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PMC:314463 / 101-2120 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T179 0-4 JJ denotes Many
T180 5-12 NNS denotes members
T182 13-15 IN denotes of
T183 16-19 DT denotes the
T185 20-26 NN denotes animal
T184 27-34 NN denotes kingdom
T181 35-42 VBP denotes display
T186 43-47 NN denotes coat
T188 48-50 CC denotes or
T189 51-55 NN denotes skin
T190 56-61 NN denotes color
T187 62-73 NNS denotes differences
T191 74-79 IN denotes along
T192 80-85 PRP$ denotes their
T194 86-98 JJ denotes dorsoventral
T193 99-103 NN denotes axis
T195 103-104 . denotes .
T196 104-343 sentence denotes To determine the mechanisms that control regional differences in pigmentation, we have studied how a classical mouse mutation, droopy ear (deH), affects dorsoventral skin characteristics, especially those under control of the Agouti gene.
T197 105-107 TO denotes To
T198 108-117 VB denotes determine
T200 118-121 DT denotes the
T201 122-132 NNS denotes mechanisms
T202 133-137 WDT denotes that
T203 138-145 VBP denotes control
T204 146-154 JJ denotes regional
T205 155-166 NNS denotes differences
T206 167-169 IN denotes in
T207 170-182 NN denotes pigmentation
T208 182-184 , denotes ,
T209 184-186 PRP denotes we
T210 187-191 VBP denotes have
T199 192-199 VBN denotes studied
T211 200-203 WRB denotes how
T213 204-205 DT denotes a
T215 206-215 JJ denotes classical
T216 216-221 NN denotes mouse
T214 222-230 NN denotes mutation
T217 230-232 , denotes ,
T218 232-238 JJ denotes droopy
T219 239-242 NN denotes ear
T220 243-244 -LRB- denotes (
T221 244-247 NN denotes deH
T222 247-248 -RRB- denotes )
T223 248-250 , denotes ,
T212 250-257 VBZ denotes affects
T224 258-270 JJ denotes dorsoventral
T226 271-275 NN denotes skin
T225 276-291 NNS denotes characteristics
T227 291-293 , denotes ,
T228 293-303 RB denotes especially
T229 304-309 DT denotes those
T230 310-315 IN denotes under
T231 316-323 NN denotes control
T232 324-326 IN denotes of
T233 327-330 DT denotes the
T235 331-337 NN denotes Agouti
T234 338-342 NN denotes gene
T236 342-343 . denotes .
T237 343-583 sentence denotes Mice carrying the Agouti allele black-and-tan (at) normally have a sharp boundary between dorsal black hair and yellow ventral hair; the deH mutation raises the pigmentation boundary, producing an apparent dorsal-to-ventral transformation.
T238 344-348 NNS denotes Mice
T240 349-357 VBG denotes carrying
T241 358-361 DT denotes the
T243 362-368 NN denotes Agouti
T242 369-375 NN denotes allele
T244 376-381 NN denotes black
T245 381-382 HYPH denotes -
T246 382-385 CC denotes and
T247 385-386 HYPH denotes -
T248 386-389 NN denotes tan
T249 390-391 -LRB- denotes (
T250 391-393 NN denotes at
T251 393-394 -RRB- denotes )
T252 395-403 RB denotes normally
T239 404-408 VBP denotes have
T254 409-410 DT denotes a
T256 411-416 JJ denotes sharp
T255 417-425 NN denotes boundary
T257 426-433 IN denotes between
T258 434-440 JJ denotes dorsal
T260 441-446 JJ denotes black
T259 447-451 NN denotes hair
T261 452-455 CC denotes and
T262 456-462 JJ denotes yellow
T264 463-470 JJ denotes ventral
T263 471-475 NN denotes hair
T265 475-476 : denotes ;
T266 477-480 DT denotes the
T268 481-484 NN denotes deH
T267 485-493 NN denotes mutation
T253 494-500 VBZ denotes raises
T269 501-504 DT denotes the
T271 505-517 NN denotes pigmentation
T270 518-526 NN denotes boundary
T272 526-528 , denotes ,
T273 528-537 VBG denotes producing
T274 538-540 DT denotes an
T276 541-549 JJ denotes apparent
T277 550-556 JJ denotes dorsal
T278 556-557 HYPH denotes -
T279 557-559 IN denotes to
T280 559-560 HYPH denotes -
T281 560-567 JJ denotes ventral
T275 568-582 NN denotes transformation
T282 582-583 . denotes .
