| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-53 |
Sentence |
denotes |
Hydroxychloroquine in hospitalized COVID-19 patients: |
| T2 |
54-96 |
Sentence |
denotes |
Real world experience assessing mortality. |
| T3 |
97-110 |
Sentence |
denotes |
INTRODUCTION: |
| T4 |
111-210 |
Sentence |
denotes |
Hydroxychloroquine (HCQ) for COVID-19 is presently being used off-label or within a clinical trial. |
| T5 |
211-222 |
Sentence |
denotes |
OBJECTIVES: |
| T6 |
223-354 |
Sentence |
denotes |
We investigated a multinational COVID-19 patient database of real world data containing outcomes and their relationship to HCQ use. |
| T7 |
355-424 |
Sentence |
denotes |
The primary outcome was all-cause mortality within 30 days follow-up. |
| T8 |
425-433 |
Sentence |
denotes |
METHODS: |
| T9 |
434-525 |
Sentence |
denotes |
Retrospective cohort study of patients receiving HCQ within 48 hours of hospital admission. |
| T10 |
526-622 |
Sentence |
denotes |
Medications, preexisting conditions, clinical measures on admission, and outcomes were recorded. |
| T11 |
623-631 |
Sentence |
denotes |
RESULTS: |
| T12 |
632-837 |
Sentence |
denotes |
Among patients with a diagnosis of COVID-19 in our propensity matched cohort, the mean ages±SD were 62.3±15.9 years (53.7% male) and 61.9±16.0 years (53.0% male) in the HCQ and no-HCQ groups, respectively. |
| T13 |
838-1017 |
Sentence |
denotes |
There was no difference in overall 30-day mortality between the HCQ and no-HCQ groups (HCQ 13.1%, n=367; No-HCQ 13.6%, n=367; OR 0.95; 95% CI 0.62-1.46) after propensity-matching. |
| T14 |
1018-1238 |
Sentence |
denotes |
Although statistically insignificant, the HCQ/azithromycin (AZ) group had an overall mortality rate of 14.6% (n=199) compared with propensity matched no HCQ/+AZ cohort's rate of 12.1% (n=199) (OR 1.24; 95% CI 0.70-2.22). |
| T15 |
1239-1399 |
Sentence |
denotes |
Importantly, however, there was no trend in this cohort's overall mortality/arrhythmogenesis outcome (HCQ/AZ 17.1%, No-HCQ/No AZ 17.1%; OR 1.0; 95% CI 0.6-1.7). |
| T16 |
1400-1412 |
Sentence |
denotes |
CONCLUSIONS: |
| T17 |
1413-1559 |
Sentence |
denotes |
We report from a large retrospective multinational database analysis of COVID-19 outcomes with HCQ and overall mortality in hospitalized patients. |
| T18 |
1560-1665 |
Sentence |
denotes |
There was no statistically significant increase in mortality and mortality/arrhythmia with HCQ or HCQ/AZ. |
