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PMC:539061 / 9261-10362 JSONTXT 4 Projects

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Id Subject Object Predicate Lexical cue
T2857 0-3 NN denotes PCR
T2858 4-12 NNS denotes analyses
T2859 13-23 VBD denotes identified
T2860 24-33 JJ denotes transient
T2862 34-39 NN denotes Snail
T2863 40-44 NN denotes mRNA
T2861 45-55 NN denotes expression
T2864 56-62 IN denotes during
T2865 63-64 DT denotes a
T2866 65-71 NN denotes period
T2867 72-74 IN denotes of
T2868 75-79 NN denotes skin
T2869 80-93 NN denotes embryogenesis
T2870 94-98 WRB denotes when
T2872 99-104 NNS denotes waves
T2873 105-107 IN denotes of
T2874 108-112 NN denotes hair
T2875 113-122 NNS denotes follicles
T2876 123-126 VBP denotes are
T2871 127-134 VBG denotes forming
T2877 135-136 -LRB- denotes (
T2879 136-147 JJ denotes unpublished
T2878 148-152 NNS denotes data
T2880 152-153 -RRB- denotes )
T2881 153-154 . denotes .
T2882 154-156 TO denotes To
T2884 154-336 sentence denotes To pinpoint specifically where Snail mRNA is expressed in the developing skin, we conducted in situ hybridization using a cRNA probe unique to the Snail 3′ untranslated region (UTR).
T2883 157-165 VB denotes pinpoint
T2886 166-178 RB denotes specifically
T2887 179-184 WRB denotes where
T2889 185-190 NN denotes Snail
T2890 191-195 NN denotes mRNA
T2891 196-198 VBZ denotes is
T2888 199-208 VBN denotes expressed
T2892 209-211 IN denotes in
T2893 212-215 DT denotes the
T2895 216-226 VBG denotes developing
T2894 227-231 NN denotes skin
T2896 231-233 , denotes ,
T2897 233-235 PRP denotes we
T2885 236-245 VBD denotes conducted
T2898 246-248 FW denotes in
T2899 249-253 FW denotes situ
T2900 254-267 NN denotes hybridization
T2901 268-273 VBG denotes using
T2902 274-275 DT denotes a
T2904 276-280 NN denotes cRNA
T2903 281-286 NN denotes probe
T2905 287-293 JJ denotes unique
T2906 294-296 IN denotes to
T2907 297-300 DT denotes the
T2909 301-306 NNP denotes Snail
T2910 307-308 CD denotes 3
T2911 308-309 SYM denotes ′
T2912 310-322 JJ denotes untranslated
T2908 323-329 NN denotes region
T2913 330-331 -LRB- denotes (
T2914 331-334 NN denotes UTR
T2915 334-335 -RRB- denotes )
T2916 335-336 . denotes .
T2917 336-525 sentence denotes Embryonic day 17.5 (E17.5) was chosen, since the multiple waves of follicle morphogenesis occurring at this time enabled us to evaluate Snail expression at different stages of the process.
T2918 337-346 JJ denotes Embryonic
T2919 347-350 NN denotes day
T2921 351-355 CD denotes 17.5
T2922 356-357 -LRB- denotes (
T2923 357-362 NN denotes E17.5
T2924 362-363 -RRB- denotes )
T2925 364-367 VBD denotes was
T2920 368-374 VBN denotes chosen
T2926 374-376 , denotes ,
T2927 376-381 IN denotes since
T2929 382-385 DT denotes the
T2931 386-394 JJ denotes multiple
T2930 395-400 NNS denotes waves
T2932 401-403 IN denotes of
T2933 404-412 NN denotes follicle
T2934 413-426 NN denotes morphogenesis
T2935 427-436 VBG denotes occurring
T2936 437-439 IN denotes at
T2937 440-444 DT denotes this
T2938 445-449 NN denotes time
T2928 450-457 VBD denotes enabled
T2939 458-460 PRP denotes us
T2940 461-463 TO denotes to
T2941 464-472 VB denotes evaluate
T2942 473-478 NN denotes Snail
T2943 479-489 NN denotes expression
T2944 490-492 IN denotes at
T2945 493-502 JJ denotes different
T2946 503-509 NNS denotes stages
T2947 510-512 IN denotes of
T2948 513-516 DT denotes the
T2949 517-524 NN denotes process
T2950 524-525 . denotes .
T2951 525-628 sentence denotes As shown in Figure 1A, specific hybridization was detected within the epithelium of nascent hair buds.