T283 583-810 sentence denotes We identify a 216 kb deletion in deH that removes all but the first exon of the Tbx15 gene, whose embryonic expression in developing mesenchyme correlates with pigmentary and skeletal malformations observed in deH/deH animals.
T284 584-586 PRP denotes We
T285 587-595 VBP denotes identify
T286 596-597 DT denotes a
T288 598-601 CD denotes 216
T289 602-604 NN denotes kb
T287 605-613 NN denotes deletion
T290 614-616 IN denotes in
T291 617-620 NN denotes deH
T292 621-625 WDT denotes that
T293 626-633 VBZ denotes removes
T294 634-637 DT denotes all
T295 638-641 IN denotes but
T296 642-645 DT denotes the
T298 646-651 JJ denotes first
T297 652-656 NN denotes exon
T299 657-659 IN denotes of
T300 660-663 DT denotes the
T302 664-669 NN denotes Tbx15
T301 670-674 NN denotes gene
T303 674-676 , denotes ,
T304 676-681 WP$ denotes whose
T306 682-691 JJ denotes embryonic
T305 692-702 NN denotes expression
T308 703-705 IN denotes in
T309 706-716 VBG denotes developing
T310 717-727 NN denotes mesenchyme
T307 728-738 VBZ denotes correlates
T311 739-743 IN denotes with
T312 744-754 JJ denotes pigmentary
T314 755-758 CC denotes and
T315 759-767 JJ denotes skeletal
T313 768-781 NNS denotes malformations
T316 782-790 VBN denotes observed
T317 791-793 IN denotes in
T318 794-797 NN denotes deH
T320 797-798 HYPH denotes /
T319 798-801 NN denotes deH
T321 802-809 NNS denotes animals
T322 809-810 . denotes .
T323 810-924 sentence denotes Construction of a targeted allele of Tbx15 confirmed that the deH phenotype was caused by Tbx15 loss of function.
T324 811-823 NN denotes Construction
T326 824-826 IN denotes of
T327 827-828 DT denotes a
T329 829-837 VBN denotes targeted
T328 838-844 NN denotes allele
T330 845-847 IN denotes of
T331 848-853 NN denotes Tbx15
T325 854-863 VBD denotes confirmed
T332 864-868 IN denotes that
T334 869-872 DT denotes the
T336 873-876 NN denotes deH
T335 877-886 NN denotes phenotype
T337 887-890 VBD denotes was
T333 891-897 VBN denotes caused
T338 898-900 IN denotes by
T339 901-906 NN denotes Tbx15
T340 907-911 NN denotes loss
T341 912-914 IN denotes of
T342 915-923 NN denotes function
T343 923-924 . denotes .
T344 924-1149 sentence denotes Early embryonic expression of Tbx15 in dorsal mesenchyme is complementary to Agouti expression in ventral mesenchyme; in the absence of Tbx15, expression of Agouti in both embryos and postnatal animals is displaced dorsally.
T345 925-930 RB denotes Early
T346 931-940 JJ denotes embryonic
T347 941-951 NN denotes expression
T349 952-954 IN denotes of
T350 955-960 NN denotes Tbx15
T351 961-963 IN denotes in
T352 964-970 JJ denotes dorsal
T353 971-981 NN denotes mesenchyme
T348 982-984 VBZ denotes is
T355 985-998 JJ denotes complementary
T356 999-1001 IN denotes to
T357 1002-1008 NN denotes Agouti
T358 1009-1019 NN denotes expression
T359 1020-1022 IN denotes in
T360 1023-1030 JJ denotes ventral
T361 1031-1041 NN denotes mesenchyme
T362 1041-1042 : denotes ;
T363 1043-1045 IN denotes in
T364 1046-1049 DT denotes the
T365 1050-1057 NN denotes absence
T366 1058-1060 IN denotes of
T367 1061-1066 NN denotes Tbx15
T368 1066-1068 , denotes ,
T369 1068-1078 NN denotes expression
T370 1079-1081 IN denotes of
T371 1082-1088 NN denotes Agouti
T372 1089-1091 IN denotes in
T373 1092-1096 CC denotes both
T374 1097-1104 NNS denotes embryos
T375 1105-1108 CC denotes and
T376 1109-1118 JJ denotes postnatal
T377 1119-1126 NNS denotes animals
T378 1127-1129 VBZ denotes is
T354 1130-1139 VBN denotes displaced
T379 1140-1148 RB denotes dorsally
T380 1148-1149 . denotes .
