PubMed:32234468 JSONTXT 10 Projects

The epidemiology, diagnosis and treatment of COVID-19. In December 2019, the outbreak of the 2019 novel coronavirus disease (COVID-19) in China spread worldwide, becoming an emergency of major international concern. SARS-CoV-2 infection causes clusters of severe respiratory illness similar to severe acute respiratory syndrome coronavirus. Human-to-human transmission has been described with incubation times between 2-14 days, facilitating its spread via droplets, contaminated hands or surfaces. Early diagnosis, quarantine, and supportive treatments are essential to cure patients. We therefore reviewed the literature on all available information about the epidemiology, diagnosis, isolation and treatments of COVID-19. Treatments, including antiviral agents, chloroquine and hydroxychloroquine, corticosteroids, antibodies, convalescent plasma transfusion and vaccines, will be discussed in this article. Additionally, registered trials about treatment were listed to develop approaches for the current urgent demand for therapy.