| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T478 |
0-127 |
Sentence |
denotes |
While across studies, it has become apparent that T cells show robust activation status in severe cases than mild and moderate. |
| T479 |
128-231 |
Sentence |
denotes |
These cells also exhibit exhaustion status, which may occur concomitantly with their activation status. |
| T480 |
232-455 |
Sentence |
denotes |
Deep immune profiling of 125 patients by Mathew et al. (2020) demonstrated that both CD4+ and CD8+ T cells exhibit activation status as revealed by coexpression of CD38 and HLA-DR which corresponded to the disease severity. |
| T481 |
456-581 |
Sentence |
denotes |
Further, these cells were also associated with concomitant expression of proliferation (Ki-67) and exhaustion (PD-1) markers. |
| T482 |
582-780 |
Sentence |
denotes |
This study thus suggests that hyperactivated status of T cells may eventually lead to their exhaustion, and thus these functional and exhaustion features of T cells may reflect the disease severity. |
