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PMC:1064854 / 14412-16053 JSONTXT 6 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T9829 0-7 JJ denotes General
T9831 8-18 JJ denotes histologic
T9830 19-27 NNS denotes analyses
T9833 28-32 VBD denotes were
T9832 33-42 VBN denotes performed
T9834 43-45 TO denotes to
T9835 46-51 VB denotes begin
T9836 52-54 TO denotes to
T9837 55-63 VB denotes evaluate
T9838 64-67 DT denotes the
T9840 68-72 JJ denotes mild
T9841 73-79 NN denotes growth
T9839 80-86 NN denotes defect
T9842 87-92 VBN denotes found
T9843 93-95 IN denotes in
T9844 96-105 JJ denotes postnatal
T9845 106-111 NN denotes heart
T9846 112-115 CC denotes and
T9847 116-124 JJ denotes skeletal
T9848 125-131 NN denotes muscle
T9849 132-134 IN denotes of
T9850 135-138 DT denotes the
T9852 139-142 NN denotes PGC
T9854 142-143 HYPH denotes -
T9853 143-145 NN denotes 1α
T9855 145-146 SYM denotes −
T9856 146-147 HYPH denotes /
T9857 147-148 SYM denotes −
T9851 149-153 NNS denotes mice
T9858 153-154 . denotes .
T9859 154-305 sentence denotes There were no obvious abnormalities in cellularity, cell size, or extracellular matrix in the tissues of 1–2-mo-old PGC-1α−/− mice (unpublished data).
T9860 155-160 EX denotes There
T9861 161-165 VBD denotes were
T9862 166-168 DT denotes no
T9864 169-176 JJ denotes obvious
T9863 177-190 NNS denotes abnormalities
T9865 191-193 IN denotes in
T9866 194-205 NN denotes cellularity
T9867 205-207 , denotes ,
T9868 207-211 NN denotes cell
T9869 212-216 NN denotes size
T9870 216-218 , denotes ,
T9871 218-220 CC denotes or
T9872 221-234 JJ denotes extracellular
T9873 235-241 NN denotes matrix
T9874 242-244 IN denotes in
T9875 245-248 DT denotes the
T9876 249-256 NNS denotes tissues
T9877 257-259 IN denotes of
T9878 260-261 CD denotes 1
T9880 261-262 SYM denotes –
T9879 262-263 CD denotes 2
T9882 263-264 HYPH denotes -
T9881 264-266 NN denotes mo
T9884 266-267 HYPH denotes -
T9883 267-270 JJ denotes old
T9886 271-274 NN denotes PGC
T9888 274-275 HYPH denotes -
T9887 275-277 NN denotes 1α
T9889 277-278 SYM denotes −
T9890 278-279 HYPH denotes /
T9891 279-280 SYM denotes −
T9885 281-285 NNS denotes mice
T9892 286-287 -LRB- denotes (
T9894 287-298 JJ denotes unpublished
T9893 299-303 NNS denotes data
T9895 303-304 -RRB- denotes )
T9896 304-305 . denotes .
T9897 305-448 sentence denotes Given the important role of PGC-1α in mitochondrial function and biogenesis, we examined mitochondrial ultrastructure in the relevant tissues.
T9898 306-311 VBN denotes Given
T9900 312-315 DT denotes the
T9902 316-325 JJ denotes important
T9901 326-330 NN denotes role
T9903 331-333 IN denotes of
T9904 334-337 NN denotes PGC
T9906 337-338 HYPH denotes -
T9905 338-340 NN denotes 1α
T9907 341-343 IN denotes in
T9908 344-357 JJ denotes mitochondrial
T9909 358-366 NN denotes function
T9910 367-370 CC denotes and
T9911 371-381 NN denotes biogenesis
T9912 381-383 , denotes ,
T9913 383-385 PRP denotes we
T9899 386-394 VBD denotes examined
T9914 395-408 JJ denotes mitochondrial
T9915 409-423 NN denotes ultrastructure
T9916 424-426 IN denotes in
T9917 427-430 DT denotes the
T9919 431-439 JJ denotes relevant
T9918 440-447 NNS denotes tissues
T9920 447-448 . denotes .
