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PMC:2664230 / 16967-25060 JSONTXT 20 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T10111 184-194 Gene_expression denotes production
T10109 231-236 Protein denotes TNF-α
T10112 240-248 Localization denotes released
T10114 461-470 Positive_regulation denotes increased
T10110 471-476 Protein denotes TNF-α
T10113 477-486 Gene_expression denotes synthesis
T10116 706-716 Negative_regulation denotes decreasing
T10115 717-722 Protein denotes TNF-α
T10118 733-744 Regulation denotes attenuating
T10117 749-759 Gene_expression denotes production
T10119 777-780 Protein denotes PDE
T10121 781-791 Negative_regulation denotes inhibitors
T10123 811-823 Negative_regulation denotes downregulate
T10120 824-829 Protein denotes TNF-α
T10122 830-840 Gene_expression denotes production
T10124 920-925 Protein denotes TNF-α
T10127 926-932 Gene_expression denotes levels
T10128 945-953 Positive_regulation denotes increase
T10125 1057-1062 Protein denotes TNF-α
T10130 1126-1137 Negative_regulation denotes attenuation
T10126 1153-1158 Protein denotes TNF-α
T10129 1159-1169 Gene_expression denotes expression
T10131 1254-1257 Protein denotes PTX
T10134 1334-1343 Negative_regulation denotes decreases
T10132 1344-1349 Protein denotes TNF-α
T10133 1350-1360 Gene_expression denotes production
T10136 1515-1525 Positive_regulation denotes activation
T10135 1529-1532 Protein denotes PKA
T10137 1702-1705 Protein denotes PKA
T10142 1807-1818 Negative_regulation denotes attenuation
T10138 1822-1827 Protein denotes TNF-α
T10140 1828-1838 Gene_expression denotes production
T10139 1926-1929 Protein denotes PKA
T10141 1930-1940 Positive_regulation denotes activation
T10143 1993-1996 Protein denotes PTX
T10144 2221-2224 Protein denotes PTX
T10147 2338-2345 Regulation denotes effects
T10145 2349-2354 Protein denotes TNF-α
T10146 2355-2364 Gene_expression denotes synthesis
T10148 2410-2413 Protein denotes PTX
T10154 2442-2456 Negative_regulation denotes downregulation
T10149 2460-2468 Protein denotes TNF-αbut
T10150 2477-2480 Protein denotes PTX
T10151 2706-2709 Protein denotes PTX
T10152 2782-2787 Protein denotes NF-κB
T10153 2792-2796 Protein denotes CREB
T10155 2868-2873 Protein denotes NF-κB
T10156 2874-2877 Protein denotes Rel
T10157 3058-3063 Protein denotes NF-κB
T10158 3071-3074 Protein denotes p50
T10159 3075-3078 Protein denotes p65
T10160 3115-3120 Protein denotes NF-κB
T10162 3145-3150 Binding denotes bound
T10161 3187-3192 Protein denotes I-κBα
T10163 3259-3264 Protein denotes NF-κB
T10169 3265-3274 Positive_regulation denotes inducible
T10170 3282-3296 Phosphorylation denotes phosphorylates
T10171 3282-3296 Positive_regulation denotes phosphorylates
T10176 3301-3310 Positive_regulation denotes activates
T10177 3301-3310 Positive_regulation denotes activates
T10178 3301-3310 Positive_regulation denotes activates
T10164 3315-3326 Protein denotes I-κB kinase
T10165 3328-3331 Protein denotes IKK
T10172 3333-3340 Entity denotes complex
T10166 3355-3360 Protein denotes IKK-1
T10167 3365-3370 Protein denotes IKK-2
T10173 3386-3400 Phosphorylation denotes phosphorylates
T10174 3386-3400 Phosphorylation denotes phosphorylates
T10175 3386-3400 Phosphorylation denotes phosphorylates
T10168 3405-3418 Protein denotes I-κBα subunit
T10181 3420-3435 Phosphorylation denotes Phosphorylation
T10182 3468-3479 Protein_catabolism denotes degradation
T10179 3483-3488 Protein denotes I-κBα
T10180 3500-3505 Protein denotes NF-κB
T10183 3506-3513 Entity denotes nuclear
T10184 3514-3527 Localization denotes translocation
