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PMC:539061 / 28261-29262 JSONTXT 5 Projects

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Id Subject Object Predicate Lexical cue
T5480 0-1 FW denotes A
T5481 2-8 FW denotes priori
T5483 8-10 , denotes ,
T5484 10-13 DT denotes the
T5485 14-22 NN denotes decrease
T5486 23-25 IN denotes in
T5487 26-27 NN denotes α
T5489 27-28 HYPH denotes -
T5488 28-35 NN denotes catenin
T5490 36-42 NNS denotes levels
T5491 43-48 MD denotes could
T5482 49-51 VB denotes be
T5492 52-55 IN denotes due
T5493 56-58 IN denotes to
T5494 59-65 CC denotes either
T5496 66-72 JJ denotes direct
T5497 73-88 JJ denotes transcriptional
T5495 89-99 NN denotes repression
T5498 100-102 IN denotes by
T5499 103-108 NN denotes Snail
T5500 109-111 CC denotes or
T5501 112-125 NNS denotes perturbations
T5502 126-128 IN denotes in
T5503 129-131 NN denotes AJ
T5504 132-141 NN denotes formation
T5505 142-148 VBN denotes caused
T5506 149-151 IN denotes by
T5507 152-155 DT denotes the
T5508 156-164 NN denotes decrease
T5509 165-167 IN denotes in
T5510 168-169 NN denotes E
T5512 169-170 HYPH denotes -
T5511 170-178 NN denotes cadherin
T5514 179-183 NN denotes gene
T5513 184-194 NN denotes expression
T5515 194-195 . denotes .
T5516 195-365 sentence denotes To distinguish between these possibilities, we tested whether α-catenin levels could be restored by exogenous expression of E-cadherin in Snail-expressing keratinocytes.
T5517 196-198 TO denotes To
T5518 199-210 VB denotes distinguish
T5520 211-218 IN denotes between
T5521 219-224 DT denotes these
T5522 225-238 NNS denotes possibilities
T5523 238-240 , denotes ,
T5524 240-242 PRP denotes we
T5519 243-249 VBD denotes tested
T5525 250-257 IN denotes whether
T5527 258-259 NN denotes α
T5529 259-260 HYPH denotes -
T5528 260-267 NN denotes catenin
T5530 268-274 NNS denotes levels
T5531 275-280 MD denotes could
T5532 281-283 VB denotes be
T5526 284-292 VBN denotes restored
T5533 293-295 IN denotes by
T5534 296-305 JJ denotes exogenous
T5535 306-316 NN denotes expression
T5536 317-319 IN denotes of
T5537 320-321 NN denotes E
T5539 321-322 HYPH denotes -
T5538 322-330 NN denotes cadherin
T5540 331-333 IN denotes in
T5541 334-339 NN denotes Snail
T5543 339-340 HYPH denotes -
T5542 340-350 VBG denotes expressing
T5544 351-364 NNS denotes keratinocytes
T5545 364-365 . denotes .
T5546 365-520 sentence denotes As shown in Figure 4C, transiently transfected keratinocytes expressing HA-tagged Snail displayed a loss of E-cadherin and α-catenin at cell-cell borders.
T5547 366-368 IN denotes As
T5548 369-374 VBN denotes shown
T5550 375-377 IN denotes in
T5551 378-384 NN denotes Figure
T5552 385-387 NN denotes 4C
T5553 387-389 , denotes ,
T5554 389-400 RB denotes transiently
T5555 401-412 VBN denotes transfected
T5556 413-426 NNS denotes keratinocytes
T5557 427-437 VBG denotes expressing
T5558 438-440 NN denotes HA
T5560 440-441 HYPH denotes -
T5559 441-447 VBN denotes tagged
T5561 448-453 NN denotes Snail
T5549 454-463 VBD denotes displayed
T5562 464-465 DT denotes a
T5563 466-470 NN denotes loss
T5564 471-473 IN denotes of
T5565 474-475 NN denotes E
T5567 475-476 HYPH denotes -
T5566 476-484 NN denotes cadherin
T5568 485-488 CC denotes and
T5569 489-490 NN denotes α
T5571 490-491 HYPH denotes -
T5570 491-498 NN denotes catenin
T5572 499-501 IN denotes at
T5573 502-506 NN denotes cell
T5575 506-507 HYPH denotes -
T5574 507-511 NN denotes cell
T5576 512-519 NNS denotes borders
T5577 519-520 . denotes .
T5578 520-710 sentence denotes Coexpression of exogenous HA-tagged E-cadherin not only enabled cell-cell border localization of E-cadherin protein, but also rescued the cell-cell border staining of α-catenin (Figure 4C).