T9921 448-619 sentence denotes Electron microscopic analysis revealed fewer and smaller mitochondria in soleus muscle of PGC-1α−/− mice compared to sex- and age- matched PGC-1α+/+ controls (Figure 3A).
T9922 449-457 NN denotes Electron
T9923 458-469 JJ denotes microscopic
T9924 470-478 NN denotes analysis
T9925 479-487 VBD denotes revealed
T9926 488-493 JJR denotes fewer
T9928 494-497 CC denotes and
T9929 498-505 JJR denotes smaller
T9927 506-518 NNS denotes mitochondria
T9930 519-521 IN denotes in
T9931 522-528 NN denotes soleus
T9932 529-535 NN denotes muscle
T9933 536-538 IN denotes of
T9934 539-542 NN denotes PGC
T9936 542-543 HYPH denotes -
T9935 543-545 NN denotes 1α
T9938 545-546 SYM denotes −
T9939 546-547 HYPH denotes /
T9940 547-548 SYM denotes −
T9937 549-553 NNS denotes mice
T9941 554-562 VBN denotes compared
T9942 563-565 IN denotes to
T9943 566-569 NN denotes sex
T9945 569-570 HYPH denotes -
T9946 571-574 CC denotes and
T9947 575-578 NN denotes age
T9948 578-579 HYPH denotes -
T9944 580-587 VBN denotes matched
T9950 588-591 NN denotes PGC
T9952 591-592 HYPH denotes -
T9951 592-594 NN denotes 1α
T9953 594-595 SYM denotes +
T9954 595-596 HYPH denotes /
T9955 596-597 SYM denotes +
T9949 598-606 NNS denotes controls
T9956 607-608 -LRB- denotes (
T9958 608-614 NN denotes Figure
T9957 615-617 NN denotes 3A
T9959 617-618 -RRB- denotes )
T9960 618-619 . denotes .
T9961 619-877 sentence denotes Quantitative morphometry of the electron micrographs confirmed that the cellular volume density of soleus mitochondria was significantly lower in PGC-1α−/− mice compared to PGC-1α+/+ controls independent of changes in the myofibrillar component (Figure 3B).
T9962 620-632 JJ denotes Quantitative
T9963 633-644 NN denotes morphometry
T9965 645-647 IN denotes of
T9966 648-651 DT denotes the
T9968 652-660 NN denotes electron
T9967 661-672 NNS denotes micrographs
T9964 673-682 VBD denotes confirmed
T9969 683-687 IN denotes that
T9971 688-691 DT denotes the
T9973 692-700 JJ denotes cellular
T9974 701-707 NN denotes volume
T9972 708-715 NN denotes density
T9975 716-718 IN denotes of
T9976 719-725 NN denotes soleus
T9977 726-738 NNS denotes mitochondria
T9970 739-742 VBD denotes was
T9978 743-756 RB denotes significantly
T9979 757-762 JJR denotes lower
T9980 763-765 IN denotes in
T9981 766-769 NN denotes PGC
T9983 769-770 HYPH denotes -
T9982 770-772 NN denotes 1α
T9985 772-773 SYM denotes −
T9986 773-774 HYPH denotes /
T9987 774-775 SYM denotes −
T9984 776-780 NNS denotes mice
T9988 781-789 VBN denotes compared
T9989 790-792 IN denotes to
T9990 793-796 NN denotes PGC
T9992 796-797 HYPH denotes -
T9991 797-799 NN denotes 1α
T9994 799-800 SYM denotes +
T9995 800-801 HYPH denotes /
T9996 801-802 SYM denotes +
T9993 803-811 NNS denotes controls
T9997 812-823 JJ denotes independent
T9998 824-826 IN denotes of
T9999 827-834 NNS denotes changes
T10000 835-837 IN denotes in
T10001 838-841 DT denotes the
T10003 842-854 JJ denotes myofibrillar
T10002 855-864 NN denotes component
T10004 865-866 -LRB- denotes (
T10006 866-872 NN denotes Figure
T10005 873-875 NN denotes 3B
T10007 875-876 -RRB- denotes )
T10008 876-877 . denotes .