T381 1149-1361 sentence denotes Transplantation experiments demonstrate that positional identity of the skin with regard to dorsoventral pigmentation differences is acquired by E12.5, which is shortly after early embryonic expression of Tbx15.
T382 1150-1165 NN denotes Transplantation
T383 1166-1177 NNS denotes experiments
T384 1178-1189 VBP denotes demonstrate
T385 1190-1194 IN denotes that
T387 1195-1205 JJ denotes positional
T388 1206-1214 NN denotes identity
T389 1215-1217 IN denotes of
T390 1218-1221 DT denotes the
T391 1222-1226 NN denotes skin
T392 1227-1231 IN denotes with
T393 1232-1238 NN denotes regard
T394 1239-1241 IN denotes to
T395 1242-1254 JJ denotes dorsoventral
T397 1255-1267 NN denotes pigmentation
T396 1268-1279 NNS denotes differences
T398 1280-1282 VBZ denotes is
T386 1283-1291 VBN denotes acquired
T399 1292-1294 IN denotes by
T400 1295-1300 NN denotes E12.5
T401 1300-1302 , denotes ,
T402 1302-1307 WDT denotes which
T403 1308-1310 VBZ denotes is
T404 1311-1318 RB denotes shortly
T405 1319-1324 IN denotes after
T406 1325-1330 RB denotes early
T407 1331-1340 JJ denotes embryonic
T408 1341-1351 NN denotes expression
T409 1352-1354 IN denotes of
T410 1355-1360 NN denotes Tbx15
T411 1360-1361 . denotes .
T412 1361-1557 sentence denotes Fate-mapping studies show that the dorsoventral pigmentation boundary is not in register with a previously identified dermal cell lineage boundary, but rather with the limb dorsoventral boundary.
T413 1362-1366 NN denotes Fate
T415 1366-1367 HYPH denotes -
T414 1367-1374 VBG denotes mapping
T416 1375-1382 NNS denotes studies
T417 1383-1387 VBP denotes show
T418 1388-1392 IN denotes that
T420 1393-1396 DT denotes the
T422 1397-1409 JJ denotes dorsoventral
T423 1410-1422 NN denotes pigmentation
T421 1423-1431 NN denotes boundary
T419 1432-1434 VBZ denotes is
T424 1435-1438 RB denotes not
T425 1439-1441 IN denotes in
T426 1442-1450 NN denotes register
T427 1451-1455 IN denotes with
T428 1456-1457 DT denotes a
T430 1458-1468 RB denotes previously
T431 1469-1479 VBN denotes identified
T432 1480-1486 JJ denotes dermal
T433 1487-1491 NN denotes cell
T434 1492-1499 NN denotes lineage
T429 1500-1508 NN denotes boundary
T435 1508-1510 , denotes ,
T436 1510-1513 CC denotes but
T437 1514-1520 RB denotes rather
T438 1521-1525 IN denotes with
T439 1526-1529 DT denotes the
T441 1530-1534 NN denotes limb
T442 1535-1547 JJ denotes dorsoventral
T440 1548-1556 NN denotes boundary
T443 1556-1557 . denotes .
T444 1557-1715 sentence denotes Embryonic expression of Tbx15 in dorsolateral mesenchyme provides an instructional cue required to establish the future positional identity of dorsal dermis.
