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PMC:1920263 JSONTXT 24 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T76 0-3 NN denotes Sp1
T11426 0-3 NN denotes Sp1
T77 4-7 CC denotes and
T11427 4-7 CC denotes and
T78 8-11 NN denotes Sp3
T11428 8-11 NN denotes Sp3
T79 12-20 VB denotes regulate
T80 21-26 JJ denotes basal
T81 27-40 NN denotes transcription
T11429 27-40 NN denotes transcription
T82 41-43 IN denotes of
T83 44-47 DT denotes the
T84 48-53 JJ denotes human
T85 54-62 NN denotes APOBEC3G
T86 63-67 NN denotes gene
T87 79-87 NN denotes APOBEC3G
T88 88-89 -LRB- denotes (
T89 89-92 NN denotes A3G
T90 92-93 -RRB- denotes )
T91 93-94 -COMMA- denotes ,
T92 95-96 DT denotes a
T93 97-103 NN denotes member
T94 104-106 IN denotes of
T95 107-110 DT denotes the
T96 111-119 RB denotes recently
T97 120-130 VB denotes discovered
T98 131-137 NN denotes family
T99 138-140 IN denotes of
T100 141-146 JJ denotes human
T101 147-155 NN denotes cytidine
T102 156-166 NN denotes deaminases
T103 166-167 -COMMA- denotes ,
T104 168-170 VB denotes is
T105 171-180 VB denotes expressed
T106 181-183 IN denotes in
T107 184-194 JJ denotes peripheral
T108 195-200 NN denotes blood
T109 201-212 NN denotes lymphocytes
T110 213-216 CC denotes and
T111 217-220 VB denotes has
T112 221-225 VB denotes been
T113 226-231 VB denotes shown
T114 232-234 TO denotes to
T115 235-237 VB denotes be
T116 238-244 JJ denotes active
T117 245-252 IN denotes against
T118 253-258 NN denotes HIV-1
T119 259-262 CC denotes and
T120 263-268 JJ denotes other
T121 269-281 NN denotes retroviruses
T122 283-285 TO denotes To
T123 286-290 VB denotes gain
T124 291-294 JJ denotes new
T125 295-303 NN denotes insights
T126 304-308 IN denotes into
T127 309-312 DT denotes the
T128 313-328 JJ denotes transcriptional
T129 329-339 NN denotes regulation
T130 340-342 IN denotes of
T131 343-347 DT denotes this
T132 348-359 NN denotes restriction
T133 360-366 NN denotes factor
T134 366-367 -COMMA- denotes ,
T135 368-370 PRP denotes we
T136 371-377 VB denotes cloned
T137 378-381 CC denotes and
T138 382-395 VB denotes characterized
T139 396-399 DT denotes the
T140 400-408 NN denotes promoter
T141 409-415 NN denotes region
T142 416-418 IN denotes of
T143 419-422 NN denotes A3G
T144 424-439 JJ denotes Transcriptional
T145 440-445 NN denotes start
T146 446-451 NN denotes sites
T147 452-456 VB denotes were
T148 457-467 VB denotes identified
T149 468-470 IN denotes by
T150 471-479 JJ denotes 5′-rapid
T151 480-493 NN denotes amplification
T152 494-496 IN denotes of
T153 497-501 NN denotes cDNA
T154 502-506 VB denotes ends
T155 507-515 NN denotes analysis
T156 517-527 NN denotes Luciferase
T157 528-536 NN denotes reporter
T158 537-543 NN denotes assays
T159 544-556 VB denotes demonstrated
T160 557-561 IN denotes that
T161 562-563 DT denotes a
T162 564-571 NN denotes 1025 bp
T163 572-575 NN denotes A3G
T164 576-584 NN denotes promoter
T165 585-593 NN denotes sequence
T166 594-595 -LRB- denotes (
T167 595-599 IN denotes from
T168 600-604 CD denotes −959
T169 605-607 TO denotes to
T170 608-611 CD denotes +66
T171 612-620 JJ denotes relative
T172 621-623 TO denotes to
T173 624-627 DT denotes the
T174 628-633 JJ denotes major
T175 634-649 JJ denotes transcriptional
T176 650-655 NN denotes start
T177 656-660 NN denotes site
T178 660-661 -RRB- denotes )
T179 662-671 VB denotes displayed
T180 672-684 JJ denotes constitutive
T181 685-693 NN denotes promoter
T182 694-702 NN denotes activity
T183 704-706 IN denotes In
T184 707-708 NN denotes T
T185 709-714 NN denotes cells
T186 714-715 -COMMA- denotes ,
T187 716-719 DT denotes the
T188 720-723 NN denotes A3G
T189 724-732 NN denotes promoter
T190 733-736 VB denotes was
T191 737-740 RB denotes not
T192 741-750 JJ denotes inducible
T193 751-753 IN denotes by
T194 754-763 JJ denotes mitogenic
T195 764-775 NN denotes stimulation
T196 775-776 -COMMA- denotes ,
T197 777-787 NN denotes interferon
T198 788-797 NN denotes treatment
T199 798-800 CC denotes or
T200 801-811 NN denotes expression
T201 812-814 IN denotes of
T202 815-820 NN denotes HIV-1
T203 821-829 NN denotes proteins
T204 831-836 VB denotes Using
T205 837-838 DT denotes a
T206 839-845 NN denotes series
T207 846-848 IN denotes of
T208 849-851 NN denotes 5′
T209 852-860 NN denotes deletion
T210 861-869 NN denotes promoter
T211 870-880 NN denotes constructs
T212 881-883 IN denotes in
T213 884-894 NN denotes luciferase
T214 895-903 NN denotes reporter
T215 904-910 NN denotes assays
T216 910-911 -COMMA- denotes ,
T217 912-914 PRP denotes we
T218 915-925 VB denotes identified
T219 926-927 DT denotes a
T220 928-934 NN denotes 180 bp
T221 935-941 NN denotes region
T222 942-946 WDT denotes that
T223 947-950 VB denotes was
T224 951-961 JJ denotes sufficient
T225 962-965 IN denotes for
T226 966-970 JJ denotes full
T227 971-979 NN denotes promoter
T228 980-988 NN denotes activity
T229 990-1005 JJ denotes Transcriptional
T230 1006-1014 NN denotes activity
T231 1015-1017 IN denotes of
T232 1018-1022 DT denotes this
T233 1023-1026 NN denotes A3G
T234 1027-1031 NN denotes core
T235 1032-1040 NN denotes promoter
T236 1041-1044 VB denotes was
T237 1045-1054 JJ denotes dependent
T238 1055-1057 IN denotes on
T239 1058-1059 DT denotes a
T240 1060-1066 NN denotes GC-box
T241 1067-1068 -LRB- denotes (
T242 1068-1075 JJ denotes located
T243 1076-1078 IN denotes at
T244 1079-1087 NN denotes position
T245 1088-1095 NN denotes −87/−78
T246 1096-1104 JJ denotes relative
T247 1105-1107 TO denotes to
T248 1108-1111 DT denotes the
T249 1112-1117 JJ denotes major
T250 1118-1133 JJ denotes transcriptional
T251 1134-1139 NN denotes start
T252 1140-1144 NN denotes site
T253 1144-1145 -RRB- denotes )
T254 1146-1149 CC denotes and
T255 1150-1153 VB denotes was
T256 1154-1163 VB denotes abolished
T257 1164-1169 IN denotes after
T258 1170-1178 NN denotes mutation
T259 1179-1181 IN denotes of
T260 1182-1186 DT denotes this
T261 1187-1190 NN denotes DNA
T262 1191-1198 NN denotes element
T263 1200-1215 JJ denotes Electrophoretic
T264 1216-1224 NN denotes mobility
T265 1225-1230 NN denotes shift
T266 1231-1237 NN denotes assays
T267 1238-1241 CC denotes and
T268 1242-1251 NN denotes chromatin
T269 1252-1271 NN denotes immunoprecipitation
T270 1272-1278 NN denotes assays
T271 1279-1291 VB denotes demonstrated
T272 1292-1296 IN denotes that
T273 1297-1300 DT denotes the
T274 1301-1311 VB denotes identified
T275 1312-1318 NN denotes GC-box
T276 1319-1330 VB denotes represented
T277 1331-1332 DT denotes a
T278 1333-1340 VB denotes binding
T279 1341-1345 NN denotes site
T280 1346-1349 IN denotes for
T281 1350-1353 DT denotes the
T282 1354-1364 JJ denotes ubiquitous
T283 1365-1378 NN denotes transcription
T284 1379-1386 NN denotes factors
T11430 1379-1386 NN denotes factors
T285 1387-1398 NN denotes specificity
T286 1399-1406 NN denotes protein
T287 1407-1408 -LRB- denotes (
T288 1408-1410 NN denotes Sp
T289 1410-1411 -RRB- denotes )
T290 1412-1413 CD denotes 1
T291 1414-1417 CC denotes and
T292 1418-1421 NN denotes Sp3
T881 1437-1440 DT denotes The
T882 1441-1449 RB denotes recently
T883 1450-1460 VB denotes discovered
T884 1461-1468 NN denotes APOBEC3
T885 1469-1475 NN denotes family
T886 1476-1478 IN denotes of
T887 1479-1487 NN denotes cytidine
T888 1488-1498 NN denotes deaminases
T889 1499-1501 VB denotes is
T890 1502-1512 VB denotes considered
T891 1513-1515 TO denotes to
T892 1516-1520 VB denotes play
T893 1521-1523 DT denotes an
T894 1524-1533 JJ denotes important
T895 1534-1538 NN denotes role
T896 1539-1541 IN denotes in
T897 1542-1551 JJ denotes antiviral
T898 1552-1561 JJ denotes intrinsic
T899 1562-1570 NN denotes immunity
T900 1571-1572 -LRB- denotes (
T901 1572-1575 CD denotes 1,2
T902 1575-1576 -RRB- denotes )
T903 1578-1580 IN denotes In
T904 1581-1589 NN denotes primates
T905 1589-1590 -COMMA- denotes ,
T906 1591-1594 DT denotes the
T907 1595-1600 CD denotes seven
T908 1601-1609 NN denotes paralogs
T909 1610-1618 NN denotes APOBEC3A
T910 1618-1619 -COMMA- denotes ,
T911 1620-1621 NN denotes B
T912 1621-1622 -COMMA- denotes ,
T913 1623-1624 NN denotes C
T914 1624-1625 -COMMA- denotes ,
T915 1626-1628 NNP denotes DE
T916 1628-1629 -COMMA- denotes ,
T917 1630-1631 NN denotes F
T918 1631-1632 -COMMA- denotes ,
T919 1633-1634 NN denotes G
T920 1634-1635 -COMMA- denotes ,
T921 1636-1637 NN denotes H
T922 1638-1639 -LRB- denotes (
T923 1639-1644 NN denotes A3A-H
T924 1644-1645 -RRB- denotes )
T925 1646-1650 VB denotes have
T926 1651-1655 VB denotes been
T927 1656-1665 VB denotes described
T928 1666-1667 -LRB- denotes (
T929 1667-1668 CD denotes 3
T930 1668-1669 -RRB- denotes )
T931 1669-1670 -COMMA- denotes ,
T932 1671-1674 CC denotes and
T933 1675-1679 PRP denotes they
T934 1680-1686 VB denotes appear
T935 1687-1689 TO denotes to
T936 1690-1697 VB denotes fulfill
T937 1698-1708 JJ denotes individual
T938 1709-1718 NN denotes functions
T939 1720-1725 JJ denotes Human
T940 1726-1734 NN denotes APOBEC3G
T941 1735-1736 -LRB- denotes (
T942 1736-1739 NN denotes A3G
T943 1739-1740 -RRB- denotes )
T944 1740-1741 -COMMA- denotes ,
T945 1742-1745 DT denotes the
T946 1746-1750 RB denotes most
T947 1751-1760 JJ denotes prominent
T948 1761-1767 NN denotes member
T949 1768-1770 IN denotes of
T950 1771-1774 DT denotes the
T951 1775-1782 NN denotes APOBEC3
T952 1783-1789 NN denotes family
T953 1790-1793 VB denotes has
T954 1794-1798 VB denotes been
T955 1799-1809 VB denotes identified
T956 1810-1812 IN denotes as
T957 1813-1816 DT denotes the
T958 1817-1825 JJ denotes cellular
T959 1826-1837 NN denotes restriction
T960 1838-1844 NN denotes factor
T961 1845-1849 WDT denotes that
T962 1850-1852 VB denotes is
T963 1853-1864 JJ denotes responsible
T964 1865-1868 IN denotes for
T965 1869-1879 NN denotes inhibition
T966 1880-1882 IN denotes of
T967 1883-1889 NN denotes virion
T968 1890-1901 NN denotes infectivity
T969 1902-1908 NN denotes factor
T970 1909-1910 -LRB- denotes (
T971 1910-1913 NN denotes Vif
T972 1913-1914 -RRB- denotes )
T973 1914-1922 JJ denotes -deleted
T974 1923-1928 JJ denotes human
T975 1929-1945 NN denotes immunodeficiency
T976 1946-1953 NN denotes virus-1
T977 1954-1955 -LRB- denotes (
T978 1955-1960 NN denotes HIV-1
T979 1960-1961 -RRB- denotes )
T980 1962-1973 NN denotes replication
T981 1974-1976 IN denotes in
T982 1977-1991 JJ denotes non-permissive
T983 1992-1997 NN denotes cells
T984 1998-1999 -LRB- denotes (
T985 1999-2000 CD denotes 4
T986 2000-2001 -RRB- denotes )
T987 2003-2006 NN denotes A3G
T988 2007-2009 VB denotes is
T989 2010-2018 VB denotes packaged
T990 2019-2023 IN denotes into
T991 2024-2033 NN denotes HIV-1Δvif
T992 2034-2043 NN denotes particles
T993 2044-2047 CC denotes and
T994 2048-2054 VB denotes causes
T995 2055-2061 NN denotes C-to-U
T996 2062-2074 NN denotes deaminations
T997 2075-2077 IN denotes on
T998 2078-2081 DT denotes the
T999 2082-2097 JJ denotes single-stranded
T1000 2098-2103 JJ denotes viral
T1001 2104-2107 NN denotes DNA
T1002 2108-2114 IN denotes during
T1003 2115-2122 JJ denotes reverse
T1004 2123-2136 NN denotes transcription
T1005 2137-2138 -LRB- denotes (
T1006 2138-2141 CD denotes 5–8
T1007 2141-2142 -RRB- denotes )
T1008 2144-2148 DT denotes This
T1009 2149-2154 VB denotes leads
T1010 2155-2157 TO denotes to
T1011 2158-2169 NN denotes degradation
T1012 2170-2172 IN denotes of
T1013 2173-2176 DT denotes the
T1014 2177-2195 JJ denotes uracile-containing
T1015 2196-2199 NN denotes DNA
T1016 2200-2202 IN denotes by
T1017 2203-2211 JJ denotes cellular
T1018 2212-2218 NN denotes repair
T1019 2219-2229 NN denotes mechanisms
T1020 2230-2232 CC denotes or
T1021 2233-2235 TO denotes to
T1022 2236-2249 NN denotes hypermutation
T1023 2250-2252 IN denotes of
T1024 2253-2256 DT denotes the
T1025 2257-2262 JJ denotes viral
T1026 2263-2269 NN denotes genome
T1027 2270-2271 -LRB- denotes (
T1028 2271-2274 CD denotes 5,6
T1029 2274-2275 -RRB- denotes )
T1030 2277-2279 IN denotes As
T1031 2280-2281 DT denotes a
T1032 2282-2288 NN denotes result
T1033 2288-2289 -COMMA- denotes ,
T1034 2290-2294 RB denotes only
T1035 2295-2296 DT denotes a
T1036 2297-2305 JJ denotes marginal
T1037 2306-2314 NN denotes fraction
T1038 2315-2317 IN denotes of
T1039 2318-2321 DT denotes the
T1040 2322-2336 JJ denotes A3G-containing
T1041 2337-2342 NN denotes HIV-1
T1042 2343-2352 NN denotes particles
T1043 2353-2355 VB denotes is
T1044 2356-2360 JJ denotes able
T1045 2361-2363 TO denotes to
T1046 2364-2372 VB denotes complete
T1047 2373-2376 DT denotes the
T1048 2377-2388 NN denotes replication
T1049 2389-2394 NN denotes cycle
T1050 2396-2398 IN denotes In
T1051 2399-2407 NN denotes addition
T1052 2408-2410 TO denotes to
T1053 2411-2414 DT denotes the
T1054 2415-2425 NN denotes inhibition
T1055 2426-2428 IN denotes of
T1056 2429-2434 NN denotes HIV-1
T1057 2434-2435 -COMMA- denotes ,
T1058 2436-2439 NN denotes A3G
T1059 2440-2449 VB denotes restricts
T1060 2450-2461 NN denotes replication
T1061 2462-2464 IN denotes of
T1062 2465-2470 JJ denotes other
T1063 2471-2483 NN denotes lentiviruses
T1064 2483-2484 -COMMA- denotes ,
T1065 2485-2502 NN denotes gammaretroviruses
T1066 2502-2503 -COMMA- denotes ,
T1067 2504-2521 NN denotes deltaretroviruses
T1068 2521-2522 -COMMA- denotes ,
T1069 2523-2535 NN denotes spumaviruses
T1070 2535-2536 -COMMA- denotes ,
T1071 2537-2557 NN denotes long-terminal-repeat
T1072 2558-2559 -LRB- denotes (
T1073 2559-2562 NN denotes LTR
T1074 2562-2563 -RRB- denotes )
T1075 2563-2580 NN denotes -retrotransposons
T1076 2580-2581 -COMMA- denotes ,
T1077 2582-2601 NN denotes orthohepadnaviruses
T1078 2602-2605 CC denotes and
T1079 2606-2623 NN denotes avihepadnaviruses
T1080 2624-2625 -LRB- denotes (
T1081 2625-2629 CD denotes 9–21
T1082 2629-2630 -RRB- denotes )
T1083 2632-2645 RB denotes Interestingly
T1084 2645-2646 -COMMA- denotes ,
T1085 2647-2658 NN denotes deamination
T1086 2659-2664 VB denotes seems
T1087 2665-2668 RB denotes not
T1088 2669-2671 TO denotes to
T1089 2672-2674 VB denotes be
T1090 2675-2678 DT denotes the
T1091 2679-2683 JJ denotes only
T1092 2684-2696 JJ denotes A3G-mediated
T1093 2697-2706 JJ denotes antiviral
T1094 2707-2716 NN denotes mechanism
T1095 2716-2717 -COLON- denotes ;
T1096 2718-2720 IN denotes in
T1097 2721-2724 DT denotes the
T1098 2725-2729 NN denotes case
T1099 2730-2732 IN denotes of
T1100 2733-2742 NN denotes hepatitis
T1101 2743-2744 NN denotes B
T1102 2745-2750 NN denotes virus
T1103 2751-2752 -LRB- denotes (
T1104 2752-2755 NN denotes HBV
T1105 2755-2756 -RRB- denotes )
T1106 2757-2760 CC denotes and
T1107 2761-2766 JJ denotes human
T1108 2767-2768 NN denotes T
T1109 2769-2773 NN denotes cell
T1110 2774-2782 NN denotes leukemia
T1111 2783-2788 NN denotes virus
T1112 2789-2793 NN denotes type
T1113 2794-2795 CD denotes 1
T1114 2796-2797 -LRB- denotes (
T1115 2797-2803 NN denotes HTLV-1
T1116 2803-2804 -RRB- denotes )
T1117 2804-2805 -COMMA- denotes ,
T1118 2806-2809 NN denotes A3G
T1119 2810-2813 VB denotes was
T1120 2814-2819 VB denotes shown
T1121 2820-2822 TO denotes to
T1122 2823-2831 VB denotes restrict
T1123 2832-2837 NN denotes virus
T1124 2838-2849 NN denotes replication
T1125 2850-2852 IN denotes by
T1126 2853-2876 JJ denotes deamination-independent
T1127 2877-2887 NN denotes mechanisms
T1128 2888-2889 -LRB- denotes (
T1129 2889-2891 CD denotes 12
T1130 2891-2892 -COMMA- denotes ,
T1131 2893-2895 CD denotes 13
T1132 2895-2896 -COMMA- denotes ,
T1133 2897-2899 CD denotes 19
T1134 2899-2900 -COMMA- denotes ,
T1135 2901-2906 CD denotes 22–25
T1136 2906-2907 -RRB- denotes )
T1137 2909-2916 DT denotes Another
T1138 2917-2923 NN denotes member
T1139 2924-2926 IN denotes of
T1140 2927-2930 DT denotes the
T1141 2931-2938 NN denotes APOBEC3
T1142 2939-2945 NN denotes family
T1143 2945-2946 -COMMA- denotes ,
T1144 2947-2955 NN denotes APOBEC3F
T1145 2956-2957 -LRB- denotes (
T1146 2957-2960 NN denotes A3F
T1147 2960-2961 -RRB- denotes )
T1148 2961-2962 -COMMA- denotes ,
T1149 2963-2970 VB denotes appears
T1150 2971-2973 TO denotes to
T1151 2974-2978 VB denotes have
T1152 2979-2986 JJ denotes similar
T1153 2987-2997 NN denotes activities
T1154 2998-3002 IN denotes like
T1155 3003-3006 NN denotes A3G
T1156 3007-3008 -LRB- denotes (
T1157 3008-3013 CD denotes 26,27
T1158 3013-3014 -RRB- denotes )
T1159 3016-3019 NN denotes A3F
T1160 3020-3022 VB denotes is
T1161 3023-3027 RB denotes also
T1162 3028-3036 VB denotes packaged
T1163 3037-3041 IN denotes into
T1164 3042-3051 NN denotes HIV-1Δvif
T1165 3052-3061 NN denotes particles
T1166 3062-3065 CC denotes and
T1167 3066-3073 VB denotes induces
T1168 3074-3081 JJ denotes similar
T1169 3082-3088 NN denotes C-to-U
T1170 3089-3101 NN denotes deaminations
T1171 3101-3102 -COMMA- denotes ,
T1172 3103-3111 IN denotes although
T1173 3112-3115 DT denotes the
T1174 3116-3124 NN denotes proteins
T1175 3125-3131 VB denotes differ
T1176 3132-3134 IN denotes in
T1177 3135-3140 PRP-DOLLAR- denotes their
T1178 3141-3147 NN denotes target
T1179 3148-3157 NN denotes sequences
T1180 3158-3169 NN denotes specificity
T1181 3170-3171 -LRB- denotes (
T1182 3171-3176 CD denotes 26,28
T1183 3176-3177 -RRB- denotes )
T1184 3179-3190 RB denotes Furthermore
T1185 3190-3191 -COMMA- denotes ,
T1186 3192-3195 NN denotes A3F
T1187 3196-3204 NN denotes proteins
T1188 3205-3209 VB denotes were
T1189 3210-3218 VB denotes detected
T1190 3219-3221 IN denotes in
T1191 3222-3226 JJ denotes many
T1192 3227-3234 NN denotes tissues
T1193 3235-3239 WDT denotes that
T1194 3240-3247 VB denotes express
T1195 3248-3251 NN denotes A3G
T1196 3252-3255 CC denotes and
T1197 3256-3259 VB denotes are
T1198 3260-3264 JJ denotes able
T1199 3265-3267 TO denotes to
T1200 3268-3272 VB denotes form
T1201 3273-3288 NN denotes heteromultimers
T1202 3289-3293 IN denotes with
T1203 3294-3297 NN denotes A3G
T1204 3298-3299 -LRB- denotes (
T1205 3299-3307 CD denotes 26,29,30
T1206 3307-3308 -RRB- denotes )
T1207 3310-3314 DT denotes Both
T1208 3315-3323 NN denotes proteins
T1209 3324-3332 VB denotes localize
T1210 3333-3335 TO denotes to
T1211 3336-3340 NN denotes mRNA
T1212 3341-3351 NN denotes processing
T1213 3352-3353 -LRB- denotes (
T1214 3353-3354 NN denotes P
T1215 3354-3355 -RRB- denotes )
T1216 3356-3362 NN denotes bodies
T1217 3362-3363 -COMMA- denotes ,
T1218 3364-3375 JJ denotes cytoplasmic
T1219 3376-3388 NN denotes compartments
T1220 3389-3397 VB denotes involved
T1221 3398-3400 IN denotes in
T1222 3401-3404 DT denotes the
T1223 3405-3416 NN denotes degradation
T1224 3417-3420 CC denotes and
T1225 3421-3428 NN denotes storage
T1226 3429-3431 IN denotes of
T1227 3432-3447 JJ denotes non-translating
T1228 3448-3453 NN denotes mRNAs
T1229 3454-3455 -LRB- denotes (
T1230 3455-3460 CD denotes 30,31
T1231 3460-3461 -RRB- denotes )
T1232 3463-3466 NN denotes A3G
T1233 3467-3470 VB denotes has
T1234 3471-3475 VB denotes been
T1235 3476-3481 VB denotes shown
T1236 3482-3484 TO denotes to
T1237 3485-3487 VB denotes be
T1238 3488-3497 VB denotes expressed
T1239 3498-3500 IN denotes in
T1240 3501-3502 NN denotes T
T1241 3503-3508 NN denotes cells
T1242 3508-3509 -COMMA- denotes ,
T1243 3510-3511 DT denotes a
T1244 3512-3520 JJ denotes relevant
T1245 3521-3525 NN denotes cell
T1246 3526-3532 NN denotes target
T1247 3533-3536 IN denotes for
T1248 3537-3542 NN denotes HIV-1
T1249 3543-3545 FW denotes in
T1250 3546-3550 FW denotes vivo
T1251 3550-3551 -COMMA- denotes ,
T1252 3552-3555 CC denotes but
T1253 3556-3562 JJ denotes little
T1254 3563-3565 VB denotes is
T1255 3566-3571 VB denotes known
T1256 3572-3577 IN denotes about
T1257 3578-3581 PRP-DOLLAR- denotes its
T1258 3582-3592 NN denotes regulation
T1259 3593-3594 -LRB- denotes (
T1260 3594-3601 CD denotes 4,29,32
T1261 3601-3602 -RRB- denotes )
T1262 3604-3609 EX denotes There
T1263 3610-3612 VB denotes is
T1264 3613-3614 DT denotes a
T1265 3615-3621 NN denotes report
T1266 3622-3632 VB denotes describing
T1267 3633-3637 IN denotes that
T1268 3638-3647 JJ denotes mitogenic
T1269 3648-3659 NN denotes stimulation
T1270 3660-3662 IN denotes of
T1271 3663-3664 NN denotes T
T1272 3665-3670 NN denotes cells
T1273 3671-3682 VB denotes upregulates
T1274 3683-3686 NN denotes A3G
T1275 3687-3691 NN denotes mRNA
T1276 3692-3698 NN denotes levels
T1277 3698-3699 -COMMA- denotes ,
T1278 3700-3703 CC denotes but
T1279 3704-3708 DT denotes this
T1280 3709-3712 VB denotes was
T1281 3713-3716 RB denotes not
T1282 3717-3725 VB denotes analyzed
T1283 3726-3728 IN denotes on
T1284 3729-3732 DT denotes the
T1285 3733-3748 JJ denotes transcriptional
T1286 3749-3754 NN denotes level
T1287 3755-3756 -LRB- denotes (
T1288 3756-3758 CD denotes 33
T1289 3758-3759 -RRB- denotes )
T1290 3761-3766 IN denotes Since
T1291 3767-3770 DT denotes the
T1292 3771-3774 NN denotes A3G
T1293 3775-3783 NN denotes promoter
T1294 3784-3787 VB denotes has
T1295 3788-3791 RB denotes not
T1296 3792-3796 VB denotes been
T1297 3797-3811 RB denotes systematically
T1298 3812-3820 VB denotes analyzed
T1299 3821-3823 RB denotes so
T1300 3824-3827 RB denotes far
T1301 3827-3828 -COMMA- denotes ,
T1302 3829-3832 PRP-DOLLAR- denotes our
T1303 3833-3836 NN denotes aim
T1304 3837-3840 VB denotes was
T1305 3841-3843 TO denotes to
T1306 3844-3849 VB denotes clone
T1307 3850-3853 DT denotes the
T1308 3854-3857 NN denotes A3G
T1309 3858-3866 NN denotes promoter
T1310 3867-3870 CC denotes and
T1311 3871-3883 VB denotes characterize
T1312 3884-3887 PRP-DOLLAR- denotes its
T1313 3888-3898 NN denotes regulation
T1314 3899-3901 IN denotes in
T1315 3902-3903 NN denotes T
T1316 3904-3909 NN denotes cells
T1317 3911-3913 IN denotes In
T1318 3914-3917 PRP-DOLLAR- denotes our
T1319 3918-3923 NN denotes study
T1320 3923-3924 -COMMA- denotes ,
T1321 3925-3927 PRP denotes we
T1322 3928-3936 VB denotes observed
T1323 3937-3941 IN denotes that
T1324 3942-3945 NN denotes A3G
T1325 3946-3950 VB denotes uses
T1326 3951-3959 JJ denotes multiple
T1327 3960-3975 JJ denotes transcriptional
T1328 3976-3981 NN denotes start
T1329 3982-3987 NN denotes sites
T1330 3988-3989 -LRB- denotes (
T1331 3989-3992 NN denotes TSS
T1332 3992-3993 -RRB- denotes )
T1333 3995-3997 IN denotes By
T1334 3998-4008 VB denotes generating
T1335 4009-4010 DT denotes a
T1336 4011-4017 NN denotes series
T1337 4018-4020 IN denotes of
T1338 4021-4023 CD denotes 5′
T1339 4024-4033 NN denotes deletions
T1340 4034-4036 IN denotes of
T1341 4037-4040 DT denotes the
T1342 4041-4044 NN denotes A3G
T1343 4045-4053 NN denotes promoter
T1344 4053-4054 -COMMA- denotes ,
T1345 4055-4057 PRP denotes we
T1346 4058-4068 VB denotes identified
T1347 4069-4070 DT denotes a
T1348 4071-4077 NN denotes 180 bp
T1349 4078-4084 NN denotes region
T1350 4085-4089 IN denotes that
T1351 4090-4098 VB denotes mediated
T1352 4099-4104 JJ denotes basal
T1353 4105-4118 NN denotes transcription
T1354 4120-4122 IN denotes In
T1355 4123-4124 NN denotes T
T1356 4125-4130 NN denotes cells
T1357 4130-4131 -COMMA- denotes ,
T1358 4132-4147 JJ denotes transcriptional
T1359 4148-4156 NN denotes activity
T1360 4157-4159 IN denotes of
T1361 4160-4164 DT denotes this
T1362 4165-4169 NN denotes core
T1363 4170-4178 NN denotes promoter
T1364 4179-4182 VB denotes was
T1365 4183-4186 RB denotes not
T1366 4187-4196 JJ denotes inducible
T1367 4197-4199 IN denotes by
T1368 4200-4209 JJ denotes mitogenic
T1369 4210-4221 NN denotes stimulation
T1370 4222-4224 CC denotes or
T1371 4225-4235 NN denotes interferon
T1372 4236-4245 NN denotes treatment
T1373 4245-4246 -COMMA- denotes ,
T1374 4247-4250 CC denotes but
T1375 4251-4254 VB denotes was
T1376 4255-4264 JJ denotes dependent
T1377 4265-4267 IN denotes on
T1378 4268-4269 DT denotes a
T1379 4270-4276 NN denotes GC-box
T1380 4277-4282 WDT denotes which
T1381 4283-4286 VB denotes was
T1382 4287-4297 VB denotes recognized
T1383 4298-4300 IN denotes by
T1384 4301-4303 NN denotes Sp
T1385 4304-4305 -LRB- denotes (
T1386 4305-4316 NN denotes specificity
T1387 4317-4324 NN denotes protein
T1388 4324-4325 -RRB- denotes )
T1389 4326-4327 CD denotes 1
T1390 4328-4331 CC denotes and
T1391 4332-4335 NN denotes Sp3
T1392 4336-4349 NN denotes transcription
T1393 4350-4357 NN denotes factors
T2315 4383-4387 NN denotes Cell
T2316 4388-4395 NN denotes culture
T2317 4396-4399 DT denotes The
T2318 4400-4405 JJ denotes human
T2319 4406-4407 NN denotes T
T2320 4408-4412 NN denotes cell
T2321 4413-4418 NN denotes lines
T2322 4419-4424 NN denotes A3.01
T2323 4425-4428 CC denotes and
T2324 4429-4432 NN denotes PM1
T2325 4433-4434 -LRB- denotes (
T2326 4434-4439 NNP denotes NIBSC
T2327 4439-4440 -COMMA- denotes ,
T2328 4441-4443 NNP denotes UK
T2329 4443-4444 -RRB- denotes )
T2330 4445-4448 CC denotes and
T2331 4449-4452 DT denotes the
T2332 4453-4458 JJ denotes human
T2333 4459-4466 JJ denotes myeloid
T2334 4467-4471 NN denotes cell
T2335 4472-4476 NN denotes line
T2336 4477-4481 NN denotes U937
T2337 4482-4483 -LRB- denotes (
T2338 4483-4488 NNP denotes NIBSC
T2339 4488-4489 -COMMA- denotes ,
T2340 4490-4492 NNP denotes UK
T2341 4492-4493 -RRB- denotes )
T2342 4494-4498 VB denotes were
T2343 4499-4504 VB denotes grown
T2344 4505-4507 IN denotes in
T2345 4508-4516 JJ denotes complete
T2346 4517-4521 NN denotes RPMI
T2347 4522-4526 CD denotes 1640
T2348 4527-4533 NN denotes medium
T2349 4534-4546 VB denotes supplemented
T2350 4547-4551 IN denotes with
T2351 4552-4554 CD denotes 10
T2352 4554-4555 NN denotes %
T2353 4556-4561 JJ denotes fetal
T2354 4562-4568 JJ denotes bovine
T2355 4569-4574 NN denotes serum
T2356 4574-4575 -COMMA- denotes ,
T2357 4576-4580 NN denotes 2 mM
T2358 4581-4592 NN denotes l-glutamine
T2359 4593-4596 CC denotes and
T2360 4597-4605 NN denotes 100 U/ml
T2361 4606-4629 NN denotes penicillin–streptomycin
T2362 4631-4634 DT denotes The
T2363 4635-4640 JJ denotes human
T2364 4641-4648 JJ denotes hepatic
T2365 4649-4653 NN denotes cell
T2366 4654-4659 NN denotes lines
T2367 4660-4665 NN denotes HepG2
T2368 4666-4669 CC denotes and
T2369 4670-4674 NN denotes Huh7
T2370 4675-4676 -LRB- denotes (
T2371 4676-4682 RB denotes kindly
T2372 4683-4691 VB denotes provided
T2373 4692-4694 IN denotes by
T2374 4695-4697 NNP denotes Dr
T2375 4698-4704 NNP denotes Thomas
T2376 4705-4716 NNP denotes Pietschmann
T2377 4716-4717 -COMMA- denotes ,
T2378 4718-4728 NNP denotes Department
T2379 4729-4731 IN denotes of
T2380 4732-4741 NNP denotes Molecular
T2381 4742-4750 NNP denotes Virology
T2382 4750-4751 -COMMA- denotes ,
T2383 4752-4762 NNP denotes University
T2384 4763-4765 IN denotes of
T2385 4766-4776 NNP denotes Heidelberg
T2386 4776-4777 -RRB- denotes )
T2387 4778-4780 RB denotes as
T2388 4781-4785 RB denotes well
T2389 4786-4788 IN denotes as
T2390 4789-4793 NN denotes HeLa
T2391 4794-4799 NN denotes cells
T2392 4800-4804 VB denotes were
T2393 4805-4815 VB denotes maintained
T2394 4816-4818 IN denotes in
T2395 4819-4827 NNP denotes Dulbecco
T2396 4827-4829 POS denotes 's
T2397 4830-4834 JJ denotes high
T2398 4835-4842 NN denotes glucose
T2399 4843-4851 VB denotes modified
T2400 4852-4857 NNP denotes Eagle
T2401 4857-4859 POS denotes 's
T2402 4860-4866 NN denotes medium
T2403 4867-4868 -LRB- denotes (
T2404 4868-4872 NN denotes DMEM
T2405 4872-4873 -RRB- denotes )
T2406 4874-4886 VB denotes supplemented
T2407 4887-4891 IN denotes with
T2408 4892-4894 CD denotes 10
T2409 4894-4895 NN denotes %
T2410 4896-4901 JJ denotes fetal
T2411 4902-4908 JJ denotes bovine
T2412 4909-4914 NN denotes serum
T2413 4914-4915 -COMMA- denotes ,
T2414 4916-4920 NN denotes 2 mM
T2415 4921-4932 NN denotes l-glutamine
T2416 4933-4936 CC denotes and
T2417 4937-4945 NN denotes 100 U/ml
T2418 4946-4969 NN denotes penicillin–streptomycin
T2419 4971-4976 NN denotes Cells
T2420 4977-4982 NN denotes lines
T2421 4983-4987 VB denotes were
T2422 4988-4997 VB denotes incubated
T2423 4998-5000 IN denotes at
T2424 5001-5005 NN denotes 37°C
T2425 5006-5010 IN denotes with
T2426 5011-5014 CD denotes 100
T2427 5014-5015 NN denotes %
T2428 5016-5024 NN denotes humidity
T2429 5025-5027 IN denotes in
T2430 5028-5031 CD denotes 5–7
T2431 5031-5032 NN denotes %
T2432 5033-5036 NN denotes CO2
T2433 5037-5040 CC denotes and
T2434 5041-5049 VB denotes passaged
T2435 5050-5055 VB denotes using
T2436 5056-5064 JJ denotes standard
T2437 5065-5069 NN denotes cell
T2438 5070-5077 NN denotes culture
T2439 5078-5088 NN denotes techniques
T3870 10494-10502 JJ denotes 5′-Rapid
T3871 10503-10516 NN denotes amplification
T3872 10517-10519 IN denotes of
T3873 10520-10524 NN denotes cDNA
T3874 10525-10529 VB denotes ends
T3875 10530-10538 NN denotes analysis
T3876 10539-10540 -LRB- denotes (
T3877 10540-10544 NN denotes RACE
T3878 10544-10545 -RRB- denotes )
T3879 10546-10551 JJ denotes Total
T3880 10552-10555 NN denotes RNA
T3881 10556-10559 VB denotes was
T3882 10560-10568 VB denotes isolated
T3883 10569-10573 IN denotes from
T3884 10574-10581 NN denotes A3.01 T
T3885 10582-10587 NN denotes cells
T3886 10588-10593 VB denotes using
T3887 10594-10600 NN denotes RNeasy
T3888 10601-10605 NN denotes mini
T3889 10606-10609 NN denotes kit
T3890 10610-10611 -LRB- denotes (
T3891 10611-10617 NN denotes Qiagen
T3892 10617-10618 -RRB- denotes )
T3893 10620-10623 DT denotes The
T3894 10624-10639 JJ denotes transcriptional
T3895 10640-10645 NN denotes start
T3896 10646-10651 NN denotes sites
T3897 10652-10654 IN denotes of
T3898 10655-10658 NN denotes A3G
T3899 10659-10663 VB denotes were
T3900 10664-10674 VB denotes identified
T3901 10675-10680 VB denotes using
T3902 10681-10684 DT denotes the
T3903 10685-10690 NN denotes 5′/3′
T3904 10691-10695 NN denotes RACE
T3905 10696-10699 NN denotes Kit
T3906 10699-10700 -COMMA- denotes ,
T3907 10701-10704 NN denotes 2nd
T3908 10705-10715 NN denotes Generation
T3909 10716-10717 -LRB- denotes (
T3910 10717-10722 NNP denotes Roche
T3911 10722-10723 -RRB- denotes )
T3912 10724-10733 VB denotes according
T3913 10734-10736 TO denotes to
T3914 10737-10740 DT denotes the
T3915 10741-10753 NN denotes manufacturer
T3916 10753-10755 POS denotes 's
T3917 10756-10768 NN denotes instructions
T3918 10770-10773 DT denotes The
T3919 10774-10783 VB denotes following
T3920 10784-10791 NN denotes primers
T3921 10792-10796 VB denotes were
T3922 10797-10801 VB denotes used
T3923 10801-10802 -COLON- denotes :
T3924 10803-10814 NN denotes RACE-APO3G1
T3925 10815-10816 -LRB- denotes (
T3926 10816-10841 NN denotes 5′-TATCCCTTGTACACTTTGT-3′
T3927 10841-10842 -RRB- denotes )
T3928 10843-10846 IN denotes for
T3929 10847-10851 NN denotes cDNA
T3930 10852-10861 NN denotes synthesis
T3931 10861-10862 -COMMA- denotes ,
T3932 10863-10874 NN denotes RACE-APO3G2
T3933 10875-10876 -LRB- denotes (
T3934 10876-10900 NN denotes 5′-CATACTCCTGGTCACGAT-3′
T3935 10900-10901 -RRB- denotes )
T3936 10902-10905 IN denotes for
T3937 10906-10909 DT denotes the
T3938 10910-10915 JJ denotes first
T3939 10916-10919 NN denotes PCR
T3940 10920-10923 CC denotes and
T3941 10924-10938 NN denotes RACE-APO3Gnest
T3942 10939-10940 -LRB- denotes (
T3943 10940-10965 NN denotes 5′-GAATACACCTGGCCTCGAA-3′
T3944 10965-10966 -RRB- denotes )
T3945 10967-10970 IN denotes for
T3946 10971-10974 DT denotes the
T3947 10975-10981 JJ denotes nested
T3948 10982-10985 NN denotes PCR
T3949 10987-10995 NN denotes Reaction
T3950 10996-11004 NN denotes products
T3951 11005-11009 VB denotes were
T3952 11010-11018 VB denotes analyzed
T3953 11019-11021 IN denotes by
T3954 11022-11029 NN denotes agarose
T3955 11030-11033 NN denotes gel
T3956 11034-11049 NN denotes electrophoresis
T3957 11049-11050 -COMMA- denotes ,
T3958 11051-11059 VB denotes purified
T3959 11060-11065 VB denotes using
T3960 11066-11074 JJ denotes QIAquick
T3961 11075-11078 NN denotes gel
T3962 11079-11089 NN denotes extraction
T3963 11090-11093 NN denotes kit
T3964 11094-11095 -LRB- denotes (
T3965 11095-11101 NN denotes Qiagen
T3966 11101-11102 -RRB- denotes )
T3967 11102-11103 -COMMA- denotes ,
T3968 11104-11114 JJ denotes T/A-cloned
T3969 11115-11119 IN denotes into
T3970 11120-11126 NN denotes vector
T3971 11127-11136 NN denotes pCR4-TOPO
T3972 11137-11138 -LRB- denotes (
T3973 11138-11148 NN denotes Invitrogen
T3974 11148-11149 -RRB- denotes )
T3975 11150-11153 CC denotes and
T3976 11154-11163 VB denotes sequenced
T4177 11166-11176 NN denotes Luciferase
T4178 11177-11182 NN denotes assay
T4179 11183-11186 IN denotes For
T4180 11187-11196 JJ denotes transient
T4181 11197-11209 NN denotes transfection
T4182 11210-11212 IN denotes of
T4183 11213-11218 NN denotes A3.01
T4184 11219-11222 CC denotes and
T4185 11223-11227 NN denotes U937
T4186 11228-11233 NN denotes cells
T4187 11233-11234 -COMMA- denotes ,
T4188 11235-11242 NN denotes DMRIE-C
T4189 11243-11255 NN denotes transfection
T4190 11256-11263 NN denotes reagent
T4191 11264-11265 -LRB- denotes (
T4192 11265-11269 NNP denotes Life
T4193 11270-11282 NNP denotes Technologies
T4194 11282-11283 -RRB- denotes )
T4195 11284-11287 VB denotes was
T4196 11288-11292 VB denotes used
T4197 11293-11294 -LRB- denotes (
T4198 11294-11296 CD denotes 36
T4199 11296-11297 -RRB- denotes )
T4200 11299-11304 NN denotes Cells
T4201 11305-11309 VB denotes were
T4202 11310-11316 VB denotes seeded
T4203 11317-11319 IN denotes in
T4204 11320-11326 JJ denotes 6-well
T4205 11327-11333 NN denotes tissue
T4206 11334-11341 NN denotes culture
T4207 11342-11348 NN denotes plates
T4208 11349-11350 -LRB- denotes (
T4209 11350-11363 NN denotes 5 × 105 cells
T4210 11364-11367 IN denotes per
T4211 11368-11372 RB denotes well
T4212 11372-11373 -RRB- denotes )
T4213 11374-11376 IN denotes in
T4214 11377-11383 NN denotes 1.5 ml
T4215 11384-11392 NN denotes Opti-MEM
T4216 11393-11394 -LRB- denotes (
T4217 11394-11398 NNP denotes Life
T4218 11399-11411 NNP denotes Technologies
T4219 11411-11412 -RRB- denotes )
T4220 11413-11423 VB denotes containing
T4221 11424-11430 NN denotes 0.5 µg
T4222 11431-11438 NN denotes firefly
T4223 11439-11449 NN denotes luciferase
T4224 11450-11458 NN denotes reporter
T4225 11459-11466 NN denotes plasmid
T4226 11467-11470 CC denotes and
T4227 11471-11477 NN denotes 3.5 µl
T4228 11478-11486 NNP denotes DMRIE-C.
T4229 11487-11492 IN denotes After
T4230 11493-11498 NN denotes 4–5 h
T4231 11499-11501 IN denotes of
T4232 11502-11512 NN denotes incubation
T4233 11512-11513 -COMMA- denotes ,
T4234 11514-11520 NN denotes 1.5 ml
T4235 11521-11529 JJ denotes complete
T4236 11530-11534 NN denotes RPMI
T4237 11535-11541 NN denotes medium
T4238 11542-11546 VB denotes were
T4239 11547-11552 VB denotes added
T4240 11554-11559 NN denotes HepG2
T4241 11560-11563 CC denotes and
T4242 11564-11568 NN denotes Huh7
T4243 11569-11573 NN denotes cell
T4244 11574-11579 NN denotes lines
T4245 11580-11584 VB denotes were
T4246 11585-11596 VB denotes transfected
T4247 11597-11602 VB denotes using
T4248 11603-11616 NNP denotes LipofectAMINE
T4249 11617-11621 NN denotes Plus
T4250 11622-11624 IN denotes as
T4251 11625-11636 VB denotes recommended
T4252 11637-11639 IN denotes by
T4253 11640-11643 DT denotes the
T4254 11644-11656 NN denotes manufacturer
T4255 11657-11658 -LRB- denotes (
T4256 11658-11662 NNP denotes Life
T4257 11663-11675 NNP denotes Technologies
T4258 11675-11676 -RRB- denotes )
T4259 11678-11685 RB denotes Briefly
T4260 11685-11686 -COMMA- denotes ,
T4261 11687-11698 JJ denotes exponential
T4262 11699-11706 VB denotes growing
T4263 11707-11712 NN denotes cells
T4264 11713-11714 -LRB- denotes (
T4265 11714-11723 CD denotes 1.5 × 106
T4266 11723-11724 -RRB- denotes )
T4267 11725-11729 VB denotes were
T4268 11730-11741 VB denotes transfected
T4269 11742-11746 IN denotes with
T4270 11747-11751 NN denotes 5 µl
T4271 11752-11765 NNP denotes LipofectAMINE
T4272 11765-11766 -COMMA- denotes ,
T4273 11767-11771 NN denotes 6 µl
T4274 11772-11776 NNP denotes PLUS
T4275 11777-11784 NN denotes reagent
T4276 11785-11788 CC denotes and
T4277 11789-11792 DT denotes the
T4278 11793-11801 JJ denotes required
T4279 11802-11808 NN denotes amount
T4280 11809-11811 IN denotes of
T4281 11812-11819 NN denotes plasmid
T4282 11820-11823 NN denotes DNA
T4283 11824-11826 IN denotes in
T4284 11827-11828 DT denotes a
T4285 11829-11834 JJ denotes final
T4286 11835-11841 NN denotes volume
T4287 11842-11844 IN denotes of
T4288 11845-11849 NN denotes 1 ml
T4289 11850-11858 NN denotes Opti-MEM
T4290 11860-11869 VB denotes Following
T4291 11870-11873 NN denotes 4 h
T4292 11874-11876 IN denotes of
T4293 11877-11887 NN denotes incubation
T4294 11887-11888 -COMMA- denotes ,
T4295 11889-11894 NN denotes cells
T4296 11895-11899 VB denotes were
T4297 11900-11906 VB denotes washed
T4298 11907-11909 IN denotes in
T4299 11910-11913 NNP denotes PBS
T4300 11914-11917 CC denotes and
T4301 11918-11922 NN denotes 3 ml
T4302 11923-11925 IN denotes of
T4303 11926-11934 JJ denotes complete
T4304 11935-11939 NN denotes DMEM
T4305 11940-11946 NN denotes medium
T4306 11947-11951 VB denotes were
T4307 11952-11957 VB denotes added
T4308 11959-11962 IN denotes For
T4309 11963-11977 NN denotes cotransfection
T4310 11978-11980 IN denotes of
T4311 11981-11989 NN denotes reporter
T4312 11990-11998 NN denotes plasmids
T4313 11999-12002 CC denotes and
T4314 12003-12008 NN denotes siRNA
T4315 12009-12013 IN denotes into
T4316 12014-12018 NN denotes HeLa
T4317 12019-12024 NN denotes cells
T4318 12024-12025 -COMMA- denotes ,
T4319 12026-12035 JJ denotes HiPerfect
T4320 12036-12048 NN denotes transfection
T4321 12049-12056 NN denotes reagent
T4322 12057-12058 -LRB- denotes (
T4323 12058-12064 NN denotes Qiagen
T4324 12064-12065 -RRB- denotes )
T4325 12066-12069 VB denotes was
T4326 12070-12074 VB denotes used
T4327 12075-12084 VB denotes according
T4328 12085-12087 TO denotes to
T4329 12088-12091 DT denotes the
T4330 12092-12104 NN denotes manufacturer
T4331 12104-12106 POS denotes 's
T4332 12107-12115 NN denotes protocol
T4333 12116-12119 IN denotes for
T4334 12120-12134 NN denotes cotransfection
T4335 12135-12137 IN denotes of
T4336 12138-12146 JJ denotes adherent
T4337 12147-12152 NN denotes cells
T4338 12153-12157 IN denotes with
T4339 12158-12163 NN denotes siRNA
T4340 12164-12167 CC denotes and
T4341 12168-12175 NN denotes plasmid
T4342 12176-12179 NN denotes DNA
T4343 12181-12184 CD denotes Two
T4344 12185-12189 NN denotes days
T4345 12190-12195 IN denotes after
T4346 12196-12208 NN denotes transfection
T4347 12209-12211 IN denotes of
T4348 12212-12215 DT denotes the
T4349 12216-12226 JJ denotes respective
T4350 12227-12231 NN denotes cell
T4351 12232-12237 NN denotes lines
T4352 12237-12238 -COMMA- denotes ,
T4353 12239-12244 NN denotes cells
T4354 12245-12249 VB denotes were
T4355 12250-12259 VB denotes harvested
T4356 12260-12262 IN denotes in
T4357 12263-12269 NN denotes 100 µl
T4358 12270-12271 -LRB- denotes (
T4359 12271-12281 NN denotes suspension
T4360 12282-12287 NN denotes cells
T4361 12287-12288 -RRB- denotes )
T4362 12289-12291 CC denotes or
T4363 12292-12298 CD denotes 300 µl
T4364 12299-12300 -LRB- denotes (
T4365 12300-12308 JJ denotes adherent
T4366 12309-12314 NN denotes cells
T4367 12314-12315 -RRB- denotes )
T4368 12316-12318 IN denotes of
T4369 12319-12326 JJ denotes Passive
T4370 12327-12332 NN denotes Lysis
T4371 12333-12339 NNP denotes Buffer
T4372 12340-12341 -LRB- denotes (
T4373 12341-12348 NNP denotes Promega
T4374 12348-12349 -RRB- denotes )
T4375 12350-12353 CC denotes and
T4376 12354-12364 NN denotes luciferase
T4377 12365-12370 NN denotes assay
T4378 12371-12374 VB denotes was
T4379 12375-12384 VB denotes performed
T4380 12385-12390 VB denotes using
T4381 12391-12394 DT denotes the
T4382 12395-12399 NNP denotes Dual
T4383 12400-12410 NNP denotes Luciferase
T4384 12411-12416 NNP denotes Assay
T4385 12417-12423 NNP denotes System
T4386 12424-12425 -LRB- denotes (
T4387 12425-12432 NNP denotes Promega
T4388 12432-12433 -RRB- denotes )
T4389 12434-12443 VB denotes according
T4390 12444-12446 TO denotes to
T4391 12447-12450 DT denotes the
T4392 12451-12463 NN denotes manufacturer
T4393 12463-12465 POS denotes 's
T4394 12466-12478 NN denotes instructions
T4395 12480-12482 IN denotes As
T4396 12483-12485 DT denotes an
T4397 12486-12494 JJ denotes internal
T4398 12495-12502 NN denotes control
T4399 12502-12503 -COMMA- denotes ,
T4400 12504-12509 CD denotes 50 ng
T4401 12510-12511 -LRB- denotes (
T4402 12511-12519 JJ denotes adherent
T4403 12520-12525 NN denotes cells
T4404 12525-12526 -RRB- denotes )
T4405 12527-12529 CC denotes or
T4406 12530-12536 NN denotes 100 ng
T4407 12537-12538 -LRB- denotes (
T4408 12538-12548 NN denotes suspension
T4409 12549-12554 NN denotes cells
T4410 12554-12555 -RRB- denotes )
T4411 12556-12558 IN denotes of
T4412 12559-12567 NN denotes ph-RG-TK
T4413 12568-12575 NN denotes plasmid
T4414 12576-12577 -LRB- denotes (
T4415 12577-12584 NN denotes Promega
T4416 12584-12585 -RRB- denotes )
T4417 12585-12586 -COMMA- denotes ,
T4418 12587-12592 WDT denotes which
T4419 12593-12607 RB denotes constitutively
T4420 12608-12617 VB denotes expresses
T4421 12618-12625 NN denotes renilla
T4422 12626-12636 NN denotes luciferase
T4423 12637-12640 VB denotes was
T4424 12641-12654 VB denotes cotransfected
T4425 12655-12657 IN denotes in
T4426 12658-12663 DT denotes every
T4427 12664-12670 NN denotes sample
T4428 12671-12674 CC denotes and
T4429 12675-12682 NN denotes firefly
T4430 12683-12693 NN denotes luciferase
T4431 12694-12704 NN denotes activities
T4432 12705-12709 VB denotes were
T4433 12710-12720 VB denotes normalized
T4434 12721-12723 TO denotes to
T4435 12724-12731 VB denotes renilla
T4436 12732-12742 NN denotes luciferase
T4437 12743-12753 NN denotes activities
T4438 12755-12759 NN denotes Mean
T4439 12760-12766 NN denotes values
T4440 12767-12768 -LRB- denotes (
T4441 12768-12771 NN denotes ±SD
T4442 12771-12772 -RRB- denotes )
T4443 12773-12775 IN denotes of
T4444 12776-12777 DT denotes a
T4445 12778-12792 JJ denotes representative
T4446 12793-12803 NN denotes experiment
T4447 12804-12813 VB denotes performed
T4448 12814-12816 IN denotes in
T4449 12817-12827 NN denotes triplicate
T4450 12828-12831 VB denotes are
T4451 12832-12837 VB denotes shown
T4452 12838-12840 IN denotes in
T4453 12841-12844 DT denotes the
T4454 12845-12852 NN denotes figures
T4455 12854-12857 IN denotes For
T4456 12858-12869 NN denotes stimulation
T4457 12870-12872 IN denotes of
T4458 12873-12878 NN denotes cells
T4459 12878-12879 -COMMA- denotes ,
T4460 12880-12885 JJ denotes final
T4461 12886-12900 NN denotes concentrations
T4462 12901-12903 IN denotes of
T4463 12904-12912 NN denotes 20 ng/ml
T4464 12913-12916 NN denotes TPA
T4465 12917-12918 -LRB- denotes (
T4466 12918-12923 NN denotes Sigma
T4467 12923-12924 -RRB- denotes )
T4468 12925-12927 CC denotes or
T4469 12928-12936 JJ denotes 30 ng/ml
T4470 12937-12942 NN denotes IFN-α
T4471 12943-12945 CC denotes or
T4472 12946-12954 CD denotes 30 ng/ml
T4473 12955-12960 NN denotes IFN-γ
T4474 12961-12962 -LRB- denotes (
T4475 12962-12970 NN denotes Tebu-Bio
T4476 12970-12971 -RRB- denotes )
T4477 12972-12976 VB denotes were
T4478 12977-12984 VB denotes applied
T4479 12985-12998 RB denotes approximately
T4480 12999-13003 RB denotes 15 h
T4481 13004-13010 IN denotes before
T4482 13011-13021 VB denotes harvesting
T4483 13022-13025 IN denotes for
T4484 13026-13036 NN denotes luciferase
T4485 13037-13042 NN denotes assay
T4986 13045-13060 JJ denotes Electrophoretic
T4987 13061-13069 NN denotes mobility
T4988 13070-13075 NN denotes shift
T4989 13076-13081 NN denotes assay
T4990 13082-13083 -LRB- denotes (
T4991 13083-13087 NN denotes EMSA
T4992 13087-13088 -RRB- denotes )
T4993 13089-13092 IN denotes For
T4994 13093-13104 NN denotes preparation
T4995 13105-13107 IN denotes of
T4996 13108-13115 JJ denotes nuclear
T4997 13116-13124 NN denotes extracts
T4998 13124-13125 -COMMA- denotes ,
T4999 13126-13133 CD denotes 5 × 106
T5000 13134-13141 NN denotes A3.01 T
T5001 13142-13147 NN denotes cells
T5002 13148-13152 VB denotes were
T5003 13153-13159 VB denotes washed
T5004 13160-13162 IN denotes in
T5005 13163-13167 JJ denotes cold
T5006 13168-13171 NN denotes PBS
T5007 13172-13175 CC denotes and
T5008 13176-13187 VB denotes resuspended
T5009 13188-13190 IN denotes in
T5010 13191-13197 CD denotes 500 µl
T5011 13198-13204 NN denotes buffer
T5012 13205-13206 NN denotes A
T5013 13207-13208 -LRB- denotes (
T5014 13208-13213 NN denotes 10 mM
T5015 13214-13219 NN denotes HEPES
T5016 13220-13225 NN denotes pH7.9
T5017 13225-13226 -COMMA- denotes ,
T5018 13227-13232 NN denotes 10 mM
T5019 13233-13236 NN denotes KCl
T5020 13236-13237 -COMMA- denotes ,
T5021 13238-13244 NNP denotes 0.1 mM
T5022 13245-13249 NNP denotes EDTA
T5023 13249-13250 -COMMA- denotes ,
T5024 13251-13257 NNP denotes 0.1 mM
T5025 13258-13262 NNP denotes EGTA
T5026 13262-13263 -COMMA- denotes ,
T5027 13264-13268 NN denotes 1 mM
T5028 13269-13272 NN denotes DTT
T5029 13272-13273 -COMMA- denotes ,
T5030 13274-13280 NN denotes 0.5 mM
T5031 13281-13285 NN denotes PMSF
T5032 13285-13286 -RRB- denotes )
T5033 13288-13293 IN denotes After
T5034 13294-13304 NN denotes incubation
T5035 13305-13308 IN denotes for
T5036 13309-13315 NN denotes 15 min
T5037 13316-13318 IN denotes on
T5038 13319-13322 NN denotes ice
T5039 13322-13323 -COMMA- denotes ,
T5040 13324-13331 NN denotes swollen
T5041 13332-13337 NN denotes cells
T5042 13338-13342 VB denotes were
T5043 13343-13350 VB denotes pressed
T5044 13351-13353 CD denotes 10
T5045 13354-13359 NN denotes times
T5046 13360-13367 IN denotes through
T5047 13368-13369 DT denotes a
T5048 13370-13377 NN denotes syringe
T5049 13378-13382 IN denotes with
T5050 13383-13384 DT denotes a
T5051 13385-13388 NN denotes 26G
T5052 13389-13395 NN denotes needle
T5053 13396-13399 CC denotes and
T5054 13400-13411 VB denotes centrifuged
T5055 13412-13414 IN denotes at
T5056 13415-13419 CD denotes 5000
T5057 13420-13426 NN denotes r.p.m.
T5058 13427-13430 IN denotes for
T5059 13431-13436 NN denotes 5 min
T5060 13438-13445 NN denotes Pellets
T5061 13446-13455 VB denotes contained
T5062 13456-13459 DT denotes the
T5063 13460-13466 NN denotes nuclei
T5064 13467-13470 CC denotes and
T5065 13471-13475 VB denotes were
T5066 13476-13482 VB denotes washed
T5067 13483-13485 IN denotes in
T5068 13486-13492 NN denotes buffer
T5069 13493-13494 NN denotes A
T5070 13495-13498 IN denotes for
T5071 13499-13502 CD denotes two
T5072 13503-13508 NN denotes times
T5073 13509-13512 CC denotes and
T5074 13513-13524 VB denotes resuspended
T5075 13525-13527 IN denotes in
T5076 13528-13533 CD denotes 50 µl
T5077 13534-13540 NN denotes buffer
T5078 13541-13542 NN denotes C
T5079 13543-13544 -LRB- denotes (
T5080 13544-13549 NN denotes 20 mM
T5081 13550-13555 NN denotes HEPES
T5082 13556-13558 NN denotes pH
T5083 13559-13562 CD denotes 7.9
T5084 13562-13563 -COMMA- denotes ,
T5085 13564-13570 NN denotes 400 mM
T5086 13571-13575 NN denotes NaCl
T5087 13575-13576 -COMMA- denotes ,
T5088 13577-13581 NN denotes 1 mM
T5089 13582-13586 NN denotes EDTA
T5090 13586-13587 -COMMA- denotes ,
T5091 13588-13592 NN denotes 1 mM
T5092 13593-13597 NN denotes EGTA
T5093 13598-13602 NN denotes 1 mM
T5094 13603-13606 NN denotes DTT
T5095 13606-13607 -COMMA- denotes ,
T5096 13608-13612 NN denotes 1 mM
T5097 13613-13617 NN denotes PMSF
T5098 13617-13618 -RRB- denotes )
T5099 13620-13625 IN denotes After
T5100 13626-13633 VB denotes shaking
T5101 13634-13637 IN denotes for
T5102 13638-13644 NN denotes 30 min
T5103 13645-13647 IN denotes at
T5104 13648-13651 NN denotes 4°C
T5105 13652-13655 CC denotes and
T5106 13656-13670 NN denotes centrifugation
T5107 13671-13674 IN denotes for
T5108 13675-13681 NN denotes 10 min
T5109 13682-13684 IN denotes at
T5110 13685-13687 CD denotes 13
T5111 13688-13691 CD denotes 000
T5112 13692-13698 NN denotes r.p.m.
T5113 13698-13699 -COMMA- denotes ,
T5114 13700-13712 NN denotes supernatants
T5115 13713-13717 VB denotes were
T5116 13718-13722 VB denotes used
T5117 13723-13725 IN denotes as
T5118 13726-13733 JJ denotes nuclear
T5119 13734-13742 NN denotes extracts
T5120 13744-13748 NN denotes EMSA
T5121 13749-13755 NN denotes probes
T5122 13756-13760 VB denotes were
T5123 13761-13770 VB denotes generated
T5124 13771-13773 IN denotes by
T5125 13774-13783 VB denotes annealing
T5126 13784-13787 DT denotes the
T5127 13788-13797 VB denotes following
T5128 13798-13811 JJ denotes complementary
T5129 13812-13828 NN denotes oligonucleotides
T5130 13828-13829 -COLON- denotes :
T5131 13830-13839 NN denotes APO-Sp1/3
T5132 13839-13840 -COMMA- denotes ,
T5133 13841-13844 JJ denotes 5′-
T5134 13845-13878 NN denotes CCAGCTGGGCGGGACCACCAGGGGAGGGGC-3′
T5135 13879-13882 CC denotes and
T5136 13883-13919 NN denotes 5′-GCCCCTCCCCTGGTGGTCCCGCCCAGCTGG-3′
T5137 13919-13920 -COLON- denotes ;
T5138 13921-13933 NN denotes APO-Sp1/3mut
T5139 13933-13934 -COMMA- denotes ,
T5140 13935-13938 JJ denotes 5′-
T5141 13939-13972 NN denotes CCAGCTGTTCGGGACCACCAGGGGAGGGGC-3′
T5142 13973-13976 CC denotes and
T5143 13977-13980 CD denotes 5′-
T5144 13981-14014 NN denotes GCCCCTCCCCTGGTGGTCCCGAACAGCTGG-3′
T5145 14015-14024 VB denotes according
T5146 14025-14027 TO denotes to
T5147 14028-14036 JJ denotes standard
T5148 14037-14047 NN denotes procedures
T5149 14049-14060 NN denotes Nucleotides
T5150 14061-14070 VB denotes differing
T5151 14071-14075 IN denotes from
T5152 14076-14079 DT denotes the
T5153 14080-14088 JJ denotes original
T5154 14089-14097 NN denotes promoter
T5155 14098-14106 NN denotes sequence
T5156 14107-14110 VB denotes are
T5157 14111-14116 VB denotes shown
T5158 14117-14119 IN denotes in
T5159 14120-14124 JJ denotes bold
T5160 14125-14129 NN denotes type
T5161 14131-14132 DT denotes A
T5162 14133-14145 RB denotes commercially
T5163 14146-14155 JJ denotes available
T5164 14156-14159 NN denotes Sp1
T5165 14160-14165 NN denotes probe
T5166 14166-14167 -LRB- denotes (
T5167 14167-14174 NN denotes sc-2502
T5168 14174-14175 -COMMA- denotes ,
T5169 14176-14184 VB denotes referred
T5170 14185-14187 TO denotes to
T5171 14188-14190 IN denotes as
T5172 14191-14198 NN denotes Sp1cons
T5173 14198-14199 -RRB- denotes )
T5174 14200-14203 VB denotes was
T5175 14204-14213 VB denotes purchased
T5176 14214-14218 IN denotes from
T5177 14219-14224 NNP denotes Santa
T5178 14225-14229 NNP denotes Cruz
T5179 14230-14244 NNP denotes Biotechnology.
T5180 14245-14248 DT denotes The
T5181 14249-14264 JJ denotes double-stranded
T5182 14265-14281 NN denotes oligonucleotides
T5183 14282-14286 VB denotes were
T5184 14287-14289 CD denotes 5′
T5185 14290-14301 VB denotes end-labeled
T5186 14302-14307 VB denotes using
T5187 14308-14310 NN denotes T4
T5188 14311-14325 NN denotes polynucleotide
T5189 14326-14332 NN denotes kinase
T5190 14333-14334 -LRB- denotes (
T5191 14334-14337 NNP denotes New
T5192 14338-14345 NNP denotes England
T5193 14346-14353 NNP denotes Biolabs
T5194 14353-14354 -RRB- denotes )
T5195 14355-14358 CC denotes and
T5196 14359-14360 -LRB- denotes [
T5197 14360-14365 NN denotes γ-32P
T5198 14365-14366 -RRB- denotes ]
T5199 14366-14369 NN denotes ATP
T5200 14370-14371 -LRB- denotes (
T5201 14371-14383 NN denotes 3000 Ci/mmol
T5202 14383-14384 -COMMA- denotes ,
T5203 14385-14393 NNP denotes Amersham
T5204 14393-14394 -RRB- denotes )
T5205 14395-14398 CC denotes and
T5206 14399-14407 VB denotes purified
T5207 14408-14410 IN denotes by
T5208 14411-14416 VB denotes using
T5209 14417-14421 NNP denotes Nick
T5210 14422-14425 NN denotes G50
T5211 14426-14433 NN denotes columns
T5212 14434-14435 -LRB- denotes (
T5213 14435-14443 NNP denotes Amersham
T5214 14443-14444 -RRB- denotes )
T5215 14446-14449 IN denotes For
T5216 14450-14454 NN denotes EMSA
T5217 14454-14455 -COMMA- denotes ,
T5218 14456-14460 NN denotes 5 µg
T5219 14461-14463 IN denotes of
T5220 14464-14471 JJ denotes nuclear
T5221 14472-14480 NN denotes proteins
T5222 14481-14485 VB denotes were
T5223 14486-14498 VB denotes preincubated
T5224 14499-14501 IN denotes on
T5225 14502-14505 NN denotes ice
T5226 14506-14510 IN denotes with
T5227 14511-14515 NN denotes 2 µg
T5228 14516-14518 IN denotes of
T5229 14519-14523 NN denotes poly
T5230 14523-14524 -LRB- denotes (
T5231 14524-14529 NN denotes dI-dC
T5232 14529-14530 -RRB- denotes )
T5233 14531-14532 -LRB- denotes (
T5234 14532-14537 NNP denotes Roche
T5235 14537-14538 -RRB- denotes )
T5236 14539-14541 IN denotes as
T5237 14542-14544 DT denotes an
T5238 14545-14555 JJ denotes unspecific
T5239 14556-14566 NN denotes competitor
T5240 14567-14570 CC denotes and
T5241 14571-14575 NN denotes 1 µg
T5242 14576-14578 IN denotes of
T5243 14579-14585 JJ denotes bovine
T5244 14586-14591 NN denotes serum
T5245 14592-14599 NN denotes albumin
T5246 14600-14602 IN denotes in
T5247 14603-14607 NN denotes band
T5248 14608-14613 NN denotes shift
T5249 14614-14620 NN denotes buffer
T5250 14621-14622 -LRB- denotes (
T5251 14622-14627 NNP denotes 50 mM
T5252 14628-14632 NNP denotes Tris
T5253 14632-14633 -COMMA- denotes ,
T5254 14634-14640 NN denotes 150 mM
T5255 14641-14644 NNP denotes KCl
T5256 14644-14645 -COMMA- denotes ,
T5257 14646-14650 NN denotes 5 mM
T5258 14651-14655 NN denotes EDTA
T5259 14655-14656 -COMMA- denotes ,
T5260 14657-14663 NN denotes 2.5 mM
T5261 14664-14678 NN denotes dithiothreitol
T5262 14678-14679 -COMMA- denotes ,
T5263 14680-14682 CD denotes 20
T5264 14682-14683 NN denotes %
T5265 14684-14690 NN denotes Ficoll
T5266 14690-14691 -RRB- denotes )
T5267 14692-14695 IN denotes for
T5268 14696-14702 NN denotes 15 min
T5269 14704-14715 JJ denotes 32P-labeled
T5270 14716-14732 NN denotes oligonucleotides
T5271 14733-14734 -LRB- denotes (
T5272 14734-14736 CD denotes 50
T5273 14737-14747 CD denotes 000 c.p.m.
T5274 14747-14748 -RRB- denotes )
T5275 14749-14753 VB denotes were
T5276 14754-14759 VB denotes added
T5277 14760-14762 IN denotes in
T5278 14763-14764 DT denotes a
T5279 14765-14770 JJ denotes total
T5280 14771-14777 NN denotes volume
T5281 14778-14780 IN denotes of
T5282 14781-14786 NN denotes 20 µl
T5283 14786-14787 -COMMA- denotes ,
T5284 14788-14797 VB denotes incubated
T5285 14798-14800 IN denotes on
T5286 14801-14804 NN denotes ice
T5287 14805-14808 IN denotes for
T5288 14809-14815 NN denotes 20 min
T5289 14816-14819 CC denotes and
T5290 14820-14826 VB denotes loaded
T5291 14827-14831 IN denotes onto
T5292 14832-14833 CD denotes 5
T5293 14833-14834 NN denotes %
T5294 14835-14841 JJ denotes native
T5295 14842-14856 NN denotes polyacrylamide
T5296 14857-14861 NN denotes gels
T5297 14862-14864 IN denotes in
T5298 14865-14885 NN denotes 0.5×Tris-borate-EDTA
T5299 14886-14892 NN denotes buffer
T5300 14894-14898 IN denotes Upon
T5301 14899-14912 NN denotes fractionation
T5302 14912-14913 -COMMA- denotes ,
T5303 14914-14918 NN denotes gels
T5304 14919-14923 VB denotes were
T5305 14924-14929 VB denotes dried
T5306 14930-14933 CC denotes and
T5307 14934-14941 VB denotes exposed
T5308 14942-14945 IN denotes for
T5309 14946-14961 NN denotes autoradiography
T5310 14963-14966 IN denotes For
T5311 14967-14978 NN denotes competition
T5312 14979-14990 NN denotes experiments
T5313 14990-14991 -COMMA- denotes ,
T5314 14992-14994 CD denotes 1-
T5315 14995-14997 CC denotes or
T5316 14998-15005 RB denotes 30-fold
T5317 15006-15011 JJ denotes molar
T5318 15012-15018 NN denotes excess
T5319 15019-15021 IN denotes of
T5320 15022-15025 DT denotes the
T5321 15026-15035 JJ denotes unlabeled
T5322 15036-15045 NN denotes APO-Sp1/3
T5323 15046-15048 CC denotes or
T5324 15049-15061 NN denotes APO-Sp1/3mut
T5325 15062-15078 NN denotes oligonucleotides
T5326 15079-15082 VB denotes was
T5327 15083-15088 VB denotes added
T5328 15089-15091 TO denotes to
T5329 15092-15095 DT denotes the
T5330 15096-15109 NN denotes preincubation
T5331 15110-15117 NN denotes mixture
T5332 15119-15122 IN denotes For
T5333 15123-15133 NN denotes supershift
T5334 15134-15145 NN denotes experiments
T5335 15145-15146 -COMMA- denotes ,
T5336 15147-15151 NN denotes 2 µg
T5337 15152-15155 NN denotes Sp1
T5338 15156-15164 NN denotes antibody
T5339 15165-15166 -LRB- denotes (
T5340 15166-15172 NN denotes sc-59x
T5341 15172-15173 -COMMA- denotes ,
T5342 15174-15179 NNP denotes Santa
T5343 15180-15184 NNP denotes Cruz
T5344 15185-15198 NNP denotes Biotechnology
T5345 15198-15199 -RRB- denotes )
T5346 15200-15202 CC denotes or
T5347 15203-15206 NN denotes Sp3
T5348 15207-15215 NN denotes antibody
T5349 15216-15217 -LRB- denotes (
T5350 15217-15224 NN denotes sc-644x
T5351 15224-15225 -COMMA- denotes ,
T5352 15226-15231 NNP denotes Santa
T5353 15232-15236 NNP denotes Cruz
T5354 15237-15250 NNP denotes Biotechnology
T5355 15250-15251 -RRB- denotes )
T5356 15252-15256 VB denotes were
T5357 15257-15262 VB denotes added
T5358 15263-15265 TO denotes to
T5359 15266-15269 DT denotes the
T5360 15270-15283 NN denotes preincubation
T5361 15284-15291 NN denotes mixture
T5362 15292-15295 CC denotes and
T5363 15296-15309 NN denotes preincubation
T5364 15310-15314 NN denotes time
T5365 15315-15318 VB denotes was
T5366 15319-15327 VB denotes extended
T5367 15328-15330 TO denotes to
T5368 15331-15337 VB denotes 30 min
T5974 15340-15349 NN denotes Chromatin
T5975 15350-15369 NN denotes immunoprecipitation
T5976 15370-15371 -LRB- denotes (
T5977 15371-15375 NN denotes ChIP
T5978 15375-15376 -RRB- denotes )
T5979 15377-15382 NN denotes assay
T5980 15383-15388 NN denotes A3.01
T5981 15389-15394 NN denotes cells
T5982 15395-15399 VB denotes were
T5983 15400-15407 VB denotes treated
T5984 15408-15412 IN denotes with
T5985 15413-15417 NN denotes RPMI
T5986 15418-15425 NN denotes culture
T5987 15426-15432 NN denotes medium
T5988 15433-15443 VB denotes containing
T5989 15444-15445 CD denotes 1
T5990 15445-15446 NN denotes %
T5991 15447-15459 NN denotes formaldehyde
T5992 15460-15463 IN denotes for
T5993 15464-15471 CD denotes 10 min.
T5994 15472-15474 IN denotes at
T5995 15475-15480 NNP denotes 37°C.
T5996 15481-15486 NNP denotes Cells
T5997 15487-15491 VB denotes were
T5998 15492-15498 VB denotes washed
T5999 15499-15504 RB denotes twice
T6000 15505-15509 IN denotes with
T6001 15510-15518 JJ denotes ice-cold
T6002 15519-15522 NN denotes PBS
T6003 15523-15526 CC denotes and
T6004 15527-15536 VB denotes incubated
T6005 15537-15540 IN denotes for
T6006 15541-15548 CD denotes 10 min.
