| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T236 |
0-259 |
Sentence |
denotes |
Furthermore, critically ill patients have also manifested rapid proliferation of another subpopulation of monocytes characterized by GM-CSF+ IL-6+, which may be related to inflammatory risk and impairment of the lungs when migrating in large quantities (170). |
| T237 |
260-509 |
Sentence |
denotes |
GM-CSF has been described as an active part of the pathogenesis of autoimmune and inflammatory diseases, mainly in the involvement of myeloid cells, such as monocytes, which can initiate tissue damage in a dependent manner on this marker (174, 175). |
| T238 |
510-921 |
Sentence |
denotes |
In addition, high levels of mediators, such as IL-6, TNF-, and IL-10, found in these patients are likely to have been produced by these monocytes and to be highly involved in cytokine storm and pathogenesis of SARS-CoV-2, since as the disease progresses these mediators reduce, which is correlated to the restoration of the immune function of CD4+ and CD8+ T lymphocytes, which is further discussed later (154). |
