craft-sa-dev Home  

PMC:1440874 / 38932-40145 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T8529 0-9 JJ denotes Embryonic
T8530 10-19 NN denotes lethality
T8532 20-22 IN denotes in
T8533 23-27 NNS denotes mice
T8534 28-30 IN denotes in
T8535 31-34 DT denotes the
T8536 35-42 NN denotes absence
T8537 43-45 IN denotes of
T8538 46-50 NN denotes Atrx
T8531 51-54 VBD denotes was
T8539 55-56 DT denotes a
T8541 57-67 JJ denotes surprising
T8540 68-75 NN denotes finding
T8542 75-77 , denotes ,
T8543 77-79 IN denotes as
T8545 80-85 EX denotes there
T8546 86-89 VBD denotes had
T8544 90-94 VBN denotes been
T8547 95-97 DT denotes no
T8548 98-108 NN denotes suggestion
T8549 109-111 IN denotes of
T8550 112-118 JJ denotes foetal
T8551 119-123 NN denotes loss
T8552 124-126 IN denotes in
T8553 127-130 DT denotes the
T8555 131-136 JJ denotes human
T8556 137-140 NN denotes ATR
T8558 140-141 HYPH denotes -
T8557 141-142 NN denotes X
T8554 143-151 NN denotes syndrome
T8559 151-152 . denotes .
T8560 152-296 sentence denotes It is possible that the role of Atrx in the trophoblast is specific to mice and that ATRX has no role or is redundant in the human trophoblast.
T8561 153-155 PRP denotes It
T8562 156-158 VBZ denotes is
T8563 159-167 JJ denotes possible
T8564 168-172 IN denotes that
T8566 173-176 DT denotes the
T8567 177-181 NN denotes role
T8568 182-184 IN denotes of
T8569 185-189 NN denotes Atrx
T8570 190-192 IN denotes in
T8571 193-196 DT denotes the
T8572 197-208 NN denotes trophoblast
T8565 209-211 VBZ denotes is
T8573 212-220 JJ denotes specific
T8574 221-223 IN denotes to
T8575 224-228 NNS denotes mice
T8576 229-232 CC denotes and
T8577 233-237 IN denotes that
T8579 238-242 NN denotes ATRX
T8578 243-246 VBZ denotes has
T8580 247-249 DT denotes no
T8581 250-254 NN denotes role
T8582 255-257 CC denotes or
T8583 258-260 VBZ denotes is
T8584 261-270 JJ denotes redundant
T8585 271-273 IN denotes in
T8586 274-277 DT denotes the
T8588 278-283 JJ denotes human
T8587 284-295 NN denotes trophoblast
T8589 295-296 . denotes .
T8590 296-370 sentence denotes Indeed, the birth weight of babies with ATR-X syndrome is usually normal.
T8591 297-303 RB denotes Indeed
T8593 303-305 , denotes ,
T8594 305-308 DT denotes the
T8596 309-314 NN denotes birth
T8595 315-321 NN denotes weight
T8597 322-324 IN denotes of
T8598 325-331 NNS denotes babies
T8599 332-336 IN denotes with
T8600 337-340 NN denotes ATR
T8602 340-341 HYPH denotes -
T8601 341-342 NN denotes X
T8603 343-351 NN denotes syndrome
T8592 352-354 VBZ denotes is
T8604 355-362 RB denotes usually
T8605 363-369 JJ denotes normal
T8606 369-370 . denotes .
T8607 370-577 sentence denotes An alternative explanation for the unexpectedly severe phenotype we observed in mice is that the Atrx Δ18Δneo deletion generated by Cre recombination completely ablates full-length Atrx protein (Figure 2E).
T8608 371-373 DT denotes An
T8610 374-385 JJ denotes alternative
T8609 386-397 NN denotes explanation
T8612 398-401 IN denotes for
T8613 402-405 DT denotes the
T8615 406-418 RB denotes unexpectedly
T8616 419-425 JJ denotes severe
T8614 426-435 NN denotes phenotype
T8617 436-438 PRP denotes we
T8618 439-447 VBD denotes observed
T8619 448-450 IN denotes in
T8620 451-455 NNS denotes mice
T8611 456-458 VBZ denotes is
T8621 459-463 IN denotes that
T8623 464-467 DT denotes the
T8625 468-480 NN denotes Atrx Δ18Δneo
T8624 481-489 NN denotes deletion
T8626 490-499 VBN denotes generated
T8627 500-502 IN denotes by
T8628 503-506 NN denotes Cre
T8629 507-520 NN denotes recombination
T8630 521-531 RB denotes completely
T8622 532-539 VBZ denotes ablates
T8631 540-544 JJ denotes full
T8633 544-545 HYPH denotes -
T8632 545-551 NN denotes length
T8635 552-556 NN denotes Atrx
T8634 557-564 NN denotes protein
T8636 565-566 -LRB- denotes (
T8638 566-572 NN denotes Figure
T8637 573-575 NN denotes 2E
T8639 575-576 -RRB- denotes )
T8640 576-577 . denotes .
