PubMed:11455775 JSONTXT 4 Projects

[Unusual localization of granulosa cell tumor]. Localización poco habitual de un tumor de células granulosas. OBJECTIVE: To present a case of granular cell tumor with an uncommon localization. METHODS: A 38-year-old patient presented with a painless nodule 10 mm in diameter on the scrotum that he had noted two years earlier. RESULTS: The tumor was surgically excised. Pathological analysis demonstrated a granular cell tumor that was strongly positive for protein S-100 and negative for cytokeratin AE1-AE3 and CEA. CONCLUSIONS: Granular cell tumors are very frequent in the head and neck, but rare in the genitourinary region and are asymptomatic. Histological diagnosis is simple but should be confirmed by protein S-100 staining, which is positive in all cases. Treatment is by simple excision of the lesion. Tumor recurrence and metastasis have been reported, therefore follow-up is necessary.