T10189 3569-3573 Binding denotes bind
T10185 3693-3701 Protein denotes κB sites
T10186 3749-3759 Protein denotes TNF-α gene
T10187 3761-3766 Protein denotes NF-κB
T10191 3821-3829 Regulation denotes involved
T10188 3833-3843 Protein denotes TNF-α gene
T10190 3844-3854 Gene_expression denotes expression
T10202 3936-3949 Negative_regulation denotes downregulates
T10203 3936-3949 Negative_regulation denotes downregulates
T10204 3936-3949 Negative_regulation denotes downregulates
T10192 3964-3967 Protein denotes κBα
T10197 3968-3983 Phosphorylation denotes phosphorylation
T10198 3985-3992 Entity denotes nuclear
T10193 3999-4002 Protein denotes p65
T10199 4003-4032 Phosphorylation denotes phosphorylation/translocation
T10194 4045-4050 Protein denotes NF-κB
T10200 4051-4062 Binding denotes DNA-binding
T10195 4102-4105 Protein denotes PTX
T10205 4148-4153 Positive_regulation denotes level
T10196 4157-4162 Protein denotes I-κBα
T10201 4163-4178 Phosphorylation denotes phosphorylation
T10206 4256-4261 Protein denotes I-κBα
T10207 4266-4271 Protein denotes NF-κB
T10208 4385-4397 Protein denotes PTX on I-κBα
T10209 4402-4407 Protein denotes NF-κB
T10214 4526-4537 Binding denotes interaction
T10210 4546-4551 Protein denotes I-κBα
T10211 4556-4561 Protein denotes NF-κB
T10215 4573-4581 Negative_regulation denotes reducing
T10212 4582-4587 Protein denotes NF-κB
T10217 4642-4652 Regulation denotes difference
T10213 4656-4661 Protein denotes I-κBα
T10216 4662-4673 Protein_catabolism denotes degradation
T10222 4831-4838 Negative_regulation denotes inhibit
T10218 4867-4872 Protein denotes NF-κB
T10219 4882-4886 Protein denotes CREB
T10223 4925-4933 Negative_regulation denotes decrease
T10220 4937-4940 Protein denotes p65
T10221 5167-5170 Protein denotes PKA
T10224 5349-5352 Protein denotes PTX
T10225 5397-5402 Protein denotes NF-κB
T10226 5426-5429 Protein denotes PKA
T10235 5461-5472 Negative_regulation denotes attenuation
T10236 5461-5472 Negative_regulation denotes attenuation
T10233 5476-5487 Positive_regulation denotes LPS-induced
T10234 5476-5487 Positive_regulation denotes LPS-induced
T10227 5488-5493 Protein denotes TNF-α
T10230 5494-5504 Gene_expression denotes production
T10231 5494-5504 Gene_expression denotes production
T10228 5508-5511 Protein denotes PTX
T10229 5542-5545 Protein denotes PKA
T10232 5546-5556 Negative_regulation denotes inhibition
T10237 5682-5685 Protein denotes PKA
T10239 5686-5695 Negative_regulation denotes inhibitor
T10238 5795-5798 Protein denotes PKA
T10240 5877-5880 Protein denotes PTX
T10241 5917-5920 Protein denotes PDE
T10245 5921-5931 Negative_regulation denotes inhibitors
T10242 5954-5959 Protein denotes NF-κB
T10248 5988-5996 Positive_regulation denotes altering
T10249 5988-5996 Positive_regulation denotes altering
T10246 6013-6020 Binding denotes binding
T10247 6013-6020 Binding denotes binding
T10243 6024-6028 Protein denotes CREB
T10244 6033-6038 Protein denotes NF-κB
T10251 6117-6127 Positive_regulation denotes activation
T10254 6117-6127 Positive_regulation denotes activation
T10252 6136-6143 Binding denotes binding
T10250 6156-6160 Protein denotes CREB
T10253 6164-6175 Positive_regulation denotes upregulated
T10259 6224-6232 Positive_regulation denotes increase
T10255 6236-6240 Protein denotes CREB
T10256 6329-6332 Protein denotes PTX
T10257 6341-6345 Protein denotes CREB
T10258 6403-6408 Protein denotes NF-κB
T10260 6423-6434 Positive_regulation denotes upregulated
T10264 6504-6515 Binding denotes recruitment
T10261 6536-6539 Protein denotes CBP
T10262 6558-6564 Protein denotes p30034