T5579 521-533 NN denotes Coexpression
T5581 534-536 IN denotes of
T5582 537-546 JJ denotes exogenous
T5584 547-549 NN denotes HA
T5586 549-550 HYPH denotes -
T5585 550-556 VBN denotes tagged
T5587 557-558 NN denotes E
T5588 558-559 HYPH denotes -
T5583 559-567 NN denotes cadherin
T5589 568-571 RB denotes not
T5590 572-576 RB denotes only
T5580 577-584 VBD denotes enabled
T5591 585-589 NN denotes cell
T5593 589-590 HYPH denotes -
T5592 590-594 NN denotes cell
T5595 595-601 NN denotes border
T5594 602-614 NN denotes localization
T5596 615-617 IN denotes of
T5597 618-619 NN denotes E
T5599 619-620 HYPH denotes -
T5598 620-628 NN denotes cadherin
T5600 629-636 NN denotes protein
T5601 636-638 , denotes ,
T5602 638-641 CC denotes but
T5603 642-646 RB denotes also
T5604 647-654 VBD denotes rescued
T5605 655-658 DT denotes the
T5607 659-663 NN denotes cell
T5609 663-664 HYPH denotes -
T5608 664-668 NN denotes cell
T5610 669-675 NN denotes border
T5606 676-684 NN denotes staining
T5611 685-687 IN denotes of
T5612 688-689 NN denotes α
T5614 689-690 HYPH denotes -
T5613 690-697 NN denotes catenin
T5615 698-699 -LRB- denotes (
T5617 699-705 NN denotes Figure
T5616 706-708 NN denotes 4C
T5618 708-709 -RRB- denotes )
T5619 709-710 . denotes .
T5620 710-870 sentence denotes The ability to restore α-catenin expression and localization under these conditions argues against the notion that Snail transcriptionally represses α-catenin.
T5621 711-714 DT denotes The
T5622 715-722 NN denotes ability
T5624 723-725 TO denotes to
T5625 726-733 VB denotes restore
T5626 734-735 NN denotes α
T5628 735-736 HYPH denotes -
T5627 736-743 NN denotes catenin
T5629 744-754 NN denotes expression
T5630 755-758 CC denotes and
T5631 759-771 NN denotes localization
T5632 772-777 IN denotes under
T5633 778-783 DT denotes these
T5634 784-794 NNS denotes conditions
T5623 795-801 VBZ denotes argues
T5635 802-809 IN denotes against
T5636 810-813 DT denotes the
T5637 814-820 NN denotes notion
T5638 821-825 IN denotes that
T5640 826-831 NN denotes Snail
T5641 832-849 RB denotes transcriptionally
T5639 850-859 VBZ denotes represses
T5642 860-861 NN denotes α
T5644 861-862 HYPH denotes -
T5643 862-869 NN denotes catenin
T5645 869-870 . denotes .
T5646 870-1001 sentence denotes Rather, the findings are consistent with a previous report that E-cadherin is required for the translation of α-catenin mRNA [22].
T5647 871-877 RB denotes Rather
T5649 877-879 , denotes ,
T5650 879-882 DT denotes the
T5651 883-891 NNS denotes findings
T5648 892-895 VBP denotes are
T5652 896-906 JJ denotes consistent
T5653 907-911 IN denotes with
T5654 912-913 DT denotes a
T5656 914-922 JJ denotes previous
T5655 923-929 NN denotes report
T5657 930-934 IN denotes that
T5659 935-936 NN denotes E
T5661 936-937 HYPH denotes -
T5660 937-945 NN denotes cadherin
T5662 946-948 VBZ denotes is
T5658 949-957 VBN denotes required
T5663 958-961 IN denotes for
T5664 962-965 DT denotes the
T5665 966-977 NN denotes translation
T5666 978-980 IN denotes of
T5667 981-982 NN denotes α
T5669 982-983 HYPH denotes -
T5668 983-990 NN denotes catenin
T5670 991-995 NN denotes mRNA
T5671 996-997 -LRB- denotes [
T5672 997-999 CD denotes 22
T5673 999-1000 -RRB- denotes ]
T5674 1000-1001 . denotes .