T10009 877-1221 sentence denotes Consistent with a defect in mitochondrial biogenesis, we found a reduction in the expression of nuclear genes encoding proteins involved in mitochondrial electron transport (cytochrome c and cytochrome oxidase IV) and oxidative phosphorylation (beta subunit of ATP synthase) in soleus muscle of PGC-1α−/− mice compared with PGC-1α+/+ controls.
T10010 878-888 JJ denotes Consistent
T10012 889-893 IN denotes with
T10013 894-895 DT denotes a
T10014 896-902 NN denotes defect
T10015 903-905 IN denotes in
T10016 906-919 JJ denotes mitochondrial
T10017 920-930 NN denotes biogenesis
T10018 930-932 , denotes ,
T10019 932-934 PRP denotes we
T10011 935-940 VBD denotes found
T10020 941-942 DT denotes a
T10021 943-952 NN denotes reduction
T10022 953-955 IN denotes in
T10023 956-959 DT denotes the
T10024 960-970 NN denotes expression
T10025 971-973 IN denotes of
T10026 974-981 JJ denotes nuclear
T10027 982-987 NNS denotes genes
T10028 988-996 VBG denotes encoding
T10029 997-1005 NN denotes proteins
T10030 1006-1014 VBN denotes involved
T10031 1015-1017 IN denotes in
T10032 1018-1031 JJ denotes mitochondrial
T10034 1032-1040 NN denotes electron
T10033 1041-1050 NN denotes transport
T10035 1051-1052 -LRB- denotes (
T10036 1052-1062 NN denotes cytochrome
T10037 1063-1064 NN denotes c
T10038 1065-1068 CC denotes and
T10039 1069-1079 NN denotes cytochrome
T10040 1080-1087 NN denotes oxidase
T10041 1088-1090 CD denotes IV
T10042 1090-1091 -RRB- denotes )
T10043 1092-1095 CC denotes and
T10044 1096-1105 JJ denotes oxidative
T10045 1106-1121 NN denotes phosphorylation
T10046 1122-1123 -LRB- denotes (
T10047 1123-1127 NN denotes beta
T10048 1128-1135 NN denotes subunit
T10049 1136-1138 IN denotes of
T10050 1139-1142 NN denotes ATP
T10051 1143-1151 NN denotes synthase
T10052 1151-1152 -RRB- denotes )
T10053 1153-1155 IN denotes in
T10054 1156-1162 NN denotes soleus
T10055 1163-1169 NN denotes muscle
T10056 1170-1172 IN denotes of
T10057 1173-1176 NN denotes PGC
T10059 1176-1177 HYPH denotes -
T10058 1177-1179 NN denotes 1α
T10061 1179-1180 SYM denotes −
T10062 1180-1181 HYPH denotes /
T10063 1181-1182 SYM denotes −
T10060 1183-1187 NNS denotes mice
T10064 1188-1196 VBN denotes compared
T10065 1197-1201 IN denotes with
T10066 1202-1205 NN denotes PGC
T10068 1205-1206 HYPH denotes -
T10067 1206-1208 NN denotes 1α
T10070 1208-1209 SYM denotes +
T10071 1209-1210 HYPH denotes /
T10072 1210-1211 SYM denotes +
T10069 1212-1220 NNS denotes controls
T10073 1220-1221 . denotes .
T10074 1221-1459 sentence denotes In addition, the expression of Tfam, a known PGC-1α target involved in mitochondrial DNA replication/transcription, was diminished in PGC-1α−/− soleus, providing one potential mechanism for defective mitochondrial biogenesis (Figure 3C).
