bionlp-ost-19-BB-norm-test  

BB-norm@ldeleger:BB-norm-12563490 JSONTXT

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Id Subject Object Predicate Lexical cue
T1 0-104 Title denotes Acute inflammatory response in the stomach of BALB/c mice challenged with coccoidal Helicobacter pylori.
T3 35-57 Habitat denotes stomach of BALB/c mice
T4 46-57 Habitat denotes BALB/c mice
T5 74-83 Phenotype denotes coccoidal
T6 84-103 Microorganism denotes Helicobacter pylori
T2 105-1428 Paragraph denotes An experimental murine model was used to verify the viability and pathogenicity of coccoid Helicobacter pylori. For this purpose, 27 BALB/c mice were inoculated intragastrically with 1 ml broth culture (10(8)organisms/ml) of a coccoid H. pylori clinical isolate. The animals were divided into two groups. Nine were infected on a one-time basis (GA1) and 18 were infected on two consecutive days (GA2). Other 27 mice were inoculated with Brucella broth and divided in the same way; they composed the control group. Mice were killed at 2, 3, 7, 14 and 21 days post inoculation (pi). Fragments of stomach and duodenum were collected, fixed with 12% formalin and stained by hematoxilin-eosin and Giemsa for histopathological examination. Until the 14th()day, only reinfected mice had mild-to-moderate inflammatory infiltrate in the stomach. The infiltration was predominantly lymphomonocytic, although plasma cells and eosinophils could be seen. However, at 21st day, severe eosinophilic infiltration was present in the lamina propria and submucosa of gastric corpus. In subgroup GA1, animals presented lymphomonocytic infiltration in the stomach from 14th()day pi. Our results showed that coccoid H. pylori was able to induce an acute inflammatory response in stomach of reinfected mice since the initial periods of infection.
T7 108-133 Habitat denotes experimental murine model
T8 171-184 Phenotype denotes pathogenicity
T9 188-195 Phenotype denotes coccoid
T10 196-215 Microorganism denotes Helicobacter pylori
T11 238-249 Habitat denotes BALB/c mice
T12 266-282 Habitat denotes intragastrically
T13 293-366 Habitat denotes broth culture (10(8)organisms/ml) of a coccoid H. pylori clinical isolate
T14 332-339 Phenotype denotes coccoid
T15 340-349 Microorganism denotes H. pylori
T16 350-358 Habitat denotes clinical
T17 372-379 Habitat denotes animals
T18 516-520 Habitat denotes mice
T19 542-550 Microorganism denotes Brucella
T20 542-556 Habitat denotes Brucella broth
T21 604-617 Habitat denotes control group
T22 619-623 Habitat denotes Mice
T23 699-706 Habitat denotes stomach
T24 711-719 Habitat denotes duodenum
T25 865-880 Habitat denotes reinfected mice
T26 902-925 Habitat denotes inflammatory infiltrate
T27 933-940 Habitat denotes stomach
T28 977-992 Habitat denotes lymphomonocytic
T29 1003-1015 Habitat denotes plasma cells
T30 1020-1031 Habitat denotes eosinophils
T31 1076-1088 Habitat denotes eosinophilic
T32-0 1121-1135 _FRAGMENT denotes lamina propria
T33 1140-1167 Habitat denotes submucosa of gastric corpus
T32-1 1150-1167 Habitat denotes of gastric corpus
T34 1153-1167 Habitat denotes gastric corpus
T35 1186-1193 Habitat denotes animals
T36 1204-1219 Habitat denotes lymphomonocytic
T37 1240-1247 Habitat denotes stomach
T38 1291-1298 Phenotype denotes coccoid
T39 1299-1308 Microorganism denotes H. pylori
T40 1362-1388 Habitat denotes stomach of reinfected mice
T41 1373-1388 Habitat denotes reinfected mice
C-T32-0 T32-1 T32-0 _lexicallyChainedTo of gastric corpus,lamina propria