T8641 577-703 sentence denotes In contrast, all disease-causing mutations characterised in human ATR-X pedigrees appear to give rise to hypomorphic alleles.
T8642 578-580 IN denotes In
T8644 581-589 NN denotes contrast
T8645 589-591 , denotes ,
T8646 591-594 DT denotes all
T8648 595-602 NN denotes disease
T8650 602-603 HYPH denotes -
T8649 603-610 VBG denotes causing
T8647 611-620 NNS denotes mutations
T8651 621-634 VBN denotes characterised
T8652 635-637 IN denotes in
T8653 638-643 JJ denotes human
T8655 644-647 NN denotes ATR
T8657 647-648 HYPH denotes -
T8656 648-649 NN denotes X
T8654 650-659 NNS denotes pedigrees
T8643 660-666 VBP denotes appear
T8658 667-669 TO denotes to
T8659 670-674 VB denotes give
T8660 675-679 NN denotes rise
T8661 680-682 IN denotes to
T8662 683-694 JJ denotes hypomorphic
T8663 695-702 NNS denotes alleles
T8664 702-703 . denotes .
T8665 703-1023 sentence denotes Some full-length ATRX protein is detected in cases predicted to have truncating mutations (RJG, unpublished data), and residual ATPase activity in ATRX immunoprecipitates can be detected in Epstein-Barr virus-transformed lymphocytes of all human patients analysed to date (A. Argentaro and M. Mitson, unpublished data).
T8666 704-708 DT denotes Some
T8668 709-713 JJ denotes full
T8670 713-714 HYPH denotes -
T8669 714-720 NN denotes length
T8671 721-725 NN denotes ATRX
T8667 726-733 NN denotes protein
T8673 734-736 VBZ denotes is
T8672 737-745 VBN denotes detected
T8674 746-748 IN denotes in
T8675 749-754 NNS denotes cases
T8676 755-764 VBN denotes predicted
T8677 765-767 TO denotes to
T8678 768-772 VB denotes have
T8679 773-783 NN denotes truncating
T8680 784-793 NNS denotes mutations
T8681 794-795 -LRB- denotes (
T8683 795-798 NN denotes RJG
T8684 798-800 , denotes ,
T8685 800-811 JJ denotes unpublished
T8682 812-816 NNS denotes data
T8686 816-817 -RRB- denotes )
T8687 817-819 , denotes ,
T8688 819-822 CC denotes and
T8689 823-831 JJ denotes residual
T8691 832-838 NN denotes ATPase
T8690 839-847 NN denotes activity
T8693 848-850 IN denotes in
T8694 851-855 NN denotes ATRX
T8695 856-874 NNS denotes immunoprecipitates
T8696 875-878 MD denotes can
T8697 879-881 VB denotes be
T8692 882-890 VBN denotes detected
T8698 891-893 IN denotes in
T8699 894-901 NN denotes Epstein
T8701 901-902 HYPH denotes -
T8700 902-906 NN denotes Barr
T8702 907-912 NN denotes virus
T8704 912-913 HYPH denotes -
T8703 913-924 VBN denotes transformed
T8705 925-936 NNS denotes lymphocytes
T8706 937-939 IN denotes of
T8707 940-943 DT denotes all
T8709 944-949 JJ denotes human
T8708 950-958 NNS denotes patients
T8710 959-967 VBN denotes analysed
T8711 968-970 IN denotes to
T8712 971-975 NN denotes date
T8713 976-977 -LRB- denotes (
T8714 977-979 NNP denotes A.
T8715 980-989 NNP denotes Argentaro
T8716 990-993 CC denotes and
T8717 994-996 NNP denotes M.