T6007 15549-15551 IN denotes on
T6008 15552-15555 NN denotes ice
T6009 15556-15561 IN denotes after
T6010 15562-15574 NN denotes resuspension
T6011 15575-15577 IN denotes in
T6012 15578-15581 NN denotes SDS
T6013 15582-15587 NN denotes lysis
T6014 15588-15594 NN denotes buffer
T6015 15595-15596 -LRB- denotes (
T6016 15596-15600 NN denotes ChIP
T6017 15601-15606 NNP denotes Assay
T6018 15607-15610 NNP denotes Kit
T6019 15610-15611 -COMMA- denotes ,
T6020 15612-15619 NNP denotes Upstate
T6021 15619-15620 -RRB- denotes )
T6022 15622-15627 IN denotes After
T6023 15628-15642 NN denotes centrifugation
T6024 15642-15643 -COMMA- denotes ,
T6025 15644-15651 NN denotes pellets
T6026 15652-15656 VB denotes were
T6027 15657-15668 VB denotes resuspended
T6028 15669-15671 IN denotes in
T6029 15672-15677 NN denotes MNase
T6030 15678-15686 NN denotes reaction
T6031 15687-15693 NN denotes buffer
T6032 15694-15695 -LRB- denotes (
T6033 15695-15700 NN denotes 10 mM
T6034 15701-15709 NN denotes Tris-HCl
T6035 15710-15712 NN denotes pH
T6036 15713-15716 CD denotes 7.5
T6037 15716-15717 -COMMA- denotes ,
T6038 15718-15723 NN denotes 10 mM
T6039 15724-15728 NN denotes NaCl
T6040 15728-15729 -COMMA- denotes ,
T6041 15730-15734 NN denotes 3 mM
T6042 15735-15740 NN denotes MgCl2
T6043 15740-15741 -COMMA- denotes ,
T6044 15742-15746 NN denotes 1 mM
T6045 15747-15752 NN denotes CaCl2
T6046 15752-15753 -COMMA- denotes ,
T6047 15754-15755 CD denotes 4
T6048 15755-15756 NN denotes %
T6049 15757-15762 NN denotes NP-40
T6050 15762-15763 -RRB- denotes )
T6051 15765-15768 NN denotes DNA
T6052 15769-15778 NN denotes digestion
T6053 15779-15782 VB denotes was
T6054 15783-15792 VB denotes performed
T6055 15793-15798 VB denotes using
T6056 15799-15801 CD denotes 50
T6057 15802-15803 NNP denotes U
T6058 15804-15815 NNP denotes Micrococcal
T6059 15816-15824 NNP denotes Nuclease
T6060 15825-15826 -LRB- denotes (
T6061 15826-15835 NN denotes Fermentas
T6062 15835-15836 -RRB- denotes )
T6063 15837-15840 CC denotes and
T6064 15841-15848 CD denotes 1 × 107
T6065 15849-15854 NN denotes cells
T6066 15855-15858 IN denotes per
T6067 15859-15863 NN denotes tube
T6068 15864-15866 IN denotes in
T6069 15867-15868 DT denotes a
T6070 15869-15875 NN denotes volume
T6071 15876-15878 IN denotes of
T6072 15879-15885 NN denotes 1.5 ml
T6073 15887-15892 IN denotes After
T6074 15893-15898 NN denotes 2 min
T6075 15898-15899 -COMMA- denotes ,
T6076 15900-15908 NN denotes reaction
T6077 15909-15912 VB denotes was
T6078 15913-15920 VB denotes stopped
T6079 15921-15923 IN denotes by
T6080 15924-15930 VB denotes adding
T6081 15931-15936 JJ denotes 30 µl
T6082 15937-15943 NN denotes 200 mM
T6083 15944-15948 NN denotes EGTA
T6084 15950-15957 JJ denotes Further
T6085 15958-15963 NN denotes steps
T6086 15964-15968 VB denotes were
T6087 15969-15978 VB denotes performed
T6088 15979-15984 VB denotes using
T6089 15985-15988 DT denotes the
T6090 15989-15998 NNP denotes Chromatin
T6091 15999-16018 NNP denotes Immunoprecipitation
T6092 16019-16024 NNP denotes Assay
T6093 16025-16028 NN denotes Kit
T6094 16029-16030 -LRB- denotes (
T6095 16030-16037 NN denotes Upstate
T6096 16037-16038 -RRB- denotes )
T6097 16039-16048 VB denotes according
T6098 16049-16051 TO denotes to
T6099 16052-16055 DT denotes the
T6100 16056-16068 NN denotes manufacturer
T6101 16068-16070 POS denotes 's
T6102 16071-16083 NN denotes instructions
T6103 16085-16092 CD denotes 1 × 107
T6104 16093-16098 NN denotes cells
T6105 16099-16102 CC denotes and
T6106 16103-16107 NN denotes 2 µg
T6107 16108-16116 NN denotes antibody
T6108 16117-16118 -LRB- denotes (
T6109 16118-16121 NN denotes Sp1
T6110 16121-16122 -LRB- denotes (
T6111 16122-16126 NN denotes Pep2
T6112 16126-16127 -RRB- denotes )
T6113 16128-16133 NN denotes sc-59
T6114 16133-16134 -COMMA- denotes ,
T6115 16135-16138 NN denotes Sp3
T6116 16138-16139 -LRB- denotes (
T6117 16139-16143 NN denotes D-20
T6118 16143-16144 -RRB- denotes )
T6119 16145-16151 NN denotes sc-644
T6120 16152-16154 CC denotes or
T6121 16155-16160 NN denotes actin
T6122 16160-16161 -LRB- denotes (
T6123 16161-16166 NN denotes H-196
T6124 16166-16167 -RRB- denotes )
T6125 16168-16175 NN denotes sc-7210
T6126 16175-16176 -COMMA- denotes ,
T6127 16177-16182 NNP denotes Santa
T6128 16183-16187 NNP denotes Cruz
T6129 16188-16201 NNP denotes Biotechnology
T6130 16201-16202 -RRB- denotes )
T6131 16203-16207 VB denotes were
T6132 16208-16212 VB denotes used
T6133 16213-16216 IN denotes for
T6134 16217-16221 DT denotes each
T6135 16222-16241 NN denotes immunoprecipitation
T6136 16243-16246 DT denotes All
T6137 16247-16254 NN denotes buffers
T6138 16255-16259 VB denotes were
T6139 16260-16267 RB denotes freshly
T6140 16268-16276 VB denotes supplied
T6141 16277-16281 IN denotes with
T6142 16282-16290 NN denotes protease
T6143 16291-16301 NN denotes inhibitors
T6144 16303-16308 IN denotes After
T6145 16309-16326 NN denotes phenol/chloroform
T6146 16327-16337 NN denotes extraction
T6147 16338-16341 CC denotes and
T6148 16342-16349 NN denotes ethanol
T6149 16350-16363 NN denotes precipitation
T6150 16363-16364 -COMMA- denotes ,
T6151 16365-16368 NN denotes DNA
T6152 16369-16372 VB denotes was
T6153 16373-16381 VB denotes resolved
T6154 16382-16384 IN denotes in
T6155 16385-16390 NN denotes 16 µl
T6156 16391-16394 NN denotes H2O
T6157 16396-16414 VB denotes Immunoprecipitated
T6158 16415-16418 NN denotes DNA
T6159 16419-16422 VB denotes was
T6160 16423-16431 VB denotes detected
T6161 16432-16434 IN denotes by
T6162 16435-16441 VB denotes nested
T6163 16442-16445 NN denotes PCR
T6164 16446-16451 VB denotes using
T6165 16452-16456 NN denotes 4 µl
T6166 16457-16459 IN denotes of
T6167 16460-16463 DT denotes the
T6168 16464-16472 VB denotes resolved
T6169 16473-16476 NN denotes DNA
T6170 16477-16479 IN denotes in
T6171 16480-16483 DT denotes the
T6172 16484-16489 JJ denotes first
T6173 16490-16493 NN denotes PCR
T6174 16493-16494 -COMMA- denotes ,
T6175 16495-16498 CC denotes and
T6176 16499-16503 NN denotes 1 µl
T6177 16504-16507 IN denotes for
T6178 16508-16511 DT denotes the
T6179 16512-16518 JJ denotes nested
T6180 16519-16522 NN denotes PCR
T6181 16524-16527 IN denotes For
T6182 16528-16541 NN denotes amplification
T6183 16542-16544 IN denotes of
T6184 16545-16548 DT denotes the
T6185 16549-16552 NN denotes A3G
T6186 16553-16561 NN denotes promoter
T6187 16561-16562 -COMMA- denotes ,
T6188 16563-16566 DT denotes the
T6189 16567-16576 VB denotes following
T6190 16577-16584 NN denotes primers
T6191 16585-16589 VB denotes were
T6192 16590-16594 VB denotes used
T6193 16594-16595 -COLON- denotes :
T6194 16596-16606 NN denotes ChIP3Gplus
T6195 16607-16635 CD denotes 5′-ccacggtggcctccgagggtga-3′
T6196 16636-16639 CC denotes and
T6197 16640-16651 NN denotes ChIP3Gminus
T6198 16651-16652 -COLON- denotes :
T6199 16653-16680 CD denotes 5′-ctctccaccatcaagacagac-3′
T6200 16681-16682 -LRB- denotes (
T6201 16682-16683 CD denotes 1
T6202 16685-16688 NN denotes PCR
T6203 16688-16689 -RRB- denotes )
T6204 16689-16690 -COLON- denotes ;
T6205 16691-16702 NN denotes ChIP3G2plus
T6206 16702-16703 -COLON- denotes :
T6207 16704-16731 JJ denotes 5′-tactctccctccctgtcccca-3′
T6208 16732-16735 CC denotes and
T6209 16736-16742 NN denotes ChIP3G
T6210 16743-16749 VB denotes nested
T6211 16750-16755 NN denotes minus
T6212 16755-16756 -COLON- denotes :
T6213 16757-16781 CD denotes 5′-aggctgatgcctccgcag-3′
T6214 16782-16783 -LRB- denotes (
T6215 16783-16789 VB denotes nested
T6216 16790-16793 NN denotes PCR
T6217 16793-16794 -RRB- denotes )
T6218 16796-16799 NN denotes Taq
T6219 16800-16810 NN denotes polymerase
T6220 16811-16812 -LRB- denotes (
T6221 16812-16818 NN denotes Qiagen
T6222 16818-16819 -RRB- denotes )
T6223 16820-16823 VB denotes was
T6224 16824-16828 VB denotes used
T6225 16829-16837 RB denotes together
T6226 16838-16842 IN denotes with
T6227 16843-16846 DT denotes the
T6228 16847-16856 VB denotes following
T6229 16857-16862 NN denotes cycle
T6230 16863-16873 NN denotes conditions
T6231 16873-16874 -COLON- denotes :
T6232 16875-16878 CD denotes one
T6233 16879-16884 NN denotes cycle
T6234 16885-16889 NN denotes 94°C
T6235 16890-16893 IN denotes for
T6236 16894-16899 NN denotes 2 min
T6237 16899-16900 -COLON- denotes ;
T6238 16901-16903 CD denotes 30
T6239 16904-16910 NN denotes cycles
T6240 16911-16915 NN denotes 94°C
T6241 16916-16919 IN denotes for
T6242 16920-16924 NN denotes 30 s
T6243 16924-16925 -COMMA- denotes ,
T6244 16926-16930 NN denotes 60°C
T6245 16931-16934 IN denotes for
T6246 16935-16939 NN denotes 60 s
T6247 16939-16940 -COMMA- denotes ,
T6248 16941-16945 NN denotes 72°C
T6249 16946-16949 IN denotes for
T6250 16950-16955 NN denotes 2 min
T6251 16955-16956 -COLON- denotes ;
T6252 16957-16960 CD denotes one
T6253 16961-16966 NN denotes cycle
T6254 16967-16971 NN denotes 72°C
T6255 16972-16975 IN denotes for
T6256 16976-16982 NN denotes 10 min
T6257 16984-16986 IN denotes As
T6258 16987-16988 DT denotes a
T6259 16989-16997 JJ denotes negative
T6260 16998-17005 NN denotes control
T6261 17005-17006 -COMMA- denotes ,
T6262 17007-17008 DT denotes a
T6263 17009-17015 NN denotes region
T6264 17016-17018 IN denotes in
T6265 17019-17022 DT denotes the
T6266 17023-17026 NN denotes A3G
T6267 17027-17031 NN denotes gene
T6268 17032-17035 VB denotes was
T6269 17036-17044 VB denotes targeted
T6270 17045-17050 VB denotes using
T6271 17051-17054 DT denotes the
T6272 17055-17062 NN denotes primers
T6273 17063-17077 NN denotes ChIP3Gneg_plus
T6274 17077-17078 -COLON- denotes :
T6275 17079-17106 JJ denotes 5′-taagtaccacccagagatgag-3′
T6276 17107-17110 CC denotes and
T6277 17111-17126 NN denotes ChIP3Gneg_minus
T6278 17126-17127 -COLON- denotes :
T6279 17128-17155 NN denotes 5′-catgatcttcatggtggcacg-3′
T6280 17156-17159 IN denotes for
T6281 17160-17164 DT denotes both
T6282 17165-17168 NN denotes PCR
T6283 17169-17174 NN denotes steps
T6284 17176-17179 NN denotes PCR
T6285 17180-17190 NN denotes conditions
T6286 17191-17195 VB denotes were
T6287 17196-17199 DT denotes the
T6288 17200-17204 JJ denotes same
T6289 17205-17207 IN denotes as
T6290 17208-17211 IN denotes for
T6291 17212-17215 DT denotes the
T6292 17216-17219 NN denotes A3G
T6293 17220-17228 NN denotes promoter
T6294 17229-17237 NN denotes sequence
T6295 17237-17238 -COMMA- denotes ,
T6296 17239-17243 IN denotes with
T6297 17244-17247 DT denotes the
T6298 17248-17257 NN denotes exception
T6299 17258-17262 IN denotes that
T6300 17263-17272 VB denotes annealing
T6301 17273-17284 NN denotes temperature
T6302 17285-17288 VB denotes was
T6303 17289-17298 VB denotes decreased
T6304 17299-17301 TO denotes to
T6305 17302-17306 NN denotes 55°C
T6864 17309-17312 NN denotes RNA
T6865 17313-17325 NN denotes interference
T6866 17326-17329 CC denotes and
T6867 17330-17337 JJ denotes western
T6868 17338-17342 NN denotes blot
T6869 17343-17351 NN denotes analysis
T6870 17352-17355 NN denotes Sp1
T6871 17356-17359 CC denotes and
T6872 17360-17363 NN denotes Sp3
T6873 17364-17375 NN denotes translation
T6874 17376-17379 VB denotes was
T6875 17380-17388 VB denotes silenced
T6876 17389-17391 IN denotes in
T6877 17392-17396 NN denotes HeLa
T6878 17397-17402 NN denotes cells
T6879 17403-17408 VB denotes using
T6880 17409-17412 DT denotes the
T6881 17413-17418 NN denotes siRNA
T6882 17419-17427 NN denotes duplexes
T6883 17428-17439 NN denotes Hs_SP1_1_HP
T6884 17440-17443 CC denotes and
T6885 17444-17455 NN denotes Hs_SP3_1_HP
T6886 17456-17457 -LRB- denotes (
T6887 17457-17463 NN denotes Qiagen
T6888 17463-17464 -RRB- denotes )
T6889 17466-17467 DT denotes A
T6890 17468-17479 JJ denotes nonspecific
T6891 17480-17485 NN denotes siRNA
T6892 17486-17487 -LRB- denotes (
T6893 17487-17493 NN denotes Qiagen
T6894 17493-17494 -RRB- denotes )
T6895 17495-17498 VB denotes was
T6896 17499-17503 VB denotes used
T6897 17504-17506 IN denotes as
T6898 17507-17514 NN denotes control
T6899 17516-17520 NN denotes HeLa
T6900 17521-17526 NN denotes cells
T6901 17527-17531 VB denotes were
T6902 17532-17543 VB denotes transfected
T6903 17544-17548 IN denotes with
T6904 17549-17552 CD denotes 150
T6905 17553-17555 CC denotes or
T6906 17556-17562 CD denotes 300 ng
T6907 17563-17568 NN denotes siRNA
T6908 17569-17572 IN denotes per
T6909 17573-17579 NN denotes 6-well
T6910 17579-17580 -COMMA- denotes ,
T6911 17581-17586 VB denotes using
T6912 17587-17590 DT denotes the
T6913 17591-17600 JJ denotes HiPerfect
T6914 17601-17613 NN denotes transfection
T6915 17614-17621 NN denotes reagent
T6916 17622-17623 -LRB- denotes (
T6917 17623-17629 NN denotes Qiagen
T6918 17629-17630 -RRB- denotes )
T6919 17631-17640 VB denotes according
T6920 17641-17643 TO denotes to
T6921 17644-17647 DT denotes the
T6922 17648-17660 NN denotes manufacturer
T6923 17660-17662 POS denotes 's
T6924 17663-17671 NN denotes protocol
T6925 17672-17675 IN denotes for
T6926 17676-17683 JJ denotes reverse
T6927 17684-17696 NN denotes transfection
T6928 17697-17699 IN denotes of
T6929 17700-17708 JJ denotes adherent
T6930 17709-17714 NN denotes cells
T6931 17715-17717 IN denotes in
T6932 17718-17724 JJ denotes 6-well
T6933 17725-17731 NN denotes plates
T6934 17733-17744 CD denotes Forty-eight
T6935 17745-17750 NN denotes hours
T6936 17751-17756 IN denotes after
T6937 17757-17769 NN denotes transfection
T6938 17769-17770 -COMMA- denotes ,
T6939 17771-17775 NN denotes HeLa
T6940 17776-17781 NN denotes cells
T6941 17782-17786 VB denotes were
T6942 17787-17796 VB denotes harvested
T6943 17797-17800 IN denotes for
T6944 17801-17810 NN denotes detection
T6945 17811-17813 IN denotes of
T6946 17814-17817 NN denotes Sp1
T6947 17818-17821 CC denotes and
T6948 17822-17825 NN denotes Sp3
T6949 17826-17834 NN denotes proteins
T6950 17836-17841 NN denotes Cells
T6951 17842-17846 VB denotes were
T6952 17847-17853 VB denotes washed
T6953 17854-17856 IN denotes in
T6954 17857-17860 NNP denotes PBS
T6955 17860-17861 -COMMA- denotes ,
T6956 17862-17867 VB denotes lysed
T6957 17868-17870 IN denotes in
T6958 17871-17875 NN denotes RIPA
T6959 17876-17877 -LRB- denotes (
T6960 17877-17882 NN denotes 25 mM
T6961 17883-17887 NN denotes Tris
T6962 17888-17890 NN denotes pH
T6963 17891-17894 CD denotes 8.0
T6964 17894-17895 -COMMA- denotes ,
T6965 17896-17902 NN denotes 137 mM
T6966 17903-17907 NN denotes NaCl
T6967 17907-17908 -COMMA- denotes ,
T6968 17909-17910 CD denotes 1
T6969 17910-17911 NN denotes %
T6970 17912-17920 NN denotes Glycerol
T6971 17920-17921 -COMMA- denotes ,
T6972 17922-17925 CD denotes 0.5
T6973 17925-17926 NN denotes %
T6974 17927-17933 NN denotes sodium
T6975 17934-17946 NN denotes deoxycholate
T6976 17946-17947 -COMMA- denotes ,
T6977 17948-17949 CD denotes 1
T6978 17949-17950 NN denotes %
T6979 17951-17956 NN denotes NP-40
T6980 17956-17957 -COMMA- denotes ,
T6981 17958-17962 NN denotes 2 mM
T6982 17963-17967 NN denotes EDTA
T6983 17968-17970 NN denotes pH
T6984 17971-17972 CD denotes 8
T6985 17972-17973 -COMMA- denotes ,
T6986 17974-17977 CD denotes 0.1
T6987 17977-17978 NN denotes %
T6988 17979-17982 NN denotes SDS
T6989 17983-17986 CC denotes and
T6990 17987-17995 NN denotes protease
T6991 17996-18006 NN denotes inhibitors
T6992 18006-18007 -RRB- denotes )
T6993 18008-18011 CC denotes and
T6994 18012-18019 NN denotes lysates
T6995 18020-18024 VB denotes were
T6996 18025-18032 VB denotes cleared
T6997 18033-18035 IN denotes by
T6998 18036-18050 NN denotes centrifugation
T6999 18052-18057 IN denotes After
T7000 18058-18065 VB denotes boiling
T7001 18066-18070 IN denotes with
T7002 18071-18080 NN denotes Laemmli′s
T7003 18081-18087 NN denotes buffer
T7004 18087-18088 -COMMA- denotes ,
T7005 18089-18096 NN denotes samples
T7006 18097-18101 VB denotes were
T7007 18102-18111 VB denotes subjected
T7008 18112-18114 TO denotes to
T7009 18115-18133 NN denotes SDS–polyacrylamide
T7010 18134-18137 NN denotes gel
T7011 18138-18153 NN denotes electrophoresis
T7012 18154-18162 VB denotes followed
T7013 18163-18165 IN denotes by
T7014 18166-18174 NN denotes transfer
T7015 18175-18177 TO denotes to
T7016 18178-18179 DT denotes a
T7017 18180-18194 NN denotes nitrocellulose
T7018 18195-18203 NN denotes membrane
T7019 18205-18208 NN denotes Sp1
T7020 18209-18212 CC denotes and
T7021 18213-18216 NN denotes Sp3
T7022 18217-18225 NN denotes proteins
T7023 18226-18230 VB denotes were
T7024 18231-18239 VB denotes detected
T7025 18240-18245 VB denotes using
T7026 18246-18251 NN denotes α-Sp1
T7027 18251-18252 -LRB- denotes (
T7028 18252-18256 NN denotes Pep2
T7029 18256-18257 -RRB- denotes )
T7030 18258-18266 NN denotes antibody
T7031 18267-18268 -LRB- denotes (
T7032 18268-18273 NN denotes sc-59
T7033 18273-18274 -COMMA- denotes ,
T7034 18275-18280 NNP denotes Santa
T7035 18281-18285 NNP denotes Cruz
T7036 18285-18286 -RRB- denotes )
T7037 18287-18289 CC denotes or
T7038 18290-18295 NN denotes α-Sp3
T7039 18295-18296 -LRB- denotes (
T7040 18296-18300 NN denotes D-20
T7041 18300-18301 -RRB- denotes )
T7042 18302-18310 NN denotes antibody
T7043 18311-18312 -LRB- denotes (
T7044 18312-18318 NN denotes sc-644
T7045 18318-18319 -COMMA- denotes ,
T7046 18320-18325 NNP denotes Santa
T7047 18326-18330 NNP denotes Cruz
T7048 18330-18331 -RRB- denotes )
T7049 18332-18340 VB denotes followed
T7050 18341-18343 IN denotes by
T7051 18344-18354 NN denotes incubation
T7052 18355-18359 IN denotes with
T7053 18360-18372 NN denotes α-rabbit-HRP
T7054 18373-18374 -LRB- denotes (
T7055 18374-18382 NNP denotes Amersham
T7056 18383-18394 NNP denotes Biosciences
T7057 18394-18395 -RRB- denotes )
T7058 18397-18400 IN denotes For
T7059 18401-18410 NN denotes detection
T7060 18411-18413 IN denotes of
T7061 18414-18421 NN denotes tubulin
T7062 18421-18422 -COMMA- denotes ,
T7063 18423-18432 NN denotes α-tubulin
T7064 18433-18434 -LRB- denotes (
T7065 18434-18440 NN denotes B5-1-2
T7066 18440-18441 -COMMA- denotes ,
T7067 18442-18447 NNP denotes Sigma
T7068 18447-18448 -RRB- denotes )
T7069 18449-18452 CC denotes and
T7070 18453-18464 NN denotes α-mouse-HRP
T7071 18465-18466 -LRB- denotes (
T7072 18466-18474 NNP denotes Amersham
T7073 18475-18486 NNP denotes Biosciences
T7074 18486-18487 -RRB- denotes )
T7075 18488-18498 NN denotes antibodies
T7076 18499-18503 VB denotes were
T7077 18504-18508 VB denotes used
T7078 18510-18517 NN denotes Signals
T7079 18518-18522 VB denotes were
T7080 18523-18533 VB denotes visualized
T7081 18534-18536 IN denotes by
T7082 18537-18545 VB denotes enhanced
T7083 18546-18563 NN denotes chemiluminescence
T7084 18564-18565 -LRB- denotes (
T7085 18565-18568 NN denotes ECL
T7086 18568-18569 -COMMA- denotes ,
T7087 18570-18578 NNP denotes Amersham
T7088 18579-18590 NNP denotes Biosciences
T7089 18590-18591 -RRB- denotes )
T7499 18603-18619 NN denotes Characterization
T7500 18620-18622 IN denotes of
T7501 18623-18626 DT denotes the
T7502 18627-18642 JJ denotes transcriptional
T7503 18643-18648 NN denotes start
T7504 18649-18654 NN denotes sites
T7505 18655-18657 IN denotes of
T7506 18658-18666 NN denotes APOBEC3G
T7507 18667-18669 IN denotes by
T7508 18670-18677 NN denotes 5′-RACE
T7509 18678-18680 TO denotes To
T7510 18681-18689 VB denotes identify
T7511 18690-18693 DT denotes the
T7512 18694-18709 JJ denotes transcriptional
T7513 18710-18715 NN denotes start
T7514 18716-18721 NN denotes sites
T7515 18722-18723 -LRB- denotes (
T7516 18723-18726 NN denotes TSS
T7517 18726-18727 -RRB- denotes )
T7518 18728-18730 IN denotes of
T7519 18731-18739 NN denotes APOBEC3G
T7520 18740-18741 -LRB- denotes (
T7521 18741-18744 NN denotes A3G
T7522 18744-18745 -RRB- denotes )
T7523 18746-18748 IN denotes in
T7524 18749-18756 NN denotes A3.01 T
T7525 18757-18762 NN denotes cells
T7526 18762-18763 -COMMA- denotes ,
T7527 18764-18766 PRP denotes we
T7528 18767-18776 VB denotes performed
T7529 18777-18785 JJ denotes 5′-rapid
T7530 18786-18799 NN denotes amplification
T7531 18800-18802 IN denotes of
T7532 18803-18807 NN denotes cDNA
T7533 18808-18812 VB denotes ends
T7534 18813-18821 NN denotes analysis
T7535 18822-18823 -LRB- denotes (
T7536 18823-18827 NN denotes RACE
T7537 18827-18828 -RRB- denotes )
T7538 18829-18833 IN denotes with
T7539 18834-18846 JJ denotes A3G-specific
T7540 18847-18854 NN denotes primers
T7541 18855-18856 -LRB- denotes (
T7542 18856-18859 VB denotes see
T7543 18860-18866 NN denotes Figure
T7544 18867-18868 CD denotes 1
T7545 18868-18869 -RRB- denotes )
T7546 18871-18878 NN denotes Agarose
T7547 18879-18882 NN denotes gel
T7548 18883-18898 NN denotes electrophoresis
T7549 18899-18907 VB denotes resolved
T7550 18908-18911 DT denotes the
T7551 18912-18918 JJ denotes nested
T7552 18919-18922 NN denotes PCR
T7553 18923-18931 NN denotes products
T7554 18932-18936 IN denotes into
T7555 18937-18942 CD denotes three
T7556 18943-18948 NN denotes bands
T7557 18949-18951 IN denotes of
T7558 18952-18961 JJ denotes different
T7559 18962-18977 JJ denotes electrophoretic
T7560 18978-18986 NN denotes mobility
T7561 18987-18991 IN denotes with
T7562 18992-18993 DT denotes a
T7563 18994-19002 JJ denotes dominant
T7564 19003-19009 JJ denotes middle
T7565 19010-19014 NN denotes band
T7566 19015-19016 -LRB- denotes (
T7567 19016-19022 NN denotes Figure
T7568 19023-19024 CD denotes 2
T7569 19024-19025 -RRB- denotes )
T7570 19027-19030 IN denotes For
T7571 19031-19035 DT denotes each
T7572 19036-19040 NN denotes band
T7573 19040-19041 -COMMA- denotes ,
T7574 19042-19045 DT denotes the
T7575 19046-19049 NN denotes DNA
T7576 19050-19053 VB denotes was
T7577 19054-19060 VB denotes cloned
T7578 19061-19064 CC denotes and
T7579 19065-19073 NN denotes sequence
T7580 19074-19082 NN denotes analysis
T7581 19083-19085 IN denotes of
T7582 19086-19089 CD denotes six
T7583 19090-19092 CC denotes or
T7584 19093-19098 CD denotes seven
T7585 19099-19109 JJ denotes individual
T7586 19110-19123 NN denotes transformants
T7587 19124-19127 VB denotes was
T7588 19128-19137 VB denotes performed
T7589 19139-19141 PRP denotes We
T7590 19142-19150 VB denotes observed
T7591 19151-19155 IN denotes that
T7592 19156-19159 DT denotes the
T7593 19160-19175 JJ denotes transcriptional
T7594 19176-19181 NN denotes start
T7595 19182-19187 NN denotes sites
T7596 19188-19190 IN denotes of
T7597 19191-19194 DT denotes the
T7598 19195-19198 NN denotes A3G
T7599 19199-19203 NN denotes gene
T7600 19204-19208 VB denotes were
T7601 19209-19216 JJ denotes located
T7602 19217-19224 IN denotes between
T7603 19225-19227 CD denotes 58
T7604 19228-19231 CC denotes and
T7605 19232-19238 NN denotes 361 nt
T7606 19239-19247 RB denotes upstream
T7607 19248-19250 IN denotes of
T7608 19251-19254 DT denotes the
T7609 19255-19258 NN denotes ATG
T7610 19259-19264 NN denotes start
T7611 19265-19270 NN denotes codon
T7612 19271-19272 -LRB- denotes (
T7613 19272-19278 NN denotes Figure
T7614 19279-19280 CD denotes 1
T7615 19280-19281 -RRB- denotes )
T7616 19283-19291 IN denotes Although
T7617 19292-19295 NN denotes TSS
T7618 19296-19300 VB denotes were
T7619 19301-19309 JJ denotes variable
T7620 19310-19313 CC denotes and
T7621 19314-19318 JJ denotes most
T7622 19319-19324 NN denotes sites
T7623 19325-19329 VB denotes were
T7624 19330-19334 RB denotes only
T7625 19335-19343 VB denotes detected
T7626 19344-19348 RB denotes once
T7627 19349-19354 IN denotes among
T7628 19355-19358 DT denotes the
T7629 19359-19361 CD denotes 19
T7630 19362-19368 NN denotes clones
T7631 19369-19377 VB denotes analyzed
T7632 19377-19378 -COMMA- denotes ,
T7633 19379-19382 CD denotes one
T7634 19383-19386 NN denotes TSS
T7635 19387-19390 VB denotes was
T7636 19391-19401 VB denotes identified
T7637 19402-19404 IN denotes in
T7638 19405-19408 CD denotes six
T7639 19409-19419 JJ denotes individual
T7640 19420-19426 NN denotes clones
T7641 19428-19432 DT denotes This
T7642 19433-19436 NN denotes TSS
T7643 19437-19440 VB denotes was
T7644 19441-19448 VB denotes located
T7645 19449-19454 RB denotes 66 nt
T7646 19455-19463 RB denotes upstream
T7647 19464-19466 IN denotes of
T7648 19467-19470 DT denotes the
T7649 19471-19476 NN denotes start
T7650 19477-19479 IN denotes of
T7651 19480-19483 DT denotes the
T7652 19484-19493 VB denotes published
T7653 19494-19497 NN denotes A3G
T7654 19498-19502 NN denotes mRNA
T7655 19503-19511 NN denotes sequence
T7656 19512-19513 -LRB- denotes (
T7657 19513-19521 NN denotes GenBank™
T7658 19522-19531 NN denotes accession
T7659 19532-19538 NN denotes number
T7660 19539-19547 NN denotes NM021822
T7661 19547-19548 -RRB- denotes )
T7662 19549-19552 CC denotes and
T7663 19553-19555 PRP denotes we
T7664 19556-19563 VB denotes defined
T7665 19564-19568 DT denotes this
T7666 19569-19577 NN denotes position
T7667 19578-19580 IN denotes as
T7668 19581-19584 DT denotes the
T7669 19585-19590 JJ denotes major
T7670 19591-19606 JJ denotes transcriptional
T7671 19607-19612 NN denotes start
T7672 19613-19617 NN denotes site
T7673 19618-19620 IN denotes of
T7674 19621-19624 DT denotes the
T7675 19625-19628 NN denotes A3G
T7676 19629-19633 NN denotes gene
T18365 19645-19653 NN denotes Sequence
T18366 19654-19656 IN denotes of
T18367 19657-19660 DT denotes the
T18368 19661-19664 NN denotes A3G
T18369 19665-19673 NN denotes promoter
T18370 19674-19677 CC denotes and
T18371 19678-19681 DT denotes the
T18372 19682-19692 JJ denotes downstream
T18373 19693-19699 NN denotes region
T18374 19701-19704 DT denotes The
T18375 19705-19710 JJ denotes first
T18376 19711-19718 NN denotes 1000 bp
T18377 19719-19727 RB denotes upstream
T18378 19728-19730 IN denotes of
T18379 19731-19734 DT denotes the
T18380 19735-19740 JJ denotes major
T18381 19741-19744 NN denotes TSS
T18382 19745-19748 VB denotes are
T18383 19749-19754 VB denotes shown
T18384 19755-19757 IN denotes in
T18385 19758-19763 JJ denotes lower
T18386 19764-19768 NN denotes case
T18387 19768-19769 -COMMA- denotes ,
T18388 19770-19773 DT denotes the
T18389 19774-19779 JJ denotes first
T18390 19780-19786 NN denotes 800 bp
T18391 19787-19789 IN denotes of
T18392 19790-19793 DT denotes the
T18393 19794-19805 VB denotes transcribed
T18394 19806-19814 NN denotes sequence
T18395 19815-19818 VB denotes are
T18396 19819-19824 VB denotes shown
T18397 19825-19827 IN denotes in
T18398 19828-19833 JJ denotes upper
T18399 19834-19838 NN denotes case
T18400 19840-19847 NN denotes Introns
T18401 19848-19851 VB denotes are
T18402 19852-19859 VB denotes removed
T18403 19859-19860 -COMMA- denotes ,
T18404 19861-19864 CC denotes but
T18405 19865-19870 PRP-DOLLAR- denotes their
T18406 19871-19880 NN denotes positions
T18407 19881-19884 VB denotes are
T18408 19885-19894 VB denotes indicated
T18409 19896-19902 NN denotes Arrows
T18410 19903-19908 VB denotes refer
T18411 19909-19911 TO denotes to
T18412 19912-19927 JJ denotes transcriptional
T18413 19928-19933 NN denotes start
T18414 19934-19939 NN denotes sites
T18415 19940-19943 CC denotes and
T18416 19944-19949 PRP-DOLLAR- denotes their
T18417 19950-19958 VB denotes observed
T18418 19959-19968 NN denotes frequency
T18419 19969-19971 VB denotes is
T18420 19972-19977 VB denotes given
T18421 19978-19980 IN denotes by
T18422 19981-19984 DT denotes the
T18423 19985-19992 NN denotes numbers
T18424 19993-19998 RB denotes above
T18425 20000-20003 DT denotes The
T18426 20004-20010 NN denotes primer
T18427 20011-20018 NN denotes binding
T18428 20019-20024 NN denotes sites
T18429 20025-20028 IN denotes for
T18430 20029-20036 NN denotes 5′-RACE
T18431 20037-20045 NN denotes analysis
T18432 20046-20049 CC denotes and
T18433 20050-20057 NN denotes cloning
T18434 20058-20060 IN denotes of
T18435 20061-20064 DT denotes the
T18436 20065-20075 NN denotes luciferase
T18437 20076-20084 NN denotes reporter
T18438 20085-20095 NN denotes constructs
T18439 20096-20099 VB denotes are
T18440 20100-20110 VB denotes underlined
T18441 20111-20114 CC denotes and
T18442 20115-20118 DT denotes the
T18443 20119-20124 NN denotes names
T18444 20125-20127 IN denotes of
T18445 20128-20131 DT denotes the
T18446 20132-20139 NN denotes primers
T18447 20140-20143 VB denotes are
T18448 20144-20153 VB denotes annotated
T18449 20155-20159 NNP denotes Gray
T18450 20160-20163 CC denotes and
T18451 20164-20169 JJ denotes black
T18452 20170-20180 NN denotes arrowheads
T18453 20181-20187 VB denotes define
T18454 20188-20191 DT denotes the
T18455 20192-20199 NN denotes regions
T18456 20200-20210 VB denotes designated
T18457 20211-20213 NN denotes E1
T18458 20214-20217 CC denotes and
T18459 20218-20220 NN denotes E2
T18460 20221-20226 WDT denotes which
T18461 20227-20231 VB denotes were
T18462 20232-20238 VB denotes cloned
T18463 20239-20243 IN denotes into
T18464 20244-20250 NN denotes vector
T18465 20251-20264 NN denotes pGL3-Promoter
T18466 20265-20268 CC denotes and
T18467 20269-20273 VB denotes used
T18468 20274-20276 IN denotes as
T18469 20277-20281 NN denotes EMSA
T18470 20282-20288 NN denotes probes
T18471 20290-20293 DT denotes The
T18472 20294-20297 NN denotes ATG
T18473 20298-20303 NN denotes start
T18474 20304-20309 NN denotes codon
T18475 20310-20313 CC denotes and
T18476 20314-20317 DT denotes the
T18477 20318-20328 VB denotes identified
T18478 20329-20336 NN denotes Sp1/Sp3
T18479 20337-20350 NN denotes transcription
T18480 20351-20357 NN denotes factor
T18481 20358-20365 NN denotes binding
T18482 20366-20370 NN denotes site
T18483 20371-20374 VB denotes are
T18484 20375-20380 VB denotes shown
T18485 20381-20383 IN denotes in
T18486 20384-20388 NN denotes bold
T18678 20400-20407 NN denotes 5′-RACE
T18679 20408-20416 NN denotes analysis
T18680 20417-20419 IN denotes of
T18681 20420-20423 DT denotes the
T18682 20424-20427 NN denotes A3G
T18683 20428-20432 NN denotes cDNA
T18684 20434-20441 NN denotes Agarose
T18685 20442-20445 NN denotes gel
T18686 20446-20461 NN denotes electrophoresis
T18687 20462-20464 IN denotes of
T18688 20465-20469 NN denotes size
T18689 20470-20476 NN denotes marker
T18690 20477-20480 CC denotes and
T18691 20481-20484 NN denotes A3G
T18692 20485-20492 NN denotes 5′-RACE
T18693 20493-20501 NN denotes products
T18694 20502-20507 IN denotes after
T18695 20508-20514 JJ denotes nested
T18696 20515-20518 NN denotes PCR
T18697 20519-20523 IN denotes with
T18698 20524-20530 NN denotes primer
T18699 20531-20545 NN denotes RACE-APO3Gnest
T18700 20546-20547 -LRB- denotes (
T18701 20547-20550 VB denotes see
T18702 20551-20557 NNP denotes Figure
T18703 20558-20559 CD denotes 1
T18704 20560-20563 IN denotes for
T18705 20564-20570 NN denotes primer
T18706 20571-20578 NN denotes details
T18707 20578-20579 -RRB- denotes )
T18708 20581-20591 NN denotes Arrowheads
T18709 20592-20600 VB denotes indicate
T18710 20601-20604 DT denotes the
T18711 20605-20610 CD denotes three
T18712 20611-20620 VB denotes resulting
T18713 20621-20624 NN denotes DNA
T18714 20625-20630 NN denotes bands
T18715 20631-20636 WDT denotes which
T18716 20637-20641 VB denotes were
T18717 20642-20648 VB denotes cloned
T18718 20649-20652 CC denotes and
T18719 20653-20662 VB denotes sequenced
T7993 20665-20668 DT denotes The
T7994 20669-20673 NN denotes core
T7995 20674-20682 NN denotes promoter
T7996 20683-20685 IN denotes of
T7997 20686-20689 NN denotes A3G
T7998 20690-20692 VB denotes is
T7999 20693-20700 JJ denotes located
T8000 20701-20707 IN denotes within
T8001 20708-20711 DT denotes the
T8002 20712-20718 NN denotes region
T8003 20719-20727 CD denotes −114/+66
T8004 20728-20736 JJ denotes relative
T8005 20737-20739 TO denotes to
T8006 20740-20743 DT denotes the
T8007 20744-20747 NN denotes TSS
T8008 20748-20751 IN denotes For
T8009 20752-20768 NN denotes characterization
T8010 20769-20771 IN denotes of
T8011 20772-20775 DT denotes the
T8012 20776-20779 NN denotes A3G
T8013 20780-20788 NN denotes promoter
T8014 20788-20789 -COMMA- denotes ,
T8015 20790-20792 PRP denotes we
T8016 20793-20799 VB denotes cloned
T8017 20800-20803 DT denotes the
T8018 20804-20811 NN denotes 1025 bp
T8019 20812-20819 JJ denotes located
T8020 20820-20822 IN denotes at
T8021 20823-20831 NN denotes position
T8022 20832-20840 CD denotes −959/+66
T8023 20841-20849 JJ denotes relative
T8024 20850-20852 TO denotes to
T8025 20853-20856 DT denotes the
T8026 20857-20867 VB denotes identified
T8027 20868-20881 NN denotes transcription
T8028 20882-20887 NN denotes start
T8029 20888-20892 IN denotes into
T8030 20893-20896 DT denotes the
T8031 20897-20909 JJ denotes promoterless
T8032 20910-20920 JJ denotes pGL3-Basic
T8033 20921-20931 NN denotes luciferase
T8034 20932-20940 NN denotes reporter
T8035 20941-20948 NN denotes plasmid
T8036 20949-20952 CC denotes and
T8037 20953-20963 VB denotes designated
T8038 20964-20967 DT denotes the
T8039 20968-20975 NN denotes plasmid
T8040 20976-20998 NN denotes pGL3-Basic-APOprom1025
T8041 21000-21009 RB denotes Similarly
T8042 21009-21010 -COMMA- denotes ,
T8043 21011-21026 NN denotes pGL3-APOprom502
T8044 21027-21028 -LRB- denotes (
T8045 21028-21038 VB denotes containing
T8046 21039-21047 NN denotes sequence
T8047 21048-21056 CD denotes −436/+66
T8048 21056-21057 -RRB- denotes )
T8049 21057-21058 -COMMA- denotes ,
T8050 21059-21074 NN denotes pGL3-APOprom225
T8051 21075-21076 -LRB- denotes (
T8052 21076-21086 VB denotes containing
T8053 21087-21095 NN denotes sequence
T8054 21096-21104 CD denotes −159/+66
T8055 21104-21105 -RRB- denotes )
T8056 21106-21109 CC denotes and
T8057 21110-21117 RB denotes further
T8058 21118-21120 CD denotes 5′
T8059 21121-21129 NN denotes deletion
T8060 21130-21138 NN denotes reporter
T8061 21139-21149 NN denotes constructs
T8062 21150-21160 VB denotes containing
T8063 21161-21164 CD denotes 180
T8064 21164-21165 -COMMA- denotes ,
T8065 21166-21169 CD denotes 150
T8066 21169-21170 -COMMA- denotes ,
T8067 21171-21174 CD denotes 120
T8068 21175-21177 CC denotes or
T8069 21178-21183 NN denotes 60 bp
T8070 21184-21192 RB denotes upstream
T8071 21193-21195 IN denotes of
T8072 21196-21204 NN denotes position
T8073 21205-21208 CD denotes +65
T8074 21209-21213 VB denotes were
T8075 21214-21223 VB denotes generated
T8076 21224-21225 -LRB- denotes (
T8077 21225-21231 NN denotes Figure
T8078 21232-21234 NN denotes 3A
T8079 21234-21235 -RRB- denotes )
T8080 21237-21239 IN denotes In
T8081 21240-21245 NN denotes order
T8082 21246-21248 TO denotes to
T8083 21249-21256 VB denotes analyze
T8084 21257-21272 JJ denotes transcriptional
T8085 21273-21281 NN denotes activity
T8086 21281-21282 -COMMA- denotes ,
T8087 21283-21286 DT denotes the
T8088 21287-21297 NN denotes luciferase
T8089 21298-21306 NN denotes reporter
T8090 21307-21315 NN denotes plasmids
T8091 21316-21320 VB denotes were
T8092 21321-21332 RB denotes transiently
T8093 21333-21344 VB denotes transfected
T8094 21345-21349 IN denotes into
T8095 21350-21357 NN denotes A3.01 T
T8096 21358-21363 NN denotes cells
T8097 21365-21375 NN denotes Luciferase
T8098 21376-21382 NN denotes assays
T8099 21383-21391 VB denotes revealed
T8100 21392-21393 DT denotes a
T8101 21394-21402 RB denotes ∼20-fold
T8102 21403-21412 VB denotes increased
T8103 21413-21428 JJ denotes transcriptional
T8104 21429-21437 NN denotes activity
T8105 21438-21440 IN denotes of
T8106 21441-21444 DT denotes the
T8107 21445-21452 NN denotes 1025 bp
T8108 21453-21461 NN denotes sequence
T8109 21462-21464 IN denotes as
T8110 21465-21473 VB denotes compared
T8111 21474-21476 TO denotes to
T8112 21477-21480 DT denotes the
T8113 21481-21486 JJ denotes empty
T8114 21487-21493 NN denotes vector
T8115 21493-21494 -COMMA- denotes ,
T8116 21495-21505 VB denotes indicating
T8117 21506-21510 IN denotes that
T8118 21511-21513 PRP denotes we
T8119 21514-21517 VB denotes had
T8120 21518-21528 VB denotes identified
T8121 21529-21531 DT denotes an
T8122 21532-21538 JJ denotes active
T8123 21539-21542 NN denotes A3G
T8124 21543-21551 NN denotes promoter
T8125 21552-21560 NN denotes sequence
T8126 21561-21562 -LRB- denotes (
T8127 21562-21568 NN denotes Figure
T8128 21569-21571 NN denotes 3B
T8129 21571-21572 -RRB- denotes )
T8130 21574-21578 DT denotes This
T8131 21579-21592 NN denotes transcription
T8132 21593-21597 NN denotes rate
T8133 21598-21601 VB denotes was
T8134 21602-21605 RB denotes not
T8135 21606-21619 RB denotes significantly
T8136 21620-21627 VB denotes altered
T8137 21628-21630 IN denotes by
T8138 21631-21634 DT denotes the
T8139 21635-21637 NN denotes 5′
T8140 21638-21647 NN denotes deletions
T8141 21648-21655 VB denotes leading
T8142 21656-21658 TO denotes to
T8143 21659-21662 DT denotes the
T8144 21663-21666 CD denotes 502
T8145 21666-21667 -COMMA- denotes ,
T8146 21668-21671 CD denotes 225
T8147 21672-21675 CC denotes and
T8148 21676-21682 NN denotes 180 bp
T8149 21683-21692 NN denotes fragments
T8150 21693-21694 -LRB- denotes (
T8151 21694-21700 NN denotes Figure
T8152 21701-21703 NN denotes 3B
T8153 21703-21704 -RRB- denotes )
T8154 21706-21708 IN denotes In
T8155 21709-21717 NN denotes contrast
T8156 21717-21718 -COMMA- denotes ,
T8157 21719-21720 DT denotes a
T8158 21721-21725 NN denotes drop
T8159 21726-21728 IN denotes in
T8160 21729-21739 NN denotes luciferase
T8161 21740-21748 NN denotes activity
T8162 21749-21752 VB denotes was
T8163 21753-21761 VB denotes observed
T8164 21762-21764 IN denotes in
T8165 21765-21768 DT denotes the
T8166 21769-21773 NN denotes case
T8167 21774-21776 IN denotes of
T8168 21777-21780 DT denotes the
T8169 21781-21787 NN denotes 150 bp
T8170 21788-21796 NN denotes fragment
T8171 21798-21802 DT denotes This
T8172 21803-21812 NN denotes construct
T8173 21813-21817 RB denotes only
T8174 21818-21826 VB denotes retained
T8175 21827-21829 CD denotes 28
T8176 21829-21830 NN denotes %
T8177 21831-21833 IN denotes of
T8178 21834-21837 DT denotes the
T8179 21838-21853 JJ denotes transcriptional
T8180 21854-21862 NN denotes activity
T8181 21863-21865 IN denotes of
T8182 21866-21869 DT denotes the
T8183 21870-21876 NN denotes 180 bp
T8184 21877-21885 NN denotes promoter
T8185 21886-21888 IN denotes in
T8186 21889-21896 NN denotes A3.01 T
T8187 21897-21902 NN denotes cells
T8188 21903-21906 CC denotes and
T8189 21907-21915 NN denotes activity
T8190 21916-21918 IN denotes of
T8191 21919-21922 DT denotes the
T8192 21923-21929 NN denotes 120 bp
T8193 21930-21938 NN denotes fragment
T8194 21939-21942 VB denotes was
T8195 21943-21950 RB denotes further
T8196 21951-21958 VB denotes reduced
T8197 21960-21970 JJ denotes Comparable
T8198 21971-21981 NN denotes reductions
T8199 21982-21990 JJ denotes relative
T8200 21991-21993 TO denotes to
T8201 21994-21997 DT denotes the
T8202 21998-22006 NN denotes activity
T8203 22007-22009 IN denotes of
T8204 22010-22016 NN denotes 180 bp
T8205 22017-22025 NN denotes fragment
T8206 22026-22030 VB denotes were
T8207 22031-22039 VB denotes observed
T8208 22040-22042 IN denotes in
T8209 22043-22046 DT denotes the
T8210 22047-22054 JJ denotes myeloid
T8211 22055-22059 NN denotes cell
T8212 22060-22064 NN denotes line
T8213 22065-22069 NN denotes U937
T8214 22070-22073 CC denotes and
T8215 22074-22077 DT denotes the
T8216 22078-22085 JJ denotes hepatic
T8217 22086-22090 NN denotes cell
T8218 22091-22096 NN denotes lines
T8219 22097-22102 NN denotes HepG2
T8220 22103-22106 CC denotes and
T8221 22107-22111 NN denotes Huh7
T8222 22112-22113 -LRB- denotes (
T8223 22113-22119 NN denotes Figure
T8224 22120-22122 NN denotes 3C
T8225 22122-22123 -RRB- denotes )
T8226 22123-22124 -COMMA- denotes ,
T8227 22125-22135 VB denotes indicating
T8228 22136-22140 IN denotes that
T8229 22141-22144 DT denotes the
T8230 22145-22149 NN denotes core
T8231 22150-22158 NN denotes promoter
T8232 22159-22161 IN denotes of
T8233 22162-22165 NN denotes A3G
T8234 22166-22168 VB denotes is
T8235 22169-22176 JJ denotes located
T8236 22177-22183 IN denotes within
T8237 22184-22187 DT denotes the
T8238 22188-22194 NN denotes region
T8239 22195-22203 CD denotes −114/+66
T8240 22204-22212 JJ denotes relative
T8241 22213-22215 TO denotes to
T8242 22216-22219 DT denotes the
T8243 22220-22223 NN denotes TSS
T18853 22235-22245 NN denotes Luciferase
T18854 22246-22256 NN denotes activities
T18855 22257-22259 IN denotes of
T18856 22260-22263 NN denotes A3G
T18857 22264-22272 NN denotes promoter
T18858 22273-22283 NN denotes constructs
T18859 22284-22286 IN denotes in
T18860 22287-22296 JJ denotes different
T18861 22297-22301 NN denotes cell
T18862 22302-22308 NN denotes lines.
T18863 22309-22310 -LRB- denotes (
T18864 22310-22311 NN denotes A
T18865 22311-22312 -RRB- denotes )
T18866 22313-22316 NN denotes A3G
T18867 22317-22325 NN denotes promoter
T18868 22326-22328 NN denotes 5′
T18869 22329-22337 NN denotes deletion
T18870 22338-22348 NN denotes constructs
T18871 22349-22351 IN denotes of
T18872 22352-22361 JJ denotes different
T18873 22362-22367 NN denotes sizes
T18874 22368-22372 VB denotes were
T18875 22373-22379 VB denotes cloned
T18876 22380-22384 IN denotes into
T18877 22385-22395 JJ denotes pGL3-Basic
T18878 22396-22406 NN denotes luciferase
T18879 22407-22415 NN denotes reporter
T18880 22416-22424 NN denotes plasmids
T18881 22426-22435 NN denotes Numbering
T18882 22436-22438 VB denotes is
T18883 22439-22447 JJ denotes relative
T18884 22448-22450 TO denotes to
T18885 22451-22454 DT denotes the
T18886 22455-22460 JJ denotes major
T18887 22461-22464 NN denotes TSS
T18888 22466-22467 DT denotes A
T18889 22468-22476 JJ denotes putative
T18890 22477-22484 NN denotes Sp1/Sp3
T18891 22485-22494 NN denotes consensus
T18892 22495-22499 NN denotes site
T18893 22500-22501 -LRB- denotes (
T18894 22501-22505 JJ denotes gray
T18895 22506-22512 NN denotes square
T18896 22512-22513 -RRB- denotes )
T18897 22514-22516 VB denotes is
T18898 22517-22526 VB denotes depicted.
T18899 22527-22528 -LRB- denotes (
T18900 22528-22529 NN denotes B
T18901 22529-22530 -RRB- denotes )
T18902 22531-22538 NN denotes A3.01 T
T18903 22539-22544 NN denotes cells
T18904 22545-22549 VB denotes were
T18905 22550-22561 RB denotes transiently
T18906 22562-22573 VB denotes transfected
T18907 22574-22578 IN denotes with
T18908 22579-22582 DT denotes the
T18909 22583-22586 NN denotes A3G
T18910 22587-22595 NN denotes promoter
T18911 22596-22604 NN denotes deletion
T18912 22605-22615 NN denotes constructs
T18913 22617-22624 NN denotes Numbers
T18914 22625-22627 IN denotes on
T18915 22628-22631 DT denotes the
T18916 22632-22638 NN denotes x-axis
T18917 22639-22644 VB denotes refer
T18918 22645-22647 TO denotes to
T18919 22648-22651 DT denotes the
T18920 22652-22658 NN denotes length
T18921 22659-22661 IN denotes of
T18922 22662-22665 DT denotes the
T18923 22666-22669 NN denotes A3G
T18924 22670-22678 NN denotes promoter
T18925 22679-22688 NN denotes fragments
T18926 22689-22691 IN denotes in
T18927 22692-22695 NN denotes bp.
T18928 22696-22697 -LRB- denotes (
T18929 22697-22698 NN denotes C
T18930 22698-22699 -RRB- denotes )
T18931 22700-22703 NN denotes A3G
T18932 22704-22712 NN denotes promoter
T18933 22713-22721 NN denotes plasmids
T18934 22722-22726 VB denotes were
T18935 22727-22738 VB denotes transfected
T18936 22739-22743 IN denotes into
T18937 22744-22748 NN denotes U937
T18938 22748-22749 -COMMA- denotes ,
T18939 22750-22755 NN denotes HepG2
T18940 22756-22759 CC denotes and
T18941 22760-22764 NN denotes Huh7
T18942 22765-22769 NN denotes cell
T18943 22770-22775 NN denotes lines
T18944 22777-22784 NN denotes Numbers
T18945 22785-22787 IN denotes in
T18946 22788-22791 DT denotes the
T18947 22792-22799 NN denotes legends
T18948 22800-22805 VB denotes refer
T18949 22806-22808 TO denotes to
T18950 22809-22812 DT denotes the
T18951 22813-22819 NN denotes length
T18952 22820-22822 IN denotes of
T18953 22823-22826 DT denotes the
T18954 22827-22830 NN denotes A3G
T18955 22831-22839 NN denotes promoter
T18956 22840-22849 NN denotes fragments
T18957 22850-22852 IN denotes in
T18958 22853-22862 NN denotes bp. After
T18959 22863-22867 NN denotes 48 h
T18960 22867-22868 -COMMA- denotes ,
T18961 22869-22874 NN denotes cells
T18962 22875-22879 VB denotes were
T18963 22880-22889 VB denotes harvested
T18964 22890-22893 IN denotes for
T18965 22894-22904 NN denotes luciferase
T18966 22905-22910 NN denotes assay
T18967 22912-22919 JJ denotes Firefly
T18968 22920-22930 NN denotes luciferase
T18969 22931-22941 NN denotes activities
T18970 22942-22946 VB denotes were
T18971 22947-22957 VB denotes normalized
T18972 22958-22960 TO denotes to
T18973 22961-22972 VB denotes coexpressed
T18974 22973-22980 NN denotes renilla
T18975 22981-22991 NN denotes luciferase
T18976 22992-23002 NN denotes activities
T18977 23004-23008 NN denotes Mean
T18978 23009-23015 NN denotes values
T18979 23016-23017 -LRB- denotes (
T18980 23017-23020 NN denotes ±SD
T18981 23020-23021 -RRB- denotes )
T18982 23022-23024 IN denotes of
T18983 23025-23026 DT denotes a
T18984 23027-23041 JJ denotes representative
T18985 23042-23052 NN denotes experiment
T18986 23053-23062 VB denotes performed
T18987 23063-23065 IN denotes in
T18988 23066-23076 NN denotes triplicate
T18989 23077-23080 VB denotes are
T18990 23081-23086 VB denotes shown
T8864 23089-23092 DT denotes The
T8865 23093-23096 NN denotes A3G
T8866 23097-23105 NN denotes promoter
T8867 23106-23108 VB denotes is
T8868 23109-23112 RB denotes not
T8869 23113-23122 JJ denotes inducible
T8870 23123-23125 IN denotes in
T8871 23126-23127 NN denotes T
T8872 23128-23133 NN denotes cells
T8873 23134-23143 VB denotes According
T8874 23144-23146 TO denotes to
T8875 23147-23150 DT denotes the
T8876 23151-23158 JJ denotes current
T8877 23159-23168 NN denotes knowledge
T8878 23168-23169 -COMMA- denotes ,
T8879 23170-23178 NN denotes APOBEC3G
T8880 23179-23184 VB denotes plays
T8881 23185-23186 DT denotes a
T8882 23187-23191 NN denotes role
T8883 23192-23194 IN denotes in
T8884 23195-23198 DT denotes the
T8885 23199-23205 JJ denotes innate
T8886 23206-23213 NN denotes defence
T8887 23214-23221 IN denotes against
T8888 23222-23231 NN denotes pathogens
T8889 23232-23236 IN denotes like
T8890 23237-23242 NN denotes HIV-1
T8891 23244-23247 DT denotes The
T8892 23248-23254 JJ denotes latter
T8893 23255-23258 VB denotes has
T8894 23259-23266 VB denotes evolved
T8895 23267-23268 DT denotes a
T8896 23269-23278 NN denotes mechanism
T8897 23279-23281 TO denotes to
T8898 23282-23292 VB denotes counteract
T8899 23293-23296 NN denotes A3G
T8900 23297-23305 NN denotes activity
T8901 23306-23308 IN denotes by
T8902 23309-23319 VB denotes expressing
T8903 23320-23323 DT denotes the
T8904 23324-23334 JJ denotes regulatory
T8905 23335-23342 NN denotes protein
T8906 23343-23346 NN denotes Vif
T8907 23347-23348 -LRB- denotes (
T8908 23348-23349 CD denotes 4
T8909 23349-23350 -RRB- denotes )
T8910 23352-23355 NN denotes Vif
T8911 23356-23363 VB denotes induces
T8912 23364-23375 JJ denotes proteasomal
T8913 23376-23387 NN denotes degradation
T8914 23388-23390 IN denotes of
T8915 23391-23394 NN denotes A3G
T8916 23395-23398 CC denotes and
T8917 23399-23411 RB denotes additionally
T8918 23412-23420 VB denotes inhibits
T8919 23421-23424 NN denotes A3G
T8920 23425-23433 NN denotes activity
T8921 23434-23436 IN denotes by
T8922 23437-23444 JJ denotes further
T8923 23445-23455 NN denotes mechanisms
T8924 23456-23457 -LRB- denotes (
T8925 23457-23458 CD denotes 8
T8926 23458-23459 -COMMA- denotes ,
T8927 23460-23465 CD denotes 37–43
T8928 23465-23466 -RRB- denotes )
T8929 23468-23470 TO denotes To
T8930 23471-23482 VB denotes investigate
T8931 23483-23490 IN denotes whether
T8932 23491-23494 DT denotes the
T8933 23495-23509 NN denotes overexpression
T8934 23510-23512 IN denotes of
T8935 23513-23518 NN denotes HIV-1
T8936 23519-23527 NN denotes proteins
T8937 23528-23532 RB denotes also
T8938 23533-23543 VB denotes influences
T8939 23544-23547 NN denotes A3G
T8940 23548-23556 NN denotes promoter
T8941 23557-23565 NN denotes activity
T8942 23565-23566 -COMMA- denotes ,
T8943 23567-23569 PRP denotes we
T8944 23570-23576 CC denotes either
T8945 23577-23586 VB denotes expressed
T8946 23587-23592 NN denotes HIV-1
T8947 23593-23596 NN denotes Vif
T8948 23597-23599 CC denotes or
T8949 23600-23603 DT denotes the
T8950 23604-23609 NN denotes HIV-1
T8951 23610-23613 NN denotes Tat
T8952 23614-23621 NN denotes protein
T8953 23621-23622 -COMMA- denotes ,
T8954 23623-23626 DT denotes the
T8955 23627-23633 JJ denotes latter
T8956 23634-23637 VB denotes has
T8957 23638-23642 VB denotes been
T8958 23643-23648 VB denotes shown
T8959 23649-23651 TO denotes to
T8960 23652-23660 VB denotes activate
T8961 23661-23670 JJ denotes different
T8962 23671-23676 JJ denotes viral
T8963 23677-23680 CC denotes and
T8964 23681-23689 JJ denotes cellular
T8965 23690-23699 NN denotes promoters
T8966 23700-23701 -LRB- denotes (
T8967 23701-23706 CD denotes 44,45
T8968 23706-23707 -RRB- denotes )
T8969 23709-23711 IN denotes In
T8970 23712-23720 NN denotes addition
T8971 23720-23721 -COMMA- denotes ,
T8972 23722-23732 VB denotes increasing
T8973 23733-23740 NN denotes amounts
T8974 23741-23743 IN denotes of
T8975 23744-23747 DT denotes the
T8976 23748-23755 NN denotes plasmid
T8977 23756-23762 NN denotes pNL4-3
T8978 23762-23763 -COMMA- denotes ,
T8979 23764-23774 VB denotes containing
T8980 23775-23778 DT denotes the
T8981 23779-23790 JJ denotes full-length
T8982 23791-23797 NN denotes genome
T8983 23798-23800 IN denotes of
T8984 23801-23806 NN denotes HIV-1
T8985 23806-23807 -COMMA- denotes ,
T8986 23808-23812 VB denotes were
T8987 23813-23824 VB denotes transfected
T8988 23826-23831 DT denotes These
T8989 23832-23842 NN denotes constructs
T8990 23843-23845 CC denotes or
T8991 23846-23849 DT denotes the
T8992 23850-23855 JJ denotes empty
T8993 23856-23862 NN denotes vector
T8994 23863-23871 NN denotes pcDNA3.1
T8995 23872-23876 VB denotes were
T8996 23877-23890 VB denotes cotransfected
T8997 23891-23895 IN denotes with
T8998 23896-23899 DT denotes the
T8999 23900-23907 NN denotes 1025 bp
T9000 23908-23917 NN denotes construct
T9001 23918-23922 IN denotes into
T9002 23923-23930 NN denotes A3.01 T
T9003 23931-23936 NN denotes cells
T9004 23938-23948 NN denotes Luciferase
T9005 23949-23955 NN denotes assays
T9006 23956-23962 VB denotes showed
T9007 23963-23967 IN denotes that
T9008 23968-23971 DT denotes the
T9009 23972-23987 JJ denotes transcriptional
T9010 23988-23996 NN denotes activity
T9011 23997-23999 IN denotes of
T9012 24000-24003 DT denotes the
T9013 24004-24007 NN denotes A3G
T9014 24008-24016 NN denotes promoter
T9015 24017-24020 VB denotes was
T9016 24021-24024 RB denotes not
T9017 24025-24038 RB denotes significantly
T9018 24039-24046 VB denotes altered
T9019 24047-24049 IN denotes in
T9020 24050-24053 DT denotes the
T9021 24054-24062 NN denotes presence
T9022 24063-24065 IN denotes of
T9023 24066-24069 NNP denotes Vif
T9024 24069-24070 -COMMA- denotes ,
T9025 24071-24074 NN denotes Tat
T9026 24075-24077 CC denotes or
T9027 24078-24088 NN denotes HIV-1NL4-3
T9028 24089-24090 -LRB- denotes (
T9029 24090-24096 NN denotes Figure
T9030 24097-24099 NN denotes 4A
T9031 24099-24100 -RRB- denotes )
T9032 24100-24101 -COMMA- denotes ,
T9033 24102-24112 VB denotes suggesting
T9034 24113-24117 IN denotes that
T9035 24118-24123 NN denotes HIV-1
T9036 24124-24126 VB denotes is
T9037 24127-24130 RB denotes not
T9038 24131-24141 VB denotes modulating
T9039 24142-24145 NN denotes A3G
T9040 24146-24156 NN denotes expression
T9041 24157-24159 IN denotes on
T9042 24160-24163 DT denotes the
T9043 24164-24179 JJ denotes transcriptional
T9044 24180-24185 NN denotes level
T19406 24197-24200 NN denotes A3G
T19407 24201-24209 NN denotes promoter
T19408 24210-24220 NN denotes activities
T19409 24221-24226 IN denotes after
T19410 24227-24239 NN denotes coexpression
T19411 24240-24242 IN denotes of
T19412 24243-24248 NN denotes HIV-1
T19413 24249-24257 NN denotes proteins
T19414 24258-24260 CC denotes or
T19415 24261-24270 NN denotes treatment
T19416 24271-24275 IN denotes with
T19417 24276-24279 NN denotes TPA
T19418 24280-24282 CC denotes or
T19419 24283-24295 NN denotes interferons.
T19420 24296-24297 -LRB- denotes (
T19421 24297-24298 NN denotes A
T19422 24298-24299 -RRB- denotes )
T19423 24300-24307 NN denotes A3.01 T
T19424 24308-24313 NN denotes cells
T19425 24314-24318 VB denotes were
T19426 24319-24332 VB denotes cotransfected
T19427 24333-24337 IN denotes with
T19428 24338-24348 JJ denotes pGL3-Basic
T19429 24349-24357 NN denotes reporter
T19430 24358-24365 NN denotes plasmid
T19431 24366-24376 VB denotes containing
T19432 24377-24380 DT denotes the
T19433 24381-24388 NN denotes 1025 bp
T19434 24389-24392 NN denotes A3G
T19435 24393-24401 NN denotes promoter
T19436 24402-24405 CC denotes and
T19437 24406-24410 NN denotes 1 µg
T19438 24411-24413 IN denotes of
T19439 24414-24417 NN denotes Vif
T19440 24418-24428 NN denotes expression
T19441 24429-24436 NN denotes plasmid
T19442 24436-24437 -COMMA- denotes ,
T19443 24438-24442 NN denotes 1 µg
T19444 24443-24446 NN denotes Tat
T19445 24447-24457 NN denotes expression
T19446 24458-24465 NN denotes plasmid
T19447 24466-24468 CC denotes or
T19448 24469-24479 VB denotes increasing
T19449 24480-24487 NN denotes amounts
T19450 24488-24490 IN denotes of
T19451 24491-24501 NN denotes HIV-1NL4-3
T19452 24502-24503 -LRB- denotes (
T19453 24503-24506 CD denotes 0.1
T19454 24506-24507 -COMMA- denotes ,
T19455 24508-24511 CD denotes 0.5
T19456 24512-24515 CC denotes and
T19457 24516-24520 NN denotes 1 µg
T19458 24520-24521 -RRB- denotes )
T19459 24523-24528 IN denotes After
T19460 24529-24533 NN denotes 48 h
T19461 24533-24534 -COMMA- denotes ,
T19462 24535-24540 NN denotes cells
T19463 24541-24545 VB denotes were
T19464 24546-24555 VB denotes harvested
T19465 24556-24559 IN denotes for
T19466 24560-24570 NN denotes luciferase
T19467 24571-24576 NN denotes assay
T19468 24578-24585 JJ denotes Firefly
T19469 24586-24596 NN denotes luciferase
T19470 24597-24607 NN denotes activities
T19471 24608-24612 VB denotes were
T19472 24613-24623 VB denotes normalized
T19473 24624-24626 TO denotes to
T19474 24627-24638 VB denotes coexpressed
T19475 24639-24646 NN denotes renilla
T19476 24647-24657 NN denotes luciferase
T19477 24658-24669 NN denotes activities.
T19478 24670-24671 -LRB- denotes (
T19479 24671-24672 NN denotes B
T19480 24672-24673 -RRB- denotes )
T19481 24674-24681 NN denotes A3.01 T
T19482 24682-24687 NN denotes cells
T19483 24688-24692 VB denotes were
T19484 24693-24704 RB denotes transiently
T19485 24705-24716 VB denotes transfected
T19486 24717-24721 IN denotes with
T19487 24722-24732 JJ denotes pGL3-Basic
T19488 24733-24741 NN denotes reporter
T19489 24742-24749 NN denotes plasmid
T19490 24750-24760 VB denotes containing
T19491 24761-24764 DT denotes the
T19492 24765-24772 NN denotes 1025 bp
T19493 24773-24776 NN denotes A3G
T19494 24777-24785 NN denotes promoter
T19495 24786-24788 CC denotes or
T19496 24789-24793 IN denotes with
T19497 24794-24799 JJ denotes empty
T19498 24800-24806 NN denotes vector
T19499 24808-24815 CD denotes Fifteen
T19500 24816-24820 NN denotes hour
T19501 24821-24827 IN denotes before
T19502 24828-24838 VB denotes harvesting
T19503 24839-24842 IN denotes for
T19504 24843-24853 NN denotes luciferase
T19505 24854-24859 NN denotes assay
T19506 24859-24860 -COMMA- denotes ,
T19507 24861-24862 DT denotes a
T19508 24863-24869 NN denotes subset
T19509 24870-24872 IN denotes of
T19510 24873-24876 DT denotes the
T19511 24877-24881 NN denotes cell
T19512 24882-24889 NN denotes culture
T19513 24890-24893 VB denotes was
T19514 24894-24904 VB denotes stimulated
T19515 24905-24909 IN denotes with
T19516 24910-24918 NN denotes 20 ng/ml
T19517 24919-24922 NN denotes TPA
T19518 24924-24935 CD denotes Forty-eight
T19519 24936-24940 NN denotes hour
T19520 24941-24946 IN denotes after
T19521 24947-24959 NN denotes transfection
T19522 24959-24960 -COMMA- denotes ,
T19523 24961-24971 NN denotes luciferase
T19524 24972-24977 NN denotes assay
T19525 24978-24981 VB denotes was
T19526 24982-24991 VB denotes performed
T19527 24993-25000 JJ denotes Firefly
T19528 25001-25011 NN denotes luciferase
T19529 25012-25022 NN denotes activities
T19530 25023-25027 VB denotes were
T19531 25028-25038 VB denotes normalized
T19532 25039-25041 TO denotes to
T19533 25042-25053 VB denotes coexpressed
T19534 25054-25061 NN denotes renilla
T19535 25062-25072 NN denotes luciferase
T19536 25073-25083 NN denotes activities
T19537 25084-25087 CC denotes and
T19538 25088-25091 DT denotes the
T19539 25092-25098 NN denotes values
T19540 25099-25102 IN denotes for
T19541 25103-25106 DT denotes the
T19542 25107-25112 JJ denotes empty
T19543 25113-25120 NN denotes vectors
T19544 25121-25122 -LRB- denotes (
T19545 25122-25131 JJ denotes untreated
T19546 25132-25135 CC denotes and
T19547 25136-25150 JJ denotes TPA-stimulated
T19548 25150-25151 -RRB- denotes )
T19549 25152-25156 VB denotes were
T19550 25157-25160 VB denotes set
T19551 25161-25163 IN denotes as
T19552 25164-25166 CD denotes 1.
T19553 25167-25168 -LRB- denotes (
T19554 25168-25169 NN denotes C
T19555 25169-25170 -RRB- denotes )
T19556 25171-25178 NN denotes A3.01 T
T19557 25179-25184 NN denotes cells
T19558 25185-25189 VB denotes were
T19559 25190-25201 RB denotes transiently
T19560 25202-25213 VB denotes transfected
T19561 25214-25218 IN denotes with
T19562 25219-25222 DT denotes the
T19563 25223-25226 NN denotes A3G
T19564 25227-25235 NN denotes promoter
T19565 25236-25246 NN denotes constructs
T19566 25247-25249 CC denotes or
T19567 25250-25254 IN denotes with
T19568 25255-25258 DT denotes the
T19569 25259-25280 JJ denotes interferon-responsive
T19570 25281-25289 NN denotes reporter
T19571 25290-25297 NN denotes plasmid
T19572 25298-25306 NN denotes pGL2-CVX
T19573 25307-25308 -LRB- denotes (
T19574 25308-25311 NN denotes GAS
T19575 25311-25312 -RRB- denotes )
T19576 25314-25321 CD denotes Fifteen
T19577 25322-25326 NN denotes hour
T19578 25327-25333 IN denotes before
T19579 25334-25344 VB denotes harvesting
T19580 25345-25348 IN denotes for
T19581 25349-25359 NN denotes luciferase
T19582 25360-25365 NN denotes assay
T19583 25365-25366 -COMMA- denotes ,
T19584 25367-25368 DT denotes a
T19585 25369-25375 NN denotes subset
T19586 25376-25378 IN denotes of
T19587 25379-25382 DT denotes the
T19588 25383-25387 NN denotes cell
T19589 25388-25395 NN denotes culture
T19590 25396-25399 VB denotes was
T19591 25400-25410 VB denotes stimulated
T19592 25411-25415 IN denotes with
T19593 25416-25424 JJ denotes 30 ng/ml
T19594 25425-25430 NN denotes IFN-α
T19595 25431-25433 CC denotes or
T19596 25434-25439 NN denotes IFN-γ
T19597 25441-25452 CD denotes Forty-eight
T19598 25453-25457 NN denotes hour
T19599 25458-25463 IN denotes after
T19600 25464-25476 NN denotes transfection
T19601 25476-25477 -COMMA- denotes ,
T19602 25478-25488 NN denotes luciferase
T19603 25489-25494 NN denotes assay
T19604 25495-25498 VB denotes was
T19605 25499-25508 VB denotes performed
T19606 25510-25517 JJ denotes Firefly
T19607 25518-25528 NN denotes luciferase
T19608 25529-25539 NN denotes activities
T19609 25540-25544 VB denotes were
T19610 25545-25555 VB denotes normalized
T19611 25556-25558 TO denotes to
T19612 25559-25570 VB denotes coexpressed
T19613 25571-25578 NN denotes renilla
T19614 25579-25589 NN denotes luciferase
T19615 25590-25601 NN denotes activities.
T19616 25602-25603 -LRB- denotes (
T19617 25603-25604 NN denotes D
T19618 25604-25605 -RRB- denotes )
T19619 25606-25611 NN denotes HepG2
T19620 25612-25617 NN denotes cells
T19621 25618-25622 VB denotes were
T19622 25623-25627 VB denotes used
T19623 25628-25631 IN denotes for
T19624 25632-25644 NN denotes transfection
T19625 25646-25649 DT denotes The
T19626 25650-25660 NN denotes experiment
T19627 25661-25664 VB denotes was
T19628 25665-25674 VB denotes performed
T19629 25675-25677 IN denotes as
T19630 25678-25687 VB denotes described
T19631 25688-25690 IN denotes in
T19632 25691-25692 -LRB- denotes (
T19633 25692-25693 NN denotes C
T19634 25693-25694 -RRB- denotes )
T19635 25696-25700 NN denotes Mean
T19636 25701-25707 NN denotes values
T19637 25708-25709 -LRB- denotes (
T19638 25709-25712 NN denotes ±SD
T19639 25712-25713 -RRB- denotes )
T19640 25714-25716 IN denotes of
T19641 25717-25731 JJ denotes representative
T19642 25732-25743 NN denotes experiments
T19643 25744-25753 VB denotes performed
T19644 25754-25756 IN denotes in
T19645 25757-25767 NN denotes triplicate
T19646 25768-25771 VB denotes are
T19647 25772-25777 VB denotes shown
T9045 25779-25781 PRP denotes It
T9046 25782-25785 VB denotes has
T9047 25786-25790 VB denotes been
T9048 25791-25796 VB denotes shown
T9049 25797-25801 IN denotes that
T9050 25802-25805 DT denotes the
T9051 25806-25812 NN denotes amount
T9052 25813-25815 IN denotes of
T9053 25816-25819 NN denotes A3G
T9054 25820-25824 NN denotes mRNA
T9055 25825-25827 IN denotes in
T9056 25828-25829 NN denotes T
T9057 25830-25835 NN denotes cells
T9058 25836-25838 VB denotes is
T9059 25839-25848 VB denotes increased
T9060 25849-25851 IN denotes in
T9061 25852-25860 NN denotes response
T9062 25861-25863 TO denotes to
T9063 25864-25873 JJ denotes mitogenic
T9064 25874-25885 NN denotes stimulation
T9065 25886-25890 IN denotes with
T9066 25891-25898 NN denotes phorbol
T9067 25899-25904 NN denotes ester
T9068 25905-25906 -LRB- denotes (
T9069 25906-25911 CD denotes 46–48
T9070 25911-25912 -RRB- denotes )
T9071 25914-25916 IN denotes In
T9072 25917-25925 NN denotes addition
T9073 25925-25926 -COMMA- denotes ,
T9074 25927-25938 NN denotes interferons
T9075 25939-25943 VB denotes have
T9076 25944-25948 VB denotes been
T9077 25949-25958 VB denotes described
T9078 25959-25961 TO denotes to
T9079 25962-25972 VB denotes upregulate
T9080 25973-25976 NN denotes A3G
T9081 25977-25987 NN denotes expression
T9082 25988-25990 IN denotes in
T9083 25991-26002 NN denotes hepatocytes
T9084 26003-26006 CC denotes and
T9085 26007-26018 NN denotes macrophages
T9086 26019-26020 -LRB- denotes (
T9087 26020-26025 CD denotes 46,48
T9088 26025-26026 -RRB- denotes )
T9089 26028-26030 TO denotes To
T9090 26031-26042 VB denotes investigate
T9091 26043-26050 IN denotes whether
T9092 26051-26056 DT denotes these
T9093 26057-26064 NN denotes stimuli
T9094 26065-26074 VB denotes interfere
T9095 26075-26079 IN denotes with
T9096 26080-26083 NN denotes A3G
T9097 26084-26092 NN denotes promoter
T9098 26093-26101 NN denotes activity
T9099 26102-26104 IN denotes in
T9100 26105-26106 NN denotes T
T9101 26107-26112 NN denotes cells
T9102 26112-26113 -COMMA- denotes ,
T9103 26114-26116 PRP denotes we
T9104 26117-26128 VB denotes transfected
T9105 26129-26136 NN denotes A3.01 T
T9106 26137-26142 NN denotes cells
T9107 26143-26147 IN denotes with
T9108 26148-26151 DT denotes the
T9109 26152-26159 NN denotes 1025 bp
T9110 26160-26168 NN denotes promoter
T9111 26169-26171 CC denotes or
T9112 26172-26175 DT denotes the
T9113 26176-26181 JJ denotes empty
T9114 26182-26188 NN denotes vector
T9115 26189-26199 JJ denotes pGL3-Basic
T9116 26200-26201 -LRB- denotes (
T9117 26201-26207 NN denotes vector
T9118 26207-26208 -RRB- denotes )
T9119 26209-26212 CC denotes and
T9120 26213-26220 VB denotes treated
T9121 26221-26224 DT denotes the
T9122 26225-26230 NN denotes cells
T9123 26231-26235 IN denotes with
T9124 26236-26243 NN denotes phorbol
T9125 26244-26249 NN denotes ester
T9126 26250-26251 -LRB- denotes (
T9127 26251-26254 NN denotes TPA
T9128 26254-26255 -RRB- denotes )
T9129 26257-26260 DT denotes The
T9130 26261-26271 NN denotes luciferase
T9131 26272-26277 NN denotes assay
T9132 26278-26284 VB denotes showed
T9133 26285-26289 IN denotes that
T9134 26290-26293 DT denotes the
T9135 26294-26302 JJ denotes ∼15-fold
T9136 26303-26312 VB denotes increased
T9137 26313-26328 JJ denotes transcriptional
T9138 26329-26337 NN denotes activity
T9139 26338-26340 IN denotes of
T9140 26341-26344 DT denotes the
T9141 26345-26352 NN denotes 1025 bp
T9142 26353-26361 NN denotes promoter
T9143 26362-26370 JJ denotes relative
T9144 26371-26373 TO denotes to
T9145 26374-26377 DT denotes the
T9146 26378-26383 JJ denotes empty
T9147 26384-26390 NN denotes vector
T9148 26391-26394 VB denotes was
T9149 26395-26398 RB denotes not
T9150 26399-26406 RB denotes further
T9151 26407-26415 VB denotes enhanced
T9152 26416-26418 IN denotes by
T9153 26419-26422 NN denotes TPA
T9154 26423-26432 NN denotes treatment
T9155 26433-26434 -LRB- denotes (
T9156 26434-26440 NN denotes Figure
T9157 26441-26443 NN denotes 4B
T9158 26443-26444 -RRB- denotes )
T9159 26444-26445 -COMMA- denotes ,
T9160 26446-26454 IN denotes although
T9161 26455-26458 DT denotes the
T9162 26459-26469 JJ denotes functional
T9163 26470-26478 NN denotes activity
T9164 26479-26481 IN denotes of
T9165 26482-26485 NN denotes TPA
T9166 26486-26489 VB denotes was
T9167 26490-26499 VB denotes confirmed
T9168 26500-26502 IN denotes by
T9169 26503-26512 NN denotes induction
T9170 26513-26515 IN denotes of
T9171 26516-26519 DT denotes the
T9172 26520-26524 NN denotes SV40
T9173 26525-26544 JJ denotes promoter-containing
T9174 26545-26553 NN denotes reporter
T9175 26554-26561 NN denotes plasmid
T9176 26562-26574 NN denotes pGL3-Control
T9177 26575-26576 -LRB- denotes (
T9178 26576-26580 NN denotes data
T9179 26581-26584 RB denotes not
T9180 26585-26590 VB denotes shown
T9181 26590-26591 -RRB- denotes )
T9182 26593-26602 RB denotes Similarly
T9183 26602-26603 -COMMA- denotes ,
T9184 26604-26613 NN denotes treatment
T9185 26614-26616 IN denotes of
T9186 26617-26624 NN denotes A3.01 T
T9187 26625-26630 NN denotes cells
T9188 26631-26642 VB denotes transfected
T9189 26643-26647 IN denotes with
T9190 26648-26651 DT denotes the
T9191 26652-26655 NN denotes A3G
T9192 26656-26664 NN denotes promoter
T9193 26665-26673 NN denotes deletion
T9194 26674-26684 NN denotes constructs
T9195 26685-26689 IN denotes with
T9196 26690-26695 NN denotes IFN-α
T9197 26696-26698 CC denotes or
T9198 26699-26704 NN denotes IFN-γ
T9199 26705-26711 VB denotes showed
T9200 26712-26714 DT denotes no
T9201 26715-26721 NN denotes effect
T9202 26722-26723 -LRB- denotes (
T9203 26723-26729 NN denotes Figure
T9204 26730-26732 NN denotes 4C
T9205 26732-26733 -RRB- denotes )
T9206 26735-26748 RB denotes Interestingly
T9207 26748-26749 -COMMA- denotes ,
T9208 26750-26751 DT denotes a
T9209 26752-26759 NN denotes control
T9210 26760-26767 NN denotes plasmid
T9211 26768-26769 -LRB- denotes (
T9212 26769-26777 NN denotes pGL2-CVX
T9213 26777-26778 -RRB- denotes )
T9214 26779-26789 VB denotes containing
T9215 26790-26793 CD denotes two
T9216 26794-26808 JJ denotes IFN-responsive
T9217 26809-26812 NN denotes GAS
T9218 26813-26814 -LRB- denotes (
T9219 26814-26819 NN denotes gamma
T9220 26820-26829 VB denotes activated
T9221 26830-26838 NN denotes sequence
T9222 26838-26839 -RRB- denotes )
T9223 26840-26848 NN denotes elements
T9224 26849-26857 JJ denotes upstream
T9225 26858-26860 IN denotes of
T9226 26861-26864 DT denotes the
T9227 26865-26875 NN denotes luciferase
T9228 26876-26884 NN denotes reporter
T9229 26885-26889 NN denotes gene
T9230 26890-26893 VB denotes was
T9231 26894-26898 RB denotes only
T9232 26899-26906 VB denotes induced
T9233 26907-26909 IN denotes by
T9234 26910-26915 NN denotes IFN-α
T9235 26916-26918 IN denotes in
T9236 26919-26924 DT denotes these
T9237 26925-26930 NN denotes cells
T9238 26931-26932 -LRB- denotes (
T9239 26932-26938 NN denotes Figure
T9240 26939-26941 NN denotes 4C
T9241 26941-26942 -RRB- denotes )
T9242 26944-26949 IN denotes Since
T9243 26950-26953 CD denotes two
T9244 26954-26961 NN denotes reports
T9245 26962-26970 VB denotes describe
T9246 26971-26974 NN denotes A3G
T9247 26975-26987 NN denotes upregulation
T9248 26988-26990 IN denotes by
T9249 26991-27002 NN denotes interferons
T9250 27003-27005 IN denotes in
T9251 27006-27017 NN denotes hepatocytes
T9252 27018-27019 -LRB- denotes (
T9253 27019-27024 CD denotes 47,48
T9254 27024-27025 -RRB- denotes )
T9255 27025-27026 -COMMA- denotes ,
T9256 27027-27029 PRP denotes we
T9257 27030-27042 RB denotes additionally
T9258 27043-27052 VB denotes performed
T9259 27053-27056 DT denotes the
T9260 27057-27067 NN denotes experiment
T9261 27068-27070 IN denotes in
T9262 27071-27074 DT denotes the
T9263 27075-27082 JJ denotes hepatic
T9264 27083-27087 NN denotes cell
T9265 27088-27092 NN denotes line
T9266 27093-27098 NN denotes HepG2
T9267 27100-27102 IN denotes In
T9268 27103-27107 NN denotes line
T9269 27108-27112 IN denotes with
T9270 27113-27118 DT denotes these
T9271 27119-27131 NN denotes publications
T9272 27131-27132 -COMMA- denotes ,
T9273 27133-27135 PRP denotes we
T9274 27136-27144 VB denotes observed
T9275 27145-27147 DT denotes an
T9276 27148-27157 NN denotes induction
T9277 27158-27160 IN denotes of
T9278 27161-27164 DT denotes the
T9279 27165-27168 NN denotes A3G
T9280 27169-27177 NN denotes promoter
T9281 27178-27180 IN denotes by
T9282 27181-27194 RB denotes approximately
T9283 27195-27201 RB denotes 2-fold
T9284 27202-27207 IN denotes after
T9285 27208-27213 NN denotes IFN-α
T9286 27214-27216 CC denotes or
T9287 27217-27222 NN denotes IFN-γ
T9288 27223-27234 NN denotes stimulation
T9289 27235-27236 -LRB- denotes (
T9290 27236-27242 NN denotes Figure
T9291 27243-27245 NN denotes 4D
T9292 27245-27246 -RRB- denotes )
T9293 27247-27251 IN denotes with
T9294 27252-27257 NN denotes IFN-γ
T9295 27258-27263 VB denotes being
T9296 27264-27272 RB denotes slightly
T9297 27273-27277 RB denotes more
T9298 27278-27284 JJ denotes potent
T9299 27286-27289 IN denotes For
T9300 27290-27294 DT denotes both
T9301 27295-27305 NN denotes interferon
T9302 27306-27311 NN denotes types
T9303 27311-27312 -COMMA- denotes ,
T9304 27313-27322 NN denotes induction
T9305 27323-27325 IN denotes of
T9306 27326-27329 NN denotes A3G
T9307 27330-27338 NN denotes promoter
T9308 27339-27347 NN denotes activity
T9309 27348-27351 VB denotes was
T9310 27352-27360 VB denotes observed
T9311 27361-27364 IN denotes for
T9312 27365-27368 DT denotes all
T9313 27369-27377 NN denotes deletion
T9314 27378-27388 NN denotes constructs
T9315 27389-27395 IN denotes except
T9316 27396-27399 IN denotes for
T9317 27400-27403 DT denotes the
T9318 27404-27409 NN denotes 60 bp
T9319 27410-27418 NN denotes fragment
T9320 27418-27419 -COMMA- denotes ,
T9321 27420-27430 VB denotes indicating
T9322 27431-27435 IN denotes that
T9323 27436-27439 DT denotes the
T9324 27440-27451 JJ denotes responsible
T9325 27452-27458 NN denotes region
T9326 27459-27461 VB denotes is
T9327 27462-27469 JJ denotes located
T9328 27470-27476 IN denotes within
T9329 27477-27480 DT denotes the
T9330 27481-27486 NN denotes 60 nt
T9331 27487-27494 JJ denotes present
T9332 27495-27497 IN denotes in
T9333 27498-27501 DT denotes the
T9334 27502-27508 NN denotes 120 bp
T9335 27508-27509 -COMMA- denotes ,
T9336 27510-27513 CC denotes but
T9337 27514-27517 RB denotes not
T9338 27518-27520 IN denotes in
T9339 27521-27524 DT denotes the
T9340 27525-27530 NN denotes 60 bp
T9341 27531-27539 NN denotes fragment
T10345 27542-27543 DT denotes A
T10346 27544-27550 NN denotes GC-box
T10347 27551-27558 JJ denotes located
T10348 27559-27561 IN denotes at
T10349 27562-27570 NN denotes position
T10350 27571-27578 CD denotes −87/−78
T10351 27579-27581 IN denotes of
T10352 27582-27585 DT denotes the
T10353 27586-27589 NN denotes A3G
T10354 27590-27598 NN denotes promoter
T10355 27599-27601 VB denotes is
T10356 27602-27611 JJ denotes important
T10357 27612-27615 IN denotes for
T10358 27616-27631 JJ denotes transcriptional
T10359 27632-27640 NN denotes activity
T10360 27641-27644 DT denotes The
T10361 27645-27653 NN denotes reporter
T10362 27654-27661 NN denotes studies
T10363 27662-27667 VB denotes shown
T10364 27668-27670 IN denotes in
T10365 27671-27677 NN denotes Figure
T10366 27678-27679 CD denotes 3
T10367 27680-27683 VB denotes had
T10368 27684-27696 VB denotes demonstrated
T10369 27697-27698 DT denotes a
T10370 27699-27703 NN denotes drop
T10371 27704-27706 IN denotes in
T10372 27707-27717 NN denotes luciferase
T10373 27718-27726 NN denotes activity
T10374 27727-27732 IN denotes after
T10375 27733-27741 NN denotes deletion
T10376 27742-27744 IN denotes of
T10377 27745-27748 DT denotes the
T10378 27749-27754 NN denotes 30 nt
T10379 27755-27757 IN denotes at
T10380 27758-27761 DT denotes the
T10381 27762-27764 NN denotes 5′
T10382 27765-27768 NN denotes end
T10383 27769-27771 IN denotes of
T10384 27772-27775 DT denotes the
T10385 27776-27782 NN denotes 180 bp
T10386 27783-27787 NN denotes core
T10387 27788-27796 NN denotes promoter
T10388 27798-27800 PRP denotes We
T10389 27801-27810 RB denotes therefore
T10390 27811-27820 VB denotes inspected
T10391 27821-27824 DT denotes the
T10392 27825-27830 JJ denotes 30 bp
T10393 27831-27839 NN denotes sequence
T10394 27840-27847 VB denotes deleted
T10395 27848-27850 IN denotes in
T10396 27851-27854 DT denotes the
T10397 27855-27861 NN denotes 150 bp
T10398 27862-27870 NN denotes fragment
T10399 27871-27874 CC denotes and
T10400 27875-27885 VB denotes identified
T10401 27886-27887 DT denotes a
T10402 27888-27894 NN denotes GC-box
T10403 27895-27897 IN denotes at
T10404 27898-27906 NN denotes position
T10405 27907-27914 CD denotes −87/−78
T10406 27915-27916 -LRB- denotes (
T10407 27916-27919 VB denotes see
T10408 27920-27926 NN denotes Figure
T10409 27927-27928 CD denotes 1
T10410 27928-27929 -RRB- denotes )
T10411 27931-27934 DT denotes The
T10412 27935-27943 NN denotes sequence
T10413 27944-27954 NN denotes TGGGCGGGAC
T10414 27954-27955 -COMMA- denotes ,
T10415 27956-27961 WDT denotes which
T10416 27962-27964 VB denotes is
T10417 27965-27976 VB denotes interrupted
T10418 27977-27979 IN denotes in
T10419 27980-27983 DT denotes the
T10420 27984-27990 NN denotes 150 bp
T10421 27991-27999 NN denotes fragment
T10422 27999-28000 -COMMA- denotes ,
T10423 28001-28011 VB denotes represents
T10424 28012-28013 DT denotes a
T10425 28014-28021 NN denotes variant
T10426 28022-28024 IN denotes of
T10427 28025-28028 DT denotes the
T10428 28029-28030 -LRB- denotes (
T10429 28030-28033 NN denotes G/T
T10430 28033-28034 -RRB- denotes )
T10431 28034-28040 NN denotes GGGCGG
T10432 28040-28041 -LRB- denotes (
T10433 28041-28044 NN denotes G/A
T10434 28044-28045 -RRB- denotes )
T10435 28045-28046 -LRB- denotes (
T10436 28046-28049 NN denotes G/A
T10437 28049-28050 -RRB- denotes )
T10438 28050-28051 -LRB- denotes (
T10439 28051-28054 NN denotes C/T
T10440 28054-28055 -RRB- denotes )
T10441 28056-28065 NN denotes consensus
T10442 28066-28071 NN denotes motif
T10443 28072-28082 VB denotes recognized
T10444 28083-28085 IN denotes by
T10445 28086-28089 NN denotes Sp1
T10446 28090-28093 CC denotes and
T10447 28094-28097 NN denotes Sp3
T10448 28098-28111 NN denotes transcription
T10449 28112-28119 NN denotes factors
T10450 28121-28123 TO denotes To
T10451 28124-28131 VB denotes analyze
T10452 28132-28139 IN denotes whether
T10453 28140-28144 DT denotes this
T10454 28145-28153 JJ denotes putative
T10455 28154-28169 JJ denotes Sp1/Sp3-binding
T10456 28170-28174 NN denotes site
T10457 28175-28183 VB denotes mediates
T10458 28184-28199 JJ denotes transcriptional
T10459 28200-28208 NN denotes activity
T10460 28209-28211 IN denotes of
T10461 28212-28215 DT denotes the
T10462 28216-28222 NN denotes 180 bp
T10463 28223-28227 NN denotes core
T10464 28228-28236 NN denotes promoter
T10465 28236-28237 -COMMA- denotes ,
T10466 28238-28240 PRP denotes we
T10467 28241-28251 VB denotes introduced
T10468 28252-28255 CD denotes two
T10469 28256-28261 NN denotes point
T10470 28262-28271 NN denotes mutations
T10471 28272-28277 WDT denotes which
T10472 28278-28285 VB denotes changed
T10473 28286-28289 DT denotes the
T10474 28290-28298 NN denotes sequence
T10475 28299-28303 IN denotes from
T10476 28304-28314 NN denotes TGGGCGGGAC
T10477 28315-28317 TO denotes to
T10478 28318-28328 NN denotes TGTTCGGGAC
T10479 28329-28330 -LRB- denotes (
T10480 28330-28339 NN denotes mutations
T10481 28340-28345 VB denotes shown
T10482 28346-28348 IN denotes in
T10483 28349-28353 JJ denotes bold
T10484 28353-28354 -RRB- denotes )
T10485 28356-28360 DT denotes This
T10486 28361-28369 VB denotes resulted
T10487 28370-28372 IN denotes in
T10488 28373-28374 DT denotes a
T10489 28375-28377 CD denotes 71
T10490 28377-28378 NN denotes %
T10491 28379-28388 NN denotes reduction
T10492 28389-28391 IN denotes of
T10493 28392-28395 DT denotes the
T10494 28396-28411 JJ denotes transcriptional
T10495 28412-28420 NN denotes activity
T10496 28421-28429 VB denotes compared
T10497 28430-28432 TO denotes to
T10498 28433-28436 DT denotes the
T10499 28437-28447 JJ denotes unmodified
T10500 28448-28454 NN denotes 180 bp
T10501 28455-28463 NN denotes promoter
T10502 28464-28465 -LRB- denotes (
T10503 28465-28471 NN denotes Figure
T10504 28472-28474 NN denotes 5A
T10505 28474-28475 -RRB- denotes )
T10506 28476-28479 CC denotes and
T10507 28480-28484 DT denotes this
T10508 28485-28490 NN denotes value
T10509 28491-28494 VB denotes was
T10510 28495-28499 RB denotes only
T10511 28500-28510 RB denotes marginally
T10512 28511-28517 JJ denotes higher
T10513 28518-28522 IN denotes than
T10514 28523-28526 DT denotes the
T10515 28527-28537 NN denotes luciferase
T10516 28538-28546 NN denotes activity
T10517 28547-28549 IN denotes of
T10518 28550-28553 DT denotes the
T10519 28554-28560 NN denotes 150 bp
T10520 28561-28569 NN denotes fragment
T10521 28569-28570 -COMMA- denotes ,
T10522 28571-28581 VB denotes indicating
T10523 28582-28586 IN denotes that
T10524 28587-28590 DT denotes the
T10525 28591-28601 VB denotes identified
T10526 28602-28607 NN denotes motif
T10527 28608-28610 VB denotes is
T10528 28611-28620 JJ denotes essential
T10529 28621-28624 IN denotes for
T10530 28625-28630 JJ denotes basal
T10531 28631-28639 NN denotes activity
T10532 28640-28642 IN denotes of
T10533 28643-28646 DT denotes the
T10534 28647-28650 NN denotes A3G
T10535 28651-28655 NN denotes core
T10536 28656-28664 NN denotes promoter
T10537 28666-28668 TO denotes To
T10538 28669-28676 RB denotes further
T10539 28677-28684 VB denotes examine
T10540 28685-28688 DT denotes the
T10541 28689-28704 JJ denotes transcriptional
T10542 28705-28712 NN denotes potency
T10543 28713-28715 IN denotes of
T10544 28716-28719 DT denotes the
T10545 28720-28725 JJ denotes 30 nt
T10546 28726-28733 JJ denotes present
T10547 28734-28736 IN denotes in
T10548 28737-28740 DT denotes the
T10549 28741-28747 NN denotes 180 bp
T10550 28748-28756 NN denotes promoter
T10551 28756-28757 -COMMA- denotes ,
T10552 28758-28760 PRP denotes we
T10553 28761-28767 VB denotes cloned
T10554 28768-28771 DT denotes the
T10555 28772-28778 NN denotes region
T10556 28779-28787 CD denotes −114/−85
T10557 28788-28789 -LRB- denotes (
T10558 28789-28799 VB denotes containing
T10559 28800-28803 DT denotes all
T10560 28804-28815 NN denotes nucleotides
T10561 28816-28821 WDT denotes which
T10562 28822-28825 VB denotes are
T10563 28826-28833 VB denotes deleted
T10564 28834-28836 IN denotes in
T10565 28837-28840 DT denotes the
T10566 28841-28847 NN denotes 150 bp
T10567 28848-28856 NN denotes fragment
T10568 28856-28857 -COMMA- denotes ,
T10569 28858-28868 VB denotes designated
T10570 28869-28871 NN denotes E1
T10571 28871-28872 -RRB- denotes )
T10572 28873-28875 CC denotes or
T10573 28876-28879 DT denotes the
T10574 28880-28886 NN denotes region
T10575 28887-28894 CD denotes −92/−63
T10576 28895-28896 -LRB- denotes (
T10577 28896-28906 VB denotes containing
T10578 28907-28910 DT denotes the
T10579 28911-28919 JJ denotes putative
T10580 28920-28927 NN denotes Sp1/Sp3
T10581 28928-28933 NN denotes motif
T10582 28933-28934 -COMMA- denotes ,
T10583 28935-28945 VB denotes designated
T10584 28946-28948 NN denotes E2
T10585 28948-28949 -RRB- denotes )
T10586 28950-28954 IN denotes into
T10587 28955-28958 DT denotes the
T10588 28959-28965 NN denotes vector
T10589 28966-28979 NN denotes pGL3-Promoter
T10590 28980-28981 -LRB- denotes (
T10591 28981-28984 VB denotes see
T10592 28985-28991 NN denotes Figure
T10593 28992-28993 CD denotes 1
T10594 28993-28994 -RRB- denotes )
T10595 28996-29000 DT denotes This
T10596 29001-29007 NN denotes vector
T10597 29008-29016 VB denotes contains
T10598 29017-29018 DT denotes a
T10599 29019-29029 NN denotes luciferase
T10600 29030-29038 NN denotes reporter
T10601 29039-29043 NN denotes gene
T10602 29044-29049 IN denotes under
T10603 29050-29053 DT denotes the
T10604 29054-29061 NN denotes control
T10605 29062-29064 IN denotes of
T10606 29065-29067 DT denotes an
T10607 29068-29072 NN denotes SV40
T10608 29073-29081 NN denotes promoter
T10609 29082-29089 IN denotes without
T10610 29090-29098 NN denotes enhancer
T10611 29099-29108 NN denotes sequences
T10612 29108-29109 -COMMA- denotes ,
T10613 29110-29113 CC denotes and
T10614 29114-29122 JJ denotes putative
T10615 29123-29140 RB denotes transcriptionally
T10616 29141-29147 JJ denotes active
T10617 29148-29157 NN denotes sequences
T10618 29158-29161 MD denotes can
T10619 29162-29164 VB denotes be
T10620 29165-29171 VB denotes cloned
T10621 29172-29180 RB denotes upstream
T10622 29181-29183 IN denotes of
T10623 29184-29187 DT denotes the
T10624 29188-29192 NN denotes SV40
T10625 29193-29201 NN denotes promoter
T10626 29203-29213 NN denotes Luciferase
T10627 29214-29220 NN denotes assays
T10628 29221-29227 VB denotes showed
T10629 29228-29232 IN denotes that
T10630 29233-29236 DT denotes the
T10631 29237-29239 NN denotes E1
T10632 29240-29247 NN denotes element
T10633 29248-29257 VB denotes increased
T10634 29258-29262 NN denotes SV40
T10635 29263-29271 NN denotes promoter
T10636 29272-29280 NN denotes activity
T10637 29281-29285 RB denotes only
T10638 29286-29288 IN denotes by
T10639 29289-29296 JJ denotes ∼2-fold
T10640 29297-29298 -LRB- denotes (
T10641 29298-29304 NN denotes Figure
T10642 29305-29307 NN denotes 5B
T10643 29307-29308 -RRB- denotes )
T10644 29310-29312 IN denotes In
T10645 29313-29321 NN denotes contrast
T10646 29321-29322 -COMMA- denotes ,
T10647 29323-29326 DT denotes the
T10648 29327-29332 NN denotes 30 nt
T10649 29333-29335 IN denotes of
T10650 29336-29338 NN denotes E2
T10651 29339-29347 VB denotes enhanced
T10652 29348-29351 DT denotes the
T10653 29352-29367 JJ denotes transcriptional
T10654 29368-29376 NN denotes activity
T10655 29377-29379 IN denotes of
T10656 29380-29383 DT denotes the
T10657 29384-29388 NN denotes SV40
T10658 29389-29397 NN denotes promoter
T10659 29398-29400 IN denotes by
T10660 29401-29410 JJ denotes ∼4.3-fold
T10661 29410-29411 -COMMA- denotes ,
T10662 29412-29422 VB denotes indicating
T10663 29423-29427 IN denotes that
T10664 29428-29431 DT denotes the
T10665 29432-29438 JJ denotes intact
T10666 29439-29445 NN denotes GC-box
T10667 29446-29453 JJ denotes present
T10668 29454-29456 IN denotes in
T10669 29457-29460 DT denotes the
T10670 29461-29463 NN denotes E2
T10671 29464-29471 NN denotes element
T10672 29472-29475 VB denotes was
T10673 29476-29487 JJ denotes responsible
T10674 29488-29491 IN denotes for
T10675 29492-29495 DT denotes the
T10676 29496-29504 RB denotes strongly
T10677 29505-29513 VB denotes enhanced
T10678 29514-29529 JJ denotes transcriptional
T10679 29530-29538 NN denotes activity
T10680 29539-29541 IN denotes of
T10681 29542-29545 DT denotes the
T10682 29546-29550 NN denotes SV40
T10683 29551-29559 NN denotes promoter
T20231 29571-29572 DT denotes A
T20232 29573-29579 NN denotes GC-box
T20233 29580-29588 VB denotes mediates
T20234 29589-29604 JJ denotes transcriptional
T20235 29605-29613 NN denotes activity
T20236 29614-29616 IN denotes of
T20237 29617-29620 DT denotes the
T20238 29621-29627 NN denotes 180 bp
T20239 29628-29632 NN denotes core
T20240 29633-29642 NN denotes promoter.
