LitCovid-sentences  

PMC:7799377 / 37394-41565 JSONTXT 3 Projects

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Id Subject Object Predicate Lexical cue
T251 0-65 Sentence denotes Clinical management of neurological symptoms in COVID-19 patients
T252 66-324 Sentence denotes Symptoms frequently reported by COVID-19 patients, such as headache, dizziness, nausea, vomiting, confusion, and fatigue may be neurological, or they may actually be manifestations of hypoxia, respiratory distress, metabolic acidosis, or drug reactions [84].
T253 325-505 Sentence denotes Such generalized symptoms occur with many types of infections, can be vague and diffuse, and may be difficult for the patient to associate specifically with the COVID-19 infection.
T254 506-652 Sentence denotes Thus, many neurological manifestations of COVID-19 are overlooked, particularly in a pandemic situation when healthcare resources are overwhelmed.
T255 653-757 Sentence denotes For that reason, it is important to consider neurological assessments of hospitalized COVID-19 patients.
T256 758-870 Sentence denotes Serum urea, creatinine, electrolyte, and blood gas tests may be helpful to indicate if there is CNS involvement.
T257 871-1004 Sentence denotes The loss of smell and/or taste early in the course of the disease may be significant and point toward neurological involvement [117].
T258 1005-1265 Sentence denotes Alterations to the senses of taste and smell have been reported in early-stage COVID-19 cases without complications and suggest that the virus is moving toward the olfactory bulb of the brain, which would permit it to enter and possibly affect the brain [118].
T259 1266-1404 Sentence denotes However, it must be noted that anosmia and ageusia can also be reported in the setting of non-COVID-19 upper respiratory tract infections.
T260 1405-1541 Sentence denotes Treating neurological symptoms can be challenging as drugs that suppress the immune system may be contraindicated for COVID-19 patients.
T261 1542-1629 Sentence denotes There is evidence that the use of corticosteroids may prolong viral shedding [119,120].
T262 1630-1952 Sentence denotes Symptoms for neurological problems may be addressed, with first-line strategies such as controlling body temperature, offering anticonvulsants, and treating hypoxia.21 Second-line treatments for neuroinflammation involve IV immunoglobulin or plasma exchange, but IV immunoglobulin may increase the risk of thromboembolism.
T263 1953-2057 Sentence denotes Furthermore, there is emerging concern of the possibility of microthrombosis in COVID-19 patients [121].
T264 2058-2224 Sentence denotes Third-line strategies for neuroinflammation in COVID patients may carry higher risks, and include such pharmacological agents as cyclophosphamide and rituximab [121].
T265 2225-2376 Sentence denotes Typically, COVID-19 patients present with respiratory symptoms before neurological ones, but atypical presentations, although rare, have been reported.
T266 2377-2583 Sentence denotes When neurological symptoms are present in suspected COVID-19 patients, it may be important to test and, if necessary, treat them for COVID-19 first and then address the neurological disorder afterward [49].
T267 2584-2738 Sentence denotes Although not yet fully characterized, neurological symptoms related to COVID-19 are thought to be possible following resolution of the COVID-19 infection.
T268 2739-3007 Sentence denotes In the hospital, distinct and separate areas for neurological emergencies versus COVID-related emergencies may be helpful in order to preclude that a patient with a neurological emergency but not COVID-19 does not come inadvertently in contact with a COVID-19 patient.
T269 3008-3220 Sentence denotes When treating patients with neurological symptoms but no confirmed COVID-19 diagnosis, physicians, and other clinicians should ask about fever, sore throat, exposure history in the past two weeks, and so on [49].
T270 3221-3318 Sentence denotes Testing is important, particularly if there is any reason to suspect possible COVID-19 infection.
T271 3319-3496 Sentence denotes COVID-19 patients who have suffered neurological complications, including stroke, may require acute rehabilitation or, in some cases, long-term residential-skilled nursing care.
T272 3497-3801 Sentence denotes Some patients who undergo prolonged hospitalization with extended periods prone in bed during mechanical ventilation may present following hospitalization with myopathy or neuropathy following acute respiratory distress syndrome, possibly necessitating extracorporeal membrane oxygenation (ECMO) therapy.
T273 3802-3926 Sentence denotes Other presentations may include reversible posterior encephalopathy or the sequela of severe stroke of a large blood vessel.
T274 3927-4171 Sentence denotes Weakness acquired through prolonged stays in intensive care, critical-illness polymyopathy, or polyneuropathy can occur with acute respiratory distress syndrome and may require a multidisciplinary approach for rehabilitation and recovery [122].