| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T296 |
0-238 |
Sentence |
denotes |
Using PCA, the aFEL for nCOV-2019 and SARS-COV demonstrated that the former occupies only one low energy state whereas the latter forms two distinct low energy basins separated by a metastable state with a barrier of about 6–7.5 kcal/mol. |
| T297 |
239-354 |
Sentence |
denotes |
This confirms that the level of binding for the RBD domain is weaker in SARS-COV due to the presence of two basins. |
| T298 |
355-489 |
Sentence |
denotes |
Similarly, alanine-substitution for a few residues caused the FEL to degenerate into separate multiple low energy regions (Figure S4). |
| T299 |
490-668 |
Sentence |
denotes |
Dominant motions in the RBD are visualized in Figure S5 using the first eigenvector of the PCA. nCOV-2019 and SARS-COV did not show any strong motion in the extended loop region. |
| T300 |
669-838 |
Sentence |
denotes |
Porcupine plots of alanine-mutants demonstrated that mutant N487A shows large motion in the L1 region and Y449A, G447A, and E484A showed large motions in L3 (Figure S5). |