T2952 526-528 IN denotes As
T2953 529-534 VBN denotes shown
T2955 535-537 IN denotes in
T2956 538-544 NN denotes Figure
T2957 545-547 NN denotes 1A
T2958 547-549 , denotes ,
T2959 549-557 JJ denotes specific
T2960 558-571 NN denotes hybridization
T2961 572-575 VBD denotes was
T2954 576-584 VBN denotes detected
T2962 585-591 IN denotes within
T2963 592-595 DT denotes the
T2964 596-606 NN denotes epithelium
T2965 607-609 IN denotes of
T2966 610-617 JJ denotes nascent
T2968 618-622 NN denotes hair
T2967 623-627 NNS denotes buds
T2969 627-628 . denotes .
T2970 628-782 sentence denotes By contrast, as follicles progressed further through their development (e.g., germ and peg stages), they exhibited no signs of hybridization (Figure 1A).
T2971 629-631 IN denotes By
T2973 632-640 NN denotes contrast
T2974 640-642 , denotes ,
T2975 642-644 IN denotes as
T2977 645-654 NNS denotes follicles
T2976 655-665 VBD denotes progressed
T2978 666-673 RBR denotes further
T2979 674-681 IN denotes through
T2980 682-687 PRP$ denotes their
T2981 688-699 NN denotes development
T2982 700-701 -LRB- denotes (
T2984 701-705 FW denotes e.g.
T2985 705-707 , denotes ,
T2986 707-711 NN denotes germ
T2987 712-715 CC denotes and
T2988 716-719 NN denotes peg
T2983 720-726 NNS denotes stages
T2989 726-727 -RRB- denotes )
T2990 727-729 , denotes ,
T2991 729-733 PRP denotes they
T2972 734-743 VBD denotes exhibited
T2992 744-746 DT denotes no
T2993 747-752 NNS denotes signs
T2994 753-755 IN denotes of
T2995 756-769 NN denotes hybridization
T2996 770-771 -LRB- denotes (
T2998 771-777 NN denotes Figure
T2997 778-780 NN denotes 1A
T2999 780-781 -RRB- denotes )
T3000 781-782 . denotes .
T3001 782-989 sentence denotes The transient nature of Snail mRNA expression during follicle development was most apparent in hybridized skin sections containing follicles from two different waves of morphogenesis (as shown in Figure 1).
T3002 783-786 DT denotes The
T3004 787-796 JJ denotes transient
T3003 797-803 NN denotes nature
T3006 804-806 IN denotes of
T3007 807-812 NN denotes Snail
T3009 813-817 NN denotes mRNA
T3008 818-828 NN denotes expression
T3010 829-835 IN denotes during
T3011 836-844 NN denotes follicle
T3012 845-856 NN denotes development
T3005 857-860 VBD denotes was
T3013 861-865 RBS denotes most
T3014 866-874 JJ denotes apparent
T3015 875-877 IN denotes in
T3016 878-888 VBN denotes hybridized
T3018 889-893 NN denotes skin
T3017 894-902 NNS denotes sections
T3019 903-913 VBG denotes containing
T3020 914-923 NNS denotes follicles
T3021 924-928 IN denotes from
T3022 929-932 CD denotes two
T3024 933-942 JJ denotes different
T3023 943-948 NNS denotes waves
T3025 949-951 IN denotes of
T3026 952-965 NN denotes morphogenesis
T3027 966-967 -LRB- denotes (
T3029 967-969 IN denotes as
T3028 970-975 VBN denotes shown
T3030 976-978 IN denotes in
T3031 979-985 NN denotes Figure
T3032 986-987 CD denotes 1
T3033 987-988 -RRB- denotes )
T3034 988-989 . denotes .
T3035 989-1101 sentence denotes Hybridizing hair buds from a later wave appeared juxtaposed with nonhybridizing follicles from an earlier wave.
T3036 990-1001 VBG denotes Hybridizing
T3038 1002-1006 NN denotes hair
T3037 1007-1011 NNS denotes buds
T3040 1012-1016 IN denotes from
T3041 1017-1018 DT denotes a
T3043 1019-1024 JJ denotes later
T3042 1025-1029 NN denotes wave
T3039 1030-1038 VBD denotes appeared
T3044 1039-1049 JJ denotes juxtaposed
T3045 1050-1054 IN denotes with
T3046 1055-1069 JJ denotes nonhybridizing
T3047 1070-1079 NNS denotes follicles
T3048 1080-1084 IN denotes from
T3049 1085-1087 DT denotes an
T3051 1088-1095 JJR denotes earlier
T3050 1096-1100 NN denotes wave
T3052 1100-1101 . denotes .
