Id |
Subject |
Object |
Predicate |
Lexical cue |
T471 |
0-211 |
Sentence |
denotes |
Such uncertain nature of the results is associated with biases present in these studies, which include limited-size sample, heterogeneous experimental designs/clinical status, and the type of IFN isoform tested. |
T472 |
212-406 |
Sentence |
denotes |
In addition, since COVID-19 treatments rarely involve monotherapy, it is difficult to assess whether the results derived from the tested IFN or the drugs used in combination (322, 323, 340–343). |
T473 |
407-663 |
Sentence |
denotes |
It is also worth mentioning that, as discussed above, type I IFN appears to exacerbate inflammation in the progression to severe COVID-19; the timing of administration and subgroups targeted for treatment with type I IFN need to be considered with caution. |