T20241 29643-29644 -LRB- denotes (
T20242 29644-29645 NN denotes A
T20243 29645-29646 -RRB- denotes )
T20244 29647-29654 NN denotes A3.01 T
T20245 29655-29660 NN denotes cells
T20246 29661-29665 VB denotes were
T20247 29666-29677 VB denotes transfected
T20248 29678-29682 IN denotes with
T20249 29683-29691 NN denotes reporter
T20250 29692-29699 NN denotes plasmid
T20251 29700-29710 JJ denotes pGL3-Basic
T20252 29711-29721 VB denotes containing
T20253 29722-29725 CD denotes 180
T20254 29725-29726 -COMMA- denotes ,
T20255 29727-29730 CD denotes 150
T20256 29731-29733 CC denotes or
T20257 29734-29740 NN denotes 120 bp
T20258 29741-29743 IN denotes of
T20259 29744-29747 DT denotes the
T20260 29748-29751 NN denotes A3G
T20261 29752-29760 NN denotes promoter
T20262 29762-29765 DT denotes The
T20263 29766-29769 CD denotes two
T20264 29770-29776 NN denotes G-to-T
T20265 29777-29790 NN denotes substitutions
T20266 29791-29801 VB denotes introduced
T20267 29802-29806 IN denotes into
T20268 29807-29810 DT denotes the
T20269 29811-29817 NN denotes GC-box
T20270 29818-29820 IN denotes of
T20271 29821-29824 DT denotes the
T20272 29825-29831 NN denotes 180 bp
T20273 29832-29840 NN denotes fragment
T20274 29841-29842 -LRB- denotes (
T20275 29842-29848 NN denotes 180mut
T20276 29848-29849 -RRB- denotes )
T20277 29850-29853 VB denotes are
T20278 29854-29863 VB denotes specified
T20279 29865-29870 IN denotes After
T20280 29871-29875 NN denotes 48 h
T20281 29875-29876 -COMMA- denotes ,
T20282 29877-29882 NN denotes cells
T20283 29883-29887 VB denotes were
T20284 29888-29897 VB denotes harvested
T20285 29898-29901 IN denotes for
T20286 29902-29912 NN denotes luciferase
T20287 29913-29918 NN denotes assay
T20288 29920-29927 JJ denotes Firefly
T20289 29928-29938 NN denotes luciferase
T20290 29939-29949 NN denotes activities
T20291 29950-29954 VB denotes were
T20292 29955-29965 VB denotes normalized
T20293 29966-29968 TO denotes to
T20294 29969-29980 VB denotes coexpressed
T20295 29981-29988 NN denotes renilla
T20296 29989-29999 NN denotes luciferase
T20297 30000-30010 NN denotes activities
T20298 30012-30016 NN denotes Mean
T20299 30017-30023 NN denotes values
T20300 30024-30025 -LRB- denotes (
T20301 30025-30028 NN denotes ±SD
T20302 30028-30029 -RRB- denotes )
T20303 30030-30032 IN denotes of
T20304 30033-30034 DT denotes a
T20305 30035-30049 JJ denotes representative
T20306 30050-30060 NN denotes experiment
T20307 30061-30070 VB denotes performed
T20308 30071-30073 IN denotes in
T20309 30074-30084 NN denotes triplicate
T20310 30085-30088 VB denotes are
T20311 30089-30095 NN denotes shown.
T20312 30096-30097 -LRB- denotes (
T20313 30097-30098 NN denotes B
T20314 30098-30099 -RRB- denotes )
T20315 30100-30113 NN denotes pGL3-Promoter
T20316 30114-30122 NN denotes reporter
T20317 30123-30131 NN denotes plasmids
T20318 30132-30142 VB denotes containing
T20319 30143-30146 DT denotes the
T20320 30147-30154 NN denotes regions
T20321 30155-30157 NN denotes E1
T20322 30158-30160 CC denotes or
T20323 30161-30163 NN denotes E2
T20324 30164-30165 -LRB- denotes (
T20325 30165-30168 VB denotes see
T20326 30169-30175 NN denotes Figure
T20327 30176-30177 CD denotes 1
T20328 30177-30178 -RRB- denotes )
T20329 30179-30187 RB denotes upstream
T20330 30188-30190 IN denotes of
T20331 30191-30194 DT denotes the
T20332 30195-30199 NN denotes SV40
T20333 30200-30208 NN denotes promoter
T20334 30209-30213 VB denotes were
T20335 30214-30225 VB denotes transfected
T20336 30226-30230 IN denotes into
T20337 30231-30238 NN denotes A3.01 T
T20338 30239-30244 NN denotes cells
T20339 30246-30253 JJ denotes Firefly
T20340 30254-30264 NN denotes luciferase
T20341 30265-30275 NN denotes activities
T20342 30276-30281 IN denotes after
T20343 30282-30286 NN denotes 48 h
T20344 30287-30291 VB denotes were
T20345 30292-30302 VB denotes normalized
T20346 30303-30305 TO denotes to
T20347 30306-30317 VB denotes coexpressed
T20348 30318-30325 NN denotes renilla
T20349 30326-30336 NN denotes luciferase
T20350 30337-30347 NN denotes activities
T20351 30349-30353 NN denotes Mean
T20352 30354-30360 NN denotes values
T20353 30361-30362 -LRB- denotes (
T20354 30362-30365 NN denotes ±SD
T20355 30365-30366 -RRB- denotes )
T20356 30367-30369 IN denotes of
T20357 30370-30371 DT denotes a
T20358 30372-30386 JJ denotes representative
T20359 30387-30397 NN denotes experiment
T20360 30398-30407 VB denotes performed
T20361 30408-30410 IN denotes in
T20362 30411-30421 NN denotes triplicate
T20363 30422-30425 VB denotes are
T20364 30426-30431 VB denotes shown
T11431 30468-30472 VB denotes bind
T11432 30473-30475 TO denotes to
T11433 30476-30479 DT denotes the
T11434 30480-30486 NN denotes GC-box
T11435 30487-30489 IN denotes at
T11436 30490-30498 NN denotes position
T11437 30499-30506 CD denotes −87/−78
T11438 30507-30509 IN denotes of
T11439 30510-30513 DT denotes the
T11440 30514-30517 NN denotes A3G
T11441 30518-30526 NN denotes promoter
T11442 30527-30529 TO denotes To
T11443 30530-30541 VB denotes investigate
T11444 30542-30549 IN denotes whether
T11445 30550-30553 DT denotes the
T11446 30554-30560 NN denotes GC-box
T11447 30561-30571 VB denotes represents
T11448 30572-30573 DT denotes a
T11449 30574-30581 VB denotes binding
T11450 30582-30586 NN denotes site
T11451 30587-30590 IN denotes for
T11452 30591-30594 DT denotes the
T11453 30595-30608 NN denotes transcription
T11454 30609-30616 NN denotes factors
T11455 30617-30620 NN denotes Sp1
T11456 30621-30624 CC denotes and
T11457 30625-30628 NN denotes Sp3
T11458 30628-30629 -COMMA- denotes ,
T11459 30630-30632 PRP denotes we
T11460 30633-30642 VB denotes performed
T11461 30643-30647 NN denotes EMSA
T11462 30648-30656 NN denotes analyses
T11463 30657-30661 IN denotes with
T11464 30662-30669 JJ denotes nuclear
T11465 30670-30678 NN denotes extracts
T11466 30679-30687 VB denotes isolated
T11467 30688-30692 IN denotes from
T11468 30693-30700 NN denotes A3.01 T
T11469 30701-30706 NN denotes cells
T11470 30708-30710 IN denotes As
T11471 30711-30717 NN denotes probes
T11472 30717-30718 -COMMA- denotes ,
T11473 30719-30721 PRP denotes we
T11474 30722-30735 RB denotes radioactively
T11475 30736-30743 VB denotes labeled
T11476 30744-30747 DT denotes the
T11477 30748-30758 JJ denotes unmodified
T11478 30759-30761 NN denotes E2
T11479 30762-30770 NN denotes sequence
T11480 30771-30772 -LRB- denotes (
T11481 30772-30783 NN denotes nucleotides
T11482 30784-30791 CD denotes −92/−63
T11483 30792-30794 IN denotes of
T11484 30795-30798 DT denotes the
T11485 30799-30802 NN denotes A3G
T11486 30803-30811 NN denotes promoter
T11487 30811-30812 -COMMA- denotes ,
T11488 30813-30818 NN denotes probe
T11489 30819-30829 VB denotes designated
T11490 30830-30839 NN denotes APO-Sp1/3
T11491 30839-30840 -RRB- denotes )
T11492 30841-30843 CC denotes or
T11493 30844-30847 DT denotes the
T11494 30848-30852 JJ denotes same
T11495 30853-30859 NN denotes region
T11496 30860-30868 VB denotes carrying
T11497 30869-30872 DT denotes the
T11498 30873-30876 CD denotes two
T11499 30877-30882 NN denotes point
T11500 30883-30892 NN denotes mutations
T11501 30893-30902 VB denotes described
T11502 30903-30908 IN denotes above
T11503 30909-30910 -LRB- denotes (
T11504 30910-30915 NN denotes probe
T11505 30916-30926 VB denotes designated
T11506 30927-30939 NN denotes APO-Sp1/3mut
T11507 30939-30940 -RRB- denotes )
T11508 30942-30944 IN denotes As
T11509 30945-30952 NN denotes control
T11510 30952-30953 -COMMA- denotes ,
T11511 30954-30956 PRP denotes we
T11512 30957-30961 VB denotes used
T11513 30962-30963 DT denotes a
T11514 30964-30976 RB denotes commercially
T11515 30977-30986 JJ denotes available
T11516 30987-30990 NN denotes Sp1
T11517 30991-31000 NN denotes consensus
T11518 31001-31016 NN denotes oligonucleotide
T11519 31017-31018 -LRB- denotes (
T11520 31018-31025 NN denotes Sp1cons
T11521 31025-31026 -RRB- denotes )
T11522 31026-31027 -COMMA- denotes ,
T11523 31028-31033 WDT denotes which
T11524 31034-31036 VB denotes is
T11525 31037-31042 VB denotes known
T11526 31043-31045 TO denotes to
T11527 31046-31048 VB denotes be
T11528 31049-31059 VB denotes recognized
T11529 31060-31062 IN denotes by
T11530 31063-31066 NN denotes Sp1
T11531 31067-31080 NN denotes transcription
T11532 31081-31088 NN denotes factors
T11533 31090-31094 CD denotes Four
T11534 31095-31106 NN denotes DNA–protein
T11535 31107-31116 NN denotes complexes
T11536 31117-31121 VB denotes were
T11537 31122-31130 VB denotes observed
T11538 31131-31133 IN denotes in
T11539 31134-31137 DT denotes the
T11540 31138-31146 NN denotes presence
T11541 31147-31149 IN denotes of
T11542 31150-31153 DT denotes the
T11543 31154-31163 NN denotes APO-Sp1/3
T11544 31164-31169 NN denotes probe
T11545 31170-31171 -LRB- denotes (
T11546 31171-31177 NN denotes Figure
T11547 31178-31180 NN denotes 6A
T11548 31180-31181 -RRB- denotes )
T11549 31183-31186 DT denotes The
T11550 31187-31192 JJ denotes upper
T11551 31193-31196 CD denotes two
T11552 31197-31206 NN denotes complexes
T11553 31207-31211 VB denotes were
T11554 31212-31220 JJ denotes specific
T11555 31221-31226 IN denotes since
T11556 31227-31231 PRP denotes they
T11557 31232-31243 VB denotes disappeared
T11558 31244-31246 IN denotes in
T11559 31247-31250 DT denotes the
T11560 31251-31259 NN denotes presence
T11561 31260-31262 IN denotes of
T11562 31263-31264 DT denotes a
T11563 31265-31272 JJ denotes 30-fold
T11564 31273-31278 JJ denotes molar
T11565 31279-31285 NN denotes excess
T11566 31286-31288 IN denotes of
T11567 31289-31298 JJ denotes unlabeled
T11568 31299-31308 NN denotes APO-Sp1/3
T11569 31309-31314 NN denotes probe
T11570 31315-31316 -LRB- denotes (
T11571 31316-31322 NN denotes Figure
T11572 31323-31325 NN denotes 6A
T11573 31325-31326 -COMMA- denotes ,
T11574 31327-31331 NN denotes lane
T11575 31332-31333 CD denotes 7
T11576 31333-31334 -RRB- denotes )
T11577 31336-31343 JJ denotes Further
T11578 31344-31356 NN denotes confirmation
T11579 31357-31359 IN denotes of
T11580 31360-31363 DT denotes the
T11581 31364-31375 NN denotes specificity
T11582 31376-31378 IN denotes of
T11583 31379-31384 DT denotes these
T11584 31385-31396 NN denotes DNA–protein
T11585 31397-31406 NN denotes complexes
T11586 31407-31410 VB denotes was
T11587 31411-31423 VB denotes demonstrated
T11588 31424-31426 IN denotes by
T11589 31427-31430 DT denotes the
T11590 31431-31440 NN denotes inability
T11591 31441-31443 IN denotes of
T11592 31444-31447 DT denotes the
T11593 31448-31457 JJ denotes unlabeled
T11594 31458-31470 NN denotes APO-Sp1/3mut
T11595 31471-31476 NN denotes probe
T11596 31477-31479 TO denotes to
T11597 31480-31487 VB denotes abolish
T11598 31488-31495 NN denotes binding
T11599 31496-31497 -LRB- denotes (
T11600 31497-31503 NN denotes Figure
T11601 31504-31506 NN denotes 6A
T11602 31506-31507 -COMMA- denotes ,
T11603 31508-31513 NN denotes lanes
T11604 31514-31516 CD denotes 12
T11605 31517-31520 CC denotes and
T11606 31521-31523 CD denotes 13
T11607 31523-31524 -RRB- denotes )
T11608 31526-31528 IN denotes As
T11609 31529-31537 VB denotes expected
T11610 31537-31538 -COMMA- denotes ,
T11611 31539-31542 DT denotes the
T11612 31543-31546 CD denotes two
T11613 31547-31555 JJ denotes specific
T11614 31556-31565 NN denotes complexes
T11615 31566-31570 VB denotes were
T11616 31571-31575 RB denotes also
T11617 31576-31583 JJ denotes present
T11618 31584-31586 IN denotes in
T11619 31587-31590 DT denotes the
T11620 31591-31595 NN denotes case
T11621 31596-31598 IN denotes of
T11622 31599-31602 DT denotes the
T11623 31603-31610 NN denotes Sp1cons
T11624 31611-31618 NN denotes control
T11625 31619-31624 NN denotes probe
T11626 31625-31626 -LRB- denotes (
T11627 31626-31632 NN denotes Figure
T11628 31633-31635 NN denotes 6A
T11629 31635-31636 -COMMA- denotes ,
T11630 31637-31642 NN denotes lanes
T11631 31643-31644 CD denotes 2
T11632 31645-31648 CC denotes and
T11633 31649-31650 CD denotes 3
T11634 31650-31651 -RRB- denotes )
T11635 31653-31655 IN denotes In
T11636 31656-31664 NN denotes contrast
T11637 31664-31665 -COMMA- denotes ,
T11638 31666-31670 NN denotes none
T11639 31671-31673 IN denotes of
T11640 31674-31679 DT denotes these
T11641 31680-31688 JJ denotes specific
T11642 31689-31698 NN denotes complexes
T11643 31699-31702 VB denotes was
T11644 31703-31711 VB denotes observed
T11645 31712-31716 WRB denotes when
T11646 31717-31720 DT denotes the
T11647 31721-31728 VB denotes mutated
T11648 31729-31734 NN denotes probe
T11649 31735-31738 VB denotes was
T11650 31739-31743 VB denotes used
T11651 31744-31745 -LRB- denotes (
T11652 31745-31751 NN denotes Figure
T11653 31752-31754 NN denotes 6A
T11654 31754-31755 -COMMA- denotes ,
T11655 31756-31761 NN denotes lanes
T11656 31762-31764 CD denotes 10
T11657 31765-31768 CC denotes and
T11658 31769-31771 CD denotes 11
T11659 31771-31772 -RRB- denotes )
T11660 31772-31773 -COMMA- denotes ,
T11661 31774-31784 VB denotes confirming
T11662 31785-31789 IN denotes that
T11663 31790-31797 NN denotes protein
T11664 31798-31805 NN denotes binding
T11665 31806-31809 VB denotes was
T11666 31810-31819 JJ denotes dependent
T11667 31820-31822 IN denotes on
T11668 31823-31826 DT denotes the
T11669 31827-31837 VB denotes identified
T11670 31838-31844 NN denotes GC-box
T11671 31846-31848 IN denotes In
T11672 31849-31854 NN denotes order
T11673 31855-31857 TO denotes to
T11674 31858-31870 VB denotes characterize
T11675 31871-31874 DT denotes the
T11676 31875-31884 NN denotes complexes
T11677 31884-31885 -COMMA- denotes ,
T11678 31886-31888 PRP denotes we
T11679 31889-31898 VB denotes performed
T11680 31899-31909 NN denotes supershift
T11681 31910-31921 NN denotes experiments
T11682 31922-31927 VB denotes using
T11683 31928-31932 NN denotes Sp1-
T11684 31933-31936 CC denotes and
T11685 31937-31949 JJ denotes Sp3-specific
T11686 31950-31960 NN denotes antibodies
T11687 31962-31965 DT denotes The
T11688 31966-31971 NN denotes upper
T11689 31972-31974 IN denotes of
T11690 31975-31978 DT denotes the
T11691 31979-31988 NN denotes complexes
T11692 31989-31993 WDT denotes that
T11693 31994-32002 VB denotes appeared
T11694 32003-32005 IN denotes in
T11695 32006-32017 NN denotes combination
T11696 32018-32022 IN denotes with
T11697 32023-32026 DT denotes the
T11698 32027-32034 NN denotes Sp1cons
T11699 32035-32037 CC denotes or
T11700 32038-32047 NN denotes APO-Sp1/3
T11701 32048-32054 NN denotes probes
T11702 32054-32055 -COMMA- denotes ,
T11703 32056-32063 VB denotes shifted
T11704 32064-32066 IN denotes in
T11705 32067-32070 DT denotes the
T11706 32071-32079 NN denotes presence
T11707 32080-32082 IN denotes of
T11708 32083-32086 DT denotes the
T11709 32087-32090 NN denotes Sp1
T11710 32091-32099 NN denotes antibody
T11711 32100-32101 -LRB- denotes (
T11712 32101-32107 NN denotes Figure
T11713 32108-32110 NN denotes 6B
T11714 32110-32111 -COMMA- denotes ,
T11715 32112-32117 NN denotes lanes
T11716 32118-32119 CD denotes 3
T11717 32120-32123 CC denotes and
T11718 32124-32125 CD denotes 7
T11719 32125-32126 -RRB- denotes )
T11720 32126-32127 -COMMA- denotes ,
T11721 32128-32135 IN denotes whereas
T11722 32136-32139 DT denotes the
T11723 32140-32145 JJ denotes lower
T11724 32146-32153 NN denotes complex
T11725 32154-32161 VB denotes shifted
T11726 32162-32164 IN denotes in
T11727 32165-32168 DT denotes the
T11728 32169-32177 NN denotes presence
T11729 32178-32180 IN denotes of
T11730 32181-32184 DT denotes the
T11731 32185-32188 NN denotes Sp3
T11732 32189-32197 NN denotes antibody
T11733 32198-32199 -LRB- denotes (
T11734 32199-32205 NN denotes Figure
T11735 32206-32208 NN denotes 6B
T11736 32208-32209 -COMMA- denotes ,
T11737 32210-32215 NN denotes lanes
T11738 32216-32217 CD denotes 4
T11739 32218-32221 CC denotes and
T11740 32222-32223 CD denotes 8
T11741 32223-32224 -RRB- denotes )
T11742 32226-32231 VB denotes Taken
T11743 32232-32240 RB denotes together
T11744 32240-32241 -COMMA- denotes ,
T11745 32242-32245 DT denotes the
T11746 32246-32250 NN denotes EMSA
T11747 32251-32263 VB denotes demonstrated
T11748 32264-32268 IN denotes that
T11749 32269-32272 DT denotes the
T11750 32273-32279 NN denotes GC-box
T11751 32280-32287 JJ denotes located
T11752 32288-32290 IN denotes on
T11753 32291-32294 DT denotes the
T11754 32295-32298 NN denotes A3G
T11755 32299-32303 NN denotes core
T11756 32304-32312 NN denotes promoter
T11757 32313-32319 VB denotes serves
T11758 32320-32322 IN denotes as
T11759 32323-32324 DT denotes a
T11760 32325-32332 VB denotes binding
T11761 32333-32337 NN denotes site
T11762 32338-32341 IN denotes for
T11763 32342-32345 NN denotes Sp1
T11764 32346-32349 CC denotes and
T11765 32350-32353 NN denotes Sp3
T20720 32365-32368 NN denotes Sp1
T20721 32369-32372 CC denotes and
T20722 32373-32376 NN denotes Sp3
T20723 32377-32381 VB denotes bind
T20724 32382-32384 TO denotes to
T20725 32385-32388 DT denotes the
T20726 32389-32395 NN denotes GC-box
T20727 32396-32403 JJ denotes present
T20728 32404-32406 IN denotes in
T20729 32407-32410 DT denotes the
T20730 32411-32414 NN denotes A3G
T20731 32415-32424 NN denotes promoter.
T20732 32425-32426 -LRB- denotes (
T20733 32426-32427 NN denotes A
T20734 32427-32428 -RRB- denotes )
T20735 32429-32436 JJ denotes Nuclear
T20736 32437-32445 NN denotes extracts
T20737 32446-32448 IN denotes of
T20738 32449-32456 NN denotes A3.01 T
T20739 32457-32462 NN denotes cells
T20740 32463-32467 VB denotes were
T20741 32468-32477 VB denotes incubated
T20742 32478-32482 IN denotes with
T20743 32483-32484 DT denotes a
T20744 32485-32496 JJ denotes 32P-labeled
T20745 32497-32507 JJ denotes commercial
T20746 32508-32511 NN denotes Sp1
T20747 32512-32527 NN denotes oligonucleotide
T20748 32528-32533 NN denotes probe
T20749 32534-32535 -LRB- denotes (
T20750 32535-32542 NN denotes Sp1cons
T20751 32542-32543 -RRB- denotes )
T20752 32544-32546 CC denotes or
T20753 32547-32554 VB denotes labeled
T20754 32555-32561 NN denotes probes
T20755 32562-32572 JJ denotes homologous
T20756 32573-32575 TO denotes to
T20757 32576-32579 DT denotes the
T20758 32580-32590 JJ denotes unmodified
T20759 32591-32593 CC denotes or
T20760 32594-32601 VB denotes mutated
T20761 32602-32604 NN denotes E2
T20762 32605-32611 NN denotes region
T20763 32612-32613 -LRB- denotes (
T20764 32613-32616 VB denotes see
T20765 32617-32623 NN denotes Figure
T20766 32624-32625 CD denotes 1
T20767 32625-32626 -RRB- denotes )
T20768 32627-32629 IN denotes of
T20769 32630-32633 DT denotes the
T20770 32634-32637 NN denotes A3G
T20771 32638-32646 NN denotes promoter
T20772 32647-32648 -LRB- denotes (
T20773 32648-32657 NN denotes APO-Sp1/3
T20774 32658-32661 CC denotes and
T20775 32662-32674 NN denotes APO-Sp1/3mut
T20776 32674-32675 -RRB- denotes )
T20777 32677-32688 NN denotes Protein–DNA
T20778 32689-32698 NN denotes complexes
T20779 32699-32703 VB denotes were
T20780 32704-32713 VB denotes separated
T20781 32714-32716 IN denotes by
T20782 32717-32731 NN denotes polyacrylamide
T20783 32732-32747 NN denotes electrophoresis
T20784 32748-32751 CC denotes and
T20785 32752-32760 VB denotes detected
T20786 32761-32763 IN denotes by
T20787 32764-32779 NN denotes autoradiography
T20788 32781-32785 NN denotes EMSA
T20789 32786-32789 VB denotes was
T20790 32790-32799 VB denotes performed
T20791 32800-32804 IN denotes with
T20792 32805-32806 DT denotes a
T20793 32807-32809 NN denotes 1-
T20794 32810-32812 CC denotes or
T20795 32813-32820 RB denotes 30-fold
T20796 32821-32826 JJ denotes molar
T20797 32827-32833 NN denotes excess
T20798 32834-32836 IN denotes of
T20799 32837-32846 JJ denotes unlabeled
T20800 32847-32856 NN denotes APO-Sp1/3
T20801 32857-32862 NN denotes probe
T20802 32863-32864 -LRB- denotes (
T20803 32864-32874 NN denotes competitor
T20804 32874-32875 -COMMA- denotes ,
T20805 32876-32881 NN denotes lanes
T20806 32882-32883 CD denotes 6
T20807 32884-32887 CC denotes and
T20808 32888-32889 CD denotes 7
T20809 32889-32890 -RRB- denotes )
T20810 32891-32893 CC denotes or
T20811 32894-32906 NN denotes APO-Sp1/3mut
T20812 32907-32912 NN denotes probe
T20813 32913-32914 -LRB- denotes (
T20814 32914-32924 NN denotes competitor
T20815 32925-32929 NN denotes mut.
T20816 32929-32930 -COMMA- denotes ,
T20817 32931-32936 NN denotes lanes
T20818 32937-32939 CD denotes 12
T20819 32940-32943 CC denotes and
T20820 32944-32946 CD denotes 13
T20821 32946-32947 -RRB- denotes )
T20822 32947-32948 -LRB- denotes .
T20823 32949-32950 NN denotes (
T20824 32950-32951 -RRB- denotes B
T20825 32951-32955 NN denotes ) Sp
T20826 32955-32958 CC denotes 1-
T20827 32958-32970 JJ denotes and Sp3-spec
T20828 32970-32980 NN denotes ific antib
T20829 32980-32984 VB denotes odie
T20830 32984-32989 VB denotes s wer
T20831 32989-32991 TO denotes e
T20832 32991-32994 DT denotes add
T20833 32994-32998 NN denotes ed t
T20834 32998-33007 NN denotes o the EMS
T20835 33007-33016 VB denotes A reactio
T20836 33016-33018 IN denotes ns
T20837 33019-33020 DT denotes r
T20838 33020-33030 NN denotes esulting i
T20839 33030-33031 -LRB- denotes n
T20840 33032-33034 NN denotes a
T20841 33034-33035 -RRB- denotes s
T20842 33035-33037 IN denotes up
T20843 33037-33040 DT denotes ers
T20844 33040-33050 JJ denotes hift (ss)
T20845 33050-33072 JJ denotes of the respective anti
T20846 33072-33081 NN denotes body–prot
T20847 33081-33082 -LRB- denotes e
T20848 33082-33087 NN denotes in–ol
T20849 33087-33088 CD denotes i
T20850 33088-33089 -COMMA- denotes g
T20851 33089-33090 CD denotes o
T20852 33091-33092 -COMMA- denotes c
T20853 33092-33093 CD denotes o
T20854 33093-33094 -COMMA- denotes m
T20855 33094-33095 CD denotes p
T20856 33095-33096 -COMMA- denotes l
T20857 33096-33098 CD denotes ex
T20858 33098-33099 -COMMA- denotes e
T20859 33099-33101 CD denotes s
T20860 33101-33102 -RRB- denotes (
T20861 33102-33103 -LRB- denotes l
T20862 33103-33104 NN denotes a
T20863 33104-33105 -RRB- denotes n
T20864 33105-33109 NN denotes es 3
T20865 33109-33114 NN denotes , 4,
T20866 33114-33117 VB denotes 7,
T20867 33117-33126 VB denotes 8, 11, 12
T20868 33126-33130 IN denotes ). (
T20869 33130-33133 NN denotes C)
T20870 33133-33137 IN denotes ChIP
T20871 33138-33145 NN denotes assay w
T20872 33145-33150 NN denotes as pe
T20873 33187-33206 NN denotes Immunoprecipitation
T20874 33207-33210 VB denotes was
T20875 33211-33220 VB denotes performed
T20876 33221-33225 IN denotes with
T20877 33226-33236 NN denotes antibodies
T20878 33237-33244 IN denotes against
T20879 33245-33248 NN denotes Sp1
T20880 33248-33249 -COMMA- denotes ,
T20881 33250-33253 NN denotes Sp3
T20882 33254-33256 CC denotes or
T20883 33257-33262 NN denotes actin
T20884 33264-33267 NN denotes PCR
T20885 33268-33274 NN denotes primer
T20886 33275-33280 NN denotes pairs
T20887 33281-33289 JJ denotes specific
T20888 33290-33293 IN denotes for
T20889 33294-33297 DT denotes the
T20890 33298-33301 NN denotes A3G
T20891 33302-33310 NN denotes promoter
T20892 33311-33312 -LRB- denotes (
T20893 33312-33317 JJ denotes upper
T20894 33318-33323 NN denotes panel
T20895 33323-33324 -RRB- denotes )
T20896 33325-33327 CC denotes or
T20897 33328-33331 DT denotes the
T20898 33332-33335 NN denotes A3G
T20899 33336-33340 NN denotes gene
T20900 33341-33342 -LRB- denotes (
T20901 33342-33347 JJ denotes lower
T20902 33348-33353 NN denotes panel
T20903 33353-33354 -RRB- denotes )
T20904 33355-33359 VB denotes were
T20905 33360-33364 VB denotes used
T20906 33366-33368 IN denotes As
T20907 33369-33377 JJ denotes positive
T20908 33378-33386 NN denotes controls
T20909 33386-33387 -COMMA- denotes ,
T20910 33388-33391 DT denotes the
T20911 33392-33399 JJ denotes sheared
T20912 33400-33403 CC denotes and
T20913 33404-33416 JJ denotes cross-linked
T20914 33417-33420 NN denotes DNA
T20915 33421-33427 IN denotes before
T20916 33428-33431 DT denotes the
T20917 33432-33451 NN denotes immunoprecipitation
T20918 33452-33456 NN denotes step
T20919 33457-33458 -LRB- denotes (
T20920 33458-33463 NN denotes input
T20921 33463-33464 -RRB- denotes )
T20922 33465-33467 CC denotes or
T20923 33468-33469 DT denotes a
T20924 33470-33477 NN denotes plasmid
T20925 33478-33486 VB denotes carrying
T20926 33487-33490 DT denotes the
T20927 33491-33497 NN denotes target
T20928 33498-33506 NN denotes sequence
T20929 33507-33508 -LRB- denotes (
T20930 33508-33515 NN denotes plasmid
T20931 33515-33516 -RRB- denotes )
T20932 33517-33520 VB denotes was
T20933 33521-33525 VB denotes used
T20934 33526-33528 IN denotes as
T20935 33529-33537 NN denotes template
T11766 33539-33541 TO denotes To
T11767 33542-33546 VB denotes show
T11768 33547-33554 NN denotes binding
T11769 33555-33557 IN denotes of
T11770 33558-33561 NN denotes Sp1
T11771 33562-33565 CC denotes and
T11772 33566-33569 NN denotes Sp3
T11773 33570-33577 NN denotes factors
T11774 33578-33582 RB denotes also
T11775 33583-33585 IN denotes in
T11776 33586-33589 DT denotes the
T11777 33590-33597 NN denotes context
T11778 33598-33600 IN denotes of
T11779 33601-33604 DT denotes the
T11780 33605-33615 JJ denotes endogenous
T11781 33616-33619 NN denotes A3G
T11782 33620-33628 NN denotes promoter
T11783 33628-33629 -COMMA- denotes ,
T11784 33630-33631 DT denotes a
T11785 33632-33641 NN denotes chromatin
T11786 33642-33661 NN denotes immunoprecipitation
T11787 33662-33663 -LRB- denotes (
T11788 33663-33667 NN denotes ChIP
T11789 33667-33668 -RRB- denotes )
T11790 33669-33674 NN denotes assay
T11791 33675-33678 VB denotes was
T11792 33679-33688 VB denotes performed
T11793 33690-33693 NN denotes Sp1
T11794 33694-33697 CC denotes and
T11795 33698-33701 NN denotes Sp3
T11796 33702-33712 NN denotes antibodies
T11797 33712-33713 -COMMA- denotes ,
T11798 33714-33717 CC denotes but
T11799 33718-33721 RB denotes not
T11800 33722-33724 DT denotes an
T11801 33725-33730 NN denotes actin
T11802 33731-33739 NN denotes antibody
T11803 33739-33740 -COMMA- denotes ,
T11804 33741-33759 VB denotes immunoprecipitated
T11805 33760-33763 DT denotes the
T11806 33764-33767 NN denotes A3G
T11807 33768-33776 NN denotes promoter
T11808 33777-33779 IN denotes in
T11809 33780-33787 NN denotes A3.01 T
T11810 33788-33793 NN denotes cells
T11811 33794-33795 -LRB- denotes (
T11812 33795-33801 NN denotes Figure
T11813 33802-33804 NN denotes 6C
T11814 33804-33805 -COMMA- denotes ,
T11815 33806-33811 JJ denotes upper
T11816 33812-33817 NN denotes panel
T11817 33817-33818 -RRB- denotes )
T11818 33820-33822 IN denotes In
T11819 33823-33831 NN denotes contrast
T11820 33831-33832 -COMMA- denotes ,
T11821 33833-33835 DT denotes no
T11822 33836-33839 NN denotes PCR
T11823 33840-33846 NN denotes signal
T11824 33847-33850 VB denotes was
T11825 33851-33859 VB denotes received
T11826 33860-33864 IN denotes with
T11827 33865-33866 DT denotes a
T11828 33867-33873 NN denotes primer
T11829 33874-33878 NN denotes pair
T11830 33879-33890 VB denotes recognizing
T11831 33891-33892 DT denotes a
T11832 33893-33899 NN denotes region
T11833 33900-33902 IN denotes in
T11834 33903-33906 DT denotes the
T11835 33907-33910 NN denotes A3G
T11836 33911-33915 NN denotes gene
T11837 33916-33924 NN denotes ∼4000 bp
T11838 33925-33935 JJ denotes downstream
T11839 33936-33938 IN denotes of
T11840 33939-33942 DT denotes the
T11841 33943-33958 NN denotes Sp1/Sp3–binding
T11842 33959-33963 NN denotes site
T11843 33964-33965 -LRB- denotes (
T11844 33965-33971 NN denotes Figure
T11845 33972-33974 NN denotes 6C
T11846 33974-33975 -COMMA- denotes ,
T11847 33976-33981 JJ denotes lower
T11848 33982-33987 NN denotes panel
T11849 33987-33988 -RRB- denotes )
T11850 33990-33994 RB denotes Only
T11851 33995-33998 DT denotes the
T11852 33999-34007 JJ denotes positive
T11853 34008-34016 NN denotes controls
T11854 34017-34023 VB denotes showed
T11855 34024-34025 DT denotes a
T11856 34026-34029 NN denotes DNA
T11857 34030-34034 NN denotes band
T11858 34034-34035 -COMMA- denotes ,
T11859 34036-34040 IN denotes with
T11860 34041-34043 DT denotes an
T11861 34044-34047 NN denotes A3G
T11862 34048-34058 NN denotes expression
T11863 34059-34066 NN denotes plasmid
T11864 34067-34069 CC denotes or
T11865 34070-34073 DT denotes the
T11866 34074-34081 JJ denotes sheared
T11867 34082-34085 CC denotes and
T11868 34086-34098 JJ denotes cross-linked
T11869 34099-34104 NN denotes input
T11870 34105-34108 NN denotes DNA
T11871 34109-34113 VB denotes used
T11872 34114-34116 IN denotes as
T11873 34117-34125 NN denotes template
T11874 34127-34131 DT denotes This
T11875 34132-34144 VB denotes demonstrates
T11876 34145-34148 DT denotes the
T11877 34149-34156 NN denotes binding
T11878 34157-34159 IN denotes of
T11879 34160-34163 NN denotes Sp1
T11880 34164-34167 CC denotes and
T11881 34168-34171 NN denotes Sp3
T11882 34172-34185 NN denotes transcription
T11883 34186-34193 NN denotes factors
T11884 34194-34196 TO denotes to
T11885 34197-34200 DT denotes the
T11886 34201-34211 JJ denotes endogenous
T11887 34212-34215 NN denotes A3G
T11888 34216-34224 NN denotes promoter
T12901 34227-34236 NN denotes Silencing
T12902 34237-34239 IN denotes of
T12903 34240-34243 NN denotes Sp1
T12904 34244-34247 CC denotes and
T12905 34248-34251 NN denotes Sp3
T12906 34252-34259 VB denotes reduces
T12907 34260-34263 NN denotes A3G
T12908 34264-34272 NN denotes promoter
T12909 34273-34281 NN denotes activity
T12910 34282-34284 TO denotes To
T12911 34285-34292 VB denotes confirm
T12912 34293-34296 DT denotes the
T12913 34297-34301 NN denotes role
T12914 34302-34304 IN denotes of
T12915 34305-34308 NN denotes Sp1
T12916 34309-34312 CC denotes and
T12917 34313-34316 NN denotes Sp3
T12918 34317-34319 IN denotes in
T12919 34320-34330 NN denotes regulation
T12920 34331-34333 IN denotes of
T12921 34334-34337 NN denotes A3G
T12922 34338-34346 NN denotes promoter
T12923 34347-34355 NN denotes activity
T12924 34355-34356 -COMMA- denotes ,
T12925 34357-34359 PRP denotes we
T12926 34360-34368 VB denotes silenced
T12927 34369-34374 PRP-DOLLAR- denotes their
T12928 34375-34386 NN denotes translation
T12929 34387-34390 IN denotes via
T12930 34391-34394 NN denotes RNA
T12931 34395-34407 NN denotes interference
T12932 34409-34422 NN denotes Functionality
T12933 34423-34425 IN denotes of
T12934 34426-34429 DT denotes the
T12935 34430-34436 NN denotes siRNAs
T12936 34437-34445 VB denotes directed
T12937 34446-34453 IN denotes against
T12938 34454-34457 NN denotes Sp1
T12939 34458-34460 CC denotes or
T12940 34461-34464 NN denotes Sp3
T12941 34465-34468 VB denotes was
T12942 34469-34478 VB denotes confirmed
T12943 34479-34481 IN denotes by
T12944 34482-34489 JJ denotes western
T12945 34490-34494 NN denotes blot
T12946 34495-34503 NN denotes analysis
T12947 34503-34504 -COLON- denotes :
T12948 34505-34512 NN denotes protein
T12949 34513-34519 NN denotes levels
T12950 34520-34522 IN denotes of
T12951 34523-34526 NN denotes Sp1
T12952 34527-34529 RB denotes as
T12953 34530-34534 RB denotes well
T12954 34535-34537 IN denotes as
T12955 34538-34541 DT denotes the
T12956 34542-34546 JJ denotes long
T12957 34547-34550 CC denotes and
T12958 34551-34556 JJ denotes short
T12959 34557-34565 NN denotes isoforms
T12960 34566-34568 IN denotes of
T12961 34569-34572 NN denotes Sp3
T12962 34573-34577 VB denotes were
T12963 34578-34586 RB denotes strongly
T12964 34587-34594 VB denotes reduced
T12965 34595-34597 IN denotes in
T12966 34598-34601 DT denotes the
T12967 34602-34610 NN denotes presence
T12968 34611-34613 IN denotes of
T12969 34614-34617 CD denotes 150
T12970 34618-34620 CC denotes or
T12971 34621-34627 CD denotes 300 ng
T12972 34628-34636 JJ denotes specific
T12973 34637-34642 NN denotes siRNA
T12974 34643-34644 -LRB- denotes (
T12975 34644-34650 NN denotes Figure
T12976 34651-34653 NN denotes 7A
T12977 34653-34654 -RRB- denotes )
T12978 34656-34658 DT denotes An
T12979 34659-34669 JJ denotes unspecific
T12980 34670-34677 NN denotes control
T12981 34678-34683 NN denotes siRNA
T12982 34684-34687 VB denotes had
T12983 34688-34690 DT denotes no
T12984 34691-34700 NN denotes influence
T12985 34701-34702 -LRB- denotes (
T12986 34702-34708 NN denotes Figure
T12987 34709-34711 NN denotes 7A
T12988 34711-34712 -RRB- denotes )
T12989 34714-34716 PRP denotes We
T12990 34717-34721 RB denotes then
T12991 34722-34735 VB denotes cotransfected
T12992 34736-34739 DT denotes the
T12993 34740-34750 NN denotes luciferase
T12994 34751-34759 NN denotes reporter
T12995 34760-34767 NN denotes plasmid
T12996 34768-34778 VB denotes containing
T12997 34779-34782 DT denotes the
T12998 34783-34789 NN denotes 180 bp
T12999 34790-34793 NN denotes A3G
T13000 34794-34802 NN denotes promoter
T13001 34803-34811 RB denotes together
T13002 34812-34816 IN denotes with
T13003 34817-34823 NN denotes 100 ng
T13004 34824-34829 NN denotes siRNA
T13005 34830-34835 VB denotes using
T13006 34836-34838 DT denotes an
T13007 34839-34848 VB denotes optimized
T13008 34849-34857 NN denotes protocol
T13009 34858-34861 IN denotes for
T13010 34862-34865 DT denotes the
T13011 34866-34880 NN denotes cotransfection
T13012 34881-34883 IN denotes of
T13013 34884-34891 NN denotes plasmid
T13014 34892-34896 CC denotes plus
T13015 34897-34902 NN denotes siRNA
T13016 34904-34908 DT denotes This
T13017 34909-34917 VB denotes resulted
T13018 34918-34920 IN denotes in
T13019 34921-34922 DT denotes a
T13020 34923-34928 CD denotes 31–43
T13021 34928-34929 NN denotes %
T13022 34930-34939 NN denotes reduction
T13023 34940-34942 IN denotes of
T13024 34943-34953 NN denotes luciferase
T13025 34954-34962 NN denotes activity
T13026 34963-34965 IN denotes in
T13027 34966-34969 DT denotes the
T13028 34970-34978 NN denotes presence
T13029 34979-34981 IN denotes of
T13030 34982-34986 NN denotes Sp1-
T13031 34987-34989 CC denotes or
T13032 34990-35002 JJ denotes Sp3-specific
T13033 35003-35008 NN denotes siRNA
T13034 35009-35017 VB denotes compared
T13035 35018-35020 TO denotes to
T13036 35021-35024 DT denotes the
T13037 35025-35032 NN denotes control
T13038 35033-35038 NN denotes siRNA
T13039 35040-35042 IN denotes In
T13040 35043-35051 NN denotes contrast
T13041 35051-35052 -COMMA- denotes ,
T13042 35053-35055 DT denotes no
T13043 35056-35065 NN denotes influence
T13044 35066-35068 IN denotes on
T13045 35069-35084 JJ denotes transcriptional
T13046 35085-35093 NN denotes activity
T13047 35094-35096 IN denotes of
T13048 35097-35100 DT denotes the
T13049 35101-35107 NN denotes 150 bp
T13050 35108-35116 NN denotes fragment
T13051 35116-35117 -COMMA- denotes ,
T13052 35118-35123 WDT denotes which
T13053 35124-35128 VB denotes does
T13054 35129-35132 RB denotes not
T13055 35133-35140 VB denotes contain
T13056 35141-35144 DT denotes the
T13057 35145-35160 JJ denotes Sp1/Sp3-binding
T13058 35161-35166 NN denotes motif
T13059 35166-35167 -COMMA- denotes ,
T13060 35168-35171 VB denotes was
T13061 35172-35180 VB denotes observed
T13062 35182-35186 RB denotes Thus
T13063 35186-35187 -COMMA- denotes ,
T13064 35188-35192 CC denotes both
T13065 35193-35196 NN denotes Sp1
T13066 35197-35200 CC denotes and
T13067 35201-35204 NN denotes Sp3
T13068 35205-35212 NN denotes factors
T13069 35213-35216 VB denotes are
T13070 35217-35226 VB denotes mediating
T13071 35227-35242 JJ denotes transcriptional
T13072 35243-35251 NN denotes activity
T13073 35252-35254 IN denotes of
T13074 35255-35258 DT denotes the
T13075 35259-35262 NN denotes A3G
T13076 35263-35271 NN denotes promoter
T21467 35283-35292 NN denotes Silencing
T21468 35293-35295 IN denotes of
T21469 35296-35299 NN denotes Sp1
T21470 35300-35303 CC denotes and
T21471 35304-35307 NN denotes Sp3
T21472 35308-35315 VB denotes reduces
T21473 35316-35319 NN denotes A3G
T21474 35320-35328 NN denotes promoter
T21475 35329-35338 NN denotes activity.
T21476 35339-35340 -LRB- denotes (
T21477 35340-35341 NN denotes A
T21478 35341-35342 -RRB- denotes )
T21479 35343-35347 NN denotes HeLa
T21480 35348-35353 NN denotes cells
T21481 35354-35358 VB denotes were
T21482 35359-35370 VB denotes transfected
T21483 35371-35375 IN denotes with
T21484 35376-35379 CD denotes 150
T21485 35380-35383 CC denotes and
T21486 35384-35390 CD denotes 300 ng
T21487 35391-35393 IN denotes of
T21488 35394-35404 JJ denotes unspecific
T21489 35404-35405 -COMMA- denotes ,
T21490 35406-35418 JJ denotes Sp1-specific
T21491 35419-35421 CC denotes or
T21492 35422-35434 JJ denotes Sp3-specific
T21493 35435-35440 NN denotes siRNA
T21494 35442-35447 IN denotes After
T21495 35448-35452 NN denotes 48 h
T21496 35452-35453 -COMMA- denotes ,
T21497 35454-35459 NN denotes cells
T21498 35460-35464 VB denotes were
T21499 35465-35474 VB denotes harvested
T21500 35475-35478 CC denotes and
T21501 35479-35482 NN denotes Sp1
T21502 35483-35486 CC denotes and
T21503 35487-35490 NN denotes Sp3
T21504 35491-35499 NN denotes proteins
T21505 35500-35504 VB denotes were
T21506 35505-35513 VB denotes detected
T21507 35514-35516 IN denotes by
T21508 35517-35524 JJ denotes western
T21509 35525-35529 NN denotes blot
T21510 35530-35538 NN denotes analysis
T21511 35540-35542 IN denotes As
T21512 35543-35550 VB denotes loading
T21513 35551-35558 NN denotes control
T21514 35558-35559 -COMMA- denotes ,
T21515 35560-35567 NN denotes protein
T21516 35568-35574 NN denotes levels
T21517 35575-35577 IN denotes of
T21518 35578-35585 NN denotes tubulin
T21519 35586-35589 VB denotes are
T21520 35590-35596 NN denotes shown.
T21521 35597-35598 -LRB- denotes (
T21522 35598-35599 NN denotes B
T21523 35599-35600 -RRB- denotes )
T21524 35601-35605 NN denotes HeLa
T21525 35606-35611 NN denotes cells
T21526 35612-35616 VB denotes were
T21527 35617-35630 VB denotes cotransfected
T21528 35631-35635 IN denotes with
T21529 35636-35644 NN denotes reporter
T21530 35645-35652 NN denotes plasmid
T21531 35653-35663 JJ denotes pGL3-Basic
T21532 35664-35674 VB denotes containing
T21533 35675-35678 CD denotes 180
T21534 35679-35681 CC denotes or
T21535 35682-35688 NN denotes 150 bp
T21536 35689-35691 IN denotes of
T21537 35692-35695 DT denotes the
T21538 35696-35699 NN denotes A3G
T21539 35700-35708 NN denotes promoter
T21540 35709-35712 CC denotes and
T21541 35713-35718 NN denotes siRNA
T21542 35720-35727 VB denotes Hundred
T21543 35728-35736 NN denotes nanogram
T21544 35737-35739 IN denotes of
T21545 35740-35750 JJ denotes unspecific
T21546 35751-35756 NN denotes siRNA
T21547 35757-35758 -LRB- denotes (
T21548 35758-35765 NN denotes control
T21549 35765-35766 -RRB- denotes )
T21550 35766-35767 -COMMA- denotes ,
T21551 35768-35780 JJ denotes Sp1-specific
T21552 35781-35786 NN denotes siRNA
T21553 35787-35788 -LRB- denotes (
T21554 35788-35791 NN denotes Sp1
T21555 35791-35792 -RRB- denotes )
T21556 35792-35793 -COMMA- denotes ,
T21557 35794-35806 JJ denotes Sp3-specific
T21558 35807-35812 NN denotes siRNA
T21559 35813-35814 -LRB- denotes (
T21560 35814-35817 NN denotes Sp3
T21561 35817-35818 -RRB- denotes )
T21562 35819-35821 CC denotes or
T21563 35822-35823 DT denotes a
T21564 35824-35831 NN denotes mixture
T21565 35832-35834 IN denotes of
T21566 35835-35840 CD denotes 50 ng
T21567 35841-35853 JJ denotes Sp1-specific
T21568 35854-35858 CC denotes plus
T21569 35859-35864 CD denotes 50 ng
T21570 35865-35877 JJ denotes Sp3-specific
T21571 35878-35883 NN denotes siRNA
T21572 35884-35885 -LRB- denotes (
T21573 35885-35892 NN denotes Sp1+Sp3
T21574 35892-35893 -RRB- denotes )
T21575 35894-35898 VB denotes were
T21576 35899-35903 VB denotes used
T21577 35905-35912 JJ denotes Firefly
T21578 35913-35923 NN denotes luciferase
T21579 35924-35934 NN denotes activities
T21580 35935-35940 IN denotes after
T21581 35941-35945 NN denotes 48 h
T21582 35946-35950 VB denotes were
T21583 35951-35961 VB denotes normalized
T21584 35962-35964 TO denotes to
T21585 35965-35976 VB denotes coexpressed
T21586 35977-35984 NN denotes renilla
T21587 35985-35995 NN denotes luciferase
T21588 35996-36006 NN denotes activities
T21589 36008-36012 NN denotes Mean
T21590 36013-36019 NN denotes values
T21591 36020-36021 -LRB- denotes (
T21592 36021-36024 NN denotes ±SD
T21593 36024-36025 -RRB- denotes )
T21594 36026-36028 IN denotes of
T21595 36029-36030 DT denotes a
T21596 36031-36045 JJ denotes representative
T21597 36046-36056 NN denotes experiment
T21598 36057-36066 VB denotes performed
T21599 36067-36069 IN denotes in
T21600 36070-36080 NN denotes triplicate
T21601 36081-36084 VB denotes are
T21602 36085-36090 VB denotes shown
T14080 36104-36111 RB denotes Shortly
T14081 36112-36117 IN denotes after
T14082 36118-36121 DT denotes the
T14083 36122-36131 NN denotes discovery
T14084 36132-36134 IN denotes of
T14085 36135-36143 NN denotes APOBEC3G
T14086 36143-36144 -COMMA- denotes ,
T14087 36145-36147 PRP denotes it
T14088 36148-36154 VB denotes became
T14089 36155-36160 JJ denotes clear
T14090 36161-36165 IN denotes that
T14091 36166-36170 DT denotes this
T14092 36171-36176 JJ denotes human
T14093 36177-36181 NN denotes gene
T14094 36182-36187 VB denotes plays
T14095 36188-36190 DT denotes an
T14096 36191-36200 JJ denotes important
T14097 36201-36205 NN denotes role
T14098 36206-36208 IN denotes in
T14099 36209-36223 JJ denotes antiretroviral
T14100 36224-36231 NN denotes defense
T14101 36232-36233 -LRB- denotes (
T14102 36233-36234 CD denotes 4
T14103 36234-36235 -RRB- denotes )
T14104 36237-36247 RB denotes Originally
T14105 36248-36258 VB denotes identified
T14106 36259-36261 IN denotes as
T14107 36262-36263 DT denotes a
T14108 36264-36275 NN denotes restriction
T14109 36276-36282 NN denotes factor
T14110 36283-36285 IN denotes of
T14111 36286-36291 NN denotes HIV-1
T14112 36292-36301 NN denotes infection
T14113 36301-36302 -COMMA- denotes ,
T14114 36303-36313 NN denotes expression
T14115 36314-36316 IN denotes of
T14116 36317-36325 NN denotes APOBEC3G
T14117 36326-36329 VB denotes was
T14118 36330-36335 VB denotes found
T14119 36336-36338 IN denotes in
T14120 36339-36344 JJ denotes human
T14121 36345-36355 JJ denotes peripheral
T14122 36356-36361 NN denotes blood
T14123 36362-36373 NN denotes lymphocytes
T14124 36374-36377 CC denotes and
T14125 36378-36389 NN denotes macrophages
T14126 36389-36390 -COMMA- denotes ,
T14127 36391-36396 WDT denotes which
T14128 36397-36406 VB denotes represent
T14129 36407-36410 DT denotes the
T14130 36411-36415 JJ denotes main
T14131 36416-36422 NN denotes target
T14132 36423-36428 NN denotes cells
T14133 36429-36432 IN denotes for
T14134 36433-36438 NN denotes HIV-1
T14135 36439-36440 -LRB- denotes (
T14136 36440-36442 CD denotes 32
T14137 36442-36443 -RRB- denotes )
T14138 36445-36447 IN denotes In
T14139 36448-36456 NN denotes addition
T14140 36456-36457 -COMMA- denotes ,
T14141 36458-36461 DT denotes the
T14142 36462-36469 NN denotes protein
T14143 36470-36473 VB denotes was
T14144 36474-36482 VB denotes detected
T14145 36483-36485 IN denotes in
T14146 36486-36490 NN denotes lung
T14147 36490-36491 -COMMA- denotes ,
T14148 36492-36497 NN denotes liver
T14149 36497-36498 -COMMA- denotes ,
T14150 36499-36505 NN denotes spleen
T14151 36505-36506 -COMMA- denotes ,
T14152 36507-36513 NN denotes testis
T14153 36514-36517 CC denotes and
T14154 36518-36523 NN denotes ovary
T14155 36523-36524 -COMMA- denotes ,
T14156 36525-36528 CC denotes but
T14157 36529-36535 JJ denotes little
T14158 36536-36538 VB denotes is
T14159 36539-36544 VB denotes known
T14160 36545-36550 IN denotes about
T14161 36551-36554 PRP-DOLLAR- denotes its
T14162 36555-36570 JJ denotes transcriptional
T14163 36571-36581 NN denotes regulation
T14164 36582-36583 -LRB- denotes (
T14165 36583-36591 CD denotes 29,32,47
T14166 36591-36592 -RRB- denotes )
T14167 36594-36596 TO denotes To
T14168 36597-36604 VB denotes address
T14169 36605-36609 DT denotes this
T14170 36610-36618 NN denotes question
T14171 36618-36619 -COMMA- denotes ,
T14172 36620-36622 PRP denotes we
T14173 36623-36629 VB denotes cloned
T14174 36630-36633 DT denotes the
T14175 36634-36639 JJ denotes human
T14176 36640-36648 NN denotes APOBEC3G
T14177 36649-36657 NN denotes promoter
T14178 36658-36661 CC denotes and
T14179 36662-36670 VB denotes analyzed
T14180 36671-36674 PRP-DOLLAR- denotes its
T14181 36675-36685 NN denotes regulation
T14182 36686-36688 IN denotes in
T14183 36689-36690 NN denotes T
T14184 36691-36696 NN denotes cells
T14185 36698-36706 VB denotes Applying
T14186 36707-36714 NN denotes 5′-RACE
T14187 36714-36715 -COMMA- denotes ,
T14188 36716-36718 PRP denotes we
T14189 36719-36729 VB denotes identified
T14190 36730-36738 JJ denotes multiple
T14191 36739-36744 NN denotes start
T14192 36745-36750 NN denotes sites
T14193 36751-36754 IN denotes for
T14194 36755-36768 NN denotes transcription
T14195 36769-36771 IN denotes of
T14196 36772-36775 DT denotes the
T14197 36776-36779 NN denotes A3G
T14198 36780-36784 NN denotes gene
T14199 36786-36790 DT denotes This
T14200 36791-36802 NN denotes observation
T14201 36803-36805 VB denotes is
T14202 36806-36816 JJ denotes consistent
T14203 36817-36821 IN denotes with
T14204 36822-36825 DT denotes the
T14205 36826-36830 NN denotes fact
T14206 36831-36835 IN denotes that
T14207 36836-36839 DT denotes the
T14208 36840-36844 NN denotes gene
T14209 36845-36852 VB denotes appears
T14210 36853-36855 TO denotes to
T14211 36856-36860 VB denotes lack
T14212 36861-36870 JJ denotes canonical
T14213 36871-36876 NN denotes CCAAT
T14214 36877-36880 CC denotes and
T14215 36881-36885 NN denotes TATA
T14216 36886-36891 NN denotes boxes
T14217 36892-36893 -LRB- denotes (
T14218 36893-36895 CD denotes 32
T14219 36895-36896 -RRB- denotes )
T14220 36896-36897 -COMMA- denotes ,
T14221 36898-36899 DT denotes a
T14222 36900-36909 NN denotes condition
T14223 36910-36915 RB denotes often
T14224 36916-36926 VB denotes associated
T14225 36927-36931 IN denotes with
T14226 36932-36940 JJ denotes multiple
T14227 36941-36956 JJ denotes transcriptional
T14228 36957-36962 NN denotes start
T14229 36963-36968 NN denotes sites
T14230 36969-36970 -LRB- denotes (
T14231 36970-36975 CD denotes 49–51
T14232 36975-36976 -RRB- denotes )
T14233 36978-36985 RB denotes However
T14234 36985-36986 -COMMA- denotes ,
T14235 36987-36990 CD denotes one
T14236 36991-36997 JJ denotes single
T14237 36998-37003 NN denotes start
T14238 37004-37008 NN denotes site
T14239 37009-37012 VB denotes was
T14240 37013-37021 VB denotes detected
T14241 37022-37024 IN denotes in
T14242 37025-37026 CD denotes 6
T14243 37027-37029 IN denotes of
T14244 37030-37032 CD denotes 19
T14245 37033-37039 NN denotes clones
T14246 37040-37043 CC denotes and
T14247 37044-37047 VB denotes was
T14248 37048-37058 VB denotes designated
T14249 37059-37061 IN denotes as
T14250 37062-37064 CD denotes +1
T14251 37066-37070 DT denotes This
T14252 37071-37074 NN denotes TSS
T14253 37075-37077 VB denotes is
T14254 37078-37085 JJ denotes located
T14255 37086-37091 RB denotes 66 bp
T14256 37092-37100 RB denotes upstream
T14257 37101-37103 IN denotes of
T14258 37104-37107 DT denotes the
T14259 37108-37113 NN denotes start
T14260 37114-37116 IN denotes of
T14261 37117-37120 DT denotes the
T14262 37121-37130 VB denotes published
T14263 37131-37135 NN denotes mRNA
T14264 37136-37144 NN denotes sequence
T14265 37145-37146 -LRB- denotes (
T14266 37146-37154 NN denotes GenBank™
T14267 37155-37163 NN denotes NM021822
T14268 37163-37164 -RRB- denotes )
T14269 37166-37168 PRP denotes We
T14270 37169-37175 VB denotes cloned
T14271 37176-37177 DT denotes a
T14272 37178-37185 NN denotes 1025 bp
T14273 37186-37194 NN denotes promoter
T14274 37194-37195 -COMMA- denotes ,
T14275 37196-37201 WDT denotes which
T14276 37202-37208 VB denotes ranges
T14277 37209-37213 IN denotes from
T14278 37214-37222 NN denotes position
T14279 37223-37231 CD denotes −959/+66
T14280 37232-37240 JJ denotes relative
T14281 37241-37243 TO denotes to
T14282 37244-37247 DT denotes the
T14283 37248-37258 VB denotes identified
T14284 37259-37262 NN denotes TSS
T14285 37264-37274 NN denotes Luciferase
T14286 37275-37283 NN denotes reporter
T14287 37284-37290 NN denotes assays
T14288 37291-37297 VB denotes showed
T14289 37298-37302 IN denotes that
T14290 37303-37307 DT denotes this
T14291 37308-37316 NN denotes promoter
T14292 37317-37320 VB denotes was
T14293 37321-37338 RB denotes transcriptionally
T14294 37339-37345 JJ denotes active
T14295 37346-37348 IN denotes in
T14296 37349-37356 NN denotes A3.01 T
T14297 37357-37362 NN denotes cells
T14298 37364-37373 NN denotes Treatment
T14299 37374-37378 IN denotes with
T14300 37379-37382 DT denotes the
T14301 37383-37390 NN denotes phorbol
T14302 37391-37396 NN denotes ester
T14303 37397-37400 NN denotes TPA
T14304 37401-37404 VB denotes did
T14305 37405-37408 RB denotes not
T14306 37409-37416 RB denotes further
T14307 37417-37424 VB denotes enhance
T14308 37425-37440 JJ denotes transcriptional
T14309 37441-37449 NN denotes activity
T14310 37449-37450 -COMMA- denotes ,
T14311 37451-37459 IN denotes although
T14312 37460-37472 NN denotes upregulation
T14313 37473-37475 IN denotes of
T14314 37476-37479 NN denotes A3G
T14315 37480-37484 NN denotes mRNA
T14316 37485-37491 NN denotes levels
T14317 37492-37494 IN denotes in
T14318 37495-37496 NN denotes T
T14319 37497-37502 NN denotes cells
T14320 37503-37505 IN denotes by
T14321 37506-37509 NN denotes TPA
T14322 37510-37513 VB denotes has
T14323 37514-37518 VB denotes been
T14324 37519-37528 VB denotes described
T14325 37529-37530 -LRB- denotes (
T14326 37530-37532 CD denotes 33
T14327 37532-37533 -RRB- denotes )
T14328 37535-37539 NNP denotes Rose
T14329 37540-37542 FW denotes et
T14330 37543-37546 FW denotes al.
