| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T24 |
0-2 |
Sentence |
denotes |
1. |
| T25 |
3-15 |
Sentence |
denotes |
Introduction |
| T26 |
16-153 |
Sentence |
denotes |
The global pandemic caused by coronavirus disease 2019 (COVID-19) continues to evolve and exerts tremendous strain on healthcare systems. |
| T27 |
154-325 |
Sentence |
denotes |
Pathomechanisms differentiating patients at high risk for adverse outcomes from those displaying minor symptoms and a mild course of disease are insufficiently understood. |
| T28 |
326-483 |
Sentence |
denotes |
Cardiovascular involvement and myocardial injury are commonly observed and associated prognostic implications have been suggested by early reports [1,2,3,4]. |
| T29 |
484-603 |
Sentence |
denotes |
Impairment of ventricular function and inflammatory myocardial processes have been detected in COVID-19 patients [5,6]. |
| T30 |
604-760 |
Sentence |
denotes |
However, evidence regarding prevalence and prognostic effects of cardiac arrhythmias in COVID-19 is sparse and mainly limited to single center observations. |
| T31 |
761-933 |
Sentence |
denotes |
Early studies among the first patient cohorts analyzed in China reported an incidence of cardiac arrhythmia of 17%, with rates of up to 44% in patients admitted to ICU [7]. |
| T32 |
934-1016 |
Sentence |
denotes |
However, there was no information on the respective types of arrhythmia diagnosed. |
| T33 |
1017-1205 |
Sentence |
denotes |
Another monocentric study from Pennsylvania reported similar rates of arrhythmia events during hospitalization for COVID-19, in particular in patients treated in an intensive care setting. |
| T34 |
1206-1264 |
Sentence |
denotes |
AF was identified as the most common arrhythmic event [8]. |
| T35 |
1265-1513 |
Sentence |
denotes |
In a cohort of 30 patients from Italy, a possible association of cardiac arrhythmias and increased inflammatory markers as well as mortality in COVID-19 was pointed out, however, with limited reliability of results due to the small sample size [9]. |
| T36 |
1514-1727 |
Sentence |
denotes |
Insight into the role of arrhythmias in COVID-19 is of particular importance as widely used pharmacological therapies attempting to mitigate the course of disease may be associated with proarrhythmic effects [10]. |
| T37 |
1728-2012 |
Sentence |
denotes |
This study aims to systematically investigate the prevalence of cardiac arrhythmias in patients hospitalized for COVID-19 at multiple centers, to identify risk factors for the occurrence of cardiac arrhythmias, and to assess their role regarding clinical course and patient prognosis. |
