Resolvin (Rv) is a pro-resolving mediator that is derived from omega-3 fatty acids, primarily eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid (DPA), and clupanodonic acid (Duvall and Levy 2016; Serhan et al. 2014). Rvs are divided into several subclasses based on the unique aspects of their structure and/or the straight-chain PUFAs from which they are formed. Resolvin Ds (RvDs) are metabolites of 22-carbon PUFA, DHA. Resolvin Es (RvE) are metabolites of 20 carbons PUFA, EPA; Resolvin Dn-6DPA (RvDn-6DPA) is a DPA isomer, a metabolite of osbond acids; Resolvin Dn-3DPA (RvDn-3DPA) is a DPA isomer, a metabolite of clupanodonic acid; Resolvin Ts (RvT) is a metabolite of clupanodonic acid with 17R-hydroxyl residues, unlike RvDsn-3DPA (all have 17S-hydroxyl residues). AT-RvDs, RvD isomers are synthesized by the aspirin-modified COX-2 enzyme to form 17 (R)-hydroxyl rather than the 17 (S)-hydroxyl residue of RvE. Cytochrome P450 enzymes that have not yet been characterized may also form this 17 (R)-hydroxy intermediate and contribute to the production of AT-RvE. All mentioned Rvs except RvDsn-6DPA are metabolites of omega-3 fatty acids (Serhan et al. 2014; Duvall and Levy 2016).