T14331 37547-37551 VB denotes used
T14332 37552-37563 NN denotes actinomycin
T14333 37564-37565 NN denotes D
T14334 37566-37568 TO denotes to
T14335 37569-37574 VB denotes block
T14336 37575-37582 JJ denotes further
T14337 37583-37596 NN denotes transcription
T14338 37597-37600 CC denotes and
T14339 37601-37604 VB denotes did
T14340 37605-37608 RB denotes not
T14341 37609-37613 VB denotes find
T14342 37614-37622 NN denotes evidence
T14343 37623-37626 IN denotes for
T14344 37627-37635 VB denotes enhanced
T14345 37636-37640 NN denotes mRNA
T14346 37641-37650 NN denotes stability
T14347 37652-37661 RB denotes Therefore
T14348 37661-37662 -COMMA- denotes ,
T14349 37663-37666 DT denotes the
T14350 37667-37674 NN denotes authors
T14351 37675-37684 VB denotes suggested
T14352 37685-37689 IN denotes that
T14353 37690-37692 DT denotes an
T14354 37693-37701 VB denotes enhanced
T14355 37702-37715 NN denotes transcription
T14356 37716-37720 NN denotes rate
T14357 37721-37726 MD denotes could
T14358 37727-37729 VB denotes be
T14359 37730-37741 JJ denotes responsible
T14360 37742-37745 IN denotes for
T14361 37746-37749 DT denotes the
T14362 37750-37759 VB denotes increased
T14363 37760-37766 NN denotes amount
T14364 37767-37769 IN denotes of
T14365 37770-37773 NN denotes A3G
T14366 37774-37778 NN denotes mRNA
T14367 37779-37784 IN denotes after
T14368 37785-37788 NN denotes TPA
T14369 37789-37798 NN denotes treatment
T14370 37800-37807 RB denotes However
T14371 37807-37808 -COMMA- denotes ,
T14372 37809-37812 DT denotes the
T14373 37813-37821 NN denotes promoter
T14374 37822-37830 NN denotes analysis
T14375 37831-37833 PRP denotes we
T14376 37834-37843 VB denotes performed
T14377 37844-37853 VB denotes indicates
T14378 37854-37855 DT denotes a
T14379 37856-37865 JJ denotes different
T14380 37866-37875 NN denotes mechanism
T14381 37876-37880 WDT denotes that
T14382 37881-37883 VB denotes is
T14383 37884-37895 JJ denotes independent
T14384 37896-37898 IN denotes of
T14385 37899-37914 JJ denotes transcriptional
T14386 37915-37925 NN denotes regulation
T14387 37927-37929 IN denotes In
T14388 37930-37938 NN denotes addition
T14389 37938-37939 -COMMA- denotes ,
T14390 37940-37942 PRP denotes we
T14391 37943-37951 VB denotes observed
T14392 37952-37956 IN denotes that
T14393 37957-37960 DT denotes the
T14394 37961-37964 NN denotes A3G
T14395 37965-37973 NN denotes promoter
T14396 37974-37977 VB denotes was
T14397 37978-37981 RB denotes not
T14398 37982-37991 JJ denotes inducible
T14399 37992-37994 IN denotes by
T14400 37995-38000 NN denotes IFN-α
T14401 38001-38003 CC denotes or
T14402 38004-38009 NN denotes IFN-γ
T14403 38010-38012 IN denotes in
T14404 38013-38020 NN denotes A3.01 T
T14405 38021-38026 NN denotes cells
T14406 38026-38027 -COMMA- denotes ,
T14407 38028-38035 IN denotes whereas
T14408 38036-38038 IN denotes in
T14409 38039-38042 DT denotes the
T14410 38043-38050 JJ denotes hepatic
T14411 38051-38055 NN denotes cell
T14412 38056-38060 NN denotes line
T14413 38061-38066 NN denotes HepG2
T14414 38066-38067 -COMMA- denotes ,
T14415 38068-38069 DT denotes a
T14416 38070-38078 JJ denotes moderate
T14417 38079-38088 NN denotes induction
T14418 38089-38092 VB denotes was
T14419 38093-38101 VB denotes measured
T14420 38103-38105 PRP denotes It
T14421 38106-38109 VB denotes has
T14422 38110-38114 VB denotes been
T14423 38115-38124 VB denotes described
T14424 38125-38135 RB denotes previously
T14425 38136-38140 IN denotes that
T14426 38141-38144 NN denotes A3G
T14427 38145-38149 NN denotes gene
T14428 38150-38160 NN denotes expression
T14429 38161-38163 VB denotes is
T14430 38164-38175 VB denotes upregulated
T14431 38176-38178 IN denotes by
T14432 38179-38190 NN denotes interferons
T14433 38191-38193 IN denotes in
T14434 38194-38205 NN denotes hepatocytes
T14435 38206-38209 CC denotes and
T14436 38210-38221 NN denotes macrophages
T14437 38222-38223 -LRB- denotes (
T14438 38223-38228 CD denotes 46–48
T14439 38228-38229 -COMMA- denotes ,
T14440 38230-38232 CD denotes 52
T14441 38232-38233 -RRB- denotes )
T14442 38235-38237 IN denotes In
T14443 38238-38242 DT denotes this
T14444 38243-38250 NN denotes context
T14445 38250-38251 -COMMA- denotes ,
T14446 38252-38255 CD denotes two
T14447 38256-38277 JJ denotes interferon-responsive
T14448 38278-38286 NN denotes elements
T14449 38287-38291 VB denotes have
T14450 38292-38296 VB denotes been
T14451 38297-38307 VB denotes identified
T14452 38308-38310 IN denotes at
T14453 38311-38314 DT denotes the
T14454 38315-38324 NN denotes positions
T14455 38325-38330 CD denotes −6/+9
T14456 38331-38334 CC denotes and
T14457 38335-38341 CD denotes +1/+15
T14458 38342-38350 JJ denotes relative
T14459 38351-38353 TO denotes to
T14460 38354-38357 DT denotes the
T14461 38358-38361 NN denotes TSS
T14462 38362-38363 -LRB- denotes (
T14463 38363-38365 CD denotes 48
T14464 38365-38366 -RRB- denotes )
T14465 38368-38378 JJ denotes Consistent
T14466 38379-38383 IN denotes with
T14467 38384-38388 DT denotes this
T14468 38389-38393 NN denotes data
T14469 38393-38394 -COMMA- denotes ,
T14470 38395-38397 PRP denotes we
T14471 38398-38406 VB denotes observed
T14472 38407-38409 DT denotes an
T14473 38410-38420 NN denotes interferon
T14474 38421-38430 NN denotes induction
T14475 38431-38433 IN denotes in
T14476 38434-38445 NN denotes hepatocytes
T14477 38446-38449 IN denotes for
T14478 38450-38453 DT denotes the
T14479 38454-38463 NN denotes fragments
T14480 38464-38471 VB denotes ranging
T14481 38472-38479 IN denotes between
T14482 38480-38484 CD denotes 1025
T14483 38485-38488 CC denotes and
T14484 38489-38495 NN denotes 120 bp
T14485 38496-38502 NN denotes length
T14486 38504-38507 DT denotes The
T14487 38508-38516 NN denotes activity
T14488 38517-38519 IN denotes of
T14489 38520-38523 DT denotes the
T14490 38524-38529 NN denotes 60 bp
T14491 38530-38538 NN denotes fragment
T14492 38539-38543 WDT denotes that
T14493 38544-38548 VB denotes does
T14494 38549-38552 RB denotes not
T14495 38553-38560 VB denotes contain
T14496 38561-38566 DT denotes these
T14497 38567-38573 NN denotes motifs
T14498 38574-38577 VB denotes was
T14499 38578-38581 RB denotes not
T14500 38582-38590 VB denotes affected
T14501 38592-38596 RB denotes Thus
T14502 38596-38597 -COMMA- denotes ,
T14503 38598-38601 DT denotes the
T14504 38602-38611 NN denotes induction
T14505 38612-38614 PRP denotes we
T14506 38615-38623 VB denotes observed
T14507 38624-38627 VB denotes was
T14508 38628-38632 RB denotes most
T14509 38633-38639 RB denotes likely
T14510 38640-38648 VB denotes mediated
T14511 38649-38651 IN denotes by
T14512 38652-38655 DT denotes the
T14513 38656-38665 VB denotes described
T14514 38666-38687 JJ denotes interferon-responsive
T14515 38688-38696 NN denotes elements
T14516 38698-38705 RB denotes However
T14517 38705-38706 -COMMA- denotes ,
T14518 38707-38716 VB denotes according
T14519 38717-38719 TO denotes to
T14520 38720-38723 PRP-DOLLAR- denotes our
T14521 38724-38731 NN denotes results
T14522 38731-38732 -COMMA- denotes ,
T14523 38733-38738 DT denotes these
T14524 38739-38745 NN denotes motifs
T14525 38746-38749 MD denotes can
T14526 38750-38757 VB denotes enhance
T14527 38758-38771 NN denotes transcription
T14528 38772-38774 IN denotes in
T14529 38775-38782 JJ denotes hepatic
T14530 38783-38788 NN denotes cells
T14531 38788-38789 -COMMA- denotes ,
T14532 38790-38793 CC denotes but
T14533 38794-38797 RB denotes not
T14534 38798-38800 IN denotes in
T14535 38801-38802 NN denotes T
T14536 38803-38808 NN denotes cells
T14537 38810-38814 DT denotes This
T14538 38815-38817 VB denotes is
T14539 38818-38828 JJ denotes surprising
T14540 38828-38829 -COMMA- denotes ,
T14541 38830-38835 IN denotes since
T14542 38836-38851 JJ denotes IFN-α-inducible
T14543 38852-38861 NN denotes signaling
T14544 38862-38870 NN denotes cascades
T14545 38871-38874 VB denotes are
T14546 38875-38882 JJ denotes present
T14547 38883-38885 IN denotes in
T14548 38886-38893 NN denotes A3.01 T
T14549 38894-38899 NN denotes cells
T14550 38899-38900 -COLON- denotes :
T14551 38901-38903 PRP denotes we
T14552 38904-38910 VB denotes showed
T14553 38911-38915 IN denotes that
T14554 38916-38919 DT denotes the
T14555 38920-38927 NN denotes control
T14556 38928-38935 NN denotes plasmid
T14557 38936-38945 VB denotes harboring
T14558 38946-38967 JJ denotes interferon-responsive
T14559 38968-38971 NN denotes GAS
T14560 38972-38980 NN denotes elements
T14561 38981-38984 VB denotes was
T14562 38985-38993 RB denotes markedly
T14563 38994-39001 VB denotes induced
T14564 39002-39004 IN denotes by
T14565 39005-39010 NN denotes IFN-α
T14566 39011-39020 NN denotes treatment
T14567 39022-39024 IN denotes In
T14568 39025-39033 NN denotes contrast
T14569 39033-39034 -COMMA- denotes ,
T14570 39035-39038 DT denotes the
T14571 39039-39042 NN denotes GAS
T14572 39043-39050 NN denotes element
T14573 39051-39054 VB denotes was
T14574 39055-39058 RB denotes not
T14575 39059-39069 JJ denotes responsive
T14576 39070-39072 TO denotes to
T14577 39073-39078 NN denotes IFN-γ
T14578 39079-39088 NN denotes treatment
T14579 39089-39091 IN denotes in
T14580 39092-39097 DT denotes these
T14581 39098-39103 NN denotes cells
T14582 39103-39104 -COMMA- denotes ,
T14583 39105-39115 VB denotes suggesting
T14584 39116-39120 IN denotes that
T14585 39121-39124 PRP-DOLLAR- denotes our
T14586 39125-39126 NN denotes T
T14587 39127-39131 NN denotes cell
T14588 39132-39136 NN denotes line
T14589 39137-39140 VB denotes was
T14590 39141-39144 RB denotes not
T14591 39145-39149 JJ denotes able
T14592 39150-39152 TO denotes to
T14593 39153-39160 VB denotes mediate
T14594 39161-39174 JJ denotes IFN-γ-induced
T14595 39175-39182 NN denotes signals
T14596 39184-39186 RB denotes So
T14597 39187-39190 RB denotes far
T14598 39190-39191 -COMMA- denotes ,
T14599 39192-39200 VB denotes enhanced
T14600 39201-39204 NN denotes A3G
T14601 39205-39213 NN denotes promoter
T14602 39214-39222 NN denotes activity
T14603 39223-39225 IN denotes by
T14604 39226-39237 NN denotes interferons
T14605 39238-39240 VB denotes is
T14606 39241-39248 RB denotes clearly
T14607 39249-39258 VB denotes described
T14608 39259-39261 IN denotes in
T14609 39262-39273 NN denotes hepatocytes
T14610 39274-39277 CC denotes and
T14611 39278-39289 NN denotes macrophages
T14612 39289-39290 -COMMA- denotes ,
T14613 39291-39298 IN denotes whereas
T14614 39299-39302 DT denotes the
T14615 39303-39312 NN denotes situation
T14616 39313-39315 IN denotes in
T14617 39316-39317 NN denotes T
T14618 39318-39323 NN denotes cells
T14619 39324-39326 VB denotes is
T14620 39327-39332 RB denotes still
T14621 39333-39340 JJ denotes unclear
T14622 39342-39343 DT denotes A
T14623 39344-39350 JJ denotes recent
T14624 39351-39356 NN denotes study
T14625 39357-39362 VB denotes found
T14626 39363-39365 DT denotes no
T14627 39366-39375 NN denotes influence
T14628 39376-39378 IN denotes of
T14629 39379-39384 NN denotes IFN-α
T14630 39385-39387 CC denotes or
T14631 39388-39393 NN denotes IFN-γ
T14632 39394-39396 IN denotes on
T14633 39397-39400 NN denotes A3G
T14634 39401-39411 NN denotes expression
T14635 39412-39414 IN denotes in
T14636 39415-39422 VB denotes resting
T14637 39423-39430 JJ denotes primary
T14638 39431-39436 NN denotes blood
T14639 39437-39448 NN denotes lymphocytes
T14640 39449-39450 -LRB- denotes (
T14641 39450-39452 CD denotes 52
T14642 39452-39453 -RRB- denotes )
T14643 39455-39462 DT denotes Another
T14644 39463-39474 NN denotes publication
T14645 39475-39484 VB denotes describes
T14646 39485-39487 DT denotes an
T14647 39488-39496 VB denotes enhanced
T14648 39497-39507 NN denotes expression
T14649 39508-39510 IN denotes of
T14650 39511-39514 NN denotes A3G
T14651 39515-39520 IN denotes after
T14652 39521-39526 NN denotes IFN-α
T14653 39527-39536 NN denotes treatment
T14654 39537-39539 IN denotes in
T14655 39540-39547 VB denotes resting
T14656 39548-39555 JJ denotes primary
T14657 39556-39561 NN denotes CD4 T
T14658 39562-39567 NN denotes cells
T14659 39567-39568 -COMMA- denotes ,
T14660 39569-39572 CC denotes but
T14661 39573-39576 RB denotes not
T14662 39577-39579 IN denotes in
T14663 39580-39589 VB denotes activated
T14664 39590-39591 NN denotes T
T14665 39592-39597 NN denotes cells
T14666 39598-39599 -LRB- denotes (
T14667 39599-39601 CD denotes 53
T14668 39601-39602 -RRB- denotes )
T14669 39604-39608 DT denotes This
T14670 39609-39620 NN denotes observation
T14671 39621-39623 VB denotes is
T14672 39624-39627 RB denotes not
T14673 39628-39641 JJ denotes contradictory
T14674 39642-39644 TO denotes to
T14675 39645-39648 PRP-DOLLAR- denotes our
T14676 39649-39656 NN denotes results
T14677 39657-39662 IN denotes since
T14678 39663-39664 NN denotes T
T14679 39665-39669 NN denotes cell
T14680 39670-39675 NN denotes lines
T14681 39676-39679 VB denotes are
T14682 39680-39691 RB denotes mitotically
T14683 39692-39698 JJ denotes active
T14684 39699-39702 CC denotes and
T14685 39703-39712 RB denotes therefore
T14686 39713-39719 RB denotes rather
T14687 39720-39722 IN denotes in
T14688 39723-39725 DT denotes an
T14689 39726-39735 VB denotes activated
T14690 39736-39740 IN denotes than
T14691 39741-39743 IN denotes in
T14692 39744-39745 DT denotes a
T14693 39746-39753 JJ denotes resting
T14694 39754-39759 NN denotes state
T14695 39761-39763 IN denotes In
T14696 39764-39774 NN denotes conclusion
T14697 39774-39775 -COMMA- denotes ,
T14698 39776-39779 DT denotes the
T14699 39780-39787 JJ denotes current
T14700 39788-39792 NN denotes data
T14701 39793-39801 VB denotes suggests
T14702 39802-39806 IN denotes that
T14703 39807-39817 NN denotes regulation
T14704 39818-39820 IN denotes of
T14705 39821-39824 DT denotes the
T14706 39825-39828 NN denotes A3G
T14707 39829-39837 NN denotes promoter
T14708 39838-39846 NN denotes activity
T14709 39847-39849 IN denotes by
T14710 39850-39861 NN denotes interferons
T14711 39862-39864 VB denotes is
T14712 39865-39874 JJ denotes dependent
T14713 39875-39877 IN denotes on
T14714 39878-39881 DT denotes the
T14715 39882-39886 NN denotes cell
T14716 39887-39891 NN denotes type
T14717 39892-39895 CC denotes and
T14718 39896-39904 RB denotes possibly
T14719 39905-39909 RB denotes also
T14720 39910-39914 IN denotes from
T14721 39915-39918 DT denotes the
T14722 39919-39927 JJ denotes cellular
T14723 39928-39938 NN denotes activation
T14724 39939-39945 NN denotes status
T14725 39947-39949 PRP denotes We
T14726 39950-39962 RB denotes additionally
T14727 39963-39971 VB denotes analyzed
T14728 39972-39975 DT denotes the
T14729 39976-39985 NN denotes influence
T14730 39986-39988 IN denotes of
T14731 39989-39994 NN denotes HIV-1
T14732 39995-40003 NN denotes proteins
T14733 40004-40006 IN denotes on
T14734 40007-40010 NN denotes A3G
T14735 40011-40019 NN denotes promoter
T14736 40020-40028 NN denotes activity
T14737 40030-40033 DT denotes The
T14738 40034-40039 NN denotes HIV-1
T14739 40040-40043 NN denotes Vif
T14740 40044-40051 NN denotes protein
T14741 40052-40054 VB denotes is
T14742 40055-40067 VB denotes neutralizing
T14743 40068-40071 DT denotes the
T14744 40072-40081 JJ denotes antiviral
T14745 40082-40090 NN denotes function
T14746 40091-40093 IN denotes of
T14747 40094-40097 NN denotes A3G
T14748 40098-40100 IN denotes by
T14749 40101-40102 DT denotes a
T14750 40103-40112 NN denotes multitude
T14751 40113-40115 IN denotes of
T14752 40116-40120 NN denotes ways
T14753 40122-40131 VB denotes Targeting
T14754 40132-40135 DT denotes the
T14755 40136-40139 NN denotes A3G
T14756 40140-40147 NN denotes protein
T14757 40148-40151 IN denotes for
T14758 40152-40163 JJ denotes proteasomal
T14759 40164-40175 NN denotes degradation
T14760 40176-40178 VB denotes is
T14761 40179-40189 VB denotes considered
T14762 40190-40192 TO denotes to
T14763 40193-40195 VB denotes be
T14764 40196-40199 DT denotes the
T14765 40200-40204 JJ denotes main
T14766 40205-40209 NN denotes mode
T14767 40210-40212 IN denotes of
T14768 40213-40219 NN denotes action
T14769 40220-40221 -LRB- denotes (
T14770 40221-40226 CD denotes 37–41
T14771 40226-40227 -RRB- denotes )
T14772 40227-40228 -COMMA- denotes ,
T14773 40229-40232 CC denotes but
T14774 40233-40235 PRP denotes it
T14775 40236-40243 VB denotes becomes
T14776 40244-40248 JJ denotes more
T14777 40249-40252 CC denotes and
T14778 40253-40257 RB denotes more
T14779 40258-40263 JJ denotes clear
T14780 40264-40268 IN denotes that
T14781 40269-40274 JJ denotes other
T14782 40275-40285 NN denotes mechanisms
T14783 40286-40289 VB denotes are
T14784 40290-40294 RB denotes also
T14785 40295-40303 VB denotes involved
T14786 40305-40310 EX denotes There
T14787 40311-40313 VB denotes is
T14788 40314-40322 NN denotes evidence
T14789 40323-40327 IN denotes that
T14790 40328-40331 NNP denotes Vif
T14791 40332-40336 RB denotes also
T14792 40337-40345 VB denotes promotes
T14793 40346-40355 NN denotes exclusion
T14794 40356-40358 IN denotes of
T14795 40359-40362 NN denotes A3G
T14796 40363-40367 IN denotes from
T14797 40368-40371 DT denotes the
T14798 40372-40377 NN denotes virus
T14799 40378-40387 NN denotes particles
T14800 40388-40391 CC denotes and
T14801 40392-40394 DT denotes an
T14802 40395-40404 NN denotes influence
T14803 40405-40407 IN denotes on
T14804 40408-40411 DT denotes the
T14805 40412-40415 NN denotes A3G
T14806 40416-40427 NN denotes translation
T14807 40428-40435 NN denotes process
T14808 40436-40438 VB denotes is
T14809 40439-40448 VB denotes discussed
T14810 40449-40450 -LRB- denotes (
T14811 40450-40457 CD denotes 8,42,43
T14812 40457-40458 -RRB- denotes )
T14813 40460-40463 DT denotes The
T14814 40464-40472 NN denotes question
T14815 40473-40480 IN denotes whether
T14816 40481-40484 NN denotes Vif
T14817 40485-40491 VB denotes alters
T14818 40492-40505 NN denotes transcription
T14819 40506-40516 VB denotes controlled
T14820 40517-40519 IN denotes by
T14821 40520-40523 DT denotes the
T14822 40524-40527 NN denotes A3G
T14823 40528-40536 NN denotes promoter
T14824 40537-40540 VB denotes has
T14825 40541-40544 RB denotes not
T14826 40545-40549 VB denotes been
T14827 40550-40558 VB denotes analyzed
T14828 40559-40561 RB denotes so
T14829 40562-40565 RB denotes far
T14830 40567-40570 PRP-DOLLAR- denotes Our
T14831 40571-40579 NN denotes analysis
T14832 40580-40589 VB denotes indicates
T14833 40590-40594 IN denotes that
T14834 40595-40608 NN denotes transcription
T14835 40609-40613 IN denotes from
T14836 40614-40617 DT denotes the
T14837 40618-40621 NN denotes A3G
T14838 40622-40630 NN denotes promoter
T14839 40631-40633 VB denotes is
T14840 40634-40644 JJ denotes unaffected
T14841 40645-40647 IN denotes by
T14842 40648-40651 NN denotes Vif
T14843 40652-40654 CC denotes or
T14844 40655-40660 JJ denotes other
T14845 40661-40666 NN denotes HIV-1
T14846 40667-40675 NN denotes proteins
T14847 40677-40682 VB denotes Taken
T14848 40683-40691 RB denotes together
T14849 40691-40692 -COMMA- denotes ,
T14850 40693-40695 IN denotes in
T14851 40696-40697 NN denotes T
T14852 40698-40702 NN denotes cell
T14853 40703-40708 NN denotes lines
T14854 40708-40709 -COMMA- denotes ,
T14855 40710-40713 DT denotes the
T14856 40714-40717 NN denotes A3G
T14857 40718-40726 NN denotes promoter
T14858 40727-40734 VB denotes appears
T14859 40735-40749 RB denotes constitutively
T14860 40750-40756 JJ denotes active
T14861 40758-40760 IN denotes By
T14862 40761-40771 VB denotes generating
T14863 40772-40773 DT denotes a
T14864 40774-40780 NN denotes series
T14865 40781-40783 IN denotes of
T14866 40784-40786 CD denotes 5′
T14867 40787-40796 NN denotes deletions
T14868 40796-40797 -COMMA- denotes ,
T14869 40798-40800 PRP denotes we
T14870 40801-40807 VB denotes showed
T14871 40808-40812 IN denotes that
T14872 40813-40816 DT denotes the
T14873 40817-40821 NN denotes core
T14874 40822-40830 NN denotes promoter
T14875 40831-40833 VB denotes is
T14876 40834-40841 JJ denotes located
T14877 40842-40848 IN denotes within
T14878 40849-40852 DT denotes the
T14879 40853-40859 NN denotes region
T14880 40860-40868 CD denotes −114/+66
T14881 40869-40877 JJ denotes relative
T14882 40878-40880 TO denotes to
T14883 40881-40884 DT denotes the
T14884 40885-40888 NN denotes TSS
T14885 40890-40894 DT denotes This
T14886 40895-40901 NN denotes 180 bp
T14887 40902-40910 NN denotes promoter
T14888 40911-40914 VB denotes was
T14889 40915-40932 RB denotes transcriptionally
T14890 40933-40939 JJ denotes active
T14891 40940-40942 IN denotes in
T14892 40943-40946 DT denotes the
T14893 40947-40955 JJ denotes lymphoid
T14894 40955-40956 -COMMA- denotes ,
T14895 40957-40964 JJ denotes myeloid
T14896 40965-40968 CC denotes and
T14897 40969-40976 JJ denotes hepatic
T14898 40977-40981 NN denotes cell
T14899 40982-40987 NN denotes lines
T14900 40988-40990 PRP denotes we
T14901 40991-40997 VB denotes tested
T14902 40997-40998 -COMMA- denotes ,
T14903 40999-41009 VB denotes indicating
T14904 41010-41014 IN denotes that
T14905 41015-41025 JJ denotes ubiquitous
T14906 41026-41039 NN denotes transcription
T14907 41040-41047 NN denotes factors
T14908 41048-41051 VB denotes are
T14909 41052-41060 VB denotes involved
T14910 41061-41063 IN denotes in
T14911 41064-41074 NN denotes regulation
T14912 41075-41077 IN denotes of
T14913 41078-41081 NN denotes A3G
T14914 41082-41086 NN denotes gene
T14915 41087-41100 NN denotes transcription
T14916 41102-41103 DT denotes A
T14917 41104-41110 NN denotes GC-box
T14918 41111-41115 IN denotes with
T14919 41116-41119 DT denotes the
T14920 41120-41128 NN denotes sequence
T14921 41129-41139 NN denotes TGGGCGGGAC
T14922 41140-41143 VB denotes was
T14923 41144-41154 VB denotes identified
T14924 41155-41157 IN denotes at
T14925 41158-41166 NN denotes position
T14926 41167-41174 CD denotes −87/−78
T14927 41175-41177 IN denotes of
T14928 41178-41181 DT denotes the
T14929 41182-41185 NN denotes A3G
T14930 41186-41194 NN denotes promoter
T14931 41196-41200 DT denotes This
T14932 41201-41207 NN denotes GC-box
T14933 41208-41210 VB denotes is
T14934 41211-41220 JJ denotes essential
T14935 41221-41224 IN denotes for
T14936 41225-41230 JJ denotes basal
T14937 41231-41239 NN denotes promoter
T14938 41240-41248 NN denotes activity
T14939 41248-41249 -COMMA- denotes ,
T14940 41250-41255 IN denotes since
T14941 41256-41264 VB denotes changing
T14942 41265-41268 DT denotes the
T14943 41269-41274 NN denotes motif
T14944 41275-41277 TO denotes to
T14945 41278-41288 NN denotes TGTTCGGGAC
T14946 41289-41291 IN denotes by
T14947 41292-41303 VB denotes introducing
T14948 41304-41307 CD denotes two
T14949 41308-41313 NN denotes point
T14950 41314-41323 NN denotes mutations
T14951 41324-41332 RB denotes strongly
T14952 41333-41340 VB denotes reduced
T14953 41341-41344 NN denotes A3G
T14954 41345-41353 NN denotes promoter
T14955 41354-41362 NN denotes activity
T14956 41364-41367 DT denotes The
T14957 41368-41383 JJ denotes transcriptional
T14958 41384-41391 NN denotes potency
T14959 41392-41394 IN denotes of
T14960 41395-41398 DT denotes the
T14961 41399-41405 NN denotes GC-box
T14962 41406-41409 VB denotes was
T14963 41410-41417 RB denotes further
T14964 41418-41430 VB denotes demonstrated
T14965 41431-41433 IN denotes by
T14966 41434-41441 VB denotes cloning
T14967 41442-41444 PRP denotes it
T14968 41445-41453 RB denotes upstream
T14969 41454-41456 IN denotes of
T14970 41457-41459 DT denotes an
T14971 41460-41464 NN denotes SV40
T14972 41465-41473 NN denotes promoter
T14973 41475-41479 DT denotes This
T14974 41480-41488 VB denotes resulted
T14975 41489-41491 IN denotes in
T14976 41492-41493 DT denotes a
T14977 41494-41500 RB denotes 4-fold
T14978 41501-41509 VB denotes enhanced
T14979 41510-41523 NN denotes transcription
T14980 41524-41528 NN denotes rate
T14981 41530-41533 DT denotes The
T14982 41534-41544 NN denotes hypothesis
T14983 41545-41549 IN denotes that
T14984 41550-41551 DT denotes a
T14985 41552-41559 JJ denotes general
T14986 41560-41573 NN denotes transcription
T14987 41574-41580 NN denotes factor
T14988 41581-41583 VB denotes is
T14989 41584-41592 VB denotes involved
T14990 41593-41595 IN denotes in
T14991 41596-41606 NN denotes regulation
T14992 41607-41609 IN denotes of
T14993 41610-41613 NN denotes A3G
T14994 41614-41627 NN denotes transcription
T14995 41628-41631 VB denotes was
T14996 41632-41641 VB denotes confirmed
T14997 41642-41644 IN denotes by
T14998 41645-41649 NN denotes EMSA
T14999 41651-41661 NN denotes Supershift
T15000 41662-41670 NN denotes analysis
T15001 41671-41677 VB denotes showed
T15002 41678-41682 IN denotes that
T15003 41683-41686 DT denotes the
T15004 41687-41700 NN denotes transcription
T15005 41701-41708 NN denotes factors
T15006 41709-41712 NN denotes Sp1
T15007 41713-41716 CC denotes and
T15008 41717-41720 NN denotes Sp3
T15009 41721-41726 WDT denotes which
T15010 41727-41730 VB denotes are
T15011 41731-41743 RB denotes ubiquitously
T15012 41744-41753 VB denotes expressed
T15013 41754-41756 IN denotes in
T15014 41757-41766 JJ denotes mammalian
T15015 41767-41772 NN denotes cells
T15016 41772-41773 -COMMA- denotes ,
T15017 41774-41778 VB denotes bind
T15018 41779-41791 RB denotes specifically
T15019 41792-41794 TO denotes to
T15020 41795-41798 DT denotes the
T15021 41799-41809 VB denotes identified
T15022 41810-41815 NN denotes motif
T15023 41817-41819 IN denotes In
T15024 41820-41828 NN denotes addition
T15025 41828-41829 -COMMA- denotes ,
T15026 41830-41833 DT denotes the
T15027 41834-41841 NN denotes binding
T15028 41842-41844 IN denotes of
T15029 41845-41848 NN denotes Sp1
T15030 41849-41852 CC denotes and
T15031 41853-41856 NN denotes Sp3
T15032 41857-41859 TO denotes to
T15033 41860-41863 DT denotes the
T15034 41864-41874 JJ denotes endogenous
T15035 41875-41878 NN denotes A3G
T15036 41879-41887 NN denotes promoter
T15037 41888-41891 VB denotes was
T15038 41892-41904 VB denotes demonstrated
T15039 41905-41907 IN denotes by
T15040 41908-41909 DT denotes a
T15041 41910-41919 NN denotes chromatin
T15042 41920-41939 NN denotes immunoprecipitation
T15043 41940-41945 NN denotes assay
T15044 41947-41951 DT denotes This
T15045 41952-41963 NN denotes observation
T15046 41964-41966 VB denotes is
T15047 41967-41977 JJ denotes consistent
T15048 41978-41982 IN denotes with
T15049 41983-41986 DT denotes the
T15050 41987-41994 NN denotes results
T15051 41995-41997 IN denotes of
T15052 41998-42001 DT denotes the
T15053 42002-42009 NN denotes 5′-RACE
T15054 42009-42010 -COMMA- denotes ,
T15055 42011-42016 IN denotes since
T15056 42017-42020 NN denotes Sp1
T15057 42021-42023 VB denotes is
T15058 42024-42029 VB denotes known
T15059 42030-42032 TO denotes to
T15060 42033-42037 VB denotes play
T15061 42038-42040 DT denotes an
T15062 42041-42050 JJ denotes important
T15063 42051-42055 NN denotes role
T15064 42056-42059 IN denotes for
T15065 42060-42063 NN denotes RNA
T15066 42064-42074 NN denotes polymerase
T15067 42075-42077 CD denotes II
T15068 42078-42080 TO denotes to
T15069 42081-42085 VB denotes bind
T15070 42086-42088 TO denotes to
T15071 42089-42092 DT denotes the
T15072 42093-42106 NN denotes transcription
T15073 42107-42117 NN denotes initiation
T15074 42118-42122 NN denotes site
T15075 42123-42125 IN denotes in
T15076 42126-42138 JJ denotes TATA-boxless
T15077 42139-42148 NN denotes promoters
T15078 42149-42152 CC denotes and
T15079 42153-42155 VB denotes is
T15080 42156-42166 VB denotes associated
T15081 42167-42171 IN denotes with
T15082 42172-42180 JJ denotes multiple
T15083 42181-42194 NN denotes transcription
T15084 42195-42205 NN denotes initiation
T15085 42206-42211 NN denotes sites
T15086 42212-42213 -LRB- denotes (
T15087 42213-42218 CD denotes 54–56
T15088 42218-42219 -RRB- denotes )
T15089 42221-42223 PRP denotes We
T15090 42224-42228 RB denotes also
T15091 42229-42235 VB denotes tested
T15092 42236-42243 IN denotes whether
T15093 42244-42258 NN denotes overexpression
T15094 42259-42261 IN denotes of
T15095 42262-42265 NN denotes Sp1
T15096 42266-42268 CC denotes or
T15097 42269-42272 NN denotes Sp3
T15098 42273-42281 NN denotes proteins
T15099 42282-42285 VB denotes had
T15100 42286-42288 DT denotes an
T15101 42289-42298 NN denotes influence
T15102 42299-42301 IN denotes on
T15103 42302-42305 NN denotes A3G
T15104 42306-42314 NN denotes promoter
T15105 42315-42323 NN denotes activity
T15106 42325-42335 NN denotes Luciferase
T15107 42336-42342 NN denotes assays
T15108 42343-42351 VB denotes revealed
T15109 42352-42356 IN denotes that
T15110 42357-42360 NN denotes A3G
T15111 42361-42369 NN denotes promoter
T15112 42370-42380 NN denotes activities
T15113 42381-42389 VB denotes remained
T15114 42390-42399 JJ denotes unchanged
T15115 42400-42401 -LRB- denotes (
T15116 42401-42405 NN denotes data
T15117 42406-42409 RB denotes not
T15118 42410-42415 VB denotes shown
T15119 42415-42416 -RRB- denotes )
T15120 42416-42417 -COMMA- denotes ,
T15121 42418-42422 RB denotes most
T15122 42423-42431 RB denotes probably
T15123 42432-42435 JJ denotes due
T15124 42436-42438 TO denotes to
T15125 42439-42442 DT denotes the
T15126 42443-42447 JJ denotes high
T15127 42448-42453 JJ denotes basal
T15128 42454-42464 NN denotes expression
T15129 42465-42470 NN denotes level
T15130 42471-42473 IN denotes of
T15131 42474-42477 DT denotes the
T15132 42478-42488 JJ denotes endogenous
T15133 42489-42492 NN denotes Sp1
T15134 42493-42499 CC denotes and/or
T15135 42500-42503 NN denotes Sp3
T15136 42504-42512 NN denotes proteins
T15137 42514-42517 DT denotes The
T15138 42518-42520 NN denotes Sp
T15139 42521-42527 NN denotes family
T15140 42528-42530 IN denotes of
T15141 42531-42544 NN denotes transcription
T15142 42545-42552 NN denotes factors
T15143 42553-42555 VB denotes is
T15144 42556-42564 VB denotes involved
T15145 42565-42567 IN denotes in
T15146 42568-42583 JJ denotes transcriptional
T15147 42584-42594 NN denotes regulation
T15148 42595-42597 IN denotes of
T15149 42598-42602 JJ denotes many
T15150 42603-42615 NN denotes housekeeping
T15151 42615-42616 -COMMA- denotes ,
T15152 42617-42632 JJ denotes tissue-specific
T15153 42632-42633 -COMMA- denotes ,
T15154 42634-42639 JJ denotes viral
T15155 42640-42643 CC denotes and
T15156 42644-42653 JJ denotes inducible
T15157 42654-42659 NN denotes genes
T15158 42660-42661 -LRB- denotes (
T15159 42661-42663 CD denotes 57
T15160 42663-42664 -RRB- denotes )
T15161 42666-42673 IN denotes Whereas
T15162 42674-42677 NN denotes Sp1
T15163 42678-42687 RB denotes typically
T15164 42688-42692 VB denotes acts
T15165 42693-42695 IN denotes as
T15166 42696-42698 DT denotes an
T15167 42699-42708 NN denotes activator
T15168 42708-42709 -COMMA- denotes ,
T15169 42710-42713 NN denotes Sp3
T15170 42714-42717 MD denotes can
T15171 42718-42723 VB denotes serve
T15172 42724-42726 IN denotes as
T15173 42727-42728 DT denotes a
T15174 42729-42738 NN denotes repressor
T15175 42739-42741 CC denotes or
T15176 42742-42751 NN denotes activator
T15177 42752-42753 -LRB- denotes (
T15178 42753-42755 CD denotes 57
T15179 42755-42756 -RRB- denotes )
T15180 42758-42765 RB denotes However
T15181 42765-42766 -COMMA- denotes ,
T15182 42767-42769 IN denotes in
T15183 42770-42773 DT denotes the
T15184 42774-42781 NN denotes context
T15185 42782-42784 IN denotes of
T15186 42785-42788 DT denotes the
T15187 42789-42792 NN denotes A3G
T15188 42793-42801 NN denotes promoter
T15189 42801-42802 -COMMA- denotes ,
T15190 42803-42807 DT denotes both
T15191 42808-42821 NN denotes transcription
T15192 42822-42829 NN denotes factors
T15193 42830-42835 VB denotes serve
T15194 42836-42838 IN denotes as
T15195 42839-42849 NN denotes activators
T15196 42849-42850 -COMMA- denotes ,
T15197 42851-42853 IN denotes as
T15198 42854-42859 VB denotes shown
T15199 42860-42862 IN denotes by
T15200 42863-42877 JJ denotes siRNA-mediated
T15201 42878-42887 NN denotes silencing
T15202 42888-42890 IN denotes of
T15203 42891-42894 DT denotes the
T15204 42895-42901 JJ denotes single
T15205 42902-42909 NN denotes factors
T15206 42911-42919 IN denotes Although
T15207 42920-42926 NN denotes siRNAs
T15208 42927-42935 VB denotes directed
T15209 42936-42943 IN denotes against
T15210 42944-42947 NN denotes Sp1
T15211 42948-42950 CC denotes or
T15212 42951-42954 NN denotes Sp3
T15213 42955-42968 RB denotes significantly
T15214 42969-42976 VB denotes reduced
T15215 42977-42990 NN denotes transcription
T15216 42991-43001 VB denotes controlled
T15217 43002-43004 IN denotes by
T15218 43005-43008 DT denotes the
T15219 43009-43015 NN denotes 180 bp
T15220 43016-43024 NN denotes promoter
T15221 43024-43025 -COMMA- denotes ,
T15222 43026-43041 JJ denotes transcriptional
T15223 43042-43050 NN denotes activity
T15224 43051-43054 VB denotes was
T15225 43055-43058 RB denotes not
T15226 43059-43066 VB denotes reduced
T15227 43067-43069 TO denotes to
T15228 43070-43073 DT denotes the
T15229 43074-43079 NN denotes level
T15230 43080-43082 IN denotes of
T15231 43083-43086 DT denotes the
T15232 43087-43093 NN denotes 150 bp
T15233 43094-43102 NN denotes fragment
T15234 43104-43108 DT denotes This
T15235 43109-43112 MD denotes can
T15236 43113-43115 VB denotes be
T15237 43116-43125 VB denotes explained
T15238 43126-43128 IN denotes by
T15239 43129-43132 DT denotes the
T15240 43133-43142 VB denotes remaining
T15241 43143-43146 JJ denotes low
T15242 43147-43154 NN denotes amounts
T15243 43155-43157 IN denotes of
T15244 43158-43165 NN denotes Sp1/Sp3
T15245 43166-43174 NN denotes proteins
T15246 43175-43180 WDT denotes which
T15247 43181-43184 MD denotes can
T15248 43185-43187 VB denotes be
T15249 43188-43192 VB denotes seen
T15250 43193-43195 IN denotes in
T15251 43196-43199 DT denotes the
T15252 43200-43207 JJ denotes western
T15253 43208-43212 NN denotes blot
T15254 43213-43221 NN denotes analysis
T15255 43223-43236 RB denotes Alternatively
T15256 43236-43237 -COMMA- denotes ,
T15257 43238-43243 JJ denotes other
T15258 43244-43257 NN denotes transcription
T15259 43258-43265 NN denotes factors
T15260 43266-43271 MD denotes could
T15261 43272-43274 VB denotes be
T15262 43275-43283 VB denotes involved
T15263 43284-43286 IN denotes in
T15264 43287-43290 NN denotes A3G
T15265 43291-43301 NN denotes regulation
T15266 43303-43306 PRP-DOLLAR- denotes Our
T15267 43307-43314 NN denotes results
T15268 43315-43319 RB denotes also
T15269 43320-43327 VB denotes provide
T15270 43328-43339 NN denotes information
T15271 43340-43345 IN denotes about
T15272 43346-43349 DT denotes the
T15273 43350-43360 NN denotes regulation
T15274 43361-43363 IN denotes of
T15275 43364-43372 NN denotes APOBEC3F
T15276 43373-43374 -LRB- denotes (
T15277 43374-43377 NN denotes A3F
T15278 43377-43378 -RRB- denotes )
T15279 43378-43379 -COMMA- denotes ,
T15280 43380-43387 DT denotes another
T15281 43388-43394 NN denotes member
T15282 43395-43397 IN denotes of
T15283 43398-43401 DT denotes the
T15284 43402-43407 JJ denotes human
T15285 43408-43415 NN denotes APOBEC3
T15286 43416-43422 NN denotes family
T15287 43424-43427 NN denotes A3F
T15288 43428-43430 VB denotes is
T15289 43431-43440 VB denotes expressed
T15290 43441-43443 IN denotes in
T15291 43444-43448 JJ denotes many
T15292 43449-43454 JJ denotes human
T15293 43455-43462 NN denotes tissues
T15294 43463-43467 WDT denotes that
T15295 43468-43472 RB denotes also
T15296 43473-43480 VB denotes express
T15297 43481-43484 NN denotes A3G
T15298 43485-43488 CC denotes and
T15299 43489-43493 DT denotes both
T15300 43494-43502 NN denotes proteins
T15301 43503-43507 VB denotes have
T15302 43508-43512 VB denotes been
T15303 43513-43518 VB denotes shown
T15304 43519-43521 TO denotes to
T15305 43522-43526 VB denotes form
T15306 43527-43542 NN denotes heteromultimers
T15307 43542-43543 -COMMA- denotes ,
T15308 43544-43549 WDT denotes which
T15309 43550-43553 VB denotes are
T15310 43554-43558 RB denotes most
T15311 43559-43565 RB denotes likely
T15312 43566-43575 VB denotes generated
T15313 43576-43583 IN denotes through
T15314 43584-43591 NN denotes binding
T15315 43592-43594 TO denotes to
T15316 43595-43597 DT denotes an
T15317 43598-43601 NN denotes RNA
T15318 43602-43614 NN denotes intermediate
T15319 43615-43616 -LRB- denotes (
T15320 43616-43624 CD denotes 26,29,30
T15321 43624-43625 -RRB- denotes )
T15322 43627-43630 NN denotes A3F
T15323 43631-43635 RB denotes only
T15324 43636-43643 VB denotes differs
T15325 43644-43646 IN denotes in
T15326 43647-43652 NN denotes 16 nt
T15327 43653-43657 IN denotes from
T15328 43658-43661 DT denotes the
T15329 43662-43668 NN denotes 560 nt
T15330 43669-43677 RB denotes upstream
T15331 43678-43680 IN denotes of
T15332 43681-43684 DT denotes the
T15333 43685-43688 NN denotes TSS
T15334 43689-43691 IN denotes of
T15335 43692-43695 NN denotes A3G
T15336 43696-43697 -LRB- denotes (
T15337 43697-43705 NN denotes GenBank™
T15338 43706-43714 NN denotes DQ146365
T15339 43715-43718 CC denotes and
T15340 43719-43727 NN denotes DQ147772
T15341 43727-43728 -RRB- denotes )
T15342 43730-43733 DT denotes The
T15343 43734-43740 JJ denotes 180-bp
T15344 43741-43745 NN denotes core
T15345 43746-43754 NN denotes promoter
T15346 43755-43761 NN denotes region
T15347 43761-43762 -COMMA- denotes ,
T15348 43763-43768 WDT denotes which
T15349 43769-43771 PRP denotes we
T15350 43772-43782 VB denotes identified
T15351 43783-43786 IN denotes for
T15352 43787-43790 NN denotes A3G
T15353 43791-43794 VB denotes has
T15354 43795-43798 CD denotes 100
T15355 43798-43799 NN denotes %
T15356 43800-43808 NN denotes identity
T15357 43809-43813 IN denotes with
T15358 43814-43817 DT denotes the
T15359 43818-43821 NN denotes A3F
T15360 43822-43830 NN denotes sequence
T15361 43832-43841 RB denotes Therefore
T15362 43841-43842 -COMMA- denotes ,
T15363 43843-43850 NN denotes Sp1/Sp3
T15364 43851-43864 NN denotes transcription
T15365 43865-43872 NN denotes factors
T15366 43873-43876 VB denotes are
T15367 43877-43881 RB denotes most
T15368 43882-43888 RB denotes likely
T15369 43889-43893 RB denotes also
T15370 43894-43903 VB denotes mediating
T15371 43904-43909 JJ denotes basal
T15372 43910-43923 NN denotes transcription
T15373 43924-43926 IN denotes of
T15374 43927-43930 DT denotes the
T15375 43931-43934 NN denotes A3F
T15376 43935-43939 NN denotes gene
T15377 43941-43944 PRP-DOLLAR- denotes Our
T15378 43945-43950 NN denotes study
T15379 43951-43959 VB denotes revealed
T15380 43960-43964 IN denotes that
T15381 43965-43968 DT denotes the
T15382 43969-43974 JJ denotes human
T15383 43975-43978 NN denotes A3G
T15384 43979-43983 NN denotes gene
T15385 43984-43986 VB denotes is
T15386 43987-43997 VB denotes controlled
T15387 43998-44000 IN denotes by
T15388 44001-44002 DT denotes a
T15389 44003-44011 NN denotes promoter
T15390 44012-44016 IN denotes with
T15391 44017-44025 JJ denotes multiple
T15392 44026-44041 JJ denotes transcriptional
T15393 44042-44047 NN denotes start
T15394 44048-44053 NN denotes sites
T15395 44055-44057 IN denotes In
T15396 44058-44065 NN denotes A3.01 T
T15397 44066-44071 NN denotes cells
T15398 44071-44072 -COMMA- denotes ,
T15399 44073-44076 DT denotes the
T15400 44077-44080 NN denotes A3G
T15401 44081-44089 NN denotes promoter
T15402 44090-44097 VB denotes appears
T15403 44098-44112 RB denotes constitutively
T15404 44113-44119 JJ denotes active
T15405 44120-44123 CC denotes and
T15406 44124-44126 VB denotes is
T15407 44127-44130 RB denotes not
T15408 44131-44140 JJ denotes inducible
T15409 44141-44143 IN denotes by
T15410 44144-44147 NN denotes TPA
T15411 44147-44148 -COMMA- denotes ,
T15412 44149-44153 NN denotes type
T15413 44154-44155 CD denotes I
T15414 44156-44158 CC denotes or
T15415 44159-44161 CD denotes II
T15416 44162-44173 NN denotes interferons
T15417 44174-44176 CC denotes or
T15418 44177-44179 IN denotes by
T15419 44180-44185 NN denotes HIV-1
T15420 44186-44194 NN denotes proteins
T15421 44196-44199 DT denotes The
T15422 44200-44204 NN denotes core
T15423 44205-44213 NN denotes promoter
T15424 44214-44216 VB denotes is
T15425 44217-44224 JJ denotes located
T15426 44225-44231 IN denotes within
T15427 44232-44233 DT denotes a
T15428 44234-44240 NN denotes region
T15429 44241-44243 IN denotes of
T15430 44244-44250 NN denotes 180 bp
T15431 44251-44253 IN denotes at
T15432 44254-44262 NN denotes position
T15433 44263-44271 CD denotes −114/+66
T15434 44272-44280 JJ denotes relative
T15435 44281-44283 TO denotes to
T15436 44284-44287 DT denotes the
T15437 44288-44291 NN denotes TSS
T15438 44293-44294 DT denotes A
T15439 44295-44301 NN denotes GC-box
T15440 44302-44304 VB denotes is
T15441 44305-44312 JJ denotes crucial
T15442 44313-44315 TO denotes to
T15443 44316-44319 DT denotes the
T15444 44320-44328 NN denotes function
T15445 44329-44331 IN denotes of
T15446 44332-44335 DT denotes the
T15447 44336-44340 NN denotes core
T15448 44341-44349 NN denotes promoter
T15449 44350-44353 CC denotes and
T15450 44354-44364 VB denotes represents
T15451 44365-44366 DT denotes a
T15452 44367-44374 VB denotes binding
T15453 44375-44379 NN denotes site
T15454 44380-44383 IN denotes for
T15455 44384-44387 NN denotes Sp1
T15456 44388-44391 CC denotes and
T15457 44392-44395 NN denotes Sp3
T15458 44396-44409 NN denotes transcription
T15459 44410-44417 NN denotes factors
T15460 44419-44422 PRP-DOLLAR- denotes Our
T15461 44423-44430 NN denotes results
T15462 44431-44434 MD denotes can
T15463 44435-44440 VB denotes serve
T15464 44441-44443 IN denotes as
T15465 44444-44445 DT denotes a
T15466 44446-44451 NN denotes basis
T15467 44452-44455 IN denotes for
T15468 44456-44462 JJ denotes future
T15469 44463-44470 NN denotes studies
T15470 44471-44476 VB denotes aimed
T15471 44477-44479 IN denotes at
T15472 44480-44493 VB denotes understanding
T15473 44494-44497 WRB denotes how
T15474 44498-44501 NN denotes A3G
T15475 44502-44505 CC denotes and
T15476 44506-44509 NN denotes A3F
T15477 44510-44520 NN denotes expression
T15478 44521-44523 VB denotes is
T15479 44524-44534 VB denotes controlled
T15480 44535-44537 IN denotes in
T15481 44538-44547 JJ denotes different
T15482 44548-44555 NN denotes tissues
T15483 44556-44559 CC denotes and
T15484 44560-44563 WRB denotes how
T15485 44564-44569 DT denotes these
T15486 44570-44581 NN denotes restriction
T15487 44582-44589 NN denotes factors
T15488 44590-44593 MD denotes can
T15489 44594-44596 VB denotes be
T15490 44597-44601 VB denotes used
T15491 44602-44604 TO denotes to
T15492 44605-44612 VB denotes develop
T15493 44613-44618 JJ denotes novel
T15494 44619-44630 JJ denotes therapeutic
T15495 44631-44641 NN denotes strategies
T15496 44642-44649 IN denotes against
T15497 44650-44655 NN denotes HIV-1
T15498 44656-44665 NN denotes infection
R100 T133 T130 arg2Of factor,of
R1000 T1212 T1211 arg1Of processing,mRNA
R1001 T1212 T1213 arg1Of processing,(
R1002 T1214 T1213 arg2Of P,(
R1003 T1215 T1213 arg3Of ),(
R1004 T1216 T1209 arg2Of bodies,localize
R1005 T1216 T1217 arg1Of bodies,","
R1006 T1219 T1217 arg2Of compartments,","
R1007 T1219 T1218 arg1Of compartments,cytoplasmic
R1008 T1219 T1220 arg2Of compartments,involved
R1009 T1220 T1221 arg1Of involved,in
R101 T133 T131 arg1Of factor,this
R1010 T1223 T1224 arg1Of degradation,and
R1011 T1224 T1221 arg2Of and,in
R1012 T1224 T1222 arg1Of and,the
R1013 T1224 T1226 arg1Of and,of
R1014 T1225 T1224 arg2Of storage,and
R1015 T1228 T1226 arg2Of mRNAs,of
R1016 T1228 T1227 arg1Of mRNAs,non-translating
R1017 T1228 T1229 arg1Of mRNAs,(
R1018 T1230 T1229 arg2Of "30,31",(
R1019 T1231 T1229 arg3Of ),(
R102 T133 T132 arg1Of factor,restriction
R1020 T1232 T1233 arg1Of A3G,has
R1021 T1232 T1234 arg1Of A3G,been
R1022 T1232 T1235 arg2Of A3G,shown
R1023 T1232 T1237 arg1Of A3G,be
R1024 T1232 T1238 arg2Of A3G,expressed
R1025 T1235 T1233 arg2Of shown,has
R1026 T1235 T1234 arg2Of shown,been
R1027 T1235 T1252 arg1Of shown,but
R1028 T1238 T1235 arg3Of expressed,shown
R1029 T1238 T1236 arg1Of expressed,to
R103 T135 T123 arg1Of we,gain
R1030 T1238 T1237 arg2Of expressed,be
R1031 T1238 T1239 arg1Of expressed,in
R1032 T1241 T1239 arg2Of cells,in
R1033 T1241 T1240 arg1Of cells,T
R1034 T1241 T1242 arg1Of cells,","
R1035 T1246 T1242 arg2Of target,","
R1036 T1246 T1243 arg1Of target,a
R1037 T1246 T1244 arg1Of target,relevant
R1038 T1246 T1245 arg1Of target,cell
R1039 T1246 T1247 arg1Of target,for
R104 T135 T136 arg1Of we,cloned
R1040 T1248 T1247 arg2Of HIV-1,for
R1041 T1248 T1250 arg1Of HIV-1,vivo
R1042 T1250 T1249 arg1Of vivo,in
R1043 T1252 T1251 arg1Of but,","
R10431 T12901 T12902 arg1Of Silencing,of
R10432 T12901 T12906 arg1Of Silencing,reduces
R10433 T12903 T12904 arg1Of Sp1,and
R10434 T12904 T12902 arg2Of and,of
R10435 T12905 T12904 arg2Of Sp3,and
R10436 T12909 T12907 arg1Of activity,A3G
R10437 T12909 T12908 arg1Of activity,promoter
R10438 T12909 T12906 arg2Of activity,reduces
R10439 T12911 T12910 arg1Of confirm,To
R1044 T1253 T1254 arg1Of little,is
R10440 T12913 T12911 arg2Of role,confirm
R10441 T12913 T12912 arg1Of role,the
R10442 T12913 T12914 arg1Of role,of
R10443 T12913 T12918 arg1Of role,in
R10444 T12915 T12916 arg1Of Sp1,and
R10445 T12916 T12914 arg2Of and,of
R10446 T12917 T12916 arg2Of Sp3,and
R10447 T12919 T12918 arg2Of regulation,in
R10448 T12919 T12920 arg1Of regulation,of
R10449 T12923 T12920 arg2Of activity,of
R1045 T1253 T1255 arg2Of little,known
R10450 T12923 T12921 arg1Of activity,A3G
R10451 T12923 T12922 arg1Of activity,promoter
R10452 T12925 T12911 arg1Of we,confirm
R10453 T12925 T12926 arg1Of we,silenced
R10454 T12926 T12910 modOf silenced,To
R10455 T12926 T12924 arg1Of silenced,","
R10456 T12926 T12929 arg1Of silenced,via
R10457 T12928 T12926 arg2Of translation,silenced
R10458 T12928 T12927 arg1Of translation,their
R10459 T12931 T12929 arg2Of interference,via
R1046 T1255 T1252 arg2Of known,but
R10460 T12931 T12930 arg1Of interference,RNA
R10461 T12932 T12933 arg1Of Functionality,of
R10462 T12932 T12941 arg1Of Functionality,was
R10463 T12932 T12942 arg2Of Functionality,confirmed
R10464 T12935 T12933 arg2Of siRNAs,of
R10465 T12935 T12934 arg1Of siRNAs,the
R10466 T12935 T12936 arg2Of siRNAs,directed
R10467 T12936 T12937 arg1Of directed,against
R10468 T12938 T12939 arg1Of Sp1,or
R10469 T12939 T12937 arg2Of or,against
R1047 T1255 T1254 arg2Of known,is
R10470 T12940 T12939 arg2Of Sp3,or
R10471 T12942 T12941 arg2Of confirmed,was
R10472 T12946 T12942 arg1Of analysis,confirmed
R10473 T12946 T12943 arg2Of analysis,by
R10474 T12946 T12944 arg1Of analysis,western
R10475 T12946 T12945 arg1Of analysis,blot
R10476 T12946 T12962 modOf analysis,were
R10477 T12949 T12948 arg1Of levels,protein
R10478 T12949 T12950 arg1Of levels,of
R10479 T12949 T12954 arg1Of levels,as
R1048 T1255 T1256 arg1Of known,about
R10480 T12951 T12950 arg2Of Sp1,of
R10481 T12954 T12952 arg1Of as,as
R10482 T12954 T12953 arg1Of as,well
R10483 T12954 T12962 arg1Of as,were
R10484 T12954 T12964 arg2Of as,reduced
R10485 T12956 T12957 arg1Of long,and
R10486 T12958 T12957 arg2Of short,and
R10487 T12959 T12954 arg2Of isoforms,as
R10488 T12959 T12955 arg1Of isoforms,the
R10489 T12959 T12956 arg1Of isoforms,long
R1049 T1258 T1256 arg2Of regulation,about
R10490 T12959 T12958 arg1Of isoforms,short
R10491 T12959 T12960 arg1Of isoforms,of
R10492 T12961 T12960 arg2Of Sp3,of
R10493 T12964 T12947 arg1Of reduced,:
R10494 T12964 T12962 arg2Of reduced,were
R10495 T12964 T12963 arg1Of reduced,strongly
R10496 T12964 T12965 arg1Of reduced,in
R10497 T12967 T12965 arg2Of presence,in
R10498 T12967 T12966 arg1Of presence,the
R10499 T12967 T12968 arg1Of presence,of
R105 T135 T138 arg1Of we,characterized
R1050 T1258 T1257 arg1Of regulation,its
R10500 T12969 T12970 arg1Of 150,or
R10501 T12971 T12970 arg2Of 300 ng,or
R10502 T12972 T12969 arg1Of specific,150
R10503 T12972 T12971 arg1Of specific,300 ng
R10504 T12973 T12968 arg2Of siRNA,of
R10505 T12973 T12972 arg1Of siRNA,specific
R10506 T12973 T12974 arg1Of siRNA,(
R10507 T12976 T12974 arg2Of 7A,(
R10508 T12976 T12975 arg1Of 7A,Figure
R10509 T12977 T12974 arg3Of ),(
R1051 T1258 T1259 arg1Of regulation,(
R10510 T12981 T12978 arg1Of siRNA,An
R10511 T12981 T12979 arg1Of siRNA,unspecific
R10512 T12981 T12980 arg1Of siRNA,control
R10513 T12981 T12982 arg1Of siRNA,had
R10514 T12984 T12982 arg2Of influence,had
R10515 T12984 T12983 arg1Of influence,no
R10516 T12984 T12985 arg1Of influence,(
R10517 T12987 T12985 arg2Of 7A,(
R10518 T12987 T12986 arg1Of 7A,Figure
R10519 T12988 T12985 arg3Of ),(
R1052 T1260 T1259 arg2Of "4,29,32",(
R10520 T12989 T12991 arg1Of We,cotransfected
R10521 T12991 T12990 arg1Of cotransfected,then
R10522 T12995 T12991 arg2Of plasmid,cotransfected
R10523 T12995 T12992 arg1Of plasmid,the
R10524 T12995 T12993 arg1Of plasmid,luciferase
R10525 T12995 T12994 arg1Of plasmid,reporter
R10526 T12995 T12996 arg1Of plasmid,containing
R10527 T12996 T13002 arg1Of containing,with
R10528 T13000 T12996 arg2Of promoter,containing
R10529 T13000 T12997 arg1Of promoter,the
R1053 T1261 T1259 arg3Of ),(
R10530 T13000 T12998 arg1Of promoter,180 bp
R10531 T13000 T12999 arg1Of promoter,A3G
R10532 T13000 T13001 arg1Of promoter,together
R10533 T13004 T13002 arg2Of siRNA,with
R10534 T13004 T13003 arg1Of siRNA,100 ng
R10535 T13004 T13005 arg1Of siRNA,using
R10536 T13005 T13002 arg3Of using,with
R10537 T13008 T13005 arg2Of protocol,using
R10538 T13008 T13006 arg1Of protocol,an
R10539 T13008 T13007 arg2Of protocol,optimized
R1054 T1262 T1263 arg1Of There,is
R10540 T13008 T13009 arg1Of protocol,for
R10541 T13011 T13009 arg2Of cotransfection,for
R10542 T13011 T13010 arg1Of cotransfection,the
R10543 T13011 T13012 arg1Of cotransfection,of
R10544 T13013 T13014 arg1Of plasmid,plus
R10545 T13014 T13012 arg2Of plus,of
R10546 T13015 T13014 arg2Of siRNA,plus
R10547 T13016 T13017 arg1Of This,resulted
R10548 T13017 T13018 arg1Of resulted,in
R10549 T13017 T13026 arg1Of resulted,in
R1055 T1263 T1266 modOf is,describing
R10550 T13020 T13021 arg1Of 31–43,%
R10551 T13022 T13018 arg2Of reduction,in
R10552 T13022 T13019 arg1Of reduction,a
R10553 T13022 T13020 arg1Of reduction,31–43
R10554 T13022 T13023 arg1Of reduction,of
R10555 T13025 T13023 arg2Of activity,of
R10556 T13025 T13024 arg1Of activity,luciferase
R10557 T13028 T13026 arg2Of presence,in
R10558 T13028 T13027 arg1Of presence,the
R10559 T13028 T13029 arg1Of presence,of
R1056 T1263 T1278 arg1Of is,but
R10560 T13028 T13034 arg1Of presence,compared
R10561 T13030 T13031 arg1Of Sp1-,or
R10562 T13031 T13029 arg2Of or,of
R10563 T13033 T13031 arg2Of siRNA,or
R10564 T13033 T13032 arg1Of siRNA,Sp3-specific
R10565 T13035 T13034 arg2Of to,compared
R10566 T13038 T13035 arg2Of siRNA,to
R10567 T13038 T13036 arg1Of siRNA,the
R10568 T13038 T13037 arg1Of siRNA,control
R10569 T13040 T13039 arg2Of contrast,In
R1057 T1265 T1264 arg1Of report,a
R10570 T13043 T13042 arg1Of influence,no
R10571 T13043 T13044 arg1Of influence,on
R10572 T13043 T13060 arg1Of influence,was
R10573 T13043 T13061 arg2Of influence,observed
R10574 T13046 T13044 arg2Of activity,on
R10575 T13046 T13045 arg1Of activity,transcriptional
R10576 T13046 T13047 arg1Of activity,of
R10577 T13050 T13047 arg2Of fragment,of
R10578 T13050 T13048 arg1Of fragment,the
R10579 T13050 T13049 arg1Of fragment,150 bp
R1058 T1265 T1266 arg1Of report,describing
R10580 T13050 T13051 arg1Of fragment,","
R10581 T13050 T13052 arg1Of fragment,which
R10582 T13050 T13053 arg1Of fragment,does
R10583 T13050 T13055 arg1Of fragment,contain
R10584 T13055 T13053 arg2Of contain,does
R10585 T13055 T13054 arg1Of contain,not
R10586 T13058 T13055 arg2Of motif,contain
R10587 T13058 T13056 arg1Of motif,the
R10588 T13058 T13057 arg1Of motif,Sp1/Sp3-binding
R10589 T13061 T13039 arg1Of observed,In
R1059 T1269 T1266 arg2Of stimulation,describing
R10590 T13061 T13041 arg1Of observed,","
R10591 T13061 T13059 arg1Of observed,","
R10592 T13061 T13060 arg2Of observed,was
R10593 T13065 T13066 arg1Of Sp1,and
R10594 T13066 T13064 arg1Of and,both
R10595 T13067 T13066 arg2Of Sp3,and
R10596 T13068 T13065 arg1Of factors,Sp1
R10597 T13068 T13067 arg1Of factors,Sp3
R10598 T13068 T13069 arg1Of factors,are
R10599 T13068 T13070 arg1Of factors,mediating
R106 T136 T137 arg1Of cloned,and
R1060 T1269 T1267 arg1Of stimulation,that
R10600 T13070 T13062 arg1Of mediating,Thus
R10601 T13070 T13063 arg1Of mediating,","
R10602 T13070 T13069 arg2Of mediating,are
R10603 T13072 T13070 arg2Of activity,mediating
R10604 T13072 T13071 arg1Of activity,transcriptional
R10605 T13072 T13073 arg1Of activity,of
R10606 T13076 T13073 arg2Of promoter,of
R10607 T13076 T13074 arg1Of promoter,the
R10608 T13076 T13075 arg1Of promoter,A3G
R1061 T1269 T1268 arg1Of stimulation,mitogenic
R1062 T1269 T1270 arg1Of stimulation,of
R1063 T1272 T1270 arg2Of cells,of
R1064 T1272 T1271 arg1Of cells,T
R1065 T1276 T1263 arg2Of levels,is
R1066 T1276 T1273 arg1Of levels,upregulates
R1067 T1276 T1274 arg1Of levels,A3G
R1068 T1276 T1275 arg1Of levels,mRNA
R1069 T1278 T1277 arg1Of but,","
R107 T137 T122 modOf and,To
R1070 T1279 T1280 arg1Of this,was
R1071 T1279 T1282 arg2Of this,analyzed
R1072 T1282 T1278 arg2Of analyzed,but
R1073 T1282 T1280 arg2Of analyzed,was
R1074 T1282 T1281 arg1Of analyzed,not
R1075 T1282 T1283 arg1Of analyzed,on
R1076 T1286 T1283 arg2Of level,on
R1077 T1286 T1284 arg1Of level,the
R1078 T1286 T1285 arg1Of level,transcriptional
R1079 T1286 T1287 arg1Of level,(
R108 T137 T134 arg1Of and,","
R1080 T1288 T1287 arg2Of 33,(
R1081 T1289 T1287 arg3Of ),(
R1082 T1293 T1291 arg1Of promoter,the
R1083 T1293 T1292 arg1Of promoter,A3G
R1084 T1293 T1294 arg1Of promoter,has
R1085 T1293 T1296 arg1Of promoter,been
R1086 T1293 T1298 arg2Of promoter,analyzed
R1087 T1298 T1290 arg2Of analyzed,Since
R1088 T1298 T1294 arg2Of analyzed,has
R1089 T1298 T1295 arg1Of analyzed,not
R109 T138 T137 arg2Of characterized,and
R1090 T1298 T1296 arg2Of analyzed,been
R1091 T1298 T1297 arg1Of analyzed,systematically
R1092 T1298 T1300 arg1Of analyzed,far
R1093 T1300 T1299 arg1Of far,so
R1094 T1303 T1302 arg1Of aim,our
R1095 T1303 T1304 arg1Of aim,was
R1096 T1304 T1290 arg1Of was,Since
R1097 T1304 T1301 arg1Of was,","
R1098 T1306 T1310 arg1Of clone,and
R1099 T1309 T1306 arg2Of promoter,clone
R110 T141 T136 arg2Of region,cloned
R1100 T1309 T1307 arg1Of promoter,the
R1101 T1309 T1308 arg1Of promoter,A3G
R1102 T1310 T1304 arg2Of and,was
R1103 T1310 T1305 arg1Of and,to
R1104 T1311 T1310 arg2Of characterize,and
R1105 T1313 T1311 arg2Of regulation,characterize
R1106 T1313 T1312 arg1Of regulation,its
R1107 T1313 T1314 arg1Of regulation,in
R1108 T1316 T1314 arg2Of cells,in
R1109 T1316 T1315 arg1Of cells,T
R111 T141 T138 arg2Of region,characterized
R1110 T1319 T1317 arg2Of study,In
R1111 T1319 T1318 arg1Of study,our
R1112 T1321 T1322 arg1Of we,observed
R1113 T1322 T1317 arg1Of observed,In
R1114 T1322 T1320 arg1Of observed,","
R1115 T1324 T1325 arg1Of A3G,uses
R1116 T1325 T1322 arg2Of uses,observed
R1117 T1325 T1323 arg1Of uses,that
R1118 T1329 T1325 arg2Of sites,uses
R1119 T1329 T1326 arg1Of sites,multiple
R112 T141 T139 arg1Of region,the
R1120 T1329 T1327 arg1Of sites,transcriptional
R11201 T14081 T14080 arg1Of after,Shortly
R11202 T14083 T14081 arg2Of discovery,after
R11203 T14083 T14082 arg1Of discovery,the
R11204 T14083 T14084 arg1Of discovery,of
R11205 T14085 T14084 arg2Of APOBEC3G,of
R11206 T14087 T14088 arg1Of it,became
R11207 T14087 T14089 arg1Of it,clear
R11208 T14088 T14081 arg1Of became,after
R11209 T14088 T14086 arg1Of became,","
R1121 T1329 T1328 arg1Of sites,start
R11210 T14089 T14088 arg2Of clear,became
R11211 T14093 T14091 arg1Of gene,this
R11212 T14093 T14092 arg1Of gene,human
R11213 T14093 T14094 arg1Of gene,plays
R11214 T14094 T14089 arg2Of plays,clear
R11215 T14094 T14090 arg1Of plays,that
R11216 T14094 T14098 arg1Of plays,in
R11217 T14097 T14094 arg2Of role,plays
R11218 T14097 T14095 arg1Of role,an
R11219 T14097 T14096 arg1Of role,important
R1122 T1329 T1330 arg1Of sites,(
R11220 T14100 T14098 arg2Of defense,in
R11221 T14100 T14099 arg1Of defense,antiretroviral
R11222 T14100 T14101 arg1Of defense,(
R11223 T14102 T14101 arg2Of 4,(
R11224 T14103 T14101 arg3Of ),(
R11225 T14105 T14104 arg1Of identified,Originally
R11226 T14105 T14106 arg1Of identified,as
R11227 T14109 T14106 arg2Of factor,as
R11228 T14109 T14107 arg1Of factor,a
R11229 T14109 T14108 arg1Of factor,restriction
R1123 T1331 T1330 arg2Of TSS,(
R11230 T14109 T14110 arg1Of factor,of
R11231 T14112 T14110 arg2Of infection,of
R11232 T14112 T14111 arg1Of infection,HIV-1
R11233 T14114 T14105 arg2Of expression,identified
R11234 T14114 T14115 arg1Of expression,of
R11235 T14114 T14117 arg1Of expression,was
R11236 T14114 T14118 arg2Of expression,found
R11237 T14116 T14115 arg2Of APOBEC3G,of
R11238 T14118 T14105 modOf found,identified
R11239 T14118 T14113 arg1Of found,","
R1124 T1332 T1330 arg3Of ),(
R11240 T14118 T14117 arg2Of found,was
R11241 T14118 T14119 arg1Of found,in
R11242 T14123 T14120 arg1Of lymphocytes,human
R11243 T14123 T14121 arg1Of lymphocytes,peripheral
R11244 T14123 T14122 arg1Of lymphocytes,blood
R11245 T14123 T14124 arg1Of lymphocytes,and
R11246 T14124 T14119 arg2Of and,in
R11247 T14124 T14126 arg1Of and,","
R11248 T14124 T14127 arg1Of and,which
R11249 T14124 T14128 arg1Of and,represent
R1125 T1334 T1333 arg2Of generating,By
R11250 T14125 T14124 arg2Of macrophages,and
R11251 T14128 T14133 arg1Of represent,for
R11252 T14132 T14128 arg2Of cells,represent
R11253 T14132 T14129 arg1Of cells,the
R11254 T14132 T14130 arg1Of cells,main
R11255 T14132 T14131 arg1Of cells,target
R11256 T14134 T14133 arg2Of HIV-1,for
R11257 T14134 T14135 arg1Of HIV-1,(
R11258 T14136 T14135 arg2Of 32,(
R11259 T14137 T14135 arg3Of ),(
R1126 T1336 T1334 arg2Of series,generating
R11260 T14139 T14138 arg2Of addition,In
R11261 T14142 T14141 arg1Of protein,the
R11262 T14142 T14143 arg1Of protein,was
R11263 T14142 T14144 arg2Of protein,detected
R11264 T14144 T14143 arg2Of detected,was
R11265 T14144 T14145 arg1Of detected,in
R11266 T14144 T14156 arg1Of detected,but
R11267 T14146 T14147 arg1Of lung,","
R11268 T14147 T14149 arg1Of ",",","
R11269 T14148 T14147 arg2Of liver,","
R1127 T1336 T1335 arg1Of series,a
R11270 T14149 T14151 arg1Of ",",","
R11271 T14150 T14149 arg2Of spleen,","
R11272 T14151 T14153 arg1Of ",",and
R11273 T14152 T14151 arg2Of testis,","
R11274 T14153 T14145 arg2Of and,in
R11275 T14154 T14153 arg2Of ovary,and
R11276 T14156 T14138 arg1Of but,In
R11277 T14156 T14140 arg1Of but,","
R11278 T14156 T14155 arg1Of but,","
R11279 T14157 T14158 arg1Of little,is
R1128 T1336 T1337 arg1Of series,of
R11280 T14157 T14159 arg2Of little,known
R11281 T14159 T14156 arg2Of known,but
R11282 T14159 T14158 arg2Of known,is
R11283 T14159 T14160 arg1Of known,about
R11284 T14163 T14160 arg2Of regulation,about
R11285 T14163 T14161 arg1Of regulation,its
R11286 T14163 T14162 arg1Of regulation,transcriptional
R11287 T14163 T14164 arg1Of regulation,(
R11288 T14165 T14164 arg2Of "29,32,47",(
R11289 T14166 T14164 arg3Of ),(
R1129 T1339 T1337 arg2Of deletions,of
R11290 T14168 T14167 arg1Of address,To
R11291 T14170 T14168 arg2Of question,address
R11292 T14170 T14169 arg1Of question,this
R11293 T14172 T14168 arg1Of we,address
R11294 T14172 T14173 arg1Of we,cloned
R11295 T14172 T14179 arg1Of we,analyzed
R11296 T14173 T14178 arg1Of cloned,and
R11297 T14177 T14173 arg2Of promoter,cloned
R11298 T14177 T14174 arg1Of promoter,the
R11299 T14177 T14175 arg1Of promoter,human
R113 T141 T140 arg1Of region,promoter
R1130 T1339 T1338 arg1Of deletions,5′
R11300 T14177 T14176 arg1Of promoter,APOBEC3G
R11301 T14178 T14167 modOf and,To
R11302 T14178 T14171 arg1Of and,","
R11303 T14179 T14178 arg2Of analyzed,and
R11304 T14181 T14179 arg2Of regulation,analyzed
R11305 T14181 T14180 arg1Of regulation,its
R11306 T14181 T14182 arg1Of regulation,in
R11307 T14184 T14182 arg2Of cells,in
R11308 T14184 T14183 arg1Of cells,T
R11309 T14186 T14185 arg2Of 5′-RACE,Applying
R1131 T1339 T1340 arg1Of deletions,of
R11310 T14188 T14185 arg1Of we,Applying
R11311 T14188 T14189 arg1Of we,identified
R11312 T14189 T14185 modOf identified,Applying
R11313 T14189 T14187 arg1Of identified,","
R11314 T14192 T14189 arg2Of sites,identified
R11315 T14192 T14190 arg1Of sites,multiple
R11316 T14192 T14191 arg1Of sites,start
R11317 T14192 T14193 arg1Of sites,for
R11318 T14194 T14193 arg2Of transcription,for
R11319 T14194 T14195 arg1Of transcription,of
R1132 T1343 T1340 arg2Of promoter,of
R11320 T14198 T14195 arg2Of gene,of
R11321 T14198 T14196 arg1Of gene,the
R11322 T14198 T14197 arg1Of gene,A3G
R11323 T14200 T14199 arg1Of observation,This
R11324 T14200 T14201 arg1Of observation,is
R11325 T14200 T14202 arg1Of observation,consistent
R11326 T14202 T14201 arg2Of consistent,is
R11327 T14202 T14203 arg1Of consistent,with
R11328 T14205 T14203 arg2Of fact,with
R11329 T14205 T14204 arg1Of fact,the
R1133 T1343 T1341 arg1Of promoter,the
R11330 T14208 T14207 arg1Of gene,the
R11331 T14208 T14209 arg1Of gene,appears
R11332 T14208 T14211 arg1Of gene,lack
R11333 T14209 T14205 arg2Of appears,fact
R11334 T14209 T14206 arg1Of appears,that
R11335 T14211 T14209 arg2Of lack,appears
R11336 T14211 T14210 arg1Of lack,to
R11337 T14213 T14214 arg1Of CCAAT,and
R11338 T14215 T14214 arg2Of TATA,and
R11339 T14216 T14211 arg2Of boxes,lack
R1134 T1343 T1342 arg1Of promoter,A3G
R11340 T14216 T14212 arg1Of boxes,canonical
R11341 T14216 T14213 arg1Of boxes,CCAAT
R11342 T14216 T14215 arg1Of boxes,TATA
R11343 T14216 T14217 arg1Of boxes,(
R11344 T14216 T14220 arg1Of boxes,","
R11345 T14218 T14217 arg2Of 32,(
R11346 T14219 T14217 arg3Of ),(
R11347 T14222 T14220 arg2Of condition,","
R11348 T14222 T14221 arg1Of condition,a
R11349 T14222 T14224 arg2Of condition,associated
R1135 T1345 T1334 arg1Of we,generating
R11350 T14224 T14223 arg1Of associated,often
R11351 T14224 T14225 arg1Of associated,with
R11352 T14229 T14225 arg2Of sites,with
R11353 T14229 T14226 arg1Of sites,multiple
R11354 T14229 T14227 arg1Of sites,transcriptional
R11355 T14229 T14228 arg1Of sites,start
R11356 T14229 T14230 arg1Of sites,(
R11357 T14231 T14230 arg2Of 49–51,(
R11358 T14232 T14230 arg3Of ),(
R11359 T14238 T14235 arg1Of site,one
R1136 T1345 T1346 arg1Of we,identified
R11360 T14238 T14236 arg1Of site,single
R11361 T14238 T14237 arg1Of site,start
R11362 T14238 T14239 arg1Of site,was
R11363 T14238 T14240 arg2Of site,detected
R11364 T14238 T14247 arg1Of site,was
R11365 T14238 T14248 arg2Of site,designated
R11366 T14240 T14239 arg2Of detected,was
R11367 T14240 T14241 arg1Of detected,in
R11368 T14240 T14246 arg1Of detected,and
R11369 T14242 T14243 arg1Of 6,of
R1137 T1346 T1333 arg1Of identified,By
R11370 T14244 T14243 arg2Of 19,of
R11371 T14245 T14241 arg2Of clones,in
R11372 T14245 T14242 arg1Of clones,6
R11373 T14246 T14233 arg1Of and,However
R11374 T14246 T14234 arg1Of and,","
R11375 T14248 T14246 arg2Of designated,and
R11376 T14248 T14247 arg2Of designated,was
R11377 T14248 T14249 arg1Of designated,as
R11378 T14250 T14249 arg2Of +1,as
R11379 T14252 T14251 arg1Of TSS,This
R1138 T1346 T1344 arg1Of identified,","
R11380 T14252 T14253 arg1Of TSS,is
R11381 T14252 T14254 arg1Of TSS,located
R11382 T14254 T14253 arg2Of located,is
R11383 T14254 T14256 arg1Of located,upstream
R11384 T14256 T14255 arg1Of upstream,66 bp
R11385 T14256 T14257 arg1Of upstream,of
R11386 T14259 T14257 arg2Of start,of
R11387 T14259 T14258 arg1Of start,the
R11388 T14259 T14260 arg1Of start,of
R11389 T14264 T14260 arg2Of sequence,of
R1139 T1353 T1346 arg2Of transcription,identified
R11390 T14264 T14261 arg1Of sequence,the
R11391 T14264 T14262 arg2Of sequence,published
R11392 T14264 T14263 arg1Of sequence,mRNA
R11393 T14264 T14265 arg1Of sequence,(
R11394 T14267 T14265 arg2Of NM021822,(
R11395 T14267 T14266 arg1Of NM021822,GenBank™
R11396 T14268 T14265 arg3Of ),(
R11397 T14269 T14270 arg1Of We,cloned
R11398 T14273 T14270 arg2Of promoter,cloned
R11399 T14273 T14271 arg1Of promoter,a
R114 T141 T142 arg1Of region,of
R1140 T1353 T1347 arg1Of transcription,a
R11400 T14273 T14272 arg1Of promoter,1025 bp
R11401 T14273 T14274 arg1Of promoter,","
R11402 T14273 T14275 arg1Of promoter,which
R11403 T14273 T14276 arg1Of promoter,ranges
R11404 T14276 T14277 arg1Of ranges,from
R11405 T14278 T14277 arg2Of position,from