T10075 1222-1224 IN denotes In
T10077 1225-1233 NN denotes addition
T10078 1233-1235 , denotes ,
T10079 1235-1238 DT denotes the
T10080 1239-1249 NN denotes expression
T10081 1250-1252 IN denotes of
T10082 1253-1257 NN denotes Tfam
T10083 1257-1259 , denotes ,
T10084 1259-1260 DT denotes a
T10086 1261-1266 JJ denotes known
T10087 1267-1270 NN denotes PGC
T10089 1270-1271 HYPH denotes -
T10088 1271-1273 NN denotes 1α
T10085 1274-1280 NN denotes target
T10090 1281-1289 VBN denotes involved
T10091 1290-1292 IN denotes in
T10092 1293-1306 JJ denotes mitochondrial
T10094 1307-1310 NN denotes DNA
T10095 1311-1322 NN denotes replication
T10096 1322-1323 HYPH denotes /
T10093 1323-1336 NN denotes transcription
T10097 1336-1338 , denotes ,
T10098 1338-1341 VBD denotes was
T10076 1342-1352 VBN denotes diminished
T10099 1353-1355 IN denotes in
T10100 1356-1359 NN denotes PGC
T10102 1359-1360 HYPH denotes -
T10101 1360-1362 NN denotes 1α
T10104 1362-1363 SYM denotes −
T10105 1363-1364 HYPH denotes /
T10106 1364-1365 SYM denotes −
T10103 1366-1372 NN denotes soleus
T10107 1372-1374 , denotes ,
T10108 1374-1383 VBG denotes providing
T10109 1384-1387 CD denotes one
T10111 1388-1397 JJ denotes potential
T10110 1398-1407 NN denotes mechanism
T10112 1408-1411 IN denotes for
T10113 1412-1421 JJ denotes defective
T10115 1422-1435 JJ denotes mitochondrial
T10114 1436-1446 NN denotes biogenesis
T10116 1447-1448 -LRB- denotes (
T10118 1448-1454 NN denotes Figure
T10117 1455-1457 NN denotes 3C
T10119 1457-1458 -RRB- denotes )
T10120 1458-1459 . denotes .
T10121 1459-1641 sentence denotes In contrast to the results with soleus, no significant differences in mitochondrial ultrastructure or volume density were noted in heart or BAT of PGC-1α−/− mice (unpublished data).
T10122 1460-1462 IN denotes In
T10124 1463-1471 NN denotes contrast
T10125 1472-1474 IN denotes to
T10126 1475-1478 DT denotes the
T10127 1479-1486 NNS denotes results
T10128 1487-1491 IN denotes with
T10129 1492-1498 NN denotes soleus
T10130 1498-1500 , denotes ,
T10131 1500-1502 DT denotes no
T10133 1503-1514 JJ denotes significant
T10132 1515-1526 NNS denotes differences
T10134 1527-1529 IN denotes in
T10135 1530-1543 JJ denotes mitochondrial
T10136 1544-1558 NN denotes ultrastructure
T10137 1559-1561 CC denotes or
T10138 1562-1568 NN denotes volume
T10139 1569-1576 NN denotes density
T10140 1577-1581 VBD denotes were
T10123 1582-1587 VBN denotes noted
T10141 1588-1590 IN denotes in
T10142 1591-1596 NN denotes heart
T10143 1597-1599 CC denotes or
T10144 1600-1603 NN denotes BAT
T10145 1604-1606 IN denotes of
T10146 1607-1610 NN denotes PGC
T10148 1610-1611 HYPH denotes -
T10147 1611-1613 NN denotes 1α
T10150 1613-1614 SYM denotes −
T10151 1614-1615 HYPH denotes /
T10152 1615-1616 SYM denotes −
T10149 1617-1621 NNS denotes mice
T10153 1622-1623 -LRB- denotes (
T10155 1623-1634 JJ denotes unpublished
T10154 1635-1639 NNS denotes data
T10156 1639-1640 -RRB- denotes )
T10157 1640-1641 . denotes .
