craft-sa-dev Home  

PMC:539061 / 43483-44245 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T8659 0-8 IN denotes Although
T8661 9-13 DT denotes some
T8663 14-18 NN denotes hair
T8662 19-23 NNS denotes buds
T8664 24-29 RB denotes still
T8660 30-36 VBD denotes formed
T8666 37-39 IN denotes in
T8667 40-43 NN denotes TGF
T8669 43-44 HYPH denotes -
T8668 44-46 NN denotes β2
T8670 47-51 JJ denotes null
T8671 52-56 NN denotes skin
T8672 56-58 , denotes ,
T8673 58-63 PRP$ denotes their
T8674 64-70 NN denotes number
T8675 71-74 VBD denotes was
T8665 75-82 VBN denotes reduced
T8676 83-85 IN denotes by
T8677 86-99 RB denotes approximately
T8678 100-102 CD denotes 50
T8679 102-103 NN denotes %
T8680 104-105 -LRB- denotes [
T8681 105-107 CD denotes 32
T8682 107-108 -RRB- denotes ]
T8683 108-109 . denotes .
T8684 109-277 sentence denotes Thus, although the pathway mediated by TGF-β2 signaling impacts the earliest step of epithelial invagination, it does not appear to be essential for bud morphogenesis.
T8685 110-114 RB denotes Thus
T8687 114-116 , denotes ,
T8688 116-124 IN denotes although
T8690 125-128 DT denotes the
T8691 129-136 NN denotes pathway
T8692 137-145 VBN denotes mediated
T8693 146-148 IN denotes by
T8694 149-152 NN denotes TGF
T8696 152-153 HYPH denotes -
T8695 153-155 NN denotes β2
T8697 156-165 NN denotes signaling
T8689 166-173 VBZ denotes impacts
T8698 174-177 DT denotes the
T8700 178-186 JJS denotes earliest
T8699 187-191 NN denotes step
T8701 192-194 IN denotes of
T8702 195-205 JJ denotes epithelial
T8703 206-218 NN denotes invagination
T8704 218-220 , denotes ,
T8705 220-222 PRP denotes it
T8706 223-227 VBZ denotes does
T8707 228-231 RB denotes not
T8686 232-238 VB denotes appear
T8708 239-241 TO denotes to
T8709 242-244 VB denotes be
T8710 245-254 JJ denotes essential
T8711 255-258 IN denotes for
T8712 259-262 NN denotes bud
T8713 263-276 NN denotes morphogenesis
T8714 276-277 . denotes .
T8715 277-551 sentence denotes Consistent with this notion, basement membrane remodeling still took place in the TGF-β2-null buds, as judged by immunofluorescence with antibodies against β4 integrin, an integral component of keratinocyte-mediated adhesion to its underlying basement membrane (Figure 6F).
T8716 278-288 JJ denotes Consistent
T8718 289-293 IN denotes with
T8719 294-298 DT denotes this
T8720 299-305 NN denotes notion
T8721 305-307 , denotes ,
T8722 307-315 NN denotes basement
T8723 316-324 NN denotes membrane
T8724 325-335 NN denotes remodeling
T8725 336-341 RB denotes still
T8717 342-346 VBD denotes took
T8726 347-352 RP denotes place
T8727 353-355 IN denotes in
T8728 356-359 DT denotes the
T8730 360-363 NN denotes TGF
T8732 363-364 HYPH denotes -
T8731 364-366 NN denotes β2
T8734 366-367 HYPH denotes -
T8733 367-371 JJ denotes null
T8729 372-376 NNS denotes buds
T8735 376-378 , denotes ,
T8736 378-380 IN denotes as
T8737 381-387 VBN denotes judged
T8738 388-390 IN denotes by
T8739 391-409 NN denotes immunofluorescence
T8740 410-414 IN denotes with
T8741 415-425 NNS denotes antibodies
T8742 426-433 IN denotes against
T8743 434-436 NN denotes β4
T8744 437-445 NN denotes integrin
T8745 445-447 , denotes ,
T8746 447-449 DT denotes an
T8748 450-458 JJ denotes integral
T8747 459-468 NN denotes component
T8749 469-471 IN denotes of
T8750 472-484 NN denotes keratinocyte
T8752 484-485 HYPH denotes -
T8751 485-493 VBN denotes mediated
T8753 494-502 NN denotes adhesion
T8754 503-505 IN denotes to
T8755 506-509 PRP$ denotes its
T8757 510-520 JJ denotes underlying
T8758 521-529 NN denotes basement
T8756 530-538 NN denotes membrane
T8759 539-540 -LRB- denotes (
T8761 540-546 NN denotes Figure
T8760 547-549 NN denotes 6F
T8762 549-550 -RRB- denotes )
T8763 550-551 . denotes .