T445 1558-1567 JJ denotes Embryonic
T446 1568-1578 NN denotes expression
T448 1579-1581 IN denotes of
T449 1582-1587 NN denotes Tbx15
T450 1588-1590 IN denotes in
T451 1591-1603 JJ denotes dorsolateral
T452 1604-1614 NN denotes mesenchyme
T447 1615-1623 VBZ denotes provides
T453 1624-1626 DT denotes an
T455 1627-1640 JJ denotes instructional
T454 1641-1644 NN denotes cue
T456 1645-1653 VBN denotes required
T457 1654-1656 TO denotes to
T458 1657-1666 VB denotes establish
T459 1667-1670 DT denotes the
T461 1671-1677 JJ denotes future
T462 1678-1688 JJ denotes positional
T460 1689-1697 NN denotes identity
T463 1698-1700 IN denotes of
T464 1701-1707 JJ denotes dorsal
T465 1708-1714 NN denotes dermis
T466 1714-1715 . denotes .
T467 1715-2019 sentence denotes These findings represent a novel role for T-box gene action in embryonic development, identify a previously unappreciated aspect of dorsoventral patterning that is widely represented in furred mammals, and provide insight into the mechanisms that underlie region-specific differences in body morphology.
T468 1716-1721 DT denotes These
T469 1722-1730 NNS denotes findings
T470 1731-1740 VBP denotes represent
T471 1741-1742 DT denotes a
T473 1743-1748 JJ denotes novel
T472 1749-1753 NN denotes role
T474 1754-1757 IN denotes for
T475 1758-1759 NN denotes T
T477 1759-1760 HYPH denotes -
T476 1760-1763 NN denotes box
T479 1764-1768 NN denotes gene
T478 1769-1775 NN denotes action
T480 1776-1778 IN denotes in
T481 1779-1788 JJ denotes embryonic
T482 1789-1800 NN denotes development
T483 1800-1802 , denotes ,
T484 1802-1810 VBP denotes identify
T485 1811-1812 DT denotes a
T487 1813-1823 RB denotes previously
T488 1824-1837 JJ denotes unappreciated
T486 1838-1844 NN denotes aspect
T489 1845-1847 IN denotes of
T490 1848-1860 JJ denotes dorsoventral
T491 1861-1871 NN denotes patterning
T492 1872-1876 WDT denotes that
T494 1877-1879 VBZ denotes is
T495 1880-1886 RB denotes widely
T493 1887-1898 VBN denotes represented
T496 1899-1901 IN denotes in
T497 1902-1908 VBN denotes furred
T498 1909-1916 NNS denotes mammals
T499 1916-1918 , denotes ,
T500 1918-1921 CC denotes and
T501 1922-1929 VBP denotes provide
T502 1930-1937 NN denotes insight
T503 1938-1942 IN denotes into
T504 1943-1946 DT denotes the
T505 1947-1957 NNS denotes mechanisms
T506 1958-1962 WDT denotes that
T507 1963-1971 VBP denotes underlie
T508 1972-1978 NN denotes region
T510 1978-1979 HYPH denotes -
T509 1979-1987 JJ denotes specific
T511 1988-1999 NNS denotes differences
T512 2000-2002 IN denotes in
T513 2003-2007 NN denotes body
T514 2008-2018 NN denotes morphology
T515 2018-2019 . denotes .
R10 T183 T184 det the,kingdom
R100 T277 T275 amod dorsal,transformation
R101 T278 T277 punct -,dorsal
R102 T279 T277 prep to,dorsal
R103 T280 T279 punct -,to
R104 T281 T279 amod ventral,to
R105 T282 T253 punct .,raises
R106 T284 T285 nsubj We,identify
R107 T286 T287 det a,deletion
R108 T287 T285 dobj deletion,identify
R109 T288 T289 nummod 216,kb
R11 T184 T182 pobj kingdom,of
R110 T289 T287 compound kb,deletion
R111 T290 T287 prep in,deletion
R112 T291 T290 pobj deH,in
R113 T292 T293 dep that,removes
R114 T293 T287 relcl removes,deletion
R115 T294 T293 dobj all,removes
R116 T295 T294 prep but,all
R117 T296 T297 det the,exon
R118 T297 T295 pobj exon,but
R119 T298 T297 amod first,exon
R12 T185 T184 compound animal,kingdom
