PMC:7652766 / 56410-57050 3 Projects
Annnotations
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T273 | 0-108 | Sentence | denotes | Another important point is the reduction of regulatory T cells CD4+ CD25+ Foxp3+ verified in these patients. |
| T274 | 109-372 | Sentence | denotes | These cells have a fundamental role in the negative regulation of inflammation, control of cell proliferation, and the effector function of several cells, which probably has contributed to the excessive inflammation observed in critically ill patients (153, 190). |
| T275 | 373-640 | Sentence | denotes | It has been described that regulatory T cells play a central role in mitigating the immune response in several viral infections (191); reducing the number of these cells in patients with COVID-19 can lead to loss of regulatory functions and consequent cytokine storm. |