T8764 551-762 sentence denotes In contrast, TGF-β2 signaling appeared to be an important factor for the early proliferation that occurs in the developing hair buds, as judged by anti-Ki67 and anti-pMAPK immunofluorescence (Figure 6F and 6G).
T8765 552-554 IN denotes In
T8767 555-563 NN denotes contrast
T8768 563-565 , denotes ,
T8769 565-568 NN denotes TGF
T8771 568-569 HYPH denotes -
T8770 569-571 NN denotes β2
T8772 572-581 NN denotes signaling
T8766 582-590 VBD denotes appeared
T8773 591-593 TO denotes to
T8774 594-596 VB denotes be
T8775 597-599 DT denotes an
T8777 600-609 JJ denotes important
T8776 610-616 NN denotes factor
T8778 617-620 IN denotes for
T8779 621-624 DT denotes the
T8781 625-630 JJ denotes early
T8780 631-644 NN denotes proliferation
T8782 645-649 WDT denotes that
T8783 650-656 VBZ denotes occurs
T8784 657-659 IN denotes in
T8785 660-663 DT denotes the
T8787 664-674 VBG denotes developing
T8788 675-679 NN denotes hair
T8786 680-684 NNS denotes buds
T8789 684-686 , denotes ,
T8790 686-688 IN denotes as
T8791 689-695 VBN denotes judged
T8792 696-698 IN denotes by
T8793 699-708 JJ denotes anti-Ki67
T8795 709-712 CC denotes and
T8796 713-723 JJ denotes anti-pMAPK
T8794 724-742 NN denotes immunofluorescence
T8797 743-744 -LRB- denotes (
T8799 744-750 NN denotes Figure
T8798 751-753 NN denotes 6F
T8800 754-757 CC denotes and
T8801 758-760 NN denotes 6G
T8802 760-761 -RRB- denotes )
T8803 761-762 . denotes .
R5347 T8664 T8660 advmod still,formed
R5356 T8666 T8660 prep in,formed
R5362 T8667 T8668 compound TGF,β2
R5366 T8668 T8670 npadvmod β2,null
R5369 T8669 T8668 punct -,β2
R5373 T8670 T8671 amod null,skin
R5377 T8671 T8666 pobj skin,in
R5380 T8672 T8665 punct ", ",reduced
R5384 T8673 T8674 poss their,number
R5388 T8674 T8665 nsubjpass number,reduced
R5391 T8675 T8665 auxpass was,reduced
R5394 T8676 T8665 prep by,reduced
R5398 T8677 T8678 advmod approximately,50
R5404 T8678 T8679 nummod 50,%
R5408 T8679 T8676 pobj %,by
R5412 T8680 T8681 punct [,32
R5415 T8681 T8665 parataxis 32,reduced
R5416 T8659 T8660 mark Although,formed
R5417 T8660 T8665 advcl formed,reduced
R5418 T8661 T8662 det some,buds
R5419 T8682 T8681 punct ],32
R5420 T8662 T8660 nsubj buds,formed
R5421 T8663 T8662 compound hair,buds
R5422 T8683 T8665 punct .,reduced
R5423 T8685 T8686 advmod Thus,appear
R5424 T8687 T8686 punct ", ",appear
R5425 T8770 T8772 compound β2,signaling
R5426 T8688 T8689 mark although,impacts
R5427 T8689 T8686 advcl impacts,appear
R5428 T8771 T8770 punct -,β2
R5429 T8772 T8766 nsubj signaling,appeared
R5430 T8690 T8691 det the,pathway
R5431 T8773 T8774 aux to,be
R5432 T8774 T8766 xcomp be,appeared
R5433 T8775 T8776 det an,factor
R5434 T8691 T8689 nsubj pathway,impacts
R5435 T8776 T8774 attr factor,be
R5436 T8777 T8776 amod important,factor
R5437 T8692 T8691 acl mediated,pathway
R5438 T8778 T8776 prep for,factor
R5439 T8779 T8780 det the,proliferation
R5440 T8693 T8692 prep by,mediated
R5441 T8780 T8778 pobj proliferation,for
R5442 T8781 T8780 amod early,proliferation
R5443 T8782 T8783 dep that,occurs
R5444 T8694 T8695 compound TGF,β2
R5445 T8783 T8780 relcl occurs,proliferation
R5446 T8784 T8783 prep in,occurs
R5447 T8695 T8697 compound β2,signaling