R120 T299 T297 prep of,exon
R121 T300 T301 det the,gene
R122 T301 T299 pobj gene,of
R123 T302 T301 compound Tbx15,gene
R124 T303 T297 punct ", ",exon
R125 T304 T305 poss whose,expression
R126 T305 T307 dep expression,correlates
R127 T306 T305 amod embryonic,expression
R128 T307 T297 relcl correlates,exon
R129 T308 T305 prep in,expression
R13 T186 T187 nmod coat,differences
R130 T309 T310 amod developing,mesenchyme
R131 T310 T308 pobj mesenchyme,in
R132 T311 T307 prep with,correlates
R133 T312 T313 amod pigmentary,malformations
R134 T313 T311 pobj malformations,with
R135 T314 T312 cc and,pigmentary
R136 T315 T312 conj skeletal,pigmentary
R137 T316 T313 acl observed,malformations
R138 T317 T316 prep in,observed
R139 T318 T319 compound deH,deH
R14 T187 T181 dobj differences,display
R140 T319 T321 compound deH,animals
R141 T320 T319 punct /,deH
R142 T321 T317 pobj animals,in
R143 T322 T285 punct .,identify
R144 T324 T325 nsubj Construction,confirmed
R145 T326 T324 prep of,Construction
R146 T327 T328 det a,allele
R147 T328 T326 pobj allele,of
R148 T329 T328 amod targeted,allele
R149 T330 T328 prep of,allele
R15 T188 T186 cc or,coat
R150 T331 T330 pobj Tbx15,of
R151 T332 T333 mark that,caused
R152 T333 T325 ccomp caused,confirmed
R153 T334 T335 det the,phenotype
R154 T335 T333 nsubjpass phenotype,caused
R155 T336 T335 compound deH,phenotype
R156 T337 T333 auxpass was,caused
R157 T338 T333 agent by,caused
R158 T339 T340 compound Tbx15,loss
R159 T340 T338 pobj loss,by
R16 T189 T190 compound skin,color
R160 T341 T340 prep of,loss
R161 T342 T341 pobj function,of
R162 T343 T325 punct .,confirmed
R163 T345 T346 advmod Early,embryonic
R164 T346 T347 amod embryonic,expression
R165 T347 T348 nsubj expression,is
R166 T348 T354 ccomp is,displaced
R167 T349 T347 prep of,expression
R168 T350 T349 pobj Tbx15,of
R169 T351 T347 prep in,expression
R17 T190 T186 conj color,coat
R170 T352 T353 amod dorsal,mesenchyme
R171 T353 T351 pobj mesenchyme,in
R172 T355 T348 acomp complementary,is
R173 T356 T355 prep to,complementary
R174 T357 T358 compound Agouti,expression
R175 T358 T356 pobj expression,to
R176 T359 T358 prep in,expression
R177 T360 T361 amod ventral,mesenchyme
R178 T361 T359 pobj mesenchyme,in
R179 T362 T354 punct ;,displaced
R18 T191 T181 prep along,display
R180 T363 T354 prep in,displaced
R181 T364 T365 det the,absence
R182 T365 T363 pobj absence,in
R183 T366 T365 prep of,absence
R184 T367 T366 pobj Tbx15,of
R185 T368 T354 punct ", ",displaced
R186 T369 T354 nsubjpass expression,displaced
R187 T370 T369 prep of,expression
R188 T371 T370 pobj Agouti,of
R189 T372 T369 prep in,expression
R19 T192 T193 poss their,axis
R190 T373 T374 preconj both,embryos
R191 T374 T372 pobj embryos,in
R192 T375 T374 cc and,embryos
R193 T376 T377 amod postnatal,animals
R194 T377 T374 conj animals,embryos
R195 T378 T354 auxpass is,displaced
R196 T379 T354 advmod dorsally,displaced
R197 T380 T354 punct .,displaced
R198 T382 T383 compound Transplantation,experiments
R199 T383 T384 nsubj experiments,demonstrate
R20 T193 T191 pobj axis,along
R200 T385 T386 mark that,acquired
R201 T386 T384 ccomp acquired,demonstrate
R202 T387 T388 amod positional,identity
R203 T388 T386 nsubjpass identity,acquired
R204 T389 T388 prep of,identity
R205 T390 T391 det the,skin
R206 T391 T389 pobj skin,of
R207 T392 T388 prep with,identity
R208 T393 T392 pobj regard,with
R209 T394 T393 prep to,regard