R11406 T14278 T14279 arg1Of position,−959/+66
R11407 T14278 T14281 arg1Of position,to
R11408 T14281 T14280 arg1Of to,relative
R11409 T14284 T14281 arg2Of TSS,to
R1141 T1353 T1348 arg1Of transcription,180 bp
R11410 T14284 T14282 arg1Of TSS,the
R11411 T14284 T14283 arg2Of TSS,identified
R11412 T14287 T14285 arg1Of assays,Luciferase
R11413 T14287 T14286 arg1Of assays,reporter
R11414 T14287 T14288 arg1Of assays,showed
R11415 T14291 T14290 arg1Of promoter,this
R11416 T14291 T14292 arg1Of promoter,was
R11417 T14291 T14294 arg1Of promoter,active
R11418 T14292 T14288 arg2Of was,showed
R11419 T14292 T14289 arg1Of was,that
R1142 T1353 T1349 arg1Of transcription,region
R11420 T14292 T14295 arg1Of was,in
R11421 T14294 T14292 arg2Of active,was
R11422 T14294 T14293 arg1Of active,transcriptionally
R11423 T14297 T14295 arg2Of cells,in
R11424 T14297 T14296 arg1Of cells,A3.01 T
R11425 T14298 T14299 arg1Of Treatment,with
R11426 T14298 T14304 arg1Of Treatment,did
R11427 T14298 T14307 arg1Of Treatment,enhance
R11428 T14303 T14299 arg2Of TPA,with
R11429 T14303 T14300 arg1Of TPA,the
R1143 T1353 T1350 arg1Of transcription,that
R11430 T14303 T14301 arg1Of TPA,phorbol
R11431 T14303 T14302 arg1Of TPA,ester
R11432 T14307 T14304 arg2Of enhance,did
R11433 T14307 T14305 arg1Of enhance,not
R11434 T14307 T14306 arg1Of enhance,further
R11435 T14307 T14310 arg1Of enhance,","
R11436 T14307 T14311 arg1Of enhance,although
R11437 T14309 T14307 arg2Of activity,enhance
R11438 T14309 T14308 arg1Of activity,transcriptional
R11439 T14312 T14313 arg1Of upregulation,of
R1144 T1353 T1351 arg2Of transcription,mediated
R11440 T14312 T14320 arg1Of upregulation,by
R11441 T14312 T14322 arg1Of upregulation,has
R11442 T14312 T14323 arg1Of upregulation,been
R11443 T14312 T14324 arg2Of upregulation,described
R11444 T14316 T14313 arg2Of levels,of
R11445 T14316 T14314 arg1Of levels,A3G
R11446 T14316 T14315 arg1Of levels,mRNA
R11447 T14316 T14317 arg1Of levels,in
R11448 T14319 T14317 arg2Of cells,in
R11449 T14319 T14318 arg1Of cells,T
R1145 T1353 T1352 arg1Of transcription,basal
R11450 T14321 T14320 arg2Of TPA,by
R11451 T14324 T14311 arg2Of described,although
R11452 T14324 T14322 arg2Of described,has
R11453 T14324 T14323 arg2Of described,been
R11454 T14324 T14325 arg1Of described,(
R11455 T14326 T14325 arg2Of 33,(
R11456 T14327 T14325 arg3Of ),(
R11457 T14330 T14328 arg1Of al.,Rose
R11458 T14330 T14329 arg1Of al.,et
R11459 T14330 T14331 arg1Of al.,used
R1146 T1356 T1354 arg2Of cells,In
R11460 T14330 T14335 arg1Of al.,block
R11461 T14330 T14339 arg1Of al.,did
R11462 T14330 T14341 arg1Of al.,find
R11463 T14333 T14331 arg2Of D,used
R11464 T14333 T14332 arg1Of D,actinomycin
R11465 T14335 T14338 arg1Of block,and
R11466 T14337 T14335 arg2Of transcription,block
R11467 T14337 T14336 arg1Of transcription,further
R11468 T14338 T14331 arg3Of and,used
R11469 T14338 T14334 arg1Of and,to
R1147 T1356 T1355 arg1Of cells,T
R11470 T14341 T14338 arg2Of find,and
R11471 T14341 T14339 arg2Of find,did
R11472 T14341 T14340 arg1Of find,not
R11473 T14342 T14341 arg2Of evidence,find
R11474 T14342 T14343 arg1Of evidence,for
R11475 T14346 T14343 arg2Of stability,for
R11476 T14346 T14344 arg2Of stability,enhanced
R11477 T14346 T14345 arg1Of stability,mRNA
R11478 T14350 T14349 arg1Of authors,the
R11479 T14350 T14351 arg1Of authors,suggested
R1148 T1359 T1358 arg1Of activity,transcriptional
R11480 T14351 T14347 arg1Of suggested,Therefore
R11481 T14351 T14348 arg1Of suggested,","
R11482 T14356 T14353 arg1Of rate,an
R11483 T14356 T14354 arg2Of rate,enhanced
R11484 T14356 T14355 arg1Of rate,transcription
R11485 T14356 T14357 arg1Of rate,could
R11486 T14356 T14358 arg1Of rate,be
R11487 T14356 T14359 arg1Of rate,responsible
R11488 T14358 T14351 arg2Of be,suggested
R11489 T14358 T14352 arg1Of be,that
R1149 T1359 T1360 arg1Of activity,of
R11490 T14358 T14357 arg2Of be,could
R11491 T14358 T14367 arg1Of be,after
R11492 T14359 T14358 arg2Of responsible,be
R11493 T14359 T14360 arg1Of responsible,for
R11494 T14363 T14360 arg2Of amount,for
R11495 T14363 T14361 arg1Of amount,the
R11496 T14363 T14362 arg2Of amount,increased
R11497 T14363 T14364 arg1Of amount,of
R11498 T14366 T14364 arg2Of mRNA,of
R11499 T14366 T14365 arg1Of mRNA,A3G
R115 T143 T142 arg2Of A3G,of
R1150 T1359 T1364 arg1Of activity,was
R11500 T14369 T14367 arg2Of treatment,after
R11501 T14369 T14368 arg1Of treatment,TPA
R11502 T14374 T14372 arg1Of analysis,the
R11503 T14374 T14373 arg1Of analysis,promoter
R11504 T14374 T14376 arg2Of analysis,performed
R11505 T14374 T14377 arg1Of analysis,indicates
R11506 T14375 T14376 arg1Of we,performed
R11507 T14377 T14370 arg1Of indicates,However
R11508 T14377 T14371 arg1Of indicates,","
R11509 T14380 T14377 arg2Of mechanism,indicates
R1151 T1359 T1366 arg1Of activity,inducible
R11510 T14380 T14378 arg1Of mechanism,a
R11511 T14380 T14379 arg1Of mechanism,different
R11512 T14380 T14381 arg1Of mechanism,that
R11513 T14380 T14382 arg1Of mechanism,is
R11514 T14380 T14383 arg1Of mechanism,independent
R11515 T14383 T14382 arg2Of independent,is
R11516 T14383 T14384 arg1Of independent,of
R11517 T14386 T14384 arg2Of regulation,of
R11518 T14386 T14385 arg1Of regulation,transcriptional
R11519 T14388 T14387 arg2Of addition,In
R1152 T1359 T1375 arg1Of activity,was
R11520 T14390 T14391 arg1Of we,observed
R11521 T14391 T14387 arg1Of observed,In
R11522 T14391 T14389 arg1Of observed,","
R11523 T14395 T14393 arg1Of promoter,the
R11524 T14395 T14394 arg1Of promoter,A3G
R11525 T14395 T14396 arg1Of promoter,was
R11526 T14395 T14398 arg1Of promoter,inducible
R11527 T14396 T14397 arg1Of was,not
R11528 T14396 T14407 arg1Of was,whereas
R11529 T14398 T14396 arg2Of inducible,was
R1153 T1359 T1376 arg1Of activity,dependent
R11530 T14398 T14399 arg1Of inducible,by
R11531 T14400 T14401 arg1Of IFN-α,or
R11532 T14401 T14399 arg2Of or,by
R11533 T14401 T14403 arg1Of or,in
R11534 T14402 T14401 arg2Of IFN-γ,or
R11535 T14405 T14403 arg2Of cells,in
R11536 T14405 T14404 arg1Of cells,A3.01 T
R11537 T14407 T14391 arg2Of whereas,observed
R11538 T14407 T14392 arg1Of whereas,that
R11539 T14407 T14406 arg1Of whereas,","
R1154 T1363 T1360 arg2Of promoter,of
R11540 T14413 T14408 arg2Of HepG2,in
R11541 T14413 T14409 arg1Of HepG2,the
R11542 T14413 T14410 arg1Of HepG2,hepatic
R11543 T14413 T14411 arg1Of HepG2,cell
R11544 T14413 T14412 arg1Of HepG2,line
R11545 T14417 T14415 arg1Of induction,a
R11546 T14417 T14416 arg1Of induction,moderate
R11547 T14417 T14418 arg1Of induction,was
R11548 T14417 T14419 arg2Of induction,measured
R11549 T14419 T14407 arg2Of measured,whereas
R1155 T1363 T1361 arg1Of promoter,this
R11550 T14419 T14408 arg1Of measured,in
R11551 T14419 T14414 arg1Of measured,","
R11552 T14419 T14418 arg2Of measured,was
R11553 T14420 T14421 arg1Of It,has
R11554 T14420 T14422 arg1Of It,been
R11555 T14420 T14423 arg2Of It,described
R11556 T14423 T14421 arg2Of described,has
R11557 T14423 T14422 arg2Of described,been
R11558 T14423 T14424 arg1Of described,previously
R11559 T14428 T14426 arg1Of expression,A3G
R1156 T1363 T1362 arg1Of promoter,core
R11560 T14428 T14427 arg1Of expression,gene
R11561 T14428 T14429 arg1Of expression,is
R11562 T14428 T14430 arg2Of expression,upregulated
R11563 T14430 T14423 arg3Of upregulated,described
R11564 T14430 T14425 arg1Of upregulated,that
R11565 T14430 T14429 arg2Of upregulated,is
R11566 T14432 T14430 arg1Of interferons,upregulated
R11567 T14432 T14431 arg2Of interferons,by
R11568 T14432 T14433 arg1Of interferons,in
R11569 T14434 T14435 arg1Of hepatocytes,and
R1157 T1364 T1365 arg1Of was,not
R11570 T14435 T14433 arg2Of and,in
R11571 T14435 T14437 arg1Of and,(
R11572 T14436 T14435 arg2Of macrophages,and
R11573 T14438 T14437 arg2Of 46–48,(
R11574 T14438 T14439 arg1Of 46–48,","
R11575 T14440 T14439 arg2Of 52,","
R11576 T14441 T14437 arg3Of ),(
R11577 T14444 T14442 arg2Of context,In
R11578 T14444 T14443 arg1Of context,this
R11579 T14448 T14446 arg1Of elements,two
R1158 T1364 T1374 arg1Of was,but
R11580 T14448 T14447 arg1Of elements,interferon-responsive
R11581 T14448 T14449 arg1Of elements,have
R11582 T14448 T14450 arg1Of elements,been
R11583 T14448 T14451 arg2Of elements,identified
R11584 T14451 T14442 arg1Of identified,In
R11585 T14451 T14445 arg1Of identified,","
R11586 T14451 T14449 arg2Of identified,have
R11587 T14451 T14450 arg2Of identified,been
R11588 T14451 T14452 arg1Of identified,at
R11589 T14455 T14456 arg1Of −6/+9,and
R1159 T1366 T1364 arg2Of inducible,was
R11590 T14456 T14452 arg2Of and,at
R11591 T14456 T14453 arg1Of and,the
R11592 T14456 T14454 arg1Of and,positions
R11593 T14456 T14458 arg1Of and,relative
R11594 T14457 T14456 arg2Of +1/+15,and
R11595 T14458 T14459 arg1Of relative,to
R11596 T14461 T14459 arg2Of TSS,to
R11597 T14461 T14460 arg1Of TSS,the
R11598 T14461 T14462 arg1Of TSS,(
R11599 T14463 T14462 arg2Of 48,(
R116 T146 T144 arg1Of sites,Transcriptional
R1160 T1366 T1367 arg1Of inducible,by
R11600 T14464 T14462 arg3Of ),(
R11601 T14465 T14466 arg1Of Consistent,with
R11602 T14468 T14466 arg2Of data,with
R11603 T14468 T14467 arg1Of data,this
R11604 T14470 T14471 arg1Of we,observed
R11605 T14471 T14465 arg1Of observed,Consistent
R11606 T14471 T14469 arg1Of observed,","
R11607 T14474 T14471 arg2Of induction,observed
R11608 T14474 T14472 arg1Of induction,an
R11609 T14474 T14473 arg1Of induction,interferon
R1161 T1369 T1368 arg1Of stimulation,mitogenic
R11610 T14474 T14475 arg1Of induction,in
R11611 T14476 T14475 arg2Of hepatocytes,in
R11612 T14476 T14477 arg1Of hepatocytes,for
R11613 T14479 T14477 arg2Of fragments,for
R11614 T14479 T14478 arg1Of fragments,the
R11615 T14479 T14480 arg1Of fragments,ranging
R11616 T14480 T14481 arg1Of ranging,between
R11617 T14482 T14483 arg1Of 1025,and
R11618 T14483 T14481 arg2Of and,between
R11619 T14485 T14483 arg2Of length,and
R1162 T1369 T1370 arg1Of stimulation,or
R11620 T14485 T14484 arg1Of length,120 bp
R11621 T14487 T14486 arg1Of activity,The
R11622 T14487 T14488 arg1Of activity,of
R11623 T14487 T14492 arg1Of activity,that
R11624 T14487 T14493 arg1Of activity,does
R11625 T14487 T14495 arg1Of activity,contain
R11626 T14487 T14498 arg1Of activity,was
R11627 T14487 T14500 arg2Of activity,affected
R11628 T14491 T14488 arg2Of fragment,of
R11629 T14491 T14489 arg1Of fragment,the
R1163 T1370 T1367 arg2Of or,by
R11630 T14491 T14490 arg1Of fragment,60 bp
R11631 T14495 T14493 arg2Of contain,does
R11632 T14495 T14494 arg1Of contain,not
R11633 T14497 T14495 arg2Of motifs,contain
R11634 T14497 T14496 arg1Of motifs,these
R11635 T14500 T14498 arg2Of affected,was
R11636 T14500 T14499 arg1Of affected,not
R11637 T14504 T14503 arg1Of induction,the
R11638 T14504 T14506 arg2Of induction,observed
R11639 T14504 T14507 arg1Of induction,was
R1164 T1372 T1370 arg2Of treatment,or
R11640 T14504 T14510 arg2Of induction,mediated
R11641 T14505 T14506 arg1Of we,observed
R11642 T14509 T14508 arg1Of likely,most
R11643 T14510 T14501 arg1Of mediated,Thus
R11644 T14510 T14502 arg1Of mediated,","
R11645 T14510 T14507 arg2Of mediated,was
R11646 T14510 T14509 arg1Of mediated,likely
R11647 T14515 T14510 arg1Of elements,mediated
R11648 T14515 T14511 arg2Of elements,by
R11649 T14515 T14512 arg1Of elements,the
R1165 T1372 T1371 arg1Of treatment,interferon
R11650 T14515 T14513 arg2Of elements,described
R11651 T14515 T14514 arg1Of elements,interferon-responsive
R11652 T14519 T14518 arg2Of to,according
R11653 T14521 T14519 arg2Of results,to
R11654 T14521 T14520 arg1Of results,our
R11655 T14524 T14523 arg1Of motifs,these
R11656 T14524 T14525 arg1Of motifs,can
R11657 T14524 T14526 arg1Of motifs,enhance
R11658 T14526 T14516 arg1Of enhance,However
R11659 T14526 T14517 arg1Of enhance,","
R1166 T1374 T1354 arg1Of but,In
R11660 T14526 T14518 arg1Of enhance,according
R11661 T14526 T14522 arg1Of enhance,","
R11662 T14526 T14525 arg2Of enhance,can
R11663 T14526 T14528 arg1Of enhance,in
R11664 T14526 T14534 arg1Of enhance,in
R11665 T14527 T14526 arg2Of transcription,enhance
R11666 T14528 T14532 arg1Of in,but
R11667 T14530 T14528 arg2Of cells,in
R11668 T14530 T14529 arg1Of cells,hepatic
R11669 T14532 T14531 arg1Of but,","
R1167 T1374 T1357 arg1Of but,","
R11670 T14534 T14532 arg2Of in,but
R11671 T14534 T14533 arg1Of in,not
R11672 T14536 T14534 arg2Of cells,in
R11673 T14536 T14535 arg1Of cells,T
R11674 T14537 T14538 arg1Of This,is
R11675 T14537 T14539 arg1Of This,surprising
R11676 T14538 T14540 arg1Of is,","
R11677 T14538 T14541 arg1Of is,since
R11678 T14538 T14550 arg1Of is,:
R11679 T14539 T14538 arg2Of surprising,is
R1168 T1374 T1373 arg1Of but,","
R11680 T14544 T14542 arg1Of cascades,IFN-α-inducible
R11681 T14544 T14543 arg1Of cascades,signaling
R11682 T14544 T14545 arg1Of cascades,are
R11683 T14544 T14546 arg1Of cascades,present
R11684 T14545 T14541 arg2Of are,since
R11685 T14546 T14545 arg2Of present,are
R11686 T14546 T14547 arg1Of present,in
R11687 T14549 T14547 arg2Of cells,in
R11688 T14549 T14548 arg1Of cells,A3.01 T
R11689 T14551 T14552 arg1Of we,showed
R1169 T1375 T1374 arg2Of was,but
R11690 T14552 T14550 arg2Of showed,:
R11691 T14556 T14554 arg1Of plasmid,the
R11692 T14556 T14555 arg1Of plasmid,control
R11693 T14556 T14557 arg1Of plasmid,harboring
R11694 T14556 T14561 arg1Of plasmid,was
R11695 T14556 T14563 arg2Of plasmid,induced
R11696 T14560 T14557 arg2Of elements,harboring
R11697 T14560 T14558 arg1Of elements,interferon-responsive
R11698 T14560 T14559 arg1Of elements,GAS
R11699 T14563 T14552 arg2Of induced,showed
R117 T146 T145 arg1Of sites,start
R1170 T1376 T1375 arg2Of dependent,was
R11700 T14563 T14553 arg1Of induced,that
R11701 T14563 T14561 arg2Of induced,was
R11702 T14563 T14562 arg1Of induced,markedly
R11703 T14566 T14563 arg1Of treatment,induced
R11704 T14566 T14564 arg2Of treatment,by
R11705 T14566 T14565 arg1Of treatment,IFN-α
R11706 T14568 T14567 arg2Of contrast,In
R11707 T14572 T14570 arg1Of element,the
R11708 T14572 T14571 arg1Of element,GAS
R11709 T14572 T14573 arg1Of element,was
R1171 T1376 T1377 arg1Of dependent,on
R11710 T14572 T14575 arg1Of element,responsive
R11711 T14573 T14567 arg1Of was,In
R11712 T14573 T14569 arg1Of was,","
R11713 T14573 T14574 arg1Of was,not
R11714 T14573 T14579 arg1Of was,in
R11715 T14573 T14582 arg1Of was,","
R11716 T14573 T14583 modOf was,suggesting
R11717 T14575 T14573 arg2Of responsive,was
R11718 T14575 T14576 arg1Of responsive,to
R11719 T14578 T14576 arg2Of treatment,to
R1172 T1379 T1377 arg2Of GC-box,on
R11720 T14578 T14577 arg1Of treatment,IFN-γ
R11721 T14581 T14579 arg2Of cells,in
R11722 T14581 T14580 arg1Of cells,these
R11723 T14588 T14585 arg1Of line,our
R11724 T14588 T14586 arg1Of line,T
R11725 T14588 T14587 arg1Of line,cell
R11726 T14588 T14589 arg1Of line,was
R11727 T14588 T14591 arg1Of line,able
R11728 T14588 T14593 arg1Of line,mediate
R11729 T14589 T14583 arg2Of was,suggesting
R1173 T1379 T1378 arg1Of GC-box,a
R11730 T14589 T14584 arg1Of was,that
R11731 T14589 T14590 arg1Of was,not
R11732 T14591 T14589 arg2Of able,was
R11733 T14593 T14591 arg2Of mediate,able
R11734 T14593 T14592 arg1Of mediate,to
R11735 T14595 T14593 arg2Of signals,mediate
R11736 T14595 T14594 arg1Of signals,IFN-γ-induced
R11737 T14597 T14596 arg1Of far,So
R11738 T14602 T14599 arg2Of activity,enhanced
R11739 T14602 T14600 arg1Of activity,A3G
R1174 T1379 T1380 arg1Of GC-box,which
R11740 T14602 T14601 arg1Of activity,promoter
R11741 T14602 T14603 arg1Of activity,by
R11742 T14602 T14605 arg1Of activity,is
R11743 T14602 T14607 arg2Of activity,described
R11744 T14604 T14603 arg2Of interferons,by
R11745 T14607 T14605 arg2Of described,is
R11746 T14607 T14606 arg1Of described,clearly
R11747 T14607 T14608 arg1Of described,in
R11748 T14607 T14613 arg1Of described,whereas
R11749 T14609 T14610 arg1Of hepatocytes,and
R1175 T1379 T1381 arg1Of GC-box,was
R11750 T14610 T14608 arg2Of and,in
R11751 T14611 T14610 arg2Of macrophages,and
R11752 T14613 T14597 arg1Of whereas,far
R11753 T14613 T14598 arg1Of whereas,","
R11754 T14613 T14612 arg1Of whereas,","
R11755 T14615 T14614 arg1Of situation,the
R11756 T14615 T14616 arg1Of situation,in
R11757 T14615 T14619 arg1Of situation,is
R11758 T14615 T14621 arg1Of situation,unclear
R11759 T14618 T14616 arg2Of cells,in
R1176 T1379 T1382 arg2Of GC-box,recognized
R11760 T14618 T14617 arg1Of cells,T
R11761 T14619 T14613 arg2Of is,whereas
R11762 T14619 T14620 arg1Of is,still
R11763 T14621 T14619 arg2Of unclear,is
R11764 T14624 T14622 arg1Of study,A
R11765 T14624 T14623 arg1Of study,recent
R11766 T14624 T14625 arg1Of study,found
R11767 T14627 T14625 arg2Of influence,found
R11768 T14627 T14626 arg1Of influence,no
R11769 T14627 T14628 arg1Of influence,of
R1177 T1382 T1381 arg2Of recognized,was
R11770 T14627 T14632 arg1Of influence,on
R11771 T14629 T14630 arg1Of IFN-α,or
R11772 T14630 T14628 arg2Of or,of
R11773 T14631 T14630 arg2Of IFN-γ,or
R11774 T14634 T14632 arg2Of expression,on
R11775 T14634 T14633 arg1Of expression,A3G
R11776 T14634 T14635 arg1Of expression,in
R11777 T14639 T14635 arg2Of lymphocytes,in
R11778 T14639 T14636 arg1Of lymphocytes,resting
R11779 T14639 T14637 arg1Of lymphocytes,primary
R1178 T1387 T1385 arg2Of protein,(
R11780 T14639 T14638 arg1Of lymphocytes,blood
R11781 T14639 T14640 arg1Of lymphocytes,(
R11782 T14641 T14640 arg2Of 52,(
R11783 T14642 T14640 arg3Of ),(
R11784 T14644 T14643 arg1Of publication,Another
R11785 T14644 T14645 arg1Of publication,describes
R11786 T14645 T14651 arg1Of describes,after
R11787 T14645 T14662 arg1Of describes,in
R11788 T14648 T14645 arg2Of expression,describes
R11789 T14648 T14646 arg1Of expression,an
R1179 T1387 T1386 arg1Of protein,specificity
R11790 T14648 T14647 arg2Of expression,enhanced
R11791 T14648 T14649 arg1Of expression,of
R11792 T14650 T14649 arg2Of A3G,of
R11793 T14651 T14660 arg1Of after,but
R11794 T14653 T14651 arg2Of treatment,after
R11795 T14653 T14652 arg1Of treatment,IFN-α
R11796 T14653 T14654 arg1Of treatment,in
R11797 T14658 T14654 arg2Of cells,in
R11798 T14658 T14655 arg1Of cells,resting
R11799 T14658 T14656 arg1Of cells,primary
R118 T146 T147 arg1Of sites,were
R1180 T1388 T1385 arg3Of ),(
R11800 T14658 T14657 arg1Of cells,CD4 T
R11801 T14660 T14659 arg1Of but,","
R11802 T14662 T14660 arg2Of in,but
R11803 T14662 T14661 arg1Of in,not
R11804 T14665 T14662 arg2Of cells,in
R11805 T14665 T14663 arg2Of cells,activated
R11806 T14665 T14664 arg1Of cells,T
R11807 T14665 T14666 arg1Of cells,(
R11808 T14667 T14666 arg2Of 53,(
R11809 T14668 T14666 arg3Of ),(
R1181 T1389 T1390 arg1Of 1,and
R11810 T14670 T14669 arg1Of observation,This
R11811 T14670 T14671 arg1Of observation,is
R11812 T14670 T14673 arg1Of observation,contradictory
R11813 T14671 T14672 arg1Of is,not
R11814 T14671 T14677 arg1Of is,since
R11815 T14673 T14671 arg2Of contradictory,is
R11816 T14673 T14674 arg1Of contradictory,to
R11817 T14676 T14674 arg2Of results,to
R11818 T14676 T14675 arg1Of results,our
R11819 T14680 T14678 arg1Of lines,T
R1182 T1391 T1390 arg2Of Sp3,and
R11820 T14680 T14679 arg1Of lines,cell
R11821 T14680 T14681 arg1Of lines,are
R11822 T14680 T14683 arg1Of lines,active
R11823 T14681 T14677 arg2Of are,since
R11824 T14683 T14681 arg2Of active,are
R11825 T14683 T14682 arg1Of active,mitotically
R11826 T14683 T14684 arg1Of active,and
R11827 T14683 T14686 arg1Of active,rather
R11828 T14683 T14687 arg1Of active,in
R11829 T14683 T14690 arg1Of active,than
R1183 T1393 T1382 arg1Of factors,recognized
R11830 T14686 T14685 arg1Of rather,therefore
R11831 T14689 T14687 arg2Of activated,in
R11832 T14689 T14688 arg1Of activated,an
R11833 T14691 T14690 arg2Of in,than
R11834 T14694 T14691 arg2Of state,in
R11835 T14694 T14692 arg1Of state,a
R11836 T14694 T14693 arg1Of state,resting
R11837 T14696 T14695 arg2Of conclusion,In
R11838 T14700 T14698 arg1Of data,the
R11839 T14700 T14699 arg1Of data,current
R1184 T1393 T1383 arg2Of factors,by
R11840 T14700 T14701 arg1Of data,suggests
R11841 T14701 T14695 arg1Of suggests,In
R11842 T14701 T14697 arg1Of suggests,","
R11843 T14703 T14704 arg1Of regulation,of
R11844 T14703 T14709 arg1Of regulation,by
R11845 T14703 T14711 arg1Of regulation,is
R11846 T14703 T14712 arg1Of regulation,dependent
R11847 T14708 T14704 arg2Of activity,of
R11848 T14708 T14705 arg1Of activity,the
R11849 T14708 T14706 arg1Of activity,A3G
R1185 T1393 T1384 arg1Of factors,Sp
R11850 T14708 T14707 arg1Of activity,promoter
R11851 T14710 T14709 arg2Of interferons,by
R11852 T14711 T14701 arg2Of is,suggests
R11853 T14711 T14702 arg1Of is,that
R11854 T14712 T14711 arg2Of dependent,is
R11855 T14712 T14713 arg1Of dependent,on
R11856 T14712 T14719 arg1Of dependent,also
R11857 T14712 T14720 arg1Of dependent,from
R11858 T14713 T14717 arg1Of on,and
R11859 T14716 T14713 arg2Of type,on
R1186 T1393 T1385 arg1Of factors,(
R11860 T14716 T14714 arg1Of type,the
R11861 T14716 T14715 arg1Of type,cell
R11862 T14719 T14717 arg2Of also,and
R11863 T14719 T14718 arg1Of also,possibly
R11864 T14724 T14720 arg2Of status,from
R11865 T14724 T14721 arg1Of status,the
R11866 T14724 T14722 arg1Of status,cellular
R11867 T14724 T14723 arg1Of status,activation
R11868 T14725 T14727 arg1Of We,analyzed
R11869 T14727 T14726 arg1Of analyzed,additionally
R1187 T1393 T1389 arg1Of factors,1
R11870 T14729 T14727 arg2Of influence,analyzed
R11871 T14729 T14728 arg1Of influence,the
R11872 T14729 T14730 arg1Of influence,of
R11873 T14729 T14733 arg1Of influence,on
R11874 T14732 T14730 arg2Of proteins,of
R11875 T14732 T14731 arg1Of proteins,HIV-1
R11876 T14736 T14733 arg2Of activity,on
R11877 T14736 T14734 arg1Of activity,A3G
R11878 T14736 T14735 arg1Of activity,promoter
R11879 T14740 T14737 arg1Of protein,The
R1188 T1393 T1391 arg1Of factors,Sp3
R11880 T14740 T14738 arg1Of protein,HIV-1
R11881 T14740 T14739 arg1Of protein,Vif
R11882 T14740 T14741 arg1Of protein,is
R11883 T14740 T14742 arg1Of protein,neutralizing
R11884 T14742 T14741 arg2Of neutralizing,is
R11885 T14742 T14748 arg1Of neutralizing,by
R11886 T14745 T14742 arg2Of function,neutralizing
R11887 T14745 T14743 arg1Of function,the
R11888 T14745 T14744 arg1Of function,antiviral
R11889 T14745 T14746 arg1Of function,of
R1189 T1393 T1392 arg1Of factors,transcription
R11890 T14747 T14746 arg2Of A3G,of
R11891 T14750 T14748 arg2Of multitude,by
R11892 T14750 T14749 arg1Of multitude,a
R11893 T14750 T14751 arg1Of multitude,of
R11894 T14752 T14751 arg2Of ways,of
R11895 T14753 T14760 arg1Of Targeting,is
R11896 T14753 T14761 arg2Of Targeting,considered
R11897 T14753 T14763 arg1Of Targeting,be
R11898 T14756 T14753 arg2Of protein,Targeting
R11899 T14756 T14754 arg1Of protein,the
R119 T146 T148 arg2Of sites,identified
R11900 T14756 T14755 arg1Of protein,A3G
R11901 T14756 T14757 arg1Of protein,for
R11902 T14759 T14757 arg2Of degradation,for
R11903 T14759 T14758 arg1Of degradation,proteasomal
R11904 T14761 T14760 arg2Of considered,is
R11905 T14761 T14773 arg1Of considered,but
R11906 T14763 T14761 arg3Of be,considered
R11907 T14763 T14762 arg1Of be,to
R11908 T14766 T14763 arg2Of mode,be
R11909 T14766 T14764 arg1Of mode,the
R11910 T14766 T14765 arg1Of mode,main
R11911 T14766 T14767 arg1Of mode,of
R11912 T14768 T14767 arg2Of action,of
R11913 T14768 T14769 arg1Of action,(
R11914 T14770 T14769 arg2Of 37–41,(
R11915 T14771 T14769 arg3Of ),(
R11916 T14773 T14772 arg1Of but,","
R11917 T14774 T14775 arg1Of it,becomes
R11918 T14774 T14776 arg1Of it,more
R11919 T14774 T14779 arg1Of it,clear
R11920 T14775 T14773 arg2Of becomes,but
R11921 T14776 T14777 arg1Of more,and
R11922 T14777 T14775 arg2Of and,becomes
R11923 T14779 T14777 arg2Of clear,and
R11924 T14779 T14778 arg1Of clear,more
R11925 T14782 T14781 arg1Of mechanisms,other
R11926 T14782 T14783 arg1Of mechanisms,are
R11927 T14782 T14785 arg2Of mechanisms,involved
R11928 T14785 T14779 arg2Of involved,clear
R11929 T14785 T14780 arg1Of involved,that
R11930 T14785 T14783 arg2Of involved,are
R11931 T14785 T14784 arg1Of involved,also
R11932 T14786 T14787 arg1Of There,is
R11933 T14788 T14787 arg2Of evidence,is
R11934 T14790 T14792 arg1Of Vif,promotes
R11935 T14792 T14791 arg1Of promotes,also
R11936 T14792 T14800 arg1Of promotes,and
R11937 T14793 T14792 arg2Of exclusion,promotes
R11938 T14793 T14794 arg1Of exclusion,of
R11939 T14793 T14796 arg1Of exclusion,from
R11940 T14795 T14794 arg2Of A3G,of
R11941 T14799 T14796 arg2Of particles,from
R11942 T14799 T14797 arg1Of particles,the
R11943 T14799 T14798 arg1Of particles,virus
R11944 T14800 T14788 arg2Of and,evidence
R11945 T14800 T14789 arg1Of and,that
R11946 T14802 T14801 arg1Of influence,an
R11947 T14802 T14803 arg1Of influence,on
R11948 T14802 T14808 arg1Of influence,is
R11949 T14802 T14809 arg2Of influence,discussed
R11950 T14807 T14803 arg2Of process,on
R11951 T14807 T14804 arg1Of process,the
R11952 T14807 T14805 arg1Of process,A3G
R11953 T14807 T14806 arg1Of process,translation
R11954 T14809 T14800 arg2Of discussed,and
R11955 T14809 T14808 arg2Of discussed,is
R11956 T14809 T14810 arg1Of discussed,(
R11957 T14811 T14810 arg2Of "8,42,43",(
R11958 T14812 T14810 arg3Of ),(
R11959 T14814 T14813 arg1Of question,The
R11960 T14814 T14824 arg1Of question,has
R11961 T14814 T14826 arg1Of question,been
R11962 T14814 T14827 arg2Of question,analyzed
R11963 T14816 T14817 arg1Of Vif,alters
R11964 T14817 T14814 arg2Of alters,question
R11965 T14817 T14815 arg1Of alters,whether
R11966 T14818 T14817 arg2Of transcription,alters
R11967 T14818 T14819 arg2Of transcription,controlled
R11968 T14823 T14819 arg1Of promoter,controlled
R11969 T14823 T14820 arg2Of promoter,by
R11970 T14823 T14821 arg1Of promoter,the
R11971 T14823 T14822 arg1Of promoter,A3G
R11972 T14827 T14824 arg2Of analyzed,has
R11973 T14827 T14825 arg1Of analyzed,not
R11974 T14827 T14826 arg2Of analyzed,been
R11975 T14827 T14829 arg1Of analyzed,far
R11976 T14829 T14828 arg1Of far,so
R11977 T14831 T14830 arg1Of analysis,Our
R11978 T14831 T14832 arg1Of analysis,indicates
R11979 T14834 T14835 arg1Of transcription,from
R11980 T14834 T14839 arg1Of transcription,is
R11981 T14834 T14840 arg1Of transcription,unaffected
R11982 T14838 T14835 arg2Of promoter,from
R11983 T14838 T14836 arg1Of promoter,the
R11984 T14838 T14837 arg1Of promoter,A3G
R11985 T14839 T14832 arg2Of is,indicates
R11986 T14839 T14833 arg1Of is,that
R11987 T14840 T14839 arg2Of unaffected,is
R11988 T14840 T14841 arg1Of unaffected,by
R11989 T14842 T14843 arg1Of Vif,or
R11990 T14843 T14841 arg2Of or,by
R11991 T14846 T14843 arg2Of proteins,or
R11992 T14846 T14844 arg1Of proteins,other
R11993 T14846 T14845 arg1Of proteins,HIV-1
R11994 T14847 T14848 arg1Of Taken,together
R11995 T14853 T14850 arg2Of lines,in
R11996 T14853 T14851 arg1Of lines,T
R11997 T14853 T14852 arg1Of lines,cell
R11998 T14857 T14855 arg1Of promoter,the
R11999 T14857 T14856 arg1Of promoter,A3G
R120 T148 T147 arg2Of identified,were
R12000 T14857 T14858 arg1Of promoter,appears
R12001 T14857 T14860 arg1Of promoter,active
R12002 T14858 T14847 modOf appears,Taken
R12003 T14858 T14849 arg1Of appears,","
R12004 T14858 T14850 arg1Of appears,in
R12005 T14858 T14854 arg1Of appears,","
R12006 T14860 T14858 arg2Of active,appears
R12007 T14860 T14859 arg1Of active,constitutively
R12008 T14862 T14861 arg2Of generating,By
R12009 T14864 T14862 arg2Of series,generating
R12010 T14864 T14863 arg1Of series,a
R12011 T14864 T14865 arg1Of series,of
R12012 T14867 T14865 arg2Of deletions,of
R12013 T14867 T14866 arg1Of deletions,5′
R12014 T14869 T14862 arg1Of we,generating
R12015 T14869 T14870 arg1Of we,showed
R12016 T14870 T14861 arg1Of showed,By
R12017 T14870 T14868 arg1Of showed,","
R12018 T14874 T14872 arg1Of promoter,the
R12019 T14874 T14873 arg1Of promoter,core
R12020 T14874 T14875 arg1Of promoter,is
R12021 T14874 T14876 arg1Of promoter,located
R12022 T14875 T14870 arg2Of is,showed
R12023 T14875 T14871 arg1Of is,that
R12024 T14876 T14875 arg2Of located,is
R12025 T14876 T14877 arg1Of located,within
R12026 T14879 T14877 arg2Of region,within
R12027 T14879 T14878 arg1Of region,the
R12028 T14879 T14880 arg1Of region,−114/+66
R12029 T14879 T14882 arg1Of region,to
R12030 T14882 T14881 arg1Of to,relative
R12031 T14884 T14882 arg2Of TSS,to
R12032 T14884 T14883 arg1Of TSS,the
R12033 T14887 T14885 arg1Of promoter,This
R12034 T14887 T14886 arg1Of promoter,180 bp
R12035 T14887 T14888 arg1Of promoter,was
R12036 T14887 T14890 arg1Of promoter,active
R12037 T14888 T14902 arg1Of was,","
R12038 T14888 T14903 modOf was,indicating
R12039 T14890 T14888 arg2Of active,was
R12040 T14890 T14889 arg1Of active,transcriptionally
R12041 T14890 T14891 arg1Of active,in
R12042 T14893 T14894 arg1Of lymphoid,","
R12043 T14894 T14896 arg1Of ",",and
R12044 T14895 T14894 arg2Of myeloid,","
R12045 T14897 T14896 arg2Of hepatic,and
R12046 T14899 T14891 arg2Of lines,in
R12047 T14899 T14892 arg1Of lines,the
R12048 T14899 T14893 arg1Of lines,lymphoid
R12049 T14899 T14895 arg1Of lines,myeloid
R12050 T14899 T14897 arg1Of lines,hepatic
R12051 T14899 T14898 arg1Of lines,cell
R12052 T14899 T14901 arg2Of lines,tested
R12053 T14900 T14901 arg1Of we,tested
R12054 T14907 T14905 arg1Of factors,ubiquitous
R12055 T14907 T14906 arg1Of factors,transcription
R12056 T14907 T14908 arg1Of factors,are
R12057 T14907 T14909 arg2Of factors,involved
R12058 T14909 T14903 arg2Of involved,indicating
R12059 T14909 T14904 arg1Of involved,that
R12060 T14909 T14908 arg2Of involved,are
R12061 T14909 T14910 arg1Of involved,in
R12062 T14911 T14910 arg2Of regulation,in
R12063 T14911 T14912 arg1Of regulation,of
R12064 T14915 T14912 arg2Of transcription,of
R12065 T14915 T14913 arg1Of transcription,A3G
R12066 T14915 T14914 arg1Of transcription,gene
R12067 T14917 T14916 arg1Of GC-box,A
R12068 T14917 T14918 arg1Of GC-box,with
R12069 T14917 T14922 arg1Of GC-box,was
R12070 T14917 T14923 arg2Of GC-box,identified
R12071 T14921 T14918 arg2Of TGGGCGGGAC,with
R12072 T14921 T14919 arg1Of TGGGCGGGAC,the
R12073 T14921 T14920 arg1Of TGGGCGGGAC,sequence
R12074 T14923 T14922 arg2Of identified,was
R12075 T14923 T14924 arg1Of identified,at
R12076 T14925 T14924 arg2Of position,at
R12077 T14925 T14926 arg1Of position,−87/−78
R12078 T14925 T14927 arg1Of position,of
R12079 T14930 T14927 arg2Of promoter,of
R12080 T14930 T14928 arg1Of promoter,the
R12081 T14930 T14929 arg1Of promoter,A3G
R12082 T14932 T14931 arg1Of GC-box,This
R12083 T14932 T14933 arg1Of GC-box,is
R12084 T14932 T14934 arg1Of GC-box,essential
R12085 T14933 T14939 arg1Of is,","
R12086 T14933 T14940 arg1Of is,since
R12087 T14934 T14933 arg2Of essential,is
R12088 T14934 T14935 arg1Of essential,for
R12089 T14938 T14935 arg2Of activity,for
R12090 T14938 T14936 arg1Of activity,basal
R12091 T14938 T14937 arg1Of activity,promoter
R12092 T14941 T14944 arg1Of changing,to
R12093 T14941 T14946 arg1Of changing,by
R12094 T14941 T14952 arg1Of changing,reduced
R12095 T14943 T14941 arg2Of motif,changing
R12096 T14943 T14942 arg1Of motif,the
R12097 T14945 T14944 arg2Of TGTTCGGGAC,to
R12098 T14947 T14946 arg2Of introducing,by
R12099 T14950 T14947 arg2Of mutations,introducing
R121 T151 T148 arg1Of amplification,identified
R12100 T14950 T14948 arg1Of mutations,two
R12101 T14950 T14949 arg1Of mutations,point
R12102 T14952 T14940 arg2Of reduced,since
R12103 T14952 T14951 arg1Of reduced,strongly
R12104 T14955 T14952 arg2Of activity,reduced
R12105 T14955 T14953 arg1Of activity,A3G
R12106 T14955 T14954 arg1Of activity,promoter
R12107 T14958 T14956 arg1Of potency,The
R12108 T14958 T14957 arg1Of potency,transcriptional
R12109 T14958 T14959 arg1Of potency,of
R12110 T14958 T14962 arg1Of potency,was
R12111 T14958 T14964 arg2Of potency,demonstrated
R12112 T14961 T14959 arg2Of GC-box,of
R12113 T14961 T14960 arg1Of GC-box,the
R12114 T14964 T14962 arg2Of demonstrated,was
R12115 T14964 T14963 arg1Of demonstrated,further
R12116 T14964 T14965 arg1Of demonstrated,by
R12117 T14966 T14965 arg2Of cloning,by
R12118 T14966 T14968 arg1Of cloning,upstream
R12119 T14967 T14966 arg2Of it,cloning
R12120 T14968 T14969 arg1Of upstream,of
R12121 T14972 T14969 arg2Of promoter,of
R12122 T14972 T14970 arg1Of promoter,an
R12123 T14972 T14971 arg1Of promoter,SV40
R12124 T14973 T14974 arg1Of This,resulted
R12125 T14974 T14975 arg1Of resulted,in
R12126 T14978 T14977 arg1Of enhanced,4-fold
R12127 T14980 T14975 arg2Of rate,in
R12128 T14980 T14976 arg1Of rate,a
R12129 T14980 T14978 arg1Of rate,enhanced
R12130 T14980 T14979 arg1Of rate,transcription
R12131 T14982 T14981 arg1Of hypothesis,The
R12132 T14982 T14995 arg1Of hypothesis,was
R12133 T14982 T14996 arg2Of hypothesis,confirmed
R12134 T14987 T14984 arg1Of factor,a
R12135 T14987 T14985 arg1Of factor,general
R12136 T14987 T14986 arg1Of factor,transcription
R12137 T14987 T14988 arg1Of factor,is
R12138 T14987 T14989 arg2Of factor,involved
R12139 T14989 T14982 arg2Of involved,hypothesis
R12140 T14989 T14983 arg1Of involved,that
R12141 T14989 T14988 arg2Of involved,is
R12142 T14989 T14990 arg1Of involved,in
R12143 T14991 T14990 arg2Of regulation,in
R12144 T14991 T14992 arg1Of regulation,of
R12145 T14994 T14992 arg2Of transcription,of
R12146 T14994 T14993 arg1Of transcription,A3G
R12147 T14996 T14995 arg2Of confirmed,was
R12148 T14998 T14996 arg1Of EMSA,confirmed
R12149 T14998 T14997 arg2Of EMSA,by
R12150 T15000 T14999 arg1Of analysis,Supershift
R12151 T15000 T15001 arg1Of analysis,showed
R12152 T15005 T15004 arg1Of factors,transcription
R12153 T15006 T15007 arg1Of Sp1,and
R12154 T15007 T15003 arg1Of and,the
R12155 T15007 T15005 arg1Of and,factors
R12156 T15007 T15009 arg1Of and,which
R12157 T15007 T15010 arg1Of and,are
R12158 T15007 T15012 arg2Of and,expressed
R12159 T15007 T15017 arg1Of and,bind
R12160 T15008 T15007 arg2Of Sp3,and
R12161 T15012 T15010 arg2Of expressed,are
R12162 T15012 T15011 arg1Of expressed,ubiquitously
R12163 T15012 T15013 arg1Of expressed,in
R12164 T15015 T15013 arg2Of cells,in
R12165 T15015 T15014 arg1Of cells,mammalian
R12166 T15017 T15001 arg2Of bind,showed
R12167 T15017 T15002 arg1Of bind,that
R12168 T15017 T15016 arg1Of bind,","
R12169 T15017 T15018 arg1Of bind,specifically
R12170 T15017 T15019 arg1Of bind,to
R12171 T15022 T15019 arg2Of motif,to
R12172 T15022 T15020 arg1Of motif,the
R12173 T15022 T15021 arg2Of motif,identified
R12174 T15024 T15023 arg2Of addition,In
R12175 T15027 T15026 arg1Of binding,the
R12176 T15027 T15028 arg1Of binding,of
R12177 T15027 T15032 arg1Of binding,to
R12178 T15027 T15037 arg1Of binding,was
R12179 T15027 T15038 arg2Of binding,demonstrated
R12180 T15029 T15030 arg1Of Sp1,and
R12181 T15030 T15028 arg2Of and,of
R12182 T15031 T15030 arg2Of Sp3,and
R12183 T15036 T15032 arg2Of promoter,to
R12184 T15036 T15033 arg1Of promoter,the
R12185 T15036 T15034 arg1Of promoter,endogenous
R12186 T15036 T15035 arg1Of promoter,A3G
R12187 T15038 T15023 arg1Of demonstrated,In
R12188 T15038 T15025 arg1Of demonstrated,","
R12189 T15038 T15037 arg2Of demonstrated,was
R12190 T15043 T15038 arg1Of assay,demonstrated
R12191 T15043 T15039 arg2Of assay,by
R12192 T15043 T15040 arg1Of assay,a
R12193 T15043 T15041 arg1Of assay,chromatin
R12194 T15043 T15042 arg1Of assay,immunoprecipitation
R12195 T15045 T15044 arg1Of observation,This
R12196 T15045 T15046 arg1Of observation,is
R12197 T15045 T15047 arg1Of observation,consistent
R12198 T15046 T15054 arg1Of is,","
R12199 T15046 T15055 arg1Of is,since
R122 T151 T149 arg2Of amplification,by
R12200 T15047 T15046 arg2Of consistent,is
R12201 T15047 T15048 arg1Of consistent,with
R12202 T15050 T15048 arg2Of results,with
R12203 T15050 T15049 arg1Of results,the
R12204 T15050 T15051 arg1Of results,of
R12205 T15053 T15051 arg2Of 5′-RACE,of
R12206 T15053 T15052 arg1Of 5′-RACE,the
R12207 T15056 T15057 arg1Of Sp1,is
R12208 T15056 T15058 arg2Of Sp1,known
R12209 T15056 T15060 arg1Of Sp1,play
R12210 T15056 T15079 arg1Of Sp1,is
R12211 T15056 T15080 arg2Of Sp1,associated
R12212 T15058 T15057 arg2Of known,is
R12213 T15058 T15078 arg1Of known,and
R12214 T15060 T15058 arg3Of play,known
R12215 T15060 T15059 arg1Of play,to
R12216 T15063 T15060 arg2Of role,play
R12217 T15063 T15061 arg1Of role,an
R12218 T15063 T15062 arg1Of role,important
R12219 T15063 T15064 arg1Of role,for
R12220 T15066 T15064 arg2Of polymerase,for
R12221 T15066 T15065 arg1Of polymerase,RNA
R12222 T15066 T15067 arg1Of polymerase,II
R12223 T15066 T15068 modOf polymerase,to
R12224 T15069 T15068 arg1Of bind,to
R12225 T15069 T15070 arg1Of bind,to
R12226 T15069 T15075 arg1Of bind,in
R12227 T15074 T15070 arg2Of site,to
R12228 T15074 T15071 arg1Of site,the
R12229 T15074 T15072 arg1Of site,transcription
R12230 T15074 T15073 arg1Of site,initiation
R12231 T15077 T15075 arg2Of promoters,in
R12232 T15077 T15076 arg1Of promoters,TATA-boxless
R12233 T15078 T15055 arg2Of and,since
R12234 T15080 T15078 arg2Of associated,and
R12235 T15080 T15079 arg2Of associated,is
R12236 T15080 T15081 arg1Of associated,with
R12237 T15085 T15081 arg2Of sites,with
R12238 T15085 T15082 arg1Of sites,multiple
R12239 T15085 T15083 arg1Of sites,transcription
R12240 T15085 T15084 arg1Of sites,initiation
R12241 T15085 T15086 arg1Of sites,(
R12242 T15087 T15086 arg2Of 54–56,(
R12243 T15088 T15086 arg3Of ),(
R12244 T15089 T15091 arg1Of We,tested
R12245 T15091 T15090 arg1Of tested,also
R12246 T15093 T15094 arg1Of overexpression,of
R12247 T15093 T15099 arg1Of overexpression,had
R12248 T15095 T15096 arg1Of Sp1,or
R12249 T15097 T15096 arg2Of Sp3,or
R12250 T15098 T15094 arg2Of proteins,of
R12251 T15098 T15095 arg1Of proteins,Sp1
R12252 T15098 T15097 arg1Of proteins,Sp3
R12253 T15099 T15091 arg2Of had,tested
R12254 T15099 T15092 arg1Of had,whether
R12255 T15099 T15102 arg1Of had,on
R12256 T15101 T15099 arg2Of influence,had
R12257 T15101 T15100 arg1Of influence,an
R12258 T15105 T15102 arg2Of activity,on
R12259 T15105 T15103 arg1Of activity,A3G
R12260 T15105 T15104 arg1Of activity,promoter
R12261 T15107 T15106 arg1Of assays,Luciferase
R12262 T15107 T15108 arg1Of assays,revealed
R12263 T15112 T15110 arg1Of activities,A3G
R12264 T15112 T15111 arg1Of activities,promoter
R12265 T15112 T15113 arg1Of activities,remained
R12266 T15112 T15114 arg1Of activities,unchanged
R12267 T15113 T15108 arg2Of remained,revealed
R12268 T15113 T15109 arg1Of remained,that
R12269 T15113 T15120 arg1Of remained,","
R12270 T15113 T15124 arg1Of remained,to
R12271 T15114 T15113 arg2Of unchanged,remained
R12272 T15114 T15115 arg1Of unchanged,(
R12273 T15116 T15115 arg2Of data,(
R12274 T15116 T15118 arg2Of data,shown
R12275 T15118 T15117 arg1Of shown,not
R12276 T15119 T15115 arg3Of ),(
R12277 T15122 T15121 arg1Of probably,most
R12278 T15124 T15122 arg1Of to,probably
R12279 T15124 T15123 arg1Of to,due
R12280 T15129 T15124 arg2Of level,to
R12281 T15129 T15125 arg1Of level,the
R12282 T15129 T15126 arg1Of level,high
R12283 T15129 T15127 arg1Of level,basal
R12284 T15129 T15128 arg1Of level,expression
R12285 T15129 T15130 arg1Of level,of
R12286 T15133 T15134 arg1Of Sp1,and/or
R12287 T15135 T15134 arg2Of Sp3,and/or
R12288 T15136 T15130 arg2Of proteins,of
R12289 T15136 T15131 arg1Of proteins,the
R12290 T15136 T15132 arg1Of proteins,endogenous
R12291 T15136 T15133 arg1Of proteins,Sp1
R12292 T15136 T15135 arg1Of proteins,Sp3
R12293 T15139 T15137 arg1Of family,The
R12294 T15139 T15138 arg1Of family,Sp
R12295 T15139 T15140 arg1Of family,of
R12296 T15139 T15143 arg1Of family,is
R12297 T15139 T15144 arg2Of family,involved
R12298 T15142 T15140 arg2Of factors,of
R12299 T15142 T15141 arg1Of factors,transcription
R123 T151 T150 arg1Of amplification,5′-rapid
R12300 T15144 T15143 arg2Of involved,is
R12301 T15144 T15145 arg1Of involved,in
R12302 T15147 T15145 arg2Of regulation,in
R12303 T15147 T15146 arg1Of regulation,transcriptional
R12304 T15147 T15148 arg1Of regulation,of
R12305 T15147 T15151 arg1Of regulation,","
R12306 T15150 T15148 arg2Of housekeeping,of
R12307 T15150 T15149 arg1Of housekeeping,many
R12308 T15152 T15153 arg1Of tissue-specific,","
R12309 T15153 T15155 arg1Of ",",and
R12310 T15154 T15153 arg2Of viral,","
R12311 T15156 T15155 arg2Of inducible,and
R12312 T15157 T15151 arg2Of genes,","
R12313 T15157 T15152 arg1Of genes,tissue-specific
R12314 T15157 T15154 arg1Of genes,viral
R12315 T15157 T15156 arg1Of genes,inducible
R12316 T15157 T15158 arg1Of genes,(
R12317 T15159 T15158 arg2Of 57,(
R12318 T15160 T15158 arg3Of ),(
R12319 T15162 T15164 arg1Of Sp1,acts
R12320 T15164 T15161 arg2Of acts,Whereas
R12321 T15164 T15163 arg1Of acts,typically
R12322 T15164 T15165 arg1Of acts,as
R12323 T15167 T15165 arg2Of activator,as
R12324 T15167 T15166 arg1Of activator,an
R12325 T15169 T15170 arg1Of Sp3,can
R12326 T15169 T15171 arg1Of Sp3,serve
R12327 T15171 T15161 arg1Of serve,Whereas
R12328 T15171 T15168 arg1Of serve,","
R12329 T15171 T15170 arg2Of serve,can
R12330 T15171 T15172 arg1Of serve,as
R12331 T15174 T15175 arg1Of repressor,or
R12332 T15175 T15172 arg2Of or,as
R12333 T15175 T15173 arg1Of or,a
R12334 T15175 T15177 arg1Of or,(
R12335 T15176 T15175 arg2Of activator,or
R12336 T15178 T15177 arg2Of 57,(
R12337 T15179 T15177 arg3Of ),(
R12338 T15184 T15182 arg2Of context,in
R12339 T15184 T15183 arg1Of context,the
R12340 T15184 T15185 arg1Of context,of
R12341 T15188 T15185 arg2Of promoter,of
R12342 T15188 T15186 arg1Of promoter,the
R12343 T15188 T15187 arg1Of promoter,A3G
R12344 T15192 T15190 arg1Of factors,both
R12345 T15192 T15191 arg1Of factors,transcription
R12346 T15192 T15193 arg1Of factors,serve
R12347 T15193 T15180 arg1Of serve,However
R12348 T15193 T15181 arg1Of serve,","
R12349 T15193 T15182 arg1Of serve,in
R12350 T15193 T15189 arg1Of serve,","
R12351 T15193 T15194 arg1Of serve,as
R12352 T15193 T15196 arg1Of serve,","
R12353 T15193 T15197 arg1Of serve,as
R12354 T15195 T15194 arg2Of activators,as
R12355 T15198 T15197 arg2Of shown,as
R12356 T15201 T15198 arg1Of silencing,shown
R12357 T15201 T15199 arg2Of silencing,by
R12358 T15201 T15200 arg1Of silencing,siRNA-mediated
R12359 T15201 T15202 arg1Of silencing,of
R12360 T15205 T15202 arg2Of factors,of
R12361 T15205 T15203 arg1Of factors,the
R12362 T15205 T15204 arg1Of factors,single
R12363 T15207 T15208 arg2Of siRNAs,directed
R12364 T15207 T15214 arg1Of siRNAs,reduced
R12365 T15208 T15209 arg1Of directed,against
R12366 T15210 T15211 arg1Of Sp1,or
R12367 T15211 T15209 arg2Of or,against
R12368 T15212 T15211 arg2Of Sp3,or
R12369 T15214 T15206 arg2Of reduced,Although
R12370 T15214 T15213 arg1Of reduced,significantly
R12371 T15215 T15214 arg2Of transcription,reduced
R12372 T15215 T15216 arg2Of transcription,controlled
R12373 T15220 T15216 arg1Of promoter,controlled
R12374 T15220 T15217 arg2Of promoter,by
R12375 T15220 T15218 arg1Of promoter,the
R12376 T15220 T15219 arg1Of promoter,180 bp
R12377 T15223 T15222 arg1Of activity,transcriptional
R12378 T15223 T15224 arg1Of activity,was
R12379 T15223 T15226 arg2Of activity,reduced
R12380 T15226 T15206 arg1Of reduced,Although
R12381 T15226 T15221 arg1Of reduced,","
R12382 T15226 T15224 arg2Of reduced,was
R12383 T15226 T15225 arg1Of reduced,not
R12384 T15226 T15227 arg1Of reduced,to
R12385 T15229 T15227 arg2Of level,to
R12386 T15229 T15228 arg1Of level,the
R12387 T15229 T15230 arg1Of level,of
R12388 T15233 T15230 arg2Of fragment,of
R12389 T15233 T15231 arg1Of fragment,the
R12390 T15233 T15232 arg1Of fragment,150 bp
R12391 T15234 T15235 arg1Of This,can
R12392 T15234 T15236 arg1Of This,be
R12393 T15234 T15237 arg2Of This,explained
R12394 T15237 T15235 arg2Of explained,can
R12395 T15237 T15236 arg2Of explained,be
R12396 T15242 T15237 arg1Of amounts,explained
R12397 T15242 T15238 arg2Of amounts,by
R12398 T15242 T15239 arg1Of amounts,the
R12399 T15242 T15240 arg1Of amounts,remaining
R124 T153 T152 arg1Of cDNA,of
R12400 T15242 T15241 arg1Of amounts,low
R12401 T15242 T15243 arg1Of amounts,of
R12402 T15242 T15246 arg1Of amounts,which
R12403 T15242 T15247 arg1Of amounts,can
R12404 T15242 T15248 arg1Of amounts,be
R12405 T15242 T15249 arg2Of amounts,seen
R12406 T15245 T15243 arg2Of proteins,of
R12407 T15245 T15244 arg1Of proteins,Sp1/Sp3
R12408 T15249 T15247 arg2Of seen,can
R12409 T15249 T15248 arg2Of seen,be
R12410 T15249 T15250 arg1Of seen,in
R12411 T15254 T15250 arg2Of analysis,in
R12412 T15254 T15251 arg1Of analysis,the
R12413 T15254 T15252 arg1Of analysis,western
R12414 T15254 T15253 arg1Of analysis,blot
R12415 T15259 T15257 arg1Of factors,other
R12416 T15259 T15258 arg1Of factors,transcription
R12417 T15259 T15260 arg1Of factors,could
R12418 T15259 T15261 arg1Of factors,be
R12419 T15259 T15262 arg2Of factors,involved
R12420 T15262 T15255 arg1Of involved,Alternatively
R12421 T15262 T15256 arg1Of involved,","
R12422 T15262 T15260 arg2Of involved,could
R12423 T15262 T15261 arg2Of involved,be
R12424 T15262 T15263 arg1Of involved,in
R12425 T15265 T15263 arg2Of regulation,in
R12426 T15265 T15264 arg1Of regulation,A3G
R12427 T15267 T15266 arg1Of results,Our
R12428 T15267 T15269 arg1Of results,provide
R12429 T15269 T15268 arg1Of provide,also
R12430 T15270 T15269 arg2Of information,provide
R12431 T15270 T15271 arg1Of information,about
R12432 T15270 T15279 arg1Of information,","
R12433 T15273 T15271 arg2Of regulation,about
R12434 T15273 T15272 arg1Of regulation,the
R12435 T15273 T15274 arg1Of regulation,of
R12436 T15275 T15274 arg2Of APOBEC3F,of
R12437 T15275 T15276 arg1Of APOBEC3F,(
R12438 T15277 T15276 arg2Of A3F,(
R12439 T15278 T15276 arg3Of ),(
R12440 T15281 T15279 arg2Of member,","
R12441 T15281 T15280 arg1Of member,another
R12442 T15281 T15282 arg1Of member,of
R12443 T15286 T15282 arg2Of family,of
R12444 T15286 T15283 arg1Of family,the
R12445 T15286 T15284 arg1Of family,human
R12446 T15286 T15285 arg1Of family,APOBEC3
R12447 T15287 T15288 arg1Of A3F,is
R12448 T15287 T15289 arg2Of A3F,expressed
R12449 T15289 T15288 arg2Of expressed,is
R12450 T15289 T15290 arg1Of expressed,in
R12451 T15289 T15298 arg1Of expressed,and
R12452 T15293 T15290 arg2Of tissues,in
R12453 T15293 T15291 arg1Of tissues,many
R12454 T15293 T15292 arg1Of tissues,human
R12455 T15293 T15294 arg1Of tissues,that
R12456 T15293 T15296 arg1Of tissues,express
R12457 T15296 T15295 arg1Of express,also
R12458 T15297 T15296 arg2Of A3G,express
R12459 T15300 T15299 arg1Of proteins,both
R12460 T15300 T15301 arg1Of proteins,have
R12461 T15300 T15302 arg1Of proteins,been
R12462 T15300 T15303 arg2Of proteins,shown
R12463 T15300 T15305 arg1Of proteins,form
R12464 T15303 T15298 arg2Of shown,and
R12465 T15303 T15301 arg2Of shown,have
R12466 T15303 T15302 arg2Of shown,been
R12467 T15305 T15303 arg3Of form,shown
R12468 T15305 T15304 arg1Of form,to
R12469 T15306 T15305 arg2Of heteromultimers,form
R12470 T15306 T15307 arg1Of heteromultimers,","
R12471 T15306 T15308 arg1Of heteromultimers,which
R12472 T15306 T15309 arg1Of heteromultimers,are
R12473 T15306 T15312 arg2Of heteromultimers,generated
R12474 T15311 T15310 arg1Of likely,most
R12475 T15312 T15309 arg2Of generated,are
R12476 T15312 T15311 arg1Of generated,likely
R12477 T15312 T15313 arg1Of generated,through
R12478 T15314 T15313 arg2Of binding,through
R12479 T15314 T15315 arg1Of binding,to
R12480 T15318 T15315 arg2Of intermediate,to
R12481 T15318 T15316 arg1Of intermediate,an
R12482 T15318 T15317 arg1Of intermediate,RNA
R12483 T15318 T15319 arg1Of intermediate,(
R12484 T15320 T15319 arg2Of "26,29,30",(
R12485 T15321 T15319 arg3Of ),(
R12486 T15322 T15324 arg1Of A3F,differs
R12487 T15324 T15323 arg1Of differs,only
R12488 T15324 T15325 arg1Of differs,in
R12489 T15324 T15330 arg1Of differs,upstream
R12490 T15326 T15325 arg2Of 16 nt,in
R12491 T15326 T15327 arg1Of 16 nt,from
R12492 T15329 T15327 arg2Of 560 nt,from
R12493 T15329 T15328 arg1Of 560 nt,the
R12494 T15330 T15331 arg1Of upstream,of
R12495 T15333 T15331 arg2Of TSS,of
R12496 T15333 T15332 arg1Of TSS,the
R12497 T15333 T15334 arg1Of TSS,of
R12498 T15335 T15334 arg2Of A3G,of
R12499 T15335 T15336 arg1Of A3G,(
R125 T153 T154 arg1Of cDNA,ends
R12500 T15338 T15337 arg1Of DQ146365,GenBank™
R12501 T15338 T15339 arg1Of DQ146365,and
R12502 T15339 T15336 arg2Of and,(
R12503 T15340 T15339 arg2Of DQ147772,and
R12504 T15341 T15336 arg3Of ),(
R12505 T15346 T15342 arg1Of region,The
R12506 T15346 T15343 arg1Of region,180-bp
R12507 T15346 T15344 arg1Of region,core
R12508 T15346 T15345 arg1Of region,promoter
R12509 T15346 T15347 arg1Of region,","
R12510 T15346 T15348 arg1Of region,which
R12511 T15346 T15350 arg2Of region,identified
R12512 T15346 T15353 arg1Of region,has
R12513 T15349 T15350 arg1Of we,identified
R12514 T15350 T15351 arg1Of identified,for
R12515 T15352 T15351 arg2Of A3G,for
R12516 T15354 T15355 arg1Of 100,%
R12517 T15356 T15353 arg2Of identity,has
R12518 T15356 T15354 arg1Of identity,100
R12519 T15356 T15357 arg1Of identity,with
R12520 T15360 T15357 arg2Of sequence,with
R12521 T15360 T15358 arg1Of sequence,the
R12522 T15360 T15359 arg1Of sequence,A3F
R12523 T15365 T15363 arg1Of factors,Sp1/Sp3
R12524 T15365 T15364 arg1Of factors,transcription
R12525 T15365 T15366 arg1Of factors,are
R12526 T15365 T15370 arg1Of factors,mediating
R12527 T15368 T15367 arg1Of likely,most
R12528 T15370 T15361 arg1Of mediating,Therefore
R12529 T15370 T15362 arg1Of mediating,","
R12530 T15370 T15366 arg2Of mediating,are
R12531 T15370 T15368 arg1Of mediating,likely
R12532 T15370 T15369 arg1Of mediating,also
R12533 T15372 T15370 arg2Of transcription,mediating
R12534 T15372 T15371 arg1Of transcription,basal
R12535 T15372 T15373 arg1Of transcription,of
R12536 T15376 T15373 arg2Of gene,of
R12537 T15376 T15374 arg1Of gene,the
R12538 T15376 T15375 arg1Of gene,A3F
R12539 T15378 T15377 arg1Of study,Our
R12540 T15378 T15379 arg1Of study,revealed
R12541 T15384 T15381 arg1Of gene,the
R12542 T15384 T15382 arg1Of gene,human
R12543 T15384 T15383 arg1Of gene,A3G
R12544 T15384 T15385 arg1Of gene,is
R12545 T15384 T15386 arg2Of gene,controlled
R12546 T15386 T15379 arg2Of controlled,revealed
R12547 T15386 T15380 arg1Of controlled,that
R12548 T15386 T15385 arg2Of controlled,is
R12549 T15389 T15386 arg1Of promoter,controlled
R12550 T15389 T15387 arg2Of promoter,by
R12551 T15389 T15388 arg1Of promoter,a
R12552 T15389 T15390 arg1Of promoter,with
R12553 T15394 T15390 arg2Of sites,with
R12554 T15394 T15391 arg1Of sites,multiple
R12555 T15394 T15392 arg1Of sites,transcriptional
R12556 T15394 T15393 arg1Of sites,start
R12557 T15397 T15395 arg2Of cells,In
R12558 T15397 T15396 arg1Of cells,A3.01 T
R12559 T15401 T15399 arg1Of promoter,the
R12560 T15401 T15400 arg1Of promoter,A3G
R12561 T15401 T15402 arg1Of promoter,appears
R12562 T15401 T15404 arg1Of promoter,active
R12563 T15401 T15406 arg1Of promoter,is
R12564 T15401 T15408 arg1Of promoter,inducible
R12565 T15402 T15405 arg1Of appears,and
R12566 T15404 T15402 arg2Of active,appears
R12567 T15404 T15403 arg1Of active,constitutively
R12568 T15405 T15395 arg1Of and,In
R12569 T15405 T15398 arg1Of and,","
R12570 T15405 T15409 arg1Of and,by
R12571 T15405 T15418 arg1Of and,by
R12572 T15406 T15405 arg2Of is,and
R12573 T15406 T15407 arg1Of is,not
R12574 T15408 T15406 arg2Of inducible,is
R12575 T15409 T15417 arg1Of by,or
R12576 T15410 T15409 arg2Of TPA,by
R12577 T15410 T15411 arg1Of TPA,","
R12578 T15413 T15414 arg1Of I,or
R12579 T15415 T15414 arg2Of II,or
R12580 T15416 T15411 arg2Of interferons,","
R12581 T15416 T15412 arg1Of interferons,type
R12582 T15416 T15413 arg1Of interferons,I
R12583 T15416 T15415 arg1Of interferons,II
R12584 T15418 T15417 arg2Of by,or
R12585 T15420 T15418 arg2Of proteins,by
R12586 T15420 T15419 arg1Of proteins,HIV-1
R12587 T15423 T15421 arg1Of promoter,The
R12588 T15423 T15422 arg1Of promoter,core
R12589 T15423 T15424 arg1Of promoter,is
R12590 T15423 T15425 arg1Of promoter,located
R12591 T15425 T15424 arg2Of located,is
R12592 T15425 T15426 arg1Of located,within
R12593 T15428 T15426 arg2Of region,within
R12594 T15428 T15427 arg1Of region,a
R12595 T15428 T15429 arg1Of region,of
R12596 T15428 T15431 arg1Of region,at
R12597 T15430 T15429 arg2Of 180 bp,of
R12598 T15432 T15431 arg2Of position,at
R12599 T15432 T15433 arg1Of position,−114/+66
R126 T154 T147 modOf ends,were
R12600 T15432 T15435 arg1Of position,to
R12601 T15435 T15434 arg1Of to,relative
R12602 T15437 T15435 arg2Of TSS,to
R12603 T15437 T15436 arg1Of TSS,the
R12604 T15439 T15438 arg1Of GC-box,A
R12605 T15439 T15440 arg1Of GC-box,is
R12606 T15439 T15441 arg1Of GC-box,crucial
R12607 T15439 T15450 arg1Of GC-box,represents
R12608 T15440 T15449 arg1Of is,and
R12609 T15441 T15440 arg2Of crucial,is
R12610 T15441 T15442 arg1Of crucial,to
R12611 T15444 T15442 arg2Of function,to
R12612 T15444 T15443 arg1Of function,the
R12613 T15444 T15445 arg1Of function,of
R12614 T15448 T15445 arg2Of promoter,of
R12615 T15448 T15446 arg1Of promoter,the
R12616 T15448 T15447 arg1Of promoter,core
R12617 T15450 T15449 arg2Of represents,and
R12618 T15453 T15450 arg2Of site,represents
R12619 T15453 T15451 arg1Of site,a
R12620 T15453 T15452 arg1Of site,binding
R12621 T15453 T15454 arg1Of site,for
R12622 T15455 T15456 arg1Of Sp1,and
R12623 T15457 T15456 arg2Of Sp3,and
R12624 T15459 T15454 arg2Of factors,for
R12625 T15459 T15455 arg1Of factors,Sp1
R12626 T15459 T15457 arg1Of factors,Sp3
R12627 T15459 T15458 arg1Of factors,transcription
R12628 T15461 T15460 arg1Of results,Our
R12629 T15461 T15462 arg1Of results,can
R12630 T15461 T15463 arg1Of results,serve
R12631 T15463 T15462 arg2Of serve,can
R12632 T15463 T15464 arg1Of serve,as
R12633 T15466 T15464 arg2Of basis,as
R12634 T15466 T15465 arg1Of basis,a
R12635 T15466 T15467 arg1Of basis,for
R12636 T15469 T15467 arg2Of studies,for
R12637 T15469 T15468 arg1Of studies,future
R12638 T15469 T15470 arg2Of studies,aimed
R12639 T15470 T15471 arg1Of aimed,at
R12640 T15472 T15471 arg2Of understanding,at
R12641 T15473 T15483 arg1Of how,and
R12642 T15474 T15475 arg1Of A3G,and
R12643 T15476 T15475 arg2Of A3F,and
R12644 T15477 T15474 arg1Of expression,A3G
R12645 T15477 T15476 arg1Of expression,A3F
R12646 T15477 T15478 arg1Of expression,is
R12647 T15477 T15479 arg2Of expression,controlled
R12648 T15479 T15473 arg1Of controlled,how
R12649 T15479 T15478 arg2Of controlled,is
R12650 T15479 T15480 arg1Of controlled,in
R12651 T15482 T15480 arg2Of tissues,in
R12652 T15482 T15481 arg1Of tissues,different
R12653 T15483 T15472 arg2Of and,understanding
R12654 T15484 T15483 arg2Of how,and
R12655 T15487 T15485 arg1Of factors,these
R12656 T15487 T15486 arg1Of factors,restriction
R12657 T15487 T15488 arg1Of factors,can
R12658 T15487 T15489 arg1Of factors,be
R12659 T15487 T15490 arg2Of factors,used
R12660 T15487 T15492 arg1Of factors,develop
R12661 T15490 T15484 arg1Of used,how
R12662 T15490 T15488 arg2Of used,can
R12663 T15490 T15489 arg2Of used,be
R12664 T15492 T15490 arg3Of develop,used
R12665 T15492 T15491 arg1Of develop,to
R12666 T15492 T15496 arg1Of develop,against
R12667 T15495 T15492 arg2Of strategies,develop
R12668 T15495 T15493 arg1Of strategies,novel
R12669 T15495 T15494 arg1Of strategies,therapeutic
R12670 T15498 T15496 arg2Of infection,against
R12671 T15498 T15497 arg1Of infection,HIV-1
R127 T155 T154 arg2Of analysis,ends
R128 T158 T156 arg1Of assays,Luciferase
R129 T158 T157 arg1Of assays,reporter
R130 T158 T159 arg1Of assays,demonstrated
R131 T165 T161 arg1Of sequence,a
R132 T165 T162 arg1Of sequence,1025 bp
R133 T165 T163 arg1Of sequence,A3G
R134 T165 T164 arg1Of sequence,promoter
R135 T165 T166 arg1Of sequence,(
R136 T165 T179 arg1Of sequence,displayed
R137 T167 T166 arg2Of from,(
R138 T170 T167 arg2Of +66,from
R139 T170 T168 arg1Of +66,−959
R140 T170 T169 arg1Of +66,to
R141 T170 T172 arg1Of +66,to
R142 T172 T171 arg1Of to,relative
R143 T177 T172 arg2Of site,to
R144 T177 T173 arg1Of site,the
R145 T177 T174 arg1Of site,major
R146 T177 T175 arg1Of site,transcriptional
R147 T177 T176 arg1Of site,start
R148 T178 T166 arg3Of ),(
R149 T179 T159 arg2Of displayed,demonstrated
R14936 T18365 T18366 arg1Of Sequence,of
R14937 T18365 T18370 arg1Of Sequence,and
R14938 T18369 T18366 arg2Of promoter,of
R14939 T18369 T18367 arg1Of promoter,the
R14940 T18369 T18368 arg1Of promoter,A3G
R14941 T18373 T18370 arg2Of region,and
R14942 T18373 T18371 arg1Of region,the
R14943 T18373 T18372 arg1Of region,downstream
R14944 T18376 T18374 arg1Of 1000 bp,The
R14945 T18376 T18375 arg1Of 1000 bp,first
R14946 T18376 T18377 arg1Of 1000 bp,upstream
R14947 T18376 T18382 arg1Of 1000 bp,are
R14948 T18376 T18383 arg2Of 1000 bp,shown
R14949 T18377 T18378 arg1Of upstream,of
R14950 T18381 T18378 arg2Of TSS,of
R14951 T18381 T18379 arg1Of TSS,the
R14952 T18381 T18380 arg1Of TSS,major
R14953 T18383 T18382 arg2Of shown,are
R14954 T18383 T18384 arg1Of shown,in
R14955 T18386 T18384 arg2Of case,in
R14956 T18386 T18385 arg1Of case,lower
R14957 T18390 T18388 arg1Of 800 bp,the
R14958 T18390 T18389 arg1Of 800 bp,first
R14959 T18390 T18391 arg1Of 800 bp,of
R14960 T18390 T18395 arg1Of 800 bp,are
R14961 T18390 T18396 arg2Of 800 bp,shown
R14962 T18394 T18391 arg2Of sequence,of
R14963 T18394 T18392 arg1Of sequence,the
R14964 T18394 T18393 arg2Of sequence,transcribed
R14965 T18396 T18382 modOf shown,are
R14966 T18396 T18387 arg1Of shown,","
R14967 T18396 T18395 arg2Of shown,are
R14968 T18396 T18397 arg1Of shown,in
R14969 T18399 T18397 arg2Of case,in
R14970 T18399 T18398 arg1Of case,upper
R14971 T18400 T18401 arg1Of Introns,are
R14972 T18400 T18402 arg2Of Introns,removed
R14973 T18402 T18401 arg2Of removed,are
R14974 T18402 T18404 arg1Of removed,but
R14975 T18404 T18403 arg1Of but,","
R14976 T18406 T18405 arg1Of positions,their
R14977 T18406 T18407 arg1Of positions,are
R14978 T18406 T18408 arg2Of positions,indicated
R14979 T18408 T18404 arg2Of indicated,but
R14980 T18408 T18407 arg2Of indicated,are
R14981 T18409 T18410 arg1Of Arrows,refer
R14982 T18410 T18411 arg1Of refer,to
R14983 T18410 T18415 arg1Of refer,and
R14984 T18414 T18411 arg2Of sites,to
R14985 T18414 T18412 arg1Of sites,transcriptional
R14986 T18414 T18413 arg1Of sites,start
R14987 T18418 T18416 arg1Of frequency,their
R14988 T18418 T18417 arg2Of frequency,observed
R14989 T18418 T18419 arg1Of frequency,is
R14990 T18418 T18420 arg2Of frequency,given
R14991 T18420 T18415 arg2Of given,and
R14992 T18420 T18419 arg2Of given,is
R14993 T18420 T18424 arg1Of given,above
R14994 T18423 T18420 arg1Of numbers,given
R14995 T18423 T18421 arg2Of numbers,by
R14996 T18423 T18422 arg1Of numbers,the
R14997 T18428 T18425 arg1Of sites,The
R14998 T18428 T18426 arg1Of sites,primer
R14999 T18428 T18427 arg1Of sites,binding
R150 T179 T160 arg1Of displayed,that
R15000 T18428 T18429 arg1Of sites,for
R15001 T18428 T18439 arg1Of sites,are
R15002 T18428 T18440 arg2Of sites,underlined
R15003 T18431 T18430 arg1Of analysis,5′-RACE
R15004 T18431 T18432 arg1Of analysis,and
R15005 T18432 T18429 arg2Of and,for
R15006 T18432 T18434 arg1Of and,of
R15007 T18433 T18432 arg2Of cloning,and
R15008 T18438 T18434 arg2Of constructs,of
R15009 T18438 T18435 arg1Of constructs,the
R15010 T18438 T18436 arg1Of constructs,luciferase
R15011 T18438 T18437 arg1Of constructs,reporter
R15012 T18440 T18439 arg2Of underlined,are
R15013 T18440 T18441 arg1Of underlined,and
R15014 T18443 T18442 arg1Of names,the
R15015 T18443 T18444 arg1Of names,of
R15016 T18443 T18447 arg1Of names,are
R15017 T18443 T18448 arg2Of names,annotated
R15018 T18446 T18444 arg2Of primers,of
R15019 T18446 T18445 arg1Of primers,the
R15020 T18448 T18441 arg2Of annotated,and
R15021 T18448 T18447 arg2Of annotated,are
R15022 T18449 T18450 arg1Of Gray,and
R15023 T18450 T18453 arg1Of and,define
R15024 T18452 T18450 arg2Of arrowheads,and
R15025 T18452 T18451 arg1Of arrowheads,black
R15026 T18455 T18453 arg2Of regions,define
R15027 T18455 T18454 arg1Of regions,the
R15028 T18455 T18456 arg2Of regions,designated
R15029 T18455 T18460 arg1Of regions,which
R15030 T18455 T18461 arg1Of regions,were
R15031 T18455 T18462 arg2Of regions,cloned
R15032 T18455 T18467 arg2Of regions,used
R15033 T18457 T18458 arg1Of E1,and
R15034 T18458 T18456 arg3Of and,designated
R15035 T18459 T18458 arg2Of E2,and
R15036 T18462 T18463 arg1Of cloned,into
R15037 T18462 T18466 arg1Of cloned,and
R15038 T18465 T18463 arg2Of pGL3-Promoter,into
R15039 T18465 T18464 arg1Of pGL3-Promoter,vector
R15040 T18466 T18461 arg2Of and,were
R15041 T18467 T18466 arg2Of used,and
R15042 T18467 T18468 arg1Of used,as
R15043 T18470 T18468 arg2Of probes,as
R15044 T18470 T18469 arg1Of probes,EMSA
R15045 T18474 T18471 arg1Of codon,The
R15046 T18474 T18472 arg1Of codon,ATG
R15047 T18474 T18473 arg1Of codon,start
R15048 T18474 T18475 arg1Of codon,and
R15049 T18475 T18483 arg1Of and,are
R15050 T18475 T18484 arg2Of and,shown
R15051 T18482 T18475 arg2Of site,and
R15052 T18482 T18476 arg1Of site,the
R15053 T18482 T18477 arg2Of site,identified
R15054 T18482 T18478 arg1Of site,Sp1/Sp3
R15055 T18482 T18479 arg1Of site,transcription
R15056 T18482 T18480 arg1Of site,factor
R15057 T18482 T18481 arg1Of site,binding
R15058 T18484 T18483 arg2Of shown,are
R15059 T18484 T18485 arg1Of shown,in
R15060 T18486 T18485 arg2Of bold,in
R151 T182 T179 arg2Of activity,displayed
R15195 T18679 T18678 arg1Of analysis,5′-RACE
R15196 T18679 T18680 arg1Of analysis,of
R15197 T18683 T18680 arg2Of cDNA,of
R15198 T18683 T18681 arg1Of cDNA,the
R15199 T18683 T18682 arg1Of cDNA,A3G
R152 T182 T180 arg1Of activity,constitutive
R15200 T18686 T18684 arg1Of electrophoresis,Agarose
R15201 T18686 T18685 arg1Of electrophoresis,gel
R15202 T18686 T18687 arg1Of electrophoresis,of
R15203 T18686 T18694 arg1Of electrophoresis,after
R15204 T18686 T18701 modOf electrophoresis,see
R15205 T18686 T18704 arg1Of electrophoresis,for
R15206 T18686 T18707 arg1Of electrophoresis,)
R15207 T18689 T18688 arg1Of marker,size
R15208 T18689 T18690 arg1Of marker,and
R15209 T18690 T18687 arg2Of and,of
R15210 T18693 T18690 arg2Of products,and
R15211 T18693 T18691 arg1Of products,A3G
R15212 T18693 T18692 arg1Of products,5′-RACE
R15213 T18696 T18694 arg2Of PCR,after
R15214 T18696 T18695 arg1Of PCR,nested
R15215 T18696 T18697 arg1Of PCR,with
R15216 T18699 T18697 arg2Of RACE-APO3Gnest,with
R15217 T18699 T18698 arg1Of RACE-APO3Gnest,primer
R15218 T18701 T18700 arg1Of see,(
R15219 T18702 T18701 arg2Of Figure,see
R15220 T18702 T18703 arg1Of Figure,1
R15221 T18706 T18704 arg2Of details,for
R15222 T18706 T18705 arg1Of details,primer
R15223 T18708 T18709 arg1Of Arrowheads,indicate
R15224 T18714 T18709 arg2Of bands,indicate
R15225 T18714 T18710 arg1Of bands,the
R15226 T18714 T18711 arg1Of bands,three
R15227 T18714 T18712 arg1Of bands,resulting
R15228 T18714 T18713 arg1Of bands,DNA
R15229 T18714 T18715 arg1Of bands,which
R15230 T18714 T18716 arg1Of bands,were
R15231 T18714 T18717 arg2Of bands,cloned
R15232 T18714 T18719 arg2Of bands,sequenced
R15233 T18717 T18718 arg1Of cloned,and
R15234 T18718 T18716 arg2Of and,were
R15235 T18719 T18718 arg2Of sequenced,and
R15299 T18854 T18853 arg1Of activities,Luciferase
R153 T182 T181 arg1Of activity,promoter
R15300 T18854 T18855 arg1Of activities,of
R15301 T18854 T18874 arg1Of activities,were
R15302 T18854 T18875 arg2Of activities,cloned
R15303 T18858 T18855 arg2Of constructs,of
R15304 T18858 T18856 arg1Of constructs,A3G
R15305 T18858 T18857 arg1Of constructs,promoter
R15306 T18858 T18859 arg1Of constructs,in
R15307 T18862 T18860 arg1Of lines.,different
R15308 T18862 T18861 arg1Of lines.,cell
R15309 T18862 T18863 arg1Of lines.,(
R15310 T18864 T18863 arg2Of A,(
R15311 T18865 T18863 arg3Of ),(
R15312 T18870 T18859 arg2Of constructs,in
R15313 T18870 T18862 arg1Of constructs,lines.
R15314 T18870 T18866 arg1Of constructs,A3G
R15315 T18870 T18867 arg1Of constructs,promoter
R15316 T18870 T18868 arg1Of constructs,5′
R15317 T18870 T18869 arg1Of constructs,deletion
R15318 T18870 T18871 arg1Of constructs,of
R15319 T18873 T18871 arg2Of sizes,of
R15320 T18873 T18872 arg1Of sizes,different
R15321 T18875 T18874 arg2Of cloned,were
R15322 T18875 T18876 arg1Of cloned,into
R15323 T18880 T18876 arg2Of plasmids,into
R15324 T18880 T18877 arg1Of plasmids,pGL3-Basic
R15325 T18880 T18878 arg1Of plasmids,luciferase
R15326 T18880 T18879 arg1Of plasmids,reporter
R15327 T18881 T18882 arg1Of Numbering,is
R15328 T18881 T18883 arg1Of Numbering,relative
R15329 T18883 T18882 arg2Of relative,is
R15330 T18883 T18884 arg1Of relative,to
R15331 T18887 T18884 arg2Of TSS,to
R15332 T18887 T18885 arg1Of TSS,the
R15333 T18887 T18886 arg1Of TSS,major
R15334 T18892 T18888 arg1Of site,A
R15335 T18892 T18889 arg1Of site,putative
R15336 T18892 T18890 arg1Of site,Sp1/Sp3
R15337 T18892 T18891 arg1Of site,consensus
R15338 T18892 T18893 arg1Of site,(
R15339 T18892 T18897 arg1Of site,is
R15340 T18892 T18898 arg2Of site,depicted.
