| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T30 |
600-603 |
Gene |
denotes |
p53 |
| T10 |
651-685 |
Var |
denotes |
mutations on the Arg248 and Arg282 |
| T29 |
735-742 |
NegReg |
denotes |
shorter |
| T12 |
743-759 |
CPA |
denotes |
patient survival |
| T21 |
869-878 |
Var |
denotes |
mutations |
| T13 |
888-894 |
PosReg |
denotes |
higher |
| T14 |
895-903 |
MPA |
denotes |
activity |
| T32 |
907-932 |
Enzyme |
denotes |
drug-metabolizing enzymes |
| T33 |
948-970 |
Enzyme |
denotes |
CYP3A4 cytochrome P450 |
| T22 |
972-990 |
MPA |
denotes |
Ectopic expression |
| T23 |
994-997 |
Gene |
denotes |
p53 |
| T24 |
998-1010 |
Var |
denotes |
mutant R282W |
| T16 |
1050-1061 |
PosReg |
denotes |
upregulated |
| T17 |
1062-1092 |
MPA |
denotes |
CYP3A4 mRNA and protein levels |
| T25 |
1145-1148 |
Gene |
denotes |
p53 |
| T26 |
1149-1158 |
Var |
denotes |
mutations |
| T18 |
1167-1173 |
PosReg |
denotes |
higher |
| T31 |
1174-1180 |
Enzyme |
denotes |
CYP3A4 |
| T19 |
1181-1191 |
MPA |
denotes |
expression |
| T20 |
1196-1259 |
CPA |
denotes |
resistance to several CYP3A4-metabolized chemotherapeutic drugs |
| R10 |
T21 |
T13 |
CauseOf |
mutations,higher |
| R11 |
T14 |
T13 |
ThemeOf |
activity,higher |
| R12 |
T23 |
T24 |
ThemeOf |
p53,mutant R282W |
| R13 |
T24 |
T22 |
ThemeOf |
mutant R282W,Ectopic expression |
| R14 |
T22 |
T16 |
CauseOf |
Ectopic expression,upregulated |
| R15 |
T17 |
T16 |
ThemeOf |
CYP3A4 mRNA and protein levels,upregulated |
| R16 |
T19 |
T18 |
ThemeOf |
expression,higher |
| R17 |
T20 |
T18 |
ThemeOf |
resistance to several CYP3A4-metabolized chemotherapeutic drugs,higher |
| R18 |
T25 |
T26 |
ThemeOf |
p53,mutations |
| R19 |
T26 |
T18 |
CauseOf |
mutations,higher |
| R22 |
T10 |
T29 |
CauseOf |
mutations on the Arg248 and Arg282,shorter |
| R23 |
T12 |
T29 |
ThemeOf |
patient survival,shorter |
| R24 |
T30 |
T10 |
ThemeOf |
p53,mutations on the Arg248 and Arg282 |
| R25 |
T32 |
T14 |
ThemeOf |
drug-metabolizing enzymes,activity |
| R26 |
T33 |
T32 |
ThemeOf |
CYP3A4 cytochrome P450,drug-metabolizing enzymes |
| R27 |
T31 |
T19 |
ThemeOf |
CYP3A4,expression |