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PMC:149350 / 105-731 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T153 0-10 sentence denotes Background
T154 0-10 NN denotes Background
T155 10-193 sentence denotes One approach to resolving some of the in vivo functions of alpha-crystallin is to generate animal models where one or both of the alpha-crystallin gene products have been eliminated.
T156 11-14 CD denotes One
T157 15-23 NN denotes approach
T159 24-26 IN denotes to
T160 27-36 VBG denotes resolving
T161 37-41 DT denotes some
T162 42-44 IN denotes of
T163 45-48 DT denotes the
T165 49-51 FW denotes in
T166 52-56 FW denotes vivo
T164 57-66 NNS denotes functions
T167 67-69 IN denotes of
T168 70-75 NN denotes alpha
T170 75-76 HYPH denotes -
T169 76-86 NN denotes crystallin
T158 87-89 VBZ denotes is
T171 90-92 TO denotes to
T172 93-101 VB denotes generate
T173 102-108 NN denotes animal
T174 109-115 NNS denotes models
T175 116-121 WRB denotes where
T177 122-125 CD denotes one
T178 126-128 CC denotes or
T179 129-133 DT denotes both
T180 134-136 IN denotes of
T181 137-140 DT denotes the
T183 141-146 NN denotes alpha
T185 146-147 HYPH denotes -
T184 147-157 NN denotes crystallin
T186 158-162 NN denotes gene
T182 163-171 NNS denotes products
T187 172-176 VBP denotes have
T188 177-181 VBN denotes been
T176 182-192 VBN denotes eliminated
T189 192-193 . denotes .
T190 193-446 sentence denotes In the single alpha-crystallin knockout mice, the remaining alpha-crystallin may fully or partially compensate for some of the functions of the missing protein, especially in the lens, where both alphaA and alphaB are normally expressed at high levels.
T191 194-196 IN denotes In
T193 197-200 DT denotes the
T195 201-207 JJ denotes single
T197 208-213 NN denotes alpha
T199 213-214 HYPH denotes -
T198 214-224 NN denotes crystallin
T196 225-233 NN denotes knockout
T194 234-238 NNS denotes mice
T200 238-240 , denotes ,
T201 240-243 DT denotes the
T203 244-253 VBG denotes remaining
T204 254-259 NN denotes alpha
T205 259-260 HYPH denotes -
T202 260-270 NN denotes crystallin
T206 271-274 MD denotes may
T207 275-280 RB denotes fully
T208 281-283 CC denotes or
T209 284-293 RB denotes partially
T192 294-304 VB denotes compensate
T210 305-308 IN denotes for
T211 309-313 DT denotes some
T212 314-316 IN denotes of
T213 317-320 DT denotes the
T214 321-330 NNS denotes functions
T215 331-333 IN denotes of
T216 334-337 DT denotes the
T218 338-345 VBG denotes missing
T217 346-353 NN denotes protein
T219 353-355 , denotes ,
T220 355-365 RB denotes especially
T221 366-368 IN denotes in
T222 369-372 DT denotes the
T223 373-377 NN denotes lens
T224 377-379 , denotes ,
T225 379-384 WRB denotes where
T227 385-389 CC denotes both
T228 390-396 NN denotes alphaA
T229 397-400 CC denotes and
T230 401-407 NN denotes alphaB
T231 408-411 VBP denotes are
T232 412-420 RB denotes normally
T226 421-430 VBN denotes expressed
T233 431-433 IN denotes at
T234 434-438 JJ denotes high
T235 439-445 NNS denotes levels
T236 445-446 . denotes .
T237 446-626 sentence denotes The purpose of this study was to characterize gross lenticular morphology in normal mice and mice with the targeted disruption of alphaA- and alphaB-crystallin genes (alphaA/BKO).
T238 447-450 DT denotes The
T239 451-458 NN denotes purpose
T241 459-461 IN denotes of
T242 462-466 DT denotes this
T243 467-472 NN denotes study
T240 473-476 VBD denotes was
T244 477-479 TO denotes to
T245 480-492 VB denotes characterize
T246 493-498 JJ denotes gross
T248 499-509 JJ denotes lenticular
T247 510-520 NN denotes morphology
T249 521-523 IN denotes in
T250 524-530 JJ denotes normal
T251 531-535 NNS denotes mice
T252 536-539 CC denotes and
T253 540-544 NNS denotes mice
T254 545-549 IN denotes with
T255 550-553 DT denotes the
T257 554-562 VBN denotes targeted
T256 563-573 NN denotes disruption
T258 574-576 IN denotes of
T259 577-583 NN denotes alphaA
T261 583-584 HYPH denotes -
T262 585-588 CC denotes and
T263 589-595 NN denotes alphaB
T264 595-596 HYPH denotes -
T260 596-606 NN denotes crystallin
T265 607-612 NNS denotes genes
T266 613-614 -LRB- denotes (
T267 614-620 NN denotes alphaA
T269 620-621 HYPH denotes /
T268 621-624 NN denotes BKO
T270 624-625 -RRB- denotes )
T271 625-626 . denotes .