R15341 T18895 T18893 arg2Of square,(
R15342 T18895 T18894 arg1Of square,gray
R15343 T18896 T18893 arg3Of ),(
R15344 T18898 T18897 arg2Of depicted.,is
R15345 T18900 T18899 arg2Of B,(
R15346 T18901 T18899 arg3Of ),(
R15347 T18903 T18899 arg1Of cells,(
R15348 T18903 T18902 arg1Of cells,A3.01 T
R15349 T18903 T18904 arg1Of cells,were
R15350 T18903 T18906 arg2Of cells,transfected
R15351 T18906 T18897 modOf transfected,is
R15352 T18906 T18904 arg2Of transfected,were
R15353 T18906 T18905 arg1Of transfected,transiently
R15354 T18906 T18907 arg1Of transfected,with
R15355 T18912 T18907 arg2Of constructs,with
R15356 T18912 T18908 arg1Of constructs,the
R15357 T18912 T18909 arg1Of constructs,A3G
R15358 T18912 T18910 arg1Of constructs,promoter
R15359 T18912 T18911 arg1Of constructs,deletion
R15360 T18913 T18914 arg1Of Numbers,on
R15361 T18913 T18917 arg1Of Numbers,refer
R15362 T18916 T18914 arg2Of x-axis,on
R15363 T18916 T18915 arg1Of x-axis,the
R15364 T18917 T18918 arg1Of refer,to
R15365 T18920 T18918 arg2Of length,to
R15366 T18920 T18919 arg1Of length,the
R15367 T18920 T18921 arg1Of length,of
R15368 T18920 T18926 arg1Of length,in
R15369 T18925 T18921 arg2Of fragments,of
R15370 T18925 T18922 arg1Of fragments,the
R15371 T18925 T18923 arg1Of fragments,A3G
R15372 T18925 T18924 arg1Of fragments,promoter
R15373 T18927 T18926 arg2Of bp.,in
R15374 T18927 T18934 modOf bp.,were
R15375 T18929 T18928 arg2Of C,(
R15376 T18930 T18928 arg3Of ),(
R15377 T18933 T18928 arg1Of plasmids,(
R15378 T18933 T18931 arg1Of plasmids,A3G
R15379 T18933 T18932 arg1Of plasmids,promoter
R15380 T18933 T18934 arg1Of plasmids,were
R15381 T18933 T18935 arg2Of plasmids,transfected
R15382 T18935 T18934 arg2Of transfected,were
R15383 T18935 T18936 arg1Of transfected,into
R15384 T18937 T18938 arg1Of U937,","
R15385 T18938 T18940 arg1Of ",",and
R15386 T18939 T18938 arg2Of HepG2,","
R15387 T18940 T18936 arg2Of and,into
R15388 T18943 T18940 arg2Of lines,and
R15389 T18943 T18941 arg1Of lines,Huh7
R15390 T18943 T18942 arg1Of lines,cell
R15391 T18944 T18945 arg1Of Numbers,in
R15392 T18944 T18948 arg1Of Numbers,refer
R15393 T18947 T18945 arg2Of legends,in
R15394 T18947 T18946 arg1Of legends,the
R15395 T18948 T18949 arg1Of refer,to
R15396 T18948 T18960 arg1Of refer,","
R15397 T18951 T18949 arg2Of length,to
R15398 T18951 T18950 arg1Of length,the
R15399 T18951 T18952 arg1Of length,of
R154 T185 T183 arg2Of cells,In
R15400 T18956 T18952 arg2Of fragments,of
R15401 T18956 T18953 arg1Of fragments,the
R15402 T18956 T18954 arg1Of fragments,A3G
R15403 T18956 T18955 arg1Of fragments,promoter
R15404 T18956 T18957 arg1Of fragments,in
R15405 T18959 T18957 arg2Of 48 h,in
R15406 T18959 T18958 arg1Of 48 h,bp. After
R15407 T18961 T18962 arg1Of cells,were
R15408 T18961 T18963 arg2Of cells,harvested
R15409 T18963 T18960 arg2Of harvested,","
R15410 T18963 T18962 arg2Of harvested,were
R15411 T18963 T18964 arg1Of harvested,for
R15412 T18966 T18964 arg2Of assay,for
R15413 T18966 T18965 arg1Of assay,luciferase
R15414 T18969 T18967 arg1Of activities,Firefly
R15415 T18969 T18968 arg1Of activities,luciferase
R15416 T18969 T18970 arg1Of activities,were
R15417 T18969 T18971 arg2Of activities,normalized
R15418 T18971 T18970 arg2Of normalized,were
R15419 T18971 T18972 arg1Of normalized,to
R15420 T18976 T18972 arg2Of activities,to
R15421 T18976 T18973 arg2Of activities,coexpressed
R15422 T18976 T18974 arg1Of activities,renilla
R15423 T18976 T18975 arg1Of activities,luciferase
R15424 T18978 T18977 arg1Of values,Mean
R15425 T18978 T18979 arg1Of values,(
R15426 T18978 T18982 arg1Of values,of
R15427 T18978 T18989 arg1Of values,are
R15428 T18978 T18990 arg2Of values,shown
R15429 T18980 T18979 arg2Of ±SD,(
R15430 T18981 T18979 arg3Of ),(
R15431 T18985 T18982 arg2Of experiment,of
R15432 T18985 T18983 arg1Of experiment,a
R15433 T18985 T18984 arg1Of experiment,representative
R15434 T18985 T18986 arg2Of experiment,performed
R15435 T18986 T18987 arg1Of performed,in
R15436 T18988 T18987 arg2Of triplicate,in
R15437 T18990 T18989 arg2Of shown,are
R155 T185 T184 arg1Of cells,T
R156 T189 T187 arg1Of promoter,the
R15642 T19408 T19406 arg1Of activities,A3G
R15643 T19408 T19407 arg1Of activities,promoter
R15644 T19408 T19409 arg1Of activities,after
R15645 T19410 T19411 arg1Of coexpression,of
R15646 T19410 T19414 arg1Of coexpression,or
R15647 T19413 T19411 arg2Of proteins,of
R15648 T19413 T19412 arg1Of proteins,HIV-1
R15649 T19414 T19409 arg2Of or,after
R15650 T19415 T19414 arg2Of treatment,or
R15651 T19415 T19416 arg1Of treatment,with
R15652 T19415 T19425 modOf treatment,were
R15653 T19417 T19418 arg1Of TPA,or
R15654 T19418 T19416 arg2Of or,with
R15655 T19418 T19420 arg1Of or,(
R15656 T19419 T19418 arg2Of interferons.,or
R15657 T19421 T19420 arg2Of A,(
R15658 T19422 T19420 arg3Of ),(
R15659 T19424 T19423 arg1Of cells,A3.01 T
R15660 T19424 T19425 arg1Of cells,were
R15661 T19424 T19426 arg2Of cells,cotransfected
R15662 T19426 T19425 arg2Of cotransfected,were
R15663 T19426 T19427 arg1Of cotransfected,with
R15664 T19430 T19428 arg1Of plasmid,pGL3-Basic
R15665 T19430 T19429 arg1Of plasmid,reporter
R15666 T19430 T19431 arg1Of plasmid,containing
R15667 T19430 T19436 arg1Of plasmid,and
R15668 T19435 T19431 arg2Of promoter,containing
R15669 T19435 T19432 arg1Of promoter,the
R15670 T19435 T19433 arg1Of promoter,1025 bp
R15671 T19435 T19434 arg1Of promoter,A3G
R15672 T19436 T19427 arg2Of and,with
R15673 T19436 T19452 arg1Of and,(
R15674 T19437 T19436 arg2Of 1 µg,and
R15675 T19437 T19438 arg1Of 1 µg,of
R15676 T19441 T19439 arg1Of plasmid,Vif
R15677 T19441 T19440 arg1Of plasmid,expression
R15678 T19441 T19442 arg1Of plasmid,","
R15679 T19442 T19447 arg1Of ",",or
R15680 T19446 T19442 arg2Of plasmid,","
R15681 T19446 T19443 arg1Of plasmid,1 µg
R15682 T19446 T19444 arg1Of plasmid,Tat
R15683 T19446 T19445 arg1Of plasmid,expression
R15684 T19447 T19438 arg2Of or,of
R15685 T19449 T19447 arg2Of amounts,or
R15686 T19449 T19448 arg1Of amounts,increasing
R15687 T19449 T19450 arg1Of amounts,of
R15688 T19451 T19450 arg2Of HIV-1NL4-3,of
R15689 T19453 T19454 arg1Of 0.1,","
R15690 T19454 T19456 arg1Of ",",and
R15691 T19455 T19454 arg2Of 0.5,","
R15692 T19456 T19452 arg2Of and,(
R15693 T19457 T19456 arg2Of 1 µg,and
R15694 T19458 T19452 arg3Of ),(
R15695 T19460 T19459 arg2Of 48 h,After
R15696 T19462 T19463 arg1Of cells,were
R15697 T19462 T19464 arg2Of cells,harvested
R15698 T19464 T19459 arg1Of harvested,After
R15699 T19464 T19461 arg1Of harvested,","
R157 T189 T188 arg1Of promoter,A3G
R15700 T19464 T19463 arg2Of harvested,were
R15701 T19464 T19465 arg1Of harvested,for
R15702 T19467 T19465 arg2Of assay,for
R15703 T19467 T19466 arg1Of assay,luciferase
R15704 T19470 T19468 arg1Of activities,Firefly
R15705 T19470 T19469 arg1Of activities,luciferase
R15706 T19470 T19471 arg1Of activities,were
R15707 T19470 T19472 arg2Of activities,normalized
R15708 T19472 T19471 arg2Of normalized,were
R15709 T19472 T19473 arg1Of normalized,to
R15710 T19477 T19473 arg2Of activities.,to
R15711 T19477 T19474 arg2Of activities.,coexpressed
R15712 T19477 T19475 arg1Of activities.,renilla
R15713 T19477 T19476 arg1Of activities.,luciferase
R15714 T19477 T19483 modOf activities.,were
R15715 T19479 T19478 arg2Of B,(
R15716 T19480 T19478 arg3Of ),(
R15717 T19482 T19478 arg1Of cells,(
R15718 T19482 T19481 arg1Of cells,A3.01 T
R15719 T19482 T19483 arg1Of cells,were
R15720 T19482 T19485 arg2Of cells,transfected
R15721 T19485 T19483 arg2Of transfected,were
R15722 T19485 T19484 arg1Of transfected,transiently
R15723 T19485 T19486 arg1Of transfected,with
R15724 T19485 T19496 arg1Of transfected,with
R15725 T19486 T19495 arg1Of with,or
R15726 T19489 T19486 arg2Of plasmid,with
R15727 T19489 T19487 arg1Of plasmid,pGL3-Basic
R15728 T19489 T19488 arg1Of plasmid,reporter
R15729 T19489 T19490 arg1Of plasmid,containing
R15730 T19494 T19490 arg2Of promoter,containing
R15731 T19494 T19491 arg1Of promoter,the
R15732 T19494 T19492 arg1Of promoter,1025 bp
R15733 T19494 T19493 arg1Of promoter,A3G
R15734 T19496 T19495 arg2Of with,or
R15735 T19498 T19496 arg2Of vector,with
R15736 T19498 T19497 arg1Of vector,empty
R15737 T19500 T19499 arg1Of hour,Fifteen
R15738 T19501 T19500 arg1Of before,hour
R15739 T19502 T19501 arg2Of harvesting,before
R15740 T19502 T19503 arg1Of harvesting,for
R15741 T19505 T19503 arg2Of assay,for
R15742 T19505 T19504 arg1Of assay,luciferase
R15743 T19508 T19507 arg1Of subset,a
R15744 T19508 T19509 arg1Of subset,of
R15745 T19508 T19513 arg1Of subset,was
R15746 T19508 T19514 arg2Of subset,stimulated
R15747 T19512 T19509 arg2Of culture,of
R15748 T19512 T19510 arg1Of culture,the
R15749 T19512 T19511 arg1Of culture,cell
R15750 T19514 T19501 arg1Of stimulated,before
R15751 T19514 T19506 arg1Of stimulated,","
R15752 T19514 T19513 arg2Of stimulated,was
R15753 T19514 T19515 arg1Of stimulated,with
R15754 T19517 T19515 arg2Of TPA,with
R15755 T19517 T19516 arg1Of TPA,20 ng/ml
R15756 T19519 T19518 arg1Of hour,Forty-eight
R15757 T19520 T19519 arg1Of after,hour
R15758 T19521 T19520 arg2Of transfection,after
R15759 T19524 T19523 arg1Of assay,luciferase
R15760 T19524 T19525 arg1Of assay,was
R15761 T19524 T19526 arg2Of assay,performed
R15762 T19526 T19520 arg1Of performed,after
R15763 T19526 T19522 arg1Of performed,","
R15764 T19526 T19525 arg2Of performed,was
R15765 T19529 T19527 arg1Of activities,Firefly
R15766 T19529 T19528 arg1Of activities,luciferase
R15767 T19529 T19530 arg1Of activities,were
R15768 T19529 T19531 arg2Of activities,normalized
R15769 T19529 T19558 arg1Of activities,were
R15770 T19529 T19560 arg2Of activities,transfected
R15771 T19531 T19530 arg2Of normalized,were
R15772 T19531 T19532 arg1Of normalized,to
R15773 T19531 T19537 arg1Of normalized,and
R15774 T19536 T19532 arg2Of activities,to
R15775 T19536 T19533 arg2Of activities,coexpressed
R15776 T19536 T19534 arg1Of activities,renilla
R15777 T19536 T19535 arg1Of activities,luciferase
R15778 T19539 T19538 arg1Of values,the
R15779 T19539 T19540 arg1Of values,for
R15780 T19539 T19549 arg1Of values,were
R15781 T19539 T19550 arg2Of values,set
R15782 T19543 T19540 arg2Of vectors,for
R15783 T19543 T19541 arg1Of vectors,the
R15784 T19543 T19542 arg1Of vectors,empty
R15785 T19543 T19544 arg1Of vectors,(
R15786 T19545 T19546 arg1Of untreated,and
R15787 T19547 T19544 arg2Of TPA-stimulated,(
R15788 T19547 T19545 arg1Of TPA-stimulated,untreated
R15789 T19548 T19544 arg3Of ),(
R15790 T19550 T19549 arg2Of set,were
R15791 T19550 T19551 arg1Of set,as
R15792 T19554 T19553 arg2Of C,(
R15793 T19555 T19553 arg3Of ),(
R15794 T19557 T19551 arg2Of cells,as
R15795 T19557 T19552 arg1Of cells,1.
R15796 T19557 T19553 arg1Of cells,(
R15797 T19557 T19556 arg1Of cells,A3.01 T
R15798 T19560 T19537 arg2Of transfected,and
R15799 T19560 T19549 modOf transfected,were
R158 T189 T190 arg1Of promoter,was
R15800 T19560 T19558 arg2Of transfected,were
R15801 T19560 T19559 arg1Of transfected,transiently
R15802 T19560 T19561 arg1Of transfected,with
R15803 T19560 T19567 arg1Of transfected,with
R15804 T19561 T19566 arg1Of with,or
R15805 T19565 T19561 arg2Of constructs,with
R15806 T19565 T19562 arg1Of constructs,the
R15807 T19565 T19563 arg1Of constructs,A3G
R15808 T19565 T19564 arg1Of constructs,promoter
R15809 T19567 T19566 arg2Of with,or
R15810 T19572 T19567 arg2Of pGL2-CVX,with
R15811 T19572 T19568 arg1Of pGL2-CVX,the
R15812 T19572 T19569 arg1Of pGL2-CVX,interferon-responsive
R15813 T19572 T19570 arg1Of pGL2-CVX,reporter
R15814 T19572 T19571 arg1Of pGL2-CVX,plasmid
R15815 T19572 T19573 arg1Of pGL2-CVX,(
R15816 T19574 T19573 arg2Of GAS,(
R15817 T19575 T19573 arg3Of ),(
R15818 T19577 T19576 arg1Of hour,Fifteen
R15819 T19578 T19577 arg1Of before,hour
R15820 T19579 T19578 arg2Of harvesting,before
R15821 T19579 T19580 arg1Of harvesting,for
R15822 T19582 T19580 arg2Of assay,for
R15823 T19582 T19581 arg1Of assay,luciferase
R15824 T19585 T19584 arg1Of subset,a
R15825 T19585 T19586 arg1Of subset,of
R15826 T19585 T19590 arg1Of subset,was
R15827 T19585 T19591 arg2Of subset,stimulated
R15828 T19589 T19586 arg2Of culture,of
R15829 T19589 T19587 arg1Of culture,the
R15830 T19589 T19588 arg1Of culture,cell
R15831 T19591 T19578 arg1Of stimulated,before
R15832 T19591 T19583 arg1Of stimulated,","
R15833 T19591 T19590 arg2Of stimulated,was
R15834 T19591 T19592 arg1Of stimulated,with
R15835 T19594 T19595 arg1Of IFN-α,or
R15836 T19595 T19592 arg2Of or,with
R15837 T19595 T19593 arg1Of or,30 ng/ml
R15838 T19596 T19595 arg2Of IFN-γ,or
R15839 T19598 T19597 arg1Of hour,Forty-eight
R15840 T19599 T19598 arg1Of after,hour
R15841 T19600 T19599 arg2Of transfection,after
R15842 T19603 T19602 arg1Of assay,luciferase
R15843 T19603 T19604 arg1Of assay,was
R15844 T19603 T19605 arg2Of assay,performed
R15845 T19605 T19599 arg1Of performed,after
R15846 T19605 T19601 arg1Of performed,","
R15847 T19605 T19604 arg2Of performed,was
R15848 T19608 T19606 arg1Of activities,Firefly
R15849 T19608 T19607 arg1Of activities,luciferase
R15850 T19608 T19609 arg1Of activities,were
R15851 T19608 T19610 arg2Of activities,normalized
R15852 T19610 T19609 arg2Of normalized,were
R15853 T19610 T19611 arg1Of normalized,to
R15854 T19610 T19623 arg1Of normalized,for
R15855 T19615 T19611 arg2Of activities.,to
R15856 T19615 T19612 arg2Of activities.,coexpressed
R15857 T19615 T19613 arg1Of activities.,renilla
R15858 T19615 T19614 arg1Of activities.,luciferase
R15859 T19615 T19616 arg1Of activities.,(
R15860 T19615 T19621 modOf activities.,were
R15861 T19617 T19616 arg2Of D,(
R15862 T19618 T19616 arg3Of ),(
R15863 T19620 T19619 arg1Of cells,HepG2
R15864 T19620 T19621 arg1Of cells,were
R15865 T19620 T19622 arg2Of cells,used
R15866 T19622 T19621 arg2Of used,were
R15867 T19624 T19623 arg2Of transfection,for
R15868 T19626 T19625 arg1Of experiment,The
R15869 T19626 T19627 arg1Of experiment,was
R15870 T19626 T19628 arg2Of experiment,performed
R15871 T19628 T19627 arg2Of performed,was
R15872 T19628 T19629 arg1Of performed,as
R15873 T19630 T19629 arg2Of described,as
R15874 T19630 T19631 arg1Of described,in
R15875 T19633 T19631 arg2Of C,in
R15876 T19633 T19632 arg2Of C,(
R15877 T19634 T19632 arg3Of ),(
R15878 T19636 T19635 arg1Of values,Mean
R15879 T19636 T19637 arg1Of values,(
R15880 T19636 T19640 arg1Of values,of
R15881 T19636 T19646 arg1Of values,are
R15882 T19636 T19647 arg2Of values,shown
R15883 T19638 T19637 arg2Of ±SD,(
R15884 T19639 T19637 arg3Of ),(
R15885 T19642 T19640 arg2Of experiments,of
R15886 T19642 T19641 arg1Of experiments,representative
R15887 T19642 T19643 arg2Of experiments,performed
R15888 T19643 T19644 arg1Of performed,in
R15889 T19645 T19644 arg2Of triplicate,in
R15890 T19647 T19646 arg2Of shown,are
R159 T189 T192 arg1Of promoter,inducible
R160 T190 T183 arg1Of was,In
R161 T190 T186 arg1Of was,","
R162 T190 T191 arg1Of was,not
R16213 T20232 T20231 arg1Of GC-box,A
R16214 T20232 T20233 arg1Of GC-box,mediates
R16215 T20235 T20233 arg2Of activity,mediates
R16216 T20235 T20234 arg1Of activity,transcriptional
R16217 T20235 T20236 arg1Of activity,of
R16218 T20240 T20236 arg2Of promoter.,of
R16219 T20240 T20237 arg1Of promoter.,the
R16220 T20240 T20238 arg1Of promoter.,180 bp
R16221 T20240 T20239 arg1Of promoter.,core
R16222 T20240 T20241 arg1Of promoter.,(
R16223 T20240 T20246 modOf promoter.,were
R16224 T20242 T20241 arg2Of A,(
R16225 T20243 T20241 arg3Of ),(
R16226 T20245 T20244 arg1Of cells,A3.01 T
R16227 T20245 T20246 arg1Of cells,were
R16228 T20245 T20247 arg2Of cells,transfected
R16229 T20247 T20246 arg2Of transfected,were
R16230 T20247 T20248 arg1Of transfected,with
R16231 T20250 T20248 arg2Of plasmid,with
R16232 T20250 T20249 arg1Of plasmid,reporter
R16233 T20250 T20251 arg1Of plasmid,pGL3-Basic
R16234 T20250 T20252 arg1Of plasmid,containing
R16235 T20253 T20254 arg1Of 180,","
R16236 T20254 T20256 arg1Of ",",or
R16237 T20255 T20254 arg2Of 150,","
R16238 T20256 T20252 arg2Of or,containing
R16239 T20257 T20256 arg2Of 120 bp,or
R16240 T20257 T20258 arg1Of 120 bp,of
R16241 T20261 T20258 arg2Of promoter,of
R16242 T20261 T20259 arg1Of promoter,the
R16243 T20261 T20260 arg1Of promoter,A3G
R16244 T20265 T20262 arg1Of substitutions,The
R16245 T20265 T20263 arg1Of substitutions,two
R16246 T20265 T20264 arg1Of substitutions,G-to-T
R16247 T20265 T20266 arg2Of substitutions,introduced
R16248 T20265 T20277 arg1Of substitutions,are
R16249 T20265 T20278 arg2Of substitutions,specified
R16250 T20266 T20267 arg1Of introduced,into
R16251 T20269 T20267 arg2Of GC-box,into
R16252 T20269 T20268 arg1Of GC-box,the
R16253 T20269 T20270 arg1Of GC-box,of
R16254 T20273 T20270 arg2Of fragment,of
R16255 T20273 T20271 arg1Of fragment,the
R16256 T20273 T20272 arg1Of fragment,180 bp
R16257 T20273 T20274 arg1Of fragment,(
R16258 T20275 T20274 arg2Of 180mut,(
R16259 T20276 T20274 arg3Of ),(
R16260 T20278 T20277 arg2Of specified,are
R16261 T20280 T20279 arg2Of 48 h,After
R16262 T20282 T20283 arg1Of cells,were
R16263 T20282 T20284 arg2Of cells,harvested
R16264 T20284 T20279 arg1Of harvested,After
R16265 T20284 T20281 arg1Of harvested,","
R16266 T20284 T20283 arg2Of harvested,were
R16267 T20284 T20285 arg1Of harvested,for
R16268 T20287 T20285 arg2Of assay,for
R16269 T20287 T20286 arg1Of assay,luciferase
R16270 T20290 T20288 arg1Of activities,Firefly
R16271 T20290 T20289 arg1Of activities,luciferase
R16272 T20290 T20291 arg1Of activities,were
R16273 T20290 T20292 arg2Of activities,normalized
R16274 T20292 T20291 arg2Of normalized,were
R16275 T20292 T20293 arg1Of normalized,to
R16276 T20297 T20293 arg2Of activities,to
R16277 T20297 T20294 arg2Of activities,coexpressed
R16278 T20297 T20295 arg1Of activities,renilla
R16279 T20297 T20296 arg1Of activities,luciferase
R16280 T20299 T20298 arg1Of values,Mean
R16281 T20299 T20300 arg1Of values,(
R16282 T20299 T20303 arg1Of values,of
R16283 T20299 T20310 arg1Of values,are
R16284 T20301 T20300 arg2Of ±SD,(
R16285 T20302 T20300 arg3Of ),(
R16286 T20306 T20303 arg2Of experiment,of
R16287 T20306 T20304 arg1Of experiment,a
R16288 T20306 T20305 arg1Of experiment,representative
R16289 T20306 T20307 arg2Of experiment,performed
R16290 T20307 T20308 arg1Of performed,in
R16291 T20309 T20308 arg2Of triplicate,in
R16292 T20311 T20310 arg2Of shown.,are
R16293 T20311 T20312 arg1Of shown.,(
R16294 T20311 T20334 modOf shown.,were
R16295 T20313 T20312 arg2Of B,(
R16296 T20314 T20312 arg3Of ),(
R16297 T20317 T20315 arg1Of plasmids,pGL3-Promoter
R16298 T20317 T20316 arg1Of plasmids,reporter
R16299 T20317 T20318 arg1Of plasmids,containing
R163 T192 T190 arg2Of inducible,was
R16300 T20317 T20329 arg1Of plasmids,upstream
R16301 T20317 T20334 arg1Of plasmids,were
R16302 T20317 T20335 arg2Of plasmids,transfected
R16303 T20318 T20324 arg1Of containing,(
R16304 T20321 T20322 arg1Of E1,or
R16305 T20322 T20318 arg2Of or,containing
R16306 T20322 T20319 arg1Of or,the
R16307 T20322 T20320 arg1Of or,regions
R16308 T20323 T20322 arg2Of E2,or
R16309 T20325 T20324 arg2Of see,(
R16310 T20326 T20325 arg2Of Figure,see
R16311 T20326 T20327 arg1Of Figure,1
R16312 T20328 T20324 arg3Of ),(
R16313 T20329 T20330 arg1Of upstream,of
R16314 T20333 T20330 arg2Of promoter,of
R16315 T20333 T20331 arg1Of promoter,the
R16316 T20333 T20332 arg1Of promoter,SV40
R16317 T20335 T20334 arg2Of transfected,were
R16318 T20335 T20336 arg1Of transfected,into
R16319 T20338 T20336 arg2Of cells,into
R16320 T20338 T20337 arg1Of cells,A3.01 T
R16321 T20341 T20339 arg1Of activities,Firefly
R16322 T20341 T20340 arg1Of activities,luciferase
R16323 T20341 T20342 arg1Of activities,after
R16324 T20341 T20344 arg1Of activities,were
R16325 T20341 T20345 arg2Of activities,normalized
R16326 T20343 T20342 arg2Of 48 h,after
R16327 T20345 T20344 arg2Of normalized,were
R16328 T20345 T20346 arg1Of normalized,to
R16329 T20350 T20346 arg2Of activities,to
R16330 T20350 T20347 arg2Of activities,coexpressed
R16331 T20350 T20348 arg1Of activities,renilla
R16332 T20350 T20349 arg1Of activities,luciferase
R16333 T20352 T20351 arg1Of values,Mean
R16334 T20352 T20353 arg1Of values,(
R16335 T20352 T20356 arg1Of values,of
R16336 T20352 T20363 arg1Of values,are
R16337 T20352 T20364 arg2Of values,shown
R16338 T20354 T20353 arg2Of ±SD,(
R16339 T20355 T20353 arg3Of ),(
R16340 T20359 T20356 arg2Of experiment,of
R16341 T20359 T20357 arg1Of experiment,a
R16342 T20359 T20358 arg1Of experiment,representative
R16343 T20359 T20360 arg2Of experiment,performed
R16344 T20360 T20361 arg1Of performed,in
R16345 T20362 T20361 arg2Of triplicate,in
R16346 T20364 T20363 arg2Of shown,are
R164 T192 T193 arg1Of inducible,by
R165 T195 T194 arg1Of stimulation,mitogenic
R16539 T20720 T20721 arg1Of Sp1,and
R16540 T20721 T20723 arg1Of and,bind
R16541 T20722 T20721 arg2Of Sp3,and
R16542 T20723 T20724 arg1Of bind,to
R16543 T20726 T20724 arg2Of GC-box,to
R16544 T20726 T20725 arg1Of GC-box,the
R16545 T20726 T20727 arg1Of GC-box,present
R16546 T20727 T20728 arg1Of present,in
R16547 T20731 T20728 arg2Of promoter.,in
R16548 T20731 T20729 arg1Of promoter.,the
R16549 T20731 T20730 arg1Of promoter.,A3G
R16550 T20731 T20732 arg1Of promoter.,(
R16551 T20731 T20740 modOf promoter.,were
R16552 T20731 T20768 arg1Of promoter.,of
R16553 T20731 T20772 arg1Of promoter.,(
R16554 T20733 T20732 arg2Of A,(
R16555 T20734 T20732 arg3Of ),(
R16556 T20736 T20735 arg1Of extracts,Nuclear
R16557 T20736 T20737 arg1Of extracts,of
R16558 T20736 T20740 arg1Of extracts,were
R16559 T20736 T20741 arg2Of extracts,incubated
R16560 T20739 T20737 arg2Of cells,of
R16561 T20739 T20738 arg1Of cells,A3.01 T
R16562 T20741 T20740 arg2Of incubated,were
R16563 T20741 T20742 arg1Of incubated,with
R16564 T20741 T20763 arg1Of incubated,(
R16565 T20748 T20743 arg1Of probe,a
R16566 T20748 T20744 arg1Of probe,32P-labeled
R16567 T20748 T20745 arg1Of probe,commercial
R16568 T20748 T20746 arg1Of probe,Sp1
R16569 T20748 T20747 arg1Of probe,oligonucleotide
R16570 T20748 T20749 arg1Of probe,(
R16571 T20748 T20752 arg1Of probe,or
R16572 T20750 T20749 arg2Of Sp1cons,(
R16573 T20751 T20749 arg3Of ),(
R16574 T20752 T20742 arg2Of or,with
R16575 T20754 T20752 arg2Of probes,or
R16576 T20754 T20753 arg2Of probes,labeled
R16577 T20754 T20755 arg1Of probes,homologous
R16578 T20755 T20756 arg1Of homologous,to
R16579 T20762 T20756 arg2Of region,to
R16580 T20762 T20757 arg1Of region,the
R16581 T20762 T20758 arg1Of region,unmodified
R16582 T20762 T20759 arg1Of region,or
R16583 T20762 T20760 arg2Of region,mutated
R16584 T20762 T20761 arg1Of region,E2
R16585 T20764 T20763 arg2Of see,(
R16586 T20765 T20764 arg2Of Figure,see
R16587 T20765 T20766 arg1Of Figure,1
R16588 T20767 T20763 arg3Of ),(
R16589 T20771 T20768 arg2Of promoter,of
R16590 T20771 T20769 arg1Of promoter,the
R16591 T20771 T20770 arg1Of promoter,A3G
R16592 T20773 T20774 arg1Of APO-Sp1/3,and
R16593 T20774 T20772 arg2Of and,(
R16594 T20775 T20774 arg2Of APO-Sp1/3mut,and
R16595 T20776 T20772 arg3Of ),(
R16596 T20778 T20777 arg1Of complexes,Protein–DNA
R16597 T20778 T20779 arg1Of complexes,were
R16598 T20778 T20780 arg2Of complexes,separated
R16599 T20778 T20785 arg2Of complexes,detected
R166 T195 T196 arg1Of stimulation,","
R16600 T20780 T20784 arg1Of separated,and
R16601 T20783 T20780 arg1Of electrophoresis,separated
R16602 T20783 T20781 arg2Of electrophoresis,by
R16603 T20783 T20782 arg1Of electrophoresis,polyacrylamide
R16604 T20784 T20779 arg2Of and,were
R16605 T20785 T20784 arg2Of detected,and
R16606 T20787 T20785 arg1Of autoradiography,detected
R16607 T20787 T20786 arg2Of autoradiography,by
R16608 T20788 T20789 arg1Of EMSA,was
R16609 T20788 T20790 arg2Of EMSA,performed
R16610 T20790 T20789 arg2Of performed,was
R16611 T20790 T20791 arg1Of performed,with
R16612 T20793 T20791 arg2Of 1-,with
R16613 T20793 T20792 arg1Of 1-,a
R16614 T20796 T20795 arg1Of molar,30-fold
R16615 T20797 T20794 arg2Of excess,or
R16616 T20797 T20796 arg1Of excess,molar
R16617 T20797 T20798 arg1Of excess,of
R16618 T20801 T20799 arg1Of probe,unlabeled
R16619 T20801 T20800 arg1Of probe,APO-Sp1/3
R16620 T20801 T20802 arg1Of probe,(
R16621 T20801 T20810 arg1Of probe,or
R16622 T20803 T20802 arg2Of competitor,(
R16623 T20803 T20804 arg1Of competitor,","
R16624 T20806 T20807 arg1Of 6,and
R16625 T20807 T20804 arg2Of and,","
R16626 T20807 T20805 arg1Of and,lanes
R16627 T20808 T20807 arg2Of 7,and
R16628 T20809 T20802 arg3Of ),(
R16629 T20810 T20798 arg2Of or,of
R16630 T20812 T20810 arg2Of probe,or
R16631 T20812 T20811 arg1Of probe,APO-Sp1/3mut
R16632 T20812 T20813 arg1Of probe,(
R16633 T20815 T20813 arg2Of mut.,(
R16634 T20815 T20814 arg1Of mut.,competitor
R16635 T20815 T20816 arg1Of mut.,","
R16636 T20818 T20819 arg1Of 12,and
R16637 T20819 T20816 arg2Of and,","
R16638 T20819 T20817 arg1Of and,lanes
R16639 T20820 T20819 arg2Of 13,and
R16640 T20821 T20813 arg3Of ),(
R16641 T20823 T20822 arg2Of (,.
R16642 T20824 T20822 arg3Of B,.
R16643 T20825 T20826 arg1Of ) Sp,1-
R16644 T20827 T20826 arg2Of and Sp3-spec,1-
R16645 T20828 T20822 arg1Of ific antib,.
R16646 T20828 T20825 arg1Of ific antib,) Sp
R16647 T20828 T20827 arg1Of ific antib,and Sp3-spec
R16648 T20828 T20829 arg1Of ific antib,odie
R16649 T20828 T20830 arg2Of ific antib,s wer
R16650 T20830 T20829 arg2Of s wer,odie
R16651 T20830 T20831 arg1Of s wer,e
R16652 T20834 T20831 arg2Of o the EMS,e
R16653 T20834 T20832 arg1Of o the EMS,add
R16654 T20834 T20833 arg1Of o the EMS,ed t
R16655 T20835 T20836 arg1Of A reactio,ns
R16656 T20838 T20836 arg2Of esulting i,ns
R16657 T20838 T20837 arg1Of esulting i,r
R16658 T20838 T20839 arg1Of esulting i,n
R16659 T20838 T20842 arg1Of esulting i,up
R16660 T20840 T20839 arg2Of a ,n
R16661 T20841 T20839 arg3Of s,n
R16662 T20846 T20842 arg2Of body–prot,up
R16663 T20846 T20843 arg1Of body–prot,ers
R16664 T20846 T20844 arg1Of body–prot,hift (ss)
R16665 T20846 T20845 arg1Of body–prot,of the respective anti
R16666 T20849 T20850 arg1Of i,g
R16667 T20850 T20852 arg1Of g,c
R16668 T20851 T20850 arg2Of o,g
R16669 T20852 T20854 arg1Of c,m
R16670 T20853 T20852 arg2Of o,c
R16671 T20854 T20856 arg1Of m,l
R16672 T20855 T20854 arg2Of p,m
R16673 T20856 T20847 arg2Of l,e
R16674 T20856 T20848 arg1Of l,in–ol
R16675 T20856 T20858 arg1Of l,e
R16676 T20857 T20856 arg2Of ex,l
R16677 T20859 T20858 arg2Of s ,e
R16678 T20860 T20847 arg3Of (,e
R16679 T20862 T20861 arg2Of a,l
R16680 T20863 T20861 arg3Of n,l
R16681 T20865 T20864 arg1Of ", 4, ",es 3
R16682 T20865 T20866 arg1Of ", 4, ","7, "
R16683 T20865 T20867 arg2Of ", 4, ","8, 11, 12"
R16684 T20867 T20866 arg2Of "8, 11, 12","7, "
R16685 T20867 T20868 arg1Of "8, 11, 12",). (
R16686 T20869 T20868 arg2Of C) ,). (
R16687 T20869 T20870 arg1Of C) ,ChIP
R16688 T20872 T20870 arg2Of as pe,ChIP
R16689 T20872 T20871 arg1Of as pe,assay w
R16690 T20873 T20874 arg1Of Immunoprecipitation,was
R16691 T20873 T20875 arg2Of Immunoprecipitation,performed
R16692 T20875 T20874 arg2Of performed,was
R16693 T20875 T20876 arg1Of performed,with
R16694 T20877 T20876 arg2Of antibodies,with
R16695 T20877 T20878 arg1Of antibodies,against
R16696 T20879 T20880 arg1Of Sp1,","
R16697 T20880 T20882 arg1Of ",",or
R16698 T20881 T20880 arg2Of Sp3,","
R16699 T20882 T20878 arg2Of or,against
R167 T196 T199 arg1Of ",",or
R16700 T20883 T20882 arg2Of actin,or
R16701 T20886 T20884 arg1Of pairs,PCR
R16702 T20886 T20885 arg1Of pairs,primer
R16703 T20886 T20887 arg1Of pairs,specific
R16704 T20886 T20904 arg1Of pairs,were
R16705 T20886 T20905 arg2Of pairs,used
R16706 T20887 T20888 arg1Of specific,for
R16707 T20891 T20889 arg1Of promoter,the
R16708 T20891 T20890 arg1Of promoter,A3G
R16709 T20891 T20892 arg1Of promoter,(
R16710 T20891 T20896 arg1Of promoter,or
R16711 T20894 T20892 arg2Of panel,(
R16712 T20894 T20893 arg1Of panel,upper
R16713 T20895 T20892 arg3Of ),(
R16714 T20896 T20888 arg2Of or,for
R16715 T20899 T20896 arg2Of gene,or
R16716 T20899 T20897 arg1Of gene,the
R16717 T20899 T20898 arg1Of gene,A3G
R16718 T20899 T20900 arg1Of gene,(
R16719 T20902 T20900 arg2Of panel,(
R16720 T20902 T20901 arg1Of panel,lower
R16721 T20903 T20900 arg3Of ),(
R16722 T20905 T20904 arg2Of used,were
R16723 T20908 T20906 arg2Of controls,As
R16724 T20908 T20907 arg1Of controls,positive
R16725 T20911 T20912 arg1Of sheared,and
R16726 T20913 T20912 arg2Of cross-linked,and
R16727 T20914 T20910 arg1Of DNA,the
R16728 T20914 T20911 arg1Of DNA,sheared
R16729 T20914 T20913 arg1Of DNA,cross-linked
R16730 T20914 T20915 arg1Of DNA,before
R16731 T20914 T20932 arg1Of DNA,was
R16732 T20914 T20933 arg2Of DNA,used
R16733 T20918 T20916 arg1Of step,the
R16734 T20918 T20917 arg1Of step,immunoprecipitation
R16735 T20918 T20919 arg1Of step,(
R16736 T20918 T20922 arg1Of step,or
R16737 T20920 T20919 arg2Of input,(
R16738 T20921 T20919 arg3Of ),(
R16739 T20922 T20915 arg2Of or,before
R16740 T20924 T20922 arg2Of plasmid,or
R16741 T20924 T20923 arg1Of plasmid,a
R16742 T20924 T20925 arg1Of plasmid,carrying
R16743 T20928 T20925 arg2Of sequence,carrying
R16744 T20928 T20926 arg1Of sequence,the
R16745 T20928 T20927 arg1Of sequence,target
R16746 T20928 T20929 arg1Of sequence,(
R16747 T20930 T20929 arg2Of plasmid,(
R16748 T20931 T20929 arg3Of ),(
R16749 T20933 T20906 arg1Of used,As
R16750 T20933 T20909 arg1Of used,","
R16751 T20933 T20932 arg2Of used,was
R16752 T20933 T20934 arg1Of used,as
R16753 T20935 T20934 arg2Of template,as
R168 T198 T196 arg2Of treatment,","
R169 T198 T197 arg1Of treatment,interferon
R170 T199 T193 arg2Of or,by
R17049 T21467 T21468 arg1Of Silencing,of
R17050 T21467 T21472 arg1Of Silencing,reduces
R17051 T21469 T21470 arg1Of Sp1,and
R17052 T21470 T21468 arg2Of and,of
R17053 T21471 T21470 arg2Of Sp3,and
R17054 T21475 T21472 arg2Of activity.,reduces
R17055 T21475 T21473 arg1Of activity.,A3G
R17056 T21475 T21474 arg1Of activity.,promoter
R17057 T21475 T21476 arg1Of activity.,(
R17058 T21475 T21481 modOf activity.,were
R17059 T21477 T21476 arg2Of A,(
R17060 T21478 T21476 arg3Of ),(
R17061 T21480 T21479 arg1Of cells,HeLa
R17062 T21480 T21481 arg1Of cells,were
R17063 T21480 T21482 arg2Of cells,transfected
R17064 T21482 T21481 arg2Of transfected,were
R17065 T21482 T21483 arg1Of transfected,with
R17066 T21484 T21485 arg1Of 150,and
R17067 T21485 T21483 arg2Of and,with
R17068 T21485 T21487 arg1Of and,of
R17069 T21486 T21485 arg2Of 300 ng,and
R17070 T21488 T21489 arg1Of unspecific,","
R17071 T21489 T21491 arg1Of ",",or
R17072 T21490 T21489 arg2Of Sp1-specific,","
R17073 T21492 T21491 arg2Of Sp3-specific,or
R17074 T21493 T21487 arg2Of siRNA,of
R17075 T21493 T21488 arg1Of siRNA,unspecific
R17076 T21493 T21490 arg1Of siRNA,Sp1-specific
R17077 T21493 T21492 arg1Of siRNA,Sp3-specific
R17078 T21495 T21494 arg2Of 48 h,After
R17079 T21497 T21498 arg1Of cells,were
R17080 T21497 T21499 arg2Of cells,harvested
R17081 T21499 T21498 arg2Of harvested,were
R17082 T21499 T21500 arg1Of harvested,and
R17083 T21500 T21494 arg1Of and,After
R17084 T21500 T21496 arg1Of and,","
R17085 T21501 T21502 arg1Of Sp1,and
R17086 T21503 T21502 arg2Of Sp3,and
R17087 T21504 T21501 arg1Of proteins,Sp1
R17088 T21504 T21503 arg1Of proteins,Sp3
R17089 T21504 T21505 arg1Of proteins,were
R17090 T21504 T21506 arg2Of proteins,detected
R17091 T21506 T21500 arg2Of detected,and
R17092 T21506 T21505 arg2Of detected,were
R17093 T21510 T21506 arg1Of analysis,detected
R17094 T21510 T21507 arg2Of analysis,by
R17095 T21510 T21508 arg1Of analysis,western
R17096 T21510 T21509 arg1Of analysis,blot
R17097 T21512 T21511 arg2Of loading,As
R17098 T21513 T21512 arg2Of control,loading
R17099 T21516 T21512 arg1Of levels,loading
R171 T199 T201 arg1Of or,of
R17100 T21516 T21515 arg1Of levels,protein
R17101 T21516 T21517 arg1Of levels,of
R17102 T21516 T21519 arg1Of levels,are
R17103 T21518 T21517 arg2Of tubulin,of
R17104 T21519 T21511 arg1Of are,As
R17105 T21519 T21514 arg1Of are,","
R17106 T21520 T21519 arg2Of shown.,are
R17107 T21520 T21521 arg1Of shown.,(
R17108 T21520 T21526 modOf shown.,were
R17109 T21522 T21521 arg2Of B,(
R17110 T21523 T21521 arg3Of ),(
R17111 T21525 T21524 arg1Of cells,HeLa
R17112 T21525 T21526 arg1Of cells,were
R17113 T21525 T21527 arg2Of cells,cotransfected
R17114 T21527 T21526 arg2Of cotransfected,were
R17115 T21527 T21528 arg1Of cotransfected,with
R17116 T21530 T21529 arg1Of plasmid,reporter
R17117 T21530 T21531 arg1Of plasmid,pGL3-Basic
R17118 T21530 T21532 arg1Of plasmid,containing
R17119 T21530 T21540 arg1Of plasmid,and
R17120 T21533 T21534 arg1Of 180,or
R17121 T21534 T21532 arg2Of or,containing
R17122 T21534 T21536 arg1Of or,of
R17123 T21535 T21534 arg2Of 150 bp,or
R17124 T21539 T21536 arg2Of promoter,of
R17125 T21539 T21537 arg1Of promoter,the
R17126 T21539 T21538 arg1Of promoter,A3G
R17127 T21540 T21528 arg2Of and,with
R17128 T21541 T21540 arg2Of siRNA,and
R17129 T21543 T21542 arg2Of nanogram,Hundred
R17130 T21543 T21544 arg1Of nanogram,of
R17131 T21543 T21575 arg1Of nanogram,were
R17132 T21543 T21576 arg2Of nanogram,used
R17133 T21546 T21545 arg1Of siRNA,unspecific
R17134 T21546 T21547 arg1Of siRNA,(
R17135 T21546 T21550 arg1Of siRNA,","
R17136 T21548 T21547 arg2Of control,(
R17137 T21549 T21547 arg3Of ),(
R17138 T21550 T21556 arg1Of ",",","
R17139 T21552 T21550 arg2Of siRNA,","
R17140 T21552 T21551 arg1Of siRNA,Sp1-specific
R17141 T21552 T21553 arg1Of siRNA,(
R17142 T21554 T21553 arg2Of Sp1,(
R17143 T21555 T21553 arg3Of ),(
R17144 T21556 T21562 arg1Of ",",or
R17145 T21558 T21556 arg2Of siRNA,","
R17146 T21558 T21557 arg1Of siRNA,Sp3-specific
R17147 T21558 T21559 arg1Of siRNA,(
R17148 T21560 T21559 arg2Of Sp3,(
R17149 T21561 T21559 arg3Of ),(
R17150 T21562 T21544 arg2Of or,of
R17151 T21564 T21562 arg2Of mixture,or
R17152 T21564 T21563 arg1Of mixture,a
R17153 T21564 T21565 arg1Of mixture,of
R17154 T21566 T21567 arg1Of 50 ng,Sp1-specific
R17155 T21566 T21568 arg1Of 50 ng,plus
R17156 T21569 T21568 arg2Of 50 ng,plus
R17157 T21571 T21565 arg2Of siRNA,of
R17158 T21571 T21566 arg1Of siRNA,50 ng
R17159 T21571 T21569 arg1Of siRNA,50 ng
R17160 T21571 T21570 arg1Of siRNA,Sp3-specific
R17161 T21571 T21572 arg1Of siRNA,(
R17162 T21573 T21572 arg2Of Sp1+Sp3,(
R17163 T21574 T21572 arg3Of ),(
R17164 T21576 T21575 arg2Of used,were
R17165 T21579 T21577 arg1Of activities,Firefly
R17166 T21579 T21578 arg1Of activities,luciferase
R17167 T21579 T21580 arg1Of activities,after
R17168 T21579 T21582 arg1Of activities,were
R17169 T21579 T21583 arg2Of activities,normalized
R17170 T21581 T21580 arg2Of 48 h,after
R17171 T21583 T21582 arg2Of normalized,were
R17172 T21583 T21584 arg1Of normalized,to
R17173 T21588 T21584 arg2Of activities,to
R17174 T21588 T21585 arg2Of activities,coexpressed
R17175 T21588 T21586 arg1Of activities,renilla
R17176 T21588 T21587 arg1Of activities,luciferase
R17177 T21590 T21589 arg1Of values,Mean
R17178 T21590 T21591 arg1Of values,(
R17179 T21590 T21594 arg1Of values,of
R17180 T21590 T21601 arg1Of values,are
R17181 T21590 T21602 arg2Of values,shown
R17182 T21592 T21591 arg2Of ±SD,(
R17183 T21593 T21591 arg3Of ),(
R17184 T21597 T21594 arg2Of experiment,of
R17185 T21597 T21595 arg1Of experiment,a
R17186 T21597 T21596 arg1Of experiment,representative
R17187 T21597 T21598 arg2Of experiment,performed
R17188 T21598 T21599 arg1Of performed,in
R17189 T21600 T21599 arg2Of triplicate,in
R17190 T21602 T21601 arg2Of shown,are
R172 T200 T199 arg2Of expression,or
R173 T203 T201 arg2Of proteins,of
R174 T203 T202 arg1Of proteins,HIV-1
R175 T206 T204 arg2Of series,Using
R176 T206 T205 arg1Of series,a
R177 T206 T207 arg1Of series,of
R178 T206 T212 arg1Of series,in
R179 T211 T207 arg2Of constructs,of
R180 T211 T208 arg1Of constructs,5′
R181 T211 T209 arg1Of constructs,deletion
R182 T211 T210 arg1Of constructs,promoter
R183 T215 T212 arg2Of assays,in
R184 T215 T213 arg1Of assays,luciferase
R185 T215 T214 arg1Of assays,reporter
R186 T217 T204 arg1Of we,Using
R1864 T2316 T2315 arg1Of culture,Cell
R1865 T2321 T2317 arg1Of lines,The
R1866 T2321 T2318 arg1Of lines,human
R1867 T2321 T2319 arg1Of lines,T
R1868 T2321 T2320 arg1Of lines,cell
R1869 T2322 T2323 arg1Of A3.01,and
R187 T217 T218 arg1Of we,identified
R1870 T2323 T2321 arg1Of and,lines
R1871 T2323 T2325 arg1Of and,(
R1872 T2323 T2330 arg1Of and,and
R1873 T2324 T2323 arg2Of PM1,and
R1874 T2326 T2325 arg2Of NIBSC,(
R1875 T2326 T2327 arg1Of NIBSC,","
R1876 T2326 T2328 arg1Of NIBSC,UK
R1877 T2329 T2325 arg3Of ),(
R1878 T2330 T2342 arg1Of and,were
R1879 T2330 T2343 arg2Of and,grown
R188 T218 T204 modOf identified,Using
R1880 T2336 T2330 arg2Of U937,and
R1881 T2336 T2331 arg1Of U937,the
R1882 T2336 T2332 arg1Of U937,human
R1883 T2336 T2333 arg1Of U937,myeloid
R1884 T2336 T2334 arg1Of U937,cell
R1885 T2336 T2335 arg1Of U937,line
R1886 T2336 T2337 arg1Of U937,(
R1887 T2338 T2337 arg2Of NIBSC,(
R1888 T2338 T2339 arg1Of NIBSC,","
R1889 T2338 T2340 arg1Of NIBSC,UK
R189 T218 T216 arg1Of identified,","
R1890 T2341 T2337 arg3Of ),(
R1891 T2343 T2342 arg2Of grown,were
R1892 T2343 T2344 arg1Of grown,in
R1893 T2348 T2344 arg2Of medium,in
R1894 T2348 T2345 arg1Of medium,complete
R1895 T2348 T2346 arg1Of medium,RPMI
R1896 T2348 T2347 arg1Of medium,1640
R1897 T2348 T2349 arg2Of medium,supplemented
R1898 T2349 T2350 arg1Of supplemented,with
R1899 T2351 T2352 arg1Of 10,%
R190 T221 T218 arg2Of region,identified
R1900 T2355 T2351 arg1Of serum,10
R1901 T2355 T2353 arg1Of serum,fetal
R1902 T2355 T2354 arg1Of serum,bovine
R1903 T2355 T2356 arg1Of serum,","
R1904 T2356 T2359 arg1Of ",",and
R1905 T2358 T2356 arg2Of l-glutamine,","
R1906 T2358 T2357 arg1Of l-glutamine,2 mM
R1907 T2359 T2350 arg2Of and,with
R1908 T2361 T2359 arg2Of penicillin–streptomycin,and
R1909 T2361 T2360 arg1Of penicillin–streptomycin,100 U/ml
R191 T221 T219 arg1Of region,a
R1910 T2366 T2362 arg1Of lines,The
R1911 T2366 T2363 arg1Of lines,human
R1912 T2366 T2364 arg1Of lines,hepatic
R1913 T2366 T2365 arg1Of lines,cell
R1914 T2367 T2368 arg1Of HepG2,and
R1915 T2368 T2366 arg1Of and,lines
R1916 T2368 T2370 arg1Of and,(
R1917 T2368 T2392 modOf and,were
R1918 T2368 T2399 arg1Of and,modified
R1919 T2369 T2368 arg2Of Huh7,and
R192 T221 T220 arg1Of region,180 bp
R1920 T2372 T2370 arg2Of provided,(
R1921 T2372 T2371 arg1Of provided,kindly
R1922 T2376 T2372 arg1Of Pietschmann,provided
R1923 T2376 T2373 arg2Of Pietschmann,by
R1924 T2376 T2374 arg1Of Pietschmann,Dr
R1925 T2376 T2375 arg1Of Pietschmann,Thomas
R1926 T2376 T2377 arg1Of Pietschmann,","
R1927 T2376 T2382 arg1Of Pietschmann,","
R1928 T2378 T2377 arg2Of Department,","
R1929 T2378 T2379 arg1Of Department,of
R193 T221 T222 arg1Of region,that
R1930 T2381 T2379 arg2Of Virology,of
R1931 T2381 T2380 arg1Of Virology,Molecular
R1932 T2383 T2382 arg2Of University,","
R1933 T2383 T2384 arg1Of University,of
R1934 T2385 T2384 arg2Of Heidelberg,of
R1935 T2386 T2370 arg3Of ),(
R1936 T2389 T2387 arg1Of as,as
R1937 T2389 T2388 arg1Of as,well
R1938 T2391 T2389 arg1Of cells,as
R1939 T2391 T2390 arg1Of cells,HeLa
R194 T221 T223 arg1Of region,was
R1940 T2391 T2392 arg1Of cells,were
R1941 T2391 T2393 arg2Of cells,maintained
R1942 T2393 T2392 arg2Of maintained,were
R1943 T2393 T2394 arg1Of maintained,in
R1944 T2395 T2396 arg2Of Dulbecco,'s
R1945 T2398 T2394 arg2Of glucose,in
R1946 T2398 T2396 arg1Of glucose,'s
R1947 T2398 T2397 arg1Of glucose,high
R1948 T2400 T2401 arg2Of Eagle,'s
R1949 T2402 T2399 arg2Of medium,modified
R195 T221 T224 arg1Of region,sufficient
R1950 T2402 T2401 arg1Of medium,'s
R1951 T2402 T2403 arg1Of medium,(
R1952 T2402 T2406 arg2Of medium,supplemented
R1953 T2404 T2403 arg2Of DMEM,(
R1954 T2405 T2403 arg3Of ),(
R1955 T2406 T2407 arg1Of supplemented,with
R1956 T2408 T2409 arg1Of 10,%
R1957 T2412 T2408 arg1Of serum,10
R1958 T2412 T2410 arg1Of serum,fetal
R1959 T2412 T2411 arg1Of serum,bovine
R196 T224 T223 arg2Of sufficient,was
R1960 T2412 T2413 arg1Of serum,","
R1961 T2413 T2416 arg1Of ",",and
R1962 T2415 T2413 arg2Of l-glutamine,","
R1963 T2415 T2414 arg1Of l-glutamine,2 mM
R1964 T2416 T2407 arg2Of and,with
R1965 T2418 T2416 arg2Of penicillin–streptomycin,and
R1966 T2418 T2417 arg1Of penicillin–streptomycin,100 U/ml
R1967 T2420 T2419 arg1Of lines,Cells
R1968 T2420 T2421 arg1Of lines,were
R1969 T2420 T2422 arg2Of lines,incubated
R197 T224 T225 arg1Of sufficient,for
R1970 T2420 T2434 arg2Of lines,passaged
R1971 T2420 T2435 arg1Of lines,using
R1972 T2422 T2423 arg1Of incubated,at
R1973 T2422 T2433 arg1Of incubated,and
R1974 T2424 T2423 arg2Of 37°C,at
R1975 T2424 T2425 arg1Of 37°C,with
R1976 T2426 T2427 arg1Of 100,%
R1977 T2428 T2425 arg2Of humidity,with
R1978 T2428 T2426 arg1Of humidity,100
R1979 T2428 T2429 arg1Of humidity,in
R198 T228 T225 arg2Of activity,for
R1980 T2430 T2431 arg1Of 5–7,%
R1981 T2432 T2429 arg2Of CO2,in
R1982 T2432 T2430 arg1Of CO2,5–7
R1983 T2433 T2421 arg2Of and,were
R1984 T2434 T2433 arg2Of passaged,and
R1985 T2435 T2434 arg3Of using,passaged
R1986 T2439 T2435 arg2Of techniques,using
R1987 T2439 T2436 arg1Of techniques,standard
R1988 T2439 T2437 arg1Of techniques,cell
R1989 T2439 T2438 arg1Of techniques,culture
R199 T228 T226 arg1Of activity,full
R200 T228 T227 arg1Of activity,promoter
R201 T230 T229 arg1Of activity,Transcriptional
R202 T230 T231 arg1Of activity,of
R203 T230 T236 arg1Of activity,was
R204 T230 T237 arg1Of activity,dependent
R205 T230 T255 arg1Of activity,was
R206 T230 T256 arg2Of activity,abolished
R207 T235 T231 arg2Of promoter,of
R208 T235 T232 arg1Of promoter,this
R209 T235 T233 arg1Of promoter,A3G
R210 T235 T234 arg1Of promoter,core
R211 T236 T254 arg1Of was,and
R212 T237 T236 arg2Of dependent,was
R213 T237 T238 arg1Of dependent,on
R214 T240 T238 arg2Of GC-box,on
R215 T240 T239 arg1Of GC-box,a
R216 T240 T241 arg1Of GC-box,(
R217 T242 T241 arg2Of located,(
R218 T242 T243 arg1Of located,at
R219 T242 T247 arg1Of located,to
R220 T245 T243 arg2Of −87/−78,at
R221 T245 T244 arg1Of −87/−78,position
R222 T247 T246 arg1Of to,relative
R223 T252 T247 arg2Of site,to
R224 T252 T248 arg1Of site,the
R225 T252 T249 arg1Of site,major
R226 T252 T250 arg1Of site,transcriptional
R227 T252 T251 arg1Of site,start
R228 T253 T241 arg3Of ),(
R229 T256 T254 arg2Of abolished,and
R230 T256 T255 arg2Of abolished,was
R231 T256 T257 arg1Of abolished,after
R232 T258 T257 arg2Of mutation,after
R233 T258 T259 arg1Of mutation,of
R234 T262 T259 arg2Of element,of
R235 T262 T260 arg1Of element,this
R236 T262 T261 arg1Of element,DNA
R237 T266 T263 arg1Of assays,Electrophoretic
R238 T266 T264 arg1Of assays,mobility
R239 T266 T265 arg1Of assays,shift
R240 T266 T267 arg1Of assays,and
R241 T267 T271 arg1Of and,demonstrated
R242 T270 T267 arg2Of assays,and
R243 T270 T268 arg1Of assays,chromatin
R244 T270 T269 arg1Of assays,immunoprecipitation
R245 T275 T273 arg1Of GC-box,the
R246 T275 T274 arg2Of GC-box,identified
R247 T275 T276 arg1Of GC-box,represented
R248 T276 T271 arg2Of represented,demonstrated
R249 T276 T272 arg1Of represented,that
R250 T279 T276 arg2Of site,represented
R251 T279 T277 arg1Of site,a
R252 T279 T278 arg1Of site,binding
R253 T279 T280 arg1Of site,for
R254 T286 T281 arg1Of protein,the
R255 T286 T282 arg1Of protein,ubiquitous
R256 T286 T283 arg1Of protein,transcription
R257 T286 T284 arg1Of protein,factors
R258 T286 T285 arg1Of protein,specificity
R259 T286 T287 arg1Of protein,(
R260 T286 T290 arg1Of protein,1
R261 T286 T291 arg1Of protein,and
R262 T288 T287 arg2Of Sp,(
R263 T289 T287 arg3Of ),(
R264 T291 T280 arg2Of and,for
R265 T292 T291 arg2Of Sp3,and
R3145 T3871 T3870 arg1Of amplification,5′-Rapid
R3146 T3871 T3872 arg1Of amplification,of
R3147 T3871 T3874 arg1Of amplification,ends
R3148 T3873 T3872 arg2Of cDNA,of
R3149 T3875 T3874 arg2Of analysis,ends
R3150 T3875 T3876 arg1Of analysis,(
R3151 T3877 T3876 arg2Of RACE,(
R3152 T3878 T3876 arg3Of ),(
R3153 T3880 T3879 arg1Of RNA,Total
R3154 T3880 T3881 arg1Of RNA,was
R3155 T3880 T3882 arg2Of RNA,isolated
R3156 T3882 T3881 arg2Of isolated,was
R3157 T3882 T3883 arg1Of isolated,from
R3158 T3885 T3883 arg2Of cells,from
R3159 T3885 T3884 arg1Of cells,A3.01 T
R3160 T3886 T3882 arg3Of using,isolated
R3161 T3889 T3886 arg2Of kit,using
R3162 T3889 T3887 arg1Of kit,RNeasy
R3163 T3889 T3888 arg1Of kit,mini
R3164 T3889 T3890 arg1Of kit,(
R3165 T3891 T3890 arg2Of Qiagen,(
R3166 T3892 T3890 arg3Of ),(
R3167 T3896 T3893 arg1Of sites,The
R3168 T3896 T3894 arg1Of sites,transcriptional
R3169 T3896 T3895 arg1Of sites,start
R3170 T3896 T3897 arg1Of sites,of
R3171 T3896 T3899 arg1Of sites,were
R3172 T3896 T3900 arg2Of sites,identified
R3173 T3898 T3897 arg2Of A3G,of
R3174 T3900 T3899 arg2Of identified,were
R3175 T3901 T3900 arg3Of using,identified
R3176 T3901 T3909 arg1Of using,(
R3177 T3901 T3912 arg1Of using,according
R3178 T3905 T3901 arg2Of Kit,using
R3179 T3905 T3902 arg1Of Kit,the
R3180 T3905 T3903 arg1Of Kit,5′/3′
R3181 T3905 T3904 arg1Of Kit,RACE
R3182 T3905 T3906 arg1Of Kit,","
R3183 T3908 T3906 arg2Of Generation,","
R3184 T3908 T3907 arg1Of Generation,2nd
R3185 T3910 T3909 arg2Of Roche,(
R3186 T3911 T3909 arg3Of ),(
R3187 T3913 T3912 arg2Of to,according
R3188 T3915 T3914 arg1Of manufacturer,the
R3189 T3915 T3916 arg2Of manufacturer,'s
R3190 T3917 T3913 arg2Of instructions,to
R3191 T3917 T3916 arg1Of instructions,'s
R3192 T3920 T3918 arg1Of primers,The
R3193 T3920 T3919 arg1Of primers,following
R3194 T3920 T3921 arg1Of primers,were
R3195 T3920 T3922 arg2Of primers,used
R3196 T3922 T3921 arg2Of used,were
R3197 T3922 T3923 arg1Of used,:
R3198 T3922 T3924 arg1Of used,RACE-APO3G1
R3199 T3922 T3928 arg1Of used,for
R3200 T3922 T3945 arg1Of used,for
R3201 T3924 T3925 arg1Of RACE-APO3G1,(
R3202 T3926 T3925 arg2Of 5′-TATCCCTTGTACACTTTGT-3′,(
R3203 T3927 T3925 arg3Of ),(
R3204 T3930 T3929 arg1Of synthesis,cDNA
R3205 T3930 T3931 arg1Of synthesis,","
R3206 T3931 T3940 arg1Of ",",and
R3207 T3932 T3931 arg2Of RACE-APO3G2,","
R3208 T3932 T3933 arg1Of RACE-APO3G2,(
R3209 T3932 T3936 arg1Of RACE-APO3G2,for
R3210 T3934 T3933 arg2Of 5′-CATACTCCTGGTCACGAT-3′,(
R3211 T3935 T3933 arg3Of ),(
R3212 T3939 T3936 arg2Of PCR,for
R3213 T3939 T3937 arg1Of PCR,the
R3214 T3939 T3938 arg1Of PCR,first
R3215 T3940 T3928 arg2Of and,for
R3216 T3941 T3940 arg2Of RACE-APO3Gnest,and
R3217 T3941 T3942 arg1Of RACE-APO3Gnest,(
R3218 T3943 T3942 arg2Of 5′-GAATACACCTGGCCTCGAA-3′,(
R3219 T3944 T3942 arg3Of ),(
R3220 T3948 T3945 arg2Of PCR,for
R3221 T3948 T3946 arg1Of PCR,the
R3222 T3948 T3947 arg1Of PCR,nested
R3223 T3950 T3949 arg1Of products,Reaction
R3224 T3950 T3951 arg1Of products,were
R3225 T3950 T3952 arg2Of products,analyzed
R3226 T3950 T3958 arg2Of products,purified
R3227 T3950 T3968 arg1Of products,T/A-cloned
R3228 T3950 T3976 arg2Of products,sequenced
R3229 T3952 T3957 arg1Of analyzed,","
R3230 T3952 T3958 modOf analyzed,purified
R3231 T3952 T3959 modOf analyzed,using
R3232 T3952 T3967 arg1Of analyzed,","
R3233 T3952 T3968 modOf analyzed,T/A-cloned
R3234 T3952 T3975 arg1Of analyzed,and
R3235 T3956 T3952 arg1Of electrophoresis,analyzed
R3236 T3956 T3953 arg2Of electrophoresis,by
R3237 T3956 T3954 arg1Of electrophoresis,agarose
R3238 T3956 T3955 arg1Of electrophoresis,gel
R3239 T3963 T3959 arg2Of kit,using
R3240 T3963 T3960 arg1Of kit,QIAquick
R3241 T3963 T3961 arg1Of kit,gel
R3242 T3963 T3962 arg1Of kit,extraction
R3243 T3963 T3964 arg1Of kit,(
R3244 T3965 T3964 arg2Of Qiagen,(
R3245 T3966 T3964 arg3Of ),(
R3246 T3968 T3969 arg1Of T/A-cloned,into
R3247 T3971 T3969 arg2Of pCR4-TOPO,into
R3248 T3971 T3970 arg1Of pCR4-TOPO,vector
R3249 T3971 T3972 arg1Of pCR4-TOPO,(
R3250 T3973 T3972 arg2Of Invitrogen,(
R3251 T3974 T3972 arg3Of ),(
R3252 T3975 T3951 arg2Of and,were
R3253 T3976 T3975 arg2Of sequenced,and
R3389 T4178 T4177 arg1Of assay,Luciferase
R3390 T4181 T4179 arg2Of transfection,For
R3391 T4181 T4180 arg1Of transfection,transient
R3392 T4181 T4182 arg1Of transfection,of
R3393 T4183 T4184 arg1Of A3.01,and
R3394 T4185 T4184 arg2Of U937,and
R3395 T4186 T4182 arg2Of cells,of
R3396 T4186 T4183 arg1Of cells,A3.01
R3397 T4186 T4185 arg1Of cells,U937
R3398 T4190 T4188 arg1Of reagent,DMRIE-C
R3399 T4190 T4189 arg1Of reagent,transfection
R3400 T4190 T4191 arg1Of reagent,(
R3401 T4190 T4195 arg1Of reagent,was
R3402 T4190 T4196 arg2Of reagent,used
R3403 T4193 T4191 arg2Of Technologies,(
R3404 T4193 T4192 arg1Of Technologies,Life
R3405 T4194 T4191 arg3Of ),(
R3406 T4196 T4179 arg1Of used,For
R3407 T4196 T4187 arg1Of used,","
R3408 T4196 T4195 arg2Of used,was
R3409 T4196 T4197 arg1Of used,(
R3410 T4198 T4197 arg2Of 36,(
R3411 T4199 T4197 arg3Of ),(
R3412 T4200 T4201 arg1Of Cells,were
R3413 T4200 T4202 arg2Of Cells,seeded
R3414 T4202 T4201 arg2Of seeded,were
R3415 T4202 T4203 arg1Of seeded,in
R3416 T4207 T4203 arg2Of plates,in
R3417 T4207 T4204 arg1Of plates,6-well
R3418 T4207 T4205 arg1Of plates,tissue
R3419 T4207 T4206 arg1Of plates,culture
R3420 T4207 T4208 arg1Of plates,(
R3421 T4207 T4213 arg1Of plates,in
R3422 T4207 T4220 arg1Of plates,containing
R3423 T4209 T4208 arg2Of 5 × 105 cells,(
R3424 T4209 T4210 arg1Of 5 × 105 cells,per
R3425 T4211 T4210 arg2Of well,per
R3426 T4212 T4208 arg3Of ),(
R3427 T4215 T4213 arg2Of Opti-MEM,in
R3428 T4215 T4214 arg1Of Opti-MEM,1.5 ml
R3429 T4215 T4216 arg1Of Opti-MEM,(
R3430 T4218 T4216 arg2Of Technologies,(
R3431 T4218 T4217 arg1Of Technologies,Life
R3432 T4219 T4216 arg3Of ),(
R3433 T4220 T4229 arg1Of containing,After
R3434 T4225 T4221 arg1Of plasmid,0.5 µg
R3435 T4225 T4222 arg1Of plasmid,firefly
R3436 T4225 T4223 arg1Of plasmid,luciferase
R3437 T4225 T4224 arg1Of plasmid,reporter
R3438 T4225 T4226 arg1Of plasmid,and
R3439 T4226 T4220 arg2Of and,containing
R3440 T4228 T4226 arg2Of DMRIE-C.,and
R3441 T4228 T4227 arg1Of DMRIE-C.,3.5 µl
R3442 T4230 T4231 arg1Of 4–5 h,of
R3443 T4230 T4238 arg1Of 4–5 h,were
R3444 T4230 T4239 arg2Of 4–5 h,added
R3445 T4232 T4231 arg2Of incubation,of
R3446 T4232 T4233 arg1Of incubation,","
R3447 T4237 T4233 arg2Of medium,","
R3448 T4237 T4234 arg1Of medium,1.5 ml
R3449 T4237 T4235 arg1Of medium,complete
R3450 T4237 T4236 arg1Of medium,RPMI
R3451 T4239 T4229 arg2Of added,After
R3452 T4239 T4238 arg2Of added,were
R3453 T4240 T4241 arg1Of HepG2,and
R3454 T4242 T4241 arg2Of Huh7,and
R3455 T4244 T4240 arg1Of lines,HepG2
R3456 T4244 T4242 arg1Of lines,Huh7
R3457 T4244 T4243 arg1Of lines,cell
R3458 T4244 T4245 arg1Of lines,were
R3459 T4244 T4246 arg2Of lines,transfected
R3460 T4246 T4245 arg2Of transfected,were
R3461 T4246 T4247 modOf transfected,using
R3462 T4247 T4250 arg1Of using,as
R3463 T4249 T4247 arg2Of Plus,using
R3464 T4249 T4248 arg1Of Plus,LipofectAMINE
R3465 T4251 T4250 arg2Of recommended,as
R3466 T4254 T4251 arg1Of manufacturer,recommended
R3467 T4254 T4252 arg2Of manufacturer,by
R3468 T4254 T4253 arg1Of manufacturer,the
R3469 T4254 T4255 arg1Of manufacturer,(
R3470 T4257 T4255 arg2Of Technologies,(
R3471 T4257 T4256 arg1Of Technologies,Life
R3472 T4258 T4255 arg3Of ),(
R3473 T4263 T4261 arg1Of cells,exponential
R3474 T4263 T4262 arg1Of cells,growing
R3475 T4263 T4264 arg1Of cells,(
R3476 T4263 T4267 arg1Of cells,were
R3477 T4263 T4268 arg2Of cells,transfected
R3478 T4265 T4264 arg2Of 1.5 × 106,(
R3479 T4266 T4264 arg3Of ),(
R3480 T4268 T4259 arg1Of transfected,Briefly
R3481 T4268 T4260 arg1Of transfected,","
R3482 T4268 T4267 arg2Of transfected,were
R3483 T4268 T4269 arg1Of transfected,with
R3484 T4271 T4269 arg2Of LipofectAMINE,with
R3485 T4271 T4270 arg1Of LipofectAMINE,5 µl
R3486 T4271 T4272 arg1Of LipofectAMINE,","
R3487 T4275 T4273 arg1Of reagent,6 µl
R3488 T4275 T4274 arg1Of reagent,PLUS
R3489 T4275 T4276 arg1Of reagent,and
R3490 T4276 T4272 arg2Of and,","
R3491 T4276 T4283 arg1Of and,in
R3492 T4279 T4276 arg2Of amount,and
R3493 T4279 T4277 arg1Of amount,the
R3494 T4279 T4278 arg1Of amount,required
R3495 T4279 T4280 arg1Of amount,of
R3496 T4282 T4280 arg2Of DNA,of
R3497 T4282 T4281 arg1Of DNA,plasmid
R3498 T4286 T4283 arg2Of volume,in
R3499 T4286 T4284 arg1Of volume,a
R3500 T4286 T4285 arg1Of volume,final
R3501 T4286 T4287 arg1Of volume,of
R3502 T4289 T4287 arg2Of Opti-MEM,of
R3503 T4289 T4288 arg1Of Opti-MEM,1 ml
R3504 T4291 T4290 arg2Of 4 h,Following
R3505 T4291 T4292 arg1Of 4 h,of
R3506 T4293 T4292 arg2Of incubation,of
R3507 T4295 T4296 arg1Of cells,were
R3508 T4295 T4297 arg2Of cells,washed
R3509 T4297 T4296 arg2Of washed,were
R3510 T4297 T4298 arg1Of washed,in
R3511 T4297 T4300 arg1Of washed,and
R3512 T4299 T4298 arg2Of PBS,in
R3513 T4300 T4290 arg1Of and,Following
R3514 T4300 T4294 arg1Of and,","
R3515 T4301 T4302 arg1Of 3 ml,of
R3516 T4301 T4306 arg1Of 3 ml,were
R3517 T4301 T4307 arg2Of 3 ml,added
R3518 T4305 T4302 arg2Of medium,of
R3519 T4305 T4303 arg1Of medium,complete
R3520 T4305 T4304 arg1Of medium,DMEM
R3521 T4307 T4300 arg2Of added,and
R3522 T4307 T4306 arg2Of added,were
R3523 T4309 T4308 arg2Of cotransfection,For
R3524 T4309 T4310 arg1Of cotransfection,of
R3525 T4312 T4311 arg1Of plasmids,reporter
R3526 T4312 T4313 arg1Of plasmids,and
R3527 T4313 T4310 arg2Of and,of
R3528 T4313 T4315 arg1Of and,into
R3529 T4314 T4313 arg2Of siRNA,and
R3530 T4317 T4315 arg2Of cells,into
R3531 T4317 T4316 arg1Of cells,HeLa
R3532 T4321 T4319 arg1Of reagent,HiPerfect
R3533 T4321 T4320 arg1Of reagent,transfection
R3534 T4321 T4322 arg1Of reagent,(
R3535 T4321 T4325 arg1Of reagent,was
R3536 T4321 T4326 arg2Of reagent,used
R3537 T4323 T4322 arg2Of Qiagen,(
R3538 T4324 T4322 arg3Of ),(
R3539 T4326 T4308 arg1Of used,For
R3540 T4326 T4318 arg1Of used,","
R3541 T4326 T4325 arg2Of used,was
R3542 T4326 T4327 arg1Of used,according
R3543 T4326 T4333 arg1Of used,for
R3544 T4328 T4327 arg2Of to,according
R3545 T4330 T4329 arg1Of manufacturer,the
R3546 T4330 T4331 arg2Of manufacturer,'s
R3547 T4332 T4328 arg2Of protocol,to
R3548 T4332 T4331 arg1Of protocol,'s
R3549 T4334 T4333 arg2Of cotransfection,for
R3550 T4334 T4335 arg1Of cotransfection,of
R3551 T4334 T4338 arg1Of cotransfection,with
R3552 T4337 T4335 arg2Of cells,of
R3553 T4337 T4336 arg1Of cells,adherent
R3554 T4339 T4340 arg1Of siRNA,and
R3555 T4340 T4338 arg2Of and,with
R3556 T4342 T4340 arg2Of DNA,and
R3557 T4342 T4341 arg1Of DNA,plasmid
R3558 T4344 T4343 arg1Of days,Two
R3559 T4345 T4344 arg1Of after,days
R3560 T4346 T4345 arg2Of transfection,after
R3561 T4346 T4347 arg1Of transfection,of
R3562 T4351 T4347 arg2Of lines,of
R3563 T4351 T4348 arg1Of lines,the
R3564 T4351 T4349 arg1Of lines,respective
R3565 T4351 T4350 arg1Of lines,cell
R3566 T4353 T4354 arg1Of cells,were
R3567 T4353 T4355 arg2Of cells,harvested
R3568 T4355 T4354 arg2Of harvested,were
R3569 T4355 T4356 arg1Of harvested,in
R3570 T4355 T4375 arg1Of harvested,and
R3571 T4357 T4358 arg1Of 100 µl,(
R3572 T4357 T4362 arg1Of 100 µl,or
R3573 T4360 T4358 arg2Of cells,(
R3574 T4360 T4359 arg1Of cells,suspension
R3575 T4361 T4358 arg3Of ),(
R3576 T4362 T4356 arg2Of or,in
R3577 T4362 T4368 arg1Of or,of
R3578 T4363 T4362 arg2Of 300 µl,or
R3579 T4363 T4364 arg1Of 300 µl,(
R3580 T4366 T4364 arg2Of cells,(
R3581 T4366 T4365 arg1Of cells,adherent
R3582 T4367 T4364 arg3Of ),(
R3583 T4371 T4368 arg2Of Buffer,of
R3584 T4371 T4369 arg1Of Buffer,Passive
R3585 T4371 T4370 arg1Of Buffer,Lysis
R3586 T4371 T4372 arg1Of Buffer,(
R3587 T4373 T4372 arg2Of Promega,(
R3588 T4374 T4372 arg3Of ),(
R3589 T4375 T4345 arg1Of and,after
R3590 T4375 T4352 arg1Of and,","
R3591 T4377 T4376 arg1Of assay,luciferase
R3592 T4377 T4378 arg1Of assay,was
R3593 T4377 T4379 arg2Of assay,performed
R3594 T4379 T4375 arg2Of performed,and
R3595 T4379 T4378 arg2Of performed,was
R3596 T4380 T4379 arg3Of using,performed
R3597 T4380 T4389 arg1Of using,according
R3598 T4385 T4380 arg2Of System,using
R3599 T4385 T4381 arg1Of System,the
R3600 T4385 T4382 arg1Of System,Dual
R3601 T4385 T4383 arg1Of System,Luciferase
R3602 T4385 T4384 arg1Of System,Assay
R3603 T4385 T4386 arg1Of System,(
R3604 T4387 T4386 arg2Of Promega,(
R3605 T4388 T4386 arg3Of ),(
R3606 T4390 T4389 arg2Of to,according
R3607 T4392 T4391 arg1Of manufacturer,the
R3608 T4392 T4393 arg2Of manufacturer,'s
R3609 T4394 T4390 arg2Of instructions,to
R3610 T4394 T4393 arg1Of instructions,'s
R3611 T4398 T4395 arg2Of control,As
R3612 T4398 T4396 arg1Of control,an
R3613 T4398 T4397 arg1Of control,internal
R3614 T4400 T4401 arg1Of 50 ng,(
R3615 T4400 T4405 arg1Of 50 ng,or
R3616 T4403 T4401 arg2Of cells,(
R3617 T4403 T4402 arg1Of cells,adherent
R3618 T4404 T4401 arg3Of ),(
R3619 T4405 T4411 arg1Of or,of
R3620 T4405 T4432 arg1Of or,were
R3621 T4405 T4433 arg2Of or,normalized
R3622 T4405 T4435 arg1Of or,renilla
R3623 T4406 T4405 arg2Of 100 ng,or
R3624 T4406 T4407 arg1Of 100 ng,(
R3625 T4409 T4407 arg2Of cells,(
R3626 T4409 T4408 arg1Of cells,suspension
R3627 T4410 T4407 arg3Of ),(
R3628 T4413 T4411 arg2Of plasmid,of
R3629 T4413 T4412 arg1Of plasmid,ph-RG-TK
R3630 T4413 T4414 arg1Of plasmid,(
R3631 T4413 T4417 arg1Of plasmid,","
R3632 T4413 T4418 arg1Of plasmid,which
R3633 T4413 T4420 arg1Of plasmid,expresses
R3634 T4415 T4414 arg2Of Promega,(
R3635 T4416 T4414 arg3Of ),(
R3636 T4420 T4419 arg1Of expresses,constitutively
R3637 T4422 T4420 arg2Of luciferase,expresses
R3638 T4422 T4421 arg1Of luciferase,renilla
R3639 T4422 T4423 arg1Of luciferase,was
R3640 T4422 T4424 arg2Of luciferase,cotransfected
R3641 T4424 T4420 arg3Of cotransfected,expresses
R3642 T4424 T4423 arg2Of cotransfected,was
R3643 T4424 T4425 arg1Of cotransfected,in
R3644 T4427 T4428 arg1Of sample,and
R3645 T4429 T4428 arg2Of firefly,and
R3646 T4431 T4425 arg2Of activities,in
R3647 T4431 T4426 arg1Of activities,every
R3648 T4431 T4427 arg1Of activities,sample
R3649 T4431 T4429 arg1Of activities,firefly
R3650 T4431 T4430 arg1Of activities,luciferase
R3651 T4433 T4395 arg1Of normalized,As
R3652 T4433 T4399 arg1Of normalized,","
R3653 T4433 T4432 arg2Of normalized,were
R3654 T4435 T4433 arg3Of renilla,normalized
R3655 T4435 T4434 arg1Of renilla,to
R3656 T4437 T4435 arg2Of activities,renilla
R3657 T4437 T4436 arg1Of activities,luciferase
R3658 T4439 T4438 arg1Of values,Mean
R3659 T4439 T4440 arg1Of values,(
R3660 T4439 T4443 arg1Of values,of
R3661 T4439 T4450 arg1Of values,are
R3662 T4439 T4451 arg2Of values,shown
R3663 T4441 T4440 arg2Of ±SD,(
R3664 T4442 T4440 arg3Of ),(
R3665 T4446 T4443 arg2Of experiment,of
R3666 T4446 T4444 arg1Of experiment,a
R3667 T4446 T4445 arg1Of experiment,representative
R3668 T4446 T4447 arg2Of experiment,performed
R3669 T4447 T4448 arg1Of performed,in
R3670 T4449 T4448 arg2Of triplicate,in
R3671 T4451 T4450 arg2Of shown,are
R3672 T4451 T4452 arg1Of shown,in
R3673 T4454 T4452 arg2Of figures,in
R3674 T4454 T4453 arg1Of figures,the
R3675 T4456 T4455 arg2Of stimulation,For
R3676 T4456 T4457 arg1Of stimulation,of
R3677 T4458 T4457 arg2Of cells,of
R3678 T4461 T4460 arg1Of concentrations,final
R3679 T4461 T4462 arg1Of concentrations,of
R3680 T4461 T4477 arg1Of concentrations,were
R3681 T4461 T4478 arg2Of concentrations,applied
R3682 T4461 T4482 arg1Of concentrations,harvesting
R3683 T4464 T4463 arg1Of TPA,20 ng/ml
R3684 T4464 T4465 arg1Of TPA,(
R3685 T4464 T4468 arg1Of TPA,or
R3686 T4466 T4465 arg2Of Sigma,(
R3687 T4467 T4465 arg3Of ),(
R3688 T4468 T4462 arg2Of or,of
R3689 T4470 T4469 arg1Of IFN-α,30 ng/ml
R3690 T4470 T4471 arg1Of IFN-α,or
R3691 T4471 T4468 arg2Of or,or
R3692 T4473 T4471 arg2Of IFN-γ,or
R3693 T4473 T4472 arg1Of IFN-γ,30 ng/ml
R3694 T4473 T4474 arg1Of IFN-γ,(
R3695 T4475 T4474 arg2Of Tebu-Bio,(
R3696 T4476 T4474 arg3Of ),(
R3697 T4478 T4455 arg1Of applied,For
R3698 T4478 T4459 arg1Of applied,","
R3699 T4478 T4477 arg2Of applied,were
R3700 T4478 T4480 arg1Of applied,15 h
R3701 T4478 T4481 arg1Of applied,before
R3702 T4480 T4479 arg1Of 15 h,approximately
R3703 T4482 T4481 arg2Of harvesting,before
R3704 T4482 T4483 arg1Of harvesting,for
R3705 T4485 T4483 arg2Of assay,for
R3706 T4485 T4484 arg1Of assay,luciferase
R4059 T4989 T4986 arg1Of assay,Electrophoretic
R4060 T4989 T4987 arg1Of assay,mobility
R4061 T4989 T4988 arg1Of assay,shift
R4062 T4989 T4990 arg1Of assay,(
R4063 T4991 T4990 arg2Of EMSA,(
R4064 T4992 T4990 arg3Of ),(
R4065 T4994 T4993 arg2Of preparation,For
R4066 T4994 T4995 arg1Of preparation,of
R4067 T4997 T4995 arg2Of extracts,of
R4068 T4997 T4996 arg1Of extracts,nuclear
R4069 T5001 T4999 arg1Of cells,5 × 106
R4070 T5001 T5000 arg1Of cells,A3.01 T
R4071 T5001 T5002 arg1Of cells,were
R4072 T5001 T5003 arg2Of cells,washed
R4073 T5001 T5008 arg1Of cells,resuspended
R4074 T5003 T5002 arg2Of washed,were
R4075 T5003 T5004 arg1Of washed,in
R4076 T5003 T5007 arg1Of washed,and
R4077 T5006 T5004 arg2Of PBS,in
R4078 T5006 T5005 arg1Of PBS,cold
R4079 T5007 T4993 arg1Of and,For
R4080 T5007 T4998 arg1Of and,","
R4081 T5008 T5007 arg2Of resuspended,and
R4082 T5008 T5009 arg1Of resuspended,in
R4083 T5012 T5009 arg2Of A,in
R4084 T5012 T5010 arg1Of A,500 µl
R4085 T5012 T5011 arg1Of A,buffer
R4086 T5012 T5013 arg1Of A,(
R4087 T5016 T5014 arg1Of pH7.9,10 mM
R4088 T5016 T5015 arg1Of pH7.9,HEPES
R4089 T5016 T5017 arg1Of pH7.9,","
R4090 T5016 T5020 arg1Of pH7.9,","
R4091 T5016 T5023 arg1Of pH7.9,","
R4092 T5019 T5017 arg2Of KCl,","
R4093 T5019 T5018 arg1Of KCl,10 mM
R4094 T5022 T5020 arg2Of EDTA,","
R4095 T5022 T5021 arg1Of EDTA,0.1 mM
R4096 T5023 T5013 arg2Of ",",(
R4097 T5023 T5029 arg1Of ",",","
R4098 T5025 T5023 arg2Of EGTA,","
R4099 T5025 T5024 arg1Of EGTA,0.1 mM
R4100 T5025 T5026 arg1Of EGTA,","
R4101 T5028 T5026 arg2Of DTT,","
R4102 T5028 T5027 arg1Of DTT,1 mM
R4103 T5031 T5029 arg2Of PMSF,","
R4104 T5031 T5030 arg1Of PMSF,0.5 mM
R4105 T5032 T5013 arg3Of ),(
R4106 T5034 T5033 arg2Of incubation,After
R4107 T5034 T5035 arg1Of incubation,for
R4108 T5034 T5037 arg1Of incubation,on
R4109 T5036 T5035 arg2Of 15 min,for
R4110 T5038 T5037 arg2Of ice,on
R4111 T5041 T5040 arg1Of cells,swollen
R4112 T5041 T5042 arg1Of cells,were
R4113 T5041 T5043 arg2Of cells,pressed
R4114 T5041 T5054 arg2Of cells,centrifuged
R4115 T5043 T5045 arg1Of pressed,times
R4116 T5043 T5046 arg1Of pressed,through
R4117 T5043 T5053 arg1Of pressed,and
R4118 T5045 T5044 arg1Of times,10
R4119 T5048 T5046 arg2Of syringe,through
R4120 T5048 T5047 arg1Of syringe,a
R4121 T5048 T5049 arg1Of syringe,with
R4122 T5052 T5049 arg2Of needle,with
R4123 T5052 T5050 arg1Of needle,a
R4124 T5052 T5051 arg1Of needle,26G
R4125 T5053 T5033 arg1Of and,After
R4126 T5053 T5039 arg1Of and,","
R4127 T5053 T5042 arg2Of and,were
R4128 T5054 T5053 arg2Of centrifuged,and
R4129 T5054 T5055 arg1Of centrifuged,at
R4130 T5057 T5055 arg2Of r.p.m.,at
R4131 T5057 T5056 arg1Of r.p.m.,5000
R4132 T5057 T5058 arg1Of r.p.m.,for
R4133 T5059 T5058 arg2Of 5 min,for
R4134 T5060 T5061 arg1Of Pellets,contained
R4135 T5060 T5065 arg1Of Pellets,were
R4136 T5060 T5066 arg2Of Pellets,washed
R4137 T5060 T5074 arg1Of Pellets,resuspended
R4138 T5061 T5064 arg1Of contained,and
R4139 T5063 T5061 arg2Of nuclei,contained
R4140 T5063 T5062 arg1Of nuclei,the
R4141 T5064 T5073 arg1Of and,and
R4142 T5066 T5064 arg2Of washed,and
R4143 T5066 T5065 arg2Of washed,were
R4144 T5066 T5067 arg1Of washed,in
R4145 T5069 T5067 arg2Of A,in
R4146 T5069 T5068 arg1Of A,buffer
R4147 T5069 T5070 arg1Of A,for
R4148 T5072 T5070 arg2Of times,for
R4149 T5072 T5071 arg1Of times,two
R4150 T5074 T5073 arg2Of resuspended,and
R4151 T5074 T5075 arg1Of resuspended,in
R4152 T5078 T5075 arg2Of C,in
R4153 T5078 T5076 arg1Of C,50 µl
R4154 T5078 T5077 arg1Of C,buffer
R4155 T5078 T5079 arg1Of C,(
R4156 T5082 T5080 arg1Of pH,20 mM
R4157 T5082 T5081 arg1Of pH,HEPES
R4158 T5082 T5083 arg1Of pH,7.9
R4159 T5082 T5084 arg1Of pH,","
R4160 T5084 T5087 arg1Of ",",","
R4161 T5086 T5084 arg2Of NaCl,","
R4162 T5086 T5085 arg1Of NaCl,400 mM
R4163 T5087 T5090 arg1Of ",",","
R4164 T5089 T5087 arg2Of EDTA,","
R4165 T5089 T5088 arg1Of EDTA,1 mM
R4166 T5090 T5079 arg2Of ",",(
R4167 T5090 T5095 arg1Of ",",","
R4168 T5094 T5090 arg2Of DTT,","
R4169 T5094 T5091 arg1Of DTT,1 mM
R4170 T5094 T5092 arg1Of DTT,EGTA
R4171 T5094 T5093 arg1Of DTT,1 mM
R4172 T5097 T5095 arg2Of PMSF,","
R4173 T5097 T5096 arg1Of PMSF,1 mM
R4174 T5098 T5079 arg3Of ),(
R4175 T5100 T5099 arg2Of shaking,After
R4176 T5100 T5101 arg1Of shaking,for
R4177 T5100 T5109 arg1Of shaking,at
R4178 T5102 T5101 arg2Of 30 min,for
R4179 T5102 T5103 arg1Of 30 min,at
R4180 T5104 T5105 arg1Of 4°C,and
R4181 T5105 T5103 arg2Of and,at
R4182 T5105 T5107 arg1Of and,for
R4183 T5106 T5105 arg2Of centrifugation,and
R4184 T5108 T5107 arg2Of 10 min,for
R4185 T5111 T5110 arg1Of 000,13
R4186 T5112 T5109 arg2Of r.p.m.,at
R4187 T5112 T5111 arg1Of r.p.m.,000
R4188 T5114 T5100 arg1Of supernatants,shaking
R4189 T5114 T5115 arg1Of supernatants,were
R4190 T5114 T5116 arg2Of supernatants,used
R4191 T5116 T5099 arg1Of used,After
R4192 T5116 T5113 arg1Of used,","
R4193 T5116 T5115 arg2Of used,were
R4194 T5116 T5117 arg1Of used,as
R4195 T5119 T5117 arg2Of extracts,as
R4196 T5119 T5118 arg1Of extracts,nuclear
R4197 T5121 T5120 arg1Of probes,EMSA
R4198 T5121 T5122 arg1Of probes,were
R4199 T5121 T5123 arg2Of probes,generated
R42 T76 T77 arg1Of Sp1,and
R4200 T5123 T5122 arg2Of generated,were
R4201 T5123 T5124 arg1Of generated,by
R4202 T5123 T5130 arg1Of generated,:
R4203 T5123 T5131 arg1Of generated,APO-Sp1/3
R4204 T5123 T5145 arg1Of generated,according
R4205 T5125 T5124 arg2Of annealing,by
R4206 T5129 T5125 arg2Of oligonucleotides,annealing
R4207 T5129 T5126 arg1Of oligonucleotides,the
R4208 T5129 T5127 arg1Of oligonucleotides,following
R4209 T5129 T5128 arg1Of oligonucleotides,complementary
R4210 T5131 T5132 arg1Of APO-Sp1/3,","
R4211 T5131 T5139 arg1Of APO-Sp1/3,","
R4212 T5134 T5133 arg1Of CCAGCTGGGCGGGACCACCAGGGGAGGGGC-3′,5′-
R4213 T5134 T5135 arg1Of CCAGCTGGGCGGGACCACCAGGGGAGGGGC-3′,and
R4214 T5135 T5132 arg2Of and,","
R4215 T5136 T5137 arg1Of 5′-GCCCCTCCCCTGGTGGTCCCGCCCAGCTGG-3′,;
R4216 T5137 T5135 arg2Of ;,and
R4217 T5138 T5137 arg2Of APO-Sp1/3mut,;
R4218 T5140 T5141 arg1Of 5′-,CCAGCTGTTCGGGACCACCAGGGGAGGGGC-3′
R4219 T5140 T5142 arg1Of 5′-,and
R4220 T5143 T5142 arg2Of 5′-,and
R4221 T5144 T5139 arg2Of GCCCCTCCCCTGGTGGTCCCGAACAGCTGG-3′,","
R4222 T5144 T5140 arg1Of GCCCCTCCCCTGGTGGTCCCGAACAGCTGG-3′,5′-
R4223 T5144 T5143 arg1Of GCCCCTCCCCTGGTGGTCCCGAACAGCTGG-3′,5′-
R4224 T5146 T5145 arg2Of to,according
R4225 T5148 T5146 arg2Of procedures,to
R4226 T5148 T5147 arg1Of procedures,standard
R4227 T5149 T5150 arg1Of Nucleotides,differing
R4228 T5149 T5156 arg1Of Nucleotides,are
R4229 T5149 T5157 arg2Of Nucleotides,shown
R4230 T5150 T5151 arg1Of differing,from
R4231 T5155 T5151 arg2Of sequence,from
R4232 T5155 T5152 arg1Of sequence,the
R4233 T5155 T5153 arg1Of sequence,original
R4234 T5155 T5154 arg1Of sequence,promoter
R4235 T5157 T5156 arg2Of shown,are
R4236 T5157 T5158 arg1Of shown,in
R4237 T5160 T5158 arg2Of type,in
R4238 T5160 T5159 arg1Of type,bold
R4239 T5163 T5162 arg1Of available,commercially
R4240 T5165 T5161 arg1Of probe,A
R4241 T5165 T5163 arg1Of probe,available
R4242 T5165 T5164 arg1Of probe,Sp1
R4243 T5165 T5166 arg1Of probe,(
R4244 T5165 T5174 arg1Of probe,was
R4245 T5165 T5175 arg2Of probe,purchased
R4246 T5165 T5206 arg2Of probe,purified
R4247 T5167 T5166 arg2Of sc-2502,(
R4248 T5167 T5168 arg1Of sc-2502,","
R4249 T5167 T5169 arg2Of sc-2502,referred
R4250 T5169 T5170 arg1Of referred,to
R4251 T5169 T5171 arg1Of referred,as
R4252 T5172 T5171 arg2Of Sp1cons,as
R4253 T5173 T5166 arg3Of ),(
R4254 T5175 T5176 arg1Of purchased,from
R4255 T5175 T5186 modOf purchased,using
R4256 T5175 T5205 arg1Of purchased,and
R4257 T5179 T5177 arg1Of Biotechnology.,Santa
R4258 T5179 T5178 arg1Of Biotechnology.,Cruz
R4259 T5179 T5183 modOf Biotechnology.,were
R4260 T5182 T5180 arg1Of oligonucleotides,The
R4261 T5182 T5181 arg1Of oligonucleotides,double-stranded
R4262 T5182 T5183 arg1Of oligonucleotides,were
R4263 T5182 T5184 arg1Of oligonucleotides,5′
R4264 T5184 T5183 arg2Of 5′,were
R4265 T5185 T5176 arg2Of end-labeled,from
R4266 T5185 T5179 arg1Of end-labeled,Biotechnology.