R3122 T5480 T5481 advmod A,priori
R3123 T5481 T5482 advmod priori,be
R3124 T5483 T5482 punct ", ",be
R3125 T5484 T5485 det the,decrease
R3126 T5485 T5482 nsubj decrease,be
R3127 T5486 T5485 prep in,decrease
R3128 T5487 T5488 compound α,catenin
R3129 T5488 T5490 compound catenin,levels
R3130 T5489 T5488 punct -,catenin
R3131 T5490 T5486 pobj levels,in
R3132 T5491 T5482 aux could,be
R3133 T5492 T5482 prep due,be
R3134 T5493 T5492 pcomp to,due
R3135 T5494 T5495 preconj either,repression
R3136 T5495 T5492 pobj repression,due
R3137 T5496 T5495 amod direct,repression
R3138 T5497 T5495 amod transcriptional,repression
R3139 T5498 T5495 prep by,repression
R3140 T5499 T5498 pobj Snail,by
R3141 T5500 T5495 cc or,repression
R3142 T5501 T5495 conj perturbations,repression
R3143 T5502 T5501 prep in,perturbations
R3144 T5503 T5504 compound AJ,formation
R3145 T5504 T5502 pobj formation,in
R3146 T5505 T5501 acl caused,perturbations
R3147 T5506 T5505 agent by,caused
R3148 T5507 T5508 det the,decrease
R3149 T5508 T5506 pobj decrease,by
R3150 T5509 T5508 prep in,decrease
R3151 T5510 T5511 compound E,cadherin
R3152 T5511 T5513 compound cadherin,expression
R3153 T5512 T5511 punct -,cadherin
R3154 T5513 T5509 pobj expression,in
R3155 T5514 T5513 compound gene,expression
R3156 T5515 T5482 punct .,be
R3157 T5517 T5518 aux To,distinguish
R3158 T5518 T5519 advcl distinguish,tested
R3159 T5520 T5518 prep between,distinguish
R3160 T5521 T5522 det these,possibilities
R3161 T5522 T5520 pobj possibilities,between
R3162 T5523 T5519 punct ", ",tested
R3163 T5524 T5519 nsubj we,tested
R3164 T5525 T5526 mark whether,restored
R3165 T5526 T5519 ccomp restored,tested
R3166 T5527 T5528 compound α,catenin
R3167 T5528 T5530 compound catenin,levels
R3168 T5529 T5528 punct -,catenin
R3169 T5530 T5526 nsubjpass levels,restored
R3170 T5531 T5526 aux could,restored
R3171 T5532 T5526 auxpass be,restored
R3172 T5533 T5526 agent by,restored
R3173 T5534 T5535 amod exogenous,expression
R3174 T5535 T5533 pobj expression,by
R3175 T5536 T5535 prep of,expression
R3176 T5537 T5538 compound E,cadherin
R3177 T5538 T5536 pobj cadherin,of
R3178 T5539 T5538 punct -,cadherin
R3179 T5540 T5526 prep in,restored
R3180 T5541 T5542 npadvmod Snail,expressing
R3181 T5542 T5544 amod expressing,keratinocytes
R3182 T5543 T5542 punct -,expressing
R3183 T5544 T5540 pobj keratinocytes,in
R3184 T5545 T5519 punct .,tested
R3185 T5547 T5548 mark As,shown
R3186 T5548 T5549 advcl shown,displayed
R3187 T5550 T5548 prep in,shown
R3188 T5551 T5552 compound Figure,4C
R3189 T5552 T5550 pobj 4C,in
R3190 T5553 T5549 punct ", ",displayed
R3191 T5554 T5555 advmod transiently,transfected
R3192 T5555 T5556 amod transfected,keratinocytes
R3193 T5556 T5549 nsubj keratinocytes,displayed
R3194 T5557 T5556 acl expressing,keratinocytes
R3195 T5558 T5559 npadvmod HA,tagged
R3196 T5559 T5561 amod tagged,Snail
R3197 T5560 T5559 punct -,tagged
R3198 T5561 T5557 dobj Snail,expressing
R3199 T5562 T5563 det a,loss
R3200 T5563 T5549 dobj loss,displayed
R3201 T5564 T5563 prep of,loss
R3202 T5565 T5566 compound E,cadherin
R3203 T5566 T5564 pobj cadherin,of
R3204 T5567 T5566 punct -,cadherin
R3205 T5568 T5566 cc and,cadherin
R3206 T5569 T5570 compound α,catenin
R3207 T5570 T5566 conj catenin,cadherin
R3208 T5571 T5570 punct -,catenin
R3209 T5572 T5549 prep at,displayed
R3210 T5573 T5574 compound cell,cell
R3211 T5574 T5576 compound cell,borders
R3212 T5575 T5574 punct -,cell
