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PubMed:22834551 JSONTXT 7 Projects

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Id Subject Object Predicate Lexical cue
T1 0-180 Title denotes The effect of Artemisia annua on broiler performance, on intestinal microbiota and on the course of a Clostridium perfringens infection applying a necrotic enteritis disease model.
T3 14-29 Habitat denotes Artemisia annua
T4 33-40 Habitat denotes broiler
T5 57-67 Habitat denotes intestinal
T6 57-78 Habitat denotes intestinal microbiota
T7 102-125 Bacteria denotes Clostridium perfringens
T2 181-1772 Paragraph denotes The aerial parts of the plant Artemisia annua contain essential oils having antimicrobial properties against Clostridium perfringens Type A, the causal agent for necrotic enteritis in broilers. In two experiments, the influence of increasing dietary concentrations of dried A. annua leaves (0, 5, 10 and 20 g/kg) and n-hexane extract from fresh A. annua leaves (0, 125, 250 and 500 mg/kg) on broiler performance was investigated. Dried plant material decreased feed intake and body weight in a dose-dependent manner, and 10 and 20 g/kg diet tended to improve the feed conversion ratio. The n-hexane extract also reduced feed intake, but broiler weight tended to decrease only at the highest dietary concentration. The feed conversion ratio tended to improve when birds received 250 and 500 mg/kg n-hexane extract. In a third experiment, a necrotic enteritis disease model was applied to investigate the effect of the dietary addition of dried A. annua leaves (10 g/kg on top) or n-hexane extract of A. annua (250 mg/kg) on the severity of the disease in broilers. The addition of n-hexane extract reduced the intestinal C. perfringens numbers and the severity of the disease-related small intestinal lesions. Over the infection period from day 17 to day 27, birds supplemented with the n-hexane extract gained more weight than both the challenged control birds and birds receiving dried plant material. The results indicate that n-hexane extracts derived from A. annua can modulate the course of necrotic enteritis and compensate to a certain extent for the disease-associated weight losses.
T8 185-226 Habitat denotes aerial parts of the plant Artemisia annua
T9 205-226 Habitat denotes plant Artemisia annua
T10 235-249 Habitat denotes essential oils
T11 290-320 Bacteria denotes Clostridium perfringens Type A
T12 365-373 Habitat denotes broilers
T13 449-470 Habitat denotes dried A. annua leaves
T14 455-463 Habitat denotes A. annua
T15 498-541 Habitat denotes n-hexane extract from fresh A. annua leaves
T16 520-541 Habitat denotes fresh A. annua leaves
T17 526-534 Habitat denotes A. annua
T18 573-580 Habitat denotes broiler
T19 611-631 Habitat denotes Dried plant material
T20 617-622 Habitat denotes plant
T21 642-646 Habitat denotes feed
T22 658-662 Habitat denotes body
T23 744-748 Habitat denotes feed
T24 801-805 Habitat denotes feed
T25 818-825 Habitat denotes broiler
T26 899-903 Habitat denotes feed
T27 944-949 Habitat denotes birds
T28 977-993 Habitat denotes n-hexane extract
T29 1118-1139 Habitat denotes dried A. annua leaves
T30 1124-1132 Habitat denotes A. annua
T31 1160-1188 Habitat denotes n-hexane extract of A. annua
T32 1180-1188 Habitat denotes A. annua
T33 1235-1243 Habitat denotes broilers
T34 1261-1277 Habitat denotes n-hexane extract
T35 1290-1300 Habitat denotes intestinal
T36 1301-1315 Bacteria denotes C. perfringens
T38 1364-1380 Habitat denotes small intestinal
T37 1364-1388 Habitat denotes small intestinal lesions
T39 1439-1483 Habitat denotes birds supplemented with the n-hexane extract
T40 1467-1483 Habitat denotes n-hexane extract
T41 1517-1541 Habitat denotes challenged control birds
T42 1546-1582 Habitat denotes birds receiving dried plant material
T43 1562-1582 Habitat denotes dried plant material
T44 1568-1573 Habitat denotes plant
T45 1610-1649 Habitat denotes n-hexane extracts derived from A. annua
T46 1641-1649 Habitat denotes A. annua