R1580 T2857 T2858 compound PCR,analyses
R1581 T2858 T2859 nsubj analyses,identified
R1582 T2860 T2861 amod transient,expression
R1583 T2861 T2859 dobj expression,identified
R1584 T2862 T2861 compound Snail,expression
R1585 T2863 T2861 compound mRNA,expression
R1586 T2864 T2859 prep during,identified
R1587 T2865 T2866 det a,period
R1588 T2866 T2864 pobj period,during
R1589 T2867 T2866 prep of,period
R1590 T2868 T2869 compound skin,embryogenesis
R1591 T2869 T2867 pobj embryogenesis,of
R1592 T2870 T2871 advmod when,forming
R1593 T2871 T2866 advcl forming,period
R1594 T2872 T2871 nsubj waves,forming
R1595 T2873 T2872 prep of,waves
R1596 T2874 T2875 compound hair,follicles
R1597 T2875 T2873 pobj follicles,of
R1598 T2876 T2871 aux are,forming
R1599 T2877 T2878 punct (,data
R1600 T2878 T2859 meta data,identified
R1601 T2879 T2878 amod unpublished,data
R1602 T2880 T2878 punct ),data
R1603 T2881 T2859 punct .,identified
R1604 T2882 T2883 aux To,pinpoint
R1605 T2883 T2885 advcl pinpoint,conducted
R1606 T2886 T2883 advmod specifically,pinpoint
R1607 T2887 T2888 advmod where,expressed
R1608 T2888 T2883 advcl expressed,pinpoint
R1609 T2889 T2890 compound Snail,mRNA
R1610 T2890 T2888 nsubjpass mRNA,expressed
R1611 T2891 T2888 auxpass is,expressed
R1612 T2892 T2888 prep in,expressed
R1613 T2893 T2894 det the,skin
R1614 T2894 T2892 pobj skin,in
R1615 T2895 T2894 amod developing,skin
R1616 T2896 T2885 punct ", ",conducted
R1617 T2897 T2885 nsubj we,conducted
R1618 T2898 T2899 advmod in,situ
R1619 T2899 T2900 amod situ,hybridization
R1620 T2900 T2885 dobj hybridization,conducted
R1621 T2901 T2885 advcl using,conducted
R1622 T2902 T2903 det a,probe
R1623 T2903 T2901 dobj probe,using
R1624 T2904 T2903 compound cRNA,probe
R1625 T2905 T2903 amod unique,probe
R1626 T2906 T2905 prep to,unique
R1627 T2907 T2908 det the,region
R1628 T2908 T2906 pobj region,to
R1629 T2909 T2908 nmod Snail,region
R1630 T2910 T2908 nummod 3,region
R1631 T2911 T2910 punct ′,3
R1632 T2912 T2908 amod untranslated,region
R1633 T2913 T2908 punct (,region
R1634 T2914 T2908 appos UTR,region
R1635 T2915 T2908 punct ),region
R1636 T2916 T2885 punct .,conducted
R1637 T2918 T2919 amod Embryonic,day
R1638 T2919 T2920 nsubjpass day,chosen
R1639 T2921 T2919 nummod 17.5,day
R1640 T2922 T2919 punct (,day
R1641 T2923 T2919 appos E17.5,day
R1642 T2924 T2920 punct ),chosen
R1643 T2925 T2920 auxpass was,chosen
R1644 T2926 T2920 punct ", ",chosen
R1645 T2927 T2928 mark since,enabled
R1646 T2928 T2920 advcl enabled,chosen
R1647 T2929 T2930 det the,waves
R1648 T2930 T2928 nsubj waves,enabled
R1649 T2931 T2930 amod multiple,waves
R1650 T2932 T2930 prep of,waves
R1651 T2933 T2934 compound follicle,morphogenesis
R1652 T2934 T2932 pobj morphogenesis,of
R1653 T2935 T2930 acl occurring,waves
R1654 T2936 T2935 prep at,occurring
R1655 T2937 T2938 det this,time
R1656 T2938 T2936 pobj time,at
R1657 T2939 T2928 dobj us,enabled
R1658 T2940 T2941 aux to,evaluate
R1659 T2941 T2928 xcomp evaluate,enabled
R1660 T2942 T2943 compound Snail,expression
R1661 T2943 T2941 dobj expression,evaluate
R1662 T2944 T2941 prep at,evaluate
R1663 T2945 T2946 amod different,stages
R1664 T2946 T2944 pobj stages,at
R1665 T2947 T2946 prep of,stages
R1666 T2948 T2949 det the,process
R1667 T2949 T2947 pobj process,of
R1668 T2950 T2920 punct .,chosen
R1669 T2952 T2953 mark As,shown
R1670 T2953 T2954 advcl shown,detected
R1671 T2955 T2953 prep in,shown
