 476-477 -COMMA- denotes ,
T12488 478-488 NN denotes p65-Ser276
T12489 488-489 -COMMA- denotes ,
T12490 490-500 NN denotes p65-Ser311
T12491 500-501 -COMMA- denotes ,
T12492 502-512 NN denotes p65-Ser529
T12493 512-513 -COMMA- denotes ,
T12494 514-517 CC denotes and
T12495 518-528 NN denotes p65-Ser536
T12496 529-544 NN denotes phosphorylation
T12497 545-548 VB denotes was
T12498 549-557 VB denotes observed
T12499 558-560 IN denotes in
T12500 561-571 NN denotes astrocytes
T12501 572-581 VB denotes following
T12502 582-584 NN denotes SE
T12503 586-597 RB denotes Furthermore
T12504 597-598 -COMMA- denotes ,
T12505 599-607 NN denotes sTNFp55R
T12506 608-616 NN denotes infusion
T12507 617-628 RB denotes effectively
T12508 629-638 VB denotes inhibited
T12509 639-649 NN denotes p65-Ser276
T12510 650-653 CC denotes and
T12511 654-679 NN denotes p65-Ser311phosphorylation
T12512 680-682 IN denotes in
T12513 683-693 NN denotes astrocytes
T12514 694-703 VB denotes following
T12515 704-706 NN denotes SE
T12516 708-717 RB denotes Therefore
T12517 717-718 -COMMA- denotes ,
T12518 719-721 PRP denotes it
T12519 722-724 VB denotes is
T12520 725-731 JJ denotes likely
T12521 732-736 IN denotes that
T12522 737-745 VB denotes enhanced
T12523 746-756 NN denotes p65-Ser276
T12524 757-760 CC denotes and
T12525 761-771 NN denotes p65-Ser311
T12526 772-787 NN denotes phosphorylation
T12527 788-791 MD denotes may
T12528 792-794 VB denotes be
T12529 795-803 VB denotes involved
T12530 804-806 IN denotes in
T12531 807-821 JJ denotes TNF-α-mediated
T12532 822-825 NN denotes BBB
T12533 826-836 NN denotes disruption
T12534 838-845 RB denotes However
T12535 845-846 -COMMA- denotes ,
T12536 847-855 NN denotes sTNFp55R
T12537 856-864 NN denotes infusion
T12538 865-870 MD denotes could
T12539 871-874 RB denotes not
T12540 875-882 VB denotes prevent
T12541 883-893 NN denotes p65-Ser529
T12542 894-897 CC denotes and
T12543 898-908 NN denotes p65-Ser536
T12544 909-925 NN denotes phosphorylations
T12545 926-930 IN denotes from
T12546 931-933 NN denotes SE
T12547 934-941 NN denotes insults
T12548 943-948 IN denotes Since
T12549 949-959 NN denotes p65-Ser529
T12550 960-963 CC denotes and
T12551 964-974 NN denotes p65-Ser536
T12552 975-978 VB denotes are
T12553 979-993 VB denotes phosphorylated
T12554 994-996 IN denotes by
T12555 997-1002 NN denotes TNF-α
T12556 1003-1006 CC denotes and
T12557 1007-1012 NN denotes IL-1β
T12558 1013-1014 -LRB- denotes [
T12559 1014-1016 CD denotes 41
T12560 1016-1017 -RRB- denotes ]
T12561 1017-1018 -COMMA- denotes ,
T12562 1019-1021 PRP denotes it
T12563 1022-1024 VB denotes is
T12564 1025-1031 JJ denotes likely
T12565 1032-1036 IN denotes that
T12566 1037-1051 JJ denotes IL-1β-mediated
T12567 1052-1069 NN denotes p65-Ser529/Ser536
T12568 1070-1085 NN denotes phosphorylation
T12569 1086-1089 MD denotes may
T12570 1090-1094 RB denotes also
T12571 1095-1099 VB denotes play
T12572 1100-1101 DT denotes a
T12573 1102-1106 NN denotes role
T12574 1107-1109 IN denotes in
T12575 1110-1120 JJ denotes SE-induced
T12576 1121-1130 JJ denotes vasogenic
T12577 1131-1136 NN denotes edema
T12578 1138-1147 RB denotes Therefore
