302 Found
LitCovid-sentences  

PubMed:32172226 JSONTXT 37 Projects

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Id Subject Object Predicate Lexical cue
T1 0-77 Sentence denotes Prominent changes in blood coagulation of patients with SARS-CoV-2 infection.
T2 78-276 Sentence denotes Background As the number of patients increases, there is a growing understanding of the form of pneumonia sustained by the 2019 novel coronavirus (SARS-CoV-2), which has caused an outbreak in China.
T3 277-386 Sentence denotes Up to now, clinical features and treatment of patients infected with SARS-CoV-2 have been reported in detail.
T4 387-476 Sentence denotes However, the relationship between SARS-CoV-2 and coagulation has been scarcely addressed.
T5 477-572 Sentence denotes Our aim is to investigate the blood coagulation function of patients with SARS-CoV-2 infection.
T6 573-696 Sentence denotes Methods In our study, 94 patients with confirmed SARS-CoV-2 infection were admitted in Renmin Hospital of Wuhan University.
T7 697-813 Sentence denotes We prospectively collect blood coagulation data in these patients and in 40 healthy controls during the same period.
T8 814-908 Sentence denotes Results Antithrombin values in patients were lower than that in the control group (p < 0.001).
T9 909-1080 Sentence denotes The values of D-dimer, fibrin/fibrinogen degradation products (FDP), and fibrinogen (FIB) in all SARS-CoV-2 cases were substantially higher than those in healthy controls.
T10 1081-1212 Sentence denotes Moreover, D-dimer and FDP values in patients with severe SARS-CoV-2 infection were higher than those in patients with milder forms.
T11 1213-1313 Sentence denotes Compared with healthy controls, prothrombin time activity (PT-act) was lower in SARS-CoV-2 patients.
T12 1314-1399 Sentence denotes Thrombin time in critical SARS-CoV-2 patients was also shorter than that in controls.
T13 1400-1619 Sentence denotes Conclusions The coagulation function in patients with SARS-CoV-2 is significantly deranged compared with healthy people, but monitoring D-dimer and FDP values may be helpful for the early identification of severe cases.