PMC:7736111 / 100416-101529 JSONTXT 2 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T591 0-151 Sentence denotes Further, a comparison of various disease states with corresponding antibody response will provide clearer insight as to how this response is regulated.
T592 152-386 Sentence denotes It appears that in patients with severe disease symptoms, TNF-α may influence the GC and hence B cell number (Kaneko et al., 2020), whether the same holds for asymptomatic patients with compromised antibody durability remains elusive.
T593 387-520 Sentence denotes This dynamic antibody response is critical while considering convalescent plasma therapy (CPT) for severe or critically ill patients.
T594 521-653 Sentence denotes If a patient already has sufficient antibodies, CPT may not be a viable treatment option (Anderson et al., 2020; Duan et al., 2020).
T595 654-797 Sentence denotes While many studies have reported success with CPT, some studies have shown no added beneficial effects with this approach (Li L. et al., 2020).
T596 798-1113 Sentence denotes Thus, pre-caution should be taken while using this approach, i.e., if a patient already has adequate virus-specific antibodies or presence of cross-reactive and auto-antibodies, plasma therapy may do more harm than good, which may be the reason with non-responsiveness of CPT in some patients (Nagoba et al., 2020).