R5448 T8785 T8786 det the,buds
R5449 T8786 T8784 pobj buds,in
R5450 T8787 T8786 amod developing,buds
R5451 T8696 T8695 punct -,β2
R5452 T8788 T8786 compound hair,buds
R5453 T8789 T8774 punct ", ",be
R5454 T8790 T8791 mark as,judged
R5455 T8791 T8774 advcl judged,be
R5456 T8792 T8791 prep by,judged
R5457 T8793 T8794 amod anti-Ki67,immunofluorescence
R5458 T8697 T8693 pobj signaling,by
R5459 T8794 T8792 pobj immunofluorescence,by
R5460 T8795 T8793 cc and,anti-Ki67
R5461 T8698 T8699 det the,step
R5462 T8796 T8793 conj anti-pMAPK,anti-Ki67
R5463 T8797 T8798 punct (,6F
R5464 T8798 T8774 parataxis 6F,be
R5465 T8699 T8689 dobj step,impacts
R5466 T8799 T8798 compound Figure,6F
R5467 T8800 T8798 cc and,6F
R5468 T8801 T8798 conj 6G,6F
R5469 T8700 T8699 amod earliest,step
R5470 T8802 T8798 punct ),6F
R5471 T8803 T8766 punct .,appeared
R5472 T8701 T8699 prep of,step
R5475 T8702 T8703 amod epithelial,invagination
R5479 T8703 T8701 pobj invagination,of
R5482 T8704 T8686 punct ", ",appear
R5486 T8705 T8686 nsubj it,appear
R5490 T8706 T8686 aux does,appear
R5493 T8707 T8686 neg not,appear
R5497 T8708 T8709 aux to,be
R5501 T8709 T8686 xcomp be,appear
R5508 T8710 T8709 acomp essential,be
R5512 T8711 T8710 prep for,essential
R5513 T8712 T8713 compound bud,morphogenesis
R5515 T8713 T8711 pobj morphogenesis,for
R5518 T8714 T8686 punct .,appear
R5523 T8716 T8717 advcl Consistent,took
R5527 T8718 T8716 prep with,Consistent
R5531 T8719 T8720 det this,notion
R5532 T8720 T8718 pobj notion,with
R5533 T8721 T8717 punct ", ",took
R5535 T8722 T8723 compound basement,membrane
R5536 T8723 T8724 compound membrane,remodeling
R5540 T8724 T8717 nsubj remodeling,took
R5543 T8725 T8717 advmod still,took
R5547 T8726 T8717 dobj place,took
R5550 T8727 T8717 prep in,took
R5554 T8728 T8729 det the,buds
R5561 T8729 T8727 pobj buds,in
R5565 T8730 T8731 compound TGF,β2
R5567 T8731 T8733 npadvmod β2,null
R5568 T8732 T8731 punct -,β2
R5569 T8733 T8729 amod null,buds
R5570 T8734 T8733 punct -,null
R5572 T8735 T8717 punct ", ",took
R5574 T8736 T8737 mark as,judged
R5578 T8737 T8717 advcl judged,took
R5582 T8738 T8737 prep by,judged
R5586 T8739 T8738 pobj immunofluorescence,by
R5589 T8740 T8739 prep with,immunofluorescence
R5593 T8741 T8740 pobj antibodies,with
R5597 T8742 T8741 prep against,antibodies
R5601 T8743 T8744 compound β4,integrin
R5603 T8744 T8742 pobj integrin,against
R5606 T8745 T8744 punct ", ",integrin
R5612 T8746 T8747 det an,component
R5616 T8747 T8744 appos component,integrin
R5620 T8748 T8747 amod integral,component
R5623 T8749 T8747 prep of,component
R5624 T8750 T8751 npadvmod keratinocyte,mediated
R5627 T8751 T8753 amod mediated,adhesion
R5631 T8752 T8751 punct -,mediated
R5635 T8753 T8749 pobj adhesion,of
R5639 T8754 T8753 prep to,adhesion
R5642 T8755 T8756 poss its,membrane
R5646 T8756 T8754 pobj membrane,to
R5649 T8757 T8756 amod underlying,membrane
R5653 T8758 T8756 compound basement,membrane
R5656 T8759 T8760 punct (,6F
R5661 T8760 T8717 parataxis 6F,took
R5665 T8761 T8760 compound Figure,6F
R5668 T8762 T8760 punct ),6F
R5672 T8763 T8717 punct .,took
R5675 T8765 T8766 prep In,appeared
R5681 T8767 T8765 pobj contrast,In
R5686 T8768 T8766 punct ", ",appeared
R5690 T8769 T8770 compound TGF,β2