Id |
Subject |
Object |
Predicate |
Lexical cue |
T33 |
0-72 |
Sentence |
denotes |
While the research is going on to identify an active agent for COVID-19. |
T34 |
73-179 |
Sentence |
denotes |
Identifying the mode of delivering the active moieties to patients and healthy subjects cannot be ignored. |
T35 |
180-335 |
Sentence |
denotes |
At present, there are several drug delivery systems, whereas the most novel and transformative drug delivery/carrier system is orodispersible films (ODFs). |
T36 |
336-363 |
Sentence |
denotes |
European Pharmacopoeia (Ph. |
T37 |
364-500 |
Sentence |
denotes |
Eur.) defines ODFs as ‘single or multilayered sheets of suitable materials, to be placed in the mouth where they disperse rapidly’ [11]. |
T38 |
501-675 |
Sentence |
denotes |
They are a type of oromucosal preparations which are ultra-thin, elegant, stamp sized, portable, patient friendly, and attractive dosage forms across all the age groups [12]. |
T39 |
676-848 |
Sentence |
denotes |
Clinical Data Interchange Standards Consortium (CDISC) defines ODFs as ‘A thin layer or coating which is susceptible to being dissolved when in contact with a liquid’ [13]. |
T40 |
849-1027 |
Sentence |
denotes |
On the contrary, United States Pharmacopoeia (USP) employs a different terminology and called them as ‘Oral Films’ and defined as ‘Thin sheets that are placed in the oral cavity. |
T41 |
1028-1060 |
Sentence |
denotes |
They contain one or more layers. |
T42 |
1061-1106 |
Sentence |
denotes |
A layer might or might not contain API’ [14]. |
T43 |
1107-1298 |
Sentence |
denotes |
ODFs undergo rapid disintegration/dissolution and are usually swallowed along with saliva and a small amount of the drug gets absorbed via the oral mucosa due to its high vasculature [15,16]. |