R4267 T5189 T5187 arg1Of kinase,T4
R4268 T5189 T5188 arg1Of kinase,polynucleotide
R4269 T5189 T5190 arg1Of kinase,(
R4270 T5189 T5195 arg1Of kinase,and
R4271 T5193 T5190 arg2Of Biolabs,(
R4272 T5193 T5191 arg1Of Biolabs,New
R4273 T5193 T5192 arg1Of Biolabs,England
R4274 T5194 T5190 arg3Of ),(
R4275 T5195 T5186 arg2Of and,using
R4276 T5197 T5196 arg2Of γ-32P,[
R4277 T5198 T5196 arg3Of ],[
R4278 T5199 T5195 arg2Of ATP,and
R4279 T5199 T5196 arg1Of ATP,[
R4280 T5199 T5200 arg1Of ATP,(
R4281 T5201 T5200 arg2Of 3000 Ci/mmol,(
R4282 T5201 T5202 arg1Of 3000 Ci/mmol,","
R4283 T5203 T5202 arg2Of Amersham,","
R4284 T5204 T5200 arg3Of ),(
R4285 T5205 T5174 arg2Of and,was
R4286 T5206 T5205 arg2Of purified,and
R4287 T5206 T5207 arg1Of purified,by
R4288 T5208 T5207 arg2Of using,by
R4289 T5211 T5208 arg2Of columns,using
R4290 T5211 T5209 arg1Of columns,Nick
R4291 T5211 T5210 arg1Of columns,G50
R4292 T5211 T5212 arg1Of columns,(
R4293 T5213 T5212 arg2Of Amersham,(
R4294 T5214 T5212 arg3Of ),(
R4295 T5216 T5215 arg2Of EMSA,For
R4296 T5218 T5219 arg1Of 5 µg,of
R4297 T5218 T5222 arg1Of 5 µg,were
R4298 T5218 T5223 arg2Of 5 µg,preincubated
R4299 T5221 T5219 arg2Of proteins,of
R43 T77 T79 arg1Of and,regulate
R4300 T5221 T5220 arg1Of proteins,nuclear
R4301 T5223 T5215 arg1Of preincubated,For
R4302 T5223 T5217 arg1Of preincubated,","
R4303 T5223 T5222 arg2Of preincubated,were
R4304 T5223 T5224 arg1Of preincubated,on
R4305 T5225 T5224 arg2Of ice,on
R4306 T5225 T5226 arg1Of ice,with
R4307 T5227 T5226 arg2Of 2 µg,with
R4308 T5227 T5228 arg1Of 2 µg,of
R4309 T5229 T5230 arg1Of poly,(
R4310 T5229 T5233 arg1Of poly,(
R4311 T5229 T5236 arg1Of poly,as
R4312 T5229 T5240 arg1Of poly,and
R4313 T5231 T5230 arg2Of dI-dC,(
R4314 T5232 T5230 arg3Of ),(
R4315 T5234 T5233 arg2Of Roche,(
R4316 T5235 T5233 arg3Of ),(
R4317 T5239 T5236 arg2Of competitor,as
R4318 T5239 T5237 arg1Of competitor,an
R4319 T5239 T5238 arg1Of competitor,unspecific
R4320 T5240 T5228 arg2Of and,of
R4321 T5240 T5267 arg1Of and,for
R4322 T5241 T5240 arg2Of 1 µg,and
R4323 T5241 T5242 arg1Of 1 µg,of
R4324 T5241 T5246 arg1Of 1 µg,in
R4325 T5241 T5250 arg1Of 1 µg,(
R4326 T5245 T5242 arg2Of albumin,of
R4327 T5245 T5243 arg1Of albumin,bovine
R4328 T5245 T5244 arg1Of albumin,serum
R4329 T5249 T5246 arg2Of buffer,in
R4330 T5249 T5247 arg1Of buffer,band
R4331 T5249 T5248 arg1Of buffer,shift
R4332 T5252 T5251 arg1Of Tris,50 mM
R4333 T5252 T5253 arg1Of Tris,","
R4334 T5253 T5256 arg1Of ",",","
R4335 T5255 T5253 arg2Of KCl,","
R4336 T5255 T5254 arg1Of KCl,150 mM
R4337 T5256 T5259 arg1Of ",",","
R4338 T5258 T5256 arg2Of EDTA,","
R4339 T5258 T5257 arg1Of EDTA,5 mM
R4340 T5259 T5262 arg1Of ",",","
R4341 T5261 T5259 arg2Of dithiothreitol,","
R4342 T5261 T5260 arg1Of dithiothreitol,2.5 mM
R4343 T5262 T5250 arg2Of ",",(
R4344 T5263 T5264 arg1Of 20,%
R4345 T5265 T5262 arg2Of Ficoll,","
R4346 T5265 T5263 arg1Of Ficoll,20
R4347 T5266 T5250 arg3Of ),(
R4348 T5268 T5267 arg2Of 15 min,for
R4349 T5270 T5269 arg1Of oligonucleotides,32P-labeled
R4350 T5270 T5271 arg1Of oligonucleotides,(
R4351 T5270 T5275 arg1Of oligonucleotides,were
R4352 T5270 T5276 arg2Of oligonucleotides,added
R4353 T5270 T5290 arg2Of oligonucleotides,loaded
R4354 T5273 T5271 arg2Of 000 c.p.m.,(
R4355 T5273 T5272 arg1Of 000 c.p.m.,50
R4356 T5274 T5271 arg3Of ),(
R4357 T5276 T5277 arg1Of added,in
R4358 T5276 T5289 arg1Of added,and
R4359 T5280 T5277 arg2Of volume,in
R4360 T5280 T5278 arg1Of volume,a
R4361 T5280 T5279 arg1Of volume,total
R4362 T5280 T5281 arg1Of volume,of
R4363 T5280 T5283 arg1Of volume,","
R4364 T5280 T5284 arg2Of volume,incubated
R4365 T5282 T5281 arg2Of 20 µl,of
R4366 T5284 T5285 arg1Of incubated,on
R4367 T5286 T5285 arg2Of ice,on
R4368 T5286 T5287 arg1Of ice,for
R4369 T5288 T5287 arg2Of 20 min,for
R4370 T5289 T5275 arg2Of and,were
R4371 T5290 T5289 arg2Of loaded,and
R4372 T5290 T5291 arg1Of loaded,onto
R4373 T5292 T5293 arg1Of 5,%
R4374 T5296 T5291 arg2Of gels,onto
R4375 T5296 T5292 arg1Of gels,5
R4376 T5296 T5294 arg1Of gels,native
R4377 T5296 T5295 arg1Of gels,polyacrylamide
R4378 T5296 T5297 arg1Of gels,in
R4379 T5299 T5297 arg2Of buffer,in
R4380 T5299 T5298 arg1Of buffer,0.5×Tris-borate-EDTA
R4381 T5301 T5300 arg2Of fractionation,Upon
R4382 T5303 T5304 arg1Of gels,were
R4383 T5303 T5305 arg2Of gels,dried
R4384 T5303 T5307 arg2Of gels,exposed
R4385 T5305 T5306 arg1Of dried,and
R4386 T5306 T5300 arg1Of and,Upon
R4387 T5306 T5302 arg1Of and,","
R4388 T5306 T5304 arg2Of and,were
R4389 T5307 T5306 arg2Of exposed,and
R4390 T5307 T5308 arg1Of exposed,for
R4391 T5309 T5308 arg2Of autoradiography,for
R4392 T5312 T5310 arg2Of experiments,For
R4393 T5312 T5311 arg1Of experiments,competition
R4394 T5314 T5315 arg1Of 1-,or
R4395 T5317 T5315 arg2Of molar,or
R4396 T5317 T5316 arg1Of molar,30-fold
R4397 T5318 T5314 arg1Of excess,1-
R4398 T5318 T5317 arg1Of excess,molar
R4399 T5318 T5319 arg1Of excess,of
R44 T78 T77 arg2Of Sp3,and
R4400 T5318 T5326 arg1Of excess,was
R4401 T5318 T5327 arg2Of excess,added
R4402 T5322 T5323 arg1Of APO-Sp1/3,or
R4403 T5324 T5323 arg2Of APO-Sp1/3mut,or
R4404 T5325 T5319 arg2Of oligonucleotides,of
R4405 T5325 T5320 arg1Of oligonucleotides,the
R4406 T5325 T5321 arg1Of oligonucleotides,unlabeled
R4407 T5325 T5322 arg1Of oligonucleotides,APO-Sp1/3
R4408 T5325 T5324 arg1Of oligonucleotides,APO-Sp1/3mut
R4409 T5327 T5310 arg1Of added,For
R4410 T5327 T5313 arg1Of added,","
R4411 T5327 T5326 arg2Of added,was
R4412 T5327 T5328 arg1Of added,to
R4413 T5331 T5328 arg2Of mixture,to
R4414 T5331 T5329 arg1Of mixture,the
R4415 T5331 T5330 arg1Of mixture,preincubation
R4416 T5334 T5332 arg2Of experiments,For
R4417 T5334 T5333 arg1Of experiments,supershift
R4418 T5338 T5336 arg1Of antibody,2 µg
R4419 T5338 T5337 arg1Of antibody,Sp1
R4420 T5338 T5339 arg1Of antibody,(
R4421 T5338 T5346 arg1Of antibody,or
R4422 T5340 T5339 arg2Of sc-59x,(
R4423 T5340 T5341 arg1Of sc-59x,","
R4424 T5344 T5341 arg2Of Biotechnology,","
R4425 T5344 T5342 arg1Of Biotechnology,Santa
R4426 T5344 T5343 arg1Of Biotechnology,Cruz
R4427 T5345 T5339 arg3Of ),(
R4428 T5346 T5356 arg1Of or,were
R4429 T5346 T5357 arg2Of or,added
R4430 T5348 T5346 arg2Of antibody,or
R4431 T5348 T5347 arg1Of antibody,Sp3
R4432 T5348 T5349 arg1Of antibody,(
R4433 T5350 T5349 arg2Of sc-644x,(
R4434 T5350 T5351 arg1Of sc-644x,","
R4435 T5354 T5351 arg2Of Biotechnology,","
R4436 T5354 T5352 arg1Of Biotechnology,Santa
R4437 T5354 T5353 arg1Of Biotechnology,Cruz
R4438 T5355 T5349 arg3Of ),(
R4439 T5357 T5356 arg2Of added,were
R4440 T5357 T5358 arg1Of added,to
R4441 T5357 T5362 arg1Of added,and
R4442 T5361 T5358 arg2Of mixture,to
R4443 T5361 T5359 arg1Of mixture,the
R4444 T5361 T5360 arg1Of mixture,preincubation
R4445 T5362 T5332 arg1Of and,For
R4446 T5362 T5335 arg1Of and,","
R4447 T5364 T5363 arg1Of time,preincubation
R4448 T5364 T5365 arg1Of time,was
R4449 T5364 T5366 arg2Of time,extended
R4450 T5364 T5368 arg1Of time,30 min
R4451 T5366 T5362 arg2Of extended,and
R4452 T5366 T5365 arg2Of extended,was
R4453 T5368 T5366 arg3Of 30 min,extended
R4454 T5368 T5367 arg1Of 30 min,to
R45 T81 T79 arg2Of transcription,regulate
R46 T81 T80 arg1Of transcription,basal
R47 T81 T82 arg1Of transcription,of
R48 T86 T82 arg2Of gene,of
R49 T86 T83 arg1Of gene,the
R4915 T5975 T5974 arg1Of immunoprecipitation,Chromatin
R4916 T5975 T5976 arg1Of immunoprecipitation,(
R4917 T5977 T5976 arg2Of ChIP,(
R4918 T5978 T5976 arg3Of ),(
R4919 T5979 T5975 arg1Of assay,immunoprecipitation
R4920 T5981 T5980 arg1Of cells,A3.01
R4921 T5981 T5982 arg1Of cells,were
R4922 T5981 T5983 arg2Of cells,treated
R4923 T5983 T5982 arg2Of treated,were
R4924 T5983 T5984 arg1Of treated,with
R4925 T5985 T5984 arg2Of RPMI,with
R4926 T5987 T5986 arg1Of medium,culture
R4927 T5987 T5988 arg1Of medium,containing
R4928 T5987 T5994 arg1Of medium,at
R4929 T5987 T5997 arg1Of medium,were
R4930 T5987 T5998 arg2Of medium,washed
R4931 T5987 T6004 arg2Of medium,incubated
R4932 T5989 T5990 arg1Of 1,%
R4933 T5991 T5988 arg2Of formaldehyde,containing
R4934 T5991 T5989 arg1Of formaldehyde,1
R4935 T5991 T5992 arg1Of formaldehyde,for
R4936 T5993 T5992 arg2Of 10 min.,for
R4937 T5996 T5994 arg2Of Cells,at
R4938 T5996 T5995 arg1Of Cells,37°C.
R4939 T5998 T5999 arg1Of washed,twice
R4940 T5998 T6000 arg1Of washed,with
R4941 T5998 T6003 arg1Of washed,and
R4942 T6002 T6000 arg2Of PBS,with
R4943 T6002 T6001 arg1Of PBS,ice-cold
R4944 T6003 T5982 modOf and,were
R4945 T6003 T5997 arg2Of and,were
R4946 T6004 T6003 arg2Of incubated,and
R4947 T6004 T6005 arg1Of incubated,for
R4948 T6006 T6005 arg2Of 10 min.,for
R4949 T6006 T6007 arg1Of 10 min.,on
R4950 T6008 T6007 arg2Of ice,on
R4951 T6008 T6009 arg1Of ice,after
R4952 T6010 T6009 arg2Of resuspension,after
R4953 T6010 T6011 arg1Of resuspension,in
R4954 T6014 T6011 arg2Of buffer,in
R4955 T6014 T6012 arg1Of buffer,SDS
R4956 T6014 T6013 arg1Of buffer,lysis
R4957 T6014 T6015 arg1Of buffer,(
R4958 T6018 T6015 arg2Of Kit,(
R4959 T6018 T6016 arg1Of Kit,ChIP
R4960 T6018 T6017 arg1Of Kit,Assay
R4961 T6018 T6019 arg1Of Kit,","
R4962 T6020 T6019 arg2Of Upstate,","
R4963 T6021 T6015 arg3Of ),(
R4964 T6023 T6022 arg2Of centrifugation,After
R4965 T6025 T6026 arg1Of pellets,were
R4966 T6025 T6027 arg2Of pellets,resuspended
R4967 T6027 T6022 arg1Of resuspended,After
R4968 T6027 T6024 arg1Of resuspended,","
R4969 T6027 T6026 arg2Of resuspended,were
R4970 T6027 T6028 arg1Of resuspended,in
R4971 T6031 T6028 arg2Of buffer,in
R4972 T6031 T6029 arg1Of buffer,MNase
R4973 T6031 T6030 arg1Of buffer,reaction
R4974 T6031 T6032 arg1Of buffer,(
R4975 T6035 T6033 arg1Of pH,10 mM
R4976 T6035 T6034 arg1Of pH,Tris-HCl
R4977 T6035 T6036 arg1Of pH,7.5
R4978 T6035 T6037 arg1Of pH,","
R4979 T6037 T6040 arg1Of ",",","
R4980 T6039 T6037 arg2Of NaCl,","
R4981 T6039 T6038 arg1Of NaCl,10 mM
R4982 T6040 T6043 arg1Of ",",","
R4983 T6042 T6040 arg2Of MgCl2,","
R4984 T6042 T6041 arg1Of MgCl2,3 mM
R4985 T6043 T6046 arg1Of ",",","
R4986 T6045 T6043 arg2Of CaCl2,","
R4987 T6045 T6044 arg1Of CaCl2,1 mM
R4988 T6046 T6032 arg2Of ",",(
R4989 T6047 T6048 arg1Of 4,%
R4990 T6049 T6046 arg2Of NP-40,","
R4991 T6049 T6047 arg1Of NP-40,4
R4992 T6050 T6032 arg3Of ),(
R4993 T6052 T6051 arg1Of digestion,DNA
R4994 T6052 T6053 arg1Of digestion,was
R4995 T6052 T6054 arg2Of digestion,performed
R4996 T6054 T6053 arg2Of performed,was
R4997 T6055 T6054 arg3Of using,performed
R4998 T6055 T6068 arg1Of using,in
R4999 T6059 T6056 arg1Of Nuclease,50
R50 T86 T84 arg1Of gene,human
R5000 T6059 T6057 arg1Of Nuclease,U
R5001 T6059 T6058 arg1Of Nuclease,Micrococcal
R5002 T6059 T6060 arg1Of Nuclease,(
R5003 T6059 T6063 arg1Of Nuclease,and
R5004 T6061 T6060 arg2Of Fermentas,(
R5005 T6062 T6060 arg3Of ),(
R5006 T6063 T6055 arg2Of and,using
R5007 T6065 T6063 arg2Of cells,and
R5008 T6065 T6064 arg1Of cells,1 × 107
R5009 T6065 T6066 arg1Of cells,per
R5010 T6067 T6066 arg2Of tube,per
R5011 T6070 T6068 arg2Of volume,in
R5012 T6070 T6069 arg1Of volume,a
R5013 T6070 T6071 arg1Of volume,of
R5014 T6072 T6071 arg2Of 1.5 ml,of
R5015 T6074 T6073 arg2Of 2 min,After
R5016 T6076 T6077 arg1Of reaction,was
R5017 T6076 T6078 arg2Of reaction,stopped
R5018 T6078 T6073 arg1Of stopped,After
R5019 T6078 T6075 arg1Of stopped,","
R5020 T6078 T6077 arg2Of stopped,was
R5021 T6078 T6079 arg1Of stopped,by
R5022 T6080 T6079 arg2Of adding,by
R5023 T6083 T6080 arg2Of EGTA,adding
R5024 T6083 T6081 arg1Of EGTA,30 µl
R5025 T6083 T6082 arg1Of EGTA,200 mM
R5026 T6085 T6084 arg1Of steps,Further
R5027 T6085 T6086 arg1Of steps,were
R5028 T6085 T6087 arg2Of steps,performed
R5029 T6087 T6086 arg2Of performed,were
R5030 T6088 T6087 arg3Of using,performed
R5031 T6088 T6097 arg1Of using,according
R5032 T6092 T6090 arg1Of Assay,Chromatin
R5033 T6092 T6091 arg1Of Assay,Immunoprecipitation
R5034 T6093 T6088 arg2Of Kit,using
R5035 T6093 T6089 arg1Of Kit,the
R5036 T6093 T6092 arg1Of Kit,Assay
R5037 T6093 T6094 arg1Of Kit,(
R5038 T6095 T6094 arg2Of Upstate,(
R5039 T6096 T6094 arg3Of ),(
R5040 T6098 T6097 arg2Of to,according
R5041 T6100 T6099 arg1Of manufacturer,the
R5042 T6100 T6101 arg2Of manufacturer,'s
R5043 T6102 T6098 arg2Of instructions,to
R5044 T6102 T6101 arg1Of instructions,'s
R5045 T6104 T6103 arg1Of cells,1 × 107
R5046 T6104 T6105 arg1Of cells,and
R5047 T6105 T6131 arg1Of and,were
R5048 T6105 T6132 arg2Of and,used
R5049 T6107 T6105 arg2Of antibody,and
R5050 T6107 T6106 arg1Of antibody,2 µg
R5051 T6107 T6108 arg1Of antibody,(
R5052 T6111 T6110 arg2Of Pep2,(
R5053 T6112 T6110 arg3Of ),(
R5054 T6113 T6109 arg1Of sc-59,Sp1
R5055 T6113 T6110 arg1Of sc-59,(
R5056 T6113 T6114 arg1Of sc-59,","
R5057 T6114 T6120 arg1Of ",",or
R5058 T6117 T6116 arg2Of D-20,(
R5059 T6118 T6116 arg3Of ),(
R5060 T6119 T6114 arg2Of sc-644,","
R5061 T6119 T6115 arg1Of sc-644,Sp3
R5062 T6119 T6116 arg1Of sc-644,(
R5063 T6120 T6108 arg2Of or,(
R5064 T6123 T6122 arg2Of H-196,(
R5065 T6124 T6122 arg3Of ),(
R5066 T6125 T6120 arg2Of sc-7210,or
R5067 T6125 T6121 arg1Of sc-7210,actin
R5068 T6125 T6122 arg1Of sc-7210,(
R5069 T6125 T6126 arg1Of sc-7210,","
R5070 T6129 T6126 arg2Of Biotechnology,","
R5071 T6129 T6127 arg1Of Biotechnology,Santa
R5072 T6129 T6128 arg1Of Biotechnology,Cruz
R5073 T6130 T6108 arg3Of ),(
R5074 T6132 T6131 arg2Of used,were
R5075 T6132 T6133 arg1Of used,for
R5076 T6135 T6133 arg2Of immunoprecipitation,for
R5077 T6135 T6134 arg1Of immunoprecipitation,each
R5078 T6137 T6136 arg1Of buffers,All
R5079 T6137 T6138 arg1Of buffers,were
R5080 T6137 T6140 arg2Of buffers,supplied
R5081 T6140 T6138 arg2Of supplied,were
R5082 T6140 T6139 arg1Of supplied,freshly
R5083 T6140 T6141 arg1Of supplied,with
R5084 T6143 T6141 arg2Of inhibitors,with
R5085 T6143 T6142 arg1Of inhibitors,protease
R5086 T6146 T6145 arg1Of extraction,phenol/chloroform
R5087 T6146 T6147 arg1Of extraction,and
R5088 T6147 T6144 arg2Of and,After
R5089 T6149 T6147 arg2Of precipitation,and
R5090 T6149 T6148 arg1Of precipitation,ethanol
R5091 T6151 T6152 arg1Of DNA,was
R5092 T6151 T6153 arg2Of DNA,resolved
R5093 T6153 T6144 arg1Of resolved,After
R5094 T6153 T6150 arg1Of resolved,","
R5095 T6153 T6152 arg2Of resolved,was
R5096 T6153 T6154 arg1Of resolved,in
R5097 T6156 T6154 arg2Of H2O,in
R5098 T6156 T6155 arg1Of H2O,16 µl
R5099 T6158 T6157 arg2Of DNA,Immunoprecipitated
R51 T86 T85 arg1Of gene,APOBEC3G
R5100 T6158 T6159 arg1Of DNA,was
R5101 T6158 T6160 arg2Of DNA,detected
R5102 T6158 T6164 arg1Of DNA,using
R5103 T6160 T6159 arg2Of detected,was
R5104 T6160 T6164 modOf detected,using
R5105 T6163 T6160 arg1Of PCR,detected
R5106 T6163 T6161 arg2Of PCR,by
R5107 T6163 T6162 arg2Of PCR,nested
R5108 T6165 T6164 arg2Of 4 µl,using
R5109 T6165 T6166 arg1Of 4 µl,of
R5110 T6169 T6168 arg2Of DNA,resolved
R5111 T6169 T6170 arg1Of DNA,in
R5112 T6169 T6175 arg1Of DNA,and
R5113 T6173 T6170 arg2Of PCR,in
R5114 T6173 T6171 arg1Of PCR,the
R5115 T6173 T6172 arg1Of PCR,first
R5116 T6175 T6166 arg2Of and,of
R5117 T6175 T6167 arg1Of and,the
R5118 T6175 T6174 arg1Of and,","
R5119 T6176 T6175 arg2Of 1 µl,and
R5120 T6176 T6177 arg1Of 1 µl,for
R5121 T6180 T6177 arg2Of PCR,for
R5122 T6180 T6178 arg1Of PCR,the
R5123 T6180 T6179 arg1Of PCR,nested
R5124 T6182 T6181 arg2Of amplification,For
R5125 T6182 T6183 arg1Of amplification,of
R5126 T6186 T6183 arg2Of promoter,of
R5127 T6186 T6184 arg1Of promoter,the
R5128 T6186 T6185 arg1Of promoter,A3G
R5129 T6190 T6188 arg1Of primers,the
R5130 T6190 T6189 arg1Of primers,following
R5131 T6190 T6191 arg1Of primers,were
R5132 T6190 T6192 arg2Of primers,used
R5133 T6192 T6181 arg1Of used,For
R5134 T6192 T6187 arg1Of used,","
R5135 T6192 T6191 arg2Of used,were
R5136 T6192 T6193 arg1Of used,:
R5137 T6194 T6195 arg1Of ChIP3Gplus,5′-ccacggtggcctccgagggtga-3′
R5138 T6194 T6196 arg1Of ChIP3Gplus,and
R5139 T6197 T6196 arg2Of ChIP3Gminus,and
R5140 T6197 T6198 arg1Of ChIP3Gminus,:
R5141 T6199 T6200 arg1Of 5′-ctctccaccatcaagacagac-3′,(
R5142 T6199 T6201 arg1Of 5′-ctctccaccatcaagacagac-3′,1
R5143 T6202 T6203 arg1Of PCR,)
R5144 T6202 T6204 arg1Of PCR,;
R5145 T6205 T6204 arg2Of ChIP3G2plus,;
R5146 T6205 T6206 arg1Of ChIP3G2plus,:
R5147 T6207 T6208 arg1Of 5′-tactctccctccctgtcccca-3′,and
R5148 T6208 T6212 arg1Of and,:
R5149 T6210 T6209 arg1Of nested,ChIP3G
R5150 T6211 T6208 arg2Of minus,and
R5151 T6211 T6210 arg1Of minus,nested
R5152 T6213 T6214 arg1Of 5′-aggctgatgcctccgcag-3′,(
R5153 T6215 T6214 arg2Of nested,(
R5154 T6216 T6215 arg3Of PCR,nested
R5155 T6217 T6214 arg3Of ),(
R5156 T6219 T6218 arg1Of polymerase,Taq
R5157 T6219 T6220 arg1Of polymerase,(
R5158 T6219 T6223 arg1Of polymerase,was
R5159 T6219 T6224 arg2Of polymerase,used
R5160 T6221 T6220 arg2Of Qiagen,(
R5161 T6222 T6220 arg3Of ),(
R5162 T6224 T6223 arg2Of used,was
R5163 T6224 T6225 arg1Of used,together
R5164 T6224 T6226 arg1Of used,with
R5165 T6230 T6226 arg2Of conditions,with
R5166 T6230 T6227 arg1Of conditions,the
R5167 T6230 T6228 arg1Of conditions,following
R5168 T6230 T6229 arg1Of conditions,cycle
R5169 T6230 T6231 arg1Of conditions,:
R5170 T6234 T6231 arg2Of 94°C,:
R5171 T6234 T6232 arg1Of 94°C,one
R5172 T6234 T6233 arg1Of 94°C,cycle
R5173 T6234 T6235 arg1Of 94°C,for
R5174 T6234 T6237 arg1Of 94°C,;
R5175 T6236 T6235 arg2Of 2 min,for
R5176 T6239 T6238 arg1Of cycles,30
R5177 T6240 T6241 arg1Of 94°C,for
R5178 T6240 T6249 arg1Of 94°C,for
R5179 T6240 T6251 arg1Of 94°C,;
R5180 T6242 T6241 arg2Of 30 s,for
R5181 T6242 T6243 arg1Of 30 s,","
R5182 T6242 T6247 arg1Of 30 s,","
R5183 T6244 T6243 arg2Of 60°C,","
R5184 T6244 T6245 arg1Of 60°C,for
R5185 T6246 T6245 arg2Of 60 s,for
R5186 T6248 T6247 arg2Of 72°C,","
R5187 T6250 T6249 arg2Of 2 min,for
R5188 T6251 T6237 arg2Of ;,;
R5189 T6251 T6239 arg1Of ;,cycles
R5190 T6254 T6251 arg2Of 72°C,;
R5191 T6254 T6252 arg1Of 72°C,one
R5192 T6254 T6253 arg1Of 72°C,cycle
R5193 T6254 T6255 arg1Of 72°C,for
R5194 T6256 T6255 arg2Of 10 min,for
R5195 T6260 T6257 arg2Of control,As
R5196 T6260 T6258 arg1Of control,a
R5197 T6260 T6259 arg1Of control,negative
R5198 T6263 T6262 arg1Of region,a
R5199 T6263 T6264 arg1Of region,in
R52 T87 T88 arg1Of APOBEC3G,(
R5200 T6263 T6268 arg1Of region,was
R5201 T6263 T6269 arg2Of region,targeted
R5202 T6267 T6264 arg2Of gene,in
R5203 T6267 T6265 arg1Of gene,the
R5204 T6267 T6266 arg1Of gene,A3G
R5205 T6269 T6257 arg1Of targeted,As
R5206 T6269 T6261 arg1Of targeted,","
R5207 T6269 T6268 arg2Of targeted,was
R5208 T6269 T6270 modOf targeted,using
R5209 T6269 T6274 arg1Of targeted,:
R5210 T6273 T6270 arg2Of ChIP3Gneg_plus,using
R5211 T6273 T6271 arg1Of ChIP3Gneg_plus,the
R5212 T6273 T6272 arg1Of ChIP3Gneg_plus,primers
R5213 T6275 T6276 arg1Of 5′-taagtaccacccagagatgag-3′,and
R5214 T6276 T6278 arg1Of and,:
R5215 T6277 T6276 arg2Of ChIP3Gneg_minus,and
R5216 T6279 T6280 arg1Of 5′-catgatcttcatggtggcacg-3′,for
R5217 T6283 T6280 arg2Of steps,for
R5218 T6283 T6281 arg1Of steps,both
R5219 T6283 T6282 arg1Of steps,PCR
R5220 T6285 T6284 arg1Of conditions,PCR
R5221 T6285 T6286 arg1Of conditions,were
R5222 T6286 T6295 arg1Of were,","
R5223 T6286 T6296 arg1Of were,with
R5224 T6288 T6286 arg2Of same,were
R5225 T6288 T6287 arg1Of same,the
R5226 T6288 T6289 arg1Of same,as
R5227 T6289 T6290 arg1Of as,for
R5228 T6294 T6290 arg2Of sequence,for
R5229 T6294 T6291 arg1Of sequence,the
R5230 T6294 T6292 arg1Of sequence,A3G
R5231 T6294 T6293 arg1Of sequence,promoter
R5232 T6298 T6296 arg2Of exception,with
R5233 T6298 T6297 arg1Of exception,the
R5234 T6298 T6299 arg1Of exception,that
R5235 T6301 T6300 arg1Of temperature,annealing
R5236 T6301 T6302 arg1Of temperature,was
R5237 T6301 T6303 arg2Of temperature,decreased
R5238 T6303 T6299 arg2Of decreased,that
R5239 T6303 T6302 arg2Of decreased,was
R5240 T6303 T6304 arg1Of decreased,to
R5241 T6305 T6304 arg2Of 55°C,to
R53 T87 T91 arg1Of APOBEC3G,","
R54 T87 T104 arg1Of APOBEC3G,is
R55 T87 T105 arg2Of APOBEC3G,expressed
R56 T87 T111 arg1Of APOBEC3G,has
R5660 T6869 T6864 arg1Of analysis,RNA
R5661 T6869 T6865 arg1Of analysis,interference
R5662 T6869 T6866 arg1Of analysis,and
R5663 T6869 T6867 arg1Of analysis,western
R5664 T6869 T6868 arg1Of analysis,blot
R5665 T6870 T6871 arg1Of Sp1,and
R5666 T6872 T6871 arg2Of Sp3,and
R5667 T6873 T6870 arg1Of translation,Sp1
R5668 T6873 T6872 arg1Of translation,Sp3
R5669 T6873 T6874 arg1Of translation,was
R5670 T6873 T6875 arg2Of translation,silenced
R5671 T6875 T6874 arg2Of silenced,was
R5672 T6875 T6876 arg1Of silenced,in
R5673 T6878 T6876 arg2Of cells,in
R5674 T6878 T6877 arg1Of cells,HeLa
R5675 T6879 T6875 arg3Of using,silenced
R5676 T6882 T6880 arg1Of duplexes,the
R5677 T6882 T6881 arg1Of duplexes,siRNA
R5678 T6883 T6882 arg1Of Hs_SP1_1_HP,duplexes
R5679 T6883 T6884 arg1Of Hs_SP1_1_HP,and
R5680 T6884 T6879 arg2Of and,using
R5681 T6885 T6884 arg2Of Hs_SP3_1_HP,and
R5682 T6885 T6886 arg1Of Hs_SP3_1_HP,(
R5683 T6887 T6886 arg2Of Qiagen,(
R5684 T6888 T6886 arg3Of ),(
R5685 T6891 T6889 arg1Of siRNA,A
R5686 T6891 T6890 arg1Of siRNA,nonspecific
R5687 T6891 T6892 arg1Of siRNA,(
R5688 T6891 T6895 arg1Of siRNA,was
R5689 T6891 T6896 arg2Of siRNA,used
R5690 T6893 T6892 arg2Of Qiagen,(
R5691 T6894 T6892 arg3Of ),(
R5692 T6896 T6895 arg2Of used,was
R5693 T6896 T6897 arg1Of used,as
R5694 T6898 T6897 arg2Of control,as
R5695 T6900 T6899 arg1Of cells,HeLa
R5696 T6900 T6901 arg1Of cells,were
R5697 T6900 T6902 arg2Of cells,transfected
R5698 T6902 T6901 arg2Of transfected,were
R5699 T6902 T6903 arg1Of transfected,with
R57 T87 T112 arg1Of APOBEC3G,been
R5700 T6904 T6905 arg1Of 150,or
R5701 T6906 T6905 arg2Of 300 ng,or
R5702 T6907 T6903 arg2Of siRNA,with
R5703 T6907 T6904 arg1Of siRNA,150
R5704 T6907 T6906 arg1Of siRNA,300 ng
R5705 T6907 T6908 arg1Of siRNA,per
R5706 T6907 T6910 arg1Of siRNA,","
R5707 T6909 T6908 arg2Of 6-well,per
R5708 T6911 T6910 arg2Of using,","
R5709 T6911 T6919 arg1Of using,according
R5710 T6911 T6925 arg1Of using,for
R5711 T6915 T6911 arg2Of reagent,using
R5712 T6915 T6912 arg1Of reagent,the
R5713 T6915 T6913 arg1Of reagent,HiPerfect
R5714 T6915 T6914 arg1Of reagent,transfection
R5715 T6915 T6916 arg1Of reagent,(
R5716 T6917 T6916 arg2Of Qiagen,(
R5717 T6918 T6916 arg3Of ),(
R5718 T6920 T6919 arg2Of to,according
R5719 T6922 T6921 arg1Of manufacturer,the
R5720 T6922 T6923 arg2Of manufacturer,'s
R5721 T6924 T6920 arg2Of protocol,to
R5722 T6924 T6923 arg1Of protocol,'s
R5723 T6927 T6925 arg2Of transfection,for
R5724 T6927 T6926 arg1Of transfection,reverse
R5725 T6927 T6928 arg1Of transfection,of
R5726 T6930 T6928 arg2Of cells,of
R5727 T6930 T6929 arg1Of cells,adherent
R5728 T6930 T6931 arg1Of cells,in
R5729 T6933 T6931 arg2Of plates,in
R5730 T6933 T6932 arg1Of plates,6-well
R5731 T6935 T6934 arg1Of hours,Forty-eight
R5732 T6936 T6935 arg1Of after,hours
R5733 T6937 T6936 arg2Of transfection,after
R5734 T6940 T6939 arg1Of cells,HeLa
R5735 T6940 T6941 arg1Of cells,were
R5736 T6940 T6942 arg2Of cells,harvested
R5737 T6942 T6936 arg1Of harvested,after
R5738 T6942 T6938 arg1Of harvested,","
R5739 T6942 T6941 arg2Of harvested,were
R5740 T6942 T6943 arg1Of harvested,for
R5741 T6944 T6943 arg2Of detection,for
R5742 T6944 T6945 arg1Of detection,of
R5743 T6946 T6947 arg1Of Sp1,and
R5744 T6948 T6947 arg2Of Sp3,and
R5745 T6949 T6945 arg2Of proteins,of
R5746 T6949 T6946 arg1Of proteins,Sp1
R5747 T6949 T6948 arg1Of proteins,Sp3
R5748 T6950 T6951 arg1Of Cells,were
R5749 T6950 T6952 arg2Of Cells,washed
R5750 T6952 T6951 arg2Of washed,were
R5751 T6952 T6953 arg1Of washed,in
R5752 T6952 T6993 arg1Of washed,and
R5753 T6954 T6953 arg2Of PBS,in
R5754 T6954 T6955 arg1Of PBS,","
R5755 T6954 T6956 arg2Of PBS,lysed
R5756 T6954 T6959 arg1Of PBS,(
R5757 T6956 T6957 arg1Of lysed,in
R5758 T6958 T6957 arg2Of RIPA,in
R5759 T6962 T6960 arg1Of pH,25 mM
R5760 T6962 T6961 arg1Of pH,Tris
R5761 T6962 T6963 arg1Of pH,8.0
R5762 T6962 T6964 arg1Of pH,","
R5763 T6964 T6967 arg1Of ",",","
R5764 T6966 T6964 arg2Of NaCl,","
R5765 T6966 T6965 arg1Of NaCl,137 mM
R5766 T6967 T6971 arg1Of ",",","
R5767 T6968 T6969 arg1Of 1,%
R5768 T6970 T6967 arg2Of Glycerol,","
R5769 T6970 T6968 arg1Of Glycerol,1
R5770 T6971 T6976 arg1Of ",",","
R5771 T6972 T6973 arg1Of 0.5,%
R5772 T6975 T6971 arg2Of deoxycholate,","
R5773 T6975 T6972 arg1Of deoxycholate,0.5
R5774 T6975 T6974 arg1Of deoxycholate,sodium
R5775 T6976 T6980 arg1Of ",",","
R5776 T6977 T6978 arg1Of 1,%
R5777 T6979 T6976 arg2Of NP-40,","
R5778 T6979 T6977 arg1Of NP-40,1
R5779 T6980 T6985 arg1Of ",",","
R5780 T6983 T6980 arg2Of pH,","
R5781 T6983 T6981 arg1Of pH,2 mM
R5782 T6983 T6982 arg1Of pH,EDTA
R5783 T6983 T6984 arg1Of pH,8
R5784 T6985 T6959 arg2Of ",",(
R5785 T6986 T6987 arg1Of 0.1,%
R5786 T6988 T6986 arg1Of SDS,0.1
R5787 T6988 T6989 arg1Of SDS,and
R5788 T6989 T6985 arg2Of and,","
R5789 T6991 T6989 arg2Of inhibitors,and
R5790 T6991 T6990 arg1Of inhibitors,protease
R5791 T6992 T6959 arg3Of ),(
R5792 T6994 T6995 arg1Of lysates,were
R5793 T6994 T6996 arg2Of lysates,cleared
R5794 T6996 T6993 arg2Of cleared,and
R5795 T6996 T6995 arg2Of cleared,were
R5796 T6998 T6996 arg1Of centrifugation,cleared
R5797 T6998 T6997 arg2Of centrifugation,by
R5798 T7000 T6999 arg2Of boiling,After
R5799 T7000 T7001 arg1Of boiling,with
R58 T87 T113 arg2Of APOBEC3G,shown
R5800 T7003 T7001 arg2Of buffer,with
R5801 T7003 T7002 arg1Of buffer,Laemmli′s
R5802 T7005 T7000 arg1Of samples,boiling
R5803 T7005 T7006 arg1Of samples,were
R5804 T7005 T7007 arg2Of samples,subjected
R5805 T7007 T6999 arg1Of subjected,After
R5806 T7007 T7004 arg1Of subjected,","
R5807 T7007 T7006 arg2Of subjected,were
R5808 T7007 T7008 arg1Of subjected,to
R5809 T7007 T7012 modOf subjected,followed
R5810 T7011 T7008 arg2Of electrophoresis,to
R5811 T7011 T7009 arg1Of electrophoresis,SDS–polyacrylamide
R5812 T7011 T7010 arg1Of electrophoresis,gel
R5813 T7014 T7012 arg1Of transfer,followed
R5814 T7014 T7013 arg2Of transfer,by
R5815 T7014 T7015 arg1Of transfer,to
R5816 T7018 T7015 arg2Of membrane,to
R5817 T7018 T7016 arg1Of membrane,a
R5818 T7018 T7017 arg1Of membrane,nitrocellulose
R5819 T7019 T7020 arg1Of Sp1,and
R5820 T7021 T7020 arg2Of Sp3,and
R5821 T7022 T7019 arg1Of proteins,Sp1
R5822 T7022 T7021 arg1Of proteins,Sp3
R5823 T7022 T7023 arg1Of proteins,were
R5824 T7022 T7024 arg2Of proteins,detected
R5825 T7024 T7023 arg2Of detected,were
R5826 T7025 T7024 arg3Of using,detected
R5827 T7025 T7049 modOf using,followed
R5828 T7028 T7027 arg2Of Pep2,(
R5829 T7029 T7027 arg3Of ),(
R5830 T7030 T7026 arg1Of antibody,α-Sp1
R5831 T7030 T7027 arg1Of antibody,(
R5832 T7030 T7031 arg1Of antibody,(
R5833 T7030 T7037 arg1Of antibody,or
R5834 T7032 T7031 arg2Of sc-59,(
R5835 T7032 T7033 arg1Of sc-59,","
R5836 T7035 T7033 arg2Of Cruz,","
R5837 T7035 T7034 arg1Of Cruz,Santa
R5838 T7036 T7031 arg3Of ),(
R5839 T7037 T7025 arg2Of or,using
R5840 T7037 T7043 arg1Of or,(
R5841 T7040 T7039 arg2Of D-20,(
R5842 T7041 T7039 arg3Of ),(
R5843 T7042 T7037 arg2Of antibody,or
R5844 T7042 T7038 arg1Of antibody,α-Sp3
R5845 T7042 T7039 arg1Of antibody,(
R5846 T7044 T7043 arg2Of sc-644,(
R5847 T7044 T7045 arg1Of sc-644,","
R5848 T7047 T7045 arg2Of Cruz,","
R5849 T7047 T7046 arg1Of Cruz,Santa
R5850 T7048 T7043 arg3Of ),(
R5851 T7051 T7049 arg1Of incubation,followed
R5852 T7051 T7050 arg2Of incubation,by
R5853 T7051 T7052 arg1Of incubation,with
R5854 T7053 T7052 arg2Of α-rabbit-HRP,with
R5855 T7053 T7054 arg1Of α-rabbit-HRP,(
R5856 T7056 T7054 arg2Of Biosciences,(
R5857 T7056 T7055 arg1Of Biosciences,Amersham
R5858 T7057 T7054 arg3Of ),(
R5859 T7059 T7058 arg2Of detection,For
R5860 T7059 T7060 arg1Of detection,of
R5861 T7061 T7060 arg2Of tubulin,of
R5862 T7063 T7064 arg1Of α-tubulin,(
R5863 T7063 T7069 arg1Of α-tubulin,and
R5864 T7065 T7064 arg2Of B5-1-2,(
R5865 T7065 T7066 arg1Of B5-1-2,","
R5866 T7067 T7066 arg2Of Sigma,","
R5867 T7068 T7064 arg3Of ),(
R5868 T7069 T7076 arg1Of and,were
R5869 T7069 T7077 arg2Of and,used
R5870 T7073 T7071 arg2Of Biosciences,(
R5871 T7073 T7072 arg1Of Biosciences,Amersham
R5872 T7074 T7071 arg3Of ),(
R5873 T7075 T7069 arg2Of antibodies,and
R5874 T7075 T7070 arg1Of antibodies,α-mouse-HRP
R5875 T7075 T7071 arg1Of antibodies,(
R5876 T7077 T7058 arg1Of used,For
R5877 T7077 T7062 arg1Of used,","
R5878 T7077 T7076 arg2Of used,were
R5879 T7078 T7079 arg1Of Signals,were
R5880 T7078 T7080 arg2Of Signals,visualized
R5881 T7080 T7079 arg2Of visualized,were
R5882 T7083 T7080 arg1Of chemiluminescence,visualized
R5883 T7083 T7081 arg2Of chemiluminescence,by
R5884 T7083 T7082 arg2Of chemiluminescence,enhanced
R5885 T7083 T7084 arg1Of chemiluminescence,(
R5886 T7085 T7084 arg2Of ECL,(
R5887 T7085 T7086 arg1Of ECL,","
R5888 T7088 T7086 arg2Of Biosciences,","
R5889 T7088 T7087 arg1Of Biosciences,Amersham
R5890 T7089 T7084 arg3Of ),(
R59 T87 T115 arg1Of APOBEC3G,be
R60 T87 T116 arg1Of APOBEC3G,active
R61 T89 T88 arg2Of A3G,(
R6162 T7499 T7500 arg1Of Characterization,of
R6163 T7499 T7507 arg1Of Characterization,by
R6164 T7504 T7500 arg2Of sites,of
R6165 T7504 T7501 arg1Of sites,the
R6166 T7504 T7502 arg1Of sites,transcriptional
R6167 T7504 T7503 arg1Of sites,start
R6168 T7504 T7505 arg1Of sites,of
R6169 T7506 T7505 arg2Of APOBEC3G,of
R6170 T7508 T7507 arg2Of 5′-RACE,by
R6171 T7510 T7509 arg1Of identify,To
R6172 T7514 T7510 arg2Of sites,identify
R6173 T7514 T7511 arg1Of sites,the
R6174 T7514 T7512 arg1Of sites,transcriptional
R6175 T7514 T7513 arg1Of sites,start
R6176 T7514 T7515 arg1Of sites,(
R6177 T7514 T7518 arg1Of sites,of
R6178 T7516 T7515 arg2Of TSS,(
R6179 T7517 T7515 arg3Of ),(
R6180 T7519 T7518 arg2Of APOBEC3G,of
R6181 T7519 T7520 arg1Of APOBEC3G,(
R6182 T7521 T7520 arg2Of A3G,(
R6183 T7522 T7520 arg3Of ),(
R6184 T7525 T7523 arg2Of cells,in
R6185 T7525 T7524 arg1Of cells,A3.01 T
R6186 T7525 T7528 arg2Of cells,performed
R6187 T7527 T7528 arg1Of we,performed
R6188 T7528 T7526 arg1Of performed,","
R6189 T7530 T7510 arg1Of amplification,identify
R6190 T7530 T7529 arg1Of amplification,5′-rapid
R6191 T7530 T7531 arg1Of amplification,of
R6192 T7530 T7533 arg1Of amplification,ends
R6193 T7532 T7531 arg2Of cDNA,of
R6194 T7533 T7509 modOf ends,To
R6195 T7533 T7523 arg1Of ends,in
R6196 T7533 T7541 arg1Of ends,(
R6197 T7534 T7533 arg2Of analysis,ends
R6198 T7534 T7535 arg1Of analysis,(
R6199 T7534 T7538 arg1Of analysis,with
R62 T90 T88 arg3Of ),(
R6200 T7536 T7535 arg2Of RACE,(
R6201 T7537 T7535 arg3Of ),(
R6202 T7540 T7538 arg2Of primers,with
R6203 T7540 T7539 arg1Of primers,A3G-specific
R6204 T7542 T7541 arg2Of see,(
R6205 T7543 T7542 arg2Of Figure,see
R6206 T7543 T7544 arg1Of Figure,1
R6207 T7545 T7541 arg3Of ),(
R6208 T7548 T7546 arg1Of electrophoresis,Agarose
R6209 T7548 T7547 arg1Of electrophoresis,gel
R6210 T7548 T7549 arg1Of electrophoresis,resolved
R6211 T7549 T7554 arg1Of resolved,into
R6212 T7549 T7561 arg1Of resolved,with
R6213 T7553 T7549 arg2Of products,resolved
R6214 T7553 T7550 arg1Of products,the
R6215 T7553 T7551 arg1Of products,nested
R6216 T7553 T7552 arg1Of products,PCR
R6217 T7556 T7554 arg2Of bands,into
R6218 T7556 T7555 arg1Of bands,three
R6219 T7556 T7557 arg1Of bands,of
R6220 T7560 T7557 arg2Of mobility,of
R6221 T7560 T7558 arg1Of mobility,different
R6222 T7560 T7559 arg1Of mobility,electrophoretic
R6223 T7565 T7561 arg2Of band,with
R6224 T7565 T7562 arg1Of band,a
R6225 T7565 T7563 arg1Of band,dominant
R6226 T7565 T7564 arg1Of band,middle
R6227 T7565 T7566 arg1Of band,(
R6228 T7567 T7566 arg2Of Figure,(
R6229 T7567 T7568 arg1Of Figure,2
R6230 T7569 T7566 arg3Of ),(
R6231 T7572 T7570 arg2Of band,For
R6232 T7572 T7571 arg1Of band,each
R6233 T7575 T7574 arg1Of DNA,the
R6234 T7575 T7576 arg1Of DNA,was
R6235 T7575 T7577 arg2Of DNA,cloned
R6236 T7577 T7576 arg2Of cloned,was
R6237 T7577 T7578 arg1Of cloned,and
R6238 T7578 T7570 arg1Of and,For
R6239 T7578 T7573 arg1Of and,","
R6240 T7580 T7579 arg1Of analysis,sequence
R6241 T7580 T7581 arg1Of analysis,of
R6242 T7580 T7587 arg1Of analysis,was
R6243 T7580 T7588 arg2Of analysis,performed
R6244 T7582 T7583 arg1Of six,or
R6245 T7584 T7583 arg2Of seven,or
R6246 T7586 T7581 arg2Of transformants,of
R6247 T7586 T7582 arg1Of transformants,six
R6248 T7586 T7584 arg1Of transformants,seven
R6249 T7586 T7585 arg1Of transformants,individual
R6250 T7588 T7578 arg2Of performed,and
R6251 T7588 T7587 arg2Of performed,was
R6252 T7589 T7590 arg1Of We,observed
R6253 T7595 T7592 arg1Of sites,the
R6254 T7595 T7593 arg1Of sites,transcriptional
R6255 T7595 T7594 arg1Of sites,start
R6256 T7595 T7596 arg1Of sites,of
R6257 T7595 T7600 arg1Of sites,were
R6258 T7595 T7601 arg1Of sites,located
R6259 T7599 T7596 arg2Of gene,of
R6260 T7599 T7597 arg1Of gene,the
R6261 T7599 T7598 arg1Of gene,A3G
R6262 T7600 T7590 arg2Of were,observed
R6263 T7600 T7591 arg1Of were,that
R6264 T7601 T7600 arg2Of located,were
R6265 T7601 T7602 arg1Of located,between
R6266 T7603 T7604 arg1Of 58,and
R6267 T7604 T7602 arg2Of and,between
R6268 T7604 T7606 arg1Of and,upstream
R6269 T7605 T7604 arg2Of 361 nt,and
R6270 T7606 T7607 arg1Of upstream,of
R6271 T7611 T7607 arg2Of codon,of
R6272 T7611 T7608 arg1Of codon,the
R6273 T7611 T7609 arg1Of codon,ATG
R6274 T7611 T7610 arg1Of codon,start
R6275 T7611 T7612 arg1Of codon,(
R6276 T7613 T7612 arg2Of Figure,(
R6277 T7613 T7614 arg1Of Figure,1
R6278 T7615 T7612 arg3Of ),(
R6279 T7617 T7618 arg1Of TSS,were
R6280 T7617 T7619 arg1Of TSS,variable
R6281 T7618 T7620 arg1Of were,and
R6282 T7619 T7618 arg2Of variable,were
R6283 T7620 T7616 arg2Of and,Although
R6284 T7622 T7621 arg1Of sites,most
R6285 T7622 T7623 arg1Of sites,were
R6286 T7622 T7625 arg2Of sites,detected
R6287 T7625 T7620 arg2Of detected,and
R6288 T7625 T7623 arg2Of detected,were
R6289 T7625 T7624 arg1Of detected,only
R6290 T7625 T7626 arg1Of detected,once
R6291 T7625 T7627 arg1Of detected,among
R6292 T7630 T7627 arg2Of clones,among
R6293 T7630 T7628 arg1Of clones,the
R6294 T7630 T7629 arg1Of clones,19
R6295 T7630 T7631 arg2Of clones,analyzed
R6296 T7634 T7633 arg1Of TSS,one
R6297 T7634 T7635 arg1Of TSS,was
R6298 T7634 T7636 arg2Of TSS,identified
R6299 T7636 T7616 arg1Of identified,Although
R63 T93 T91 arg2Of member,","
R6300 T7636 T7632 arg1Of identified,","
R6301 T7636 T7635 arg2Of identified,was
R6302 T7636 T7637 arg1Of identified,in
R6303 T7640 T7637 arg2Of clones,in
R6304 T7640 T7638 arg1Of clones,six
R6305 T7640 T7639 arg1Of clones,individual
R6306 T7642 T7641 arg1Of TSS,This
R6307 T7642 T7643 arg1Of TSS,was
R6308 T7642 T7644 arg2Of TSS,located
R6309 T7644 T7643 arg2Of located,was
R6310 T7644 T7646 arg1Of located,upstream
R6311 T7644 T7662 arg1Of located,and
R6312 T7646 T7645 arg1Of upstream,66 nt
R6313 T7646 T7647 arg1Of upstream,of
R6314 T7649 T7647 arg2Of start,of
R6315 T7649 T7648 arg1Of start,the
R6316 T7649 T7650 arg1Of start,of
R6317 T7655 T7650 arg2Of sequence,of
R6318 T7655 T7651 arg1Of sequence,the
R6319 T7655 T7652 arg2Of sequence,published
R6320 T7655 T7653 arg1Of sequence,A3G
R6321 T7655 T7654 arg1Of sequence,mRNA
R6322 T7655 T7656 arg1Of sequence,(
R6323 T7660 T7656 arg2Of NM021822,(
R6324 T7660 T7657 arg1Of NM021822,GenBank™
R6325 T7660 T7658 arg1Of NM021822,accession
R6326 T7660 T7659 arg1Of NM021822,number
R6327 T7661 T7656 arg3Of ),(
R6328 T7663 T7664 arg1Of we,defined
R6329 T7664 T7662 arg2Of defined,and
R6330 T7666 T7664 arg2Of position,defined
R6331 T7666 T7665 arg1Of position,this
R6332 T7666 T7667 arg1Of position,as
R6333 T7672 T7667 arg2Of site,as
R6334 T7672 T7668 arg1Of site,the
R6335 T7672 T7669 arg1Of site,major
R6336 T7672 T7670 arg1Of site,transcriptional
R6337 T7672 T7671 arg1Of site,start
R6338 T7672 T7673 arg1Of site,of
R6339 T7676 T7673 arg2Of gene,of
R6340 T7676 T7674 arg1Of gene,the
R6341 T7676 T7675 arg1Of gene,A3G
R64 T93 T92 arg1Of member,a
R65 T93 T94 arg1Of member,of
R6555 T7995 T7993 arg1Of promoter,The
R6556 T7995 T7994 arg1Of promoter,core
R6557 T7995 T7996 arg1Of promoter,of
R6558 T7995 T7998 arg1Of promoter,is
R6559 T7995 T7999 arg1Of promoter,located
R6560 T7997 T7996 arg2Of A3G,of
R6561 T7999 T7998 arg2Of located,is
R6562 T7999 T8000 arg1Of located,within
R6563 T8002 T8000 arg2Of region,within
R6564 T8002 T8001 arg1Of region,the
R6565 T8002 T8003 arg1Of region,−114/+66
R6566 T8002 T8005 arg1Of region,to
R6567 T8005 T8004 arg1Of to,relative
R6568 T8007 T8005 arg2Of TSS,to
R6569 T8007 T8006 arg1Of TSS,the
R6570 T8009 T8008 arg2Of characterization,For
R6571 T8009 T8010 arg1Of characterization,of
R6572 T8013 T8010 arg2Of promoter,of
R6573 T8013 T8011 arg1Of promoter,the
R6574 T8013 T8012 arg1Of promoter,A3G
R6575 T8015 T8016 arg1Of we,cloned
R6576 T8015 T8037 arg2Of we,designated
R6577 T8016 T8036 arg1Of cloned,and
R6578 T8018 T8016 arg2Of 1025 bp,cloned
R6579 T8018 T8017 arg1Of 1025 bp,the
R658 T883 T882 arg1Of discovered,recently
R6580 T8018 T8019 arg1Of 1025 bp,located
R6581 T8019 T8020 arg1Of located,at
R6582 T8021 T8020 arg2Of position,at
R6583 T8021 T8022 arg1Of position,−959/+66
R6584 T8021 T8024 arg1Of position,to
R6585 T8024 T8023 arg1Of to,relative
R6586 T8028 T8024 arg2Of start,to
R6587 T8028 T8025 arg1Of start,the
R6588 T8028 T8026 arg2Of start,identified
R6589 T8028 T8027 arg1Of start,transcription
R659 T885 T881 arg1Of family,The
R6590 T8028 T8029 arg1Of start,into
R6591 T8035 T8029 arg2Of plasmid,into
R6592 T8035 T8030 arg1Of plasmid,the
R6593 T8035 T8031 arg1Of plasmid,promoterless
R6594 T8035 T8032 arg1Of plasmid,pGL3-Basic
R6595 T8035 T8033 arg1Of plasmid,luciferase
R6596 T8035 T8034 arg1Of plasmid,reporter
R6597 T8036 T8008 arg1Of and,For
R6598 T8036 T8014 arg1Of and,","
R6599 T8037 T8036 arg2Of designated,and
R66 T97 T96 arg1Of discovered,recently
R660 T885 T883 arg1Of family,discovered
R6600 T8040 T8037 arg3Of pGL3-Basic-APOprom1025,designated
R6601 T8040 T8038 arg1Of pGL3-Basic-APOprom1025,the
R6602 T8040 T8039 arg1Of pGL3-Basic-APOprom1025,plasmid
R6603 T8043 T8044 arg1Of pGL3-APOprom502,(
R6604 T8043 T8049 arg1Of pGL3-APOprom502,","
R6605 T8045 T8044 arg2Of containing,(
R6606 T8046 T8045 arg2Of sequence,containing
R6607 T8046 T8047 arg1Of sequence,−436/+66
R6608 T8048 T8044 arg3Of ),(
R6609 T8049 T8056 arg1Of ",",and
R661 T885 T884 arg1Of family,APOBEC3
R6610 T8050 T8049 arg2Of pGL3-APOprom225,","
R6611 T8050 T8051 arg1Of pGL3-APOprom225,(
R6612 T8052 T8051 arg2Of containing,(
R6613 T8053 T8052 arg2Of sequence,containing
R6614 T8053 T8054 arg1Of sequence,−159/+66
R6615 T8055 T8051 arg3Of ),(
R6616 T8056 T8074 arg1Of and,were
R6617 T8056 T8075 arg2Of and,generated
R6618 T8061 T8056 arg2Of constructs,and
R6619 T8061 T8057 arg1Of constructs,further
R662 T885 T886 arg1Of family,of
R6620 T8061 T8058 arg1Of constructs,5′
R6621 T8061 T8059 arg1Of constructs,deletion
R6622 T8061 T8060 arg1Of constructs,reporter
R6623 T8061 T8062 arg1Of constructs,containing
R6624 T8063 T8064 arg1Of 180,","
R6625 T8064 T8062 arg2Of ",",containing
R6626 T8064 T8066 arg1Of ",",","
R6627 T8065 T8064 arg2Of 150,","
R6628 T8067 T8068 arg1Of 120,or
R6629 T8068 T8066 arg2Of or,","
R663 T885 T889 arg1Of family,is
R6630 T8068 T8070 arg1Of or,upstream
R6631 T8069 T8068 arg2Of 60 bp,or
R6632 T8070 T8071 arg1Of upstream,of
R6633 T8072 T8071 arg2Of position,of
R6634 T8072 T8073 arg1Of position,+65
R6635 T8075 T8041 arg1Of generated,Similarly
R6636 T8075 T8042 arg1Of generated,","
R6637 T8075 T8074 arg2Of generated,were
R6638 T8075 T8076 arg1Of generated,(
R6639 T8078 T8076 arg2Of 3A,(
R664 T885 T890 arg2Of family,considered
R6640 T8078 T8077 arg1Of 3A,Figure
R6641 T8079 T8076 arg3Of ),(
R6642 T8081 T8080 arg2Of order,In
R6643 T8083 T8080 arg3Of analyze,In
R6644 T8083 T8082 arg1Of analyze,to
R6645 T8085 T8083 arg2Of activity,analyze
R6646 T8085 T8084 arg1Of activity,transcriptional
R6647 T8090 T8083 arg1Of plasmids,analyze
R6648 T8090 T8087 arg1Of plasmids,the
R6649 T8090 T8088 arg1Of plasmids,luciferase
R665 T885 T892 arg1Of family,play
R6650 T8090 T8089 arg1Of plasmids,reporter
R6651 T8090 T8091 arg1Of plasmids,were
R6652 T8090 T8093 arg2Of plasmids,transfected
R6653 T8093 T8080 arg1Of transfected,In
R6654 T8093 T8086 arg1Of transfected,","
R6655 T8093 T8091 arg2Of transfected,were
R6656 T8093 T8092 arg1Of transfected,transiently
R6657 T8093 T8094 arg1Of transfected,into
R6658 T8096 T8094 arg2Of cells,into
R6659 T8096 T8095 arg1Of cells,A3.01 T
R666 T888 T886 arg2Of deaminases,of
R6660 T8098 T8097 arg1Of assays,Luciferase
R6661 T8098 T8099 arg1Of assays,revealed
R6662 T8099 T8109 arg1Of revealed,as
R6663 T8099 T8115 arg1Of revealed,","
R6664 T8099 T8116 modOf revealed,indicating
R6665 T8102 T8101 arg1Of increased,∼20-fold
R6666 T8104 T8099 arg2Of activity,revealed
R6667 T8104 T8100 arg1Of activity,a
R6668 T8104 T8102 arg1Of activity,increased
R6669 T8104 T8103 arg1Of activity,transcriptional
R667 T888 T887 arg1Of deaminases,cytidine
R6670 T8104 T8105 arg1Of activity,of
R6671 T8108 T8105 arg2Of sequence,of
R6672 T8108 T8106 arg1Of sequence,the
R6673 T8108 T8107 arg1Of sequence,1025 bp
R6674 T8110 T8109 arg2Of compared,as
R6675 T8110 T8111 arg1Of compared,to
R6676 T8114 T8111 arg2Of vector,to
R6677 T8114 T8112 arg1Of vector,the
R6678 T8114 T8113 arg1Of vector,empty
R6679 T8118 T8119 arg1Of we,had
R668 T890 T889 arg2Of considered,is
R6680 T8118 T8120 arg1Of we,identified
R6681 T8120 T8116 arg2Of identified,indicating
R6682 T8120 T8117 arg1Of identified,that
R6683 T8120 T8119 arg2Of identified,had
R6684 T8125 T8120 arg2Of sequence,identified
R6685 T8125 T8121 arg1Of sequence,an
R6686 T8125 T8122 arg1Of sequence,active
R6687 T8125 T8123 arg1Of sequence,A3G
R6688 T8125 T8124 arg1Of sequence,promoter
R6689 T8125 T8126 arg1Of sequence,(
R669 T892 T890 arg3Of play,considered
R6690 T8128 T8126 arg2Of 3B,(
R6691 T8128 T8127 arg1Of 3B,Figure
R6692 T8129 T8126 arg3Of ),(
R6693 T8132 T8130 arg1Of rate,This
R6694 T8132 T8131 arg1Of rate,transcription
R6695 T8132 T8133 arg1Of rate,was
R6696 T8132 T8136 arg2Of rate,altered
R6697 T8136 T8133 arg2Of altered,was
R6698 T8136 T8134 arg1Of altered,not
R6699 T8136 T8135 arg1Of altered,significantly
R67 T98 T94 arg2Of family,of
R670 T892 T891 arg1Of play,to
R6700 T8140 T8136 arg1Of deletions,altered
R6701 T8140 T8137 arg2Of deletions,by
R6702 T8140 T8138 arg1Of deletions,the
R6703 T8140 T8139 arg1Of deletions,5′
R6704 T8140 T8141 arg1Of deletions,leading
R6705 T8141 T8142 arg1Of leading,to
R6706 T8144 T8145 arg1Of 502,","
R6707 T8145 T8147 arg1Of ",",and
R6708 T8146 T8145 arg2Of 225,","
R6709 T8148 T8147 arg2Of 180 bp,and
R671 T892 T896 arg1Of play,in
R6710 T8149 T8142 arg2Of fragments,to
R6711 T8149 T8143 arg1Of fragments,the
R6712 T8149 T8144 arg1Of fragments,502
R6713 T8149 T8146 arg1Of fragments,225
R6714 T8149 T8148 arg1Of fragments,180 bp
R6715 T8149 T8150 arg1Of fragments,(
R6716 T8152 T8150 arg2Of 3B,(
R6717 T8152 T8151 arg1Of 3B,Figure
R6718 T8153 T8150 arg3Of ),(
R6719 T8155 T8154 arg2Of contrast,In
R672 T895 T892 arg2Of role,play
R6720 T8158 T8157 arg1Of drop,a
R6721 T8158 T8159 arg1Of drop,in
R6722 T8158 T8162 arg1Of drop,was
R6723 T8158 T8163 arg2Of drop,observed
R6724 T8161 T8159 arg2Of activity,in
R6725 T8161 T8160 arg1Of activity,luciferase
R6726 T8163 T8154 arg1Of observed,In
R6727 T8163 T8156 arg1Of observed,","
R6728 T8163 T8162 arg2Of observed,was
R6729 T8163 T8164 arg1Of observed,in
R673 T895 T893 arg1Of role,an
R6730 T8166 T8164 arg2Of case,in
R6731 T8166 T8165 arg1Of case,the
R6732 T8166 T8167 arg1Of case,of
R6733 T8170 T8167 arg2Of fragment,of
R6734 T8170 T8168 arg1Of fragment,the
R6735 T8170 T8169 arg1Of fragment,150 bp
R6736 T8172 T8171 arg1Of construct,This
R6737 T8172 T8174 arg1Of construct,retained
R6738 T8174 T8173 arg1Of retained,only
R6739 T8174 T8188 arg1Of retained,and
R674 T895 T894 arg1Of role,important
R6740 T8176 T8174 arg2Of %,retained
R6741 T8176 T8175 arg1Of %,28
R6742 T8176 T8177 arg1Of %,of
R6743 T8180 T8177 arg2Of activity,of
R6744 T8180 T8178 arg1Of activity,the
R6745 T8180 T8179 arg1Of activity,transcriptional
R6746 T8180 T8181 arg1Of activity,of
R6747 T8180 T8185 arg1Of activity,in
R6748 T8184 T8181 arg2Of promoter,of
R6749 T8184 T8182 arg1Of promoter,the
R675 T899 T896 arg2Of immunity,in
R6750 T8184 T8183 arg1Of promoter,180 bp
R6751 T8187 T8185 arg2Of cells,in
R6752 T8187 T8186 arg1Of cells,A3.01 T
R6753 T8189 T8190 arg1Of activity,of
R6754 T8189 T8194 arg1Of activity,was
R6755 T8189 T8196 arg2Of activity,reduced
R6756 T8193 T8190 arg2Of fragment,of
R6757 T8193 T8191 arg1Of fragment,the
R6758 T8193 T8192 arg1Of fragment,120 bp
R6759 T8196 T8188 arg2Of reduced,and
R676 T899 T897 arg1Of immunity,antiviral
R6760 T8196 T8194 arg2Of reduced,was
R6761 T8196 T8195 arg1Of reduced,further
R6762 T8198 T8197 arg1Of reductions,Comparable
R6763 T8198 T8199 arg1Of reductions,relative
R6764 T8198 T8206 arg1Of reductions,were
R6765 T8198 T8207 arg2Of reductions,observed
R6766 T8199 T8200 arg1Of relative,to
R6767 T8202 T8200 arg2Of activity,to
R6768 T8202 T8201 arg1Of activity,the
R6769 T8202 T8203 arg1Of activity,of
R677 T899 T898 arg1Of immunity,intrinsic
R6770 T8205 T8203 arg2Of fragment,of
R6771 T8205 T8204 arg1Of fragment,180 bp
R6772 T8207 T8206 arg2Of observed,were
R6773 T8207 T8208 arg1Of observed,in
R6774 T8207 T8226 arg1Of observed,","
R6775 T8207 T8227 modOf observed,indicating
R6776 T8213 T8209 arg1Of U937,the
R6777 T8213 T8210 arg1Of U937,myeloid
R6778 T8213 T8211 arg1Of U937,cell
R6779 T8213 T8212 arg1Of U937,line
R678 T899 T900 arg1Of immunity,(
R6780 T8213 T8214 arg1Of U937,and
R6781 T8214 T8208 arg2Of and,in
R6782 T8218 T8215 arg1Of lines,the
R6783 T8218 T8216 arg1Of lines,hepatic
R6784 T8218 T8217 arg1Of lines,cell
R6785 T8219 T8218 arg1Of HepG2,lines
R6786 T8219 T8220 arg1Of HepG2,and
R6787 T8220 T8214 arg2Of and,and
R6788 T8221 T8220 arg2Of Huh7,and
R6789 T8221 T8222 arg1Of Huh7,(
R679 T901 T900 arg2Of "1,2",(
R6790 T8224 T8222 arg2Of 3C,(
R6791 T8224 T8223 arg1Of 3C,Figure
R6792 T8225 T8222 arg3Of ),(
R6793 T8231 T8229 arg1Of promoter,the
R6794 T8231 T8230 arg1Of promoter,core
R6795 T8231 T8232 arg1Of promoter,of
R6796 T8231 T8234 arg1Of promoter,is
R6797 T8231 T8235 arg1Of promoter,located
R6798 T8233 T8232 arg2Of A3G,of
R6799 T8234 T8227 arg2Of is,indicating
R68 T98 T95 arg1Of family,the
R680 T902 T900 arg3Of ),(
R6800 T8234 T8228 arg1Of is,that
R6801 T8235 T8234 arg2Of located,is
R6802 T8235 T8236 arg1Of located,within
R6803 T8238 T8236 arg2Of region,within
R6804 T8238 T8237 arg1Of region,the
R6805 T8238 T8239 arg1Of region,−114/+66
R6806 T8238 T8241 arg1Of region,to
R6807 T8241 T8240 arg1Of to,relative
R6808 T8243 T8241 arg2Of TSS,to
R6809 T8243 T8242 arg1Of TSS,the
R681 T904 T903 arg2Of primates,In
R682 T908 T906 arg1Of paralogs,the
R683 T908 T907 arg1Of paralogs,seven
R684 T909 T910 arg1Of APOBEC3A,","
R685 T910 T912 arg1Of ",",","
R686 T911 T910 arg2Of B,","
R687 T912 T914 arg1Of ",",","
R688 T913 T912 arg2Of C,","
R689 T914 T916 arg1Of ",",","
R69 T98 T97 arg1Of family,discovered
R690 T915 T914 arg2Of DE,","
R691 T916 T918 arg1Of ",",","
R692 T917 T916 arg2Of F,","
R693 T918 T920 arg1Of ",",","
R694 T919 T918 arg2Of G,","
R695 T920 T908 arg1Of ",",paralogs
R696 T920 T925 arg1Of ",",have
R697 T920 T926 arg1Of ",",been
R698 T920 T927 arg2Of ",",described
R699 T921 T920 arg2Of H,","
R70 T98 T99 arg1Of family,of
R700 T921 T922 arg1Of H,(
R701 T923 T922 arg2Of A3A-H,(
R702 T924 T922 arg3Of ),(
R703 T927 T903 arg1Of described,In
R704 T927 T905 arg1Of described,","
R705 T927 T925 arg2Of described,have
R706 T927 T926 arg2Of described,been
R707 T927 T928 arg1Of described,(
R708 T927 T932 arg1Of described,and
R709 T929 T928 arg2Of 3,(
R71 T102 T99 arg2Of deaminases,of
R710 T930 T928 arg3Of ),(
R711 T932 T931 arg1Of and,","
R712 T933 T934 arg1Of they,appear
R713 T933 T936 arg1Of they,fulfill
R714 T934 T932 arg2Of appear,and
R715 T936 T934 arg2Of fulfill,appear
R716 T936 T935 arg1Of fulfill,to
R717 T938 T936 arg2Of functions,fulfill
R718 T938 T937 arg1Of functions,individual
R719 T940 T939 arg1Of APOBEC3G,Human
R72 T102 T100 arg1Of deaminases,human
R720 T940 T941 arg1Of APOBEC3G,(
R721 T940 T944 arg1Of APOBEC3G,","
R722 T940 T953 arg1Of APOBEC3G,has
R723 T940 T954 arg1Of APOBEC3G,been
R7231 T8866 T8867 arg1Of promoter,is
R7232 T8866 T8869 arg1Of promoter,inducible
R7233 T8866 T8864 arg1Of promoter,The
R7234 T8866 T8865 arg1Of promoter,A3G
R7235 T8867 T8868 arg1Of is,not
R7236 T8867 T8870 arg1Of is,in
R7237 T8869 T8867 arg2Of inducible,is
R7238 T8872 T8870 arg2Of cells,in
R7239 T8872 T8871 arg1Of cells,T
R724 T940 T955 arg2Of APOBEC3G,identified
R7240 T8874 T8873 arg2Of to,According
R7241 T8877 T8874 arg2Of knowledge,to
R7242 T8877 T8875 arg1Of knowledge,the
R7243 T8877 T8876 arg1Of knowledge,current
R7244 T8879 T8880 arg1Of APOBEC3G,plays
R7245 T8880 T8873 arg1Of plays,According
R7246 T8880 T8878 arg1Of plays,","
R7247 T8880 T8883 arg1Of plays,in
R7248 T8882 T8880 arg2Of role,plays
R7249 T8882 T8881 arg1Of role,a
R725 T942 T941 arg2Of A3G,(
R7250 T8886 T8883 arg2Of defence,in
R7251 T8886 T8884 arg1Of defence,the
R7252 T8886 T8885 arg1Of defence,innate
R7253 T8886 T8887 arg1Of defence,against
R7254 T8888 T8887 arg2Of pathogens,against
R7255 T8888 T8889 arg1Of pathogens,like
R7256 T8890 T8889 arg2Of HIV-1,like
R7257 T8892 T8891 arg1Of latter,The
R7258 T8892 T8893 arg1Of latter,has
R7259 T8892 T8894 arg1Of latter,evolved
R726 T943 T941 arg3Of ),(
R7260 T8894 T8893 arg2Of evolved,has
R7261 T8896 T8894 arg2Of mechanism,evolved
R7262 T8896 T8895 arg1Of mechanism,a
R7263 T8896 T8897 modOf mechanism,to
R7264 T8898 T8897 arg1Of counteract,to
R7265 T8898 T8901 arg1Of counteract,by
R7266 T8900 T8898 arg2Of activity,counteract
R7267 T8900 T8899 arg1Of activity,A3G
R7268 T8902 T8901 arg2Of expressing,by
R7269 T8906 T8902 arg2Of Vif,expressing
R727 T947 T946 arg1Of prominent,most
R7270 T8906 T8903 arg1Of Vif,the
R7271 T8906 T8904 arg1Of Vif,regulatory
R7272 T8906 T8905 arg1Of Vif,protein
R7273 T8906 T8907 arg1Of Vif,(
R7274 T8908 T8907 arg2Of 4,(
R7275 T8909 T8907 arg3Of ),(
R7276 T8910 T8911 arg1Of Vif,induces
R7277 T8910 T8918 arg1Of Vif,inhibits
R7278 T8911 T8916 arg1Of induces,and
R7279 T8913 T8911 arg2Of degradation,induces
R728 T948 T944 arg2Of member,","
R7280 T8913 T8912 arg1Of degradation,proteasomal
R7281 T8913 T8914 arg1Of degradation,of
R7282 T8915 T8914 arg2Of A3G,of
R7283 T8918 T8916 arg2Of inhibits,and
R7284 T8918 T8917 arg1Of inhibits,additionally
R7285 T8920 T8918 arg2Of activity,inhibits
R7286 T8920 T8919 arg1Of activity,A3G
R7287 T8920 T8921 arg1Of activity,by
R7288 T8923 T8921 arg2Of mechanisms,by
R7289 T8923 T8922 arg1Of mechanisms,further
R729 T948 T945 arg1Of member,the
R7290 T8923 T8924 arg1Of mechanisms,(
R7291 T8925 T8924 arg2Of 8,(
R7292 T8925 T8926 arg1Of 8,","
R7293 T8927 T8926 arg2Of 37–43,","
R7294 T8928 T8924 arg3Of ),(
R7295 T8930 T8929 arg1Of investigate,To
R7296 T8933 T8932 arg1Of overexpression,the
R7297 T8933 T8934 arg1Of overexpression,of
R7298 T8933 T8938 arg1Of overexpression,influences
R7299 T8936 T8934 arg2Of proteins,of
R73 T102 T101 arg1Of deaminases,cytidine
R730 T948 T947 arg1Of member,prominent
R7300 T8936 T8935 arg1Of proteins,HIV-1
R7301 T8938 T8930 arg2Of influences,investigate
R7302 T8938 T8931 arg1Of influences,whether
R7303 T8938 T8937 arg1Of influences,also
R7304 T8941 T8938 arg2Of activity,influences
R7305 T8941 T8939 arg1Of activity,A3G
R7306 T8941 T8940 arg1Of activity,promoter
R7307 T8943 T8930 arg1Of we,investigate
R7308 T8943 T8945 arg1Of we,expressed
R7309 T8945 T8944 arg1Of expressed,either
R731 T948 T949 arg1Of member,of
R7310 T8945 T8953 arg1Of expressed,","
R7311 T8947 T8946 arg1Of Vif,HIV-1
R7312 T8947 T8948 arg1Of Vif,or
R7313 T8948 T8945 arg2Of or,expressed
R7314 T8952 T8948 arg2Of protein,or
R7315 T8952 T8949 arg1Of protein,the
R7316 T8952 T8950 arg1Of protein,HIV-1
R7317 T8952 T8951 arg1Of protein,Tat
R7318 T8953 T8929 modOf ",",To
R7319 T8953 T8942 arg1Of ",",","
R732 T952 T949 arg2Of family,of
R7320 T8955 T8954 arg1Of latter,the
R7321 T8955 T8956 arg1Of latter,has
R7322 T8955 T8957 arg1Of latter,been
R7323 T8955 T8958 arg2Of latter,shown
R7324 T8955 T8960 arg1Of latter,activate
R7325 T8958 T8953 arg2Of shown,","
R7326 T8958 T8956 arg2Of shown,has
R7327 T8958 T8957 arg2Of shown,been
R7328 T8960 T8958 arg3Of activate,shown
R7329 T8960 T8959 arg1Of activate,to
R733 T952 T950 arg1Of family,the
R7330 T8962 T8963 arg1Of viral,and
R7331 T8964 T8963 arg2Of cellular,and
R7332 T8965 T8960 arg2Of promoters,activate
R7333 T8965 T8961 arg1Of promoters,different
R7334 T8965 T8962 arg1Of promoters,viral
R7335 T8965 T8964 arg1Of promoters,cellular
R7336 T8965 T8966 arg1Of promoters,(
R7337 T8967 T8966 arg2Of "44,45",(
R7338 T8968 T8966 arg3Of ),(
R7339 T8970 T8969 arg2Of addition,In
R734 T952 T951 arg1Of family,APOBEC3
R7340 T8973 T8972 arg1Of amounts,increasing
R7341 T8973 T8974 arg1Of amounts,of
R7342 T8973 T8978 arg1Of amounts,","
R7343 T8973 T8979 arg1Of amounts,containing
R7344 T8973 T8986 arg1Of amounts,were
R7345 T8973 T8987 arg2Of amounts,transfected
R7346 T8977 T8974 arg2Of pNL4-3,of
R7347 T8977 T8975 arg1Of pNL4-3,the
R7348 T8977 T8976 arg1Of pNL4-3,plasmid
R7349 T8982 T8979 arg2Of genome,containing
R735 T955 T953 arg2Of identified,has
R7350 T8982 T8980 arg1Of genome,the
R7351 T8982 T8981 arg1Of genome,full-length
R7352 T8982 T8983 arg1Of genome,of
R7353 T8984 T8983 arg2Of HIV-1,of
R7354 T8987 T8969 arg1Of transfected,In
R7355 T8987 T8971 arg1Of transfected,","
R7356 T8987 T8985 arg1Of transfected,","
R7357 T8987 T8986 arg2Of transfected,were
R7358 T8989 T8988 arg1Of constructs,These
R7359 T8989 T8990 arg1Of constructs,or
R736 T955 T954 arg2Of identified,been
R7360 T8990 T8995 arg1Of or,were
R7361 T8990 T8996 arg2Of or,cotransfected
R7362 T8994 T8990 arg2Of pcDNA3.1,or
R7363 T8994 T8991 arg1Of pcDNA3.1,the
R7364 T8994 T8992 arg1Of pcDNA3.1,empty
R7365 T8994 T8993 arg1Of pcDNA3.1,vector
R7366 T8996 T8995 arg2Of cotransfected,were
R7367 T8996 T8997 arg1Of cotransfected,with
R7368 T9000 T8997 arg2Of construct,with
R7369 T9000 T8998 arg1Of construct,the
R737 T955 T956 arg1Of identified,as
R7370 T9000 T8999 arg1Of construct,1025 bp
R7371 T9000 T9001 arg1Of construct,into
R7372 T9003 T9001 arg2Of cells,into
R7373 T9003 T9002 arg1Of cells,A3.01 T
R7374 T9005 T9004 arg1Of assays,Luciferase
R7375 T9005 T9006 arg1Of assays,showed
R7376 T9010 T9008 arg1Of activity,the
R7377 T9010 T9009 arg1Of activity,transcriptional
R7378 T9010 T9011 arg1Of activity,of
R7379 T9010 T9015 arg1Of activity,was
R738 T960 T956 arg2Of factor,as
R7380 T9010 T9018 arg2Of activity,altered
R7381 T9014 T9011 arg2Of promoter,of
R7382 T9014 T9012 arg1Of promoter,the
R7383 T9014 T9013 arg1Of promoter,A3G
R7384 T9018 T9006 arg2Of altered,showed
R7385 T9018 T9007 arg1Of altered,that
R7386 T9018 T9015 arg2Of altered,was
R7387 T9018 T9016 arg1Of altered,not
R7388 T9018 T9017 arg1Of altered,significantly
R7389 T9018 T9019 arg1Of altered,in
R739 T960 T957 arg1Of factor,the
R7390 T9018 T9032 arg1Of altered,","
R7391 T9018 T9033 modOf altered,suggesting
R7392 T9021 T9019 arg2Of presence,in
R7393 T9021 T9020 arg1Of presence,the
R7394 T9021 T9022 arg1Of presence,of
R7395 T9023 T9024 arg1Of Vif,","
R7396 T9024 T9026 arg1Of ",",or
R7397 T9025 T9024 arg2Of Tat,","
R7398 T9026 T9022 arg2Of or,of
R7399 T9027 T9026 arg2Of HIV-1NL4-3,or
R74 T105 T104 arg2Of expressed,is
R740 T960 T958 arg1Of factor,cellular
