LitCovid-sentences  

PubMed:32734353 JSONTXT 20 Projects

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Id Subject Object Predicate Lexical cue
T1 0-71 Sentence denotes Immune-mediated neurological syndromes in SARS-CoV-2-infected patients.
T2 72-83 Sentence denotes BACKGROUND:
T3 84-235 Sentence denotes Evidence of immune-mediated neurological syndromes associated with the severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection is limited.
T4 236-382 Sentence denotes We therefore investigated clinical, serological and CSF features of coronavirus disease 2019 (COVID-19) patients with neurological manifestations.
T5 383-391 Sentence denotes METHODS:
T6 392-598 Sentence denotes Consecutive COVID-19 patients with neurological manifestations other than isolated anosmia and/or non-severe headache, and with no previous neurological or psychiatric disorders were prospectively included.
T7 599-734 Sentence denotes Neurological examination was performed in all patients and lumbar puncture with CSF examination was performed when not contraindicated.
T8 735-808 Sentence denotes Serum anti-gangliosides antibodies were tested when clinically indicated.
T9 809-817 Sentence denotes RESULTS:
T10 818-1005 Sentence denotes Of the 349 COVID-19 admitted to our center between March 23rd and April 24th 2020, 15 patients (4.3%) had neurological manifestations and fulfilled the study inclusion/exclusion criteria.
T11 1006-1100 Sentence denotes CSF examination was available in 13 patients and showed lymphocytic pleocytosis in 2 patients:
T12 1101-1215 Sentence denotes 1 with anti-contactin-associated protein 2 (anti-Caspr2) antibody encephalitis and 1 with meningo-polyradiculitis.
T13 1216-1442 Sentence denotes Increased serum titer of anti-GD1b antibodies was found in three patients and was associated with variable clinical presentations, including cranial neuropathy with meningo-polyradiculitis, brainstem encephalitis and delirium.
T14 1443-1495 Sentence denotes CSF PCR for SARS-CoV-2 was negative in all patients.
T15 1496-1508 Sentence denotes CONCLUSIONS:
T16 1509-1668 Sentence denotes In SARS-Cov-2 infected patients with neurological manifestations, CSF pleocytosis is associated with para- or post-infectious encephalitis and polyradiculitis.
T17 1669-1812 Sentence denotes Anti-GD1b and anti-Caspr2 autoantibodies can be identified in certain cases, raising the question of SARS-CoV-2-induced secondary autoimmunity.