PMC:7781431 / 6412-7631 JSONTXT 2 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T44 0-238 Sentence denotes Resolvin (Rv) is a pro-resolving mediator that is derived from omega-3 fatty acids, primarily eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid (DPA), and clupanodonic acid (Duvall and Levy 2016; Serhan et al.
T45 239-245 Sentence denotes 2014).
T46 246-392 Sentence denotes Rvs are divided into several subclasses based on the unique aspects of their structure and/or the straight-chain PUFAs from which they are formed.
T47 393-451 Sentence denotes Resolvin Ds (RvDs) are metabolites of 22-carbon PUFA, DHA.
T48 452-802 Sentence denotes Resolvin Es (RvE) are metabolites of 20 carbons PUFA, EPA; Resolvin Dn-6DPA (RvDn-6DPA) is a DPA isomer, a metabolite of osbond acids; Resolvin Dn-3DPA (RvDn-3DPA) is a DPA isomer, a metabolite of clupanodonic acid; Resolvin Ts (RvT) is a metabolite of clupanodonic acid with 17R-hydroxyl residues, unlike RvDsn-3DPA (all have 17S-hydroxyl residues).
T49 803-948 Sentence denotes AT-RvDs, RvD isomers are synthesized by the aspirin-modified COX-2 enzyme to form 17 (R)-hydroxyl rather than the 17 (S)-hydroxyl residue of RvE.
T50 949-1100 Sentence denotes Cytochrome P450 enzymes that have not yet been characterized may also form this 17 (R)-hydroxy intermediate and contribute to the production of AT-RvE.
T51 1101-1190 Sentence denotes All mentioned Rvs except RvDsn-6DPA are metabolites of omega-3 fatty acids (Serhan et al.
T52 1191-1219 Sentence denotes 2014; Duvall and Levy 2016).