T12579 1147-1148 -COMMA- denotes ,
T12580 1149-1152 PRP-DOLLAR- denotes our
T12581 1153-1161 NN denotes findings
T12582 1162-1170 VB denotes indicate
T12583 1171-1175 IN denotes that
T12584 1176-1180 CC denotes both
T12585 1181-1186 NN denotes TNF-α
T12586 1187-1190 CC denotes and
T12587 1191-1196 NN denotes IL-1β
T12588 1197-1200 MD denotes may
T12589 1201-1203 VB denotes be
T12590 1204-1214 NN denotes synergists
T12591 1215-1217 TO denotes to
T12592 1218-1222 VB denotes play
T12593 1223-1229 CC denotes either
T12594 1230-1231 DT denotes a
T12595 1232-1238 JJ denotes direct
T12596 1239-1240 -LRB- denotes (
T12597 1240-1242 IN denotes by
T12598 1243-1254 JJ denotes endothelial
T12599 1255-1260 NN denotes cells
T12600 1260-1261 -RRB- denotes )
T12601 1262-1264 CC denotes or
T12602 1265-1273 JJ denotes indirect
T12603 1274-1275 -LRB- denotes (
T12604 1275-1277 IN denotes by
T12605 1278-1288 NN denotes astrocytes
T12606 1288-1289 -RRB- denotes )
T12607 1290-1294 NN denotes role
T12608 1295-1297 IN denotes in
T12609 1298-1301 DT denotes the
T12610 1302-1313 NN denotes maintenance
T12611 1314-1316 IN denotes of
T12612 1317-1320 NN denotes BBB
T12613 1321-1333 NN denotes permeability
R9663 T12416 T12413 arg2Of studies,In
R9664 T12416 T12414 arg1Of studies,our
R9665 T12416 T12415 arg1Of studies,previous
R9666 T12416 T12417 arg1Of studies,[
R9667 T12418 T12417 arg2Of "5,8",[
R9668 T12419 T12417 arg3Of ],[
R9669 T12421 T12422 arg1Of dystrophin,(
R9670 T12425 T12422 arg2Of protein,(
R9671 T12425 T12423 arg1Of protein,an
R9672 T12425 T12424 arg1Of protein,actin-binding
R9673 T12425 T12426 arg1Of protein,[
R9674 T12427 T12426 arg2Of 40,[
R9675 T12428 T12426 arg3Of ],[
R9676 T12429 T12422 arg3Of ),(
R9677 T12430 T12421 arg1Of immunoreactivity,dystrophin
R9678 T12430 T12431 arg1Of immunoreactivity,was
R9679 T12430 T12432 arg2Of immunoreactivity,detected
R9680 T12430 T12443 arg1Of immunoreactivity,was
R9681 T12432 T12431 arg2Of detected,was
R9682 T12432 T12433 arg1Of detected,in
R9683 T12432 T12437 arg1Of detected,in
R9684 T12432 T12442 arg1Of detected,and
R9685 T12433 T12436 arg1Of in,and
R9686 T12435 T12433 arg2Of vessels,in
R9687 T12435 T12434 arg1Of vessels,blood
R9688 T12437 T12436 arg2Of in,and
R9689 T12440 T12437 arg2Of end-feet,in
R9690 T12440 T12438 arg1Of end-feet,astrocytic
R9691 T12440 T12439 arg1Of end-feet,perivascular
R9692 T12442 T12413 arg1Of and,In
R9693 T12442 T12420 arg1Of and,","
R9694 T12442 T12441 arg1Of and,","
R9695 T12443 T12442 arg2Of was,and
R9696 T12443 T12447 arg1Of was,after
R9697 T12446 T12443 arg2Of hrs,was
R9698 T12446 T12444 arg2Of hrs,down-regulated
R9699 T12446 T12445 arg1Of hrs,12
R9700 T12448 T12447 arg2Of SE,after
R9701 T12448 T12449 arg1Of SE,prior
R9702 T12449 T12450 arg1Of prior,to
R9703 T12452 T12450 arg2Of appearance,to
R9704 T12452 T12451 arg1Of appearance,the
R9705 T12452 T12453 arg1Of appearance,of
R9706 T12455 T12454 arg1Of edema,vasogenic
R9707 T12455 T12456 arg1Of edema,and
R9708 T12456 T12453 arg2Of and,of
R9709 T12457 T12456 arg2Of down-regulation,and
R9710 T12457 T12458 arg1Of down-regulation,of
R9711 T12460 T12458 arg2Of immunoreactivity,of
R9712 T12460 T12459 arg1Of immunoreactivity,SMI-71