T10263 6659-6662 Protein denotes PTX
T10267 6750-6757 Regulation denotes effects
T10268 6750-6757 Regulation denotes effects
T10265 6805-6809 Protein denotes AP-1
T10266 6811-6816 Protein denotes c-fos
T10273 6869-6879 Positive_regulation denotes Activation
T10274 6869-6879 Positive_regulation denotes Activation
T10275 6869-6879 Positive_regulation denotes Activation
T10269 6883-6887 Protein denotes AP-1
T10270 6910-6913 Protein denotes fos
T10271 6918-6923 Protein denotes c-jun
T10272 6997-7002 Protein denotes TNF-α
T10276 7003-7013 Gene_expression denotes expression
T10277 7025-7029 Protein denotes AP-1
T10278 7034-7038 Protein denotes CREB
T10280 7039-7048 Binding denotes recognize
T10279 7110-7122 Protein denotes TNF-α gene35
T10281 7174-7177 Protein denotes PTX
T10288 7229-7238 Regulation denotes affecting
T10282 7239-7243 Protein denotes AP-1
T10285 7244-7254 Positive_regulation denotes activation
T10289 7259-7267 Positive_regulation denotes favoring
T10283 7268-7272 Protein denotes CREB
T10286 7273-7280 Binding denotes binding
T10290 7287-7297 Negative_regulation denotes inhibiting
T10284 7298-7308 Protein denotes TNF-α gene
T10287 7309-7322 Transcription denotes transcription
T10291 7403-7407 Protein denotes CREB
T10292 7409-7414 Protein denotes NF-κB
T10293 7420-7424 Protein denotes AP-1
T10294 7495-7498 Protein denotes PTX
T10295 7643-7646 Protein denotes PDE
T10298 7647-7657 Negative_regulation denotes inhibition
T10300 7685-7698 Negative_regulation denotes downregulates
T10296 7699-7704 Protein denotes TNF-α
T10299 7705-7715 Gene_expression denotes production
T10297 7745-7748 Protein denotes PKA
T10301 7785-7788 Protein denotes PTX
T10302 7816-7820 Protein denotes NF-B
T10305 7827-7839 Positive_regulation denotes upregulating
T10303 7840-7844 Protein denotes CREB
T10304 7845-7855 Positive_regulation denotes activation
T10306 7961-7964 Protein denotes PTX
T10307 8051-8056 Protein denotes TNF-α
T10308 8057-8067 Gene_expression denotes production
R8201 T10109 T10111 themeOf TNF-α,production
R8202 T10109 T10112 themeOf TNF-α,released
R8203 T10110 T10113 themeOf TNF-α,synthesis
R8204 T10113 T10114 themeOf synthesis,increased
R8205 T10115 T10116 themeOf TNF-α,decreasing
R8206 T10115 T10117 themeOf TNF-α,production
R8207 T10117 T10118 themeOf production,attenuating
R8208 T10119 T10121 themeOf PDE,inhibitors
R8209 T10120 T10122 themeOf TNF-α,production
R8210 T10121 T10123 causeOf inhibitors,downregulate
R8211 T10122 T10123 themeOf production,downregulate
R8212 T10124 T10127 themeOf TNF-α,levels
R8213 T10126 T10129 themeOf TNF-α,expression
R8214 T10127 T10128 themeOf levels,increase
R8215 T10129 T10130 themeOf expression,attenuation
R8216 T10131 T10134 causeOf PTX,decreases
R8217 T10132 T10133 themeOf TNF-α,production
R8218 T10133 T10134 themeOf production,decreases
R8219 T10135 T10136 themeOf PKA,activation
R8220 T10138 T10140 themeOf TNF-α,production
R8221 T10139 T10141 themeOf PKA,activation
R8222 T10140 T10142 themeOf production,attenuation
R8223 T10227 T10230 themeOf TNF-α,production
R8224 T10145 T10146 themeOf TNF-α,synthesis
R8225 T10146 T10147 themeOf synthesis,effects
R8226 T10228 T10231 themeOf PTX,production
R8227 T10149 T10154 themeOf TNF-αbut,downregulation
R8228 T10229 T10232 themeOf PKA,inhibition
R8229 T10230 T10233 themeOf production,LPS-induced
R8230 T10161 T10162 themeOf I-κBα,bound
R8231 T10231 T10234 themeOf production,LPS-induced
R8232 T10163 T10169 themeOf NF-κB,inducible
R8233 T10163 T10170 themeOf NF-κB,phosphorylates
R8234 T10233 T10235 themeOf LPS-induced,attenuation