R3213 T5576 T5572 pobj borders,at
R3214 T5577 T5549 punct .,displayed
R3215 T5579 T5580 nsubj Coexpression,enabled
R3216 T5581 T5579 prep of,Coexpression
R3217 T5582 T5583 amod exogenous,cadherin
R3218 T5583 T5581 pobj cadherin,of
R3219 T5584 T5585 npadvmod HA,tagged
R3220 T5585 T5583 amod tagged,cadherin
R3221 T5586 T5585 punct -,tagged
R3222 T5587 T5583 compound E,cadherin
R3223 T5588 T5583 punct -,cadherin
R3224 T5589 T5580 preconj not,enabled
R3225 T5590 T5589 advmod only,not
R3226 T5591 T5592 compound cell,cell
R3227 T5592 T5594 compound cell,localization
R3228 T5593 T5592 punct -,cell
R3229 T5594 T5580 dobj localization,enabled
R3230 T5595 T5594 compound border,localization
R3231 T5596 T5594 prep of,localization
R3232 T5597 T5598 compound E,cadherin
R3233 T5598 T5600 compound cadherin,protein
R3234 T5599 T5598 punct -,cadherin
R3235 T5600 T5596 pobj protein,of
R3236 T5601 T5580 punct ", ",enabled
R3237 T5602 T5580 cc but,enabled
R3238 T5603 T5602 advmod also,but
R3239 T5604 T5580 conj rescued,enabled
R3240 T5605 T5606 det the,staining
R3241 T5606 T5604 dobj staining,rescued
R3242 T5607 T5608 compound cell,cell
R3243 T5608 T5606 compound cell,staining
R3244 T5609 T5608 punct -,cell
R3245 T5610 T5606 compound border,staining
R3246 T5611 T5606 prep of,staining
R3247 T5612 T5613 compound α,catenin
R3248 T5613 T5611 pobj catenin,of
R3249 T5614 T5613 punct -,catenin
R3250 T5615 T5616 punct (,4C
R3251 T5616 T5604 parataxis 4C,rescued
R3252 T5617 T5616 compound Figure,4C
R3253 T5618 T5616 punct ),4C
R3254 T5619 T5580 punct .,enabled
R3255 T5621 T5622 det The,ability
R3256 T5622 T5623 nsubj ability,argues
R3257 T5624 T5625 aux to,restore
R3258 T5625 T5622 acl restore,ability
R3259 T5626 T5627 compound α,catenin
R3260 T5627 T5625 dobj catenin,restore
R3261 T5628 T5627 punct -,catenin
R3262 T5629 T5627 appos expression,catenin
R3263 T5630 T5629 cc and,expression
R3264 T5631 T5629 conj localization,expression
R3265 T5632 T5625 prep under,restore
R3266 T5633 T5634 det these,conditions
R3267 T5634 T5632 pobj conditions,under
R3268 T5635 T5623 prep against,argues
R3269 T5636 T5637 det the,notion
R3270 T5637 T5635 pobj notion,against
R3271 T5638 T5639 mark that,represses
R3272 T5639 T5637 acl represses,notion
R3273 T5640 T5639 nsubj Snail,represses
R3274 T5641 T5639 advmod transcriptionally,represses
R3275 T5642 T5643 compound α,catenin
R3276 T5643 T5639 dobj catenin,represses
R3277 T5644 T5643 punct -,catenin
R3278 T5645 T5623 punct .,argues
R3279 T5647 T5648 advmod Rather,are
R3280 T5649 T5648 punct ", ",are
R3281 T5650 T5651 det the,findings
R3282 T5651 T5648 nsubj findings,are
R3283 T5652 T5648 acomp consistent,are
R3284 T5653 T5652 prep with,consistent
R3285 T5654 T5655 det a,report
R3286 T5655 T5653 pobj report,with
R3287 T5656 T5655 amod previous,report
R3288 T5657 T5658 mark that,required
R3289 T5658 T5655 acl required,report
R3290 T5659 T5660 compound E,cadherin
R3291 T5660 T5658 nsubjpass cadherin,required
R3292 T5661 T5660 punct -,cadherin
R3293 T5662 T5658 auxpass is,required
R3294 T5663 T5658 prep for,required
R3295 T5664 T5665 det the,translation
R3296 T5665 T5663 pobj translation,for
R3297 T5666 T5665 prep of,translation
R3298 T5667 T5668 compound α,catenin
R3299 T5668 T5670 compound catenin,mRNA
R3300 T5669 T5668 punct -,catenin
R3301 T5670 T5666 pobj mRNA,of
R3302 T5671 T5672 punct [,22
R3303 T5672 T5648 parataxis 22,are
R3304 T5673 T5672 punct ],22
R3305 T5674 T5648 punct .,are