R2147 T9829 T9830 amod General,analyses
R2148 T9830 T9832 nsubjpass analyses,performed
R2149 T9831 T9830 amod histologic,analyses
R2150 T9833 T9832 auxpass were,performed
R2151 T9834 T9835 aux to,begin
R2152 T9835 T9832 advcl begin,performed
R2153 T9836 T9837 aux to,evaluate
R2154 T9837 T9835 xcomp evaluate,begin
R2155 T9838 T9839 det the,defect
R2156 T9839 T9837 dobj defect,evaluate
R2157 T9840 T9839 amod mild,defect
R2158 T9841 T9839 compound growth,defect
R2159 T9842 T9839 acl found,defect
R2160 T9843 T9842 prep in,found
R2161 T9844 T9845 amod postnatal,heart
R2162 T9845 T9843 pobj heart,in
R2163 T9846 T9845 cc and,heart
R2164 T9847 T9848 amod skeletal,muscle
R2165 T9848 T9845 conj muscle,heart
R2166 T9849 T9845 prep of,heart
R2167 T9850 T9851 det the,mice
R2168 T9851 T9849 pobj mice,of
R2169 T9852 T9853 nmod PGC,1α
R2170 T9853 T9851 nmod 1α,mice
R2171 T9854 T9853 punct -,1α
R2172 T9855 T9853 punct −,1α
R2173 T9856 T9853 punct /,1α
R2174 T9857 T9853 punct −,1α
R2175 T9858 T9832 punct .,performed
R2176 T9860 T9861 expl There,were
R2177 T9862 T9863 det no,abnormalities
R2178 T9863 T9861 attr abnormalities,were
R2179 T9864 T9863 amod obvious,abnormalities
R2180 T9865 T9863 prep in,abnormalities
R2181 T9866 T9865 pobj cellularity,in
R2182 T9867 T9866 punct ", ",cellularity
R2183 T9868 T9869 compound cell,size
R2184 T9869 T9866 conj size,cellularity
R2185 T9870 T9869 punct ", ",size
R2186 T9871 T9869 cc or,size
R2187 T9872 T9873 amod extracellular,matrix
R2188 T9873 T9869 conj matrix,size
R2189 T9874 T9861 prep in,were
R2190 T9875 T9876 det the,tissues
R2191 T9876 T9874 pobj tissues,in
R2192 T9877 T9876 prep of,tissues
R2193 T9878 T9879 quantmod 1,2
R2194 T9879 T9881 nummod 2,mo
R2195 T9880 T9879 punct –,2
R2196 T9881 T9883 npadvmod mo,old
R2197 T9882 T9881 punct -,mo
R2198 T9883 T9885 amod old,mice
R2199 T9884 T9883 punct -,old
R2200 T9885 T9877 pobj mice,of
R2201 T9886 T9887 nmod PGC,1α
R2202 T9887 T9885 nmod 1α,mice
R2203 T9888 T9887 punct -,1α
R2204 T9889 T9887 punct −,1α
R2205 T9890 T9887 punct /,1α
R2206 T9891 T9887 punct −,1α
R2207 T9892 T9893 punct (,data
R2208 T9893 T9861 meta data,were
R2209 T9894 T9893 amod unpublished,data
R2210 T9895 T9893 punct ),data
R2211 T9896 T9861 punct .,were
R2212 T9898 T9899 prep Given,examined
R2213 T9900 T9901 det the,role
R2214 T9901 T9898 pobj role,Given
R2215 T9902 T9901 amod important,role
R2216 T9903 T9901 prep of,role
R2217 T9904 T9905 compound PGC,1α
R2218 T9905 T9903 pobj 1α,of
R2219 T9906 T9905 punct -,1α
R2220 T9907 T9901 prep in,role
R2221 T9908 T9909 amod mitochondrial,function
R2222 T9909 T9907 pobj function,in
R2223 T9910 T9909 cc and,function
R2224 T9911 T9909 conj biogenesis,function
R2225 T9912 T9899 punct ", ",examined
R2226 T9913 T9899 nsubj we,examined
R2227 T9914 T9915 amod mitochondrial,ultrastructure
R2228 T9915 T9899 dobj ultrastructure,examined
