PMC:7696151 / 1328-1909 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T14 0-165 Sentence denotes The 4-aminoquinolonehydroxychloroquine (HCQ) was synthesized for the first time in 1946, but its history began as far back as the 1600s thanks to the Incas in Chile.
T15 166-388 Sentence denotes They introduced the special properties of cinchona bark to the Jesuits and in 1820 quinine and cinchonine were isolated and identified as the main alkaloids responsible for the antimalarial activity attributed to the bark.
T16 389-483 Sentence denotes For these reasons, in 1900, the Dutch and British transplanted this “miraculous tree” to Java.
T17 484-581 Sentence denotes The quinine soon began to be also used for the treatment of systemic lupus erythematosus [1,2,3].