R21 T194 T193 amod dorsoventral,axis
R210 T395 T396 amod dorsoventral,differences
R211 T396 T394 pobj differences,to
R212 T397 T396 compound pigmentation,differences
R213 T398 T386 auxpass is,acquired
R214 T399 T386 prep by,acquired
R215 T400 T399 pobj E12.5,by
R216 T401 T386 punct ", ",acquired
R217 T402 T403 dep which,is
R218 T403 T386 advcl is,acquired
R219 T404 T405 advmod shortly,after
R22 T195 T181 punct .,display
R220 T405 T403 prep after,is
R221 T406 T407 advmod early,embryonic
R222 T407 T408 amod embryonic,expression
R223 T408 T405 pobj expression,after
R224 T409 T408 prep of,expression
R225 T410 T409 pobj Tbx15,of
R226 T411 T384 punct .,demonstrate
R227 T413 T414 npadvmod Fate,mapping
R228 T414 T416 amod mapping,studies
R229 T415 T414 punct -,mapping
R23 T197 T198 aux To,determine
R230 T416 T417 nsubj studies,show
R231 T418 T419 mark that,is
R232 T419 T417 ccomp is,show
R233 T420 T421 det the,boundary
R234 T421 T419 nsubj boundary,is
R235 T422 T421 amod dorsoventral,boundary
R236 T423 T421 compound pigmentation,boundary
R237 T424 T419 neg not,is
R238 T425 T419 prep in,is
R239 T426 T425 pobj register,in
R24 T198 T199 advcl determine,studied
R240 T427 T426 prep with,register
R241 T428 T429 det a,boundary
R242 T429 T427 pobj boundary,with
R243 T430 T431 advmod previously,identified
R244 T431 T429 amod identified,boundary
R245 T432 T433 amod dermal,cell
R246 T433 T434 compound cell,lineage
R247 T434 T429 compound lineage,boundary
R248 T435 T419 punct ", ",is
R249 T436 T419 cc but,is
R25 T200 T201 det the,mechanisms
R250 T437 T419 conj rather,is
R251 T438 T437 prep with,rather
R252 T439 T440 det the,boundary
R253 T440 T438 pobj boundary,with
R254 T441 T440 nmod limb,boundary
R255 T442 T440 amod dorsoventral,boundary
R256 T443 T417 punct .,show
R257 T445 T446 amod Embryonic,expression
R258 T446 T447 nsubj expression,provides
R259 T448 T446 prep of,expression
R26 T201 T198 dobj mechanisms,determine
R260 T449 T448 pobj Tbx15,of
R261 T450 T446 prep in,expression
R262 T451 T452 amod dorsolateral,mesenchyme
R263 T452 T450 pobj mesenchyme,in
R264 T453 T454 det an,cue
R265 T454 T447 dobj cue,provides
R266 T455 T454 amod instructional,cue
R267 T456 T454 acl required,cue
R268 T457 T458 aux to,establish
R269 T458 T456 advcl establish,required
R27 T202 T203 dep that,control
R270 T459 T460 det the,identity
R271 T460 T458 dobj identity,establish
R272 T461 T460 amod future,identity
R273 T462 T460 amod positional,identity
R274 T463 T460 prep of,identity
R275 T464 T465 amod dorsal,dermis
R276 T465 T463 pobj dermis,of
R277 T466 T447 punct .,provides
R278 T468 T469 det These,findings
R279 T469 T470 nsubj findings,represent
R28 T203 T201 relcl control,mechanisms
R280 T471 T472 det a,role
R281 T472 T470 dobj role,represent
R282 T473 T472 amod novel,role
R283 T474 T472 prep for,role
R284 T475 T476 compound T,box
R285 T476 T478 compound box,action
R286 T477 T476 punct -,box
R287 T478 T474 pobj action,for
R288 T479 T478 compound gene,action
R289 T480 T472 prep in,role
R29 T204 T205 amod regional,differences
R290 T481 T482 amod embryonic,development
R291 T482 T480 pobj development,in
R292 T483 T470 punct ", ",represent
R293 T484 T470 conj identify,represent
R294 T485 T486 det a,aspect
R295 T486 T484 dobj aspect,identify
R296 T487 T488 advmod previously,unappreciated
R297 T488 T486 amod unappreciated,aspect
R298 T489 T486 prep of,aspect