R9713 T12461 T12463 arg1Of With,to
R9714 T12462 T12461 arg2Of respect,With
R9715 T12466 T12461 arg3Of report,With
R9716 T12466 T12464 arg1Of report,this
R9717 T12466 T12465 arg1Of report,previous
R9718 T12468 T12469 arg1Of changes,in
R9719 T12468 T12472 arg1Of changes,would
R9720 T12468 T12473 arg1Of changes,be
R9721 T12471 T12469 arg2Of immunoreactivity,in
R9722 T12471 T12470 arg1Of immunoreactivity,SMI
R9723 T12473 T12461 arg1Of be,With
R9724 T12473 T12467 arg1Of be,","
R9725 T12473 T12472 arg2Of be,would
R9726 T12474 T12473 arg2Of causes/results,be
R9727 T12474 T12475 arg1Of causes/results,of
R9728 T12474 T12477 arg1Of causes/results,between
R9729 T12476 T12475 arg2Of interaction,of
R9730 T12479 T12478 arg1Of cells,endothelial
R9731 T12479 T12480 arg1Of cells,and
R9732 T12480 T12477 arg2Of and,between
R9733 T12482 T12480 arg2Of astrocytes,and
R9734 T12482 T12481 arg1Of astrocytes,perivascular
R9735 T12486 T12483 arg2Of study,In
R9736 T12486 T12484 arg1Of study,the
R9737 T12486 T12485 arg1Of study,present
R9738 T12488 T12489 arg1Of p65-Ser276,","
R9739 T12489 T12491 arg1Of ",",","
R9740 T12490 T12489 arg2Of p65-Ser311,","
R9741 T12491 T12494 arg1Of ",",and
R9742 T12492 T12491 arg2Of p65-Ser529,","
R9743 T12494 T12493 arg1Of and,","
R9744 T12494 T12497 arg1Of and,was
R9745 T12494 T12498 arg2Of and,observed
R9746 T12496 T12494 arg2Of phosphorylation,and
R9747 T12496 T12495 arg1Of phosphorylation,p65-Ser536
R9748 T12498 T12483 arg1Of observed,In
R9749 T12498 T12487 arg1Of observed,","
R9750 T12498 T12497 arg2Of observed,was
R9751 T12498 T12499 arg1Of observed,in
R9752 T12498 T12501 arg1Of observed,following
R9753 T12500 T12499 arg2Of astrocytes,in
R9754 T12502 T12501 arg2Of SE,following
R9755 T12506 T12505 arg1Of infusion,sTNFp55R
R9756 T12506 T12508 arg1Of infusion,inhibited
R9757 T12508 T12503 arg1Of inhibited,Furthermore
R9758 T12508 T12504 arg1Of inhibited,","
R9759 T12508 T12507 arg1Of inhibited,effectively
R9760 T12508 T12514 arg1Of inhibited,following
R9761 T12509 T12510 arg1Of p65-Ser276,and
R9762 T12510 T12508 arg2Of and,inhibited
R9763 T12510 T12512 arg1Of and,in
R9764 T12511 T12510 arg2Of p65-Ser311phosphorylation,and
R9765 T12513 T12512 arg2Of astrocytes,in
R9766 T12515 T12514 arg2Of SE,following
R9767 T12518 T12519 arg1Of it,is
R9768 T12518 T12520 arg1Of it,likely
R9769 T12519 T12516 arg1Of is,Therefore
R9770 T12519 T12517 arg1Of is,","
R9771 T12520 T12519 arg2Of likely,is
R9772 T12523 T12522 arg2Of p65-Ser276,enhanced
R9773 T12523 T12524 arg1Of p65-Ser276,and
R9774 T12524 T12527 arg1Of and,may
R9775 T12524 T12528 arg1Of and,be
R9776 T12524 T12529 arg2Of and,involved
R9777 T12526 T12524 arg2Of phosphorylation,and
R9778 T12526 T12525 arg1Of phosphorylation,p65-Ser311
R9779 T12529 T12520 arg2Of involved,likely
R9780 T12529 T12521 arg1Of involved,that
R9781 T12529 T12527 arg2Of involved,may
R9782 T12529 T12528 arg2Of involved,be
R9783 T12529 T12530 arg1Of involved,in
R9784 T12533 T12530 arg2Of disruption,in
R9785 T12533 T12531 arg1Of disruption,TNF-α-mediated
R9786 T12533 T12532 arg1Of disruption,BBB
R9787 T12537 T12536 arg1Of infusion,sTNFp55R
R9788 T12537 T12538 arg1Of infusion,could
