PubMed:32881209 JSONTXT 19 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 0-60 Sentence denotes Approach to the Patient with COVID-19-Associated Thrombosis:
T2 61-81 Sentence denotes A Case-Based Review.
T3 82-190 Sentence denotes Coronavirus disease 2019 (COVID-19) is a current global pandemic caused by the novel coronavirus SARS-CoV-2.
T4 191-460 Sentence denotes Alongside its potential to cause severe respiratory illness, studies have reported a distinct COVID-19-associated coagulopathy that is characterized by elevated D-dimer levels, hyperfibrinogenemia, mild thrombocytopenia, and slight prolongation of the prothrombin time.
T5 461-707 Sentence denotes Studies have also reported increased rates of thromboembolism in patients with COVID-19, but variations in study methodologies, patient populations, and anticoagulation strategies make it challenging to distill implications for clinical practice.
T6 708-881 Sentence denotes Here, we present a practical review of current literature and uses a case-based format to discuss the diagnostic approach and management of COVID-19-associated coagulopathy.
T7 882-908 Sentence denotes IMPLICATIONS FOR PRACTICE:
T8 909-1074 Sentence denotes Coronavirus disease 2019 (COVID-19)-associated coagulopathy is characterized by elevated D-dimer levels, hyperfibrinogenemia, and increased rates of thromboembolism.
T9 1075-1199 Sentence denotes Current management guidelines are based on limited evidence from retrospective studies that should be interpreted carefully.
T10 1200-1489 Sentence denotes At this time, all hospitalized patients with suspected or confirmed COVID-19 should receive coagulation test surveillance and standard doses of prophylactic anticoagulation until prospective randomized controlled trials yield definitive information in support of higher prophylactic doses.