R2229 T9916 T9899 prep in,examined
R2230 T9917 T9918 det the,tissues
R2231 T9918 T9916 pobj tissues,in
R2232 T9919 T9918 amod relevant,tissues
R2233 T9920 T9899 punct .,examined
R2234 T9922 T9923 npadvmod Electron,microscopic
R2235 T9923 T9924 amod microscopic,analysis
R2236 T9924 T9925 nsubj analysis,revealed
R2237 T9926 T9927 amod fewer,mitochondria
R2238 T9927 T9925 dobj mitochondria,revealed
R2239 T9928 T9926 cc and,fewer
R2240 T9929 T9926 conj smaller,fewer
R2241 T9930 T9927 prep in,mitochondria
R2242 T9931 T9932 compound soleus,muscle
R2243 T9932 T9930 pobj muscle,in
R2244 T9933 T9932 prep of,muscle
R2245 T9934 T9935 nmod PGC,1α
R2246 T9935 T9937 nmod 1α,mice
R2247 T9936 T9935 punct -,1α
R2248 T9937 T9933 pobj mice,of
R2249 T9938 T9935 punct −,1α
R2250 T9939 T9935 punct /,1α
R2251 T9940 T9935 punct −,1α
R2252 T9941 T9925 prep compared,revealed
R2253 T9942 T9941 prep to,compared
R2254 T9943 T9944 npadvmod sex,matched
R2255 T9944 T9949 amod matched,controls
R2256 T9945 T9943 punct -,sex
R2257 T9946 T9943 cc and,sex
R2258 T9947 T9943 conj age,sex
R2259 T9948 T9944 punct -,matched
R2260 T9949 T9942 pobj controls,to
R2261 T9950 T9951 nmod PGC,1α
R2262 T9951 T9949 nmod 1α,controls
R2263 T9952 T9951 punct -,1α
R2264 T9953 T9951 punct +,1α
R2265 T9954 T9951 punct /,1α
R2266 T9955 T9951 punct +,1α
R2267 T9956 T9957 punct (,3A
R2268 T9957 T9925 parataxis 3A,revealed
R2269 T9958 T9957 compound Figure,3A
R2270 T9959 T9957 punct ),3A
R2271 T9960 T9925 punct .,revealed
R2272 T9962 T9963 amod Quantitative,morphometry
R2273 T9963 T9964 nsubj morphometry,confirmed
R2274 T9965 T9963 prep of,morphometry
R2275 T9966 T9967 det the,micrographs
R2276 T9967 T9965 pobj micrographs,of
R2277 T9968 T9967 compound electron,micrographs
R2278 T9969 T9970 mark that,was
R2279 T9970 T9964 ccomp was,confirmed
R2280 T9971 T9972 det the,density
R2281 T9972 T9970 nsubj density,was
R2282 T9973 T9972 amod cellular,density
R2283 T9974 T9972 compound volume,density
R2284 T9975 T9972 prep of,density
R2285 T9976 T9977 compound soleus,mitochondria
R2286 T9977 T9975 pobj mitochondria,of
R2287 T9978 T9979 advmod significantly,lower
R2288 T9979 T9970 acomp lower,was
R2289 T9980 T9970 prep in,was
R2290 T9981 T9982 nmod PGC,1α
R2291 T9982 T9984 nmod 1α,mice
R2292 T9983 T9982 punct -,1α
R2293 T9984 T9980 pobj mice,in
R2294 T9985 T9982 punct −,1α
R2295 T9986 T9982 punct /,1α
R2296 T9987 T9982 punct −,1α
R2297 T9988 T9970 prep compared,was
R2298 T9989 T9988 prep to,compared
R2299 T9990 T9991 nmod PGC,1α
R2300 T9991 T9993 nmod 1α,controls
R2301 T9992 T9991 punct -,1α
R2302 T9993 T9989 pobj controls,to
R2303 T9994 T9991 punct +,1α
R2304 T9995 T9991 punct /,1α
R2305 T9996 T9991 punct +,1α
R2306 T9997 T9970 advcl independent,was
R2307 T9998 T9997 prep of,independent
R2308 T9999 T9998 pobj changes,of
R2309 T10000 T9999 prep in,changes
R2310 T10001 T10002 det the,component