R299 T490 T491 amod dorsoventral,patterning
R30 T205 T203 dobj differences,control
R300 T491 T489 pobj patterning,of
R301 T492 T493 dep that,represented
R302 T493 T486 relcl represented,aspect
R303 T494 T493 auxpass is,represented
R304 T495 T493 advmod widely,represented
R305 T496 T493 prep in,represented
R306 T497 T498 amod furred,mammals
R307 T498 T496 pobj mammals,in
R308 T499 T484 punct ", ",identify
R309 T500 T484 cc and,identify
R31 T206 T205 prep in,differences
R310 T501 T484 conj provide,identify
R311 T502 T501 dobj insight,provide
R312 T503 T502 prep into,insight
R313 T504 T505 det the,mechanisms
R314 T505 T503 pobj mechanisms,into
R315 T506 T507 dep that,underlie
R316 T507 T505 relcl underlie,mechanisms
R317 T508 T509 npadvmod region,specific
R318 T509 T511 amod specific,differences
R319 T510 T509 punct -,specific
R32 T207 T206 pobj pigmentation,in
R320 T511 T507 dobj differences,underlie
R321 T512 T511 prep in,differences
R322 T513 T514 compound body,morphology
R323 T514 T512 pobj morphology,in
R324 T515 T470 punct .,represent
R33 T208 T199 punct ", ",studied
R34 T209 T199 nsubj we,studied
R35 T210 T199 aux have,studied
R36 T211 T212 advmod how,affects
R37 T212 T199 ccomp affects,studied
R38 T213 T214 det a,mutation
R39 T214 T212 nsubj mutation,affects
R40 T215 T214 amod classical,mutation
R41 T216 T214 compound mouse,mutation
R42 T217 T214 punct ", ",mutation
R43 T218 T219 amod droopy,ear
R44 T219 T214 appos ear,mutation
R45 T220 T219 punct (,ear
R46 T221 T219 appos deH,ear
R47 T222 T219 punct ),ear
R48 T223 T212 punct ", ",affects
R49 T224 T225 amod dorsoventral,characteristics
R50 T225 T212 dobj characteristics,affects
R51 T226 T225 compound skin,characteristics
R52 T227 T225 punct ", ",characteristics
R53 T228 T229 advmod especially,those
R54 T229 T225 appos those,characteristics
R55 T230 T229 prep under,those
R56 T231 T230 pobj control,under
R57 T232 T231 prep of,control
R58 T233 T234 det the,gene
R59 T234 T232 pobj gene,of
R60 T235 T234 compound Agouti,gene
R61 T236 T199 punct .,studied
R62 T238 T239 nsubj Mice,have
R63 T239 T253 ccomp have,raises
R64 T240 T238 acl carrying,Mice
R65 T241 T242 det the,allele
R66 T242 T240 dobj allele,carrying
R67 T243 T242 compound Agouti,allele
R68 T244 T242 appos black,allele
R69 T245 T244 punct -,black
R7 T179 T180 amod Many,members
R70 T246 T244 cc and,black
R71 T247 T248 punct -,tan
R72 T248 T244 conj tan,black
R73 T249 T244 punct (,black
R74 T250 T244 appos at,black
R75 T251 T239 punct ),have
R76 T252 T239 advmod normally,have
R77 T254 T255 det a,boundary
R78 T255 T239 dobj boundary,have
R79 T256 T255 amod sharp,boundary
R8 T180 T181 nsubj members,display
R80 T257 T255 prep between,boundary
R81 T258 T259 amod dorsal,hair
R82 T259 T257 pobj hair,between
R83 T260 T259 amod black,hair
R84 T261 T259 cc and,hair
R85 T262 T263 amod yellow,hair
R86 T263 T259 conj hair,hair
R87 T264 T263 amod ventral,hair
R88 T265 T253 punct ;,raises
R89 T266 T267 det the,mutation
R9 T182 T180 prep of,members
R90 T267 T253 nsubj mutation,raises
R91 T268 T267 compound deH,mutation
R92 T269 T270 det the,boundary
R93 T270 T253 dobj boundary,raises
R94 T271 T270 compound pigmentation,boundary
R95 T272 T253 punct ", ",raises
R96 T273 T253 advcl producing,raises
R97 T274 T275 det an,transformation
R98 T275 T273 dobj transformation,producing
R99 T276 T275 amod apparent,transformation