PMC:7784829 / 4525-5614 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T37 0-298 Sentence denotes Curcumin, a naturally occurring phytochemical and principal component of Curcuma longa, has exhibited broad pharmacological properties including antioxidant, anti-inflammatory, anti-cancer and anti-viral effects (Khor et al., 2019; Kocaadam & Şanlier, 2017; Lal et al., 2016; Wiggers et al., 2017).
T38 299-435 Sentence denotes Curcumin and its derivatives, due to its rich conventional medicinal interest, has undergone comprehensive in vitro and in vivo studies.
T39 436-576 Sentence denotes It has, therefore, been associated with more than 100 cellular targets, including cytokines, proteins, transcription factors, and receptors.
T40 577-791 Sentence denotes Previous studies have shown the potential of curcumin as a treatment against Influenza A virus infection, by an effect mediated by modulating immune response to prevent injury to the lung tissue (Han et al., 2018).
T41 792-920 Sentence denotes Curcumin has also been shown to have anti neuraminidase (NA) activity for the influenza virus NA protein (Richart et al., 2018).
T42 921-1089 Sentence denotes Therefore, in the present study, curcumin and its derivatives were docked onto the spike protein of the SARS-CoV and the SARS-CoV-2 to predict the binding interactions.