R9789 T12537 T12540 arg1Of infusion,prevent
R9790 T12540 T12534 arg1Of prevent,However
R9791 T12540 T12535 arg1Of prevent,","
R9792 T12540 T12538 arg2Of prevent,could
R9793 T12540 T12539 arg1Of prevent,not
R9794 T12540 T12545 arg1Of prevent,from
R9795 T12541 T12542 arg1Of p65-Ser529,and
R9796 T12542 T12540 arg2Of and,prevent
R9797 T12544 T12542 arg2Of phosphorylations,and
R9798 T12544 T12543 arg1Of phosphorylations,p65-Ser536
R9799 T12547 T12545 arg2Of insults,from
R9800 T12547 T12546 arg1Of insults,SE
R9801 T12549 T12550 arg1Of p65-Ser529,and
R9802 T12550 T12552 arg1Of and,are
R9803 T12550 T12553 arg2Of and,phosphorylated
R9804 T12551 T12550 arg2Of p65-Ser536,and
R9805 T12553 T12548 arg2Of phosphorylated,Since
R9806 T12553 T12552 arg2Of phosphorylated,are
R9807 T12555 T12556 arg1Of TNF-α,and
R9808 T12556 T12553 arg1Of and,phosphorylated
R9809 T12556 T12554 arg2Of and,by
R9810 T12557 T12556 arg2Of IL-1β,and
R9811 T12557 T12558 arg1Of IL-1β,[
R9812 T12559 T12558 arg2Of 41,[
R9813 T12560 T12558 arg3Of ],[
R9814 T12562 T12563 arg1Of it,is
R9815 T12562 T12564 arg1Of it,likely
R9816 T12563 T12548 arg1Of is,Since
R9817 T12563 T12561 arg1Of is,","
R9818 T12564 T12563 arg2Of likely,is
R9819 T12568 T12566 arg1Of phosphorylation,IL-1β-mediated
R9820 T12568 T12567 arg1Of phosphorylation,p65-Ser529/Ser536
R9821 T12568 T12569 arg1Of phosphorylation,may
R9822 T12568 T12571 arg1Of phosphorylation,play
R9823 T12571 T12564 arg2Of play,likely
R9824 T12571 T12565 arg1Of play,that
R9825 T12571 T12569 arg2Of play,may
R9826 T12571 T12570 arg1Of play,also
R9827 T12571 T12574 arg1Of play,in
R9828 T12573 T12571 arg2Of role,play
R9829 T12573 T12572 arg1Of role,a
R9830 T12577 T12574 arg2Of edema,in
R9831 T12577 T12575 arg1Of edema,SE-induced
R9832 T12577 T12576 arg1Of edema,vasogenic
R9833 T12581 T12580 arg1Of findings,our
R9834 T12581 T12582 arg1Of findings,indicate
R9835 T12582 T12578 arg1Of indicate,Therefore
R9836 T12582 T12579 arg1Of indicate,","
R9837 T12585 T12586 arg1Of TNF-α,and
R9838 T12586 T12584 arg1Of and,both
R9839 T12586 T12588 arg1Of and,may
R9840 T12586 T12589 arg1Of and,be
R9841 T12587 T12586 arg2Of IL-1β,and
R9842 T12589 T12582 arg2Of be,indicate
R9843 T12589 T12583 arg1Of be,that
R9844 T12589 T12588 arg2Of be,may
R9845 T12590 T12589 arg2Of synergists,be
R9846 T12590 T12591 modOf synergists,to
R9847 T12592 T12591 arg1Of play,to
R9848 T12592 T12593 arg1Of play,either
R9849 T12592 T12603 arg1Of play,(
R9850 T12592 T12608 arg1Of play,in
R9851 T12599 T12595 arg1Of cells,direct
R9852 T12599 T12596 arg2Of cells,(
R9853 T12599 T12597 arg1Of cells,by
R9854 T12599 T12598 arg1Of cells,endothelial
R9855 T12599 T12601 arg1Of cells,or
R9856 T12600 T12596 arg3Of ),(
R9857 T12601 T12593 arg2Of or,either
R9858 T12601 T12594 arg1Of or,a
R9859 T12602 T12601 arg2Of indirect,or
R9860 T12604 T12603 arg2Of by,(
R9861 T12605 T12604 arg2Of astrocytes,by
R9862 T12606 T12603 arg3Of ),(
R9863 T12607 T12592 arg2Of role,play
R9864 T12610 T12608 arg2Of maintenance,in
R9865 T12610 T12609 arg1Of maintenance,the
R9866 T12610 T12611 arg1Of maintenance,of
R9867 T12613 T12611 arg2Of permeability,of
R9868 T12613 T12612 arg1Of permeability,BBB