R7400 T9027 T9028 arg1Of HIV-1NL4-3,(
R7401 T9030 T9028 arg2Of 4A,(
R7402 T9030 T9029 arg1Of 4A,Figure
R7403 T9031 T9028 arg3Of ),(
R7404 T9035 T9036 arg1Of HIV-1,is
R7405 T9035 T9038 arg1Of HIV-1,modulating
R7406 T9038 T9033 arg2Of modulating,suggesting
R7407 T9038 T9034 arg1Of modulating,that
R7408 T9038 T9036 arg2Of modulating,is
R7409 T9038 T9037 arg1Of modulating,not
R741 T960 T959 arg1Of factor,restriction
R7410 T9040 T9038 arg2Of expression,modulating
R7411 T9040 T9039 arg1Of expression,A3G
R7412 T9040 T9041 arg1Of expression,on
R7413 T9044 T9041 arg2Of level,on
R7414 T9044 T9042 arg1Of level,the
R7415 T9044 T9043 arg1Of level,transcriptional
R7416 T9045 T9046 arg1Of It,has
R7417 T9045 T9047 arg1Of It,been
R7418 T9045 T9048 arg2Of It,shown
R7419 T9048 T9046 arg2Of shown,has
R742 T960 T961 arg1Of factor,that
R7420 T9048 T9047 arg2Of shown,been
R7421 T9051 T9050 arg1Of amount,the
R7422 T9051 T9052 arg1Of amount,of
R7423 T9051 T9055 arg1Of amount,in
R7424 T9051 T9058 arg1Of amount,is
R7425 T9051 T9059 arg2Of amount,increased
R7426 T9054 T9052 arg2Of mRNA,of
R7427 T9054 T9053 arg1Of mRNA,A3G
R7428 T9057 T9055 arg2Of cells,in
R7429 T9057 T9056 arg1Of cells,T
R743 T960 T962 arg1Of factor,is
R7430 T9059 T9048 arg3Of increased,shown
R7431 T9059 T9049 arg1Of increased,that
R7432 T9059 T9058 arg2Of increased,is
R7433 T9059 T9060 arg1Of increased,in
R7434 T9060 T9062 arg1Of in,to
R7435 T9061 T9060 arg2Of response,in
R7436 T9064 T9060 arg3Of stimulation,in
R7437 T9064 T9063 arg1Of stimulation,mitogenic
R7438 T9064 T9065 arg1Of stimulation,with
R7439 T9067 T9065 arg2Of ester,with
R744 T960 T963 arg1Of factor,responsible
R7440 T9067 T9066 arg1Of ester,phorbol
R7441 T9067 T9068 arg1Of ester,(
R7442 T9069 T9068 arg2Of 46–48,(
R7443 T9070 T9068 arg3Of ),(
R7444 T9072 T9071 arg2Of addition,In
R7445 T9074 T9075 arg1Of interferons,have
R7446 T9074 T9076 arg1Of interferons,been
R7447 T9074 T9077 arg2Of interferons,described
R7448 T9074 T9079 arg1Of interferons,upregulate
R7449 T9077 T9071 arg1Of described,In
R745 T963 T962 arg2Of responsible,is
R7450 T9077 T9073 arg1Of described,","
R7451 T9077 T9075 arg2Of described,have
R7452 T9077 T9076 arg2Of described,been
R7453 T9079 T9077 arg3Of upregulate,described
R7454 T9079 T9078 arg1Of upregulate,to
R7455 T9081 T9079 arg2Of expression,upregulate
R7456 T9081 T9080 arg1Of expression,A3G
R7457 T9081 T9082 arg1Of expression,in
R7458 T9083 T9084 arg1Of hepatocytes,and
R7459 T9084 T9082 arg2Of and,in
R746 T963 T964 arg1Of responsible,for
R7460 T9084 T9086 arg1Of and,(
R7461 T9085 T9084 arg2Of macrophages,and
R7462 T9087 T9086 arg2Of "46,48",(
R7463 T9088 T9086 arg3Of ),(
R7464 T9090 T9089 arg1Of investigate,To
R7465 T9093 T9092 arg1Of stimuli,these
R7466 T9093 T9094 arg1Of stimuli,interfere
R7467 T9094 T9095 arg1Of interfere,with
R7468 T9094 T9102 arg1Of interfere,","
R7469 T9098 T9095 arg2Of activity,with
R747 T965 T964 arg2Of inhibition,for
R7470 T9098 T9096 arg1Of activity,A3G
R7471 T9098 T9097 arg1Of activity,promoter
R7472 T9098 T9099 arg1Of activity,in
R7473 T9101 T9099 arg2Of cells,in
R7474 T9101 T9100 arg1Of cells,T
R7475 T9102 T9090 arg1Of ",",investigate
R7476 T9102 T9091 arg1Of ",",whether
R7477 T9102 T9107 arg1Of ",",with
R7478 T9102 T9120 arg1Of ",",treated
R7479 T9103 T9104 arg1Of we,transfected
R748 T965 T966 arg1Of inhibition,of
R7480 T9104 T9102 arg2Of transfected,","
R7481 T9106 T9104 arg2Of cells,transfected
R7482 T9106 T9105 arg1Of cells,A3.01 T
R7483 T9110 T9108 arg1Of promoter,the
R7484 T9110 T9109 arg1Of promoter,1025 bp
R7485 T9110 T9111 arg1Of promoter,or
R7486 T9111 T9107 arg2Of or,with
R7487 T9114 T9111 arg2Of vector,or
R7488 T9114 T9112 arg1Of vector,the
R7489 T9114 T9113 arg1Of vector,empty
R749 T971 T970 arg2Of Vif,(
R7490 T9114 T9115 arg1Of vector,pGL3-Basic
R7491 T9114 T9116 arg1Of vector,(
R7492 T9114 T9119 arg1Of vector,and
R7493 T9117 T9116 arg2Of vector,(
R7494 T9118 T9116 arg3Of ),(
R7495 T9120 T9089 modOf treated,To
R7496 T9122 T9120 arg2Of cells,treated
R7497 T9122 T9121 arg1Of cells,the
R7498 T9122 T9123 arg1Of cells,with
R7499 T9125 T9123 arg2Of ester,with
R75 T105 T106 arg1Of expressed,in
R750 T972 T970 arg3Of ),(
R7500 T9125 T9124 arg1Of ester,phorbol
R7501 T9125 T9126 arg1Of ester,(
R7502 T9127 T9126 arg2Of TPA,(
R7503 T9128 T9126 arg3Of ),(
R7504 T9131 T9129 arg1Of assay,The
R7505 T9131 T9130 arg1Of assay,luciferase
R7506 T9131 T9132 arg1Of assay,showed
R7507 T9138 T9134 arg1Of activity,the
R7508 T9138 T9135 arg1Of activity,∼15-fold
R7509 T9138 T9136 arg2Of activity,increased
R751 T978 T977 arg2Of HIV-1,(
R7510 T9138 T9137 arg1Of activity,transcriptional
R7511 T9138 T9139 arg1Of activity,of
R7512 T9138 T9143 arg1Of activity,relative
R7513 T9138 T9148 arg1Of activity,was
R7514 T9138 T9151 arg2Of activity,enhanced
R7515 T9142 T9139 arg2Of promoter,of
R7516 T9142 T9140 arg1Of promoter,the
R7517 T9142 T9141 arg1Of promoter,1025 bp
R7518 T9143 T9144 arg1Of relative,to
R7519 T9147 T9144 arg2Of vector,to
R752 T979 T977 arg3Of ),(
R7520 T9147 T9145 arg1Of vector,the
R7521 T9147 T9146 arg1Of vector,empty
R7522 T9151 T9132 arg2Of enhanced,showed
R7523 T9151 T9133 arg1Of enhanced,that
R7524 T9151 T9148 arg2Of enhanced,was
R7525 T9151 T9149 arg1Of enhanced,not
R7526 T9151 T9150 arg1Of enhanced,further
R7527 T9151 T9159 arg1Of enhanced,","
R7528 T9151 T9160 arg1Of enhanced,although
R7529 T9154 T9151 arg1Of treatment,enhanced
R753 T980 T966 arg2Of replication,of
R7530 T9154 T9152 arg2Of treatment,by
R7531 T9154 T9153 arg1Of treatment,TPA
R7532 T9154 T9155 arg1Of treatment,(
R7533 T9157 T9155 arg2Of 4B,(
R7534 T9157 T9156 arg1Of 4B,Figure
R7535 T9158 T9155 arg3Of ),(
R7536 T9163 T9161 arg1Of activity,the
R7537 T9163 T9162 arg1Of activity,functional
R7538 T9163 T9164 arg1Of activity,of
R7539 T9163 T9166 arg1Of activity,was
R754 T980 T967 arg1Of replication,virion
R7540 T9163 T9167 arg2Of activity,confirmed
R7541 T9165 T9164 arg2Of TPA,of
R7542 T9167 T9160 arg2Of confirmed,although
R7543 T9167 T9166 arg2Of confirmed,was
R7544 T9169 T9167 arg1Of induction,confirmed
R7545 T9169 T9168 arg2Of induction,by
R7546 T9169 T9170 arg1Of induction,of
R7547 T9176 T9170 arg2Of pGL3-Control,of
R7548 T9176 T9171 arg1Of pGL3-Control,the
R7549 T9176 T9172 arg1Of pGL3-Control,SV40
R755 T980 T968 arg1Of replication,infectivity
R7550 T9176 T9173 arg1Of pGL3-Control,promoter-containing
R7551 T9176 T9174 arg1Of pGL3-Control,reporter
R7552 T9176 T9175 arg1Of pGL3-Control,plasmid
R7553 T9176 T9177 arg1Of pGL3-Control,(
R7554 T9178 T9177 arg2Of data,(
R7555 T9178 T9180 arg2Of data,shown
R7556 T9180 T9179 arg1Of shown,not
R7557 T9181 T9177 arg3Of ),(
R7558 T9184 T9185 arg1Of treatment,of
R7559 T9184 T9199 arg1Of treatment,showed
R756 T980 T969 arg1Of replication,factor
R7560 T9187 T9185 arg2Of cells,of
R7561 T9187 T9186 arg1Of cells,A3.01 T
R7562 T9187 T9188 arg2Of cells,transfected
R7563 T9188 T9189 arg1Of transfected,with
R7564 T9194 T9189 arg2Of constructs,with
R7565 T9194 T9190 arg1Of constructs,the
R7566 T9194 T9191 arg1Of constructs,A3G
R7567 T9194 T9192 arg1Of constructs,promoter
R7568 T9194 T9193 arg1Of constructs,deletion
R7569 T9194 T9195 arg1Of constructs,with
R757 T980 T970 arg1Of replication,(
R7570 T9196 T9197 arg1Of IFN-α,or
R7571 T9197 T9195 arg2Of or,with
R7572 T9198 T9197 arg2Of IFN-γ,or
R7573 T9199 T9182 arg1Of showed,Similarly
R7574 T9199 T9183 arg1Of showed,","
R7575 T9201 T9199 arg2Of effect,showed
R7576 T9201 T9200 arg1Of effect,no
R7577 T9201 T9202 arg1Of effect,(
R7578 T9204 T9202 arg2Of 4C,(
R7579 T9204 T9203 arg1Of 4C,Figure
R758 T980 T973 arg1Of replication,-deleted
R7580 T9205 T9202 arg3Of ),(
R7581 T9210 T9208 arg1Of plasmid,a
R7582 T9210 T9209 arg1Of plasmid,control
R7583 T9210 T9211 arg1Of plasmid,(
R7584 T9210 T9214 arg1Of plasmid,containing
R7585 T9210 T9230 arg1Of plasmid,was
R7586 T9210 T9232 arg2Of plasmid,induced
R7587 T9212 T9211 arg2Of pGL2-CVX,(
R7588 T9213 T9211 arg3Of ),(
R7589 T9219 T9218 arg2Of gamma,(
R759 T980 T974 arg1Of replication,human
R7590 T9219 T9220 arg2Of gamma,activated
R7591 T9221 T9220 arg3Of sequence,activated
R7592 T9222 T9218 arg3Of ),(
R7593 T9223 T9214 arg2Of elements,containing
R7594 T9223 T9215 arg1Of elements,two
R7595 T9223 T9216 arg1Of elements,IFN-responsive
R7596 T9223 T9217 arg1Of elements,GAS
R7597 T9223 T9218 arg1Of elements,(
R7598 T9223 T9224 arg1Of elements,upstream
R7599 T9224 T9225 arg1Of upstream,of
R76 T105 T110 arg1Of expressed,and
R760 T980 T975 arg1Of replication,immunodeficiency
R7600 T9229 T9225 arg2Of gene,of
R7601 T9229 T9226 arg1Of gene,the
R7602 T9229 T9227 arg1Of gene,luciferase
R7603 T9229 T9228 arg1Of gene,reporter
R7604 T9232 T9206 arg1Of induced,Interestingly
R7605 T9232 T9207 arg1Of induced,","
R7606 T9232 T9230 arg2Of induced,was
R7607 T9232 T9231 arg1Of induced,only
R7608 T9232 T9235 arg1Of induced,in
R7609 T9234 T9232 arg1Of IFN-α,induced
R761 T980 T976 arg1Of replication,virus-1
R7610 T9234 T9233 arg2Of IFN-α,by
R7611 T9237 T9235 arg2Of cells,in
R7612 T9237 T9236 arg1Of cells,these
R7613 T9237 T9238 arg1Of cells,(
R7614 T9240 T9238 arg2Of 4C,(
R7615 T9240 T9239 arg1Of 4C,Figure
R7616 T9241 T9238 arg3Of ),(
R7617 T9244 T9243 arg1Of reports,two
R7618 T9244 T9245 arg1Of reports,describe
R7619 T9245 T9242 arg2Of describe,Since
R762 T980 T977 arg1Of replication,(
R7620 T9247 T9245 arg2Of upregulation,describe
R7621 T9247 T9246 arg1Of upregulation,A3G
R7622 T9247 T9248 arg1Of upregulation,by
R7623 T9249 T9248 arg2Of interferons,by
R7624 T9249 T9250 arg1Of interferons,in
R7625 T9251 T9250 arg2Of hepatocytes,in
R7626 T9251 T9252 arg1Of hepatocytes,(
R7627 T9253 T9252 arg2Of "47,48",(
R7628 T9254 T9252 arg3Of ),(
R7629 T9256 T9258 arg1Of we,performed
R763 T980 T981 arg1Of replication,in
R7630 T9258 T9242 arg1Of performed,Since
R7631 T9258 T9255 arg1Of performed,","
R7632 T9258 T9257 arg1Of performed,additionally
R7633 T9260 T9258 arg2Of experiment,performed
R7634 T9260 T9259 arg1Of experiment,the
R7635 T9260 T9261 arg1Of experiment,in
R7636 T9266 T9261 arg2Of HepG2,in
R7637 T9266 T9262 arg1Of HepG2,the
R7638 T9266 T9263 arg1Of HepG2,hepatic
R7639 T9266 T9264 arg1Of HepG2,cell
R764 T983 T981 arg2Of cells,in
R7640 T9266 T9265 arg1Of HepG2,line
R7641 T9268 T9267 arg2Of line,In
R7642 T9268 T9269 arg1Of line,with
R7643 T9271 T9269 arg2Of publications,with
R7644 T9271 T9270 arg1Of publications,these
R7645 T9273 T9274 arg1Of we,observed
R7646 T9274 T9267 arg1Of observed,In
R7647 T9274 T9272 arg1Of observed,","
R7648 T9274 T9281 arg1Of observed,by
R7649 T9274 T9284 arg1Of observed,after
R765 T983 T982 arg1Of cells,non-permissive
R7650 T9274 T9293 arg1Of observed,with
R7651 T9276 T9274 arg2Of induction,observed
R7652 T9276 T9275 arg1Of induction,an
R7653 T9276 T9277 arg1Of induction,of
R7654 T9280 T9277 arg2Of promoter,of
R7655 T9280 T9278 arg1Of promoter,the
R7656 T9280 T9279 arg1Of promoter,A3G
R7657 T9283 T9281 arg2Of 2-fold,by
R7658 T9283 T9282 arg1Of 2-fold,approximately
R7659 T9285 T9286 arg1Of IFN-α,or
R766 T983 T984 arg1Of cells,(
R7660 T9287 T9286 arg2Of IFN-γ,or
R7661 T9288 T9284 arg2Of stimulation,after
R7662 T9288 T9285 arg1Of stimulation,IFN-α
R7663 T9288 T9287 arg1Of stimulation,IFN-γ
R7664 T9288 T9289 arg1Of stimulation,(
R7665 T9291 T9289 arg2Of 4D,(
R7666 T9291 T9290 arg1Of 4D,Figure
R7667 T9292 T9289 arg3Of ),(
R7668 T9294 T9293 arg2Of IFN-γ,with
R7669 T9294 T9295 arg1Of IFN-γ,being
R767 T985 T984 arg2Of 4,(
R7670 T9294 T9298 arg1Of IFN-γ,potent
R7671 T9295 T9293 arg3Of being,with
R7672 T9298 T9295 arg2Of potent,being
R7673 T9298 T9296 arg1Of potent,slightly
R7674 T9298 T9297 arg1Of potent,more
R7675 T9302 T9299 arg2Of types,For
R7676 T9302 T9300 arg1Of types,both
R7677 T9302 T9301 arg1Of types,interferon
R7678 T9304 T9305 arg1Of induction,of
R7679 T9304 T9309 arg1Of induction,was
R768 T986 T984 arg3Of ),(
R7680 T9304 T9310 arg2Of induction,observed
R7681 T9308 T9305 arg2Of activity,of
R7682 T9308 T9306 arg1Of activity,A3G
R7683 T9308 T9307 arg1Of activity,promoter
R7684 T9310 T9299 arg1Of observed,For
R7685 T9310 T9303 arg1Of observed,","
R7686 T9310 T9309 arg2Of observed,was
R7687 T9310 T9311 arg1Of observed,for
R7688 T9310 T9320 arg1Of observed,","
R7689 T9310 T9321 modOf observed,indicating
R769 T987 T988 arg1Of A3G,is
R7690 T9314 T9311 arg2Of constructs,for
R7691 T9314 T9312 arg1Of constructs,all
R7692 T9314 T9313 arg1Of constructs,deletion
R7693 T9314 T9316 arg1Of constructs,for
R7694 T9316 T9315 arg1Of for,except
R7695 T9319 T9316 arg2Of fragment,for
R7696 T9319 T9317 arg1Of fragment,the
R7697 T9319 T9318 arg1Of fragment,60 bp
R7698 T9325 T9323 arg1Of region,the
R7699 T9325 T9324 arg1Of region,responsible
R77 T109 T106 arg2Of lymphocytes,in
R770 T987 T989 arg2Of A3G,packaged
R7700 T9325 T9326 arg1Of region,is
R7701 T9325 T9327 arg1Of region,located
R7702 T9326 T9321 arg2Of is,indicating
R7703 T9326 T9322 arg1Of is,that
R7704 T9327 T9326 arg2Of located,is
R7705 T9327 T9328 arg1Of located,within
R7706 T9330 T9328 arg2Of 60 nt,within
R7707 T9330 T9329 arg1Of 60 nt,the
R7708 T9330 T9331 arg1Of 60 nt,present
R7709 T9331 T9332 arg1Of present,in
R771 T987 T994 arg1Of A3G,causes
R7710 T9331 T9338 arg1Of present,in
R7711 T9332 T9336 arg1Of in,but
R7712 T9334 T9332 arg2Of 120 bp,in
R7713 T9334 T9333 arg1Of 120 bp,the
R7714 T9336 T9335 arg1Of but,","
R7715 T9338 T9336 arg2Of in,but
R7716 T9338 T9337 arg1Of in,not
R7717 T9341 T9338 arg2Of fragment,in
R7718 T9341 T9339 arg1Of fragment,the
R7719 T9341 T9340 arg1Of fragment,60 bp
R772 T989 T988 arg2Of packaged,is
R773 T989 T990 arg1Of packaged,into
R774 T989 T993 arg1Of packaged,and
R775 T992 T990 arg2Of particles,into
R776 T992 T991 arg1Of particles,HIV-1Δvif
R777 T994 T993 arg2Of causes,and
R778 T994 T1002 arg1Of causes,during
R779 T996 T994 arg2Of deaminations,causes
R78 T109 T107 arg1Of lymphocytes,peripheral
R780 T996 T995 arg1Of deaminations,C-to-U
R781 T996 T997 arg1Of deaminations,on
R782 T1001 T997 arg2Of DNA,on
R783 T1001 T998 arg1Of DNA,the
R784 T1001 T999 arg1Of DNA,single-stranded
R785 T1001 T1000 arg1Of DNA,viral
R786 T1004 T1002 arg2Of transcription,during
R787 T1004 T1003 arg1Of transcription,reverse
R788 T1004 T1005 arg1Of transcription,(
R789 T1006 T1005 arg2Of 5–8,(
R79 T109 T108 arg1Of lymphocytes,blood
R790 T1007 T1005 arg3Of ),(
R791 T1008 T1009 arg1Of This,leads
R792 T1009 T1010 arg1Of leads,to
R793 T1011 T1010 arg2Of degradation,to
R794 T1011 T1012 arg1Of degradation,of
R795 T1015 T1012 arg2Of DNA,of
R796 T1015 T1013 arg1Of DNA,the
R797 T1015 T1014 arg1Of DNA,uracile-containing
R798 T1015 T1016 arg1Of DNA,by
R799 T1015 T1021 arg1Of DNA,to
R80 T110 T103 arg1Of and,","
R800 T1016 T1020 arg1Of by,or
R801 T1019 T1016 arg2Of mechanisms,by
R802 T1019 T1017 arg1Of mechanisms,cellular
R803 T1019 T1018 arg1Of mechanisms,repair
R804 T1021 T1020 arg2Of to,or
R805 T1022 T1021 arg2Of hypermutation,to
R806 T1022 T1023 arg1Of hypermutation,of
R807 T1026 T1023 arg2Of genome,of
R808 T1026 T1024 arg1Of genome,the
R809 T1026 T1025 arg1Of genome,viral
R81 T113 T110 arg2Of shown,and
R810 T1026 T1027 arg1Of genome,(
R811 T1028 T1027 arg2Of "5,6",(
R812 T1029 T1027 arg3Of ),(
R813 T1032 T1030 arg2Of result,As
R814 T1032 T1031 arg1Of result,a
R815 T1037 T1034 arg1Of fraction,only
R816 T1037 T1035 arg1Of fraction,a
R817 T1037 T1036 arg1Of fraction,marginal
R818 T1037 T1038 arg1Of fraction,of
R819 T1037 T1043 arg1Of fraction,is
R82 T113 T111 arg2Of shown,has
R820 T1037 T1044 arg1Of fraction,able
R821 T1037 T1046 arg1Of fraction,complete
R822 T1042 T1038 arg2Of particles,of
R823 T1042 T1039 arg1Of particles,the
R824 T1042 T1040 arg1Of particles,A3G-containing
R825 T1042 T1041 arg1Of particles,HIV-1
R826 T1043 T1030 arg1Of is,As
R827 T1043 T1033 arg1Of is,","
R828 T1044 T1043 arg2Of able,is
R829 T1046 T1044 arg2Of complete,able
R83 T113 T112 arg2Of shown,been
R830 T1046 T1045 arg1Of complete,to
R831 T1049 T1046 arg2Of cycle,complete
R832 T1049 T1047 arg1Of cycle,the
R833 T1049 T1048 arg1Of cycle,replication
R834 T1050 T1052 arg1Of In,to
R835 T1051 T1050 arg2Of addition,In
R836 T1054 T1050 arg3Of inhibition,In
R837 T1054 T1053 arg1Of inhibition,the
R838 T1054 T1055 arg1Of inhibition,of
R8383 T10346 T10345 arg1Of GC-box,A
R8384 T10346 T10347 arg1Of GC-box,located
R8385 T10346 T10355 arg1Of GC-box,is
R8386 T10346 T10356 arg1Of GC-box,important
R8387 T10347 T10348 arg1Of located,at
R8388 T10349 T10348 arg2Of position,at
R8389 T10349 T10350 arg1Of position,−87/−78
R839 T1056 T1055 arg2Of HIV-1,of
R8390 T10349 T10351 arg1Of position,of
R8391 T10354 T10351 arg2Of promoter,of
R8392 T10354 T10352 arg1Of promoter,the
R8393 T10354 T10353 arg1Of promoter,A3G
R8394 T10356 T10355 arg2Of important,is
R8395 T10356 T10357 arg1Of important,for
R8396 T10359 T10357 arg2Of activity,for
R8397 T10359 T10358 arg1Of activity,transcriptional
R8398 T10362 T10360 arg1Of studies,The
R8399 T10362 T10361 arg1Of studies,reporter
R84 T115 T113 arg3Of be,shown
R840 T1058 T1059 arg1Of A3G,restricts
R8400 T10362 T10363 arg2Of studies,shown
R8401 T10362 T10367 arg1Of studies,had
R8402 T10362 T10368 arg1Of studies,demonstrated
R8403 T10363 T10364 arg1Of shown,in
R8404 T10365 T10364 arg2Of Figure,in
R8405 T10365 T10366 arg1Of Figure,3
R8406 T10368 T10367 arg2Of demonstrated,had
R8407 T10368 T10374 arg1Of demonstrated,after
R8408 T10370 T10368 arg2Of drop,demonstrated
R8409 T10370 T10369 arg1Of drop,a
R841 T1059 T1050 arg1Of restricts,In
R8410 T10370 T10371 arg1Of drop,in
R8411 T10373 T10371 arg2Of activity,in
R8412 T10373 T10372 arg1Of activity,luciferase
R8413 T10375 T10374 arg2Of deletion,after
R8414 T10375 T10376 arg1Of deletion,of
R8415 T10375 T10379 arg1Of deletion,at
R8416 T10378 T10376 arg2Of 30 nt,of
R8417 T10378 T10377 arg1Of 30 nt,the
R8418 T10382 T10379 arg2Of end,at
R8419 T10382 T10380 arg1Of end,the
R842 T1059 T1057 arg1Of restricts,","
R8420 T10382 T10381 arg1Of end,5′
R8421 T10382 T10383 arg1Of end,of
R8422 T10387 T10383 arg2Of promoter,of
R8423 T10387 T10384 arg1Of promoter,the
R8424 T10387 T10385 arg1Of promoter,180 bp
R8425 T10387 T10386 arg1Of promoter,core
R8426 T10388 T10390 arg1Of We,inspected
R8427 T10388 T10400 arg1Of We,identified
R8428 T10390 T10399 arg1Of inspected,and
R8429 T10393 T10390 arg2Of sequence,inspected
R843 T1060 T1059 arg2Of replication,restricts
R8430 T10393 T10391 arg1Of sequence,the
R8431 T10393 T10392 arg1Of sequence,30 bp
R8432 T10393 T10394 arg2Of sequence,deleted
R8433 T10394 T10395 arg1Of deleted,in
R8434 T10398 T10395 arg2Of fragment,in
R8435 T10398 T10396 arg1Of fragment,the
R8436 T10398 T10397 arg1Of fragment,150 bp
R8437 T10399 T10389 arg1Of and,therefore
R8438 T10400 T10399 arg2Of identified,and
R8439 T10400 T10406 arg1Of identified,(
R844 T1060 T1061 arg1Of replication,of
R8440 T10402 T10400 arg2Of GC-box,identified
R8441 T10402 T10401 arg1Of GC-box,a
R8442 T10402 T10403 arg1Of GC-box,at
R8443 T10404 T10403 arg2Of position,at
R8444 T10404 T10405 arg1Of position,−87/−78
R8445 T10407 T10406 arg2Of see,(
R8446 T10408 T10407 arg2Of Figure,see
R8447 T10408 T10409 arg1Of Figure,1
R8448 T10410 T10406 arg3Of ),(
R8449 T10413 T10411 arg1Of TGGGCGGGAC,The
R845 T1063 T1062 arg1Of lentiviruses,other
R8450 T10413 T10412 arg1Of TGGGCGGGAC,sequence
R8451 T10413 T10414 arg1Of TGGGCGGGAC,","
R8452 T10413 T10415 arg1Of TGGGCGGGAC,which
R8453 T10413 T10416 arg1Of TGGGCGGGAC,is
R8454 T10413 T10417 arg2Of TGGGCGGGAC,interrupted
R8455 T10413 T10423 arg1Of TGGGCGGGAC,represents
R8456 T10417 T10416 arg2Of interrupted,is
R8457 T10417 T10418 arg1Of interrupted,in
R8458 T10421 T10418 arg2Of fragment,in
R8459 T10421 T10419 arg1Of fragment,the
R846 T1063 T1064 arg1Of lentiviruses,","
R8460 T10421 T10420 arg1Of fragment,150 bp
R8461 T10423 T10422 arg1Of represents,","
R8462 T10425 T10423 arg2Of variant,represents
R8463 T10425 T10424 arg1Of variant,a
R8464 T10425 T10426 arg1Of variant,of
R8465 T10429 T10428 arg2Of G/T,(
R8466 T10430 T10428 arg3Of ),(
R8467 T10431 T10428 arg1Of GGGCGG,(
R8468 T10431 T10432 arg1Of GGGCGG,(
R8469 T10431 T10435 arg1Of GGGCGG,(
R847 T1064 T1066 arg1Of ",",","
R8470 T10433 T10432 arg2Of G/A,(
R8471 T10434 T10432 arg3Of ),(
R8472 T10436 T10435 arg2Of G/A,(
R8473 T10437 T10435 arg3Of ),(
R8474 T10439 T10438 arg2Of C/T,(
R8475 T10440 T10438 arg3Of ),(
R8476 T10442 T10426 arg2Of motif,of
R8477 T10442 T10427 arg1Of motif,the
R8478 T10442 T10431 arg1Of motif,GGGCGG
R8479 T10442 T10438 arg1Of motif,(
R848 T1065 T1064 arg2Of gammaretroviruses,","
R8480 T10442 T10441 arg1Of motif,consensus
R8481 T10442 T10443 arg2Of motif,recognized
R8482 T10445 T10446 arg1Of Sp1,and
R8483 T10447 T10446 arg2Of Sp3,and
R8484 T10449 T10443 arg1Of factors,recognized
R8485 T10449 T10444 arg2Of factors,by
R8486 T10449 T10445 arg1Of factors,Sp1
R8487 T10449 T10447 arg1Of factors,Sp3
R8488 T10449 T10448 arg1Of factors,transcription
R8489 T10451 T10450 arg1Of analyze,To
R849 T1066 T1068 arg1Of ",",","
R8490 T10456 T10453 arg1Of site,this
R8491 T10456 T10454 arg1Of site,putative
R8492 T10456 T10455 arg1Of site,Sp1/Sp3-binding
R8493 T10456 T10457 arg1Of site,mediates
R8494 T10457 T10451 arg2Of mediates,analyze
R8495 T10457 T10452 arg1Of mediates,whether
R8496 T10459 T10457 arg2Of activity,mediates
R8497 T10459 T10458 arg1Of activity,transcriptional
R8498 T10459 T10460 arg1Of activity,of
R8499 T10464 T10460 arg2Of promoter,of
R85 T115 T114 arg1Of be,to
R850 T1067 T1066 arg2Of deltaretroviruses,","
R8500 T10464 T10461 arg1Of promoter,the
R8501 T10464 T10462 arg1Of promoter,180 bp
R8502 T10464 T10463 arg1Of promoter,core
R8503 T10466 T10451 arg1Of we,analyze
R8504 T10466 T10467 arg1Of we,introduced
R8505 T10467 T10450 modOf introduced,To
R8506 T10467 T10465 arg1Of introduced,","
R8507 T10470 T10467 arg2Of mutations,introduced
R8508 T10470 T10468 arg1Of mutations,two
R8509 T10470 T10469 arg1Of mutations,point
R851 T1068 T1061 arg2Of ",",of
R8510 T10470 T10471 arg1Of mutations,which
R8511 T10470 T10472 arg1Of mutations,changed
R8512 T10474 T10472 arg2Of sequence,changed
R8513 T10474 T10473 arg1Of sequence,the
R8514 T10474 T10475 arg1Of sequence,from
R8515 T10476 T10475 arg2Of TGGGCGGGAC,from
R8516 T10476 T10477 arg1Of TGGGCGGGAC,to
R8517 T10478 T10477 arg2Of TGTTCGGGAC,to
R8518 T10478 T10479 arg1Of TGTTCGGGAC,(
R8519 T10480 T10479 arg2Of mutations,(
R852 T1068 T1070 arg1Of ",",","
R8520 T10480 T10481 arg2Of mutations,shown
R8521 T10481 T10482 arg1Of shown,in
R8522 T10483 T10482 arg2Of bold,in
R8523 T10484 T10479 arg3Of ),(
R8524 T10485 T10486 arg1Of This,resulted
R8525 T10486 T10487 arg1Of resulted,in
R8526 T10486 T10496 arg1Of resulted,compared
R8527 T10486 T10506 arg1Of resulted,and
R8528 T10489 T10490 arg1Of 71,%
R8529 T10491 T10487 arg2Of reduction,in
R853 T1069 T1068 arg2Of spumaviruses,","
R8530 T10491 T10488 arg1Of reduction,a
R8531 T10491 T10489 arg1Of reduction,71
R8532 T10491 T10492 arg1Of reduction,of
R8533 T10495 T10492 arg2Of activity,of
R8534 T10495 T10493 arg1Of activity,the
R8535 T10495 T10494 arg1Of activity,transcriptional
R8536 T10497 T10496 arg2Of to,compared
R8537 T10501 T10497 arg2Of promoter,to
R8538 T10501 T10498 arg1Of promoter,the
R8539 T10501 T10499 arg1Of promoter,unmodified
R854 T1071 T1070 arg2Of long-terminal-repeat,","
R8540 T10501 T10500 arg1Of promoter,180 bp
R8541 T10501 T10502 arg1Of promoter,(
R8542 T10504 T10502 arg2Of 5A,(
R8543 T10504 T10503 arg1Of 5A,Figure
R8544 T10505 T10502 arg3Of ),(
R8545 T10508 T10507 arg1Of value,this
R8546 T10508 T10509 arg1Of value,was
R8547 T10508 T10512 arg1Of value,higher
R8548 T10509 T10506 arg2Of was,and
R8549 T10509 T10521 arg1Of was,","
R855 T1071 T1072 arg1Of long-terminal-repeat,(
R8550 T10509 T10522 modOf was,indicating
R8551 T10512 T10509 arg2Of higher,was
R8552 T10512 T10510 arg1Of higher,only
R8553 T10512 T10511 arg1Of higher,marginally
R8554 T10512 T10513 arg1Of higher,than
R8555 T10516 T10513 arg2Of activity,than
R8556 T10516 T10514 arg1Of activity,the
R8557 T10516 T10515 arg1Of activity,luciferase
R8558 T10516 T10517 arg1Of activity,of
R8559 T10520 T10517 arg2Of fragment,of
R856 T1073 T1072 arg2Of LTR,(
R8560 T10520 T10518 arg1Of fragment,the
R8561 T10520 T10519 arg1Of fragment,150 bp
R8562 T10526 T10524 arg1Of motif,the
R8563 T10526 T10525 arg2Of motif,identified
R8564 T10526 T10527 arg1Of motif,is
R8565 T10526 T10528 arg1Of motif,essential
R8566 T10527 T10522 arg2Of is,indicating
R8567 T10527 T10523 arg1Of is,that
R8568 T10528 T10527 arg2Of essential,is
R8569 T10528 T10529 arg1Of essential,for
R857 T1074 T1072 arg3Of ),(
R8570 T10531 T10529 arg2Of activity,for
R8571 T10531 T10530 arg1Of activity,basal
R8572 T10531 T10532 arg1Of activity,of
R8573 T10536 T10532 arg2Of promoter,of
R8574 T10536 T10533 arg1Of promoter,the
R8575 T10536 T10534 arg1Of promoter,A3G
R8576 T10536 T10535 arg1Of promoter,core
R8577 T10539 T10537 arg1Of examine,To
R8578 T10539 T10538 arg1Of examine,further
R8579 T10542 T10539 arg2Of potency,examine
R858 T1075 T1076 arg1Of -retrotransposons,","
R8580 T10542 T10540 arg1Of potency,the
R8581 T10542 T10541 arg1Of potency,transcriptional
R8582 T10542 T10543 arg1Of potency,of
R8583 T10545 T10543 arg2Of 30 nt,of
R8584 T10545 T10544 arg1Of 30 nt,the
R8585 T10545 T10546 arg1Of 30 nt,present
R8586 T10546 T10547 arg1Of present,in
R8587 T10550 T10547 arg2Of promoter,in
R8588 T10550 T10548 arg1Of promoter,the
R8589 T10550 T10549 arg1Of promoter,180 bp
R859 T1076 T1078 arg1Of ",",and
R8590 T10552 T10539 arg1Of we,examine
R8591 T10552 T10553 arg1Of we,cloned
R8592 T10553 T10537 modOf cloned,To
R8593 T10553 T10551 arg1Of cloned,","
R8594 T10553 T10590 arg1Of cloned,(
R8595 T10555 T10554 arg1Of region,the
R8596 T10555 T10556 arg1Of region,−114/−85
R8597 T10555 T10557 arg1Of region,(
R8598 T10555 T10572 arg1Of region,or
R8599 T10558 T10557 arg2Of containing,(
R86 T116 T115 arg2Of active,be
R860 T1077 T1076 arg2Of orthohepadnaviruses,","
R8600 T10560 T10558 arg2Of nucleotides,containing
R8601 T10560 T10559 arg1Of nucleotides,all
R8602 T10560 T10561 arg1Of nucleotides,which
R8603 T10560 T10562 arg1Of nucleotides,are
R8604 T10560 T10563 arg2Of nucleotides,deleted
R8605 T10560 T10568 arg1Of nucleotides,","
R8606 T10560 T10569 arg2Of nucleotides,designated
R8607 T10563 T10562 arg2Of deleted,are
R8608 T10563 T10564 arg1Of deleted,in
R8609 T10567 T10564 arg2Of fragment,in
R861 T1078 T1059 arg3Of and,restricts
R8610 T10567 T10565 arg1Of fragment,the
R8611 T10567 T10566 arg1Of fragment,150 bp
R8612 T10570 T10569 arg3Of E1,designated
R8613 T10571 T10557 arg3Of ),(
R8614 T10572 T10553 arg2Of or,cloned
R8615 T10574 T10572 arg2Of region,or
R8616 T10574 T10573 arg1Of region,the
R8617 T10574 T10575 arg1Of region,−92/−63
R8618 T10574 T10576 arg1Of region,(
R8619 T10574 T10586 arg1Of region,into
R862 T1078 T1080 arg1Of and,(
R8620 T10577 T10576 arg2Of containing,(
R8621 T10581 T10577 arg2Of motif,containing
R8622 T10581 T10578 arg1Of motif,the
R8623 T10581 T10579 arg1Of motif,putative
R8624 T10581 T10580 arg1Of motif,Sp1/Sp3
R8625 T10581 T10582 arg1Of motif,","
R8626 T10581 T10583 arg2Of motif,designated
R8627 T10584 T10583 arg3Of E2,designated
R8628 T10585 T10576 arg3Of ),(
R8629 T10589 T10586 arg2Of pGL3-Promoter,into
R863 T1079 T1078 arg2Of avihepadnaviruses,and
R8630 T10589 T10587 arg1Of pGL3-Promoter,the
R8631 T10589 T10588 arg1Of pGL3-Promoter,vector
R8632 T10591 T10590 arg2Of see,(
R8633 T10592 T10591 arg2Of Figure,see
R8634 T10592 T10593 arg1Of Figure,1
R8635 T10594 T10590 arg3Of ),(
R8636 T10596 T10595 arg1Of vector,This
R8637 T10596 T10597 arg1Of vector,contains
R8638 T10597 T10602 arg1Of contains,under
R8639 T10597 T10609 arg1Of contains,without
R864 T1081 T1080 arg2Of 9–21,(
R8640 T10597 T10613 arg1Of contains,and
R8641 T10601 T10597 arg2Of gene,contains
R8642 T10601 T10598 arg1Of gene,a
R8643 T10601 T10599 arg1Of gene,luciferase
R8644 T10601 T10600 arg1Of gene,reporter
R8645 T10604 T10602 arg2Of control,under
R8646 T10604 T10603 arg1Of control,the
R8647 T10604 T10605 arg1Of control,of
R8648 T10608 T10605 arg2Of promoter,of
R8649 T10608 T10606 arg1Of promoter,an
R865 T1082 T1080 arg3Of ),(
R8650 T10608 T10607 arg1Of promoter,SV40
R8651 T10611 T10609 arg2Of sequences,without
R8652 T10611 T10610 arg1Of sequences,enhancer
R8653 T10613 T10612 arg1Of and,","
R8654 T10617 T10614 arg1Of sequences,putative
R8655 T10617 T10615 arg1Of sequences,transcriptionally
R8656 T10617 T10616 arg1Of sequences,active
R8657 T10617 T10618 arg1Of sequences,can
R8658 T10617 T10619 arg1Of sequences,be
R8659 T10617 T10620 arg2Of sequences,cloned
R866 T1085 T1086 arg1Of deamination,seems
R8660 T10620 T10613 arg2Of cloned,and
R8661 T10620 T10618 arg2Of cloned,can
R8662 T10620 T10619 arg2Of cloned,be
R8663 T10620 T10621 arg1Of cloned,upstream
R8664 T10621 T10622 arg1Of upstream,of
R8665 T10625 T10622 arg2Of promoter,of
R8666 T10625 T10623 arg1Of promoter,the
R8667 T10625 T10624 arg1Of promoter,SV40
R8668 T10627 T10626 arg1Of assays,Luciferase
R8669 T10627 T10628 arg1Of assays,showed
R867 T1085 T1089 arg1Of deamination,be
R8670 T10632 T10630 arg1Of element,the
R8671 T10632 T10631 arg1Of element,E1
R8672 T10632 T10633 arg1Of element,increased
R8673 T10633 T10628 arg2Of increased,showed
R8674 T10633 T10629 arg1Of increased,that
R8675 T10633 T10638 arg1Of increased,by
R8676 T10636 T10633 arg2Of activity,increased
R8677 T10636 T10634 arg1Of activity,SV40
R8678 T10636 T10635 arg1Of activity,promoter
R8679 T10638 T10637 arg1Of by,only
R868 T1086 T1083 arg1Of seems,Interestingly
R8680 T10639 T10638 arg2Of ∼2-fold,by
R8681 T10639 T10640 arg1Of ∼2-fold,(
R8682 T10642 T10640 arg2Of 5B,(
R8683 T10642 T10641 arg1Of 5B,Figure
R8684 T10643 T10640 arg3Of ),(
R8685 T10645 T10644 arg2Of contrast,In
R8686 T10648 T10647 arg1Of 30 nt,the
R8687 T10648 T10649 arg1Of 30 nt,of
R8688 T10648 T10651 arg1Of 30 nt,enhanced
R8689 T10650 T10649 arg2Of E2,of
R869 T1086 T1084 arg1Of seems,","
R8690 T10651 T10644 arg1Of enhanced,In
R8691 T10651 T10646 arg1Of enhanced,","
R8692 T10651 T10661 arg1Of enhanced,","
R8693 T10651 T10662 modOf enhanced,indicating
R8694 T10654 T10651 arg2Of activity,enhanced
R8695 T10654 T10652 arg1Of activity,the
R8696 T10654 T10653 arg1Of activity,transcriptional
R8697 T10654 T10655 arg1Of activity,of
R8698 T10654 T10659 arg1Of activity,by
R8699 T10658 T10655 arg2Of promoter,of
R87 T116 T117 arg1Of active,against
R870 T1086 T1095 arg1Of seems,;
R8700 T10658 T10656 arg1Of promoter,the
R8701 T10658 T10657 arg1Of promoter,SV40
R8702 T10660 T10659 arg2Of ∼4.3-fold,by
R8703 T10666 T10664 arg1Of GC-box,the
R8704 T10666 T10665 arg1Of GC-box,intact
R8705 T10666 T10667 arg1Of GC-box,present
R8706 T10666 T10672 arg1Of GC-box,was
R8707 T10666 T10673 arg1Of GC-box,responsible
R8708 T10667 T10668 arg1Of present,in
R8709 T10671 T10668 arg2Of element,in
R871 T1089 T1086 arg2Of be,seems
R8710 T10671 T10669 arg1Of element,the
R8711 T10671 T10670 arg1Of element,E2
R8712 T10672 T10662 arg2Of was,indicating
R8713 T10672 T10663 arg1Of was,that
R8714 T10673 T10672 arg2Of responsible,was
R8715 T10673 T10674 arg1Of responsible,for
R8716 T10677 T10676 arg1Of enhanced,strongly
R8717 T10679 T10674 arg2Of activity,for
R8718 T10679 T10675 arg1Of activity,the
R8719 T10679 T10677 arg1Of activity,enhanced
R872 T1089 T1087 arg1Of be,not
R8720 T10679 T10678 arg1Of activity,transcriptional
R8721 T10679 T10680 arg1Of activity,of
R8722 T10683 T10680 arg2Of promoter,of
R8723 T10683 T10681 arg1Of promoter,the
R8724 T10683 T10682 arg1Of promoter,SV40
R873 T1089 T1088 arg1Of be,to
R874 T1094 T1089 arg2Of mechanism,be
R875 T1094 T1090 arg1Of mechanism,the
R876 T1094 T1091 arg1Of mechanism,only
R877 T1094 T1092 arg1Of mechanism,A3G-mediated
R878 T1094 T1093 arg1Of mechanism,antiviral
R879 T1098 T1096 arg2Of case,in
R88 T118 T119 arg1Of HIV-1,and
R880 T1098 T1097 arg1Of case,the
R881 T1098 T1099 arg1Of case,of
R882 T1102 T1100 arg1Of virus,hepatitis
R883 T1102 T1101 arg1Of virus,B
R884 T1102 T1103 arg1Of virus,(
R885 T1102 T1106 arg1Of virus,and
R886 T1104 T1103 arg2Of HBV,(
R887 T1105 T1103 arg3Of ),(
R888 T1106 T1099 arg2Of and,of
R889 T1112 T1106 arg2Of type,and
R89 T119 T117 arg2Of and,against
R890 T1112 T1107 arg1Of type,human
R891 T1112 T1108 arg1Of type,T
R892 T1112 T1109 arg1Of type,cell
R893 T1112 T1110 arg1Of type,leukemia
R894 T1112 T1111 arg1Of type,virus
R895 T1112 T1113 arg1Of type,1
R896 T1112 T1114 arg1Of type,(
R897 T1115 T1114 arg2Of HTLV-1,(
R898 T1116 T1114 arg3Of ),(
R899 T1118 T1119 arg1Of A3G,was
R90 T121 T119 arg2Of retroviruses,and
R900 T1118 T1120 arg2Of A3G,shown
R901 T1118 T1122 arg1Of A3G,restrict
R902 T1120 T1095 arg2Of shown,;
R903 T1120 T1096 arg1Of shown,in
R904 T1120 T1117 arg1Of shown,","
R905 T1120 T1119 arg2Of shown,was
R906 T1122 T1120 arg3Of restrict,shown
R907 T1122 T1121 arg1Of restrict,to
R908 T1122 T1125 arg1Of restrict,by
R909 T1124 T1122 arg2Of replication,restrict
R91 T121 T120 arg1Of retroviruses,other
R910 T1124 T1123 arg1Of replication,virus
R911 T1127 T1125 arg2Of mechanisms,by
R912 T1127 T1126 arg1Of mechanisms,deamination-independent
R913 T1127 T1128 arg1Of mechanisms,(
R914 T1129 T1130 arg1Of 12,","
R915 T1130 T1132 arg1Of ",",","
R916 T1131 T1130 arg2Of 13,","
R917 T1132 T1128 arg2Of ",",(
R918 T1132 T1134 arg1Of ",",","
R919 T1133 T1132 arg2Of 19,","
R92 T123 T122 arg1Of gain,To
R920 T1135 T1134 arg2Of 22–25,","
R921 T1136 T1128 arg3Of ),(
R922 T1138 T1137 arg1Of member,Another
R923 T1138 T1139 arg1Of member,of
R924 T1138 T1143 arg1Of member,","
R925 T1138 T1149 arg1Of member,appears
R9254 T11426 T11427 arg1Of Sp1,and
R9255 T11428 T11427 arg2Of Sp3,and
R9256 T11430 T11426 arg1Of factors,Sp1
R9257 T11430 T11428 arg1Of factors,Sp3
R9258 T11430 T11429 arg1Of factors,transcription
R9259 T11430 T11431 arg1Of factors,bind
R926 T1138 T1151 arg1Of member,have
R9260 T11431 T11432 arg1Of bind,to
R9261 T11434 T11432 arg2Of GC-box,to
R9262 T11434 T11433 arg1Of GC-box,the
R9263 T11434 T11435 arg1Of GC-box,at
R9264 T11436 T11435 arg2Of position,at
R9265 T11436 T11437 arg1Of position,−87/−78
R9266 T11436 T11438 arg1Of position,of
R9267 T11441 T11438 arg2Of promoter,of
R9268 T11441 T11439 arg1Of promoter,the
R9269 T11441 T11440 arg1Of promoter,A3G
R927 T1142 T1139 arg2Of family,of
R9270 T11443 T11442 arg1Of investigate,To
R9271 T11446 T11445 arg1Of GC-box,the
R9272 T11446 T11447 arg1Of GC-box,represents
R9273 T11447 T11443 arg2Of represents,investigate
R9274 T11447 T11444 arg1Of represents,whether
R9275 T11450 T11447 arg2Of site,represents
R9276 T11450 T11448 arg1Of site,a
R9277 T11450 T11449 arg1Of site,binding
R9278 T11450 T11451 arg1Of site,for
R9279 T11455 T11456 arg1Of Sp1,and
R928 T1142 T1140 arg1Of family,the
R9280 T11456 T11451 arg2Of and,for
R9281 T11456 T11452 arg1Of and,the
R9282 T11456 T11453 arg1Of and,transcription
R9283 T11456 T11454 arg1Of and,factors
R9284 T11457 T11456 arg2Of Sp3,and
R9285 T11459 T11443 arg1Of we,investigate
R9286 T11459 T11460 arg1Of we,performed
R9287 T11460 T11442 modOf performed,To
R9288 T11460 T11458 arg1Of performed,","
R9289 T11462 T11460 arg2Of analyses,performed
R929 T1142 T1141 arg1Of family,APOBEC3
R9290 T11462 T11461 arg1Of analyses,EMSA
R9291 T11462 T11463 arg1Of analyses,with
R9292 T11465 T11463 arg2Of extracts,with
R9293 T11465 T11464 arg1Of extracts,nuclear
R9294 T11465 T11466 arg2Of extracts,isolated
R9295 T11466 T11467 arg1Of isolated,from
R9296 T11469 T11467 arg2Of cells,from
R9297 T11469 T11468 arg1Of cells,A3.01 T
R9298 T11471 T11470 arg2Of probes,As
R9299 T11473 T11475 arg1Of we,labeled
R93 T125 T123 arg2Of insights,gain
R930 T1144 T1143 arg2Of APOBEC3F,","
R9300 T11475 T11470 arg1Of labeled,As
R9301 T11475 T11472 arg1Of labeled,","
R9302 T11475 T11474 arg1Of labeled,radioactively
R9303 T11479 T11476 arg1Of sequence,the
R9304 T11479 T11477 arg1Of sequence,unmodified
R9305 T11479 T11478 arg1Of sequence,E2
R9306 T11479 T11480 arg1Of sequence,(
R9307 T11479 T11492 arg1Of sequence,or
R9308 T11481 T11480 arg2Of nucleotides,(
R9309 T11481 T11482 arg1Of nucleotides,−92/−63
R931 T1144 T1145 arg1Of APOBEC3F,(
R9310 T11481 T11483 arg1Of nucleotides,of
R9311 T11486 T11483 arg2Of promoter,of
R9312 T11486 T11484 arg1Of promoter,the
R9313 T11486 T11485 arg1Of promoter,A3G
R9314 T11486 T11487 arg1Of promoter,","
R9315 T11488 T11487 arg2Of probe,","
R9316 T11488 T11489 arg2Of probe,designated
R9317 T11490 T11489 arg3Of APO-Sp1/3,designated
R9318 T11491 T11480 arg3Of ),(
R9319 T11492 T11475 arg2Of or,labeled
R932 T1146 T1145 arg2Of A3F,(
R9320 T11495 T11492 arg2Of region,or
R9321 T11495 T11493 arg1Of region,the
R9322 T11495 T11494 arg1Of region,same
R9323 T11495 T11496 arg1Of region,carrying
R9324 T11500 T11496 arg2Of mutations,carrying
R9325 T11500 T11497 arg1Of mutations,the
R9326 T11500 T11498 arg1Of mutations,two
R9327 T11500 T11499 arg1Of mutations,point
R9328 T11500 T11501 arg2Of mutations,described
R9329 T11501 T11502 arg1Of described,above
R933 T1147 T1145 arg3Of ),(
R9330 T11504 T11502 arg2Of probe,above
R9331 T11504 T11503 arg2Of probe,(
R9332 T11504 T11505 arg2Of probe,designated
R9333 T11506 T11505 arg3Of APO-Sp1/3mut,designated
R9334 T11507 T11503 arg3Of ),(
R9335 T11509 T11508 arg2Of control,As
R9336 T11511 T11512 arg1Of we,used
R9337 T11512 T11508 arg1Of used,As
R9338 T11512 T11510 arg1Of used,","
R9339 T11515 T11514 arg1Of available,commercially
R934 T1149 T1148 arg1Of appears,","
R9340 T11518 T11512 arg2Of oligonucleotide,used
R9341 T11518 T11513 arg1Of oligonucleotide,a
R9342 T11518 T11515 arg1Of oligonucleotide,available
R9343 T11518 T11516 arg1Of oligonucleotide,Sp1
R9344 T11518 T11517 arg1Of oligonucleotide,consensus
R9345 T11518 T11519 arg1Of oligonucleotide,(
R9346 T11518 T11522 arg1Of oligonucleotide,","
R9347 T11518 T11523 arg1Of oligonucleotide,which
R9348 T11518 T11524 arg1Of oligonucleotide,is
R9349 T11518 T11525 arg2Of oligonucleotide,known
R935 T1151 T1149 arg2Of have,appears
R9350 T11518 T11527 arg1Of oligonucleotide,be
R9351 T11518 T11528 arg2Of oligonucleotide,recognized
R9352 T11520 T11519 arg2Of Sp1cons,(
R9353 T11521 T11519 arg3Of ),(
R9354 T11525 T11524 arg2Of known,is
R9355 T11528 T11525 arg3Of recognized,known
R9356 T11528 T11526 arg1Of recognized,to
R9357 T11528 T11527 arg2Of recognized,be
R9358 T11532 T11528 arg1Of factors,recognized
R9359 T11532 T11529 arg2Of factors,by
R936 T1151 T1150 arg1Of have,to
R9360 T11532 T11530 arg1Of factors,Sp1
R9361 T11532 T11531 arg1Of factors,transcription
R9362 T11535 T11533 arg1Of complexes,Four
R9363 T11535 T11534 arg1Of complexes,DNA–protein
R9364 T11535 T11536 arg1Of complexes,were
R9365 T11535 T11537 arg2Of complexes,observed
R9366 T11537 T11536 arg2Of observed,were
R9367 T11537 T11538 arg1Of observed,in
R9368 T11540 T11538 arg2Of presence,in
R9369 T11540 T11539 arg1Of presence,the
R937 T1153 T1151 arg2Of activities,have
R9370 T11540 T11541 arg1Of presence,of
R9371 T11544 T11541 arg2Of probe,of
R9372 T11544 T11542 arg1Of probe,the
R9373 T11544 T11543 arg1Of probe,APO-Sp1/3
R9374 T11544 T11545 arg1Of probe,(
R9375 T11547 T11545 arg2Of 6A,(
R9376 T11547 T11546 arg1Of 6A,Figure
R9377 T11548 T11545 arg3Of ),(
R9378 T11552 T11549 arg1Of complexes,The
R9379 T11552 T11550 arg1Of complexes,upper
R938 T1153 T1152 arg1Of activities,similar
R9380 T11552 T11551 arg1Of complexes,two
R9381 T11552 T11553 arg1Of complexes,were
R9382 T11552 T11554 arg1Of complexes,specific
R9383 T11553 T11555 arg1Of were,since
R9384 T11554 T11553 arg2Of specific,were
R9385 T11556 T11557 arg1Of they,disappeared
R9386 T11557 T11555 arg2Of disappeared,since
R9387 T11557 T11558 arg1Of disappeared,in
R9388 T11560 T11558 arg2Of presence,in
R9389 T11560 T11559 arg1Of presence,the
R939 T1153 T1154 arg1Of activities,like
R9390 T11560 T11561 arg1Of presence,of
R9391 T11565 T11561 arg2Of excess,of
R9392 T11565 T11562 arg1Of excess,a
R9393 T11565 T11563 arg1Of excess,30-fold
R9394 T11565 T11564 arg1Of excess,molar
R9395 T11565 T11566 arg1Of excess,of
R9396 T11569 T11566 arg2Of probe,of
R9397 T11569 T11567 arg1Of probe,unlabeled
R9398 T11569 T11568 arg1Of probe,APO-Sp1/3
R9399 T11569 T11570 arg1Of probe,(
R94 T125 T124 arg1Of insights,new
R940 T1155 T1154 arg2Of A3G,like
R9400 T11572 T11570 arg2Of 6A,(
R9401 T11572 T11571 arg1Of 6A,Figure
R9402 T11572 T11573 arg1Of 6A,","
R9403 T11574 T11573 arg2Of lane,","
R9404 T11574 T11575 arg1Of lane,7
R9405 T11576 T11570 arg3Of ),(
R9406 T11578 T11577 arg1Of confirmation,Further
R9407 T11578 T11579 arg1Of confirmation,of
R9408 T11578 T11586 arg1Of confirmation,was
R9409 T11578 T11587 arg2Of confirmation,demonstrated
R941 T1155 T1156 arg1Of A3G,(
R9410 T11581 T11579 arg2Of specificity,of
R9411 T11581 T11580 arg1Of specificity,the
R9412 T11581 T11582 arg1Of specificity,of
R9413 T11585 T11582 arg2Of complexes,of
R9414 T11585 T11583 arg1Of complexes,these
R9415 T11585 T11584 arg1Of complexes,DNA–protein
R9416 T11587 T11586 arg2Of demonstrated,was
R9417 T11590 T11587 arg1Of inability,demonstrated
R9418 T11590 T11588 arg2Of inability,by
R9419 T11590 T11589 arg1Of inability,the
R942 T1157 T1156 arg2Of "26,27",(
R9420 T11590 T11591 arg1Of inability,of
R9421 T11590 T11596 modOf inability,to
R9422 T11595 T11591 arg2Of probe,of
R9423 T11595 T11592 arg1Of probe,the
R9424 T11595 T11593 arg1Of probe,unlabeled
R9425 T11595 T11594 arg1Of probe,APO-Sp1/3mut
R9426 T11597 T11596 arg1Of abolish,to
R9427 T11598 T11597 arg2Of binding,abolish
R9428 T11598 T11599 arg1Of binding,(
R9429 T11601 T11599 arg2Of 6A,(
R943 T1158 T1156 arg3Of ),(
R9430 T11601 T11600 arg1Of 6A,Figure
R9431 T11601 T11602 arg1Of 6A,","
R9432 T11604 T11605 arg1Of 12,and
R9433 T11605 T11602 arg2Of and,","
R9434 T11605 T11603 arg1Of and,lanes
R9435 T11606 T11605 arg2Of 13,and
R9436 T11607 T11599 arg3Of ),(
R9437 T11609 T11608 arg2Of expected,As
R9438 T11614 T11611 arg1Of complexes,the
R9439 T11614 T11612 arg1Of complexes,two
R944 T1159 T1160 arg1Of A3F,is
R9440 T11614 T11613 arg1Of complexes,specific
R9441 T11614 T11615 arg1Of complexes,were
R9442 T11614 T11617 arg1Of complexes,present
R9443 T11615 T11608 arg1Of were,As
R9444 T11615 T11610 arg1Of were,","
R9445 T11615 T11616 arg1Of were,also
R9446 T11617 T11615 arg2Of present,were
R9447 T11617 T11618 arg1Of present,in
R9448 T11620 T11618 arg2Of case,in
R9449 T11620 T11619 arg1Of case,the
R945 T1159 T1162 arg2Of A3F,packaged
R9450 T11620 T11621 arg1Of case,of
R9451 T11625 T11621 arg2Of probe,of
R9452 T11625 T11622 arg1Of probe,the
R9453 T11625 T11623 arg1Of probe,Sp1cons
R9454 T11625 T11624 arg1Of probe,control
R9455 T11625 T11626 arg1Of probe,(
R9456 T11628 T11626 arg2Of 6A,(
R9457 T11628 T11627 arg1Of 6A,Figure
R9458 T11628 T11629 arg1Of 6A,","
R9459 T11631 T11632 arg1Of 2,and
R946 T1159 T1167 arg1Of A3F,induces
R9460 T11632 T11629 arg2Of and,","
R9461 T11632 T11630 arg1Of and,lanes
R9462 T11633 T11632 arg2Of 3,and
R9463 T11634 T11626 arg3Of ),(
R9464 T11636 T11635 arg2Of contrast,In
R9465 T11638 T11639 arg1Of none,of
R9466 T11638 T11643 arg1Of none,was
R9467 T11638 T11644 arg2Of none,observed
R9468 T11642 T11639 arg2Of complexes,of
R9469 T11642 T11640 arg1Of complexes,these
R947 T1162 T1160 arg2Of packaged,is
R9470 T11642 T11641 arg1Of complexes,specific
R9471 T11644 T11635 arg1Of observed,In
R9472 T11644 T11637 arg1Of observed,","
R9473 T11644 T11643 arg2Of observed,was
R9474 T11644 T11645 arg1Of observed,when
R9475 T11644 T11651 arg1Of observed,(
R9476 T11644 T11660 arg1Of observed,","
R9477 T11644 T11661 modOf observed,confirming
R9478 T11648 T11646 arg1Of probe,the
R9479 T11648 T11647 arg2Of probe,mutated
R948 T1162 T1161 arg1Of packaged,also
R9480 T11648 T11649 arg1Of probe,was
R9481 T11648 T11650 arg2Of probe,used
R9482 T11650 T11645 arg2Of used,when
R9483 T11650 T11649 arg2Of used,was
R9484 T11653 T11651 arg2Of 6A,(
R9485 T11653 T11652 arg1Of 6A,Figure
R9486 T11653 T11654 arg1Of 6A,","
R9487 T11656 T11657 arg1Of 10,and
R9488 T11657 T11654 arg2Of and,","
R9489 T11657 T11655 arg1Of and,lanes
R949 T1162 T1163 arg1Of packaged,into
R9490 T11658 T11657 arg2Of 11,and
R9491 T11659 T11651 arg3Of ),(
R9492 T11664 T11663 arg1Of binding,protein
R9493 T11664 T11665 arg1Of binding,was
R9494 T11664 T11666 arg1Of binding,dependent
R9495 T11665 T11661 arg2Of was,confirming
R9496 T11665 T11662 arg1Of was,that
R9497 T11666 T11665 arg2Of dependent,was
R9498 T11666 T11667 arg1Of dependent,on
R9499 T11670 T11667 arg2Of GC-box,on
R95 T125 T126 arg1Of insights,into
R950 T1162 T1166 arg1Of packaged,and
R9500 T11670 T11668 arg1Of GC-box,the
R9501 T11670 T11669 arg2Of GC-box,identified
R9502 T11672 T11671 arg2Of order,In
R9503 T11674 T11671 arg3Of characterize,In
R9504 T11674 T11673 arg1Of characterize,to
R9505 T11676 T11674 arg2Of complexes,characterize
R9506 T11676 T11675 arg1Of complexes,the
R9507 T11678 T11674 arg1Of we,characterize
R9508 T11678 T11679 arg1Of we,performed
R9509 T11679 T11671 arg1Of performed,In
R951 T1165 T1163 arg2Of particles,into
R9510 T11679 T11677 arg1Of performed,","
R9511 T11681 T11679 arg2Of experiments,performed
R9512 T11681 T11680 arg1Of experiments,supershift
R9513 T11681 T11682 arg1Of experiments,using
R9514 T11686 T11682 arg2Of antibodies,using
R9515 T11686 T11683 arg1Of antibodies,Sp1-
R9516 T11686 T11684 arg1Of antibodies,and
R9517 T11686 T11685 arg1Of antibodies,Sp3-specific
R9518 T11688 T11687 arg1Of upper,The
R9519 T11688 T11689 arg1Of upper,of
R952 T1165 T1164 arg1Of particles,HIV-1Δvif
R9520 T11688 T11703 arg1Of upper,shifted
R9521 T11691 T11689 arg2Of complexes,of
R9522 T11691 T11690 arg1Of complexes,the
R9523 T11691 T11692 arg1Of complexes,that
R9524 T11691 T11693 arg1Of complexes,appeared
R9525 T11693 T11694 arg1Of appeared,in
R9526 T11695 T11694 arg2Of combination,in
R9527 T11695 T11696 arg1Of combination,with
R9528 T11698 T11699 arg1Of Sp1cons,or
R9529 T11699 T11696 arg2Of or,with
R953 T1167 T1166 arg2Of induces,and
R9530 T11699 T11697 arg1Of or,the
R9531 T11701 T11699 arg2Of probes,or
R9532 T11701 T11700 arg1Of probes,APO-Sp1/3
R9533 T11703 T11702 arg1Of shifted,","
R9534 T11703 T11704 arg1Of shifted,in
R9535 T11703 T11720 arg1Of shifted,","
R9536 T11703 T11721 arg1Of shifted,whereas
R9537 T11706 T11704 arg2Of presence,in
R9538 T11706 T11705 arg1Of presence,the
R9539 T11706 T11707 arg1Of presence,of
R954 T1167 T1171 arg1Of induces,","
R9540 T11710 T11707 arg2Of antibody,of
R9541 T11710 T11708 arg1Of antibody,the
R9542 T11710 T11709 arg1Of antibody,Sp1
R9543 T11710 T11711 arg1Of antibody,(
R9544 T11713 T11711 arg2Of 6B,(
R9545 T11713 T11712 arg1Of 6B,Figure
R9546 T11713 T11714 arg1Of 6B,","
R9547 T11716 T11717 arg1Of 3,and
R9548 T11717 T11714 arg2Of and,","
R9549 T11717 T11715 arg1Of and,lanes
R955 T1167 T1172 arg1Of induces,although
R9550 T11718 T11717 arg2Of 7,and
R9551 T11719 T11711 arg3Of ),(
R9552 T11724 T11722 arg1Of complex,the
R9553 T11724 T11723 arg1Of complex,lower
R9554 T11724 T11725 arg1Of complex,shifted
R9555 T11725 T11721 arg2Of shifted,whereas
R9556 T11725 T11726 arg1Of shifted,in
R9557 T11728 T11726 arg2Of presence,in
R9558 T11728 T11727 arg1Of presence,the
R9559 T11728 T11729 arg1Of presence,of
R956 T1170 T1167 arg2Of deaminations,induces
R9560 T11732 T11729 arg2Of antibody,of
R9561 T11732 T11730 arg1Of antibody,the
R9562 T11732 T11731 arg1Of antibody,Sp3
R9563 T11732 T11733 arg1Of antibody,(
R9564 T11735 T11733 arg2Of 6B,(
R9565 T11735 T11734 arg1Of 6B,Figure
R9566 T11735 T11736 arg1Of 6B,","
R9567 T11738 T11739 arg1Of 4,and
R9568 T11739 T11736 arg2Of and,","
R9569 T11739 T11737 arg1Of and,lanes
R957 T1170 T1168 arg1Of deaminations,similar
R9570 T11740 T11739 arg2Of 8,and
R9571 T11741 T11733 arg3Of ),(
R9572 T11742 T11743 arg1Of Taken,together
R9573 T11746 T11745 arg1Of EMSA,the
R9574 T11746 T11747 arg1Of EMSA,demonstrated
R9575 T11747 T11742 modOf demonstrated,Taken
R9576 T11747 T11744 arg1Of demonstrated,","
R9577 T11750 T11749 arg1Of GC-box,the
R9578 T11750 T11751 arg1Of GC-box,located
R9579 T11750 T11757 arg1Of GC-box,serves
R958 T1170 T1169 arg1Of deaminations,C-to-U
R9580 T11751 T11752 arg1Of located,on
R9581 T11756 T11752 arg2Of promoter,on
R9582 T11756 T11753 arg1Of promoter,the
R9583 T11756 T11754 arg1Of promoter,A3G
R9584 T11756 T11755 arg1Of promoter,core
R9585 T11757 T11747 arg2Of serves,demonstrated
R9586 T11757 T11748 arg1Of serves,that
R9587 T11757 T11758 arg1Of serves,as
R9588 T11761 T11758 arg2Of site,as
R9589 T11761 T11759 arg1Of site,a
R959 T1174 T1173 arg1Of proteins,the
R9590 T11761 T11760 arg1Of site,binding
R9591 T11761 T11762 arg1Of site,for
R9592 T11763 T11764 arg1Of Sp1,and
R9593 T11764 T11762 arg2Of and,for
R9594 T11765 T11764 arg2Of Sp3,and
R9595 T11767 T11766 arg1Of show,To
R9596 T11767 T11775 arg1Of show,in
R9597 T11768 T11767 arg2Of binding,show
R9598 T11768 T11769 arg1Of binding,of
R9599 T11770 T11771 arg1Of Sp1,and
R96 T129 T126 arg2Of regulation,into
R960 T1174 T1175 arg1Of proteins,differ
R9600 T11772 T11771 arg2Of Sp3,and
R9601 T11773 T11769 arg2Of factors,of
R9602 T11773 T11770 arg1Of factors,Sp1
R9603 T11773 T11772 arg1Of factors,Sp3
R9604 T11775 T11774 arg1Of in,also
R9605 T11777 T11775 arg2Of context,in
R9606 T11777 T11776 arg1Of context,the
R9607 T11777 T11778 arg1Of context,of
R9608 T11782 T11778 arg2Of promoter,of
R9609 T11782 T11779 arg1Of promoter,the
R961 T1175 T1172 arg2Of differ,although
R9610 T11782 T11780 arg1Of promoter,endogenous
R9611 T11782 T11781 arg1Of promoter,A3G
R9612 T11788 T11787 arg2Of ChIP,(
R9613 T11789 T11787 arg3Of ),(
R9614 T11790 T11767 arg1Of assay,show
R9615 T11790 T11784 arg1Of assay,a
R9616 T11790 T11785 arg1Of assay,chromatin
R9617 T11790 T11786 arg1Of assay,immunoprecipitation
R9618 T11790 T11787 arg1Of assay,(
R9619 T11790 T11791 arg1Of assay,was
R962 T1175 T1176 arg1Of differ,in
R9620 T11790 T11792 arg2Of assay,performed
R9621 T11792 T11766 modOf performed,To
R9622 T11792 T11783 arg1Of performed,","
R9623 T11792 T11791 arg2Of performed,was
R9624 T11793 T11794 arg1Of Sp1,and
R9625 T11795 T11794 arg2Of Sp3,and
R9626 T11796 T11793 arg1Of antibodies,Sp1
R9627 T11796 T11795 arg1Of antibodies,Sp3
R9628 T11796 T11798 arg1Of antibodies,but
R9629 T11798 T11797 arg1Of but,","
R963 T1180 T1176 arg2Of specificity,in
R9630 T11798 T11799 arg1Of but,not
R9631 T11798 T11804 arg1Of but,immunoprecipitated
R9632 T11802 T11798 arg2Of antibody,but
R9633 T11802 T11800 arg1Of antibody,an
R9634 T11802 T11801 arg1Of antibody,actin
R9635 T11804 T11803 arg1Of immunoprecipitated,","
R9636 T11804 T11808 arg1Of immunoprecipitated,in
R9637 T11807 T11804 arg2Of promoter,immunoprecipitated
R9638 T11807 T11805 arg1Of promoter,the
R9639 T11807 T11806 arg1Of promoter,A3G
R964 T1180 T1177 arg1Of specificity,their
R9640 T11810 T11808 arg2Of cells,in
R9641 T11810 T11809 arg1Of cells,A3.01 T
R9642 T11810 T11811 arg1Of cells,(
R9643 T11813 T11811 arg2Of 6C,(
R9644 T11813 T11812 arg1Of 6C,Figure
R9645 T11813 T11814 arg1Of 6C,","
R9646 T11816 T11814 arg2Of panel,","
R9647 T11816 T11815 arg1Of panel,upper
R9648 T11817 T11811 arg3Of ),(
R9649 T11819 T11818 arg2Of contrast,In
R965 T1180 T1178 arg1Of specificity,target
R9650 T11823 T11821 arg1Of signal,no
R9651 T11823 T11822 arg1Of signal,PCR
R9652 T11823 T11824 arg1Of signal,was
R9653 T11823 T11825 arg2Of signal,received
R9654 T11825 T11818 arg1Of received,In
R9655 T11825 T11820 arg1Of received,","
R9656 T11825 T11824 arg2Of received,was
R9657 T11825 T11826 arg1Of received,with
R9658 T11829 T11826 arg2Of pair,with
R9659 T11829 T11827 arg1Of pair,a
R966 T1180 T1179 arg1Of specificity,sequences
R9660 T11829 T11828 arg1Of pair,primer
R9661 T11829 T11830 arg1Of pair,recognizing
R9662 T11832 T11830 arg2Of region,recognizing
R9663 T11832 T11831 arg1Of region,a
R9664 T11832 T11833 arg1Of region,in
R9665 T11837 T11833 arg2Of ∼4000 bp,in
R9666 T11837 T11834 arg1Of ∼4000 bp,the
R9667 T11837 T11835 arg1Of ∼4000 bp,A3G
R9668 T11837 T11836 arg1Of ∼4000 bp,gene
R9669 T11837 T11838 arg1Of ∼4000 bp,downstream
R967 T1180 T1181 arg1Of specificity,(
R9670 T11837 T11843 arg1Of ∼4000 bp,(
R9671 T11838 T11839 arg1Of downstream,of
R9672 T11842 T11839 arg2Of site,of
R9673 T11842 T11840 arg1Of site,the
R9674 T11842 T11841 arg1Of site,Sp1/Sp3–binding
R9675 T11845 T11844 arg1Of 6C,Figure
R9676 T11845 T11846 arg1Of 6C,","
R9677 T11846 T11843 arg2Of ",",(
R9678 T11848 T11846 arg2Of panel,","
R9679 T11848 T11847 arg1Of panel,lower
R968 T1182 T1181 arg2Of "26,28",(
R9680 T11849 T11843 arg3Of ),(
R9681 T11853 T11850 arg1Of controls,Only
R9682 T11853 T11851 arg1Of controls,the
R9683 T11853 T11852 arg1Of controls,positive
R9684 T11853 T11854 arg1Of controls,showed
R9685 T11854 T11858 arg1Of showed,","
R9686 T11854 T11859 arg1Of showed,with
R9687 T11857 T11854 arg2Of band,showed
R9688 T11857 T11855 arg1Of band,a
R9689 T11857 T11856 arg1Of band,DNA
R969 T1183 T1181 arg3Of ),(
R9690 T11863 T11860 arg1Of plasmid,an
R9691 T11863 T11861 arg1Of plasmid,A3G
R9692 T11863 T11862 arg1Of plasmid,expression
R9693 T11863 T11864 arg1Of plasmid,or
R9694 T11864 T11859 arg2Of or,with
R9695 T11866 T11867 arg1Of sheared,and
R9696 T11868 T11867 arg2Of cross-linked,and
R9697 T11870 T11864 arg2Of DNA,or
R9698 T11870 T11865 arg1Of DNA,the
R9699 T11870 T11866 arg1Of DNA,sheared
R97 T129 T127 arg1Of regulation,the
R970 T1187 T1186 arg1Of proteins,A3F
R9700 T11870 T11868 arg1Of DNA,cross-linked
R9701 T11870 T11869 arg1Of DNA,input
R9702 T11870 T11871 arg2Of DNA,used
R9703 T11871 T11872 arg1Of used,as
R9704 T11873 T11872 arg2Of template,as
R9705 T11874 T11875 arg1Of This,demonstrates
R9706 T11877 T11875 arg2Of binding,demonstrates
R9707 T11877 T11876 arg1Of binding,the
R9708 T11877 T11878 arg1Of binding,of
R9709 T11877 T11884 arg1Of binding,to
R971 T1187 T1188 arg1Of proteins,were
R9710 T11879 T11880 arg1Of Sp1,and
R9711 T11881 T11880 arg2Of Sp3,and
R9712 T11883 T11878 arg2Of factors,of
R9713 T11883 T11879 arg1Of factors,Sp1
R9714 T11883 T11881 arg1Of factors,Sp3
R9715 T11883 T11882 arg1Of factors,transcription
R9716 T11888 T11884 arg2Of promoter,to
R9717 T11888 T11885 arg1Of promoter,the
R9718 T11888 T11886 arg1Of promoter,endogenous
R9719 T11888 T11887 arg1Of promoter,A3G
R972 T1187 T1189 arg2Of proteins,detected
R973 T1189 T1184 arg1Of detected,Furthermore
R974 T1189 T1185 arg1Of detected,","
R975 T1189 T1188 arg2Of detected,were
R976 T1189 T1190 arg1Of detected,in
R977 T1192 T1190 arg2Of tissues,in
R978 T1192 T1191 arg1Of tissues,many
R979 T1192 T1193 arg1Of tissues,that
R98 T129 T128 arg1Of regulation,transcriptional
R980 T1192 T1194 arg1Of tissues,express
R981 T1192 T1197 arg1Of tissues,are
R982 T1192 T1198 arg1Of tissues,able
R983 T1192 T1200 arg1Of tissues,form
R984 T1194 T1196 arg1Of express,and
R985 T1195 T1194 arg2Of A3G,express
R986 T1197 T1196 arg2Of are,and
R987 T1198 T1197 arg2Of able,are
R988 T1200 T1198 arg2Of form,able
R989 T1200 T1199 arg1Of form,to
R99 T129 T130 arg1Of regulation,of
R990 T1200 T1202 arg1Of form,with
R991 T1201 T1200 arg2Of heteromultimers,form
R992 T1203 T1202 arg2Of A3G,with
R993 T1203 T1204 arg1Of A3G,(
R994 T1205 T1204 arg2Of "26,29,30",(
R995 T1206 T1204 arg3Of ),(
R996 T1208 T1207 arg1Of proteins,Both
R997 T1208 T1209 arg1Of proteins,localize
R998 T1209 T1210 arg1Of localize,to
R999 T1212 T1210 arg2Of processing,to