T8718 997-1003 NNP denotes Mitson
T8719 1003-1005 , denotes ,
T8720 1005-1016 JJ denotes unpublished
T8721 1017-1021 NNS denotes data
T8722 1021-1022 -RRB- denotes )
T8723 1022-1023 . denotes .
T8724 1023-1213 sentence denotes The failure to observe a truly null ATRX allele among human patients strongly suggests that, as in the mouse, the complete absence of ATRX protein is incompatible with human fetal survival.
T8725 1024-1027 DT denotes The
T8726 1028-1035 NN denotes failure
T8728 1036-1038 TO denotes to
T8729 1039-1046 VB denotes observe
T8730 1047-1048 DT denotes a
T8732 1049-1054 RB denotes truly
T8733 1055-1059 JJ denotes null
T8734 1060-1064 NN denotes ATRX
T8731 1065-1071 NN denotes allele
T8735 1072-1077 IN denotes among
T8736 1078-1083 JJ denotes human
T8737 1084-1092 NNS denotes patients
T8738 1093-1101 RB denotes strongly
T8727 1102-1110 VBZ denotes suggests
T8739 1111-1115 IN denotes that
T8741 1115-1117 , denotes ,
T8742 1117-1119 IN denotes as
T8743 1120-1122 IN denotes in
T8744 1123-1126 DT denotes the
T8745 1127-1132 NN denotes mouse
T8746 1132-1134 , denotes ,
T8747 1134-1137 DT denotes the
T8749 1138-1146 JJ denotes complete
T8748 1147-1154 NN denotes absence
T8750 1155-1157 IN denotes of
T8751 1158-1162 NN denotes ATRX
T8752 1163-1170 NN denotes protein
T8740 1171-1173 VBZ denotes is
T8753 1174-1186 JJ denotes incompatible
T8754 1187-1191 IN denotes with
T8755 1192-1197 JJ denotes human
T8757 1198-1203 JJ denotes fetal
T8756 1204-1212 NN denotes survival
T8758 1212-1213 . denotes .
R5016 T8529 T8530 amod Embryonic,lethality
R5017 T8530 T8531 nsubj lethality,was
R5018 T8532 T8530 prep in,lethality
R5019 T8533 T8532 pobj mice,in
R5020 T8534 T8530 prep in,lethality
R5021 T8535 T8536 det the,absence
R5022 T8536 T8534 pobj absence,in
R5023 T8537 T8536 prep of,absence
R5024 T8538 T8537 pobj Atrx,of
R5025 T8539 T8540 det a,finding
R5026 T8540 T8531 attr finding,was
R5027 T8541 T8540 amod surprising,finding
R5028 T8542 T8531 punct ", ",was
R5029 T8543 T8544 mark as,been
R5030 T8544 T8531 advcl been,was
R5031 T8545 T8544 expl there,been
R5032 T8546 T8544 aux had,been
R5033 T8547 T8548 det no,suggestion
R5034 T8548 T8544 attr suggestion,been
R5035 T8549 T8548 prep of,suggestion
R5036 T8550 T8551 amod foetal,loss
R5037 T8551 T8549 pobj loss,of
R5038 T8552 T8544 prep in,been
R5039 T8553 T8554 det the,syndrome
R5040 T8554 T8552 pobj syndrome,in
R5041 T8555 T8554 amod human,syndrome
R5042 T8556 T8557 compound ATR,X
R5043 T8557 T8554 compound X,syndrome
R5044 T8558 T8557 punct -,X
R5045 T8559 T8531 punct .,was
R5046 T8561 T8562 nsubj It,is
R5047 T8563 T8562 acomp possible,is
R5048 T8564 T8565 mark that,is
R5049 T8565 T8562 advcl is,is
R5050 T8566 T8567 det the,role
R5051 T8567 T8565 nsubj role,is
R5052 T8568 T8567 prep of,role
R5053 T8569 T8568 pobj Atrx,of
R5054 T8570 T8567 prep in,role
R5055 T8571 T8572 det the,trophoblast
R5056 T8572 T8570 pobj trophoblast,in
R5057 T8573 T8565 acomp specific,is
R5058 T8574 T8573 prep to,specific
R5059 T8575 T8574 pobj mice,to
R5060 T8576 T8565 cc and,is
R5061 T8577 T8578 mark that,has