R2311 T10002 T10000 pobj component,in
R2312 T10003 T10002 amod myofibrillar,component
R2313 T10004 T10005 punct (,3B
R2314 T10005 T9964 parataxis 3B,confirmed
R2315 T10006 T10005 compound Figure,3B
R2316 T10007 T10005 punct ),3B
R2317 T10008 T9964 punct .,confirmed
R2318 T10010 T10011 advcl Consistent,found
R2319 T10012 T10010 prep with,Consistent
R2320 T10013 T10014 det a,defect
R2321 T10014 T10012 pobj defect,with
R2322 T10015 T10014 prep in,defect
R2323 T10016 T10017 amod mitochondrial,biogenesis
R2324 T10017 T10015 pobj biogenesis,in
R2325 T10018 T10011 punct ", ",found
R2326 T10019 T10011 nsubj we,found
R2327 T10020 T10021 det a,reduction
R2328 T10021 T10011 dobj reduction,found
R2329 T10022 T10021 prep in,reduction
R2330 T10023 T10024 det the,expression
R2331 T10024 T10022 pobj expression,in
R2332 T10025 T10024 prep of,expression
R2333 T10026 T10027 amod nuclear,genes
R2334 T10027 T10025 pobj genes,of
R2335 T10028 T10027 acl encoding,genes
R2336 T10029 T10028 dobj proteins,encoding
R2337 T10030 T10029 acl involved,proteins
R2338 T10031 T10030 prep in,involved
R2339 T10032 T10033 amod mitochondrial,transport
R2340 T10033 T10031 pobj transport,in
R2341 T10034 T10033 compound electron,transport
R2342 T10035 T10029 punct (,proteins
R2343 T10036 T10037 compound cytochrome,c
R2344 T10037 T10029 appos c,proteins
R2345 T10038 T10037 cc and,c
R2346 T10039 T10040 compound cytochrome,oxidase
R2347 T10040 T10037 conj oxidase,c
R2348 T10041 T10040 nummod IV,oxidase
R2349 T10042 T10029 punct ),proteins
R2350 T10043 T10029 cc and,proteins
R2351 T10044 T10045 amod oxidative,phosphorylation
R2352 T10045 T10029 conj phosphorylation,proteins
R2353 T10046 T10045 punct (,phosphorylation
R2354 T10047 T10048 compound beta,subunit
R2355 T10048 T10045 appos subunit,phosphorylation
R2356 T10049 T10048 prep of,subunit
R2357 T10050 T10051 compound ATP,synthase
R2358 T10051 T10049 pobj synthase,of
R2359 T10052 T10028 punct ),encoding
R2360 T10053 T10028 prep in,encoding
R2361 T10054 T10055 compound soleus,muscle
R2362 T10055 T10053 pobj muscle,in
R2363 T10056 T10055 prep of,muscle
R2364 T10057 T10058 nmod PGC,1α
R2365 T10058 T10060 nmod 1α,mice
R2366 T10059 T10058 punct -,1α
R2367 T10060 T10056 pobj mice,of
R2368 T10061 T10058 punct −,1α
R2369 T10062 T10058 punct /,1α
R2370 T10063 T10058 punct −,1α
R2371 T10064 T10011 prep compared,found
R2372 T10065 T10064 prep with,compared
R2373 T10066 T10067 nmod PGC,1α
R2374 T10067 T10069 nmod 1α,controls
R2375 T10068 T10067 punct -,1α
R2376 T10069 T10065 pobj controls,with
R2377 T10070 T10067 punct +,1α
R2378 T10071 T10067 punct /,1α
R2379 T10072 T10067 punct +,1α
R2380 T10073 T10011 punct .,found
R2381 T10075 T10076 prep In,diminished
R2382 T10077 T10075 pobj addition,In
R2383 T10078 T10076 punct ", ",diminished
R2384 T10079 T10080 det the,expression
R2385 T10080 T10076 nsubjpass expression,diminished
