SMAFIRA-Case-Studies-21494637  

Documents (103) JSON TSV

source DB source ID text size updated at # proj. # Ann. updated_at
PubMed 29054882 Parkinson's Disease-Associated LRRK2 Hyperactive Kinase Mutant Disrupts Synaptic Vesicle Trafficking 2.33 KB 2020-01-29 33 0
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PubMed 21454543 Rac1 protein rescues neurite retraction caused by G2019S leucine-rich repeat kinase 2 (LRRK2). Mutat 1.88 KB 2020-01-21 30 0
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PubMed 24725412 Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease. Mutat 1.12 KB 2020-01-29 23 0
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PubMed 24874075 Mutant LRRK2 enhances glutamatergic synapse activity and evokes excitotoxic dendrite degeneration. M 1.44 KB 2020-01-28 21 0
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PubMed 25446991 Threonine 56 phosphorylation of Bcl-2 is required for LRRK2 G2019S-induced mitochondrial depolarizat 864 Bytes 2020-01-22 20 0
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PubMed 25174649 Behavioral, neurochemical, and pathologic alterations in bacterial artificial chromosome transgenic 1.4 KB 2020-01-21 15 0
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PubMed 25731749 Adenoviral-mediated expression of G2019S LRRK2 induces striatal pathology in a kinase-dependent mann 2 KB 2020-01-29 15 0
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PubMed 21972245 Transcriptional responses to loss or gain of function of the leucine-rich repeat kinase 2 (LRRK2) ge 1.86 KB 2020-01-21 15 0
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PubMed 23065705 Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity. Mutation 1.94 KB 2020-01-22 14 0
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PubMed 24459295 Thiol peroxidases ameliorate LRRK2 mutant-induced mitochondrial and dopaminergic neuronal degenerati 1.48 KB 2020-01-21 14 0
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