R5062 T8578 T8565 conj has,is
R5063 T8579 T8578 nsubj ATRX,has
R5064 T8580 T8581 det no,role
R5065 T8581 T8578 dobj role,has
R5066 T8582 T8578 cc or,has
R5067 T8583 T8578 conj is,has
R5068 T8584 T8583 acomp redundant,is
R5069 T8585 T8578 prep in,has
R5070 T8586 T8587 det the,trophoblast
R5071 T8587 T8585 pobj trophoblast,in
R5072 T8588 T8587 amod human,trophoblast
R5073 T8589 T8562 punct .,is
R5074 T8591 T8592 advmod Indeed,is
R5075 T8593 T8592 punct ", ",is
R5076 T8594 T8595 det the,weight
R5077 T8595 T8592 nsubj weight,is
R5078 T8596 T8595 compound birth,weight
R5079 T8597 T8595 prep of,weight
R5080 T8598 T8597 pobj babies,of
R5081 T8599 T8598 prep with,babies
R5082 T8600 T8601 compound ATR,X
R5083 T8601 T8603 compound X,syndrome
R5084 T8602 T8601 punct -,X
R5085 T8603 T8599 pobj syndrome,with
R5086 T8604 T8592 advmod usually,is
R5087 T8605 T8592 acomp normal,is
R5088 T8606 T8592 punct .,is
R5089 T8608 T8609 det An,explanation
R5090 T8609 T8611 nsubj explanation,is
R5091 T8610 T8609 amod alternative,explanation
R5092 T8612 T8609 prep for,explanation
R5093 T8613 T8614 det the,phenotype
R5094 T8614 T8612 pobj phenotype,for
R5095 T8615 T8616 advmod unexpectedly,severe
R5096 T8616 T8614 amod severe,phenotype
R5097 T8617 T8618 nsubj we,observed
R5098 T8618 T8614 advcl observed,phenotype
R5099 T8619 T8618 prep in,observed
R5100 T8620 T8619 pobj mice,in
R5101 T8621 T8622 mark that,ablates
R5102 T8622 T8611 ccomp ablates,is
R5103 T8623 T8624 det the,deletion
R5104 T8624 T8622 nsubj deletion,ablates
R5105 T8625 T8624 compound Atrx Δ18Δneo,deletion
R5106 T8626 T8624 acl generated,deletion
R5107 T8627 T8626 prep by,generated
R5108 T8628 T8629 compound Cre,recombination
R5109 T8629 T8627 pobj recombination,by
R5110 T8630 T8622 advmod completely,ablates
R5111 T8631 T8632 amod full,length
R5112 T8632 T8634 compound length,protein
R5113 T8633 T8632 punct -,length
R5114 T8634 T8622 dobj protein,ablates
R5115 T8635 T8634 compound Atrx,protein
R5116 T8636 T8637 punct (,2E
R5117 T8637 T8611 parataxis 2E,is
R5118 T8638 T8637 compound Figure,2E
R5119 T8639 T8637 punct ),2E
R5120 T8640 T8611 punct .,is
R5121 T8642 T8643 prep In,appear
R5122 T8644 T8642 pobj contrast,In
R5123 T8645 T8643 punct ", ",appear
R5124 T8646 T8647 det all,mutations
R5125 T8647 T8643 nsubj mutations,appear
R5126 T8648 T8649 npadvmod disease,causing
R5127 T8649 T8647 amod causing,mutations
R5128 T8650 T8649 punct -,causing
R5129 T8651 T8647 acl characterised,mutations
R5130 T8652 T8651 prep in,characterised
R5131 T8653 T8654 amod human,pedigrees
R5132 T8654 T8652 pobj pedigrees,in
R5133 T8655 T8656 compound ATR,X
R5134 T8656 T8654 compound X,pedigrees
R5135 T8657 T8656 punct -,X
R5136 T8658 T8659 aux to,give
R5137 T8659 T8643 xcomp give,appear
R5138 T8660 T8659 dobj rise,give
R5139 T8661 T8659 prep to,give
R5140 T8662 T8663 amod hypomorphic,alleles
R5141 T8663 T8661 pobj alleles,to
R5142 T8664 T8643 punct .,appear
R5143 T8666 T8667 det Some,protein
R5144 T8667 T8672 nsubjpass protein,detected
R5145 T8668 T8669 amod full,length
R5146 T8669 T8667 compound length,protein
R5147 T8670 T8669 punct -,length