R2386 T10081 T10080 prep of,expression
R2387 T10082 T10081 pobj Tfam,of
R2388 T10083 T10082 punct ", ",Tfam
R2389 T10084 T10085 det a,target
R2390 T10085 T10082 appos target,Tfam
R2391 T10086 T10085 amod known,target
R2392 T10087 T10088 compound PGC,1α
R2393 T10088 T10085 compound 1α,target
R2394 T10089 T10088 punct -,1α
R2395 T10090 T10085 acl involved,target
R2396 T10091 T10090 prep in,involved
R2397 T10092 T10093 amod mitochondrial,transcription
R2398 T10093 T10091 pobj transcription,in
R2399 T10094 T10093 compound DNA,transcription
R2400 T10095 T10093 compound replication,transcription
R2401 T10096 T10093 punct /,transcription
R2402 T10097 T10076 punct ", ",diminished
R2403 T10098 T10076 auxpass was,diminished
R2404 T10099 T10076 prep in,diminished
R2405 T10100 T10101 nmod PGC,1α
R2406 T10101 T10103 nmod 1α,soleus
R2407 T10102 T10101 punct -,1α
R2408 T10103 T10099 pobj soleus,in
R2409 T10104 T10101 punct −,1α
R2410 T10105 T10101 punct /,1α
R2411 T10106 T10101 punct −,1α
R2412 T10107 T10076 punct ", ",diminished
R2413 T10108 T10076 advcl providing,diminished
R2414 T10109 T10110 nummod one,mechanism
R2415 T10110 T10108 dobj mechanism,providing
R2416 T10111 T10110 amod potential,mechanism
R2417 T10112 T10110 prep for,mechanism
R2418 T10113 T10114 amod defective,biogenesis
R2419 T10114 T10112 pobj biogenesis,for
R2420 T10115 T10114 amod mitochondrial,biogenesis
R2421 T10116 T10117 punct (,3C
R2422 T10117 T10076 parataxis 3C,diminished
R2423 T10118 T10117 compound Figure,3C
R2424 T10119 T10117 punct ),3C
R2425 T10120 T10076 punct .,diminished
R2426 T10122 T10123 prep In,noted
R2427 T10124 T10122 pobj contrast,In
R2428 T10125 T10124 prep to,contrast
R2429 T10126 T10127 det the,results
R2430 T10127 T10125 pobj results,to
R2431 T10128 T10127 prep with,results
R2432 T10129 T10128 pobj soleus,with
R2433 T10130 T10123 punct ", ",noted
R2434 T10131 T10132 det no,differences
R2435 T10132 T10123 nsubjpass differences,noted
R2436 T10133 T10132 amod significant,differences
R2437 T10134 T10132 prep in,differences
R2438 T10135 T10136 amod mitochondrial,ultrastructure
R2439 T10136 T10134 pobj ultrastructure,in
R2440 T10137 T10136 cc or,ultrastructure
R2441 T10138 T10139 compound volume,density
R2442 T10139 T10136 conj density,ultrastructure
R2443 T10140 T10123 auxpass were,noted
R2444 T10141 T10123 prep in,noted
R2445 T10142 T10141 pobj heart,in
R2446 T10143 T10142 cc or,heart
R2447 T10144 T10142 conj BAT,heart
R2448 T10145 T10142 prep of,heart
R2449 T10146 T10147 nmod PGC,1α
R2450 T10147 T10149 nmod 1α,mice
R2451 T10148 T10147 punct -,1α
R2452 T10149 T10145 pobj mice,of
R2453 T10150 T10147 punct −,1α
R2454 T10151 T10147 punct /,1α
R2455 T10152 T10147 punct −,1α
R2456 T10153 T10154 punct (,data
R2457 T10154 T10123 meta data,noted
R2458 T10155 T10154 amod unpublished,data
R2459 T10156 T10154 punct ),data
R2460 T10157 T10123 punct .,noted