R1672 T2956 T2957 compound Figure,1A
R1673 T2957 T2955 pobj 1A,in
R1674 T2958 T2954 punct ", ",detected
R1675 T2959 T2960 amod specific,hybridization
R1676 T2960 T2954 nsubjpass hybridization,detected
R1677 T2961 T2954 auxpass was,detected
R1678 T2962 T2954 prep within,detected
R1679 T2963 T2964 det the,epithelium
R1680 T2964 T2962 pobj epithelium,within
R1681 T2965 T2964 prep of,epithelium
R1682 T2966 T2967 amod nascent,buds
R1683 T2967 T2965 pobj buds,of
R1684 T2968 T2967 compound hair,buds
R1685 T2969 T2954 punct .,detected
R1686 T2971 T2972 prep By,exhibited
R1687 T2973 T2971 pobj contrast,By
R1688 T2974 T2972 punct ", ",exhibited
R1689 T2975 T2976 mark as,progressed
R1690 T2976 T2972 advcl progressed,exhibited
R1691 T2977 T2976 nsubj follicles,progressed
R1692 T2978 T2976 advmod further,progressed
R1693 T2979 T2976 prep through,progressed
R1694 T2980 T2981 poss their,development
R1695 T2981 T2979 pobj development,through
R1696 T2982 T2983 punct (,stages
R1697 T2983 T2976 parataxis stages,progressed
R1698 T2984 T2983 advmod e.g.,stages
R1699 T2985 T2983 punct ", ",stages
R1700 T2986 T2983 nmod germ,stages
R1701 T2987 T2986 cc and,germ
R1702 T2988 T2986 conj peg,germ
R1703 T2989 T2983 punct ),stages
R1704 T2990 T2972 punct ", ",exhibited
R1705 T2991 T2972 nsubj they,exhibited
R1706 T2992 T2993 det no,signs
R1707 T2993 T2972 dobj signs,exhibited
R1708 T2994 T2993 prep of,signs
R1709 T2995 T2994 pobj hybridization,of
R1710 T2996 T2997 punct (,1A
R1711 T2997 T2972 parataxis 1A,exhibited
R1712 T2998 T2997 compound Figure,1A
R1713 T2999 T2997 punct ),1A
R1714 T3000 T2972 punct .,exhibited
R1715 T3002 T3003 det The,nature
R1716 T3003 T3005 nsubj nature,was
R1717 T3004 T3003 amod transient,nature
R1718 T3006 T3003 prep of,nature
R1719 T3007 T3008 compound Snail,expression
R1720 T3008 T3006 pobj expression,of
R1721 T3009 T3008 compound mRNA,expression
R1722 T3010 T3008 prep during,expression
R1723 T3011 T3012 compound follicle,development
R1724 T3012 T3010 pobj development,during
R1725 T3013 T3014 advmod most,apparent
R1726 T3014 T3005 acomp apparent,was
R1727 T3015 T3005 prep in,was
R1728 T3016 T3017 amod hybridized,sections
R1729 T3017 T3015 pobj sections,in
R1730 T3018 T3017 compound skin,sections
R1731 T3019 T3017 acl containing,sections
R1732 T3020 T3019 dobj follicles,containing
R1733 T3021 T3020 prep from,follicles
R1734 T3022 T3023 nummod two,waves
R1735 T3023 T3021 pobj waves,from
R1736 T3024 T3023 amod different,waves
R1737 T3025 T3023 prep of,waves
R1738 T3026 T3025 pobj morphogenesis,of
R1739 T3027 T3028 punct (,shown
R1740 T3028 T3005 parataxis shown,was
R1741 T3029 T3028 mark as,shown
R1742 T3030 T3028 prep in,shown
R1743 T3031 T3030 pobj Figure,in
R1744 T3032 T3031 nummod 1,Figure
R1745 T3033 T3028 punct ),shown
R1746 T3034 T3005 punct .,was
R1747 T3036 T3037 amod Hybridizing,buds
R1748 T3037 T3039 nsubj buds,appeared
R1749 T3038 T3037 compound hair,buds
R1750 T3040 T3037 prep from,buds
R1751 T3041 T3042 det a,wave
R1752 T3042 T3040 pobj wave,from
R1753 T3043 T3042 amod later,wave
R1754 T3044 T3039 oprd juxtaposed,appeared
R1755 T3045 T3044 prep with,juxtaposed
R1756 T3046 T3047 amod nonhybridizing,follicles
R1757 T3047 T3045 pobj follicles,with
R1758 T3048 T3047 prep from,follicles
R1759 T3049 T3050 det an,wave
R1760 T3050 T3048 pobj wave,from
R1761 T3051 T3050 amod earlier,wave
R1762 T3052 T3039 punct .,appeared