R5148 T8671 T8667 compound ATRX,protein
R5149 T8673 T8672 auxpass is,detected
R5150 T8674 T8672 prep in,detected
R5151 T8675 T8674 pobj cases,in
R5152 T8676 T8675 acl predicted,cases
R5153 T8677 T8678 aux to,have
R5154 T8678 T8676 xcomp have,predicted
R5155 T8679 T8680 compound truncating,mutations
R5156 T8680 T8678 dobj mutations,have
R5157 T8681 T8682 punct (,data
R5158 T8682 T8672 parataxis data,detected
R5159 T8683 T8682 dep RJG,data
R5160 T8684 T8682 punct ", ",data
R5161 T8685 T8682 amod unpublished,data
R5162 T8686 T8682 punct ),data
R5163 T8687 T8672 punct ", ",detected
R5164 T8688 T8672 cc and,detected
R5165 T8689 T8690 amod residual,activity
R5166 T8690 T8692 nsubjpass activity,detected
R5167 T8691 T8690 compound ATPase,activity
R5168 T8692 T8672 conj detected,detected
R5169 T8693 T8690 prep in,activity
R5170 T8694 T8695 compound ATRX,immunoprecipitates
R5171 T8695 T8693 pobj immunoprecipitates,in
R5172 T8696 T8692 aux can,detected
R5173 T8697 T8692 auxpass be,detected
R5174 T8698 T8692 prep in,detected
R5175 T8699 T8700 compound Epstein,Barr
R5176 T8700 T8702 compound Barr,virus
R5177 T8701 T8700 punct -,Barr
R5178 T8702 T8703 npadvmod virus,transformed
R5179 T8703 T8705 amod transformed,lymphocytes
R5180 T8704 T8703 punct -,transformed
R5181 T8705 T8698 pobj lymphocytes,in
R5182 T8706 T8705 prep of,lymphocytes
R5183 T8707 T8708 det all,patients
R5184 T8708 T8706 pobj patients,of
R5185 T8709 T8708 amod human,patients
R5186 T8710 T8708 acl analysed,patients
R5187 T8711 T8710 prep to,analysed
R5188 T8712 T8711 pobj date,to
R5189 T8713 T8714 punct (,A.
R5190 T8714 T8692 meta A.,detected
R5191 T8715 T8714 nmod Argentaro,A.
R5192 T8716 T8714 cc and,A.
R5193 T8717 T8714 conj M.,A.
R5194 T8718 T8717 nmod Mitson,M.
R5195 T8719 T8717 punct ", ",M.
R5196 T8720 T8721 amod unpublished,data
R5197 T8721 T8717 conj data,M.
R5198 T8722 T8721 punct ),data
R5199 T8723 T8692 punct .,detected
R5200 T8725 T8726 det The,failure
R5201 T8726 T8727 nsubj failure,suggests
R5202 T8728 T8729 aux to,observe
R5203 T8729 T8726 acl observe,failure
R5204 T8730 T8731 det a,allele
R5205 T8731 T8729 dobj allele,observe
R5206 T8732 T8733 advmod truly,null
R5207 T8733 T8731 amod null,allele
R5208 T8734 T8731 compound ATRX,allele
R5209 T8735 T8729 prep among,observe
R5210 T8736 T8737 amod human,patients
R5211 T8737 T8735 pobj patients,among
R5212 T8738 T8727 advmod strongly,suggests
R5213 T8739 T8740 mark that,is
R5214 T8740 T8727 ccomp is,suggests
R5215 T8741 T8740 punct ", ",is
R5216 T8742 T8740 prep as,is
R5217 T8743 T8742 prep in,as
R5218 T8744 T8745 det the,mouse
R5219 T8745 T8743 pobj mouse,in
R5220 T8746 T8740 punct ", ",is
R5221 T8747 T8748 det the,absence
R5222 T8748 T8740 nsubj absence,is
R5223 T8749 T8748 amod complete,absence
R5224 T8750 T8748 prep of,absence
R5225 T8751 T8752 compound ATRX,protein
R5226 T8752 T8750 pobj protein,of
R5227 T8753 T8740 acomp incompatible,is
R5228 T8754 T8753 prep with,incompatible
R5229 T8755 T8756 amod human,survival
R5230 T8756 T8754 pobj survival,with
R5231 T8757 T8756 amod fetal,survival
R5232 T8758 T8727 punct .,suggests