| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T257 |
0-147 |
Sentence |
denotes |
Calcitriol regulates the expression of antimicrobial proteins (cathelicidin and defensin), which directly kill pathogens, especially bacteria [99]. |
| T258 |
148-327 |
Sentence |
denotes |
It inhibits the production of IFN-γ [71] and reduces the expression of pro-inflammatory cytokines by increasing the expression of anti-inflammatory cytokines by macrophages [105]. |
| T259 |
328-535 |
Sentence |
denotes |
Calcitriol modulates antimicrobial proteins (cathelicidin and β-defensin), responsible for modifying the intestinal microbiota, favoring a healthy composition and supporting the intestinal barrier [80, 106]. |
| T260 |
536-788 |
Sentence |
denotes |
It also helps protect the lungs against infection, increases the expression of the tight junction protein, E-cadherin and connexion 43 in the intestine, maintains renal-epithelial barrier function and improves corneal epithelial barrier function [104]. |