R100 T241 T239 prep of,purpose
R101 T242 T243 det this,study
R102 T243 T241 pobj study,of
R103 T244 T245 aux to,characterize
R104 T245 T240 xcomp characterize,was
R105 T246 T247 amod gross,morphology
R106 T247 T245 dobj morphology,characterize
R107 T248 T247 amod lenticular,morphology
R108 T249 T245 prep in,characterize
R109 T250 T251 amod normal,mice
R110 T251 T249 pobj mice,in
R111 T252 T251 cc and,mice
R112 T253 T251 conj mice,mice
R113 T254 T253 prep with,mice
R114 T255 T256 det the,disruption
R115 T256 T254 pobj disruption,with
R116 T257 T256 amod targeted,disruption
R117 T258 T256 prep of,disruption
R118 T259 T260 nmod alphaA,crystallin
R119 T260 T265 compound crystallin,genes
R120 T261 T259 punct -,alphaA
R121 T262 T259 cc and,alphaA
R122 T263 T259 conj alphaB,alphaA
R123 T264 T260 punct -,crystallin
R124 T265 T258 pobj genes,of
R125 T266 T265 punct (,genes
R126 T267 T268 compound alphaA,BKO
R127 T268 T265 parataxis BKO,genes
R128 T269 T268 punct /,BKO
R129 T270 T268 punct ),BKO
R130 T271 T240 punct .,was
R20 T156 T157 nummod One,approach
R21 T157 T158 nsubj approach,is
R22 T159 T157 prep to,approach
R23 T160 T159 pcomp resolving,to
R24 T161 T160 dobj some,resolving
R25 T162 T161 prep of,some
R26 T163 T164 det the,functions
R27 T164 T162 pobj functions,of
R28 T165 T166 advmod in,vivo
R29 T166 T164 amod vivo,functions
R30 T167 T164 prep of,functions
R31 T168 T169 compound alpha,crystallin
R32 T169 T167 pobj crystallin,of
R33 T170 T169 punct -,crystallin
R34 T171 T172 aux to,generate
R35 T172 T158 xcomp generate,is
R36 T173 T174 compound animal,models
R37 T174 T172 dobj models,generate
R38 T175 T176 advmod where,eliminated
R39 T176 T174 relcl eliminated,models
R40 T177 T176 nsubjpass one,eliminated
R41 T178 T177 cc or,one
R42 T179 T177 conj both,one
R43 T180 T177 prep of,one
R44 T181 T182 det the,products
R45 T182 T180 pobj products,of
R46 T183 T184 compound alpha,crystallin
R47 T184 T182 compound crystallin,products
R48 T185 T184 punct -,crystallin
R49 T186 T182 compound gene,products
R50 T187 T176 aux have,eliminated
R51 T188 T176 auxpass been,eliminated
R52 T189 T158 punct .,is
R53 T191 T192 prep In,compensate
R54 T193 T194 det the,mice
R55 T194 T191 pobj mice,In
R56 T195 T196 amod single,knockout
R57 T196 T194 compound knockout,mice
R58 T197 T198 compound alpha,crystallin
R59 T198 T196 compound crystallin,knockout
R60 T199 T198 punct -,crystallin
R61 T200 T192 punct ", ",compensate
R62 T201 T202 det the,crystallin
R63 T202 T192 nsubj crystallin,compensate
R64 T203 T202 amod remaining,crystallin
R65 T204 T202 compound alpha,crystallin
R66 T205 T202 punct -,crystallin
R67 T206 T192 aux may,compensate
R68 T207 T192 advmod fully,compensate
R69 T208 T207 cc or,fully
R70 T209 T207 conj partially,fully
R71 T210 T192 prep for,compensate
R72 T211 T210 pobj some,for
R73 T212 T211 prep of,some
R74 T213 T214 det the,functions
R75 T214 T212 pobj functions,of
R76 T215 T214 prep of,functions
R77 T216 T217 det the,protein
R78 T217 T215 pobj protein,of
R79 T218 T217 amod missing,protein
R80 T219 T192 punct ", ",compensate
R81 T220 T221 advmod especially,in
R82 T221 T192 prep in,compensate
R83 T222 T223 det the,lens
R84 T223 T221 pobj lens,in
R85 T224 T223 punct ", ",lens
R86 T225 T226 advmod where,expressed
R87 T226 T223 relcl expressed,lens
R88 T227 T228 preconj both,alphaA
R89 T228 T226 nsubjpass alphaA,expressed
R90 T229 T228 cc and,alphaA
R91 T230 T228 conj alphaB,alphaA
R92 T231 T226 auxpass are,expressed
R93 T232 T226 advmod normally,expressed
R94 T233 T226 prep at,expressed
R95 T234 T235 amod high,levels
R96 T235 T233 pobj levels,at
R97 T236 T192 punct .,compensate
R98 T238 T239 det The,purpose
R99 T239 T240 nsubj purpose,was