R8235 T10164 T10173 themeOf I-κB kinase,phosphorylates
R8236 T10164 T10172 partOf I-κB kinase,complex
R8237 T10165 T10174 themeOf IKK,phosphorylates
R8238 T10165 T10172 partOf IKK,complex
R8239 T10167 T10172 partOf IKK-2,complex
R8240 T10168 T10175 themeOf I-κBα subunit,phosphorylates
R8241 T10234 T10236 themeOf LPS-induced,attenuation
R8242 T10170 T10171 themeOf phosphorylates,phosphorylates
R8243 T10237 T10239 themeOf PKA,inhibitor
R8244 T10172 T10173 Site complex,phosphorylates
R8245 T10172 T10174 Site complex,phosphorylates
R8246 T10172 T10175 Site complex,phosphorylates
R8247 T10172 T10176 Site complex,activates
R8248 T10172 T10177 Site complex,activates
R8249 T10172 T10178 Site complex,activates
R8250 T10173 T10176 themeOf phosphorylates,activates
R8251 T10174 T10177 themeOf phosphorylates,activates
R8252 T10175 T10178 themeOf phosphorylates,activates
R8253 T10241 T10245 themeOf PDE,inhibitors
R8254 T10179 T10181 themeOf I-κBα,Phosphorylation
R8255 T10179 T10182 themeOf I-κBα,degradation
R8256 T10180 T10184 themeOf NF-κB,translocation
R8257 T10183 T10184 locationOf nuclear,translocation
R8258 T10243 T10246 themeOf CREB,binding
R8259 T10187 T10189 themeOf NF-κB,bind
R8260 T10188 T10190 themeOf TNF-α gene,expression
R8261 T10244 T10247 themeOf NF-κB,binding
R8262 T10190 T10191 themeOf expression,involved
R8263 T10192 T10197 themeOf κBα,phosphorylation
R8264 T10193 T10199 themeOf p65,phosphorylation/translocation
R8265 T10194 T10200 themeOf NF-κB,DNA-binding
R8266 T10246 T10248 themeOf binding,altering
R8267 T10196 T10201 themeOf I-κBα,phosphorylation
R8268 T10197 T10202 themeOf phosphorylation,downregulates
R8269 T10198 T10199 Site nuclear,phosphorylation/translocation
R8270 T10199 T10203 themeOf phosphorylation/translocation,downregulates
R8271 T10200 T10204 themeOf DNA-binding,downregulates
R8272 T10247 T10249 themeOf binding,altering
R8273 T10201 T10205 themeOf phosphorylation,level
R8274 T10250 T10251 themeOf CREB,activation
R8275 T10250 T10252 themeOf CREB,binding
R8276 T10210 T10214 themeOf I-κBα,interaction
R8277 T10211 T10214 themeOf NF-κB,interaction
R8278 T10213 T10216 themeOf I-κBα,degradation
R8279 T10214 T10215 themeOf interaction,reducing
R8280 T10251 T10253 themeOf activation,upregulated
R8281 T10216 T10217 themeOf degradation,difference
R8282 T10252 T10254 themeOf binding,activation
R8283 T10218 T10222 themeOf NF-κB,inhibit
R8284 T10220 T10223 themeOf p65,decrease
R8285 T10255 T10259 themeOf CREB,increase
R8286 T10258 T10260 themeOf NF-κB,upregulated
R8287 T10261 T10264 themeOf CBP,recruitment
R8288 T10262 T10264 themeOf p30034,recruitment
R8289 T10265 T10267 themeOf AP-1,effects
R8290 T10266 T10268 themeOf c-fos,effects
R8291 T10269 T10273 themeOf AP-1,Activation
R8292 T10270 T10274 themeOf fos,Activation
R8293 T10271 T10275 themeOf c-jun,Activation
R8295 T10272 T10276 themeOf TNF-α,expression
R8296 T10277 T10280 themeOf AP-1,recognize
R8299 T10281 T10288 causeOf PTX,affecting
R8301 T10281 T10290 causeOf PTX,inhibiting
R8302 T10282 T10285 themeOf AP-1,activation
R8304 T10283 T10286 themeOf CREB,binding
R8306 T10284 T10287 themeOf TNF-α gene,transcription
R8307 T10285 T10288 themeOf activation,affecting
R8309 T10286 T10289 themeOf binding,favoring
R8310 T10287 T10290 themeOf transcription,inhibiting
R8312 T10295 T10298 themeOf PDE,inhibition
R8315 T10296 T10299 themeOf TNF-α,production
R8316 T10298 T10300 causeOf inhibition,downregulates
R8318 T10299 T10300 themeOf production,downregulates
R8320 T10303 T10304 themeOf CREB,activation
R8323 T10304 T10305 themeOf activation,upregulating
R8324 T10307 T10308 themeOf TNF-α,production